CN105435013A - Traditional Chinese medicine enema powder used for treating chronic nonspecific ulcerative colitis, and preparation method thereof - Google Patents

Traditional Chinese medicine enema powder used for treating chronic nonspecific ulcerative colitis, and preparation method thereof Download PDF

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CN105435013A
CN105435013A CN201510958405.0A CN201510958405A CN105435013A CN 105435013 A CN105435013 A CN 105435013A CN 201510958405 A CN201510958405 A CN 201510958405A CN 105435013 A CN105435013 A CN 105435013A
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powder
ulcerative colitis
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朱林存
李婷
李金顺
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Abstract

The invention provides a traditional Chinese medicine enema powder used for treating chronic nonspecific ulcerative colitis. The traditional Chinese medicine enema powder is prepared from, by weight, 8 to 15 parts of smilax china L., 8 to 15 parts of radix sophorae flavescentis, 5 to 7 parts of indigo naturalis, 8 to 15 parts of herba portulacae, 3 to 5 parts of sanguis draxonis, 8 to 9 parts of herba euphorbiae humifusae, 6 to 9 parts of calcined alum, and 6 to 9 parts of pearl powder. The traditional Chinese medicine enema powder is prepared based on the principles of downward flow of damp-heat, stagnation of qi and blood stasis, and skin and external disease treatment; is prepared by taking the drug materials capable of clearing away heat and toxic materials, and promoting blood circulation to remove blood stasis as main raw materials, and drug materials capable of promoting tissue regeneration and astringing as auxiliary materials; and is capable of clearing dampness-heat and pathogenic toxin, activating blood qi, removing stasis, promoting generation of tissue, and curing anabrosis. Recurrence is avoided as far as possible, and the physiological functions of gastrointestinal tract are recovered.

Description

A kind of herbal enema powder for the treatment of chronic non-specific ulcerative colitis and preparation method thereof
Technical field
The present invention relates to the herbal enema powder for the treatment of chronic non-specific ulcerative colitis, also relate to the preparation method of herbal enema powder.
Background technology
Chronic non-specific ulcerative colitis, be called for short ulcerative colitis (ulcerative, UC) be a kind of inflammatory lesion mainly occurring in colonic mucosa layer, based on curing ulcer erosion, involve lower distal colon more, also can throughout whole colon, clinical main manifestations is stomachache, diarrhoea, tenesmus etc.UC is a kind of stubborn disease, easily recurs, and the course of disease is long.Modern disease Neo-Confucianism is thought, as recurrent exerbation, some pathological changes widely activeness case can concurrent ectocolon and colon cancer.This sick western medicine cause of disease is still not clear at present, pathogen and pathology of tcm determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs also disunity, therefore belongs to global problem.There is no specific medicament to primary disease treatment at present, western medical treatment is based on antibiotic, aminosallcylic acid, adrenocortical hormone, immune formulation, and its curative effect is not ideal enough, and relapse rate is very high, and side effect is large.Because UC easily recurs, need long-term prescription, side effect greatly just have impact on the use of chemicals.
Traditional prescription that current treatment by Chinese herbs UC many employings decoction is taken, general effect is undesirable, and the medicine played a major role in some Chinese medicinal formulaes such as Radix Aconiti Lateralis Preparata also has comparatively obvious toxic-side effects, and also has certain side effect to gastrointestinal tract.
Enema therapy can make medicine comprehensive engagement ulcer spot, through sick institute, promotes local absorption, gives full play to effect of antiinflammatory, hemostasis, detoxify, hold back wound, granulation promoting, clinical research finds that there are abundant tremulous pulse, vein, lymphatic plexus in the surrounding of rectum, and rectal mucosa has very strong absorption function.Retention-enema treatment, medicament mixed, in rectum juice, is absorbed by intestinal mucosa, transmits through following approach: (one) is directly absorbed by hemorrhoidal veins,middle, lower vein and anal veins and enters systemic circulation, because of without liver thus the head avoiding liver crosses antidotal effect, improve blood drug level; (2) enter liver by superior rectal vein trans-portal vein, after metabolism, participate in systemic circulation again; (3) rectum lymphsystem also absorption portion medicine.Article three, approach is all without harmonization of the stomach small intestinal, and avoid acid, alkali digestion enzyme to the impact of medicine and destruction, also alleviating medicine stimulates gastrointestinal, and thus bioavailability is increased to more than 80% by Treated in Retention Enema with Chinese Medicine.The traditional Chinese medical science is thought, large intestine comprises colon, caecum and rectum, its venation lung, with lung phase the exterior and the interior, and " convergence of vessels in the lung ", so by defeated in lung on passages through which vital energy circulates after the absorption of medicine per rectum, then by lung, medicine is transported to the vital organs of the human body, extremity bones of the body collectively.Per rectum retention-enema treatment can make medicine go directly disease institute, has again local thermotherapy to act on, and the one for the treatment of large intestine disease of can yet be regarded as is efficient, safety method; Unabsorbed powder can cover enteric cavity surface uniformly on the other hand, and maintains 5-6 hour, adsorbable multiple pathogens, is fixed in enteric cavity surface, then excretes with enterokinesia, thus avoid enterocyte to be damaged by pathogen, protect intestinal mucosa.Also fixing killing action is had to microorganisms such as escherichia coli, staphylococcus aureus, vibrio cholera, reduce the abnormal motion of enterocyte simultaneously, make the normal rhythm of recovery enterokinesia, safeguard conveying and the absorption function of intestinal, and the intercellular bridge of damage can be repaired, cell tight is connected, prevents pathogen from entering blood circulation.
Enema conventional at present has mesalazine enema, and it is fast that this medicine has curative effect mainly for UC acute stage, but the untoward reaction such as digestive system, central nervous system, anaphylaxis, hepatic and renal function injure are more, and expensive, and common patient is difficult to bear.And Chinese medicine decocting soup coloclysis is used for clinical treatment UC, required decoction dosage is large, and each groundwater increment is 15Oml-3OOml, patient's long-term perfusion, will stimulate intestinal mucosa, cause intestinal wall edema, medicinal liquid is not easily retained in enteric cavity, and treatment means is very inconvenient, affects the compliance of patient treatment.Due to the dialectical complexity of typing, curative effect is unstable, and preparation is preserved inconvenient, significantly limit the diagnosis and treatment of UC.
Summary of the invention
The technical problem to be solved in the present invention is to provide a kind of herbal enema powder for the treatment of chronic non-specific ulcerative colitis, plays the function of heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, promoting tissue regeneration by astringents, reduces the incidence of recurrences of chronic non-specific ulcerative colitis.
In order to solve the problems of the technologies described above, technical scheme of the present invention is:
Treat a herbal enema powder for chronic non-specific ulcerative colitis, composition and the weight of its crude drug are as follows:
Rhizoma Smilacis Chinensis 8 ~ 15 parts, Radix Sophorae Flavescentis 8 ~ 15 parts, Indigo Naturalis 5 ~ 7 parts, Herba Portulacae 8 ~ 15 parts, Sanguis Draxonis 3 ~ 5 parts, Herba Euphorbiae Humifusae 8 ~ 9 parts, dried Alumen 6 ~ 9 parts, Margarita powder 6 ~ 9 parts.
The herbal enema powder of above-mentioned treatment chronic non-specific ulcerative colitis, composition and the weight of its crude drug are as follows:
Rhizoma Smilacis Chinensis 12 ~ 15 parts, Radix Sophorae Flavescentis 12 ~ 15 parts, Indigo Naturalis 6 ~ 7 parts, Herba Portulacae 12 ~ 15 parts, Sanguis Draxonis 4 ~ 5 parts, Herba Euphorbiae Humifusae 8 ~ 9 parts, dried Alumen 7 ~ 9 parts, Margarita powder 7 ~ 9 parts.
The herbal enema powder of above-mentioned treatment chronic non-specific ulcerative colitis, composition and the weight of its crude drug are as follows:
Rhizoma Smilacis Chinensis 8 parts, Radix Sophorae Flavescentis 8 parts, Indigo Naturalis 5 parts, Herba Portulacae 8 parts, Sanguis Draxonis 3 parts, Herba Euphorbiae Humifusae 8 parts, dried Alumen 6 parts, Margarita powder 6 parts.
The herbal enema powder of above-mentioned treatment chronic non-specific ulcerative colitis, composition and the weight of its crude drug are as follows:
Rhizoma Smilacis Chinensis 15 parts, Radix Sophorae Flavescentis 15 parts, Indigo Naturalis 7 parts, Herba Portulacae 15 parts, Sanguis Draxonis 5 parts, Herba Euphorbiae Humifusae 9 parts, dried Alumen 9 parts, Margarita powder 9 parts.
The herbal enema powder of above-mentioned treatment chronic non-specific ulcerative colitis, composition and the weight of its crude drug are as follows:
Rhizoma Smilacis Chinensis 13 parts, Radix Sophorae Flavescentis 12 parts, Indigo Naturalis 6 parts, Herba Portulacae 12 parts, Sanguis Draxonis 4 parts, Herba Euphorbiae Humifusae 9 parts, dried Alumen 7 parts, Margarita powder 7 parts.
The herbal enema powder of above-mentioned treatment chronic non-specific ulcerative colitis, composition and the weight of its crude drug are as follows:
Rhizoma Smilacis Chinensis 10 parts, Radix Sophorae Flavescentis 13 parts, Indigo Naturalis 7 parts, Herba Portulacae 13 parts, Sanguis Draxonis 5 parts, Herba Euphorbiae Humifusae 8 parts, dried Alumen 9 parts, Margarita powder 9 parts.
The herbal enema powder of above-mentioned treatment chronic non-specific ulcerative colitis, composition and the weight of its crude drug are as follows:
Rhizoma Smilacis Chinensis 12 parts, Radix Sophorae Flavescentis 14 parts, Indigo Naturalis 7 parts, Herba Portulacae 8 parts, Sanguis Draxonis 3 parts, Herba Euphorbiae Humifusae 9 parts, dried Alumen 6 parts, Margarita powder 6 parts.
The technical problem to be solved in the present invention is to provide a kind of preparation method for the treatment of the herbal enema powder of chronic non-specific ulcerative colitis.
In order to solve the problems of the technologies described above, technical scheme of the present invention is:
A preparation method for the herbal enema powder of above-mentioned treatment chronic non-specific ulcerative colitis, concrete steps are as follows:
1), by Indigo Naturalis, Sanguis Draxonis, dried Alumen, Margarita powder give porphyrize powder respectively, cross 120 mesh sieves, for subsequent use;
2), by all the other crude drug through cleaning, oven dry, pulverizing, be ground into fine powder and cross 120 mesh sieves, for subsequent use;
3), by the weight of above-mentioned fine powder by each crude drug mix, then carry out sublevel segmentation cooling ripening sterilization treatment 20 ~ 30 minutes obtained powder.
The preparation method of the herbal enema powder of above-mentioned treatment chronic non-specific ulcerative colitis, sublevel segmentation cooling ripening sterilizing concrete steps are: temperature is raised to rapidly 110 DEG C, then segmentation is down to 100 DEG C.
Beneficial effect of the present invention is: we are according to damp invasion of lower energizer, stagnation of QI-blood, and the rule thirty years of age controlled with skin infection opinion, selects heat-clearing and toxic substances removing, the medicine of blood circulation promoting and blood stasis dispelling is main, is aided with the product of promoting tissue regeneration by astringents, makes Shi Re Bing Pian be able to clearly, vim and vigour are lived, the stasis of blood stagnantization, and new flesh is raw and ulcer heals.Slow down recurrence to greatest extent, recover gastrointestinal physiology function.
Detailed description of the invention
Treat a herbal enema powder for chronic non-specific ulcerative colitis, composition and the weight of its crude drug are as follows:
Rhizoma Smilacis Chinensis 8 ~ 15 parts, Radix Sophorae Flavescentis 8 ~ 15 parts, Indigo Naturalis 5 ~ 7 parts, Herba Portulacae 8 ~ 15 parts, Sanguis Draxonis 3 ~ 5 parts, Herba Euphorbiae Humifusae 8 ~ 9 parts, dried Alumen 6 ~ 9 parts, Margarita powder 6 ~ 9 parts.
In this formula, effect of each crude drug is as follows:
The Rhizoma Smilacis Chinensis adopted in Chinese medicine of the present invention, the growth of Rhizoma Smilacis Chinensis ethanol extraction to staphylococcus aureus, bacillus thuringiensis, escherichia coli and bacillus subtilis has inhibitory action, effectively can suppress Granuloma formation, effectively can suppress the increment of part tumor cell, extracorporeal platelet aggregation function can be suppressed.This medical instrument has expelling wind and removing dampness, the merit of removing toxicity for eliminating carbuncles.Cure mainly rheumatism, have loose bowels, dysentery, carbuncle sore tumefacting virus.
In the present invention, Radix Sophorae Flavescentis has removing damp-heat, the merit of parasite killing diuresis, for skin infection, dysentery, infusorian, skin scabies.Indigo Naturalis has heat-clearing and toxic substances removing, blood cooling and ecchymoses removing, the merit of pathogenic fire purging arresting convulsion.Herba Portulacae has the effect of heat-clearing and toxic substances removing, cooling blood for hemostasis, with controlling toxic-heat and blood stasis, having blood in stool.Sanguis Draxonis has promoting blood circulation to remove blood stasis, sore analgesic therapy, the effect of hemostasia and promoting granulation.Herba Euphorbiae Humifusae has astringing to arrest bleeding, controls the effect of dysentery antidiarrheal, for dysentery with red and white feces, has loose bowels.Dried Alumen has expectorant dampness, and antidiarrheal is stopped blooding, the merit of removing toxic substances parasite killing.Margarita powder has removing toxic substances heat clearing away, repercussive eliminating stagnation, and promoting tissue regeneration and ulcer healing, does not heal for ulcer, infections and not hold back and can coordinating the actions of various ingredients in a prescription.
The concrete formula of one of the present invention is, composition and the weight of its crude drug are as follows:
Rhizoma Smilacis Chinensis 12 ~ 15 parts, Radix Sophorae Flavescentis 12 ~ 15 parts, Indigo Naturalis 6 ~ 7 parts, Herba Portulacae 12 ~ 15 parts, Sanguis Draxonis 4 ~ 5 parts, Herba Euphorbiae Humifusae 8 ~ 9 parts, dried Alumen 7 ~ 9 parts, Margarita powder 7 ~ 9 parts.
The concrete formula of one of the present invention is, composition and the weight of its crude drug are as follows:
Rhizoma Smilacis Chinensis 8 parts, Radix Sophorae Flavescentis 8 parts, Indigo Naturalis 5 parts, Herba Portulacae 8 parts, Sanguis Draxonis 3 parts, Herba Euphorbiae Humifusae 8 parts, dried Alumen 6 parts, Margarita powder 6 parts.
The concrete formula of one of the present invention is, composition and the weight of its crude drug are as follows:
Rhizoma Smilacis Chinensis 15 parts, Radix Sophorae Flavescentis 15 parts, Indigo Naturalis 7 parts, Herba Portulacae 15 parts, Sanguis Draxonis 5 parts, Herba Euphorbiae Humifusae 9 parts, dried Alumen 9 parts, Margarita powder 9 parts.
The concrete formula of one of the present invention is, composition and the weight of its crude drug are as follows:
Rhizoma Smilacis Chinensis 13 parts, Radix Sophorae Flavescentis 12 parts, Indigo Naturalis 6 parts, Herba Portulacae 12 parts, Sanguis Draxonis 4 parts, Herba Euphorbiae Humifusae 9 parts, dried Alumen 7 parts, Margarita powder 7 parts.
The concrete formula of one of the present invention is, composition and the weight of its crude drug are as follows:
Rhizoma Smilacis Chinensis 10 parts, Radix Sophorae Flavescentis 13 parts, Indigo Naturalis 7 parts, Herba Portulacae 13 parts, Sanguis Draxonis 5 parts, Herba Euphorbiae Humifusae 8 parts, dried Alumen 9 parts, Margarita powder 9 parts.
The concrete formula of one of the present invention is, composition and the weight of its crude drug are as follows:
Rhizoma Smilacis Chinensis 12 parts, Radix Sophorae Flavescentis 14 parts, Indigo Naturalis 7 parts, Herba Portulacae 8 parts, Sanguis Draxonis 3 parts, Herba Euphorbiae Humifusae 9 parts, dried Alumen 6 parts, Margarita powder 6 parts.
Ulcerative colitis belongs to that the traditional Chinese medical science " is had loose bowels ", " dysentery ", " hemorrhoidal hamorrhage ", " pain is rushed down ", " intestinal Bleach ", the category such as " stomachache ".Motherland's medical literature has again the appellation such as " duck is half congealed ", " lientery ", " watery diarrhea ", " pouring down ", " lower profit ".Theory of Chinese medical science is thought, dysfunction of the spleen in transportation, damp and hot heresy pent up large intestine, causes enteral stagnation of QI-blood to be the pathologic basis of primary disease.Various paathogenic factor causes taste impaired, failing of the spleen to transport, damp and hot interior life, then large intestine of betting, and visceral-qi stops up resistance, and with the passing of time stagnation of QI-blood damp and hot, unclear, steams corruption, and see and have loose bowels, and red white pus, damp pathogen being sticky and stagnant in nature is deep, therefore primary disease is how prolonged touching, recurrent exerbation.We are according to damp invasion of lower energizer, stagnation of QI-blood, the rule thirty years of age controlled with skin infection opinion, and select heat-clearing and toxic substances removing, the medicine of blood circulation promoting and blood stasis dispelling is main, is aided with the product of promoting tissue regeneration by astringents, makes Shi Re Bing Pian be able to clearly, and vim and vigour are lived, the stasis of blood stagnantization, and new flesh is raw and ulcer heals.Slow down recurrence to greatest extent, recover gastrointestinal physiology function.
The crude drug that the present invention adopts is Chinese medicine common on market, and pharmacy is easy, cheap, Chinese medicine of the present invention, according to the pathogeny of UC, various paathogenic factor causes taste impaired, failing of the spleen to transport, damp and hot interior life, then large intestine of betting, visceral-qi stops up resistance, and with the passing of time stagnation of QI-blood damp and hot, unclear, steam corruption, and see and have loose bowels, red white pus, dampneee being viscous and lingering is deep, prolonged touching, recurrent exerbation.The present invention is according to damp invasion of lower energizer, stagnation of QI-blood, the rule thirty years of age controlled with skin infection opinion, and select heat-clearing and toxic substances removing, the medicine of blood circulation promoting and blood stasis dispelling is main, is aided with the product of promoting tissue regeneration by astringents, makes Shi Re Bing Pian be able to clearly, and vim and vigour are lived, the stasis of blood stagnantization, and new flesh is raw and ulcer heals.Side effect of the present invention is little, not easily recurs after recovery from illness, and curative effect is fast.
The preparation method of the herbal enema powder for the treatment of chronic non-specific ulcerative colitis, concrete steps are as follows:
1), by Indigo Naturalis, Sanguis Draxonis, dried Alumen, Margarita powder give porphyrize powder respectively, cross 120 mesh sieves, for subsequent use;
2), by all the other crude drug through cleaning, oven dry, pulverizing, be ground into fine powder and cross 120 mesh sieves, for subsequent use;
3), by the weight of above-mentioned fine powder by each crude drug mix, then carry out sublevel segmentation cooling ripening sterilization treatment 20 ~ 30 minutes obtained powder.
By powder bag distribution packaging, 10 grams every bag, 30 bags is a course for the treatment of, and sealing is preserved.
Preferably, sublevel segmentation cooling ripening sterilizing concrete steps are: temperature is raised to rapidly 110 DEG C, then segmentation is down to 100 DEG C.
The using method of the herbal enema powder for the treatment of chronic non-specific ulcerative colitis:
Get powder 1 and wrap heavy 10g, give boiled water 100ml and wash open, load in disposable enemator when putting temperature about about 37 DEG C, get left lateral position and to go down on one's knees hip in the wrong, about 5-10 centimetre in anus is inserted in enemator front end, slowly instills intestinal (about 60-80 drips/min).Be transformed to KCP 15min after coloclysis, after be transformed to right arm reclining 15min, then be transformed to lie low rest, not out-of-bed activity, every night coloclysis 1 time just before going to bed, should emptying stool before coloclysis.Within 4 weeks, be 1 course for the treatment of, generally use 2 ~ 3 courses for the treatment of.
The present invention plays the function of heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, promoting tissue regeneration and ulcer healing, and reduce the incidence of recurrences of UC, owing to being prepared by the material of pure natural, be free from side effects, expense is lower, can improve patient compliance like this, alleviate patient economy burden.
Case 1:
Zhang, man, 47 years old, nearly 10 years of bloody purulent stool stomachache recurrent exerbation, goes to a doctor in Duo Jia hospital, takes mesalazine curative effect and do not show, take Chinese medicine decoction and have no effective half a year, give 1 course for the treatment of of this medicine enema treatment, bloody purulent stool disappears, stomachache alleviates, and uses 3 courses for the treatment of, stool rule, every day 1 ~ 2 time, without pus and blood, just soft shaping, colic symptoms disappears, and fecal occult blood is negative.Follow up a case by regular visits to 4 years, without recurrence.
Case 2:
Hu, female, 51 years old, soft stools, every day 3 ~ 5 times, normal attachment mucus and pus and blood, medical history about 6 years, row electronic colonoscopy is shown in that sigmoid colon, rectum are extensively rotten to the corn, hemorrhage, pathologic finding: find crypt abscess, meet ulcerative colitis, take balsalazide sodium preparation effective, but still recurrent exerbation, use 2 courses for the treatment of of medicine of the present invention, stool is shaped, bloody purulent stool disappears, and just routine is shown in a little leukocyte, and erythrocyte is accidental, 1 course for the treatment of of after treatment, stool rule, is just shaped, without mucus, just conventional normal, follow up a case by regular visits to and have no recurrence in 2 years.
Case 3:
High certain, man, 36 years old, just before, stomachache is uncomfortable, morning diarrhea 2 ~ 3 times, every day defecation 5 times, just mucus is had in, time have sanguinopurulent just, medical history 3 years, colonoscopy is shown in that descending colon to rectum is shown in that multiple ulcer is rotten to the corn, mucosa edema, pathologic finding is repeatedly all pointed out and is met ulcerative colitis, multi-treatment effect is not good, use 2 courses for the treatment of of medicine of the present invention, stool rule, every day 1 time, occasionally there are 2 times, stomachache disappears, just routine is shown in a little leukocyte, without erythrocyte, 2 courses for the treatment of of after treatment, stool is shaped, just conventional normal, colonoscopy is shown in that finding Colorectal mucosa is Chinese red, vascular lake is clear, change without rotten to the corn and ulcer, postcolon mirror check in 3 years is without exception.
Case 4:
High certain, female, 32 years old, civil servant, diarrhoea, mucus just 2 years, often with sanguinopurulent thing, takes antibiotic therapy invalid certainly, take GUCHANG ZHIXIE WAN unsatisfactory curative effect, enteroscopy total colectomy, rectal mucosa edema, is dispersed in petechia, erosion, just routine examination finds leukocyte +++, erythrocyte ++, use 1 course for the treatment of of this medicine, stool is shaped, every day 1 time, just conventional erythrocyte+, leukocyte+, continue use and recover normal completely 1 course for the treatment of, it is without exception to follow up a case by regular visits to colonoscopy in 1 year.
Case 5:
Lee, man, 76 years old, bloody purulent stool is interrupted outbreak 10 years, repeatedly row electronic colonoscopy is diagnosed as ulcerative colitis, every day defecation 6 ~ 8 times, cause anemia come institute because arranging a large amount of pus and blood more than 10 sky, give reptilase intramuscular injection, transfuse blood 800 milliliters, conventional electrolyte supplement and to maintain in body the Supporting Therapys such as acid-base balance, give this medicine enema treatment simultaneously, hemorrhage minimizing after being admitted to hospital 3 days, stop Western medicine, simple use Chinese medicine of the present invention, after 10 days, symptom is obviously improved, just secondary every day 2 ~ 3 times, pus and blood obviously reduces, systemic conditions takes a turn for the better, be used in conjunction 1 course for the treatment of, just without pus and blood and mucus in, just routine still visible red, leukocyte, continue 2 courses for the treatment of of use, stool is shaped, every day 1 ~ 2 time, without mucus and pus and blood, just conventional no abnormality seen, clinical cure, patient requests continues to strengthen treatment, continuous with 2 courses for the treatment of, follow up a case by regular visits to 2 years, without recurrence.
Case 6:
Wang, female, 57 years old, soft stools, was shown in pus and blood every day 3 ~ 5 times just, medical history half a year, and colonoscopy is shown in that sigmoid colon, rectum are extensively rotten to the corn, multiple fester, and pathological biopsy confirms to meet nonspecific ulcerative mucosal inflammation.Use medicine of the present invention 10 days, bloody purulent stool reduces, just secondary minimizing, continues use 20 days, stool rule, every day 1 ~ 2 time, and without bloody purulent stool, just conventional normal, within rear 3 months, colonoscopy is without exception.
Case 7:
The Meng, female, 59 years old, defecate shapeless, every day 4 ~ 7 times, normal companion's abdominal pain is uncomfortable, be very with umbilicus week, time serious just in see kermesinus blood and mucus, medical history about 10 years, take the Chinese and western drugses such as all kinds of antibiotic, hemorrhage, Salicylic Acid Formulations without improvement throughout the year, repeatedly, and pathologic finding is all pointed out and is met nonspecific inflammation in colonoscopy, after using 3 courses for the treatment of of this medicine, stool recovers normal completely, and colonoscopy intestinal mucosa is normal.
Case 8:
Liu, female, 49 years old, office worker, diarrhoea mucus hemafecia 2 years, all pain of umbilicus just, colonoscopy sigmoid colon hypomere and rectal mucosa hyperemia, edema is rotten to the corn, multiple petechia, uses 2 courses for the treatment of of this medicine, defecation rule, every day 1 ~ 2 time, deliquescing is shaped, and just red, the leukocyte of routine examination is feminine gender, follow-up 3 years, does not recur again.

Claims (9)

1. treat a herbal enema powder for chronic non-specific ulcerative colitis, it is characterized in that, composition and the weight of its crude drug are as follows:
Rhizoma Smilacis Chinensis 8 ~ 15 parts, Radix Sophorae Flavescentis 8 ~ 15 parts, Indigo Naturalis 5 ~ 7 parts, Herba Portulacae 8 ~ 15 parts, Sanguis Draxonis 3 ~ 5 parts, Herba Euphorbiae Humifusae 8 ~ 9 parts, dried Alumen 6 ~ 9 parts, Margarita powder 6 ~ 9 parts.
2. the herbal enema powder for the treatment of chronic non-specific ulcerative colitis according to claim 1, is characterized in that, composition and the weight of its crude drug are as follows:
Rhizoma Smilacis Chinensis 12 ~ 15 parts, Radix Sophorae Flavescentis 12 ~ 15 parts, Indigo Naturalis 6 ~ 7 parts, Herba Portulacae 12 ~ 15 parts, Sanguis Draxonis 4 ~ 5 parts, Herba Euphorbiae Humifusae 8 ~ 9 parts, dried Alumen 7 ~ 9 parts, Margarita powder 7 ~ 9 parts.
3. the herbal enema powder for the treatment of chronic non-specific ulcerative colitis according to claim 1, is characterized in that, composition and the weight of its crude drug are as follows:
Rhizoma Smilacis Chinensis 8 parts, Radix Sophorae Flavescentis 8 parts, Indigo Naturalis 5 parts, Herba Portulacae 8 parts, Sanguis Draxonis 3 parts, Herba Euphorbiae Humifusae 8 parts, dried Alumen 6 parts, Margarita powder 6 parts.
4. the herbal enema powder for the treatment of chronic non-specific ulcerative colitis according to claim 1, is characterized in that, composition and the weight of its crude drug are as follows:
Rhizoma Smilacis Chinensis 15 parts, Radix Sophorae Flavescentis 15 parts, Indigo Naturalis 7 parts, Herba Portulacae 15 parts, Sanguis Draxonis 5 parts, Herba Euphorbiae Humifusae 9 parts, dried Alumen 9 parts, Margarita powder 9 parts.
5. the herbal enema powder for the treatment of chronic non-specific ulcerative colitis according to claim 1, is characterized in that, composition and the weight of its crude drug are as follows:
Rhizoma Smilacis Chinensis 13 parts, Radix Sophorae Flavescentis 12 parts, Indigo Naturalis 6 parts, Herba Portulacae 12 parts, Sanguis Draxonis 4 parts, Herba Euphorbiae Humifusae 9 parts, dried Alumen 7 parts, Margarita powder 7 parts.
6. the herbal enema powder for the treatment of chronic non-specific ulcerative colitis according to claim 1, is characterized in that, composition and the weight of its crude drug are as follows:
Rhizoma Smilacis Chinensis 10 parts, Radix Sophorae Flavescentis 13 parts, Indigo Naturalis 7 parts, Herba Portulacae 13 parts, Sanguis Draxonis 5 parts, Herba Euphorbiae Humifusae 8 parts, dried Alumen 9 parts, Margarita powder 9 parts.
7. the herbal enema powder for the treatment of chronic non-specific ulcerative colitis according to claim 1, is characterized in that, composition and the weight of its crude drug are as follows:
Rhizoma Smilacis Chinensis 12 parts, Radix Sophorae Flavescentis 14 parts, Indigo Naturalis 7 parts, Herba Portulacae 8 parts, Sanguis Draxonis 3 parts, Herba Euphorbiae Humifusae 9 parts, dried Alumen 6 parts, Margarita powder 6 parts.
8. a preparation method for the herbal enema powder of the arbitrary described treatment chronic non-specific ulcerative colitis of claim 1-7, it is characterized in that, concrete steps are as follows:
1), by Indigo Naturalis, Sanguis Draxonis, dried Alumen, Margarita powder give porphyrize powder respectively, cross 120 mesh sieves, for subsequent use;
2), by all the other crude drug through cleaning, oven dry, pulverizing, be ground into fine powder and cross 120 mesh sieves, for subsequent use;
3), by the weight of above-mentioned fine powder by each crude drug mix, then carry out sublevel segmentation cooling ripening sterilization treatment 20 ~ 30 minutes obtained powder.
9. the preparation method of the herbal enema powder for the treatment of chronic non-specific ulcerative colitis according to claim 8, is characterized in that: sublevel segmentation cooling ripening sterilizing concrete steps are: temperature is raised to rapidly 110 DEG C, then segmentation is down to 100 DEG C.
CN201510958405.0A 2015-12-21 2015-12-21 Traditional Chinese medicine enema powder used for treating chronic nonspecific ulcerative colitis, and preparation method thereof Pending CN105435013A (en)

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