CN105412769A - Traditional Chinese medicine preparation for treating phlegmatic hygrosis orifice blocking type multiple tic disorder of children - Google Patents
Traditional Chinese medicine preparation for treating phlegmatic hygrosis orifice blocking type multiple tic disorder of children Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicine preparation for treating phlegmatic hygrosis orifice blocking type multiple tic disorder of children and belongs to the technical field of traditional Chinese medicine. According to the traditional Chinese medicine preparation, starting from the theory of diagnosis and treatment based on an overall analysis of the illness and the condition of patients of traditional Chinese medicine, targeted to the pathogenesis of multiple tic disorder of children, multiple types of traditional Chinese medicine including isodon amethystoides, mile swertia, bulbophvl-lum calodictyon schltr., water tatarian aster, beautiful galangal fruits, swertia punicea, gomphrena globosa, bauhinia brachycarpa, gordon euryale seed roots, stellaria yunnanensis, holly leaves are selected to be decocted into decoction, and it is proved by clinic experiment that the total effective rate reaches 92.5%.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation, particularly relate to a kind of Chinese medicine preparation for the treatment of phlegm-damp aperture-blocking type Tourette syndrome.
Background technology
Tourette syndrome is also known as coprolalia syndrome, and mainly comprise transient tic disorder, chronic motor or vocal tic disorder, sounding combine tic disorder with multi-motion, symptom has obvious undulatory property.Prevalence is 0.05%-3%, and in ascendant trend year by year, be more common in 2-15 year child, man is more than female.Think that the cause of disease is main and hereditary at present, central nervous system mediators metabolic imbalance and spirit, psychology, family, Thinking of Social Factors Influence be relevant.The central nervous system agents treatments such as the multiplex haloperidol of doctor trained in Western medicine, but curative effect individual variation is large, and Time of Administration is long, side effect is obvious, after drug withdrawal, symptom easily repeatedly, and lack the Accommodation to infant allomeric function and Psychology and behaviors state, thus make it be difficult to for most of infant and the head of a family accept.Applicant is in clinical practice for many years, and according to theory of Chinese medical science, application Children Treated with Chinese Traditional Drugs multiple pumping symptoms not only achieves good curative effect, and cheap, and side effect is little, for more and more patient and the head of a family accept.
Summary of the invention
The object of this invention is to provide a kind of Chinese medicine preparation for the treatment of phlegm-damp aperture-blocking type Tourette syndrome.Child's multiple pumping symptoms belongs to " endogenous wind " of motherland's medical science, “ clonic convulsion " category: Chinese medicine is stopped over dirty in " liver,spleen,kidney " three at treatment primary disease differentiation of five Zang, this disease of dialectical treatment should with dispelling phlegm and eliminating dampness, spleen invigorating, suppressing the hyperactive liver, nourishing kidney, relieve dizziness, high fever, infantile convulsions, epilepsy, etc. as method.
The object of the invention is to be achieved through the following technical solutions, the Chinese medicine preparation of this treatment phlegm-damp aperture-blocking type Tourette syndrome is made up of the Chinese medicine of following weight portion: fragrant bitter edible plant dish 8-14 part, Swertia mileensis T.N. Ho et W. L. Shi 9-15 part, Herba Bulbophylli Odoratissim 10-20 part, Radix Lactucae elatae 8-14 part, Semen alpinia zerumbet 6-12 part, Herba Swertiae Puniceae 20-30 part, Flos Gomphrenae 40-60 part, Herba Lespedezae Cuneatae 20-30 part, Radix Euryales 20-30 part, Radix Stellariae Yunnanensis 25-35 part, Folium Ilicis Cornutae 10-16 part.
Preferred: Herba Rabdosiae glaucocalycis 11 parts, Swertia mileensis T.N. Ho et W. L. Shi 12 parts, Herba Bulbophylli Odoratissim 15 parts, Radix Lactucae elatae 11 parts, Semen alpinia zerumbet 9 parts, 25 parts, Herba Swertiae Puniceae, Flos Gomphrenae 50 parts, Herba Lespedezae Cuneatae 25 parts, Radix Euryales 25 parts, Radix Stellariae Yunnanensis 30 parts, Folium Ilicis Cornutae 13 parts.
Compound method: traditionally make decoction.
Fang Zhong: Herba Rabdosiae glaucocalycis heat-clearing and toxic substances removing, spleen invigorating are invigorated blood circulation; Swertia mileensis T.N. Ho et W. L. Shi heat-clearing and toxic substances removing, soothing the liver stomach invigorating, anti-inflammation and sterilization; Herba Bulbophylli Odoratissim moistening the lung and resolving phlegm, promoting the circulation of QI to relieve pain; Radix Lactucae elatae relieving cough and resolving phlegm, to dispel the wind; Semen alpinia zerumbet dampness cold relieving, expectorant, spleen invigorating warming the stomach; Herba Swertiae Puniceae liver heat removing function of gallbladder promoting, except damp and clearing heat; Flos Gomphrenae liver heat removing eliminating stagnation, relieving cough and relieving asthma; Herba Lespedezae Cuneatae invigorating the liver and kidney, lung benefiting the moon, dissipating blood stasis for subsidence of swelling; Radix Euryales reinforcing spleen and kidney; Radix Stellariae Yunnanensis spleen invigorating liver-nourishing kidney-boosting; Folium Ilicis Cornutae invigorating the liver and kidney, qi and blood invigorating, wind-damp dispelling.
Clinical data
1, physical data selects in May ,-2013 in March, 2010 my Out-patient Department to see patients infant 80 example, is divided into treatment group 40 example at random, matched group 40 example by medical sequencing.In treatment group 40 example, man 19 example, female 21 example, age reckling 4 years old 6 months, the maximum 15 years old, the mean age is 7.61 years old; The shortest person of the course of disease 14 months, most elder 2 years 9 months, average course of disease is 1 year 8 months.In matched group 40 example, man 20 example, female 20 example; Age reckling 4 years old 2 months, the maximum 16 years old, 8.1 years old mean age; The shortest person of the course of disease 13 months, most elder 2 years 7 months, average course of disease is 1 year 9 months.Through statistical analysis, two groups of infants there was no significant difference in age, sex, the course of disease, has comparability.
2, diagnostic criteria Western medicine diagnose standard reference " child tic disorder diagnostic point " onset is before 18 years old; Show as multi-motion to twitch and the twitch of one or more sounding, the two occurs simultaneously or successively; The course of disease more than 1 year, and in 1 year, remission is no more than 2 months; Get rid of rheumatic chorea, hepatolenticular degeneration, the outbreak of epilepsy myoclonic, psychogenic twitch, drug induccd twitch and other extrapyramidal diseases; Standards of Chinese Medical Syndrome Differentiation is formulated with reference to " Pediatrics of Chinese Medicine ".Primary symptom: motion is twitched, sounding is twitched; Secondary disease: being irritable and getting angry easily, shallow complexion, stomach is received depressed; Picture of the tongue, pulse condition: light red tongue, Tai Bai or greasy, thready and stringy pulse.Possess primary symptom 1 and time disease more than 2 simultaneously, with reference to tongue fur, pulse condition, can be dialectical.
3, inclusive criteria meets above-mentioned Western medicine diagnose and Standards of Chinese Medical Syndrome Differentiation; 4 ~ 12 years old age; Other Chinese and western drugses inactive two weeks time medical; Infants ' parents signature Informed Consent Form.
4, exclusion standard is with internal medicine serious disease persons such as the heart, liver, kidneys.
5, treatment and care method treatment group take Chinese medicine composition of the present invention, take Herba Rabdosiae glaucocalycis 11g, Swertia mileensis T.N. Ho et W. L. Shi 12g, Herba Bulbophylli Odoratissim 15g, Radix Lactucae elatae 11g, Semen alpinia zerumbet 9g, Herba Swertiae Puniceae 25g, Flos Gomphrenae 50g, Herba Lespedezae Cuneatae 25g, Radix Euryales 25g, Radix Stellariae Yunnanensis 30g, Folium Ilicis Cornutae 13g.Every day 1 dose, decoct 2 day, fried liquid 100 ~ 150ml, divide and take for 3 times.Matched group gives Assay for Haloperidol Tablets (Ningbo bright red eagle Pharmaceutical limited company, the accurate word H33020585 of traditional Chinese medicines), oral from low dose of 0.05mg/ (kgd), every day 2 times, take the circumstances into consideration dosage or decrement according to the therapeutic effect of medicine, maximal dose is no more than 4mg/ days.Treat all continuously after 2 months for two groups and add up curative effect.
In therapeutic process, doctor and the head of a family should notice that Psychology of childhood patients quality is cultivated, and must guard against applying pressure, give carefree growth environment.Body-building is taken exercise, and improves self diathesis, attacks in the heresy of minimizing six climate exopathogens.Eat pungent rich product less, stop the damage of delicious food savoury to taste.Must be careful in one's diet after recovery from illness conditioning, and psychology is nursed, and makes it spend the juvenile period of susceptible disease smoothly.
6, criterion of therapeutical effect recovery from illness: disappear completely, without recurrence in 2a through treatment twitch, obscene words; Effective: to twitch through treatment, obscene words disappear, catch a cold or excited time recurrence, and the more original action of action alleviates one-level; Effective: to twitch through treatment, obscene words alleviate one-level, catch a cold or excited time repeatedly, action is as front or increase the weight of one-level; Invalid: the state of an illness is improved not obvious.
7, therapeutic outcome patient treatment observe the curative effect after 2 months, treatment group 40 example, 14 examples of wherein fully recovering (35%), effective 14 examples (35%), 9 examples that take a turn for the better (22.5%), invalid 3 examples (7.5%), total effective rate 92.5%.Matched group 40 example, 6 examples of wherein fully recovering (15%), effective 9 examples (22.5%), 12 examples that take a turn for the better (30%), invalid 13 examples (32.5%), total effective rate 67.5%.Two groups of total effective rate comparing differences have significant (P < 0.05), and treatment group therapeutic effect is obviously better than matched group.Carry out the conventional and Liver and kidney function of blood, urine, feces for primary disease, the relevant physico-chemical examination such as electrocardiogram, carries out treatment cross-reference, and treatment group is without any ANOMALOUS VARIATIONS, and nothing such as to affect the treatment at the untoward reaction, and clinical treatment achieves good curative effect.Matched group has 5 examples to occur drowsiness symptom, and the symptoms such as dyspepsia, nauseating, dizziness is weak appear in 3 examples, transference cure after drug withdrawal.
Detailed description of the invention
Embodiment one: take Herba Rabdosiae glaucocalycis 8g, Swertia mileensis T.N. Ho et W. L. Shi 9g, Herba Bulbophylli Odoratissim 10g, Radix Lactucae elatae 8g, Semen alpinia zerumbet 6g, Herba Swertiae Puniceae 20g, Flos Gomphrenae 40g, Herba Lespedezae Cuneatae 20g, Radix Euryales 20g, Radix Stellariae Yunnanensis 25g, Folium Ilicis Cornutae 10g, traditionally make decoction.
Embodiment two: take fragrant bitter edible plant dish 11g, Swertia mileensis T.N. Ho et W. L. Shi 12g, Herba Bulbophylli Odoratissim 15g, Radix Lactucae elatae 11g, Semen alpinia zerumbet 9g, Herba Swertiae Puniceae 25g, Flos Gomphrenae 50g, Herba Lespedezae Cuneatae 25g, Radix Euryales 25g, Radix Stellariae Yunnanensis 30g, Folium Ilicis Cornutae 13g, traditionally make decoction.
Embodiment three: take Herba Rabdosiae glaucocalycis 14g, Swertia mileensis T.N. Ho et W. L. Shi 15g, Herba Bulbophylli Odoratissim 20g, Radix Lactucae elatae 14g, Semen alpinia zerumbet 12g, Herba Swertiae Puniceae 30g, Flos Gomphrenae 60g, Herba Lespedezae Cuneatae 30g, Radix Euryales 30g, Radix Stellariae Yunnanensis 35g, Folium Ilicis Cornutae 16g, traditionally make decoction.
Claims (2)
1. treat a Chinese medicine preparation for phlegm-damp aperture-blocking type Tourette syndrome, it is characterized in that this Chinese medicine preparation is made up of the Chinese medicine of following weight portion: Herba Rabdosiae glaucocalycis 8-14 part, Swertia mileensis T.N. Ho et W. L. Shi 9-15 part, Herba Bulbophylli Odoratissim 10-20 part, Radix Lactucae elatae 8-14 part, Semen alpinia zerumbet 6-12 part, Herba Swertiae Puniceae 20-30 part, Flos Gomphrenae 40-60 part, Herba Lespedezae Cuneatae 20-30 part, Radix Euryales 20-30 part, Radix Stellariae Yunnanensis 25-35 part, Folium Ilicis Cornutae 10-16 part.
2. a kind of Chinese medicine preparation for the treatment of phlegm-damp aperture-blocking type Tourette syndrome as claimed in claim 1, is characterized in that this Chinese medicine preparation is made up of the Chinese medicine of following weight portion: preferred: Herba Rabdosiae glaucocalycis 11 parts, Swertia mileensis T.N. Ho et W. L. Shi 12 parts, Herba Bulbophylli Odoratissim 15 parts, Radix Lactucae elatae 11 parts, Semen alpinia zerumbet 9 parts, 25 parts, Herba Swertiae Puniceae, Flos Gomphrenae 50 parts, Herba Lespedezae Cuneatae 25 parts, Radix Euryales 25 parts, Radix Stellariae Yunnanensis 30 parts, Folium Ilicis Cornutae 13 parts.
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104056078A (en) * | 2014-07-01 | 2014-09-24 | 徐丽丽 | Traditional Chinese medicine preparation for treating tourette syndrome and nursing method |
| CN104055906A (en) * | 2014-07-01 | 2014-09-24 | 马富玲 | Traditional Chinese medicine preparation for treating heart and spleen heat type tourette syndrome |
| CN104096081A (en) * | 2014-07-01 | 2014-10-15 | 王桂霞 | Traditional Chinese medicine preparation for treating wind formation from yin deficiency type tourette's syndrome of children |
| CN104127613A (en) * | 2014-06-26 | 2014-11-05 | 黄廷芬 | Traditional Chinese medicine preparation and caring method for treating child Tourette syndrome |
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- 2015-12-14 CN CN201510973632.0A patent/CN105412769A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104127613A (en) * | 2014-06-26 | 2014-11-05 | 黄廷芬 | Traditional Chinese medicine preparation and caring method for treating child Tourette syndrome |
| CN104056078A (en) * | 2014-07-01 | 2014-09-24 | 徐丽丽 | Traditional Chinese medicine preparation for treating tourette syndrome and nursing method |
| CN104055906A (en) * | 2014-07-01 | 2014-09-24 | 马富玲 | Traditional Chinese medicine preparation for treating heart and spleen heat type tourette syndrome |
| CN104096081A (en) * | 2014-07-01 | 2014-10-15 | 王桂霞 | Traditional Chinese medicine preparation for treating wind formation from yin deficiency type tourette's syndrome of children |
Non-Patent Citations (1)
| Title |
|---|
| 冯兆才等: "理脾平肝息风法拟方治疗小儿多发性抽动症60例临床观察", 《中医药临床杂志》 * |
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