CN105431175B - 透皮递送系统 - Google Patents

透皮递送系统 Download PDF

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Publication number
CN105431175B
CN105431175B CN201480029019.7A CN201480029019A CN105431175B CN 105431175 B CN105431175 B CN 105431175B CN 201480029019 A CN201480029019 A CN 201480029019A CN 105431175 B CN105431175 B CN 105431175B
Authority
CN
China
Prior art keywords
nitrite
hydrogel
layer
pharmaceutically active
disease
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201480029019.7A
Other languages
English (en)
Chinese (zh)
Other versions
CN105431175A (zh
Inventor
C·B·伍德
H·S·芒罗
N·D·布特
J·E·斯图尔特
A·T·塔克
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Edixomed Ltd
Queen Mary University of London
First Water Ltd
Original Assignee
Edixomed Ltd
Queen Mary University of London
First Water Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Edixomed Ltd, Queen Mary University of London, First Water Ltd filed Critical Edixomed Ltd
Publication of CN105431175A publication Critical patent/CN105431175A/zh
Application granted granted Critical
Publication of CN105431175B publication Critical patent/CN105431175B/zh
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0004—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing inorganic materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7007—Drug-containing films, membranes or sheets
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/44—Medicaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0009—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials
    • A61L26/0014—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form containing macromolecular materials obtained by reactions only involving carbon-to-carbon unsaturated bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061—Use of materials characterised by their function or physical properties
    • A61L26/0066—Medicaments; Biocides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061—Use of materials characterised by their function or physical properties
    • A61L26/008—Hydrogels or hydrocolloids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
    • A61L26/0061—Use of materials characterised by their function or physical properties
    • A61L26/009—Materials resorbable by the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
    • A61L2300/114—Nitric oxide, i.e. NO
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/402—Anaestetics, analgesics, e.g. lidocaine

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Materials Engineering (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Inorganic Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Plant Substances (AREA)
CN201480029019.7A 2013-05-20 2014-05-20 透皮递送系统 Active CN105431175B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB201309092A GB201309092D0 (en) 2013-05-20 2013-05-20 Transdermal delivery system
GB1309092.3 2013-05-20
PCT/GB2014/051544 WO2014188175A1 (en) 2013-05-20 2014-05-20 Transdermal delivery system

Publications (2)

Publication Number Publication Date
CN105431175A CN105431175A (zh) 2016-03-23
CN105431175B true CN105431175B (zh) 2018-12-28

Family

ID=48747065

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201480029019.7A Active CN105431175B (zh) 2013-05-20 2014-05-20 透皮递送系统

Country Status (18)

Country Link
US (1) US10010648B2 (enExample)
EP (1) EP2908873B1 (enExample)
JP (1) JP6446035B2 (enExample)
CN (1) CN105431175B (enExample)
AU (1) AU2014270116B2 (enExample)
DK (1) DK2908873T3 (enExample)
ES (1) ES2658037T3 (enExample)
GB (1) GB201309092D0 (enExample)
HR (1) HRP20180079T1 (enExample)
HU (1) HUE035847T2 (enExample)
LT (1) LT2908873T (enExample)
NO (1) NO2908873T3 (enExample)
PL (1) PL2908873T3 (enExample)
PT (1) PT2908873T (enExample)
RS (1) RS56833B1 (enExample)
SI (1) SI2908873T1 (enExample)
SM (1) SMT201800030T1 (enExample)
WO (1) WO2014188175A1 (enExample)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB201420761D0 (en) 2014-11-21 2015-01-07 Edixomed Ltd And First Water Ltd Dressing system
GB201520990D0 (en) 2015-11-27 2016-01-13 Edixomed Ltd Dressing system
TWI605843B (zh) * 2016-12-21 2017-11-21 嘉藥學校財團法人嘉南藥理大學 氣相經皮吸收系統
WO2019166572A1 (en) 2018-02-28 2019-09-06 Pharming Intellectual Property B.V. Pharmaceutical system for transdermal administration of a c1 -esterase inhibitor
US12220493B2 (en) 2018-07-16 2025-02-11 Systagenix Wound Management, Limited Nitric oxide producing collagen/ORC dressing
EP3908241A4 (en) * 2019-01-11 2022-12-07 Noxsano Inc. COMPOSITION FOR GENERATION OF ELECTROCHEMICAL GASOTRANSMITTER AND BIMETALLIC CELLS FOR GENERATION OF GASOTRANSMITTER
EP3980032A1 (en) * 2019-06-04 2022-04-13 Thirty Respiratory Limited Methods and compositions for generating nitric oxide and uses thereof to deliver nitric oxide via the respiratory tract
GB2599576B (en) 2019-06-04 2023-09-13 Thirty Holdings Ltd Methods and compositions for generating nitric oxide and uses thereof
CA3172240A1 (en) * 2020-04-02 2021-10-07 Maria ASPIOTI Wound dressing
GB202004868D0 (en) * 2020-04-02 2020-05-20 Smith & Nephew Wound care compositions and methods of preparation thereof
GB2610721B (en) 2020-04-23 2024-07-31 Thirty Respiratory Ltd Compositions for treating and combatting tuberculosis
EP4138795A1 (en) 2020-04-23 2023-03-01 Thirty Respiratory Limited Nitric oxide or nitric oxide releasing compositions for use in treating sars-cov and sars-cov-2
CN113101053A (zh) * 2021-03-30 2021-07-13 上海健康医学院 一种可释放一氧化氮的创伤敷料
US12514756B1 (en) 2024-10-08 2026-01-06 Covidien Lp Dermal patch and systems, kits, and methods associated therewith

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002017881A2 (en) * 2000-08-30 2002-03-07 Queen Mary & Westfield College Transdermal pharmaceutical delivery composition
CN101878046A (zh) * 2007-08-09 2010-11-03 香榭有限公司 有关皮肤敷料的改进

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA837139B (en) 1982-10-26 1984-05-30 Kennecott Corp Two high hot rolling mill process and narrow strip product
EP0139127A1 (en) 1983-08-22 1985-05-02 F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft Transdermal drug delivery device and its preparation
EP1100556B1 (en) 1998-07-31 2003-11-12 First Water Limited Bioadhesive compositions and biomedical electrodes containing them
GB9905425D0 (en) 1999-03-09 1999-05-05 Queen Mary & Westfield College Pharmaceutical composition
CA2323382C (en) 2000-10-17 2004-04-13 Pharma Mag Inc. Wound dressing
GB0715556D0 (en) 2007-08-09 2007-09-19 Insense Ltd Improvements relating to skin dressings
US20100055161A1 (en) 2008-08-27 2010-03-04 Dong June Ahn Hydrogel face mask for delivering skin care agents
CA2777066C (en) 2009-10-14 2020-02-18 TheraVasc, LLC Pharmaceutical formulations of nitrite and uses thereof
ES2675879T3 (es) 2009-12-22 2018-07-13 Rigshospitalet, Copenhagen University Hospital Productos para el cuidado de heridas
GB201309091D0 (en) * 2013-05-20 2013-07-03 Edixomed Ltd Dressing system

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002017881A2 (en) * 2000-08-30 2002-03-07 Queen Mary & Westfield College Transdermal pharmaceutical delivery composition
CN101878046A (zh) * 2007-08-09 2010-11-03 香榭有限公司 有关皮肤敷料的改进

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
Biomedical evaluation of a novel nitrogen oxides releasing wound dressing;Rachna N. Dave等;《J Mater Sci:Mater Med》;20120922;第23卷(第12期);3097-3106 *

Also Published As

Publication number Publication date
JP6446035B2 (ja) 2018-12-26
GB201309092D0 (en) 2013-07-03
EP2908873A1 (en) 2015-08-26
RS56833B1 (sr) 2018-04-30
LT2908873T (lt) 2018-02-12
SMT201800030T1 (it) 2018-03-08
NO2908873T3 (enExample) 2018-03-17
AU2014270116A1 (en) 2015-12-10
JP2016518458A (ja) 2016-06-23
SI2908873T1 (en) 2018-04-30
AU2014270116B2 (en) 2017-12-21
PT2908873T (pt) 2018-01-23
WO2014188175A1 (en) 2014-11-27
ES2658037T3 (es) 2018-03-08
HUE035847T2 (en) 2018-05-28
US20160089473A1 (en) 2016-03-31
EP2908873B1 (en) 2017-10-18
CN105431175A (zh) 2016-03-23
DK2908873T3 (en) 2018-01-22
US10010648B2 (en) 2018-07-03
HRP20180079T1 (hr) 2018-04-06
PL2908873T3 (pl) 2018-06-29

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