CN104306819B - It is a kind of to treat Chinese medicine composition of NUG and preparation method thereof - Google Patents

It is a kind of to treat Chinese medicine composition of NUG and preparation method thereof Download PDF

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CN104306819B
CN104306819B CN201410617206.9A CN201410617206A CN104306819B CN 104306819 B CN104306819 B CN 104306819B CN 201410617206 A CN201410617206 A CN 201410617206A CN 104306819 B CN104306819 B CN 104306819B
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nug
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CN104306819A (en
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全香花
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Shengyi Traditional Chinese Medicine Innovation Research Co ltd
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Affiliated Hospital of University of Qingdao
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/90Smilacaceae (Catbrier family), e.g. greenbrier or sarsaparilla
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/62Leeches; Worms, e.g. cestodes, tapeworms, nematodes, roundworms, earth worms, ascarids, filarias, hookworms, trichinella or taenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/19Acanthaceae (Acanthus family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/27Asclepiadaceae (Milkweed family), e.g. hoya
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • A61K36/355Lonicera (honeysuckle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/37Celastraceae (Staff-tree or Bittersweet family), e.g. tripterygium or spindletree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489Sophora, e.g. necklacepod or mamani
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • A61K36/744Gardenia
    • AHUMAN NECESSITIES
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/78Saururaceae (Lizard's-tail family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
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    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/53Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

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Abstract

The present invention relates to a kind of Chinese medicine composition for treating NUG, it is made up of following components according to weight fraction:20 30 parts of smilax, 5 15 parts of the root bark of shaggy-fruited dittany, 39 parts of tripterygium wilfordii, 39 parts of cape jasmine, 39 parts of kuh-seng, 39 parts of rattletop;10 20 parts of honeysuckle;5 15 parts of Herba Andrographitis;50 60 parts of purslane;5 15 parts of the Chinese bulbul;10 20 parts of cordate houttuynia, 5 15 parts of radix cynanchi atrati, 5 15 parts of earthworm.Chinese medicinal lotion of the present invention, easy to use, toxic side effect is small, is formed with theory of traditional Chinese medical science compatibility, effectively treats NUG.

Description

It is a kind of to treat Chinese medicine composition of NUG and preparation method thereof
Technical field
The present invention relates to technical field of traditional Chinese medicines, more particularly, to a kind of Chinese medicine composition for treating NUG.
Background technology
NUG (NGU) is common sexually transmitted disease (STD).Its incidence of disease rises increasingly in recent years, Occupy first of STD.Epididymitis, prostatitis, cervicitis, adnexitis, infertility, infertile, ectopic pregnancy etc. can often be caused, be may additionally facilitate The propagation of HIV, has a strong impact on patient physically and mentally healthy.Chlamydia trachomatis (CT) and Ureaplasma urealyticum (UU) are the main of this disease Pathogen.Due to the clinically abuse of antibacterials and irregular medication, cause antibody-resistant bacterium to be continuously increased, one is brought to treatment Fixed difficulty, so that clinically common patient symptom is persistently delayed or recurrent exerbation.Drawn by the long-term practice of inventor, Chinese medicine Controlling NUG has preferable effect, obtains good effect.
NUG belongs to the categories such as traditional Chinese medicine " stranguria ", " stranguria with turbid discharge ", and its cause of disease is more because sexual intercourse is unclean or infection Foul heresy, is entered, lower Jiao of retardance by excessive key or vaginal orifice, pents up bladder, change thermalization is fiery, cause functioning of bladder unfavorable, liver depression gas It is stagnant, qi and blood stagnation and cause.
The content of the invention
For defect present in prior art, it is an object of the invention to provide a kind of NUG for the treatment of Chinese medicine composition and preparation method thereof.
Technical scheme is as follows:
A kind of Chinese medicine composition for treating NUG, is made up of following components according to weight fraction:
20-30 parts of smilax, 5-15 parts of the root bark of shaggy-fruited dittany, 3-9 parts of tripterygium wilfordii, 3-9 parts of cape jasmine, 3-9 parts of kuh-seng, 3-9 parts of rattletop; 10-20 parts of honeysuckle;5-15 parts of Herba Andrographitis;50-60 parts of purslane;5-15 parts of the Chinese bulbul;10-20 parts of cordate houttuynia, radix cynanchi atrati 5-15 Part, 5-15 parts of earthworm.
A kind of Chinese medicine composition for treating NUG, is made up of following components according to weight fraction:
25 parts of smilax, 10 parts of the root bark of shaggy-fruited dittany, 6 parts of tripterygium wilfordii, 6 parts of cape jasmine, 6 parts of kuh-seng, 6 parts of rattletop;15 parts of honeysuckle;Wear 10 parts of heart lotus;55 parts of purslane;10 parts of the Chinese bulbul;15 parts of cordate houttuynia, 10 parts of radix cynanchi atrati, 10 parts of earthworm.
The Chinese medicine composition for the treatment of NUG as described above, specific preparation method is as follows:
1) each component in above-mentioned composition is weighed according to quantity;
2) above-mentioned each component is crushed to 50 mesh;
3) added after the composition after crushing is mixed in 2000 parts of water, immersion is decocted 30 minutes after 2 hours;
4) filter, discard filter residue, retain filtrate.
The Chinese medicine composition washing lotion for the treatment of NUG prepared by the present invention, is formulated with theory of traditional Chinese medical science, its In:Smilax removing toxic substances dehumidifying;The root bark of shaggy-fruited dittany is clearing heat and detoxicating, removing dampness to relieve itching;Tripterygium wilfordii dispelling wind and eliminating dampness, promoting blood circulation and removing obstruction in channels, desinsection detoxify, disappeared Swollen analgesic;Cape jasmine clearing heat and relieving fidgetness, eliminating dampness and heat, cooling blood and hemostasis;Kuh-seng heat-clearing and damp-drying drug, wind dispelling insecticide, diuresis;For monarch drug in a prescription;Rattletop Deliver promoting eruption, clearing heat and detoxicating, yang invigorating;It is honeysuckle dispelling wind and heat from the body, clearing heat and detoxicating;Herba Andrographitis is clearing heat and detoxicating, eliminating dampness;Purslane It is clearing heat and detoxicating, cooling blood and hemostasis, treating stranguria;The Chinese bulbul is clearing heat and detoxicating, cool blood;For ministerial drug;Cordate houttuynia is clearing heat and detoxicating, inducing diuresis for treating strangurtia; Radix cynanchi atrati clearing heat and cooling blood, inducing diuresis for treating strangurtia;Earthworm is clearing and activating the channels and collaterals, inducing diuresis for treating strangurtia;For adjutant.13 taste Chinese medicines are shared, play altogether dehumidifying, The effect of clearing heat and detoxicating, inducing diuresis for treating strangurtia, it can effectively treat NUG.
Chinese medicinal lotion of the present invention, easy to use, toxic side effect is small, is formed with theory of traditional Chinese medical science compatibility, effectively treatment NUG.
Embodiment
Embodiment 1
A kind of Chinese medicine composition for treating NUG, (every part is constituted by following components according to weight fraction 1g):
20 parts of smilax, 5 parts of the root bark of shaggy-fruited dittany, 3 parts of tripterygium wilfordii, 3 parts of cape jasmine, 3 parts of kuh-seng, 3 parts of rattletop;10 parts of honeysuckle;Wear 5 parts of heart lotus;50 parts of purslane;5 parts of the Chinese bulbul;10 parts of cordate houttuynia, 5 parts of radix cynanchi atrati, 5 parts of earthworm.
Specific preparation method is as follows:
1) each component in above-mentioned composition is weighed according to quantity;
2) above-mentioned each component is crushed to 50 mesh;
3) added after the composition after crushing is mixed in 2000 parts of water, immersion is decocted 30 minutes after 2 hours;
4) filter, discard filter residue, retain filtrate.
Embodiment 2
A kind of Chinese medicine composition for treating NUG, (every part is constituted by following components according to weight fraction 1g):
25 parts of smilax, 10 parts of the root bark of shaggy-fruited dittany, 6 parts of tripterygium wilfordii, 6 parts of cape jasmine, 6 parts of kuh-seng, 6 parts of rattletop;15 parts of honeysuckle;Wear 10 parts of heart lotus;55 parts of purslane;10 parts of the Chinese bulbul;15 parts of cordate houttuynia, 10 parts of radix cynanchi atrati, 10 parts of earthworm.
Preparation method is same as Example 1.
Embodiment 3
A kind of Chinese medicine composition for treating NUG, (every part is constituted by following components according to weight fraction 1g):
30 parts of smilax, 15 parts of the root bark of shaggy-fruited dittany, 9 parts of tripterygium wilfordii, 9 parts of cape jasmine, 9 parts of kuh-seng, 9 parts of rattletop;20 parts of honeysuckle;Wear 15 parts of heart lotus;60 parts of purslane;15 parts of the Chinese bulbul;20 parts of cordate houttuynia, 15 parts of radix cynanchi atrati, 15 parts of earthworm.
Preparation method is same as Example 1.
Inventor treated NUG female patient 84, clinical report is as follows altogether in 2009 to 2012:
1st, general information
In 84 patients, age 18-65 Sui, average age 29 years old, the course of disease was 10 days to 10 months, average course of disease 25 days.
2nd, diagnostic criteria
Diagnosis basis State Administration of Traditional Chinese Medicine issues《Chinese medical disease Standardization of diagnosis and curative effect》:
There is contaminated intercourse history;Urethral orifice has a little secretion, the slight cusalgia of urine, the training of secretion gonococcus from occurring morning repeatedly Yin-nourishing, Chlamydia and (or) Culture Mycoplasma are positive, serological test, Biological Detection Chlamydia and (or) mycoplasma sun Body.
3rd, treatment method
The Chinese medicinal lotion prepared using the embodiment of the present invention is cleaned, daily 1 dose, daily to clean 2 times, every time 10 points of cleaning Clock, the temperature of washing lotion, at 40-45 degrees Celsius, 10 days is 1 course for the treatment of, continuous using 3 courses for the treatment of, the property forbidden is given birth to during treatment during cleaning It is living.
4th, treatment results:
4.1 reference《Traditional Chinese medicine Clinical Researches of New Drugs guideline》Formulate:
Cure:Clinical symptom disappearance, the weak feminine gender of etiological examination.
Effectively:Clinical symptom disappearance, etiological examination weakly positive.
It is invalid:Clinical symptom relief, etiological examination is positive.
4.2 washing lotions prepared using the embodiment of the present invention 2 are treated after 3 courses for the treatment of, as a result as follows:Clinical cure 72, has Effect 11, invalid 1, total effective rate is 98.8%.
From above experimental example, the therapeutic effect of the Chinese medicinal lotion for treating NUG of the invention is notable.

Claims (2)

1. a kind of Chinese medicine composition for treating NUG, it is characterised in that by following components according to weight fraction group Into:
25 parts of smilax, 10 parts of the root bark of shaggy-fruited dittany, 6 parts of tripterygium wilfordii, 6 parts of cape jasmine, 6 parts of kuh-seng, 6 parts of rattletop;15 parts of honeysuckle;Herba Andrographitis 10 parts;55 parts of purslane;10 parts of the Chinese bulbul;15 parts of cordate houttuynia, 10 parts of radix cynanchi atrati, 10 parts of earthworm.
2. the Chinese medicine composition for the treatment of NUG according to claim 1, it is characterised in that specific to prepare Method is as follows:
1) each component in above-mentioned composition is weighed according to quantity;
2) above-mentioned each component is crushed to 50 mesh;
3) added after the composition after crushing is mixed in 2000 parts of water, immersion is decocted 30 minutes after 2 hours;
4) filter, discard filter residue, retain filtrate.
CN201410617206.9A 2014-11-05 2014-11-05 It is a kind of to treat Chinese medicine composition of NUG and preparation method thereof Active CN104306819B (en)

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Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2049416B (en) * 1979-05-24 1983-06-15 Laroche Navarron Sa Pharmaceutical composition
CN1060017C (en) * 1997-10-27 2001-01-03 崔凤玉 Rinse disinfectant liquid for sexual disease
CN100404054C (en) * 2005-02-03 2008-07-23 徐云裳 Decoction Chinese medicine sterilizing antiphlogistic, preparation and use thereof
CN103623302A (en) * 2013-12-02 2014-03-12 薛红丽 Traditional Chinese medicine composition for treating non-gonococcal urethritis

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