CN105441549A - 烷基胺改进甲醛固定的生物样品组分的检测 - Google Patents

烷基胺改进甲醛固定的生物样品组分的检测 Download PDF

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Publication number
CN105441549A
CN105441549A CN201510970816.1A CN201510970816A CN105441549A CN 105441549 A CN105441549 A CN 105441549A CN 201510970816 A CN201510970816 A CN 201510970816A CN 105441549 A CN105441549 A CN 105441549A
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CN
China
Prior art keywords
sample
components
formaldehyde
nucleic acid
alkylamine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201510970816.1A
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English (en)
Chinese (zh)
Inventor
S·G·威尔
V·博德普迪
E·H·菲斯
R·沙希尼安
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Priority claimed from CN200880010876A external-priority patent/CN101657711A/zh
Publication of CN105441549A publication Critical patent/CN105441549A/zh
Pending legal-status Critical Current

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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CN201510970816.1A 2007-03-30 2008-03-26 烷基胺改进甲醛固定的生物样品组分的检测 Pending CN105441549A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US92093907P 2007-03-30 2007-03-30
US60/920939 2007-03-30
US95472107P 2007-08-08 2007-08-08
US60/954721 2007-08-08
CN200880010876A CN101657711A (zh) 2007-03-30 2008-03-26 烷基胺改进甲醛固定的生物样品组分的检测

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN200880010876A Division CN101657711A (zh) 2007-03-30 2008-03-26 烷基胺改进甲醛固定的生物样品组分的检测

Publications (1)

Publication Number Publication Date
CN105441549A true CN105441549A (zh) 2016-03-30

Family

ID=39570687

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201510970816.1A Pending CN105441549A (zh) 2007-03-30 2008-03-26 烷基胺改进甲醛固定的生物样品组分的检测

Country Status (8)

Country Link
US (2) US8652775B2 (https=)
EP (1) EP2132549B1 (https=)
JP (2) JP2010522544A (https=)
CN (1) CN105441549A (https=)
CA (1) CA2681584C (https=)
ES (1) ES2436023T3 (https=)
HK (1) HK1223128A1 (https=)
WO (1) WO2008119488A1 (https=)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN115135984A (zh) * 2019-12-23 2022-09-30 10X基因组学有限公司 可逆固定试剂及其使用方法
US12297488B2 (en) 2010-04-05 2025-05-13 Prognosys Biosciences, Inc. Spatially encoded biological assays

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* Cited by examiner, † Cited by third party
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US8420801B2 (en) * 2010-01-08 2013-04-16 Roche Molecular Systems, Inc. Recovery of nucleic acids from magnetic glass particles
US9416356B2 (en) * 2013-03-15 2016-08-16 Abbott Molecular Inc. Compositions and methods for nucleic acid extraction
US9771572B2 (en) 2014-02-28 2017-09-26 Gen-Probe Incorporated Method of isolating nucleic acid from specimens in liquid-based cytology preservatives containing formaldehyde
US9771571B2 (en) 2014-02-28 2017-09-26 Gen-Probe Incorporated Method of isolating nucleic acid from specimens in liquid-based cytology preservatives containing formaldehyde
CN111484992B (zh) * 2014-02-28 2024-04-02 简·探针公司 从含有甲醛的液基细胞学防腐剂中的样本分离核酸的方法
US20170283860A1 (en) * 2014-09-16 2017-10-05 The Board Of Trustees Of The Leland Stanford Junio University Methods and compositions for the removal of aldehyde adducts and crosslinks from biomolecules
WO2017200350A1 (ko) 2016-05-20 2017-11-23 엘지전자 주식회사 로봇 청소기
EP3459419B1 (en) 2016-05-20 2022-10-26 LG Electronics Inc. Robot cleaner
GB201704823D0 (en) * 2017-03-27 2017-05-10 Univ Leicester Methods and kits for determining binding sites
US10995104B2 (en) 2017-05-30 2021-05-04 Roche Molecular System, Inc. Catalysts for reversing formaldehyde adducts and crosslinks
EP4705736A1 (en) * 2023-05-04 2026-03-11 Promega Corporation Compositions and methods for decrosslinking biological samples
US20240369459A1 (en) * 2023-05-04 2024-11-07 Promega Corporation Methods and compositions for decrosslinking biological samples

Citations (3)

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US6649368B1 (en) * 1997-10-24 2003-11-18 Cell Marque Corporation Composition and method for treating tissue samples
US20040038264A1 (en) * 2002-05-14 2004-02-26 Souza Glauco R. Fractal dimension analysis of nanoparticle aggregates using angle dependent light scattering for the detection and characterization of nucleic acids and proteins
CN1653175A (zh) * 2002-02-26 2005-08-10 第三次浪潮技术公司 Rna检测酶

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ATE88761T1 (de) * 1986-01-10 1993-05-15 Amoco Corp Kompetitiver homogener test.
US5977343A (en) * 1992-05-14 1999-11-02 Ribozyme Pharmaceuticals, Inc. Synthesis, deprotection, analysis and purification of RNA and ribozymes
EP0607422B1 (en) * 1992-08-12 2002-03-13 Biogenex Laboratories Enhancement of immunochemical staining in aldehyde-fixed tissues
US7653212B2 (en) 2006-05-19 2010-01-26 Universal Electronics Inc. System and method for using image data in connection with configuring a universal controlling device
US20040029184A1 (en) * 2002-08-09 2004-02-12 Pickcell Laboratories B.V. Method for antigen retrieval and submersion fluid compositions for use therein
US20050032146A1 (en) 2003-08-07 2005-02-10 Herr John C. Tssk4: a human testis specific serine/threonine kinase
US7318925B2 (en) * 2003-08-08 2008-01-15 Amgen Fremont, Inc. Methods of use for antibodies against parathyroid hormone
JP2006124154A (ja) * 2004-09-29 2006-05-18 Toshiba Tec Corp 用紙後処理装置
WO2006066039A2 (en) * 2004-12-17 2006-06-22 Kram Brian H High temperature tissue conditioning with low volatility solutions and applications
DE102005060738A1 (de) 2005-12-16 2007-06-21 Qiagen Gmbh Verfahren zur Extraktion von Biomolekülen aus fixierten Geweben
EP1911844A1 (en) * 2006-10-10 2008-04-16 Qiagen GmbH Methods and kit for isolating nucleic acids

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6649368B1 (en) * 1997-10-24 2003-11-18 Cell Marque Corporation Composition and method for treating tissue samples
CN1653175A (zh) * 2002-02-26 2005-08-10 第三次浪潮技术公司 Rna检测酶
US20040038264A1 (en) * 2002-05-14 2004-02-26 Souza Glauco R. Fractal dimension analysis of nanoparticle aggregates using angle dependent light scattering for the detection and characterization of nucleic acids and proteins

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US12297488B2 (en) 2010-04-05 2025-05-13 Prognosys Biosciences, Inc. Spatially encoded biological assays
US12297487B2 (en) 2010-04-05 2025-05-13 Prognosys Biosciences, Inc. Spatially encoded biological assays
US12391979B2 (en) 2010-04-05 2025-08-19 Prognosys Biosciences, Inc. Spatially encoded biological assays
US12391980B2 (en) 2010-04-05 2025-08-19 Prognosys Biosciences, Inc. Spatially encoded biological assays
CN115135984A (zh) * 2019-12-23 2022-09-30 10X基因组学有限公司 可逆固定试剂及其使用方法
US12566113B2 (en) 2019-12-23 2026-03-03 10X Genomics, Inc. Reversible fixing reagents and methods of use thereof

Also Published As

Publication number Publication date
JP2010522544A (ja) 2010-07-08
US20140120547A1 (en) 2014-05-01
EP2132549A1 (en) 2009-12-16
US9400235B2 (en) 2016-07-26
WO2008119488A1 (en) 2008-10-09
US8652775B2 (en) 2014-02-18
ES2436023T3 (es) 2013-12-26
CA2681584A1 (en) 2008-10-09
EP2132549B1 (en) 2013-09-11
HK1223128A1 (zh) 2017-07-21
JP5792769B2 (ja) 2015-10-14
JP2013200317A (ja) 2013-10-03
CA2681584C (en) 2013-10-22
US20090081661A1 (en) 2009-03-26

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