CN105497796A - Traditional Chinese medicine tablet for treating nasal polyp and preparation method thereof - Google Patents

Traditional Chinese medicine tablet for treating nasal polyp and preparation method thereof Download PDF

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CN105497796A
CN105497796A CN201511024926.5A CN201511024926A CN105497796A CN 105497796 A CN105497796 A CN 105497796A CN 201511024926 A CN201511024926 A CN 201511024926A CN 105497796 A CN105497796 A CN 105497796A
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parts
fructus
radix
chinese medicine
rhizoma
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修海波
辛华
刘喜全
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Abstract

The invention belongs to the field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine tablet for treating nasal polyp and a preparation method thereof. The tablet is prepared from the following traditional Chinese medicinal raw materials in parts by weight: 10-15 parts of rhizoma atractylodis, 15-20 parts of radix angelicae, 10-15 parts of fructus mume, 10-15 parts of fructus schizandrae, 8-10 parts of Chinese honeylocust fruits, 4-6 parts of alum, 8-10 parts of castor beans, 1-3 parts of borneol, 6-8 parts of bombyx batryticatus, 1-3 parts of asarum, 15-20 parts of clove, 15-20 parts of abrotani herba, 6-8 parts of cortex phellodendri, 8-10 parts of nodus nelumbinis rhizomatis charcoal, 8-10 parts of caulis akebiae, 8-10 parts of muskmelon pedicel, 8-10 parts of radix curcumae, 8-10 parts of radix scutellariae, 10-15 parts of cape jasmine, 10-15 parts of flos magnoliae, 10-15 parts of rhizoma cimicifugae, 10-15 parts of folium eriobotryae, 8-10 parts of rhizoma anemarrhenae, 6-8 parts of fritillaria bulb and 10-15 parts of licorice root. The traditional Chinese medicine can be used for removing slough, promoting growth of tissue regeneration, nourishing yin and lung, clearing heat, removing toxicity, suppressing hyperactive liver for descending adverse qi, astringing and stopping bleeding, can be used for treating both symptoms and root cause of nasal polyp with quick response, and can effectively relieve pain of patients.

Description

One treats polypous Chinese medicinal tablet and preparation method thereof
Technical field
The invention belongs to the field of Chinese medicines, particularly one treats polypous Chinese medicinal tablet and preparation method thereof.
Background technology
Nasal polyp is a kind of common nose diseases, be more common in adult, be apt to occur in the place such as middle nasal concha free edge, sieve hole, sieve bubble, Blumenbachs process, semilunar hiatus and apertura maxillaris, nasal polyp is normal relevant with allergic constitution and nasal cavity chronic inflammatory disease, it is non-true neoplasm sagging formed gradually due to nose and paranasal sinuses mucosa extreme edema gravitate, can be one-sided or bilateral.Common symptom is that persistence nasal obstruction to be grown up with polyp volume and increased the weight of.Nasal secretion increases, time with sneeze, secretions can be serosity, mucus, and as concurrent sinus infection, secretions can be purulence, has olfactory disorder more.Nasal obstruction severe one is spoken in closed rhinolalia, snores during sleep.Polyp base of a fruit elder can feel that nasal cavity has thing mobile with breathing.Per nasal expiratory dyspnea when choanal polyp can cause expiration, if polyp blocks eustachian orifice, can cause tinnitus and auditory dysesthesia.Polyp blocks nasal sinuses drain, can cause sinusitis, and patient occurs that bridge of the nose, forehead and Face and cheek distending pain are uncomfortable.
The polypous medicine of current clinical treatment mostly is Western medicine and Chinese patent medicine, likely containing hormone, should not use for a long time, some oral medicines are too strong to the contraction of blood vessel, and life-time service easily develops immunity to drugs, and the course for the treatment of is longer, take effect slow, have certain side effect to health, water preparation nose drops mobility is large, not easily be attached on nasal membrane, life-time service easily causes the shortcomings such as vasomotor rhinitis.The instrument such as nasal polypus snare that traditional operation adopts can only extract the obvious polyp in some positions, and be helpless to the polyp hidden, some large polyps cannot be uprooped again, and residual organizing also can continued growth, causes recurrence.
Summary of the invention
According to the deficiencies in the prior art, the invention provides one can putrefaction-removing granulation-promoting, nourishing YIN and moistening the lung, heat-clearing and toxic substances removing, suppressing hyperactive liver for descending adverse qi, the preparation method of the polypous Chinese medicine formula of anastaltic treatment and tablet thereof.
One disclosed in this invention treats polypous Chinese medicinal tablet, formulated by the raw material of Chinese medicine of following parts by weight: Rhizoma Atractylodis 10-15 part, Radix Angelicae Dahuricae 15-20 part, Fructus Mume 10-15 part, Fructus Schisandrae Chinensis 10-15 part, Fructus Gleditsia 8-10 part, Alumen 4-6 part, Semen Ricini 8-10 part, Borneolum Syntheticum 1-3 part, Bombyx Batryticatus 6-8 part, Herba Asari 1-3 part, Flos Caryophylli 15-20 part, Herba Artemisiae Annuae 15-20 part, Cortex Phellodendri 6-8 part, charred Nodus Nelumbinis Rhizomatis 8-10 part, Caulis Akebiae 8-10 part, Pedicellus Melo 8-10 part, Radix Curcumae 8-10 part, Radix Scutellariae 8-10 part, Fructus Gardeniae 10-15 part, Flos Magnoliae 10-15 part, Rhizoma Cimicifugae 10-15 part, criticize leaf 10-15 part, Rhizoma Anemarrhenae 8-10 part, Bulbus Fritillariae Uninbracteatae 6-8 part, Radix Glycyrrhizae 10-15 part.
One treats polypous Chinese medicinal tablet, preferably formulated by the raw material of Chinese medicine of following parts by weight: Rhizoma Atractylodis 12 parts, the Radix Angelicae Dahuricae 17 parts, Fructus Mume 12 parts, Fructus Schisandrae Chinensis 12 parts, 9 parts, Fructus Gleditsia, Alumen 5 parts, Semen Ricini 9 parts, Borneolum Syntheticum 2 parts, Bombyx Batryticatus 7 parts, Herba Asari 2 parts, Flos Caryophylli 18 parts, Herba Artemisiae Annuae 17 parts, Cortex Phellodendri 7 parts, charred Nodus Nelumbinis Rhizomatis 9 parts, Caulis Akebiae 9 parts, Pedicellus Melo 9 parts, Radix Curcumae 9 parts, Radix Scutellariae 9 parts, Fructus Gardeniae 13 parts, Flos Magnoliae 13 parts, Rhizoma Cimicifugae 13 parts, criticize 12 parts, leaf, the Rhizoma Anemarrhenae 9 parts, Bulbus Fritillariae Uninbracteatae 7 parts, 12 parts, Radix Glycyrrhizae.
A kind of preparation method for the treatment of polypous Chinese medicinal tablet, step is as follows: the first step, is mixed in proportion by each for above-mentioned Chinese medicine raw medicinal material, and adding relative to the determining alcohol of mixture quality 4 ~ 5 times is the ethanol of 85% ~ 90%, reflux 2 ~ 4 hours, obtains the first extracting solution after filtering; It is the ethanol of 90% ~ 95% that the medicinal residues that filtration obtains add relative to the determining alcohol of described medicinal residues quality 2 ~ 3 times again, reflux 1 ~ 3 hour, filters acquisition second extracting solution; First extracting solution and the second extracting solution are merged, concentrating under reduced pressure removing alcohol solvent, obtains after drying and gets dry extract; Second step, is placed on the dry cream that the first step obtains in super micron mill and pulverizes 2 ~ 3 hours, after pulverizing and sieving, obtain 300 order ~ 400 object micropowders; 3rd step, by the micropowders that second step obtains, add the starch relative to the microcrystalline Cellulose of its quality 0.1 ~ 0.3 times, 0.15 ~ 0.3 times of lactose and 0.2 ~ 0.35 times, sieve mix homogeneously, after granulation drying, add the magnesium stearate relative to micropowders quality 0.025 ~ 0.04 times, tablet made by granulate tabletting.
Instructions of taking: sooner or later respectively once, each 1-2 sheet, warm water takes.It within 10 days, is a course for the treatment of.
Pharmacology analysis:
Rhizoma Atractylodis: acrid in the mouth, hardship, warm in nature.Return spleen, stomach, Liver Channel.Can be drying damp and strengthening spleen, expelling wind and cold, improving eyesight.For distension and fullness in the abdomen, have loose bowels, edema, beriberi flaccidity of feet with lamenness, rheumatic arthralgia, anemofrigid cold, nyctalopia.
The Radix Angelicae Dahuricae: acrid in the mouth, warm in nature.Return stomach, large intestine, lung meridian.The wind that can fall apart dehumidifies, understand things pain-stopping, detumescence and apocenosis.For headache due to common cold, supraorbital bone pain, nasal obstruction, nasal sinusitis, toothache, leucorrhea, skin infection swells and ache.
Fructus Mume: sour in the mouth, warm in nature.Liver, spleen, lung, large intestine channel.Can restrain and promote the production of body fluid, relieving colic caused by ascaris anthelmintic.Control chronic cough, deficiency-heat excessive thirst, chronic malaria, chronic diarrhea, dysentery, has blood in stool, hematuria, metrorrhagia, ascariasis of biliary tract stomachache, vomiting, ancylostomiasis, psoriasis, bulbar conjunctiva polyp.
Fructus Schisandrae Chinensis: sour in the mouth, sweet, warm in nature.Return lung, the heart, kidney channel.Can restrain astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, kidney calming.For chronic cough dyspnea due to deficiency, emission, enuresis frequent micturition, incessant chronic diarrhea, spontaneous perspiration, night sweat, Tianjin wound is thirsty, and deficient pulse of losing heart, interior-heat is quenched one's thirst, palpitation and insomnia.
Fructus Gleditsia: acrid in the mouth, warm in nature, micro-poison.Return lung, large intestine channel.Can be dispeled the wind expectorant, except noxious dampness, and parasite killing.Control apoplexy facial hemiparalysis, wind syndrome of head is had a headache, cough phlegm dyspnea, and discharging fresh blood stool, dysentery is kept silent mouth, carbuncle inguinal bubo, skin ulcer tinea mange.
Alumen: sour in the mouth, puckery, cold in nature.Return lung, spleen, liver, large intestine channel.Can to stop blooding antidiarrheal, to dispel wind-phlegm.For incessant chronic diarrhea, have blood in stool, metrorrhagia, epilepsy is gone mad.
Semen Ricini: sweet in the mouth, pungent, property is put down, poisonous.Return large intestine, lung meridian.Can subside a swelling and dial poison, rush down lower logical stagnant.For swollen ulcer drug, sore throat, scrofula, constipation due to dry stool.
Borneolum Syntheticum: acrid in the mouth, hardship, cold nature.GUIXIN, spleen, lung meridian.Can to have one's ideas straightened out refreshment, clearing away heat to alleviate pain.Faint for calentura coma, convulsion, apoplexy syncope due to accumulation of phlegm, stagnation of QI sudden syncope, attacked by pestiferous factors is gone into a coma, and conjunctival congestion, aphtha, laryngopharynx swelling and pain, auditory meatus is suppurated.
Bombyx Batryticatus: salty in the mouth, pungent, property is put down.Return liver, lung, stomach warp.Can expelling wind for relieving convulsion, dissipating phlegm and resolving masses.For convulsion with spasms, laryngopharynx swelling and pain, skin pruritus, submandibular lymph nodes is scorching, facial paralysis.
Herba Asari: acrid in the mouth, warm in nature.GUIXIN, lung, kidney channel.Can expelling wind and cold, understand things pain-stopping, warming the lung to resolve fluid-retention.For anemofrigid cold, headache, toothache, nasal obstruction nasal sinusitis, rheumatic arthralgia, phlegm retention is breathed with cough.
Flos Caryophylli: acrid in the mouth, warm in nature.Return spleen, stomach, lung, kidney channel.Can warming middle-JIAO to send down the adverse QI, reinforcing the kidney and supporting YANG.For Deficiency and coldness of spleen and stomach, singultus is vomitted, lack of appetite and vomiting, trusted subordinate's cold type of pain, impotence due to deficiency of the kidney.
Herba Artemisiae Annuae: bitter in the mouth, pungent, cold in nature.Return liver, gallbladder meridian.Can clearing away summer-heat, except steaming, preventing the attack (or recurrence) of malaria.For pathogenic summer-heat heating, fever due to yin deficiency, night fever abating at dawn, hectic fever due to YIN-deficiency consumptive fever, malaria cold and heat, jaundice due to damp-heat.
Cortex Phellodendri: bitter in the mouth, cold in nature.Return kidney, urinary bladder channel.Can heat clearing and damp drying, pathogenic fire purging except steaming, detoxification sore treatment.For damp-heat dysentery, jaundice, leukorrhagia, pyretic stranguria, beriberi, flaccidity { is warded off }, hectic fever due to YIN-deficiency consumptive fever, night sweat, seminal emission, sore swollen toxin, eczema pruritus.Stir-baked CORTEX PHELLODENDRI with salt solution nourishing YIN to lower pathogenic fire.For hyperactivity of fire caused by deficiency of YIN, night sweat hectic fever due to YIN-deficiency.
Charred Nodus Nelumbinis Rhizomatis: sweet in the mouth, puckery, property is put down.Return liver, lung, stomach warp.Can stop blooding, repercussive.For spitting blood, spitting of blood, hematuria, metrorrhagia.
Caulis Akebiae: bitter in the mouth, cool in nature.GUIXIN, small intestinal, urinary bladder channel.Can pathogenic fire purging row water, promoting blood circulation.Control hot urination, stranguria with turbid discharge, edema, irritable feverish sensation in the chest, sore throat pharyngalgia, inflexible pain all over, women's amenorrhea, galactostasis.
Pedicellus Melo: bitter in the mouth, cold in nature, poisonous.Return spleen, stomach warp.Can tell wind-phlegm dyspepsia, removing water retention by purgation is wet stops drink.Control sputum dyspepsia, be jammed Shangwan, in the heart painful abdominal mass stalk, wind-phlegm epilepsy, jaundice due to damp-heat, extremity edema, nasal obstruction, sore throat.
Radix Curcumae: acrid in the mouth, hardship, cold in nature.Return liver, the heart, lung meridian.Can regulating qi to disperse stagnation, heart fire-clearing upset-relieving, promoting the function of the gallbladder to alleviate jaundice.For amenorrhea dysmenorrhea, chest and abdomen swelling and pain, twinge, calentura coma, epilepsy is gone mad, jaundice dark coloured urine.
Radix Scutellariae: bitter in the mouth, cold in nature.Return lung, gallbladder, spleen, large intestine, small intestine meridian.Can heat clearing and damp drying, eliminating fire and detoxication, hemostasis, antiabortive.For hygropyrexia, fever disease in summer vomiting and nausea uncomfortable in chest, damp and hot feeling of fullness, dysentery, jaundice, cough due to lung-heat, high hot excessive thirst, heat in blood tells nosebleed, carbuncle sore tumefacting virus, frequent fetal movement.
Fructus Gardeniae: bitter in the mouth, cold in nature.GUIXIN, lung, tri-jiao channel.Can pathogenic fire purging relieving restlessness, clearing away heat and promoting diuresis, removing pathogenic heat from blood and toxic substance from the body.Vexed for calentura, jaundice dark coloured urine, blood strangury and dry pain, heat in blood tells nosebleed, conjunctival congestion and swelling pain, pathogenic fire,toxin and furuncles.
Flos Magnoliae: acrid in the mouth, warm in nature.Attach to the lung and stomach meridians.Can dispersing wind and cold, clearing the nasal passage.For headche due to wind-cold, nasal obstruction, nasal sinusitis, turbid nasal discharge.
Rhizoma Cimicifugae: acrid in the mouth, micro-sweet, cold nature.Return lung, spleen, stomach, large intestine channel.Can yang invigorating, deliver, rash, removing toxic substances.Control seasonal epidemic pathogens epidemic disease, headache cold and heat, laryngalgia, aphtha, macule is not saturating; Sinking of QI of middle-JIAO, chronic diarrhea chronic dysentery, proctoptosis, women is collapsed, band, and uterus drops, carbuncle sore tumefacting virus.
Criticize leaf: bitter in the mouth, cold nature.Attach to the lung and stomach meridians.Can clearing away lung-heat to relieve cough, stopping nausea and vomiting by lowering the adverse flow of QI.For cough due to lung-heat, QI rising in reverse order dyspnea with rapid respiration, gastric heat vomiting, dysphoria with smothery sensation is thirsty.
The Rhizoma Anemarrhenae: bitter in the mouth, sweet, cold in nature.Return lung, stomach, kidney channel.Can clearing away heat-fire, promote the production of body fluid and moisturize.For fever caused by exogenous pathogenic factors, high hot excessive thirst, lung-heat type cough, osteopyrexia and fever, interior-heat is quenched one's thirst, dryness of the intestine constipation.
Bulbus Fritillariae Uninbracteatae: bitter in the mouth, cold nature, returns lung meridian, has the merit of clearing heat, eliminating phlegm, relieving cough, can be used for treatment expectorant heat syndrome cough and breathes heavily, yellow thick card of coughing up phlegm; To hold concurrently again sugariness, therefore kind nourishing the lung to arrest cough, treatment lung has the card that scorching cough expectorant is few and sticky, and the deficiency syndrome such as deficiency of YIN cough caused by dryness chronic cough; Also have the merit of eliminating stagnation dissipating depression of QI, the uncomfortable in chest vexed card for the treatment of caused by combination of phlegm and heat, and the disease such as scrofula sucutaneous nodule.
Radix Glycyrrhizae: sweet in the mouth, property is put down, GUIXIN, lung, spleen, stomach warp.Can spleen reinforcing stomach function regulating, Yiqi and vein recovery.QI invigorating invigorating middle warmer; Relieving spasm to stop pain; Nourishing the lung to arrest cough; Eliminating fire and detoxication; Coordinating the actions of various ingredients in a prescription.Cure mainly asthenia lack of appetite; Leanness yellowish complexion; Shortness of breath and palpitation; Stomachache loose stool; The anxious pain of extremity contraction; Hysteria; Cough and asthma; Laryngopharynx swelling and pain; Carbuncle skin ulcer swells and ache; Infantile carbuncle.
Chinese medicine of the present invention can putrefaction-removing granulation-promoting, nourishing YIN and moistening the lung, heat-clearing and toxic substances removing, suppressing hyperactive liver for descending adverse qi, astringing to arrest bleeding, and being used for the treatment of nasal polyp can treating both the principal and secondary aspects of a disease, and instant effect, effectively alleviates the misery of patient.
Now collect 300 Nasal Polyps Patients, take this tablet, sooner or later respectively once, each 1-2 sheet, warm water takes.
Outcome measure:
Cure: symptom, sign disappear completely, and nasal sinuses CT examination is normal.
Effective: nasal cavity pus tears obviously reduce, and have mild nasal congestion, the congested swelling of concha nasalis inferior disappears substantially, and nasal meatus has a small amount of glutinous pus tears, and nasal sinuses CT examination, compare with before treatment, hole chamber increase in density shadow scope obviously reduces.
Invalid: symptom, sign are substantially without improvement.
It within 10 days, is a course for the treatment of.After using 3 course for the treatment of Chinese medicines of the present invention, statistical result is as follows:
Case load Cure number Cure rate Significant figure Invalid number Total effective rate
300 264 88% 27 9 97%
As seen from the above table, after pharmaceutical treatment of the present invention, cure 300 examples, account for 88%, effective 27 examples, account for 9%, no effect 9, account for 3%, overall efficiency is 97%.As can be seen here, the present invention has good effect to polypous treatment.
Attached several routine case is described further:
Case 1:
Grandson so-and-so, female, 13 years old.Because common cold treatment causes nose stream yellow thick nasal discharge amount many not in time, hyposmia, fever with chills, headache, cough with copious phlegm, is diagnosed as suppurative nasal polyp.Take Chinese medicinal tablet of the present invention 10 days, watery nasal discharge reduces, and transfer thin nasal discharge to by yellow thick nasal discharge, headache alleviates, and continues to take 20 days, and nasal mucus is salubrious without, brains, and olfactory sensation recovers, and cures.Take the present invention to cure 3 courses for the treatment of, do not have so far repeatedly.
Case 2:
Jiang, man, 26 years old, turbid nasal discharge 2 weeks was medical, and before 2 years, this trouble patient Zeng Yin suffers from cold and occurs rhinorrhea with clear discharge, after transfer turbid tears to, give Western medicine external collunarium, have no improvement.Now see turbid nasal discharge, sticky and taste is smelly, companion be dizzy, headache, bitter taste, red tongue, thick, yellow and greasy fur.X-ray shows that frontal sinusitis sexually revises, and is diagnosed as " chronic nasal polyp ", and oral Chinese medicinal tablet 1 of the present invention takes a turn for the better the course for the treatment of, fully recovers, pay a return visit without recurrence, do not have so far repeatedly after half a year after treating 5 courses for the treatment of.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is described in detail, but the present invention is not limited to specific embodiment.
Embodiment 1:
One treats polypous Chinese medicinal tablet, formulated by the raw material of Chinese medicine of following parts by weight: Rhizoma Atractylodis 15 parts, the Radix Angelicae Dahuricae 15 parts, Fructus Mume 15 parts, Fructus Schisandrae Chinensis 10 parts, 10 parts, Fructus Gleditsia, Alumen 4 parts, Semen Ricini 10 parts, Borneolum Syntheticum 1 part, Bombyx Batryticatus 8 parts, Herba Asari 1 part, Flos Caryophylli 20 parts, Herba Artemisiae Annuae 15 parts, Cortex Phellodendri 8 parts, charred Nodus Nelumbinis Rhizomatis 8 parts, Caulis Akebiae 10 parts, Pedicellus Melo 8 parts, Radix Curcumae 10 parts, Radix Scutellariae 8 parts, Fructus Gardeniae 15 parts, Flos Magnoliae 10 parts, Rhizoma Cimicifugae 15 parts, criticize 10 parts, leaf, the Rhizoma Anemarrhenae 10 parts, Bulbus Fritillariae Uninbracteatae 6 parts, 15 parts, Radix Glycyrrhizae.
Embodiment 2:
One treats polypous Chinese medicinal tablet, formulated by the raw material of Chinese medicine of following parts by weight: Rhizoma Atractylodis 10 parts, the Radix Angelicae Dahuricae 20 parts, Fructus Mume 10 parts, Fructus Schisandrae Chinensis 15 parts, 8 parts, Fructus Gleditsia, Alumen 6 parts, Semen Ricini 8 parts, Borneolum Syntheticum 3 parts, Bombyx Batryticatus 6 parts, Herba Asari 3 parts, Flos Caryophylli 15 parts, Herba Artemisiae Annuae 20 parts, Cortex Phellodendri 6 parts, charred Nodus Nelumbinis Rhizomatis 10 parts, Caulis Akebiae 8 parts, Pedicellus Melo 10 parts, Radix Curcumae 8 parts, Radix Scutellariae 10 parts, Fructus Gardeniae 10 parts, Flos Magnoliae 15 parts, Rhizoma Cimicifugae 10 parts, criticize 15 parts, leaf, the Rhizoma Anemarrhenae 8 parts, Bulbus Fritillariae Uninbracteatae 8 parts, 10 parts, Radix Glycyrrhizae.
Embodiment 3:
One treats polypous Chinese medicinal tablet, formulated by the raw material of Chinese medicine of following parts by weight: Rhizoma Atractylodis 12 parts, the Radix Angelicae Dahuricae 17 parts, Fructus Mume 12 parts, Fructus Schisandrae Chinensis 12 parts, 9 parts, Fructus Gleditsia, Alumen 5 parts, Semen Ricini 9 parts, Borneolum Syntheticum 2 parts, Bombyx Batryticatus 7 parts, Herba Asari 2 parts, Flos Caryophylli 18 parts, Herba Artemisiae Annuae 17 parts, Cortex Phellodendri 7 parts, charred Nodus Nelumbinis Rhizomatis 9 parts, Caulis Akebiae 9 parts, Pedicellus Melo 9 parts, Radix Curcumae 9 parts, Radix Scutellariae 9 parts, Fructus Gardeniae 13 parts, Flos Magnoliae 13 parts, Rhizoma Cimicifugae 13 parts, criticize 12 parts, leaf, the Rhizoma Anemarrhenae 9 parts, Bulbus Fritillariae Uninbracteatae 7 parts, 12 parts, Radix Glycyrrhizae.
Embodiment 4:
A kind of preparation method for the treatment of polypous Chinese medicinal tablet, step is as follows: the first step, is mixed in proportion according to each raw medicinal material of the Chinese medicine in embodiment 1, and adding relative to the determining alcohol of mixture quality 4 times is the ethanol of 85%, reflux 2 hours, obtains the first extracting solution after filtering; It is the ethanol of 90% that the medicinal residues that filtration obtains add relative to the determining alcohol of described medicinal residues quality 2 times again, reflux 1 hour, filters acquisition second extracting solution; First extracting solution and the second extracting solution are merged, concentrating under reduced pressure removing alcohol solvent, obtains after drying and gets dry extract; Second step, is placed on the dry cream that the first step obtains in super micron mill and pulverizes 2 hours, after pulverizing and sieving, obtain 300 object micropowders; 3rd step, by the micropowders that second step obtains, adds the starch relative to the microcrystalline Cellulose of its quality 0.1 times, 0.15 times of lactose and 0.2 times, sieve mix homogeneously, after granulation drying, add the magnesium stearate relative to micropowders quality 0.025 times, tablet made by granulate tabletting.
Instructions of taking: sooner or later respectively once, each 1-2 sheet, warm water takes.It within 10 days, is a course for the treatment of.
Embodiment 5:
A kind of preparation method for the treatment of polypous Chinese medicinal tablet, step is as follows: the first step, is mixed in proportion according to each raw medicinal material of the Chinese medicine in embodiment 2, and adding relative to the determining alcohol of mixture quality 5 times is the ethanol of 90%, reflux 4 hours, obtains the first extracting solution after filtering; It is the ethanol of 95% that the medicinal residues that filtration obtains add relative to the determining alcohol of described medicinal residues quality 3 times again, reflux 3 hours, filters acquisition second extracting solution; First extracting solution and the second extracting solution are merged, concentrating under reduced pressure removing alcohol solvent, obtains after drying and gets dry extract; Second step, is placed on the dry cream that the first step obtains in super micron mill and pulverizes 3 hours, after pulverizing and sieving, obtain 400 object micropowders; 3rd step, by the micropowders that second step obtains, adds the starch relative to the microcrystalline Cellulose of its quality 0.3 times, 0.3 times of lactose and 0.35 times, sieve mix homogeneously, after granulation drying, add the magnesium stearate relative to micropowders quality 0.04 times, tablet made by granulate tabletting.
Instructions of taking: sooner or later respectively once, each 1-2 sheet, warm water takes.It within 10 days, is a course for the treatment of.
Embodiment 6:
A kind of preparation method for the treatment of polypous Chinese medicinal tablet, step is as follows: the first step, is mixed in proportion according to each raw medicinal material of the Chinese medicine in embodiment 3, and adding relative to the determining alcohol of mixture quality 4.5 times is the ethanol of 88%, reflux 3 hours, obtains the first extracting solution after filtering; It is the ethanol of 92% that the medicinal residues that filtration obtains add relative to the determining alcohol of described medicinal residues quality 2.5 times again, reflux 2 hours, filters acquisition second extracting solution; First extracting solution and the second extracting solution are merged, concentrating under reduced pressure removing alcohol solvent, obtains after drying and gets dry extract; Second step, is placed on the dry cream that the first step obtains in super micron mill and pulverizes 2.5 hours, after pulverizing and sieving, obtain 350 object micropowders; 3rd step, by the micropowders that second step obtains, adds the starch relative to the microcrystalline Cellulose of its quality 0.2 times, 0.2 times of lactose and 0.3 times, sieve mix homogeneously, after granulation drying, add the magnesium stearate relative to micropowders quality 0.03 times, tablet made by granulate tabletting.
Instructions of taking: sooner or later respectively once, each 1-2 sheet, warm water takes.It within 10 days, is a course for the treatment of.
Below the present invention be described in detail, the above, be only the preferred embodiment of the present invention, when not limiting the scope of the present invention, namely allly does impartial change according to the application's scope and modify, all should still belong in covering scope of the present invention.

Claims (3)

1. the polypous Chinese medicinal tablet for the treatment of, it is characterized in that, formulated by the raw material of Chinese medicine of following parts by weight: Rhizoma Atractylodis 10-15 part, Radix Angelicae Dahuricae 15-20 part, Fructus Mume 10-15 part, Fructus Schisandrae Chinensis 10-15 part, Fructus Gleditsia 8-10 part, Alumen 4-6 part, Semen Ricini 8-10 part, Borneolum Syntheticum 1-3 part, Bombyx Batryticatus 6-8 part, Herba Asari 1-3 part, Flos Caryophylli 15-20 part, Herba Artemisiae Annuae 15-20 part, Cortex Phellodendri 6-8 part, charred Nodus Nelumbinis Rhizomatis 8-10 part, Caulis Akebiae 8-10 part, Pedicellus Melo 8-10 part, Radix Curcumae 8-10 part, Radix Scutellariae 8-10 part, Fructus Gardeniae 10-15 part, Flos Magnoliae 10-15 part, Rhizoma Cimicifugae 10-15 part, criticize leaf 10-15 part, Rhizoma Anemarrhenae 8-10 part, Bulbus Fritillariae Uninbracteatae 6-8 part, Radix Glycyrrhizae 10-15 part.
2. one according to claim 1 treats polypous Chinese medicinal tablet, it is characterized in that, formulated by the raw material of Chinese medicine of following parts by weight: Rhizoma Atractylodis 12 parts, the Radix Angelicae Dahuricae 17 parts, Fructus Mume 12 parts, Fructus Schisandrae Chinensis 12 parts, 9 parts, Fructus Gleditsia, Alumen 5 parts, Semen Ricini 9 parts, Borneolum Syntheticum 2 parts, Bombyx Batryticatus 7 parts, Herba Asari 2 parts, Flos Caryophylli 18 parts, Herba Artemisiae Annuae 17 parts, Cortex Phellodendri 7 parts, charred Nodus Nelumbinis Rhizomatis 9 parts, Caulis Akebiae 9 parts, Pedicellus Melo 9 parts, Radix Curcumae 9 parts, Radix Scutellariae 9 parts, Fructus Gardeniae 13 parts, Flos Magnoliae 13 parts, Rhizoma Cimicifugae 13 parts, criticizes 12 parts, leaf, the Rhizoma Anemarrhenae 9 parts, Bulbus Fritillariae Uninbracteatae 7 parts, 12 parts, Radix Glycyrrhizae.
3. the preparation method of the polypous Chinese medicinal tablet for the treatment of according to claim 1, it is characterized in that step is as follows: the first step, each for above-mentioned Chinese medicine raw medicinal material is mixed in proportion, adding relative to the determining alcohol of mixture quality 4 ~ 5 times is the ethanol of 85% ~ 90%, reflux 2 ~ 4 hours, obtains the first extracting solution after filtering; It is the ethanol of 90% ~ 95% that the medicinal residues that filtration obtains add relative to the determining alcohol of described medicinal residues quality 2 ~ 3 times again, reflux 1 ~ 3 hour, filters acquisition second extracting solution; First extracting solution and the second extracting solution are merged, concentrating under reduced pressure removing alcohol solvent, obtains after drying and gets dry extract; Second step, is placed on the dry cream that the first step obtains in super micron mill and pulverizes 2 ~ 3 hours, after pulverizing and sieving, obtain 300 order ~ 400 object micropowders; 3rd step, by the micropowders that second step obtains, add the starch relative to the microcrystalline Cellulose of its quality 0.1 ~ 0.3 times, 0.15 ~ 0.3 times of lactose and 0.2 ~ 0.35 times, sieve mix homogeneously, after granulation drying, add the magnesium stearate relative to micropowders quality 0.025 ~ 0.04 times, tablet made by granulate tabletting.
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CN107625910A (en) * 2017-11-24 2018-01-26 马雪英 A kind of medicine for treating nasal polyp and preparation method thereof

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