CN107080762B

CN107080762B - Application of sweet potato as medicine for treating hemorrhoids

Info

Publication number: CN107080762B
Application number: CN201710386383.4A
Authority: CN
Inventors: 乌恩奇; 乌日图
Original assignee: Individual
Current assignee: Individual
Priority date: 2017-05-26
Filing date: 2017-05-26
Publication date: 2020-06-30
Anticipated expiration: 2037-05-26
Also published as: CN107080762A

Abstract

Experiments show that the pachyrhizus has the effect of treating the hemorrhoids, can be directly used, and can also be used as a raw material medicine to be matched with other medicines so as to achieve the effect of treating the hemorrhoids.

Description

Application of sweet potato as medicine for treating hemorrhoids

Technical Field

The invention relates to application of pachyrhizus, in particular to application of the pachyrhizus as a medicine for treating hemorrhoids.

Background

The radix Pachyrhizi Erosi is also called radix Pachyrhizi Erosi, folium Ilicis Rotundae, cornu Naemorhedi, and radix Pachyrhizi Erosi, and is a perennial herb of Asclepiadaceae and goose down. The whole herb and fruit can be used as medicine, has the effects of tonifying lung qi, clearing heat, reducing pathogenic fire, promoting fluid production to quench thirst, diminishing inflammation, relieving pain, tonifying qi and promoting lactation, can be taken by people with weak body and milk, and can be used for treating neurasthenia and wart for external use.

In recent years, studies on the sweet potatoes mainly focus on chemical components, tissue culture and artificial domestication, content measurement and quality standards, and few pharmacological studies are carried out. The current research results show that main bioactive components in the pachyrhizus comprise triterpene compounds and flavonoids, oleanolic acid contained in the pachyrhizus is one of the triterpene compounds, and mainly has the effects of protecting liver, reducing enzyme, promoting hepatocyte regeneration, resisting inflammation, strengthening heart, promoting urination, resisting tumors and the like, the flavonoids have the effects of resisting inflammation and easing pain, and can be clinically used for treating abscess ulcer and inflammatory diseases caused by pathogenic microorganisms, and in addition, the antibacterial and antiviral effects of the flavonoids are widely researched, such as quercetin, kaempferol, luteolin and the like have the effects of resisting pathogenic microorganisms and viruses, and the flavonoids also have a certain inhibitory effect on various pathogenic fungi, such as candida albicans, trichophyton and the like. It is reported that succinic acid is one of chemical components in the sweet potato, can inhibit active and passive skin allergic reaction and can reduce the formation of IgE antibodies in animal serum, and has an inhibiting effect on staphylococcus aureus, catacoccus catarrhalis, typhoid, pyocyanea, proteus and dysentery bacillus at a concentration of 2 mg/L. Although the medicinal effects of the components are reported, the pharmacological activity of the pachyrhizus is only reported to have the effects of resisting oxidation and aging, and the research is still to be carried out deeply. Up to now, no other applications than the above-mentioned effects have been found.

Hemorrhoids are a chronic disease of one or more soft and lumpy veins formed by the varicose venous plexus of the anorectal base and the anal mucosa, and generally, when defecation is continuously applied, the pressure in the veins is repeatedly increased, the veins are enlarged, and the veins are formed into veins due to lumps over time to cause hemorrhoids. The incidence of hemorrhoids is high and reaches more than 60 percent, which is said to be nine hemorrhoids for ten people. Much better is found in adults, women are more than men in gestation period, because hemorrhoids are frequently generated due to compression of pelvic veins and obstruction of blood circulation, and many obese people are also easy to suffer from hemorrhoids, and children and teenagers under 18 years old are rare.

The hemorrhoid includes internal hemorrhoid, external hemorrhoid, and mixed hemorrhoid. The primary and only symptom of early internal hemorrhoids is painless hemafecia. It features intermittent hematochezia, bright color, adhesion to the surface of stool, or staining of toilet paper, and drop or spray bleeding. Anemia may result if the blood is taken for a long time; the internal hemorrhoids further develop, and the hemorrhoids may be prolapsed during defecation, so the patient with mild condition can return to the anus by himself or herself, and the patient with severe condition needs to push the hand upwards to return to the anus. When the internal hemorrhoid is not withdrawn in time, incarceration edema, thrombosis, ulcer or infection will occur, and severe pain will occur. External hemorrhoids are generally asymptomatic and sometimes can prolapse or protrude from the anus. However, this condition only occurs when defecation occurs, after which it retracts to its original position, with occasional tenesmus and discomfort, but can be painful when thrombi, edema, etc. occur. The mixed hemorrhoid has the common characteristics of internal hemorrhoid and external hemorrhoid. Thrombosis can occur in both internal and external hemorrhoids. When thrombus occurs, blood in the hemorrhoid coagulates into blocks, causing pain, and in addition, anus foreign body sensation, underwear pollution and local pruritus are common symptoms.

The treatment methods of the hemorrhoids are various and comprise drug therapy and non-drug therapy, and the drugs can be divided into oral administration and external application, wherein the external application drugs are common and easily accepted treatment modes. The external medicine adopts traditional Chinese medicines for clearing heat and removing toxicity and relieving constipation, is decocted for external washing, such as a bitter ginseng decoction, and also adopts a traditional Chinese medicine or a Chinese and western medicine mixture which is easy to be absorbed by skin to be used as an ointment, a medicinal cloth and a Changqiang acupoint which is stuck on the umbilical region or the sacral tail part for treatment, but the curative effect is not ideal, for example, the effective time is long, the recurrence is easy, and the like.

Disclosure of Invention

Therefore, the technical problem to be solved by the invention is to overcome the defect that the curative effect of the external medicine for treating the hemorrhoids in the prior art is not ideal, and the applicant finds that the external medicine can treat the hemorrhoids and has a remarkable effect in the research of the pachyrhizus, so that the application of the pachyrhizus as the medicine for treating the hemorrhoids is provided.

Therefore, the technical proposal adopted by the application is that,

application of radix Pachyrhizi Erosi in preparing medicine for treating hemorrhoid is provided.

Preferably, in the application of the pachyrhizus to the preparation of the medicine for treating hemorrhoids, the dried pachyrhizus is decocted, and the water decoction is used for fumigating the affected part or washing the affected part.

The technical scheme of the invention has the following advantages:

the invention provides application of the sweet potato in preparing the medicine for treating the hemorrhoids, which expands the application range of the sweet potato on one hand and provides an effective medicine or raw material medicine for treating the hemorrhoids, and the invention has the advantages of simple method, obvious effect and expansion of medicine selection for treating the hemorrhoids on the other hand. The pachyrhizus is a natural product, has no toxicity, little side effect, no contraindication, no adverse reaction, safety and reliability.

Detailed Description

Example 1

Drying whole plant of radix Pachyrhizi Erosi, pulverizing, adding 100g water into 1000g water, boiling for 15min to obtain medicinal liquid, fumigating the affected part with hot gas, cooling, and rinsing the affected part with the medicinal liquid 2 times daily.

In order to explore the effectiveness and safety of the pachyrhizus for treating hemorrhoids, clinical trials are carried out, and the experimental conditions are as follows:

1. the research method comprises the following steps: 60 patients with hemorrhoids were treated with the drug solution and method prepared in example 1 using an open, self-control study for a week.

2. The selected cases were: 60 cases, wherein the mixed hemorrhoid is 40 cases, the external hemorrhoid is 20 cases, the male is 30 cases, the female is 30 cases, the age is 40-70 years, the average age is 45 years, and the affected time is 2-30 years.

3. The therapeutic effect judgment standard is as follows:

3.1 Mixed hemorrhoid

And (3) healing: after defecation, no bleeding and no prolapse exist, hemorrhoid mucosa is recovered to be normal by anoscopy, and hemorrhoid atrophy disappears.

The effect is shown: after defecation, no bleeding and no prolapse occur, the red and swollen hemorrhoids obviously subside, the anal speculum examination shows that the mucosa of the internal hemorrhoids is slightly congested and the hemorrhoids become small.

The method has the following advantages: there was still a small amount of bleeding after defecation with mild prolapse, and mild congestion of hemorrhoid mucosa was examined by anoscope.

And (4) invalidation: the symptoms or body fragments were not improved or even exacerbated as compared to those before treatment.

3.2 external hemorrhoid

And (3) healing: the symptoms or signs disappear.

The effect is shown: the symptoms disappeared and signs improved.

The method has the following advantages: symptoms and signs improved.

And (4) invalidation: no improvement in symptoms and signs

4. The treatment effect is as follows: no adverse reaction is seen during the treatment period, and the specific effects are shown in Table 1

TABLE 1 Effect data of sweet potato on hemorrhoid treatment

	Recovery method	Show effect	Is effective	Invalidation
					Mixed hemorrhoid	6	13	17	4
External hemorrhoid	3	8	7	2

Typical cases

1. Plum, male, 55 years old, suffering from swelling and pain of hemorrhoids for 5 years, with symptoms: the anal lithotomy position has multiple edema, erosion, purple dark color and touch pain, and the diabetes doctor does not recommend the operation, so the applicant recommends that the method in the embodiment 1 is adopted for treatment, the pain disappears after 5 days, the swelling subsides after 8 days, and the hemorrhoids are obviously reduced after 15 days.

2. Yangzhi, male, age 40, driver, symptoms: edema, erosion, purple darkness, pain on touch, and multiple visits with repeated attacks, with the applicant's suggestion that the treatment with the method of example 1, pain disappeared after 7 days, swelling subsided after 10 days, haemorrhoids disappeared after 30 days and did not attack until now.

3. In another woman, 35 who suffered from hemorrhoids during pregnancy for 3 years to date, had painful defecation and occasional bloody stool, the applicant suggested that the treatment of the hemorrhoid in example 1 was carried out after 30 days, and had no onset, relaxed defecation and bloody stool.

It should be understood that the above examples are only for clarity of illustration and are not intended to limit the embodiments. Other variations and modifications will be apparent to persons skilled in the art in light of the above description. And are neither required nor exhaustive of all embodiments. And obvious variations or modifications therefrom are within the scope of the invention.

Claims

1. Application of radix Pachyrhizi Erosi in preparing medicine for treating hemorrhoid is provided.

2. The use of a sweet potato according to claim 1 for the manufacture of a medicament for the treatment of hemorrhoids, wherein the sun-dried sweet potato is decocted and the decoction is taken to fumigate or rinse the affected area.