CN105496798A - Powder-filled hydrogel and preparing method and application thereof - Google Patents

Powder-filled hydrogel and preparing method and application thereof Download PDF

Info

Publication number
CN105496798A
CN105496798A CN201511002826.2A CN201511002826A CN105496798A CN 105496798 A CN105496798 A CN 105496798A CN 201511002826 A CN201511002826 A CN 201511002826A CN 105496798 A CN105496798 A CN 105496798A
Authority
CN
China
Prior art keywords
powder
filled hydrogel
powder filled
hydrogel
sodium
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN201511002826.2A
Other languages
Chinese (zh)
Other versions
CN105496798B (en
Inventor
陈思
王旭
周波
马猛
吴波震
施燕琴
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zhejiang University of Technology ZJUT
Original Assignee
Zhejiang University of Technology ZJUT
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zhejiang University of Technology ZJUT filed Critical Zhejiang University of Technology ZJUT
Priority to CN201511002826.2A priority Critical patent/CN105496798B/en
Publication of CN105496798A publication Critical patent/CN105496798A/en
Application granted granted Critical
Publication of CN105496798B publication Critical patent/CN105496798B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/04—Dispersions; Emulsions
    • A61K8/042—Gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • A61K8/25—Silicon; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/731—Cellulose; Quaternized cellulose derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73—Polysaccharides
    • A61K8/733—Alginic acid; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • A61K8/8147—Homopolymers or copolymers of acids; Metal or ammonium salts thereof, e.g. crotonic acid, (meth)acrylic acid; Compositions of derivatives of such polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/10—General cosmetic use
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/52—Stabilizers

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Zoology (AREA)
  • Dispersion Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Cosmetics (AREA)

Abstract

The invention discloses powder-filled hydrogel. The powder-filled hydrogel is prepared from, by mass, 0.5 part of powder, 0.05-0.5 part of gelator and 5-20 parts of solvent. The powder is prepared from plant powder for cosmetics, pearl powder and inorganic particles for cosmetics. The gelator is obtained by mixing one or more of sodium polyacrylate, sodium carboxymethylcellulose, carboxymethyl cellulose sodium, polyacrylic acid copolymer, sodium alga acid and Carbomer. The gelator is free of toxicity, safe, low in price and free of pollution and facilitates the application and popularization of the gel product. The powder-filled hydrogel is high in stability, free of delamination, easy to store, easy to absorb and good in smear feeing and can be widely applied to the field of cosmetics.

Description

A kind of powder filled hydrogel and preparation and application thereof
(1) technical field
The present invention relates to a kind of powder filled hydrogel, particularly one powder filled hydrogel used for cosmetic and preparation and application thereof.
(2) background technology
Margarita powder and natural vegetable powder have excellent skin whitening effects, are more and more subject to the welcome of consumer.Modern study shows, Margarita powder all has the effect of uniqueness in body immunity, slow down aging, freckle removing and whitening, supplement calcium etc. improving.The Pharmacopoeia of the People's Republic of China and " Chinese medicine voluminous dictionary " all indicate: Margarita has the effects such as arresting convulsion of calming the nerves, improving eyesight removing nebula, removing toxic substances and promoting granulation.The natural vegetable powder of whitening can there be Flos Rosae Rugosae powder, Aloe powder, Radix Angelicae Dahuricae powder, Poria powder etc.Flos Rosae Rugosae powder is rich in amino acid needed by human body, protein, organic acid vitamin C etc., and containing three rare elements abundant greatly: natural anthocyanidin, natural fiavanoids element, natural total polyphenols.And Aloe powder has treatment comedo and swollen wart, slow down aging, hair care, prevents the effect of poliosis and alopecia.Radix Angelicae Dahuricae powder can improve local blood circulation, eliminates pigment excess accumulation in the tissue, promotes skin cell metabolism, and then reaches the effect of beauty treatment, the Compendium of Material Medica meaning Radix Angelicae Dahuricae " longue skin, moist color, can make face fat ".
Using method at present about Margarita powder or Plant Powder mainly contains two kinds: one, consumer arranges in pairs or groups use from being about to Margarita powder or Plant Powder and water or essence; Two, by Margarita powder or Plant Powder and water and EDTA-Na 2, allantoin, glycerol, propylene glycol, Herba Menthae, MEIGUI CHUNLU, the auxiliary agent such as amino acid humectant directly mix, the mixing paste solidifying body obtained containing pressed powder directly uses.Method one cannot meet consumer and use simple demand efficiently again to product, and paste solidifying body prepared by method two has bad, the easy layering of stability usually, not easily preserves, not easily absorb, smear and feel the shortcoming such as bad.The present invention is directed to above-mentioned technical barrier, design and develop a kind of preparation method of the novel powder filled hydrogel for cosmetic use.
(3) summary of the invention
The present invention seeks in order to solve existing Margarita powder or Plant Powder fill obtain bad, the easy layering of paste solidifying body stability, not easily preserves, not easily absorb, smear and feel the problem such as bad, the invention provides a kind of novel powder filled hydrogel for cosmetic use and preparation method thereof and application, can cosmetic field be widely used in.
The technical solution used in the present invention is:
The invention provides a kind of powder filled hydrogel, described powder filled hydrogel is made up of the raw material of following quality proportioning: powder body 0.5 part, gelator 0.05 ~ 0.5 part, solvent 5 ~ 20 parts;
Described powder body comprises Plant Powder used for cosmetic, Margarita powder and inorganic particulate used for cosmetic;
Described gelator is one or both and above mixing in sodium polyacrylate, sodium carboxymethyl cellulose, Carboxymethyl cellulose sodium, acrylic copolymer, sodium alginate, carbomer;
Described solvent is deionized water or essence; Described essence is essence used for cosmetic well known in the art, and preferred mass consists of: deionized water 76.8 parts, glycerol 6 parts, propylene glycol 10 parts, polyacrylic acid 3 parts, MEIGUI CHUNLU 0.2 part and amino acid humectant 4 parts.
Further, described diameter of particle is 2000 ~ 3000 orders.
Further, described powder body is the one in Margarita powder, Flos Rosae Rugosae powder, Aloe powder, Radix Angelicae Dahuricae powder, Poria powder, nano-calcium carbonate or nano silicon.
Further, described gelator is one of following: sodium polyacrylate, sodium carboxymethyl cellulose, Carboxymethyl cellulose sodium, acrylic copolymer, sodium alginate; Described sodium polyacrylate molecular weight is 4,000,000-500 ten thousand, and described acrylic copolymer molecular weight is 2,000,000-300 ten thousand.
Further, described gelator is one of following: (1) sodium alginate mixes with carbomer mass ratio 2:1's; (2) the mixing of sodium alginate and carbomer mass ratio 2:1; (3) the mixing of sodium alginate and sodium polyacrylate mass ratio 2:1.Described carbomer is Acritamer 940.
Further, described powder filled hydrogel is made up of the raw material of following quality proportioning: powder body 0.5 part, gelator 0.1 ~ 0.3 part, solvent 10 parts.
The present invention also provides a kind of preparation method of described powder filled hydrogel, and described method is: by formula ratio, powder body dissolution with solvents is made suspension, stirs, add gelator, and ultrasonic disperse is even, obtains powder filled hydrogel.
Further, described supersonic frequency is 40KHz, ultrasonic time 10 ~ 30min.
The present invention also provides a kind of described powder filled hydrogel preparing the application in cosmetic emulsion.
In powder body of the present invention, Margarita powder, Flos Rosae Rugosae powder, Aloe powder, Radix Angelicae Dahuricae powder, Poria powder all adopt airflow pulverization method to prepare.
Compared with prior art, the present invention has following beneficial effect:
1, gelator non-toxic and safe of the present invention, low price and pollution-free, is conducive to applying of gel products of the present invention.
2, powder filled hydrogel good stability of the present invention, not stratified, easy preservation, easily absorb, smear sense well, the powder filled hydrogel of the present invention, at the centrifugal 10min of 4000r/min, all without obvious lamination, can be widely used in cosmetic field.
(4) detailed description of the invention
Below in conjunction with specific embodiment, the present invention is described further, but protection scope of the present invention is not limited in this:
Described in the embodiment of the present invention, essence quality group becomes: deionized water 76.8 parts, glycerol 6 parts, propylene glycol 10 parts, polyacrylic acid 3 parts, MEIGUI CHUNLU 0.2 part and amino acid humectant 4 parts.
Stability test centrifugal rotational speed 4000r/min described in the embodiment of the present invention, system is not stratified, then have 1 ~ 2 year shelf-life.
Embodiment 1:
(1) powder filled hydrogel formulation 1: Margarita powder 0.5g (particle diameter 2000 ~ 3000 order), Carboxymethyl cellulose sodium 0.3g, deionized water 10g.
(2) powder filled hydrogel formulation 2: Margarita powder 0.5g (particle diameter 2000 ~ 3000 order), Carboxymethyl cellulose sodium 0.3g, essence 10g.
(3) powder filled hydrogel preparation: according to formula ratio, respectively Margarita powder deionized water and essence are configured Margarita powder suspension as solvent, magnetic agitation limit, limit adds formula ratio gelator Carboxymethyl cellulose sodium, continues stirring 1 hour.Then by ultrasonic 20 minutes of hydrogel (40KHz) in sonic cleaning device, powder filled hydrogel is obtained.
Stability test: powder filled hydrogel is centrifugal on centrifuge, centrifugal 10min, rotating speed 4000r/min, observe its degeee of stratification.
Embodiment 2:
(1) powder filled hydrogel formulation 1: Aloe powder 0.5g (particle diameter 2000 ~ 3000 order), Carboxymethyl cellulose sodium 0.3g, deionized water 10g.
(2) powder filled hydrogel formulation 2: Aloe powder 0.5g (particle diameter 2000 ~ 3000 order), Carboxymethyl cellulose sodium 0.3g, essence 10g.
(3) powder filled hydrogel preparation: according to formula ratio, respectively Aloe powder deionized water and essence are configured Aloe powder suspension as solvent, magnetic agitation limit, limit adds formula ratio gelator Carboxymethyl cellulose sodium, continues stirring 1 hour.Then by ultrasonic 20 minutes of hydrogel (40KHz) in sonic cleaning device, powder filled hydrogel is obtained.
Stability test: powder filled hydrogel is centrifugal on centrifuge, centrifugal 10min, rotating speed 4000r/min, observe its degeee of stratification.
Embodiment 3:
(1) powder filled hydrogel formulation 1: Flos Rosae Rugosae powder 0.5g (particle diameter 2000 ~ 3000 order), Carboxymethyl cellulose sodium 0.3g, deionized water 10g.
(2) powder filled hydrogel formulation 2: Flos Rosae Rugosae powder 0.5g (particle diameter 2000 ~ 3000 order), Carboxymethyl cellulose sodium 0.3g, essence 10g.
(3) powder filled hydrogel preparation: according to formula ratio, respectively Flos Rosae Rugosae powder deionized water and essence are configured Flos Rosae Rugosae powder suspension as solvent, magnetic agitation limit, limit adds formula ratio gelator Carboxymethyl cellulose sodium, continues stirring 1 hour.Then by ultrasonic 20 minutes of hydrogel (40KHz) in sonic cleaning device, powder filled hydrogel is obtained.
Stability test: powder filled hydrogel is centrifugal on centrifuge, centrifugal 10min, rotating speed 4000r/min, observe its degeee of stratification.
Embodiment 4:
(1) powder filled hydrogel formulation 1: Radix Angelicae Dahuricae powder 0.5g (particle diameter 2000 ~ 3000 order), Carboxymethyl cellulose sodium 0.3g, deionized water 10g.
(2) powder filled hydrogel formulation 2: Radix Angelicae Dahuricae powder 0.5g (particle diameter 2000 ~ 3000 order), Carboxymethyl cellulose sodium 0.3g, essence 10g.
(3) powder filled hydrogel preparation: according to formula ratio, respectively Radix Angelicae Dahuricae powder deionized water and essence are configured Radix Angelicae Dahuricae powder suspension as solvent, magnetic agitation limit, limit adds formula ratio gelator Carboxymethyl cellulose sodium, continues stirring 1 hour.Then by ultrasonic 20 minutes of hydrogel (40KHz) in sonic cleaning device, powder filled hydrogel is obtained.
Stability test: powder filled hydrogel is centrifugal on centrifuge, centrifugal 10min, rotating speed 4000r/min, observe its degeee of stratification.
Embodiment 5:
(1) powder filled hydrogel formulation 1: Poria powder 0.5g (particle diameter 2000 ~ 3000 order), Carboxymethyl cellulose sodium 0.3g, deionized water 10g.
(2) powder filled hydrogel formulation 2: Poria powder 0.5g (particle diameter 2000 ~ 3000 order), Carboxymethyl cellulose sodium 0.3g, essence 10g.
(3) powder filled hydrogel preparation: according to formula ratio, respectively Poria powder deionized water and essence are configured Poria powder suspension as solvent, magnetic agitation limit, limit adds formula ratio gelator Carboxymethyl cellulose sodium, continues stirring 1 hour.Then by ultrasonic 20 minutes of hydrogel (40KHz) in sonic cleaning device, powder filled hydrogel is obtained.
Stability test: powder filled hydrogel is centrifugal on centrifuge, centrifugal 10min, rotating speed 4000r/min, observe its degeee of stratification.
Embodiment 6:
(1) powder filled hydrogel formulation 1: nano-calcium carbonate 0.5g (particle diameter 2000 ~ 3000 order), Carboxymethyl cellulose sodium 0.3g, deionized water 10g.
(2) powder filled hydrogel formulation 2: nano-calcium carbonate 0.5g (particle diameter 2000 ~ 3000 order), Carboxymethyl cellulose sodium 0.3g, essence 10g.
(3) powder filled hydrogel preparation: according to formula ratio, respectively nano-calcium carbonate deionized water and essence are configured nano calcium carbonate suspension as solvent, magnetic agitation limit, limit adds formula ratio gelator Carboxymethyl cellulose sodium, continues stirring 1 hour.Then by ultrasonic 20 minutes of hydrogel (40KHz) in sonic cleaning device, powder filled hydrogel is obtained.
Stability test: powder filled hydrogel is centrifugal on centrifuge, centrifugal 10min, rotating speed 4000r/min, observe its degeee of stratification.
Embodiment 7:
(1) powder filled hydrogel formulation 1: nano silicon 0.5g (particle diameter 2000 ~ 3000 order), Carboxymethyl cellulose sodium 0.3g, deionized water 10g.
(2) powder filled hydrogel formulation 2: nano silicon 0.5g (particle diameter 2000 ~ 3000 order), Carboxymethyl cellulose sodium 0.3g, essence 10g.
(3) powder filled hydrogel preparation: according to formula ratio, respectively nano silicon deionized water and essence are configured nanometer titanium dioxide silicon suspension as solvent, magnetic agitation limit, limit adds formula ratio gelator Carboxymethyl cellulose sodium, continues stirring 1 hour.Then by ultrasonic 20 minutes of hydrogel (40KHz) in sonic cleaning device, powder filled hydrogel is obtained.
Stability test: powder filled hydrogel is centrifugal on centrifuge, centrifugal 10min, rotating speed 4000r/min, observe its degeee of stratification.
Embodiment 8:
(1) powder filled hydrogel formulation 1: Margarita powder 0.5g (particle diameter 2000 ~ 3000 order), carbomer 0.1g, deionized water 10g.
(2) powder filled hydrogel formulation 2: Margarita powder 0.5g (particle diameter 2000 ~ 3000 order), carbomer 0.1g, essence 10g.
(3) powder filled hydrogel preparation: according to formula ratio, respectively Margarita powder deionized water and essence are configured Margarita powder suspension as solvent, magnetic agitation limit, limit adds formula ratio gelator carbomer, continues stirring 1 hour.Then by ultrasonic 20 minutes of hydrogel (40kHz) in sonic cleaning device, powder filled hydrogel is obtained.
Stability test: powder filled hydrogel is centrifugal on centrifuge, centrifugal 10min, rotating speed 4000r/min, observe its degeee of stratification.
Embodiment 9:
(1) powder filled hydrogel formulation 1: Margarita powder 0.5g (particle diameter 2000 ~ 3000 order), sodium polyacrylate (molecular weight is 4,000,000-500 ten thousand) 0.1g, deionized water 10g.
(2) powder filled hydrogel formulation 2: Margarita powder 0.5g (particle diameter 2000 ~ 3000 order), sodium polyacrylate (molecular weight is 4,000,000-500 ten thousand) 0.1g, essence 10g.
(3) powder filled hydrogel preparation: according to formula ratio, respectively Margarita powder deionized water and essence are configured Margarita powder suspension as solvent, magnetic agitation limit, limit adds formula ratio gelator sodium polyacrylate, continues stirring 1 hour.Then by ultrasonic 20 minutes of hydrogel (40kHz) in sonic cleaning device, powder filled hydrogel is obtained.
Stability test: powder filled hydrogel is centrifugal on centrifuge, centrifugal 10min, rotating speed 4000r/min, observe its degeee of stratification.
Embodiment 10:
(1) powder filled hydrogel formulation 1: Margarita powder 0.5g (particle diameter 2000 ~ 3000 order), sodium carboxymethyl cellulose 0.3g, deionized water 10g.
(2) powder filled hydrogel formulation 2: Margarita powder 0.5g (particle diameter 2000 ~ 3000 order), sodium carboxymethyl cellulose 0.3g, essence 10g.
(3) powder filled hydrogel preparation: according to formula ratio, respectively Margarita powder deionized water and essence are configured Margarita powder suspension as solvent, magnetic agitation limit, limit adds formula ratio gelator sodium carboxymethyl cellulose, continues stirring 1 hour.Then by ultrasonic 20 minutes of hydrogel (40kHz) in sonic cleaning device, powder filled hydrogel is obtained.
Stability test: powder filled hydrogel is centrifugal on centrifuge, centrifugal 10min, rotating speed 4000r/min, observe its degeee of stratification.
Embodiment 11:
(1) powder filled hydrogel formulation 1: Margarita powder 0.5g (particle diameter 2000 ~ 3000 order), sodium alginate 0.3g, deionized water 10g.
(2) powder filled hydrogel formulation 2: Margarita powder 0.5g (particle diameter 2000 ~ 3000 order), sodium alginate 0.3g, essence 10g.
(3) powder filled hydrogel preparation: according to formula ratio, respectively Margarita powder deionized water and essence are configured Margarita powder suspension as solvent, magnetic agitation limit, limit adds formula ratio gelator sodium alginate, continues stirring 1 hour.Then by ultrasonic 20 minutes of hydrogel (40kHz) in sonic cleaning device, powder filled hydrogel is obtained.
Stability test: powder filled hydrogel is centrifugal on centrifuge, centrifugal 10min, rotating speed 4000r/min, observe its degeee of stratification.
Embodiment 12:
(1) powder filled hydrogel formulation 1: Margarita powder 0.5g (particle diameter 2000 ~ 3000 order), sodium alginate 0.1g, carbomer 0.05g, deionized water 10g.
(2) powder filled hydrogel formulation 2: Margarita powder 0.5g (particle diameter 2000 ~ 3000 order), sodium alginate 0.1g, carbomer 0.05g, essence 10g.
(3) powder filled hydrogel preparation: according to formula ratio, respectively Margarita powder deionized water and essence are configured Margarita powder suspension as solvent, magnetic agitation limit, limit adds formula ratio gelator sodium alginate and carbomer, continues stirring 1 hour.Then by ultrasonic 20 minutes of hydrogel (40kHz) in sonic cleaning device, powder filled hydrogel is obtained.
Stability test: powder filled hydrogel is centrifugal on centrifuge, centrifugal 10min, rotating speed 4000r/min, observe its degeee of stratification.
Embodiment 13:
(1) powder filled hydrogel formulation 1: Margarita powder 0.5g (particle diameter 2000 ~ 3000 order), Carboxymethyl cellulose sodium 0.1g, carbomer 0.05g, deionized water 10g.
(2) powder filled hydrogel formulation 2: Margarita powder 0.5g (particle diameter 2000 ~ 3000 order), Carboxymethyl cellulose sodium 0.1g, carbomer 0.05g, essence 10g.
(3) powder filled hydrogel preparation: according to formula ratio, respectively Margarita powder deionized water and essence are configured Margarita powder suspension as solvent, magnetic agitation limit, limit adds formula ratio gelator Carboxymethyl cellulose sodium and carbomer, continues stirring 1 hour.Then by ultrasonic 20 minutes of hydrogel (40kHz) in sonic cleaning device, powder filled hydrogel is obtained.
Stability test: powder filled hydrogel is centrifugal on centrifuge, centrifugal 10min, rotating speed 4000r/min, observe its degeee of stratification.
Embodiment 14:
(1) powder filled hydrogel formulation 1: Margarita powder 0.5g (particle diameter 2000 ~ 3000 order), sodium alginate 0.1g, sodium polyacrylate (molecular weight 4,000,000-500 ten thousand) 0.05g, deionized water 10g.
(2) powder filled hydrogel formulation 2: Margarita powder 0.5g (particle diameter 2000 ~ 3000 order), sodium alginate 0.1g, sodium polyacrylate (molecular weight 4,000,000-500 ten thousand) 0.05g, essence 10g.
(3) powder filled hydrogel preparation: according to formula ratio, respectively Margarita powder deionized water and essence are configured Margarita powder suspension as solvent, magnetic agitation limit, limit adds formula ratio gelator sodium alginate and sodium polyacrylate, continues stirring 1 hour.Then by ultrasonic 20 minutes of hydrogel (40kHz) in sonic cleaning device, powder filled hydrogel is obtained.
Stability test: by powder filled hydrogel at the centrifugal 10min of 4000r/min, observe its degeee of stratification, result shows, and the powder filled hydrogel of example 1 ~ 14 is all without obvious lamination.
Smear sense evaluation to the powder filled hydrogel of example 1 ~ 14 below, comprehensive granular sensation, sticky hands degree, skid level and powder body absorbing state evaluate level of comfort.Total score is 0,1,2,3,4,5,0 to be divided into and uncomfortable from low to high, and 5 are divided into the most comfortable.Valuation officer 5, valuation officer 3 female 2 man.
The sensory evaluation (solvent is water) in different powder body (embodiment 1 ~ 7 formula 1) of table 1 gelator Carboxymethyl cellulose sodium
The sensory evaluation (solvent is water) in Margarita powder (embodiment 1, embodiment 8 ~ 11 formula 1) of table 2 gelator
The composite sensory evaluation (solvent is water) in Margarita powder (embodiment 12 ~ 14 formula 1) of table 3 gelator
In the middle sensory evaluation of different powder body (embodiment 1 ~ 7 formula 2), (solvent is table 4 gelator Carboxymethyl cellulose sodium
Essence)
The sensory evaluation (solvent is essence) in Margarita powder (embodiment 1, embodiment 8 ~ 11 formula 2) of table 5 gelator
The composite sensory evaluation (solvent is essence) in Margarita powder (embodiment 12 ~ 14 formula 2) of table 6 gelator
Above embodiment is only the more representational example of the present invention.Obviously, technical scheme of the present invention is not limited to above-described embodiment, can also have many changes.The change that those of ordinary skill in the art directly derives from content disclosed by the invention, all should think protection scope of the present invention.

Claims (10)

1. a powder filled hydrogel, is characterized in that described powder filled hydrogel is made up of the raw material of following quality proportioning: powder body 0.5 part, gelator 0.05 ~ 0.5 part, solvent 5 ~ 20 parts;
Described powder body comprises Plant Powder used for cosmetic, Margarita powder and inorganic particulate used for cosmetic;
Described gelator is one or both and above mixing in sodium polyacrylate, sodium carboxymethyl cellulose, Carboxymethyl cellulose sodium, acrylic copolymer, sodium alginate, carbomer;
Described solvent is deionized water or essence used for cosmetic.
2. powder filled hydrogel as claimed in claim 1, is characterized in that described diameter of particle is 2000 ~ 3000 orders.
3. powder filled hydrogel as claimed in claim 2, is characterized in that described powder body is the one in Margarita powder, Flos Rosae Rugosae powder, Aloe powder, Radix Angelicae Dahuricae powder, Poria powder, nano-calcium carbonate or nano silicon.
4. powder filled hydrogel as claimed in claim 1, is characterized in that described gelator is one of following: sodium polyacrylate, sodium carboxymethyl cellulose, Carboxymethyl cellulose sodium, acrylic copolymer, sodium alginate.
5. powder filled hydrogel as claimed in claim 1, is characterized in that described gelator is one of following: (1) sodium alginate mixes with carbomer mass ratio 2:1's; (2) the mixing of sodium alginate and carbomer mass ratio 2:1; (3) the mixing of sodium alginate and sodium polyacrylate mass ratio 2:1.
6. powder filled hydrogel as claimed in claim 1, is characterized in that described powder filled hydrogel is made up of the raw material of following quality proportioning: powder body 0.5 part, gelator 0.1 ~ 0.3 part, solvent 10 parts.
7. powder filled hydrogel as claimed in claim 1, is characterized in that described essence quality group becomes: deionized water 76.8 parts, glycerol 6 parts, propylene glycol 10 parts, polyacrylic acid 3 parts, MEIGUI CHUNLU 0.2 part and amino acid humectant 4 parts.
8. a preparation method for powder filled hydrogel described in claim 1, is characterized in that described method is: by formula ratio, powder body dissolution with solvents is made suspension, stirs, add gelator, and ultrasonic disperse is even, obtains powder filled hydrogel.
9. apply as claimed in claim 7, it is characterized in that described supersonic frequency is 40KHz, ultrasonic time 10 ~ 30min.
10. described in a claim 1, the application in cosmetic emulsion prepared by powder filled hydrogel.
CN201511002826.2A 2015-12-28 2015-12-28 A kind of powder filled hydrogel and its preparation and application Active CN105496798B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201511002826.2A CN105496798B (en) 2015-12-28 2015-12-28 A kind of powder filled hydrogel and its preparation and application

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201511002826.2A CN105496798B (en) 2015-12-28 2015-12-28 A kind of powder filled hydrogel and its preparation and application

Publications (2)

Publication Number Publication Date
CN105496798A true CN105496798A (en) 2016-04-20
CN105496798B CN105496798B (en) 2018-11-13

Family

ID=55705366

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201511002826.2A Active CN105496798B (en) 2015-12-28 2015-12-28 A kind of powder filled hydrogel and its preparation and application

Country Status (1)

Country Link
CN (1) CN105496798B (en)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106939134A (en) * 2017-03-20 2017-07-11 浙江工业大学 A kind of ink paste based on Supramolecular self assembly gel and preparation method thereof
CN115645601A (en) * 2022-10-28 2023-01-31 浙江医鼎医用敷料有限公司 Gradient-structure antibacterial hydrogel dressing and preparation method and application thereof
CN117942269A (en) * 2024-01-19 2024-04-30 义乌市东方仙子化妆品有限公司 Cosmetic powder and preparation process thereof

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101757035A (en) * 2009-11-20 2010-06-30 天津兆阳纳米科技有限公司 Preparation method of stable nanometer pearl dispersion liquid
KR20110009481A (en) * 2009-07-22 2011-01-28 (주) 제이티 Phase change hidrogel including pulp
CN102670415A (en) * 2012-04-20 2012-09-19 费兰克·K·高 Nano fiber paper mask
CN103405374A (en) * 2013-07-16 2013-11-27 福建农林大学 Freckle-removing and skin-whitening type gulcomannan particle facial mask and preparation method thereof
CN104490626A (en) * 2015-01-19 2015-04-08 董庆国 Dry powder gel face mask formula
WO2015116890A1 (en) * 2014-01-31 2015-08-06 Avent, Inc. Hydrogel matrix having a non-uniform distribution of oxygen containing cells

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20110009481A (en) * 2009-07-22 2011-01-28 (주) 제이티 Phase change hidrogel including pulp
CN101757035A (en) * 2009-11-20 2010-06-30 天津兆阳纳米科技有限公司 Preparation method of stable nanometer pearl dispersion liquid
CN102670415A (en) * 2012-04-20 2012-09-19 费兰克·K·高 Nano fiber paper mask
CN103405374A (en) * 2013-07-16 2013-11-27 福建农林大学 Freckle-removing and skin-whitening type gulcomannan particle facial mask and preparation method thereof
WO2015116890A1 (en) * 2014-01-31 2015-08-06 Avent, Inc. Hydrogel matrix having a non-uniform distribution of oxygen containing cells
CN104490626A (en) * 2015-01-19 2015-04-08 董庆国 Dry powder gel face mask formula

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
XU JIANMING ET.AL。: "Dendritic Gelators Self-Assembly in Different Solvents", 《RARE METAL MATERIALS AND ENGINEERING》 *

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106939134A (en) * 2017-03-20 2017-07-11 浙江工业大学 A kind of ink paste based on Supramolecular self assembly gel and preparation method thereof
CN115645601A (en) * 2022-10-28 2023-01-31 浙江医鼎医用敷料有限公司 Gradient-structure antibacterial hydrogel dressing and preparation method and application thereof
CN117942269A (en) * 2024-01-19 2024-04-30 义乌市东方仙子化妆品有限公司 Cosmetic powder and preparation process thereof

Also Published As

Publication number Publication date
CN105496798B (en) 2018-11-13

Similar Documents

Publication Publication Date Title
CN102525870A (en) Traditional Chinese medicine beauty mask
CN101695472B (en) Facial mask powder added with pearl powder
CN102266445A (en) Eye protection Chinese medicinal composition with health care and treatment effects
CN104224683A (en) Natural plant skin care product for improving skin metabolism of yellow race and delaying senescence
CN102210637A (en) Cosmetic containing binchotan and traditional Chinese medicinal components for skin cleaning, caring and liquid washing
CN106176450A (en) A kind of plant biological source nanospray nursing eye glue and preparation method thereof
CN105496798A (en) Powder-filled hydrogel and preparing method and application thereof
CN107669617A (en) The tender skin cosmetics of natural anti-wrinkle
CN110755307A (en) Salt lake black mud active mask and preparation method thereof
CN102091007A (en) Traditional Chinese medicine face applying mud
CN105496830A (en) Preparation method of alpinia japonica extract and application thereof in personal care products
CN109010220B (en) Cosmetic composition and preparation method thereof
CN103142440A (en) Medlar health-care shampoo
CN107898749A (en) A kind of topical composition with skin-care effect and preparation method thereof
CN1528263A (en) Beauty face mask of chinese medicine and use method thereof
CN108703918A (en) It is a kind of to have effects that anti-dandruff shampoo and preparation method thereof
CN105616307A (en) Yogurt facial mask and preparation method thereof
CN104083313A (en) Facial mask capable of whitening, lightening spots and tendering skin
CN101112356A (en) Traditional Chinese medicine mask
CN103315925A (en) Chinese medicine facial mask possessing whitening and moisturizing efficacy, and preparation method thereof
CN109602653B (en) Composition, cosmetic and essence with whitening effect and preparation method thereof
CN102293940B (en) Oral liquid for beautifying
CN105106085A (en) Chinese medicinal herb sunscreen cream containing attapulgite
CN104758214A (en) Pure natural freckle-removing facial mask
CN104188847A (en) Non-silicone-oil plant anti-allergic shampoo

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant