CN105431738B - 胃癌的预后预测模型的建立方法 - Google Patents
胃癌的预后预测模型的建立方法 Download PDFInfo
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- CN105431738B CN105431738B CN201480024783.5A CN201480024783A CN105431738B CN 105431738 B CN105431738 B CN 105431738B CN 201480024783 A CN201480024783 A CN 201480024783A CN 105431738 B CN105431738 B CN 105431738B
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- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
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- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
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- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/5753—Immunoassay; Biospecific binding assay; Materials therefor for cancer of the stomach or small intestine
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
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- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
- G16B20/20—Allele or variant detection, e.g. single nucleotide polymorphism [SNP] detection
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- G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
- G16B40/30—Unsupervised data analysis
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- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/156—Polymorphic or mutational markers
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Biomedical Technology (AREA)
- Pathology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- General Engineering & Computer Science (AREA)
- Evolutionary Biology (AREA)
- Bioinformatics & Computational Biology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Theoretical Computer Science (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Data Mining & Analysis (AREA)
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- Hospice & Palliative Care (AREA)
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR1020130037336A KR101501826B1 (ko) | 2013-04-05 | 2013-04-05 | 위암에 대한 예후 예측 모형의 제조방법 |
| KR10-2013-0037336 | 2013-04-05 | ||
| PCT/KR2014/002959 WO2014163445A1 (ko) | 2013-04-05 | 2014-04-07 | 위암에 대한 예후 예측 모형의 제조방법 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN105431738A CN105431738A (zh) | 2016-03-23 |
| CN105431738B true CN105431738B (zh) | 2017-11-03 |
Family
ID=51658661
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201480024783.5A Expired - Fee Related CN105431738B (zh) | 2013-04-05 | 2014-04-07 | 胃癌的预后预测模型的建立方法 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20160040253A1 (https=) |
| EP (1) | EP2982986B1 (https=) |
| JP (1) | JP6356217B2 (https=) |
| KR (1) | KR101501826B1 (https=) |
| CN (1) | CN105431738B (https=) |
| WO (1) | WO2014163445A1 (https=) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2018094569A1 (zh) * | 2016-11-22 | 2018-05-31 | 深圳华大基因研究院 | 多肽及其应用 |
| WO2018098636A1 (zh) * | 2016-11-29 | 2018-06-07 | 深圳华大基因研究院 | 多肽及其应用 |
| KR102127449B1 (ko) * | 2017-02-08 | 2020-06-26 | 사회복지법인 삼성생명공익재단 | 생존율 예측 모델 생성 방법, 장치 및 컴퓨터 프로그램 |
| CN108504732A (zh) * | 2017-02-27 | 2018-09-07 | 复旦大学附属华山医院 | 一种建立胃癌的风险预测模型的方法 |
| KR101940657B1 (ko) * | 2017-04-24 | 2019-01-21 | (주) 노보믹스 | 위암의 생물학적 특성에 기반한 군 구분 및 예후 예측 시스템 |
| CN107090503B (zh) * | 2017-04-27 | 2020-06-19 | 元码基因科技(北京)股份有限公司 | 探针组合物、基因捕获芯片、试剂盒及其应用 |
| CN107641653B (zh) * | 2017-10-20 | 2021-02-19 | 南方医科大学南方医院 | Macc1-as1探针在制备用于预测胃癌临床预后的诊断试剂中的应用 |
| CN113851185B (zh) * | 2021-11-29 | 2022-04-19 | 求臻医学科技(北京)有限公司 | 一种用于非小细胞肺癌患者免疫治疗的预后评估方法 |
| CN115820853A (zh) * | 2022-09-22 | 2023-03-21 | 中国医科大学附属第一医院 | 一种malat1基因snp位点及其作为胃癌预后标志物的应用 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012081898A2 (ko) * | 2010-12-13 | 2012-06-21 | 사회복지법인 삼성생명공익재단 | 위암의 예후 예측용 마커 및 이를 이용하는 위암의 예후 예측 방법 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007530017A (ja) * | 2004-03-02 | 2007-11-01 | ザ ジョンズ ホプキンス ユニバーシティ | ヒトの癌におけるpik3ca遺伝子の変異 |
| ES2553442T3 (es) * | 2006-01-05 | 2015-12-09 | The Ohio State University Research Foundation | Procedimientos basados en los microARN para el diagnóstico, pronóstico y tratamiento del cáncer de pulmón |
| CA2648021A1 (en) * | 2006-03-31 | 2007-10-11 | Ordway Research Institute, Inc. | Prognostic and diagnostic method for cancer therapy |
| US8680041B2 (en) * | 2006-10-26 | 2014-03-25 | Genentech, Inc. | Genetic variations associated with tumors |
| EP2288728A4 (en) * | 2008-05-15 | 2011-11-02 | Univ Southern California | GENOTYP AND EXPRESSION ANALYSIS FOR USE IN PROGNOSIS AND THERAPY SELECTION |
| KR20120061010A (ko) * | 2010-11-02 | 2012-06-12 | 서울대학교산학협력단 | 위암 진단 방법 |
| CN103906848B (zh) * | 2011-08-18 | 2016-03-02 | 雀巢产品技术援助有限公司 | 用于检测等位变体的组合物和方法 |
-
2013
- 2013-04-05 KR KR1020130037336A patent/KR101501826B1/ko not_active Expired - Fee Related
-
2014
- 2014-04-07 US US14/782,519 patent/US20160040253A1/en not_active Abandoned
- 2014-04-07 EP EP14779750.0A patent/EP2982986B1/en not_active Not-in-force
- 2014-04-07 WO PCT/KR2014/002959 patent/WO2014163445A1/ko not_active Ceased
- 2014-04-07 CN CN201480024783.5A patent/CN105431738B/zh not_active Expired - Fee Related
- 2014-04-07 JP JP2016506253A patent/JP6356217B2/ja not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012081898A2 (ko) * | 2010-12-13 | 2012-06-21 | 사회복지법인 삼성생명공익재단 | 위암의 예후 예측용 마커 및 이를 이용하는 위암의 예후 예측 방법 |
Non-Patent Citations (4)
| Title |
|---|
| Deep sequencing of gastric carcinoma reveals somatic mutations relevant to personalized medicine;Joanna D Holbrook et al;《Journal of Translational Medicine》;20110725;第9卷;第1-13页 * |
| Prognostic significance of genetic alterations detected by high-density single nucleotide polymorphism array in gastric cancer;Motohisa Tada et al;《cancer science》;20100312;第1261-1269页 * |
| Relevance of MET activation and genetic alterations of KRAS andE-cadherinforcetuximabsensitivity of gastric cancer cell lines;Stefan Heindl;《J Cancer Res Clin Oncol》;20120131;第138卷;第843-858页 * |
| The overexpression of c-met as a prognostic indicator for gastric carcinoma compared to p53 and p21 nuclear accumulation;UTA DREBBER et al;《ONCOLOGY REPORTS 》;20080601;第19卷;第1477-1483页 * |
Also Published As
| Publication number | Publication date |
|---|---|
| KR20140121524A (ko) | 2014-10-16 |
| KR101501826B1 (ko) | 2015-03-13 |
| WO2014163445A1 (ko) | 2014-10-09 |
| EP2982986A1 (en) | 2016-02-10 |
| JP2016515390A (ja) | 2016-05-30 |
| CN105431738A (zh) | 2016-03-23 |
| EP2982986B1 (en) | 2019-01-30 |
| US20160040253A1 (en) | 2016-02-11 |
| EP2982986A4 (en) | 2016-12-07 |
| JP6356217B2 (ja) | 2018-07-11 |
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Effective date of registration: 20170626 Address after: Seoul, South Kerean Applicant after: Novamax Co.,Ltd. Address before: Seoul, South Kerean Applicant before: INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI University |
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Address after: Seoul, South Kerean Patentee after: NOVOMICS Co.,Ltd. Address before: Seoul, South Kerean Patentee before: Novamax Co.,Ltd. |
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Granted publication date: 20171103 |