CN105435038A - External ointment for treating scrotal damp itch and preparation method for external ointment - Google Patents

External ointment for treating scrotal damp itch and preparation method for external ointment Download PDF

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CN105435038A
CN105435038A CN201610000085.2A CN201610000085A CN105435038A CN 105435038 A CN105435038 A CN 105435038A CN 201610000085 A CN201610000085 A CN 201610000085A CN 105435038 A CN105435038 A CN 105435038A
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radix
externally
appropriate
applied ointment
damp
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罗倩茹
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Chengdu Beijiate Biotechnology Co Ltd
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Chengdu Beijiate Biotechnology Co Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/13—Coniferophyta (gymnosperms)
    • A61K36/15—Pinaceae (Pine family), e.g. pine or cedar
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/234—Cnidium (snowparsley)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/238—Saposhnikovia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284—Atractylodes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/35—Caprifoliaceae (Honeysuckle family)
    • A61K36/355—Lonicera (honeysuckle)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489—Sophora, e.g. necklacepod or mamani
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/634—Forsythia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/756—Phellodendron, e.g. corktree
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/904—Stemonaceae (Stemona family), e.g. croomia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels

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  • Health & Medical Sciences (AREA)
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Abstract

The invention belongs to the technical field of traditional Chinese medicines, and aims to provide an external ointment for treating scrotal damp itch based on the mechanism of traditional Chinese medical science to understand external ointments. The external ointment comprises the following components by mass: 5-15 g of radix stemonae, 3-10 g of radix sophorae flavescentis, 7.5-15 g of rhizoma atractylodis, 3-15 g of cnidium fruit, 7.5-15 g of cortex phellodendri (fried), 16-20 g of fructus forsythiae, 5-15 g of cortex pseudolaricis, 12-22 g of flos lonicerae, 5-12 g of radix saposhnikoviae, 0.15-0.35 g of borneol, a proper amount of chlorhexidine acetate and a proper amount of peppermint camphor.

Description

A kind ofly treat externally-applied ointment of scrotum pruritus due to damp pathogen and preparation method thereof
Technical field
The present invention relates to technical field of Chinese medicine, be specifically related to a kind of externally-applied ointment for the treatment of scrotum pruritus due to damp pathogen, particularly for the field of the externally-applied ointment and preparation method thereof of scrotum pruritus due to damp pathogen patient.
Background technology
Scrotum pruritus due to damp pathogen, belongs to eczema symptom, and eczema scrotum is that a kind of common skin of scrotum is sick, and be not sexually transmitted disease, summer, sickness rate was the highest.Once can very itch incomparably in morbidity patient affected part, occur various little pimple, erosion etc., and the course of disease is longer.If do not do scientific and normal complete treatment, easy recurrent exerbation, delay is difficult.
Mainly clinically to diagnose according to patient's medical history, pathogenic process, disease feature, also need if desired to do antibacterial or Fungus examination is made a definite diagnosis.
The medical history diagnosis of a, eczema scrotum: patient mostly is anaphylaxis, exudative body constitution, has scholar to think, allergic constitution and heritability IgA lack certain relation.
The disease feature diagnosis of b, eczema scrotum: skin lesion is various, come in every shape, and have and merge and ooze out tendency.
Erosive type, i.e. acute and subacute stage, morbidity is very fast, scrotal swelling, flushing, pruritus, rotten to the corn sepage, forms a scab, comes off and have a small amount of pityrosporum shape desquamation, outbreak in intermittent or paroxysmal, when night or emotion changes more so.As: secondary infection, vesicle then becomes pustule.
So, just how finding a kind of medicine effectively can treating above-mentioned scrotum pruritus due to damp pathogen, is our current problem in urgent need to solve.
Summary of the invention
Along with the development of China's Chinese medicine, on treatment scrotum pruritus due to damp pathogen, people appreciate the advantage of the above-mentioned scrotum pruritus due to damp pathogen of Chinese traditional treatment gradually, and the advantage such as toxic and side effects is little over the course for the treatment of, expense is low, for the present situation of the above-mentioned scrotum pruritus due to damp pathogen of existing western medical treatment, the object of the invention is to be to provide a kind of externally-applied ointment for the treatment of scrotum pruritus due to damp pathogen, to solve scrotum pruritus due to damp pathogen patient restorative problem early.This externally-applied ointment be with common Chinese medicine for raw material, there is instant effect, the feature such as evident in efficacy, and effectively can treat above-mentioned scrotum pruritus due to damp pathogen.
For reaching the object of foregoing invention, the technical solution adopted in the present invention is: provide a kind of and treat externally-applied ointment of scrotum pruritus due to damp pathogen and preparation method thereof, it is characterized in that, each component of described externally-applied ointment and mass parts thereof are than as follows:
The Radix Stemonae 5 ~ 15g, Radix Sophorae Flavescentis 3 ~ 10g, Rhizoma Atractylodis 7.5 ~ 15g, Fructus Cnidii 3 ~ 15g, Cortex Phellodendri (stir-fry) 7.5 ~ 15g, Fructus Forsythiae 16 ~ 20g, Cortex Pseudolaricis 5 ~ 15g, Flos Lonicerae 12 ~ 22g, Radix Saposhnikoviae 5 ~ 12g, Borneolum Syntheticum 0.15 ~ 0.35g, chlorhexidine acetate is appropriate, Mentholum is appropriate.
A kind ofly treat externally-applied ointment of scrotum pruritus due to damp pathogen and preparation method thereof, it is characterized in that, institute
State each component of externally-applied ointment and mass parts thereof than as follows:
The Radix Stemonae 7 ~ 13g, Radix Sophorae Flavescentis 4 ~ 9g, Rhizoma Atractylodis 8 ~ 13g, Fructus Cnidii 4 ~ 13g, Cortex Phellodendri (stir-fry) 8 ~ 13g, Fructus Forsythiae 16 ~ 17g, Cortex Pseudolaricis 6 ~ 13g, Flos Lonicerae 13 ~ 20g,
Radix Saposhnikoviae 6 ~ 11g, Borneolum Syntheticum 0.20 ~ 0.30g, chlorhexidine acetate is appropriate, Mentholum is appropriate.
A kind ofly treat externally-applied ointment of scrotum pruritus due to damp pathogen and preparation method thereof, it is characterized in that, each component of the externally-applied ointment of described " preferred plan " and mass parts thereof are than as follows:
Radix Stemonae 12g, Radix Sophorae Flavescentis 8g, Rhizoma Atractylodis 12g, Fructus Cnidii 12g, Cortex Phellodendri (stir-fry) 12g, Fructus Forsythiae 15g, Cortex Pseudolaricis 12g, Flos Lonicerae 18g, Radix Saposhnikoviae 10g, Borneolum Syntheticum 0.25g, chlorhexidine acetate is appropriate, Mentholum is appropriate.
A kind ofly treat externally-applied ointment of scrotum pruritus due to damp pathogen and preparation method thereof, it is characterized in that, described method comprises the steps to be prepared from:
A, above-mentioned raw materials Chinese medicine is picked decontamination and dust after, be ground into superfine end (adopting ultra tiny machine to grind) according to mass parts ratio stand-by;
B, traditionally prepare the method for traditional Chinese herb medicine, after being sieved by ground superfine myrrh thing, put into medicine device and mix, then add appropriate chlorhexidine acetate and Mentholum is mixed all, obtain ointment shape final drug, bottled sealing can be for subsequent use.
Externally-applied ointment of a kind of above-mentioned treatment scrotum pruritus due to damp pathogen and preparation method thereof, it is characterized in that, described using method is: put ointment shape final drug on the skin cleaning up site of disease, massage absorption simultaneously, have hotness for degree, after 5-10 days with skin, transference cure, disease obtains recovery from illness.
Each raw material Chinese medicine in prescription of the present invention is all documented in detail in Chinese Pharmacopoeia, Chinese dictionary and Chinese book on Chinese herbal medicine.The present invention selects wherein modal Chinese medicine to be raw material, gives full play to the pharmacological effect of each component:
The Radix Stemonae, nature and flavor: sweet in the mouth, hardship, slightly warm in nature, have effect of gentle lung qi, cough-relieving, parasite killing, can be used for treatment cough due to wind and cold, pertussis, pulmonary tuberculosis, old cough with asthma, ascarid, enterobiasis, skin scabies, eczema;
Radix Sophorae Flavescentis, nature and flavor: bitter, cold, have effect of heat clearing and damp drying, parasite killing, diuresis, are used for the treatment of hematodiarrhoea, have blood in stool, the disease such as jaundice urine retention, leucorrhea with red and white discharge, swelling of the vulva pudendal pruritus, eczema, eczema, skin pruritus, scabies leprosy, external treatment trichomonal vaginitis;
Rhizoma Atractylodis, nature and flavor: acrid in the mouth, hardship, warm in nature, there is effect of drying damp and strengthening spleen, wind-damp dispelling, improving eyesight, be used for the treatment of the spleen and stomach being stranded by dampness, asthenia drowsiness, born of the same parents' painful abdominal mass abdominal distention, inappetence, tell have loose bowels, the disease such as phlegm retention, damp-edema, exterior syndrome folder is wet, head heavy sensation of the body pain, arthromyodynia warm nature, podomere are ached weighs, flaccidity folds in a garment, nyctalopia;
Fructus Cnidii, nature and flavor: acrid, bitter, warm, slightly poisonous, there is removing toxic substances parasite killing, dampness, the effect of dispeling the wind, infertile for external treatment vulval eczema, married woman's pudendal pruritus, trichomonal vaginitis, eczema scabies, cold-damp leukorrhagia, arthralgia chiefly caused by damp pathogen lumbago, impotence due to deficiency of the kidney, cold womb;
Cortex Phellodendri (stir-fry), nature and flavor: bitter, cold, there is heat clearing and damp drying, eliminating fire and detoxication, effect except hectic fever due to YIN-deficiency clearind deficient heat, be used for the treatment of damp-heat dysentery, the disease such as jaundice, leukorrhagia, pyretic stranguria, beriberi, flaccidity are warded off, hectic fever due to YIN-deficiency consumptive fever, night sweat, seminal emission, sore swollen toxin, eczema pruritus;
Fructus Forsythiae, nature and flavor: bitter, cold nature, has effect of heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, anemopyretic cold, be used for the treatment of the diseases such as anemopyretic cold, epidemic febrile disease, pyretic stranguria urine retention, carbuncle, toxic swelling, scrofula, goiter, sore throat;
Cortex Pseudolaricis, nature and flavor: warm in nature, acrid in the mouth, poisonous, there is parasite killing, antipruritic effect, be used for the treatment of scabies pruritus;
Flos Lonicerae, nature and flavor: sweet, cold effect with heat-clearing and toxic substances removing, is used for the treatment of epidemic febrile disease heating, toxic-heat and blood stasis, carbuncle furuncle, sore throat and multi-infection disease;
Radix Saposhnikoviae, nature and flavor: acrid in the mouth, sweet, slightly warm in nature, have effect that expelling pathogenic wind from the body surface, removing dampness to relieve pain, relieving convulsion are jerked surely, are used for the treatment of diseases caused by exogenous pathogenic factor exterior syndrome, rubella pruritus, rheumatic arthralgia, tetanus;
Borneolum Syntheticum, nature and flavor: pungent, bitter, are slightly cold.There is logical all keys, loose stagnated fire, removing nebula improving eyesight, reducing swelling and alleviating pain, can be used for treatment apoplexy locked mouth, calentura god mistake, infantile convulsion expectorant fan, deafness with qi stagnation, sore throat, aphtha, otitis media, carbuncle, hemorrhoid, order also nebula film, enterobiasis.
Medicine of the present invention is differential diagnosis of diseases based on Chinese traditional treatment scrotum pruritus due to damp pathogen and the dialectical principle combined, think from pharmacological action and mechanism of action: with regard to scrotum pruritus due to damp pathogen one disease, each raw material herbal medicine efficacy in medicine provided by the present invention is played altogether, has good therapeutic effect to above-mentioned disease.
Detailed description of the invention
The present invention is exactly treatment for above-mentioned scrotum pruritus due to damp pathogen and a kind of Chinese medicine formula proposed, and the medicine effect adopting this formula to prepare is good, instant effect.Be described in further detail below in conjunction with the specific embodiment of the present invention:
Embodiment 1:
A kind ofly treat externally-applied ointment of scrotum pruritus due to damp pathogen and preparation method thereof, each component of described externally-applied ointment and mass parts thereof are than as follows:
Radix Stemonae 12g, Radix Sophorae Flavescentis 8g, Rhizoma Atractylodis 12g, Fructus Cnidii 12g, Cortex Phellodendri (stir-fry) 12g, Fructus Forsythiae 15g, Cortex Pseudolaricis 12g, Flos Lonicerae 18g, Radix Saposhnikoviae 10g, Borneolum Syntheticum 0.25g, chlorhexidine acetate is appropriate, Mentholum is appropriate.
Embodiment 2:
A kind ofly treat externally-applied ointment of scrotum pruritus due to damp pathogen and preparation method thereof, each component of described externally-applied ointment and mass parts thereof are than as follows:
Radix Stemonae 13g, Radix Sophorae Flavescentis 9g, Rhizoma Atractylodis 13g, Fructus Cnidii 13g, Cortex Phellodendri (stir-fry) 13g, Fructus Forsythiae 17g, Cortex Pseudolaricis 13g, Flos Lonicerae 20g, Radix Saposhnikoviae 11g, Borneolum Syntheticum 0.30g, chlorhexidine acetate is appropriate, Mentholum is appropriate.
Embodiment 3:
A kind ofly treat externally-applied ointment of scrotum pruritus due to damp pathogen and preparation method thereof, each component of described externally-applied ointment and mass parts thereof are than as follows:
Radix Stemonae 15g, Radix Sophorae Flavescentis 10g, Rhizoma Atractylodis 15g, Fructus Cnidii 15g, Cortex Phellodendri (stir-fry) 15g, Fructus Forsythiae 20g, Cortex Pseudolaricis 15g, Flos Lonicerae 22g, Radix Saposhnikoviae 12g, Borneolum Syntheticum 0.35g, chlorhexidine acetate is appropriate, Mentholum is appropriate.
Model case:
Through clinical conditions scrotum pruritus due to damp pathogen patient totally 125 examples, the age is more than 27 years old 68 routine, only has 57 examples to be less than 27 years old.120 examples of fully recovering in 125 routine patients, effective 5 examples, total effective rate reaches 100%.After treatment, transference cure, disease obtains recovery from illness.

Claims (3)

1. treat an externally-applied ointment for scrotum pruritus due to damp pathogen, it is characterized in that, each component of described externally-applied ointment and mass parts thereof are than as follows:
The Radix Stemonae 5 ~ 15g, Radix Sophorae Flavescentis 3 ~ 10g, Rhizoma Atractylodis 7.5 ~ 15g, Fructus Cnidii 3 ~ 15g, Cortex Phellodendri (stir-fry) 7.5 ~ 15g, Fructus Forsythiae 16 ~ 20g, Cortex Pseudolaricis 5 ~ 15g, Flos Lonicerae 12 ~ 22g, Radix Saposhnikoviae 5 ~ 12g, Borneolum Syntheticum 0.15 ~ 0.35g, chlorhexidine acetate is appropriate, Mentholum is appropriate.
2. the externally-applied ointment for the treatment of scrotum pruritus due to damp pathogen according to claim 1, is characterized in that, each component of described externally-applied ointment and mass parts thereof are than as follows:
The Radix Stemonae 7 ~ 13g, Radix Sophorae Flavescentis 4 ~ 9g, Rhizoma Atractylodis 8 ~ 13g, Fructus Cnidii 4 ~ 13g, Cortex Phellodendri (stir-fry) 8 ~ 13g, Fructus Forsythiae 16 ~ 17g, Cortex Pseudolaricis 6 ~ 13g, Flos Lonicerae 13 ~ 20g, Radix Saposhnikoviae 6 ~ 11g, Borneolum Syntheticum 0.20 ~ 0.30g, chlorhexidine acetate is appropriate, Mentholum is appropriate.
3. according to the externally-applied ointment of the treatment scrotum pruritus due to damp pathogen described in claim 1 to 2, it is characterized in that, each component of described externally-applied ointment and mass parts thereof are than as follows:
Radix Stemonae 12g, Radix Sophorae Flavescentis 8g, Rhizoma Atractylodis 12g, Fructus Cnidii 12g, Cortex Phellodendri (stir-fry) 12g, Fructus Forsythiae 15g, Cortex Pseudolaricis 12g, Flos Lonicerae 18g, Radix Saposhnikoviae 10g, Borneolum Syntheticum 0.25g, chlorhexidine acetate is appropriate, Mentholum is appropriate.
CN201610000085.2A 2016-01-01 2016-01-01 External ointment for treating scrotal damp itch and preparation method for external ointment Pending CN105435038A (en)

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Application publication date: 20160330