CN105477137A - 一种治疗脊髓损伤的中药汤剂 - Google Patents
一种治疗脊髓损伤的中药汤剂 Download PDFInfo
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Abstract
本发明公开了一种治疗脊髓损伤的中药汤剂,其是由以下重量份的中药原料制成:辛夷10、苍耳子10、佛手12、小蓟9、杜仲5、紫菀8、海藻12、络石藤12、金银花6、龙胆草7、使君子8、紫苏梗15、透骨草15、七叶一枝花15、乌梢蛇12、西河柳15、木通15、荆芥穗3、延胡索15、火麻仁16、徐长卿6、石韦10、忍冬藤15、地龙5、骨碎补7、博落回12、大血藤9、地榆炭10、白头翁7、附片9、荜澄茄8、合欢皮5、红藤10、乌药8、附子9、僵蚕10、全蝎10。本发明各原料药经辨证配伍,共奏散瘀止痛、通经活络、补肾强骨、舒筋活血之功效,对脊髓损伤疗效显著,值得临床上进一步推广使用。
Description
技术领域
本发明涉及一种治疗脊髓损伤的中药汤剂,属于中药领域。
背景技术
脊髓损伤是指由于外界直接或间接因素导致脊髓损伤,在损害的相应节段出现各种运动、感觉和括约肌功能障碍,肌张力异常及病理反射等的相应改变。脊髓损伤的程度和临床表现取决于原发性损伤的部位和性质。现阶段西医对本病尚无有效药物。处理方法仅限于对症治疗。如手术治疗或注射皮质类固醇和神经节苷脂等药物。患者创伤大,并且很容易引起并发症,不能达到治疗的目的。
发明内容
本发明的目的在于提供一种治疗脊髓损伤的中药汤剂。
本发明所采用的技术解决方案是:
一种治疗脊髓损伤的中药汤剂,其是由以下重量份的中药原料制成:辛夷4-13、苍耳子5-11、佛手9-14、小蓟7-18、杜仲2-15、紫菀6-17、海藻7-14、络石藤10-15、金银花5-10、龙胆草5-10、使君子5-10、紫苏梗10-20、透骨草10-20、七叶一枝花10-20、乌梢蛇10-20、西河柳10-20、木通10-20、荆芥穗3-5、延胡索10-20、火麻仁10-20、徐长卿5-10、石韦7-16、忍冬藤10-20、地龙3-10、骨碎补5-15、博落回10-15、大血藤5-15、地榆炭8-15、白头翁5-10、附片7-11、荜澄茄6-14、合欢皮3-17、红藤6-18、乌药5-17、附子5-16、僵蚕6-17、全蝎7-14。
优选的,各原料药的重量份配比为:辛夷10、苍耳子10、佛手12、小蓟9、杜仲5、紫菀8、海藻12、络石藤12、金银花6、龙胆草7、使君子8、紫苏梗15、透骨草15、七叶一枝花15、乌梢蛇12、西河柳15、木通15、荆芥穗3、延胡索15、火麻仁16、徐长卿6、石韦10、忍冬藤15、地龙5、骨碎补7、博落回12、大血藤9、地榆炭10、白头翁7、附片9、荜澄茄8、合欢皮5、红藤10、乌药8、附子9、僵蚕10、全蝎10。
上述中药汤剂的制备方法如下:
(1)按照上述重量份配比将辛夷、苍耳子、佛手、小蓟、杜仲、紫菀、海藻、络石藤、金银花、龙胆草、使君子、紫苏梗、透骨草、七叶一枝花、乌梢蛇、西河柳、木通、荆芥穗、延胡索、火麻仁、徐长卿、石韦、忍冬藤、地龙、骨碎补、博落回、大血藤、地榆炭、白头翁、附片、荜澄茄、合欢皮、红藤、乌药、附子、僵蚕、全蝎混合均匀得到混合物,将该混合物与水按照重量比1:8的比例混合,在水中浸泡60分钟。
(2)将所述步骤(1)中的混合物及水煎煮120分钟后,过滤得到第一滤液及滤渣。
(3)将所述步骤(2)中所得滤渣与水按照重量比1:6的比例混合,再煎煮100分钟,然后过滤得到第二滤液及滤渣,将第一滤液与第二滤液混合,获得药物的汤剂。
本发明的药理及有益效果如下:
脊髓损伤在中医学属外伤瘀血所致"腰痛"、"痿证"、"癃闭"等病证范畴。本发明有针对性的选取辛夷、苍耳子、佛手、小蓟、杜仲、紫菀、海藻、络石藤、金银花、龙胆草、使君子、紫苏梗、透骨草、七叶一枝花、乌梢蛇、西河柳、木通、荆芥穗、延胡索、火麻仁、徐长卿、石韦、忍冬藤、地龙、骨碎补、博落回、大血藤、地榆炭、白头翁、附片、荜澄茄、合欢皮、红藤、乌药、附子、僵蚕、全蝎共37味中药原料熬制成中药汤剂。
其中:辛夷,散风寒,通鼻窍。
苍耳子,散风除湿、通窍止痛。
佛手,舒肝理气,和胃止痛。
小蓟,凉血止血,活血解毒。
杜仲,具补肝肾、强筋骨、降血压、安胎等诸多功效。
紫菀,润肺下气;化痰止咳。
海藻,清热、软坚散结、软坚、消痰、利水退肿。
络石藤,祛风通络、凉血消肿。
金银花,清热解毒。
龙胆草,清热燥湿,泻肝定惊。
使君子,消积、健脾,杀虫通便。
紫苏梗,行气和中。
透骨草,祛风除湿、舒筋活络、活血止痛、解毒化疹。
七叶一枝花,具有清热解毒,消肿止痛的功效。
乌梢蛇,祛风湿,通经络,熄风止痉,止痒解毒。
西河柳,有疏风、解表、透疹、解毒的功效。
木通,利水、清热、通乳。
荆芥穗,性辛,微温,归肺、肝经,有解表散风,透疹的功效。
延胡索,活血;散瘀;理气;止痛。
火麻仁,润肠通便、润燥杀虫。
徐长卿,祛风化湿,止痛止痒。
石韦,利尿通淋,清热止血。
忍冬藤,具有清热解毒,疏风通络的疗效。
地龙,具有清热定惊,痛经活络的功效。
骨碎补,补肾强骨;活血止痛。
博落回,祛风解毒,行气消肿,杀虫。
大血藤,具有清热解毒,活血通络,祛风止痉的作用。
地榆炭,凉血止血,解毒敛疮。
白头翁,有清热解毒、凉血止痢、燥湿杀虫的功效。
附片,温补脾肾,散寒止痛。
荜澄茄,祛风散寒、理气止痛。
合欢皮,解郁,和血,宁心,消痈肿。
红藤,通经活络、散瘀止痛、理气行血、杀虫。
乌药,行气止痛,温肾散寒。
附子,回阳救逆,补火助阳,散寒止痛。
僵蚕,祛风解痉,化痰散结。
全蝎,祛风止痉;通络止痛。
全方配伍,共奏散瘀止痛、通经活络、补肾强骨、舒筋活血之功效,对脊髓损伤疗效显著,值得临床上进一步推广使用。
临床资料
1、病例选择:
选择确诊的脊髓损伤患者196例临床观察,病人随机分成治疗组和对照组两组,治疗组100例,其中男性47例,女性53例,年龄28~61岁,平均病程2年;对照组96例,其中男性46例,女性50例,年龄27~60岁,平均病程2年。治疗组和对照组两组病例的病程、症状轻重程度基本一致,无显著差异,具有可比性。
2、药物选择:
治疗组服用本发明中药汤剂,每日1剂,分早晚服用;12天为1个疗程,3~4个疗程即可痊愈,病情严重者遵医嘱酌增用量。
对照组服用盐酸替扎尼定片,病人初次使用宜有2~4周的剂量调整期。开始用量每次2~4mg,6~8小时1次,因本品口服有较强的首过效应,使用时应注意剂量个体化。
3、疗效判定:
(1)治愈:主要症状全部消失,身体恢复如常。
(2)显效:主要症状明显缓解,身体明显好转。
(3)有效:主要症状有所缓解,身体好有所转。
(4)无效:通过治疗后主要症状无减轻或加重。
4、结果:
选用本发明中药汤剂的治疗组中,治愈62例,显效22例,有效15例,无效1例,治愈率62%,总有效率99%。
对照组中治愈28例,显效12例,有效20例,无效36例,治愈率29.2%,总有效率62.5%。
治疗结果显示,治疗组的治愈率和总有效率均明显高于对照组。
典型病例
宋某,男,23岁。体操运动员,在项目训练中造成脊髓损伤,医院确诊。受损部位以下有知觉,但不能站立,不能独立翻身疼痛。服用西药,有所缓解,但效果不明显。使用本发明药物1个疗程后,疼痛症状减轻,可以自主翻身。使用2个疗程后,疼痛完全消失,可以辅助站立。使用3个疗程后,可以独立站立,损伤部位完全恢复。使用至今,未出现复发症状。现已经可以完全正常生活。
具体实施方式
实施例1
按下述重量份配比称取各中药原料:
辛夷10、苍耳子10、佛手12、小蓟9、杜仲5、紫菀8、海藻12、络石藤12、金银花6、龙胆草7、使君子8、紫苏梗15、透骨草15、七叶一枝花15、乌梢蛇12、西河柳15、木通15、荆芥穗3、延胡索15、火麻仁16、徐长卿6、石韦10、忍冬藤15、地龙5、骨碎补7、博落回12、大血藤9、地榆炭10、白头翁7、附片9、荜澄茄8、合欢皮5、红藤10、乌药8、附子9、僵蚕10、全蝎10。
制备方法如下:
(1)按照上述重量份配比将辛夷、苍耳子、佛手、小蓟、杜仲、紫菀、海藻、络石藤、金银花、龙胆草、使君子、紫苏梗、透骨草、七叶一枝花、乌梢蛇、西河柳、木通、荆芥穗、延胡索、火麻仁、徐长卿、石韦、忍冬藤、地龙、骨碎补、博落回、大血藤、地榆炭、白头翁、附片、荜澄茄、合欢皮、红藤、乌药、附子、僵蚕、全蝎混合均匀得到混合物,将该混合物与水按照重量比1:8的比例混合,在水中浸泡60分钟。
(2)将所述步骤(1)中的混合物及水煎煮120分钟后,过滤得到第一滤液及滤渣。
(3)将所述步骤(2)中所得滤渣与水按照重量比1:6的比例混合,再煎煮100分钟,然后过滤得到第二滤液及滤渣,将第一滤液与第二滤液混合,获得药物的汤剂。
实施例2
按下述重量份配比称取各中药原料:
辛夷4、苍耳子11、佛手9、小蓟18、杜仲2、紫菀6、海藻7、络石藤15、金银花10、龙胆草5、使君子10、紫苏梗10、透骨草20、七叶一枝花10、乌梢蛇10、西河柳20、木通10、荆芥穗3、延胡索20、火麻仁10、徐长卿5、石韦16、忍冬藤10、地龙10、骨碎补5、博落回10、大血藤15、地榆炭8、白头翁5、附片11、荜澄茄14、合欢皮3、红藤6、乌药5、附子16、僵蚕17、全蝎7。
制备方法同实施例1。
实施例3
按下述重量份配比称取各中药原料:
一种治疗脊髓损伤的中药汤剂,其是由以下重量份的中药原料制成:辛夷13、苍耳子5、佛手14、小蓟7、杜仲15、紫菀17、海藻14、络石藤10、金银花5、龙胆草10、使君子5、紫苏梗20、透骨草10、七叶一枝花20、乌梢蛇20、西河柳10、木通20、荆芥穗5、延胡索10、火麻仁20、徐长卿10、石韦7、忍冬藤20、地龙3、骨碎补15、博落回15、大血藤5、地榆炭15、白头翁10、附片7、荜澄茄6、合欢皮17、红藤18、乌药17、附子5、僵蚕6、全蝎14。
制备方法同实施例1。
Claims (2)
1.一种治疗脊髓损伤的中药汤剂,其特征在于它是由以下重量份的中药原料制成:辛夷4-13、苍耳子5-11、佛手9-14、小蓟7-18、杜仲2-15、紫菀6-17、海藻7-14、络石藤10-15、金银花5-10、龙胆草5-10、使君子5-10、紫苏梗10-20、透骨草10-20、七叶一枝花10-20、乌梢蛇10-20、西河柳10-20、木通10-20、荆芥穗3-5、延胡索10-20、火麻仁10-20、徐长卿5-10、石韦7-16、忍冬藤10-20、地龙3-10、骨碎补5-15、博落回10-15、大血藤5-15、地榆炭8-15、白头翁5-10、附片7-11、荜澄茄6-14、合欢皮3-17、红藤6-18、乌药5-17、附子5-16、僵蚕6-17、全蝎7-14。
2.根据权利要求1所述的一种治疗脊髓损伤的中药汤剂,其特征在于各中药原料的重量份为:辛夷10、苍耳子10、佛手12、小蓟9、杜仲5、紫菀8、海藻12、络石藤12、金银花6、龙胆草7、使君子8、紫苏梗15、透骨草15、七叶一枝花15、乌梢蛇12、西河柳15、木通15、荆芥穗3、延胡索15、火麻仁16、徐长卿6、石韦10、忍冬藤15、地龙5、骨碎补7、博落回12、大血藤9、地榆炭10、白头翁7、附片9、荜澄茄8、合欢皮5、红藤10、乌药8、附子9、僵蚕10、全蝎10。
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