CN105456875A - Traditional Chinese medicine composition for treating skin itch - Google Patents

Traditional Chinese medicine composition for treating skin itch Download PDF

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Publication number
CN105456875A
CN105456875A CN201511023075.2A CN201511023075A CN105456875A CN 105456875 A CN105456875 A CN 105456875A CN 201511023075 A CN201511023075 A CN 201511023075A CN 105456875 A CN105456875 A CN 105456875A
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medicine composition
chinese medicine
composition
skin itch
pruritus
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CN201511023075.2A
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郭小宁
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Individual
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/30—Boraginaceae (Borage family), e.g. comfrey, lungwort or forget-me-not
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/13—Coniferophyta (gymnosperms)
    • A61K36/15—Pinaceae (Pine family), e.g. pine or cedar
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/234—Cnidium (snowparsley)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284—Atractylodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286—Carthamus (distaff thistle)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/34—Campanulaceae (Bellflower family)
    • A61K36/342—Adenophora
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/42—Cucurbitaceae (Cucumber family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/47—Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/58—Meliaceae (Chinaberry or Mahogany family), e.g. Azadirachta (neem)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/69—Polygalaceae (Milkwort family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
    • A61K36/725—Ziziphus, e.g. jujube
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/752—Citrus, e.g. lime, orange or lemon
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/83—Thymelaeaceae (Mezereum family), e.g. leatherwood or false ohelo
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/889—Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8969—Polygonatum (Solomon's seal)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A61K36/9062—Alpinia, e.g. red ginger or galangal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10—Preparation or pretreatment of starting material
    • A61K2236/19—Preparation or pretreatment of starting material involving fermentation using yeast, bacteria or both; enzymatic treatment

Abstract

The invention discloses a traditional Chinese medicine composition for treating skin itch. The composition is prepared from 23 raw material medicines including lithospermum erythrorhizon, Angelica dahurica, common cnidium fruit, safflowers, medicated leaven, polygonatum odoratum, Adenophora trachelioides Maxim., stellera chamaejasme, lycorisradiata, Chinense golden larch bark, Hainan chaulmoogra seeds and the like. Auxiliary materials are added according to the conventional process to be prepared into clinically-accepted capsules, tables, pills, granules, oral liquid, emplastrum, ointment, spray, ointment or tincture. The medicine composition has the functions of improving immunity of human bodies, improving circulatory disturbance and recovering functions of human bodies. The traditional Chinese medicine composition is low in cost, good in skin itch treatment effect, quick in effect, short in treatment course, small in side effect, low in relapse rate and suitable for treating vaiour skin itch patients.

Description

A kind of Chinese medicine composition for the treatment of skin pruritus
Technical field
The present invention relates to a kind of pharmaceutical composition, particularly relate to a kind of Chinese medicine composition for the treatment of skin pruritus.
Background technology
Pruritus is one of common clinically dermatosis, is especially more common in old people.It is characterized by based on pruritus, and without primary lesion.Locality and general two kinds can be divided into clinically.Pruritus is a kind of conscious pruritus and clinically without the dermatosis of primary lesion.Locality pruritus is common in anus, pudendum or extremity etc., local only conscious pruritus, and there is no erythra, with the passing of time can cause pachyderma, eczema sample changes.Anal canal and perianal obstinate pruritus are the cardinal symptoms of primary disease, from the beginning of time be generally limited to skin around the rectum pruritus, mostly be paroxysmal, the degree weight of pruritus differs, as do not healed for a long time, what have spreads to scrotum or labia, and between especially stitching before and after perineal position, pruritus more very, night is more remarkable, sometimes as worm climb, ant walks; Sometimes as mosquito bite, baking, make people be difficult to fall asleep, feel restless, be out of patience.General pruritus systemic all has the sensation of itching everywhere, but is not that whole body is itched simultaneously, often moves on to another place by one.The degree of itching is not quite similar, although there is people to feel, skin is itched, but still can stand, and some patients think that whole body is very itched, need with ferrum brush brush skin or hot water laundering, until dermatorrhagia and feels pain and causalgia time, tickle and itch just temporarily alleviates.Often to itch night heavily, patient has a sleepless night because itching or can not be sleeping.Due to violent pruritus, constantly scratch, scratching of scratch, blood crusts or strip can be occurred, sometimes have eczema sample to change, lichenification or pigmentation.The skin of scratching also easily infects and furuncle and phyma or folliculitis occurs.The treatment of locality or general pruritus, also has many Therapeutic Method clinically, by oral all kinds of Chinese and western drugs or external use anti pruritic agent, pruritus all can be made to alleviate and be cured.But wherein about there is the pruritus patient of 20 ~ 30% for intractable pruritus.Can prolongedly not heal and recurrent exerbation after using medicine, and treatment cost is high, using method is complicated.
Summary of the invention
The object of the invention is to provide a kind of Chinese medicine composition for the treatment of skin pruritus.
The present invention is achieved through the following technical solutions:
The crude drug of Chinese medicine composition of the present invention consists of:
The crude drug composition of Chinese medicine composition of the present invention is preferably:
The crude drug composition of Chinese medicine composition of the present invention is preferably:
The crude drug composition of Chinese medicine composition of the present invention is preferably:
Chinese medicine composition of the present invention conveniently technique adds customary adjuvant and makes the capsule of clinical acceptance, tablet, pill, granule, oral liquid, emplastrum, ointment, spray, liniment or tincture.
Pharmaceutical composition of the present invention has raising immunity of organisms, improves circulatory disturbance, recovers function of human body.The present composition is effective to skin pruritus such as treatment dermatitis, skin allergy, senile skin pruritus, silver bits, and instant effect, short treating period, side effect is little, and relapse rate is low, is applicable to all kinds of skin pruritus patient treatment.
Experimental example is used for further illustrating the present invention below, but is not limited to the present invention.
Experimental example one: clinical trial
1, clinical experiment:
Skin pruritus patient 400 example is made a definite diagnosis in selection, age 21-55 year between, the mean age is 35.3 years old, and the course of disease is the shortest be half a year, and the longest is 5 years, average out to 2.19, is divided into 4 groups at random, test group 1,2,3 each 100 examples, matched group 100 is routine.
2, Therapeutic Method:
Test group 1 oral ' Yanming ' capsules for clearing (according to the preparation of embodiment 1 method), every twice-daily, each 2,0.3g/ grain; It within 7 days, is 1 course for the treatment of.
Test group 2 external ointment of the present invention (according to the preparation of embodiment 2 method), every day is used for skin pruritus place sooner or later; It within 7 days, is 1 course for the treatment of.
The oral Tablets of test group 3 (according to the preparation of embodiment 3 method), every twice-daily, each 2,0.3g/ sheet; It within 7 days, is 1 course for the treatment of.
The oral Chlorate of matched group, 3 times on the one, each 1,0.4g/ sheet 7 days was 1 course for the treatment of.
Above four groups at treatments period, the pungent stimulation foods such as fasting wine, seafood.
3, diagnostic criteria: the diagnostic criteria meeting " clinical dermatology " pruritus, exclusion standard: the 1. pruritus that causes of the viscera disease such as diabetes, chronic hepatopathy, chronic nephropathy, renal failure, internal tumor, autoimmune disease; 2. the immunosuppressant such as Radix Tripterygii Wilfordii are taken in 4 weeks; 3. corticosteroid hormone was taken in 1 week; 4. medicine or food anaphylaxis history person is had.
4, criterion of therapeutical effect:
Recovery from illness: skin pruritus symptom is all eliminated;
Effective: the degree of skin pruritus takes a turn for the better 75% ~ 90%;
Effective: the degree of skin pruritus takes a turn for the better 35% ~ 75%;
Invalid: the degree of skin pruritus is not improved.
5, therapeutic outcome:
Group Recovery from illness (example) Effective (example) Effectively (example) Invalid (example) Total effective rate
Experimental group 1 65 22 12 1 99％
Experimental group 2 58 32 8 2 98％
Experimental group 3 64 25 10 1 99％
Matched group 32 35 13 20 80％
300 routine patients of test group 1,2,3, after treating 2 courses for the treatment of, total effective rate reaches more than 98%, 100 routine patients of matched group, and after treating 2 courses for the treatment of, total effective rate is 80%; The total effective rate of test group 1,2,3 compares with the total effective rate of matched group that there were significant differences.In addition, visible in clinical observation, the patient in experimental group 1,2,3 finds no toxic and side effects or allergic phenomena in use invention medicine, is the good medicine for the treatment of skin pruritus, is worthy of popularization.
Following embodiment all can realize the effect of above-mentioned experimental example.
Detailed description of the invention
embodiment 1 capsule
Said medicine conveniently technique adds customary adjuvant and makes capsule, 0.3g/ grain, a twice-daily, one time 2.
embodiment 2 ointment
Said medicine conveniently technique adds customary adjuvant and makes ointment.15g/ props up, and every day, secondary was applied to skin pruritus place sooner or later.
embodiment 3 tablet
Said medicine conveniently technique adds customary adjuvant and makes tablet.0.3g/ sheet, every twice-daily, each two.
Embodiment 4 spray
Said medicine conveniently technique adds customary adjuvant and makes spray, and every day, secondary was sprayed on skin pruritus place sooner or later.
Embodiment 5 granule
Said medicine conveniently technique adds customary adjuvant and makes granule.10g/ bag, every twice-daily, each 1 bag.
embodiment 6 liniment
Said medicine conveniently technique adds customary adjuvant and makes liniment, and every day, secondary was wiped in skin pruritus place sooner or later.

Claims (6)

1. treat a Chinese medicine composition for skin pruritus, it is characterized in that, the crude drug of said composition consists of:
2. Chinese medicine composition as claimed in claim 1, is characterized in that the crude drug of said composition consists of:
3. Chinese medicine composition as claimed in claim 1, is characterized in that the crude drug of said composition consists of:
4. Chinese medicine composition as claimed in claim 1, is characterized in that the crude drug of said composition consists of:
5. the Chinese medicine composition as described in one of claim 1-4, it is characterized in that said composition conveniently technique add customary adjuvant and make the capsule of clinical acceptance, tablet, pill, granule, oral liquid, emplastrum, ointment, spray, liniment or tincture.
6. the application of the Chinese medicine composition as described in one of claim 1-4 in the medicine of preparation treatment skin pruritus.
CN201511023075.2A 2015-12-27 2015-12-27 Traditional Chinese medicine composition for treating skin itch Pending CN105456875A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
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Application Number Priority Date Filing Date Title
CN201511023075.2A CN105456875A (en) 2015-12-27 2015-12-27 Traditional Chinese medicine composition for treating skin itch

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Publication Number Publication Date
CN105456875A true CN105456875A (en) 2016-04-06

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103394002A (en) * 2013-07-05 2013-11-20 李青平 Medicinal composition for treating cutaneous pruritus as well as preparation method and application thereof
CN103566258A (en) * 2013-11-08 2014-02-12 安徽工贸职业技术学院 Traditional Chinese medicine lotion for treating cutaneous pruritus
CN104189392A (en) * 2014-09-05 2014-12-10 杜柏荣 Traditional Chinese medicinal composition for treating skin itch and preparation method thereof
CN105168823A (en) * 2015-09-18 2015-12-23 马鞍山德宏堂生物科技有限公司 Externally applied liniment for treating cutaneous pruritus

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103394002A (en) * 2013-07-05 2013-11-20 李青平 Medicinal composition for treating cutaneous pruritus as well as preparation method and application thereof
CN103566258A (en) * 2013-11-08 2014-02-12 安徽工贸职业技术学院 Traditional Chinese medicine lotion for treating cutaneous pruritus
CN104189392A (en) * 2014-09-05 2014-12-10 杜柏荣 Traditional Chinese medicinal composition for treating skin itch and preparation method thereof
CN105168823A (en) * 2015-09-18 2015-12-23 马鞍山德宏堂生物科技有限公司 Externally applied liniment for treating cutaneous pruritus

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Application publication date: 20160406