CA2681584C - Alkyl amines improve detection of components of formaldehyde-fixed biological samples - Google Patents

Alkyl amines improve detection of components of formaldehyde-fixed biological samples Download PDF

Info

Publication number
CA2681584C
CA2681584C CA2681584A CA2681584A CA2681584C CA 2681584 C CA2681584 C CA 2681584C CA 2681584 A CA2681584 A CA 2681584A CA 2681584 A CA2681584 A CA 2681584A CA 2681584 C CA2681584 C CA 2681584C
Authority
CA
Canada
Prior art keywords
alkyl amine
cross
sample
components
nucleic acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2681584A
Other languages
English (en)
French (fr)
Other versions
CA2681584A1 (en
Inventor
Stephen Gordon Will
Veeraiah Bodepudi
Ellen H. Fiss
Rachel Shahinian
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of CA2681584A1 publication Critical patent/CA2681584A1/en
Application granted granted Critical
Publication of CA2681584C publication Critical patent/CA2681584C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6806—Preparing nucleic acids for analysis, e.g. for polymerase chain reaction [PCR] assay

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CA2681584A 2007-03-30 2008-03-26 Alkyl amines improve detection of components of formaldehyde-fixed biological samples Active CA2681584C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US92093907P 2007-03-30 2007-03-30
US60/920,939 2007-03-30
US95472107P 2007-08-08 2007-08-08
US60/954,721 2007-08-08
PCT/EP2008/002356 WO2008119488A1 (en) 2007-03-30 2008-03-26 Alkyl amines improve detection of components of formaldehyde-fixed biological samples

Publications (2)

Publication Number Publication Date
CA2681584A1 CA2681584A1 (en) 2008-10-09
CA2681584C true CA2681584C (en) 2013-10-22

Family

ID=39570687

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2681584A Active CA2681584C (en) 2007-03-30 2008-03-26 Alkyl amines improve detection of components of formaldehyde-fixed biological samples

Country Status (8)

Country Link
US (2) US8652775B2 (https=)
EP (1) EP2132549B1 (https=)
JP (2) JP2010522544A (https=)
CN (1) CN105441549A (https=)
CA (1) CA2681584C (https=)
ES (1) ES2436023T3 (https=)
HK (1) HK1223128A1 (https=)
WO (1) WO2008119488A1 (https=)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8420801B2 (en) * 2010-01-08 2013-04-16 Roche Molecular Systems, Inc. Recovery of nucleic acids from magnetic glass particles
US10787701B2 (en) 2010-04-05 2020-09-29 Prognosys Biosciences, Inc. Spatially encoded biological assays
US9416356B2 (en) * 2013-03-15 2016-08-16 Abbott Molecular Inc. Compositions and methods for nucleic acid extraction
US9771572B2 (en) 2014-02-28 2017-09-26 Gen-Probe Incorporated Method of isolating nucleic acid from specimens in liquid-based cytology preservatives containing formaldehyde
US9771571B2 (en) 2014-02-28 2017-09-26 Gen-Probe Incorporated Method of isolating nucleic acid from specimens in liquid-based cytology preservatives containing formaldehyde
CN111484992B (zh) * 2014-02-28 2024-04-02 简·探针公司 从含有甲醛的液基细胞学防腐剂中的样本分离核酸的方法
US20170283860A1 (en) * 2014-09-16 2017-10-05 The Board Of Trustees Of The Leland Stanford Junio University Methods and compositions for the removal of aldehyde adducts and crosslinks from biomolecules
WO2017200350A1 (ko) 2016-05-20 2017-11-23 엘지전자 주식회사 로봇 청소기
EP3459419B1 (en) 2016-05-20 2022-10-26 LG Electronics Inc. Robot cleaner
GB201704823D0 (en) * 2017-03-27 2017-05-10 Univ Leicester Methods and kits for determining binding sites
US10995104B2 (en) 2017-05-30 2021-05-04 Roche Molecular System, Inc. Catalysts for reversing formaldehyde adducts and crosslinks
CN115135984B (zh) * 2019-12-23 2025-12-23 10X基因组学有限公司 可逆固定试剂及其使用方法
EP4705736A1 (en) * 2023-05-04 2026-03-11 Promega Corporation Compositions and methods for decrosslinking biological samples
US20240369459A1 (en) * 2023-05-04 2024-11-07 Promega Corporation Methods and compositions for decrosslinking biological samples

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE88761T1 (de) * 1986-01-10 1993-05-15 Amoco Corp Kompetitiver homogener test.
US7150982B2 (en) * 1991-09-09 2006-12-19 Third Wave Technologies, Inc. RNA detection assays
US5977343A (en) * 1992-05-14 1999-11-02 Ribozyme Pharmaceuticals, Inc. Synthesis, deprotection, analysis and purification of RNA and ribozymes
EP0607422B1 (en) * 1992-08-12 2002-03-13 Biogenex Laboratories Enhancement of immunochemical staining in aldehyde-fixed tissues
US6649368B1 (en) * 1997-10-24 2003-11-18 Cell Marque Corporation Composition and method for treating tissue samples
US20040038264A1 (en) * 2002-05-14 2004-02-26 Souza Glauco R. Fractal dimension analysis of nanoparticle aggregates using angle dependent light scattering for the detection and characterization of nucleic acids and proteins
US7653212B2 (en) 2006-05-19 2010-01-26 Universal Electronics Inc. System and method for using image data in connection with configuring a universal controlling device
US20040029184A1 (en) * 2002-08-09 2004-02-12 Pickcell Laboratories B.V. Method for antigen retrieval and submersion fluid compositions for use therein
US20050032146A1 (en) 2003-08-07 2005-02-10 Herr John C. Tssk4: a human testis specific serine/threonine kinase
US7318925B2 (en) * 2003-08-08 2008-01-15 Amgen Fremont, Inc. Methods of use for antibodies against parathyroid hormone
JP2006124154A (ja) * 2004-09-29 2006-05-18 Toshiba Tec Corp 用紙後処理装置
WO2006066039A2 (en) * 2004-12-17 2006-06-22 Kram Brian H High temperature tissue conditioning with low volatility solutions and applications
DE102005060738A1 (de) 2005-12-16 2007-06-21 Qiagen Gmbh Verfahren zur Extraktion von Biomolekülen aus fixierten Geweben
EP1911844A1 (en) * 2006-10-10 2008-04-16 Qiagen GmbH Methods and kit for isolating nucleic acids

Also Published As

Publication number Publication date
JP2010522544A (ja) 2010-07-08
US20140120547A1 (en) 2014-05-01
EP2132549A1 (en) 2009-12-16
CN105441549A (zh) 2016-03-30
US9400235B2 (en) 2016-07-26
WO2008119488A1 (en) 2008-10-09
US8652775B2 (en) 2014-02-18
ES2436023T3 (es) 2013-12-26
CA2681584A1 (en) 2008-10-09
EP2132549B1 (en) 2013-09-11
HK1223128A1 (zh) 2017-07-21
JP5792769B2 (ja) 2015-10-14
JP2013200317A (ja) 2013-10-03
US20090081661A1 (en) 2009-03-26

Similar Documents

Publication Publication Date Title
CA2681584C (en) Alkyl amines improve detection of components of formaldehyde-fixed biological samples
JPH02303489A (ja) ランダム配列のオリゴヌクレオチドをプライマーとして用いた核酸配列の増幅
US20140186821A1 (en) Noninterfering Multipurpose Compositions for Collecting, Transporting and Storing Biological Samples
CN111406118B (zh) 呼吸道合胞病毒种属的切口产生和延伸扩增反应(near)
US20170349936A1 (en) Noninterfering Multipurpose Compositions for Collecting, Transporting and Storing Biological Samples
JP6637100B2 (ja) ホルムアルデヒドを含有する液体系細胞診用保存剤中検体から核酸を単離する方法
KR20230007464A (ko) 호흡기 병원체 검출을 위한 검체수송 키트 및 이를 이용한 호흡기 병원체 검출방법
US10995104B2 (en) Catalysts for reversing formaldehyde adducts and crosslinks
CN101657711A (zh) 烷基胺改进甲醛固定的生物样品组分的检测
WO2003070986A1 (en) Removal of nucleic acid contaminants
HK1139735A (en) Alkyl amines improve detection of components of formaldehyde-fixed biological samples
US20080199857A1 (en) Method of increasing specificity of nucleic acid hybridization using zwitterionic compound
TW202204635A (zh) 銀色葡萄球菌之檢測用之引子組及探針
JP4418450B2 (ja) 生物学的ｄｎａの検出
JP2000093176A (ja) 核酸合成法
JP2007515181A (ja) 核酸検出のための固相支持体
JP4187057B2 (ja) 核酸合成法
HK40025966A (en) Nicking and extension amplification reaction (near) of respiratory syncytial virus species
AU2003205424B2 (en) Removal of nucleic acid contaminants
Hanon et al. The Use of Hypervariable Genomic Dna Loci for Gender Determination

Legal Events

Date Code Title Description
EEER Examination request
MPN Maintenance fee for patent paid

Free format text: FEE DESCRIPTION TEXT: MF (PATENT, 17TH ANNIV.) - STANDARD

Year of fee payment: 17

U00 Fee paid

Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U00-U101 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE REQUEST RECEIVED

Effective date: 20250227

U11 Full renewal or maintenance fee paid

Free format text: ST27 STATUS EVENT CODE: A-4-4-U10-U11-U102 (AS PROVIDED BY THE NATIONAL OFFICE); EVENT TEXT: MAINTENANCE FEE PAYMENT DETERMINED COMPLIANT

Effective date: 20250227