CN105434900A - Traditional Chinese medicine composition for dispelling wind, activating blood, dissipating cold, and relieving pain and preparation method thereof - Google Patents

Traditional Chinese medicine composition for dispelling wind, activating blood, dissipating cold, and relieving pain and preparation method thereof Download PDF

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Publication number
CN105434900A
CN105434900A CN201510954391.5A CN201510954391A CN105434900A CN 105434900 A CN105434900 A CN 105434900A CN 201510954391 A CN201510954391 A CN 201510954391A CN 105434900 A CN105434900 A CN 105434900A
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parts
chinese medicine
hippocampus
medicine composition
relieving pain
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Inventor
吕姗姗
陈犁
陈云
刘勇
周年华
陈晓雪
谯志文
唐桂英
杨超
涂雪令
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CHONGQING HILAN PHARMACEUTICAL Co Ltd
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CHONGQING HILAN PHARMACEUTICAL Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/898Orchidaceae (Orchid family)
    • A61K36/8988Gastrodia
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    • A61K31/125Camphor; Nuclear substituted derivatives thereof
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    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286Carthamus (distaff thistle)
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/47Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
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    • A61K36/18Magnoliophyta (angiosperms)
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    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/714Aconitum (monkshood)
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/732Chaenomeles, e.g. flowering quince
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    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
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    • A61K2236/51Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying

Abstract

The invention provides a traditional Chinese medicine composition for dispelling wind, activating blood, dissipating cold, and relieving pain. The composition is mainly composed of the following components: unprocessed semen strychni, safflower, pawpaw, licorice, rhizoma gastrodiae, hippocampus, borneol, rhizoma belamcandae, angelica pubescens, Chinese magnoliavine, cassia bark, camphor, artificial musk, radix aconiti agrestis, buck grass, speranskia herb, and methyl salicylate. The preparation method comprises the following steps: grinding hippocampus, decocting hippocampus to obtain liquid decoction, grinding unprocessed semen strychni, safflower, pawpaw, licorice, rhizoma gastrodiae, rhizoma belamcandae, angelica pubescens, Chinese magnoliavine, cassia bark, radix aconiti agrestis, buck grass, and speranskia herb, mixing the powder with residual hippocampus, carrying out percolation to obtain percolate, condensing the percolate; merging the condensed percolate and liquid decoction, condensing the mixture to obtain extract, and finally mixing the extract with artificial musk, borneol, methyl salicylate, and camphor. The provided traditional Chinese medicine composition has the advantages of mild medicinal property, simple composition, easily available raw material, good effect on dispelling wind, activating blood, dissipating cold, and reliving pain, and no relapse.

Description

A kind of Chinese medicine composition for pathogenic wind expelling and blood circulation promoting, dispersing cold for relieving pain and preparation method thereof
Technical field
The present invention relates to the field of Chinese medicines, in particular to a kind of Chinese medicine composition for pathogenic wind expelling and blood circulation promoting, dispersing cold for relieving pain and preparation method thereof.
Background technology
Along with modern society's rhythm is accelerated gradually; people due to life, work aspect pressure often can feel tired sleepiness; especially the job demand of working clan is long-term is sitting in office handles official business in the face of computer, for a long time; therefore; working clan the most easily feels fatigue due to professionalism; in the course of time, the commonly encountered diseases such as the rheumatoids such as rheumatic lumbago and skelalgia, lumbar muscle strain, scapulohumeral periarthritis and arthralgia disease can easily be caused.
These diseases once must on be difficult to root, the simple and easy conventional methods such as the remorse treatment of massage treatment, pin, closed treating, functional exercise can only be relied on to slow down the state of an illness, especially very fast good therapeutic effect is had to slight patient, but to severe patient and really is effective, often the initial stage takes effect, but cure the symptoms, not the disease, easily recur.
For a long time, people find always can have significance effect loose wind damp eliminating, promoting blood circulation and stopping pain method occur, and cure after can not also recur.
In view of this, special proposition the present invention.
Summary of the invention
The first object of the present invention is to provide a kind of Chinese medicine composition for pathogenic wind expelling and blood circulation promoting, dispersing cold for relieving pain, described Chinese medicine composition has that property of medicine gentleness, assembly are simple, raw material is easy to get, and the advantage such as can not to recur after, recovery from illness effective for pathogenic wind expelling and blood circulation promoting, dispersing cold for relieving pain.
The second object of the present invention is to provide a kind of preparation method of the described Chinese medicine composition for pathogenic wind expelling and blood circulation promoting, dispersing cold for relieving pain, and preparation method has can the active ingredient of complete reservation medicine, and has method and be simply easy to the advantages such as operation.
In order to realize above-mentioned purpose of the present invention, spy by the following technical solutions:
Embodiments provide a kind of Chinese medicine composition for pathogenic wind expelling and blood circulation promoting, dispersing cold for relieving pain, it is made primarily of following raw material: in mass fraction, Semen Strychni 100-400 part, Flos Carthami 10-40 part, Fructus Chaenomelis 10-40 part, Radix Glycyrrhizae 10-40 part, Rhizoma Gastrodiae 10-40 part, Hippocampus 2-8 part, Borneolum Syntheticum 2-10 part, Rhizoma Belamcandae 1-8 part, Radix Angelicae Pubescentis 2-8 part, Fructus Schisandrae Chinensis 1-15 part, Cortex Cinnamomi 5-20 part, Camphora 10-40 part, artificial Moschus 0.5-5 part, Radix Aconiti Kusnezoffii 1-10 part, Herba Lycopodii 2-20 part, Herba speranskiae tuberculatae 2-20 part, methyl salicylate 10-40 part.
In prior art, the medicine for pathogenic wind expelling and blood circulation promoting, dispersing cold for relieving pain sold on the market emerges in an endless stream, but these medicines are cured the symptoms, not the disease mostly, temporarily can only reach the effect that alleviating pain is invigorated blood circulation, and is easy to recurrence after recovery from illness.The present invention is in order to conscientiously solve the technical problem of above appearance, provide a kind of Chinese medicine composition for pathogenic wind expelling and blood circulation promoting, dispersing cold for relieving pain, can be good at pathogenic wind expelling and blood circulation promoting, dispersing cold for relieving pain, for the patient that the state of an illness is heavier, the time of some months also can fully recover, and has no side effect, and also can not recur after curing again, the diseases such as especially meciless for soreness of waist pain, extremity and wind-cold syndrome and numbness have good curative effect, and some rheumatoid class diseases of scapulohumeral periarthritis also have special effect in addition.
The proportioning of each component in raw material of the present invention all has certain control, drug effect due to Chinese medicine needs each component mutual 5 to be equipped with to achieve the goal, if therefore arbitrarily component is measured its drug effect excessive and is reached peak, add also unhelpful again, and very few its drug effect that do not make on the contrary added gives full play of, therefore suitable proportioning seems particularly important.Chinese medicine composition of the present invention can reach symptom management, so that the object of long-term treatment, is also conducive to regulating physical ability simultaneously, the system caused due to the state of an illness avoiding patient regular is bad, adjustment health can be played, effect of health care, and then the effect reaching disease therapy.
In the present invention, Semen Strychni nature and flavor are bitter, cold, return liver, spleen channel, have relaxing muscles and tendons to promote blood circulation, effect of cold expelling dredging collateral.For traumatic injury, ulcer sore pain has good curative effect.Semen Strychni also has except rheumatism, and effect of cold-dispelling, has good effect for rheumatic and rheumatoid arthritis.General addition is 100-400 part, and more excellent is 150-250 part, and optimum is 200 parts, can also select 120 parts, 180 parts or 300 parts etc.
Flos Carthami is warm in nature, acrid in the mouth, latus rectum of invigorating blood circulation, eliminating stasis to stop pain.For amenorrhea, dysmenorrhea, lochia, lump in the abdomen mass in the abdomen, traumatic injury.Be suitable for various varicosis, peripheral neuritis, blood circulation is bad, lower limb numbness or the congestion such as livid purple.General addition is 10-40 part, and more excellent is 20-30 part, and optimum is 25 parts, can also select 15 parts, 22 parts or 35 parts etc.
Fructus Chaenomelis is warm in nature, sour in the mouth, enters liver, spleen channel, has and help digestion, anthelmintic, heat clearing away, the effect of dispeling the wind.General addition is 10-40 part, and more excellent is 20-30 part, and optimum is 25 parts, can also select 15 parts, 22 parts or 35 parts etc.
The flat sweet in the mouth of Radix Glycyrrhizae property, has removing toxic substances, eliminates the phlegm, pain relieving, spasmolytic is so that the pharmacological action such as anticancer.In the traditional Chinese medical science, Radix Glycyrrhizae invigorating the spleen and replenishing QI, grows and coughs lung moistening, and emergency is detoxified, and is in harmonious proportion hundred medicines.Clinical practice divides, and " life is used " is not with " processed with honey ".Raw with curing mainly laryngopharynx swelling and pain, cellulitis skin infection, gastrointestinal ulceration and solution poison of drug, alimentary toxicosis etc., processed with honey cures mainly spleen and stomach function and goes down, and large loose stool is thin, weak heating and cough, cardiopalmus etc.General addition is 10-40 part, and more excellent is 20-30 part, and optimum is 25 parts, can also select 15 parts, 22 parts or 35 parts etc.
Rhizoma Gastrodiae sweet in the mouth, property are flat, enter Liver Channel, suppressing the hyperactive liver to relieve the wind syndrome relieving convulsion.Dizzy for having a headache, numb limbs and tense tendons, infantile convulsion, epilepsy clonus, tetanus.General addition is 10-40 part, and more excellent is 20-30 part, and optimum is 25 parts, can also select 15 parts, 22 parts or 35 parts etc.
Hippocampus is the rare Chinese medicine that a kind of economic worth is higher, there is the medicinal functions such as building body, kidney invigorating and YANG supporting, relaxing muscles and tendons and activating QI and blood in the collateral, anti-inflammatory analgetic, tranquillizing and allaying excitement, relieving cough and asthma, particularly more effective for the neural disease for the treatment of, enjoy the favor of people since ancient times.In all raw medicinal materials, Hippocampus role is maximum, Chinese medicine composition of the present invention just can be made to have good curative effect just because of it exists as extra conductant ingredient, therefore the specific selection of visible Hippocampus is extremely important, in addition due to it is famousr and precious and institute carry dose drug effect comparatively greatly, need the dosage that control is suitable.Its general addition is 2-8 part, and more excellent is 3-6 part, and optimum is 5 parts, can also select 2.5 parts, 4 parts or 7 parts etc.
Borneolum Syntheticum acrid in the mouth, hardship, cold nature.There is the function of refreshment of having one's ideas straightened out, clearing heat for detumescence, pain relieving.Mainly contain antibacterial, antiinflammatory, analgesic effect etc.General addition is 2-10 part, and more excellent is 3-8 part, and optimum is 6 parts, can also select 2.5 parts, 5 parts or 8.5 parts etc.
Rhizoma Belamcandae bitter in the mouth, cold in nature, enter lung, Liver Channel.There are resolving toxin and disinhibiting the throat, removing heat-phlegm, heat radiation disappears the effect tied.General addition is 1-8 part, and more excellent is 2-6 part, and optimum is 5 parts, can also select 3 parts, 4 parts or 6.5 parts etc.
Radix Angelicae Pubescentis has antiinflammatory, analgesia and sedation, has inhibitory action to platelet aggregation.General addition is 2-8 part, and more excellent is 3-6 part, and optimum is 5 parts, can also select 2.5 parts, 4 parts or 7 parts etc.
Fructus Schisandrae Chinensis sweet in the mouth, acid, warm in nature.Energy supplementing QI for promoting the production of body fluid, the kidney invigorating is nourished heart, and restrains astringent or styptic treatment for spontaneous sweating.General addition is 1-15 part, and more excellent is 3-10 part, and optimum is 6 parts, can also select 2 parts, 4 parts or 10 parts etc.
Cortex Cinnamomi acrid in the mouth, sweet, hot greatly, return kidney, spleen, the heart, Liver Channel.Mend fire supporing yang, let the fire back to its origin, dispersing cold for relieving pain, promoting blood circulation to restore menstrual flow.For sexual impotence, cold womb, trusted subordinate's cold type of pain, deficiency and coldness vomiting and diarrhoea, amenorrhea, dysmenorrhea, warming the meridian and promoting blood circulation.General addition is 5-20 part, and more excellent is 8-15 part, and optimum is 12 parts, can also select 6 parts, 10 parts or 18 parts etc.
Camphora has orifice opening, qi stagnation removing, wards off foul, killing parasites for relieving itching, reducing swelling and alleviating pain effect, cures mainly the symptoms such as scabies pruritus, traumatic pain, toothache.General addition is 10-40 part, and more excellent is 20-30 part, and optimum is 25 parts, can also select 15 parts, 22 parts or 35 parts etc.
The pungent temperature of Moschus, QI exhaustion is fragrant, and the property of walking to alter is very strong, and having extremely strong refreshment effect of having one's ideas straightened out, is the good medicine of refreshment, the most applicable excess syndrome of stroke coma symptom, no matter constipation due to cold pathogen, heat-blockage, with all imitate.General addition is 0.5-5 part, and more excellent is 2-4 part, and optimum is 3 parts, can also select 1 part, 2.5 parts or 4.5 parts etc.
The effects such as Radix Aconiti Kusnezoffii has dispersing cold for relieving pain, opens expectorant, detumescence, cure mainly anemofrigid-damp arthralgia, paralysis due to windstroke, tetanus, wind syndrome of head, sore throat, carbuncle, furuncle etc.General addition is 1-10 part, and more excellent is 2-8 part, and optimum is 5 parts, can also select 3 parts, 4.5 parts or 6 parts etc.
Herba Lycopodii has the effect such as expelling wind and cold, dehumidifying detumescence, relaxing muscles and tendons to promote blood circulation, and has certain hypotensive effect.General addition is 2-20 part, and more excellent is 4-15 part, and optimum is 10 parts, can also select 3 parts, 12 parts or 18 parts etc.
Herba speranskiae tuberculatae has expelling wind and removing dampness, relaxing muscles and tendons and activating QI and blood in the collateral, the effects such as promoting blood circulation and stopping pain.General addition is 2-20 part, and more excellent is 4-15 part, and optimum is 10 parts, can also select 3 parts, 12 parts or 18 parts etc.
Methyl salicylate has another name called wintergreen oil, colourless to weak yellow liquid, and have the special odor of medicinal herbs, taste is sweet and peppery, has local irritant effect, can promote local blood circulation.Be mainly used in spraining, dampen, lumbago, myalgia, neuralgia, antipruritic etc.General addition is 10-40 part, and more excellent is 20-30 part, and optimum is 25 parts, can also select 15 parts, 22 parts or 35 parts etc.
As can be seen from effect of above-mentioned each medical material, although the drug effect of ingredients own is more extensive, but in view of the monarch and his subjects' compatibility relationship between Chinese medicine, inventor picks these tens kinds of medical materials except valuing the drug effect of its medical material itself from thousands upon thousands medical materials, also be mutual 5 join after reach drug effect strengthen effect, therefore consumption and adding proportion need great care, if the excessive medicine that may make of addition itself has certain poison pair property done, if the too small drug effect not reaching expection of dosage, also want the conventional addition of reference drug itself in addition, optimum addition finally could be determined through many-sided considering, can not select just can to know compatibility relationship by simple, need through a large amount of practice.Chinese medicine composition of the present invention not only possesses the function of pathogenic wind expelling and blood circulation promoting, dispersing cold for relieving pain, effectively can also nurse one's health the every function of human body, tool improves effect of immunity, building body, enhance human body constitution and also just reduce Expectancy accordingly, Be very effective.Put into practice by many-side on the addition of each crude drug finally determined, Semen Strychni is larger compared with the dosage of other raw materials, but designing dosage is like this that what to have certain reason is not simple arbitrarily to add, the scheme disclosed in strict accordance with the present invention is needed to add, if dosage may not reach the object of pathogenic wind expelling and blood circulation promoting, dispersing cold for relieving pain not at all, or just temporarily maintain drug effect, can not reach the object of longlasting treatments, therefore addition needs great care.Product of the present invention is natural Chinese herbal medicine of drawing materials in addition, has no side effect.The ammonia nitrogen discharge etc. to environment can be reduced after using, reduce environmental pollution, to the mankind and environmentally friendly, environmental protection.
The embodiment of the present invention, except providing the Chinese medicine composition of a kind of pathogenic wind expelling and blood circulation promoting, dispersing cold for relieving pain, additionally provides an its preparation method, comprises the steps:
Hippocampus is pulverized and decocts to obtain decocting liquid, for subsequent use;
After Semen Strychni, Flos Carthami, Fructus Chaenomelis, Radix Glycyrrhizae, Rhizoma Gastrodiae, Rhizoma Belamcandae, Radix Angelicae Pubescentis, Fructus Schisandrae Chinensis, Cortex Cinnamomi, Radix Aconiti Kusnezoffii, Herba Lycopodii, Herba speranskiae tuberculatae are pulverized and mixed with the remaining Hippocampus of decoction, percolation obtains percolate, concentrated;
Percolate after concentrated and described decocting liquid are merged and are condensed into extractum, and mix with artificial Moschus, Borneolum Syntheticum, methyl salicylate, Camphora.
As can be seen from the preparation method of the embodiment of the present invention, this taste medical material of Hippocampus specially decocts separately by the present invention, and remaining Hippocampus residue is not directly abandon after decocting, also need to be used in subsequent step, such design operation route is used in order that fully refined by the effective ingredient in Hippocampus, its drug effect is performed to ultimate attainment, be not simply each raw medicinal material mixing is decocted, percolation just can realize the solution of the present invention, the cooperation raw material of the present invention of certain routine also can have pathogenic wind expelling and blood circulation promoting, the effect of dispersing cold for relieving pain, but preparation method of the present invention makes the effect of product more to rise a step.
It should be noted that in addition, in preparation method of the present invention, the charging sequence of raw material also has requirement, artificial Moschus, Borneolum Syntheticum, methyl salicylate, this several medical material of Camphora are wanted finally just to add, such restriction is also determine according to the different in kind of various medical material itself, and therefore order of addition will operate in strict accordance with the solution of the present invention.
Wherein, Hippocampus is pulverized the number of times decocted and preferably repeatedly decocts 1-2 time, and each decocting liquid at 2-3h, and merges by each time controling decocted, and repeatedly decocts to refine wherein effective ingredient.
Preferably, Semen Strychni, Flos Carthami, Fructus Chaenomelis, Radix Glycyrrhizae, Rhizoma Gastrodiae, Rhizoma Belamcandae, Radix Angelicae Pubescentis, Fructus Schisandrae Chinensis, Cortex Cinnamomi, Radix Aconiti Kusnezoffii, Herba Lycopodii, Herba speranskiae tuberculatae are ground into the powder of order granularity more than 80 orders, preferred 80-100 order, pulverizing grinds to form homogeneous powdery and is conducive to obtained homogeneous product.
Preferably, percolation adopt mass percent concentration be more than 90% ethanol carry out, percolation rate controlled, at 5-8ml/min, also will control percolation speed well during percolation operation, continuous solubilizer is while carry out percolation on one side, to keep the content of the effective ingredient of the medicine in its percolate.After percolate mixes with decocting liquid, the relative density of the concentrated extractum obtained is preferably control between 1.03-1.10 under the condition of 60 DEG C in temperature.
Preferably, will more than 24h be soaked in the oil filter to get filtrate by remaining Hippocampus after percolation operation, filtrate and described extractum will be merged.Although through decoction, percolation operation before Hippocampus, in order to reach the object of fully refining, also Hippocampus will be dipped in gasoline and do last refinement operation, just generally need immersion more than 24h that drug effect can be made to refine completely.Further, in the step that extractum mixes with artificial Moschus, Borneolum Syntheticum, methyl salicylate, Camphora, described filtrate, vaseline, zinc oxide, Colophonium, lanoline is also added.These additives prepare the conventional material of mastic, wherein vaseline, the taste of lanoline own are lighter, be not pungent, and it is good to have water proofing property moistening effect, in order to make the easier skin permeation of this wind dispelling analgesic drug product, use convenient, therefore this medicine is made into paste body shape, if make mastic, so follow-uply also comprise cutting, lid lining and the step of stripping and slicing, thus finished product can be formed sell.Certainly this Chinese medicine composition also can make other forms, as long as the medicine containing specific effective ingredient of the present invention all has the effect of wind dispelling pain relieving.
Finally, in order to reach sterilizing, preventing the infection of miscellaneous bacteria, also comprising the step of radicidation under 50-60 DEG C of condition.
Compared with prior art, beneficial effect of the present invention is:
(1) provide a kind of Chinese medicine composition for pathogenic wind expelling and blood circulation promoting, dispersing cold for relieving pain, not only the property of medicine is gentle, effective for pathogenic wind expelling and blood circulation promoting, dispersing cold for relieving pain, and can not recur after recovery from illness, and what after patient takes, sb.'s illness took a favorable turn is fast, and clinical effectiveness is good;
(2) Chinese medicine composition of the present invention possesses the function of pathogenic wind expelling and blood circulation promoting, dispersing cold for relieving pain, and product of the present invention is natural Chinese herbal medicine of drawing materials in addition, has no side effect, the ammonia nitrogen discharge etc. to environment can be reduced after using, reduce environmental pollution, to the mankind and environmentally friendly, environmental protection;
(3) preparation method of the present invention well remains the effective ingredient of each component in raw material, and by the great many of experiments of inventor by concrete processing step mode standard, and simple to operate, flexible, obtained medicament instructions of taking is simple, patient is facilitated to carry, not by environmental constraints.
Detailed description of the invention
Below in conjunction with embodiment, embodiment of the present invention are described in detail, but it will be understood to those of skill in the art that the following example only for illustration of the present invention, and should not be considered as limiting the scope of the invention.Unreceipted actual conditions person in embodiment, the condition of conveniently conditioned disjunction manufacturer suggestion is carried out.Agents useful for same or the unreceipted production firm person of instrument, be and can buy by commercially available the conventional products obtained.
Embodiment 1
Preparation method for the Chinese medicine composition of pathogenic wind expelling and blood circulation promoting, dispersing cold for relieving pain is as follows:
1) each raw material is taken by following quality: Semen Strychni 100g, Flos Carthami 10g, Fructus Chaenomelis 10g, Radix Glycyrrhizae 10g, Rhizoma Gastrodiae 10g, Hippocampus 2g, Borneolum Syntheticum 2g, Rhizoma Belamcandae 1g, Radix Angelicae Pubescentis 2g, Fructus Schisandrae Chinensis 1g, Cortex Cinnamomi 5g, Camphora 10g, artificial Moschus 0.5g, Radix Aconiti Kusnezoffii 1g, Herba Lycopodii 2g, Herba speranskiae tuberculatae 2g, methyl salicylate 10g;
2) Hippocampus bracelet is given cataclasm, load cloth bag, decoct with water secondary, each 2h, collecting decoction, filter;
3) separately get Semen Strychni, Flos Carthami, Fructus Chaenomelis, Radix Glycyrrhizae, Rhizoma Gastrodiae, Rhizoma Belamcandae, Radix Angelicae Pubescentis, Fructus Schisandrae Chinensis, Cortex Cinnamomi, Radix Aconiti Kusnezoffii, Herba Lycopodii, Herba speranskiae tuberculatae be ground into coarse powder, be the ethanol percolation of 90% with the Hippocampus mass percent concentration of above-mentioned loading cloth bag, colourless to percolate, percolate is concentrated, merges with above-mentioned decocting liquid that to make density be that the extractum of 1.03-1.10 (60 DEG C) is for subsequent use;
4) put in appropriate gasoline soak 24h by loading the Hippocampus of cloth bag, filter, discard medicinal residues, gasoline is for subsequent use;
5) rubber, gasoline (gasoline of leaching Hippocampus), lanoline, vaseline, zinc oxide, Colophonium, extractum, artificial Moschus, Borneolum Syntheticum, methyl salicylate, the obtained finished product of Camphora mixing is got.
Embodiment 2
Preparation method for the Chinese medicine composition of pathogenic wind expelling and blood circulation promoting, dispersing cold for relieving pain is as follows:
1) each raw material is taken by following quality: Semen Strychni 400g, Flos Carthami 40g, Fructus Chaenomelis 40g, Radix Glycyrrhizae 40g, Rhizoma Gastrodiae 40g, Hippocampus 8g, Borneolum Syntheticum 10g, Rhizoma Belamcandae 8g, Radix Angelicae Pubescentis 8g, Fructus Schisandrae Chinensis 15g, Cortex Cinnamomi 20g, Camphora 40g, artificial Moschus 5g, Radix Aconiti Kusnezoffii 10g, Herba Lycopodii 20g, Herba speranskiae tuberculatae 20g, methyl salicylate 40g;
2) Hippocampus bracelet is given cataclasm, load cloth bag, decoct with water 3h, filter;
3) separately get Semen Strychni, powder that Flos Carthami, Fructus Chaenomelis, Radix Glycyrrhizae, Rhizoma Gastrodiae, Rhizoma Belamcandae, Radix Angelicae Pubescentis, Fructus Schisandrae Chinensis, Cortex Cinnamomi, Radix Aconiti Kusnezoffii, Herba Lycopodii, Herba speranskiae tuberculatae are ground into more than 80 orders, be the ethanol percolation of 90% with the Hippocampus mass percent concentration of above-mentioned loading cloth bag, percolation rate controlled is at 5-8ml/min, colourless to percolate, percolate is concentrated, merges with above-mentioned decocting liquid that to make density be that the extractum of 1.03-1.10 (60 DEG C) is for subsequent use;
4) put in appropriate gasoline soak 30h by loading the Hippocampus of cloth bag, filter, discard medicinal residues, gasoline is for subsequent use;
5) rubber, gasoline (gasoline of leaching Hippocampus), lanoline, vaseline, zinc oxide, Colophonium, extractum, artificial Moschus, Borneolum Syntheticum, methyl salicylate, the obtained coating of Camphora mixing is got, carry out painting cream, cutting, lid lining, stripping and slicing gets product, radicidation under last 50-60 DEG C condition.
Embodiment 3
Preparation method for the Chinese medicine composition of pathogenic wind expelling and blood circulation promoting, dispersing cold for relieving pain is as follows:
1) each raw material is taken by following quality: Semen Strychni 150g, Flos Carthami 20g, Fructus Chaenomelis 20g, Radix Glycyrrhizae 20g, Rhizoma Gastrodiae 20g, hippocampus 3 g, Borneolum Syntheticum 3g, Rhizoma Belamcandae 2g, Radix Angelicae Pubescentis 3g, Fructus Schisandrae Chinensis 3g, Cortex Cinnamomi 8g, Camphora 20g, artificial Moschus 2g, Radix Aconiti Kusnezoffii 2g, Herba Lycopodii 4g, Herba speranskiae tuberculatae 4g, methyl salicylate 20g;
2) Hippocampus bracelet is given cataclasm, load cloth bag, decoct with water secondary, each 2h, collecting decoction, filter;
3) separately get Semen Strychni, Flos Carthami, Fructus Chaenomelis, Radix Glycyrrhizae, Rhizoma Gastrodiae, Rhizoma Belamcandae, Radix Angelicae Pubescentis, Fructus Schisandrae Chinensis, Cortex Cinnamomi, Radix Aconiti Kusnezoffii, Herba Lycopodii, Herba speranskiae tuberculatae are ground into powder between 80-100 order, be the ethanol percolation of 95% with the Hippocampus mass percent concentration of above-mentioned loading cloth bag, percolation rate controlled is at 6ml/min, colourless to percolate, percolate is concentrated, merges with above-mentioned decocting liquid that to make density be that the extractum of 1.03-1.10 (60 DEG C) is for subsequent use;
4) put in appropriate gasoline soak 30h by loading the Hippocampus of cloth bag, filter, discard medicinal residues, gasoline is for subsequent use;
5) rubber, gasoline (gasoline of leaching Hippocampus), lanoline, vaseline, zinc oxide, Colophonium, extractum, artificial Moschus, Borneolum Syntheticum, methyl salicylate, the obtained coating of Camphora mixing is got, carry out painting cream, cutting, lid lining, stripping and slicing gets product, radicidation under last 50-60 DEG C condition.
Embodiment 4
Preparation method for the Chinese medicine composition of pathogenic wind expelling and blood circulation promoting, dispersing cold for relieving pain is as follows:
1) each raw material is taken by following quality: Semen Strychni 250g, Flos Carthami 30g, Fructus Chaenomelis 30g, Radix Glycyrrhizae 30g, Rhizoma Gastrodiae 30g, Hippocampus 6g, Borneolum Syntheticum 8g, Rhizoma Belamcandae 6g, Radix Angelicae Pubescentis 6g, Fructus Schisandrae Chinensis 10g, Cortex Cinnamomi 15g, Camphora 30g, artificial Moschus 4g, Radix Aconiti Kusnezoffii 8g, Herba Lycopodii 15g, Herba speranskiae tuberculatae 15g, methyl salicylate 30g;
2) Hippocampus bracelet is given cataclasm, load cloth bag, decoct with water secondary, each 2h, collecting decoction, filter;
3) separately get Semen Strychni, Flos Carthami, Fructus Chaenomelis, Radix Glycyrrhizae, Rhizoma Gastrodiae, Rhizoma Belamcandae, Radix Angelicae Pubescentis, Fructus Schisandrae Chinensis, Cortex Cinnamomi, Radix Aconiti Kusnezoffii, Herba Lycopodii, Herba speranskiae tuberculatae are ground into powder between 80-100 order, be the ethanol percolation of 95% with the Hippocampus mass percent concentration of above-mentioned loading cloth bag, percolation rate controlled is at 7ml/min, colourless to percolate, percolate is concentrated, merges with above-mentioned decocting liquid that to make density be that the extractum of 1.03-1.10 (60 DEG C) is for subsequent use;
4) put in appropriate gasoline soak 35h by loading the Hippocampus of cloth bag, filter, discard medicinal residues, gasoline is for subsequent use;
5) rubber, gasoline (gasoline of leaching Hippocampus), lanoline, vaseline, zinc oxide, Colophonium, extractum, artificial Moschus, Borneolum Syntheticum, methyl salicylate, the obtained coating of Camphora mixing is got, carry out painting cream, cutting, lid lining, stripping and slicing gets product, radicidation under last 50-60 DEG C condition.
Embodiment 5
Preparation method for the Chinese medicine composition of pathogenic wind expelling and blood circulation promoting, dispersing cold for relieving pain is as follows:
1) each raw material is taken by following quality: Semen Strychni 200g, Flos Carthami 25g, Fructus Chaenomelis 25g, Radix Glycyrrhizae 25g, Rhizoma Gastrodiae 25g, Hippocampus 5g, Borneolum Syntheticum 6g, Rhizoma Belamcandae 4g, Radix Angelicae Pubescentis 5g, Fructus Schisandrae Chinensis 6g, Cortex Cinnamomi 12g, Camphora 25g, artificial Moschus 3g, Radix Aconiti Kusnezoffii 5g, Herba Lycopodii 10g, Herba speranskiae tuberculatae 10g, methyl salicylate 25g;
2) Hippocampus bracelet is given cataclasm, load cloth bag, decoct with water secondary, each 3h, collecting decoction, filter;
3) separately get Semen Strychni, powder that Flos Carthami, Fructus Chaenomelis, Radix Glycyrrhizae, Rhizoma Gastrodiae, Rhizoma Belamcandae, Radix Angelicae Pubescentis, Fructus Schisandrae Chinensis, Cortex Cinnamomi, Radix Aconiti Kusnezoffii, Herba Lycopodii, Herba speranskiae tuberculatae are ground into more than 90 orders, be the ethanol percolation of 95% with the Hippocampus mass percent concentration of above-mentioned loading cloth bag, percolation rate controlled is at 6ml/min, colourless to percolate, percolate is concentrated, merges with above-mentioned decocting liquid that to make density be that the extractum of 1.03-1.10 (60 DEG C) is for subsequent use;
4) put in appropriate gasoline soak 30h by loading the Hippocampus of cloth bag, filter, discard medicinal residues, gasoline is for subsequent use;
5) rubber, gasoline (gasoline of leaching Hippocampus), lanoline, vaseline, zinc oxide, Colophonium, extractum, artificial Moschus, Borneolum Syntheticum, methyl salicylate, the obtained coating of Camphora mixing is got, carry out painting cream, cutting, lid lining, stripping and slicing gets product, radicidation under last 50-60 DEG C condition.
Experimental example 1
Randomly draw and suffer from lumbar muscle strain, the patient of lumbago and skelalgia 250, age is in 40-85 year, men and women does not limit, be divided into 5 groups, often organize 50, the people of first group uses the Chinese medicine composition of embodiment 1, the people of second group uses the Chinese medicine composition of embodiment 2, the people of the 3rd group uses the Chinese medicine composition of embodiment 3, the people of the 4th group uses the Chinese medicine composition of embodiment 4, the people of the 5th group uses commercially available Moschus plaster (comparative example 1), adhere to one month, other treatment hands section need not be coordinated during this, after one month, the people participating in statistical experiment is investigated, survey result is as following table 1:
Table 1 survey result
Concrete evaluation criterion is as follows:
Cure: joint is painless, can carry out normal physical work;
Be very effective: when dry weight is lived once in a while, wind-engaging place also can feels pain, but the state of an illness is clearly better;
Without positive effect: do not feel there is any improvement.
As can be seen from upper table 1, after employing the Chinese medicine composition for pathogenic wind expelling and blood circulation promoting, dispersing cold for relieving pain of the embodiment of the present invention, the curative effect of patient is remarkable, wherein do not cure with there is no positive effect that person's state of an illness is slightly heavy, need just can take effect the course for the treatment of of longer time, the Chinese medicine composition of the embodiment of the present invention can feel that the state of an illness take a favorable turn phenomenon in general 1 month, the 3-6 month can cure completely, have no side effect compared to Western medicine, but also serve effect of health care, the every function of human body can be improved, improve body immunity.
Although illustrate and describe the present invention with specific embodiment, however it will be appreciated that can to make when not deviating from the spirit and scope of the present invention many other change and amendment.Therefore, this means to comprise all such changes and modifications belonged in the scope of the invention in the following claims.

Claims (10)

1. the Chinese medicine composition for pathogenic wind expelling and blood circulation promoting, dispersing cold for relieving pain, it is characterized in that, it is made primarily of following raw material: in mass fraction, Semen Strychni 100-400 part, Flos Carthami 10-40 part, Fructus Chaenomelis 10-40 part, Radix Glycyrrhizae 10-40 part, Rhizoma Gastrodiae 10-40 part, Hippocampus 2-8 part, Borneolum Syntheticum 2-10 part, Rhizoma Belamcandae 1-8 part, Radix Angelicae Pubescentis 2-8 part, Fructus Schisandrae Chinensis 1-15 part, Cortex Cinnamomi 5-20 part, Camphora 10-40 part, artificial Moschus 0.5-5 part, Radix Aconiti Kusnezoffii 1-10 part, Herba Lycopodii 2-20 part, Herba speranskiae tuberculatae 2-20 part, methyl salicylate 10-40 part.
2. the Chinese medicine composition for pathogenic wind expelling and blood circulation promoting, dispersing cold for relieving pain according to claim 1, it is characterized in that, described raw material comprises: in mass fraction, Semen Strychni 150-250 part, Flos Carthami 20-30 part, Fructus Chaenomelis 20-30 part, Radix Glycyrrhizae 20-30 part, Rhizoma Gastrodiae 20-30 part, hippocampus 3-6 parts, Borneolum Syntheticum 3-8 part, Rhizoma Belamcandae 2-6 part, Radix Angelicae Pubescentis 3-6 part, Fructus Schisandrae Chinensis 3-10 part, Cortex Cinnamomi 8-15 part, Camphora 20-30 part, artificial Moschus 2-4 part, Radix Aconiti Kusnezoffii 2-8 part, Herba Lycopodii 4-15 part, Herba speranskiae tuberculatae 4-15 part, methyl salicylate 20-30 part.
3. the Chinese medicine composition for pathogenic wind expelling and blood circulation promoting, dispersing cold for relieving pain according to claim 1 and 2, is characterized in that, described raw material comprises: in mass fraction, Semen Strychni 200 parts, 25 parts, Flos Carthami, Fructus Chaenomelis 25 parts, 25 parts, Radix Glycyrrhizae, 25 parts, Rhizoma Gastrodiae, Hippocampus 5 parts, Borneolum Syntheticum 6 parts, Rhizoma Belamcandae 4 parts, Radix Angelicae Pubescentis 5 parts, Fructus Schisandrae Chinensis 6 parts, Cortex Cinnamomi 12 parts, Camphora 25 parts, artificial Moschus 3 parts, Radix Aconiti Kusnezoffii 5 parts, Herba Lycopodii 10 parts, Herba speranskiae tuberculatae 10 parts, methyl salicylate 25 parts.
4. the preparation method of the Chinese medicine composition for pathogenic wind expelling and blood circulation promoting, dispersing cold for relieving pain described in any one of claim 1-3, is characterized in that, comprise the steps:
Hippocampus is pulverized and decocts to obtain decocting liquid, for subsequent use;
After Semen Strychni, Flos Carthami, Fructus Chaenomelis, Radix Glycyrrhizae, Rhizoma Gastrodiae, Rhizoma Belamcandae, Radix Angelicae Pubescentis, Fructus Schisandrae Chinensis, Cortex Cinnamomi, Radix Aconiti Kusnezoffii, Herba Lycopodii, Herba speranskiae tuberculatae are pulverized and mixed with the remaining Hippocampus of decoction, percolation obtains percolate, concentrated;
Percolate after concentrated and described decocting liquid are merged and are condensed into extractum, and mix with artificial Moschus, Borneolum Syntheticum, methyl salicylate, Camphora.
5. the preparation method of the Chinese medicine composition for pathogenic wind expelling and blood circulation promoting, dispersing cold for relieving pain according to claim 4, is characterized in that, it is 1-2 time that Hippocampus pulverizes the number of times decocted, and each decocting liquid at 2-3h, and merges by each time controling decocted.
6. the preparation method of the Chinese medicine composition for pathogenic wind expelling and blood circulation promoting, dispersing cold for relieving pain according to claim 4, it is characterized in that, Semen Strychni, Flos Carthami, Fructus Chaenomelis, Radix Glycyrrhizae, Rhizoma Gastrodiae, Rhizoma Belamcandae, Radix Angelicae Pubescentis, Fructus Schisandrae Chinensis, Cortex Cinnamomi, Radix Aconiti Kusnezoffii, Herba Lycopodii, Herba speranskiae tuberculatae are ground into the powder of order granularity more than 80 orders, preferred 80-100 order.
7. the preparation method of the Chinese medicine composition for pathogenic wind expelling and blood circulation promoting, dispersing cold for relieving pain according to claim 4, is characterized in that, percolation adopt mass percent concentration be more than 90% ethanol carry out, percolation rate controlled is at 5-8ml/min.
8. the preparation method of the Chinese medicine composition for pathogenic wind expelling and blood circulation promoting, dispersing cold for relieving pain according to claim 4, is characterized in that, the relative density of extractum is control between 1.03-1.10 under the condition of 60 DEG C in temperature.
9. the preparation method of the Chinese medicine composition for pathogenic wind expelling and blood circulation promoting, dispersing cold for relieving pain according to claim 4, is characterized in that, will soak more than 24h in the oil and filters to get filtrate by remaining Hippocampus after percolation operation, and filtrate and described extractum be merged.
10. the preparation method of the Chinese medicine composition for pathogenic wind expelling and blood circulation promoting, dispersing cold for relieving pain according to claim 9, it is characterized in that, in the step that extractum mixes with artificial Moschus, Borneolum Syntheticum, methyl salicylate, Camphora, described filtrate, also add vaseline, zinc oxide, Colophonium, lanoline.
CN201510954391.5A 2015-12-17 2015-12-17 Traditional Chinese medicine composition for dispelling wind, activating blood, dissipating cold, and relieving pain and preparation method thereof Pending CN105434900A (en)

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