CN104784332B - A kind of preparation method of the medicament treating Chronic Urinary Tract Infection - Google Patents
A kind of preparation method of the medicament treating Chronic Urinary Tract Infection Download PDFInfo
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- CN104784332B CN104784332B CN201510236883.0A CN201510236883A CN104784332B CN 104784332 B CN104784332 B CN 104784332B CN 201510236883 A CN201510236883 A CN 201510236883A CN 104784332 B CN104784332 B CN 104784332B
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Abstract
The preparation method that the present invention relates to a kind of medicament treating Chronic Urinary Tract Infection, the method comprises the following steps: to take Radix Inulae Pterocaulae 120 grams, 100 grams of 100 grams, ten liang leaves of mountain Pericarpium Citri Reticulatae Viride, little return from the grave 80 grams, little Radix Scorzonerae austriacae 90 grams, Radix seu Herba Pedicularis 80 grams, 70 grams of five tastes rattan, Tucrium Pilosum 60 grams, Herba Ceratopteridis Thalictroidis 50 grams, Radix seu Herba Poranae Racemosae 50 grams, Lindernia angustifolia (Benth.) Wettst. 30 grams, Herba Boenninghauseniae 30 grams, Aralia decaisneana Hance 35 grams, Chloranthus japonicusSieb. 30 grams and 20 grams of Radix Glycyrrhizae, add 15000 milliliters of water, the heating 5 hours when backflow, filter, make filtrate be cooled to room temperature, to obtain final product.The medicament for the treatment of Chronic Urinary Tract Infection of the present invention clinical application find that have effect rapidly, therapeutic effect substantially, better tolerance, advantage with low cost, without any side effects.
Description
Technical field
The present invention relates to field of medicaments, specifically, the preparation method relating to a kind of medicament treating Chronic Urinary Tract Infection.
Background technology
Chronic Urinary Tract Infection is a kind of commonly encountered diseases, it is common that caused by up infection, delays with the passing of time, recurrent exerbation, often sends out because of overstrain or diseases caused by exogenous pathogenic factor.Primary disease is apt to occur in Women of childbearing age, and M-F is about 1: 8.The symptom of Chronic Urinary Tract Infection does not have acute urinary tract infection so notable, shows as frequent micturition, urgent micturition, dysurea, so that dysuria, urethral secretions reduces, or only has pruritus or ant row sense, and stimulation disease of urinating is notable unlike acute stage, and some patients can be asymptomatic.Chronic Urinary Tract Infection is relatively difficult to thoroughly radical cure, orthobiosis is not affected owing to urinary tract infection symptom is many, feel it is indisposition, such time one is of a specified duration, reform into Chronic Urinary Tract Infection, at this moment many complication are arisen that, as male can concurrently orchitis, epididymitis, prostatitis, seminal vesiculitis, Epididymis disease etc..Women can concurrently vaginitis, cervicitis, adnexitis, endometritis, pelvic inflammatory disease etc., chronic and repeated infection person may result in renal damage.Bring double burden usually to the economy of patient and spirit.
At present, clinical treatment Chronic Urinary Tract Infection mainly applies antibacterials, as ofloxacin adds metronidazole；Or ceftriaxone adds metronidazole and adds azithromycin etc., the course for the treatment of is long, and costly, side effect is relatively larger.Prolonged and repeated author, systemic administration DeGrain, and Drug abuse easily make antibacterial produce drug resistance.And treatment by Chinese herbs primary disease to have toxic reaction little, the advantage for the treatment of both the principal and secondary aspects of a disease, symptom can be improved, recurrence can be reduced again.
Summary of the invention
The preparation method that it is an object of the invention to provide a kind of medicament treating Chronic Urinary Tract Infection.
In order to realize the purpose of the present invention, the preparation method that the present invention provides a kind of medicament treating Chronic Urinary Tract Infection, the method comprises the following steps: to take Radix Inulae Pterocaulae 120 grams, 100 grams of 100 grams, ten liang leaves of mountain Pericarpium Citri Reticulatae Viride, little return from the grave 80 grams, little Radix Scorzonerae austriacae 90 grams, Radix seu Herba Pedicularis 80 grams, 70 grams of five tastes rattan, Tucrium Pilosum 60 grams, Herba Ceratopteridis Thalictroidis 50 grams, Radix seu Herba Poranae Racemosae 50 grams, Lindernia angustifolia (Benth.) Wettst. 30 grams, Herba Boenninghauseniae 30 grams, Aralia decaisneana Hance 35 grams, Chloranthus japonicusSieb. 30 grams and 20 grams of Radix Glycyrrhizae, add 15000 milliliters of water, the heating 5 hours when backflow, filter, make filtrate be cooled to room temperature, to obtain final product.
The present invention also provides for compositions purposes in the medicament of preparation treatment Chronic Urinary Tract Infection, and described medicament is made up by weight of following bulk drugs: Radix Inulae Pterocaulae 120 parts, 100 parts of 100 parts, ten liang leaves of mountain Pericarpium Citri Reticulatae Viride, little return from the grave 80 parts, little Radix Scorzonerae austriacae 90 parts, Radix seu Herba Pedicularis 80 parts, 70 parts of five tastes rattan, Tucrium Pilosum 60 parts, Herba Ceratopteridis Thalictroidis 50 parts, Radix seu Herba Poranae Racemosae 50 parts, Lindernia angustifolia (Benth.) Wettst. 30 parts, Herba Boenninghauseniae 30 parts, Aralia decaisneana Hance 35 parts, Chloranthus japonicusSieb. 30 parts and 20 parts of Radix Glycyrrhizae.
Preferably, described medicament can be tablet, dispersible tablet, rapidly dissolving tablet, decoction or granule.
In the present compositions, Radix Inulae Pterocaulae, mountain Pericarpium Citri Reticulatae Viride are monarch drug, ten liang of leaves, little return from the grave, little Radix Scorzonerae austriacae, Radix seu Herba Pedicularis, five tastes rattan are ministerial drug, Tucrium Pilosum, Herba Ceratopteridis Thalictroidis, Radix seu Herba Poranae Racemosae, Lindernia angustifolia (Benth.) Wettst., Herba Boenninghauseniae, Aralia decaisneana Hance, Chloranthus japonicusSieb. are adjuvant drug, and Radix Glycyrrhizae is for making medicine.
The medicament for the treatment of Chronic Urinary Tract Infection of the present invention uses natural drug, clinical application find that, have effect rapidly, therapeutic effect substantially, better tolerance, advantage with low cost, without any side effects.
Detailed description of the invention
Below by way of the description of detailed description of the invention, the invention will be further described, but this is not limitation of the present invention, those skilled in the art's basic thought according to the present invention, various modifications may be made or improves, but without departing from the basic thought of the present invention, all within the scope of the present invention.
The preparation of embodiment decoction of the present invention
Take Radix Inulae Pterocaulae 120 grams, 100 grams of 100 grams, ten liang leaves of mountain Pericarpium Citri Reticulatae Viride, little return from the grave 80 grams, little Radix Scorzonerae austriacae 90 grams, Radix seu Herba Pedicularis 80 grams, 70 grams of five tastes rattan, Tucrium Pilosum 60 grams, Herba Ceratopteridis Thalictroidis 50 grams, Radix seu Herba Poranae Racemosae 50 grams, Lindernia angustifolia (Benth.) Wettst. 30 grams, Herba Boenninghauseniae 30 grams, Aralia decaisneana Hance 35 grams, Chloranthus japonicusSieb. 30 grams and 20 grams of Radix Glycyrrhizae, add 15000 milliliters of water, the heating 5 hours when backflow, filter, make filtrate be cooled to room temperature, to obtain final product.
Experimental example
Diagnostic criteria
According to " practical internal medicine " (Chen Haozhu. practical internal medicine [M] .12 version. Beijing: People's Health Publisher, 2005:2217.) formulate the diagnostic criteria of Chronic Urinary Tract Infection.Chronic Urinary Tract Infection diagnostic criteria is: 1. regular CCMS (requiring that urine rests on 4～more than 6h in bladder) bacteria quantified is cultivated, clump count >=105/mL；2. the centrifugal midstream urine sediment leukocyte count of cleaning > 10/HP, or have urinary tract infection symptom person.
Choose patient 90 example meeting above-mentioned standard, wherein male 10 examples, female 80 example；29～43 years old age, average 36 years old.
The decoction prepared in embodiment is used to treat, one day 3 times, oral 100 milliliters every time, treatment 50 days continuously.
Criterion of therapeutical effect
Criterion of therapeutical effect reference " new Chinese medicine guideline of clinical investigations (tries) " (Ministry of Health of the People's Republic of China. new Chinese medicine guideline of clinical investigations (tries) [M]. Beijing: China Medical Science Press, 2002:95.) formulate.
Recovery from illness: clinical symptoms, sign disappear, and routine urianlysis 2 is subnormal, urine bacterium is negative, and urinates bacterium 1 time in check in the 2nd, 6 week, is feminine gender, for recent healing, follows the trail of 6 months without recidivist for cure completely；
Effective: clinical symptoms, sign disappear or substantially disappear, routine urinalysis is normal or close to normal, urine bacterium is negative；
Effective: clinical symptoms, sign alleviate, and routine urinalysis significantly improves, urine is cultivated occasionally has the positive；
Invalid: symptom and urine examination improve inconspicuous, and urine bacterium quantitative check is still positive, or in time within the 2nd, 6 week, checking, urine bacterium is positive, and be same strain.
Result
Through treating, it has been found that all patients clinical symptoms, sign disappear, and routine urianlysis 2 is subnormal, urine bacterium is negative, and urinates bacterium 1 time in check in the 2nd, 6 week, is feminine gender.Follow the trail of 6 months after the treatment without recidivist, therefore all meet the standard of recovery from illness.
Safety is investigated
Over the course for the treatment of patient is carried out basic vital sign monitoring, including: routine blood test, hepatic and renal function, electrocardiogram, all find no obvious exception, it was shown that the present composition is safe.
Claims (1)
1. the preparation method of the medicament treating Chronic Urinary Tract Infection, the method comprises the following steps: to take Radix Inulae Pterocaulae 120 grams, 100 grams of 100 grams, ten liang leaves of mountain Pericarpium Citri Reticulatae Viride, little return from the grave 80 grams, little Radix Scorzonerae austriacae 90 grams, Radix seu Herba Pedicularis 80 grams, 70 grams of five tastes rattan, Tucrium Pilosum 60 grams, Herba Ceratopteridis Thalictroidis 50 grams, Radix seu Herba Poranae Racemosae 50 grams, Lindernia angustifolia (Benth.) Wettst. 30 grams, Herba Boenninghauseniae 30 grams, Aralia decaisneana Hance 35 grams, Chloranthus japonicusSieb. 30 grams and 20 grams of Radix Glycyrrhizae, add 15000 milliliters of water, the heating 5 hours when backflow, filter, make filtrate be cooled to room temperature, to obtain final product.
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| CN103127411B (en) * | 2013-02-05 | 2014-04-09 | 闫佩云 | Traditional Chinese medicine used for treating urinary tract infection disease |
| CN103989984A (en) * | 2014-04-22 | 2014-08-20 | 安徽省太湖山中药饮片有限公司 | Traditional Chinese medicine composition for treating urinary tract infection |
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Inventor after: Liu Kaifeng Inventor after: Yu Hongtao Inventor before: Kong Tao |
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Effective date of registration: 20160524 Address after: 225001 No. 98 West Nantong Road, Guangling District, Jiangsu, Yangzhou Applicant after: Liu Kaifeng Applicant after: Yu Hongtao Address before: 224051 Yancheng City hope road, Jiangsu, No. 9 Applicant before: Kong Tao |
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