CN102894439A - Blood sugar-reducing radix puerariae litchi beverage and its preparation method - Google Patents
Blood sugar-reducing radix puerariae litchi beverage and its preparation method Download PDFInfo
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- CN102894439A CN102894439A CN2011102113316A CN201110211331A CN102894439A CN 102894439 A CN102894439 A CN 102894439A CN 2011102113316 A CN2011102113316 A CN 2011102113316A CN 201110211331 A CN201110211331 A CN 201110211331A CN 102894439 A CN102894439 A CN 102894439A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/77—Sapindaceae (Soapberry family), e.g. lychee or soapberry
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/488—Pueraria (kudzu)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
- A61K36/815—Lycium (desert-thorn)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention relates to a blood sugar-reducing radix puerariae litchi beverage and its preparation method. The beverage is prepared from radix puerariae, litchi seeds, Cortex Lycii and the like. The beverage provided in the invention combines the synergistic effects of radix puerariae, litchi seeds and Cortex Lycii, not only has good mouthfeel, but also can play a blood sugar-reducing role while relieving thirst.
Description
Technical field
The present invention relates to a kind of hypoglycemic Ge Li beverage and preparation method thereof, belong to the plant beverage production technical field.
Background technology
Diabetes are common clinical, frequently-occurring disease, the serious harm human health.The key link for the treatment of diabetes is diet control.Because diet is larger on diabetes blood glucose impact, so such patient except taking the fluctuation of hypoglycemic medicine with control blood sugar, is quite careful and strict control to the absorption of sugar in the diet.
The Sugarless type drink variety that is fit in the market diabetes patients is single, mouthfeel is poor, and the patient is difficult for accepting.Hypoglycemic Ge Li beverage of the present invention has been gathered the root of kudzu vine, semen litchi, the root bark of Chinese wolf-berry, and the three works in coordination with onset, and not only mouthfeel is good, can also play the hypoglycemic effect of falling to the diabetic simultaneously quenching one's thirst.
Summary of the invention
The purpose of this invention is to provide a kind of hypoglycemic Ge Li beverage and preparation method thereof.This beverage not only mouthfeel is good, can also play the hypoglycemic effect of falling to the diabetic simultaneously quenching one's thirst.
The present invention is achieved by the following technical solutions.
A kind of hypoglycemic Ge Li beverage is characterized in that being prepared from by following raw material and weight proportion: 1～40 part of the root of kudzu vine, 1～35 part of semen litchi, 1～35 part of the root bark of Chinese wolf-berry.Preferred weight proportioning of the present invention is: 5～30 parts of the roots of kudzu vine, 4～25 parts of semen litchis, 4～25 parts of the root barks of Chinese wolf-berry.Optimum weight proportioning of the present invention is: 12 parts of the roots of kudzu vine, 10 parts of semen litchis, 10 parts of the root barks of Chinese wolf-berry.
Aforesaid Ge Li beverage is characterized in that also can adding one or more in 1～35 part radix polygonati officinalis, selfheal, balsam pear, Chinese cassia tree or the mulberry leaf in its raw material proportioning.
Aforesaid Ge Li beverage, the source that it is characterized in that described raw material can be Chinese medicine or the extract that is equivalent to Chinese medicine crude drug amount.
Aforesaid Ge Li beverage is characterized in that the preparation method takes by weighing the root of kudzu vine, semen litchi, the root bark of Chinese wolf-berry by recipe quantity, adds 8～15 times of water soakings 0.5 hour, decocted 1～3 hour, medical filtration continues to add 6～12 times of decoctings and boiled 1～2 hour, filter, merging filtrate adds flavouring, adds the purified water allotment, stir, filter, can, sterilization gets final product.
The preparation method of aforesaid Ge Li beverage is characterized in that flavouring is Sugarless type sweetener and lychee flavor; Wherein, the Sugarless type sweetener is any one or more in maltitol, mannitol, D-sorbite, Sucralose, honey element, acesulfame potassium, Aspartame, glycyrrhizin, the stevioside.
The preparation method of aforesaid Ge Li beverage is characterized in that finished dosage forms can also be granule, tablet, capsule, soft capsule, pill, pill or the oral liquid that adopts pharmaceutically acceptable carrier or excipient to make by the pharmacy common process.
The preparation method of aforesaid Ge Li beverage is characterized in that finished product can also be to adopt acceptable excipient or food additives on the food, routinely the various form food made of food preparation technology.
Aforesaid Ge Li beverage is characterized in that preparing the application in blood sugar reducing food or the health products.
Experimental study shows that the Ge Li beverage can reduce experimental hyperglycemia mouse blood sugar level due to the adrenaline, specifically tests as follows:
1 materials and methods
1.1 experiment material and animal
The Ge Li beverage is provided by the side of food, Jiangxi restaurant Chinese medicinal food Co., Ltd.Kunming mouse, body weight 18～22g, the SPF level is provided by University Of Nanchang's Experimental Animal Center, the animal quality certification number: 2009A063 number.
1.2 laboratory apparatus and relevant test solution
The adrenalin hydrochloride parenteral solution: Mingxing Pharmaceuticals Co., Ltd., Guangzhou City provides, lot number: 20100924;
The blood sugar detection kit: Great Wall, Baoding clinical reagent Co., Ltd provides lot number: 20100225;
The dual-beam ultraviolet-uisible spectrophotometer: the Beijing Puxi General Instrument Co., Ltd provides, model: TU-1901;
1.3 experimental technique
Get 50 male mice in kunming, after water 24h is can't help in fasting, be divided at random the basic, normal, high dosage group of blank group, adrenaline model group and Ge Li beverage, 10 every group.Basic, normal, high dosage treated animal is pressed respectively the gastric infusion of 10g crude drug/(kgd), 20g crude drug/(kgd), 40g crude drug/(kgd), every day 1 time, and continuous 14d, blank group, model group give with volume physiological saline.After the last administration, water 10h is can't help in fasting, except blank group intraperitoneal injection of saline, all the other each groups are all by 0.2mg/kg body weight lumbar injection adrenalin hydrochloride parenteral solution, behind the 30min, the mouse orbit veniplex is got blood, presses blood sugar detection kit time-and-motion study blood glucose value.
1.4 data processing method
Experimental data adopts the SPSS statistical software to carry out statistical procedures with " mean ± standard deviation " expression.
2 results
Table 1 Ge Li beverage on the impact of adrenaline hyperglycaemia mouse blood sugar level (
± s)
| Group | Number of animals (only) | Dosage (the g crude drug/(kgd) -1) | Blood glucose value (mmolL -1) |
| Blank group | 10 | - | 5.09±0.62 |
| Model group | 10 | - | 10.75±1.38△ |
| Low dose group | 10 | 10 | 10.66±1.83 |
| Middle dosage group | 10 | 20 | 9.24±1.97* |
| High dose group | 10 | 40 | 7.89±2.04** |
Annotate: compare △ P＜0.01 with the blank group; Compare * P＜0.05, * * P＜0.01 with model group.
This experiment is observed the Ge Li beverage to the impact of experimental hyperglycemia mouse blood sugar level due to the adrenaline, and the clinical experimental basis that provides is provided.Experimental result shows that the model group blood glucose value is higher than the blank group, and the middle and high dosage group of Ge Li beverage can obviously reduce the blood glucose value of experimental hyperglycemia mouse due to the adrenaline, and relatively there were significant differences with model group.Show that the Ge Li beverage has the effect that reduces experimental hyperglycemia mouse blood sugar due to the adrenaline.
The specific embodiment
Further describe the present invention below in conjunction with example:
Embodiment 1
Take by weighing raw material by following weight proportion: 38 parts of the roots of kudzu vine, 33 parts of semen litchis, 32 parts of the root barks of Chinese wolf-berry.
The preparation method: above-mentioned raw materials was added 12 times of water gagings immersions after 0.5 hour, decocted 2.5 hours, medical filtration continues to add 10 times of water gagings and decocted 1 hour, filters, merging filtrate adds Sugarless type sweetener and lychee flavor, adds the purified water allotment, stirs, filter, can, sterilization gets final product.
Aforesaid preparation method is characterized in that the Sugarless type sweetener is any one or more in maltitol, mannitol, D-sorbite, Sucralose, honey element, acesulfame potassium, Aspartame, glycyrrhizin, the stevioside.
Aforesaid preparation method is characterized in that finished dosage forms can also be granule, tablet, capsule, soft capsule, pill, pill or the oral liquid that adopts pharmaceutically acceptable carrier or excipient to make by the pharmacy common process.
Aforesaid preparation method is characterized in that finished product can also be to adopt acceptable excipient or food additives on the food, routinely the various form food made of food preparation technology.
Embodiment 2
Take by weighing raw material by following weight proportion: 2 parts of the roots of kudzu vine, 3 parts of semen litchis, 2 parts of the root barks of Chinese wolf-berry.
The preparation method is with embodiment 1
Embodiment 3
Take by weighing raw material by following weight proportion: 5 parts of the roots of kudzu vine, 5 parts of semen litchis, 4 parts of the root barks of Chinese wolf-berry.
The preparation method is with embodiment 1
Embodiment 4
Take by weighing raw material by following weight proportion: 27 parts of the roots of kudzu vine, 22 parts of semen litchis, 22 parts of the root barks of Chinese wolf-berry.
The preparation method is with embodiment 1
Embodiment 5
Take by weighing raw material by following weight proportion: 12 parts of the roots of kudzu vine, 10 parts of semen litchis, 10 parts of the root barks of Chinese wolf-berry.
The preparation method is with embodiment 1
Embodiment 6
Take by weighing raw material by following weight proportion: 12 parts of the roots of kudzu vine, 10 parts of semen litchis, 10 parts of the root barks of Chinese wolf-berry, 11 parts of radix polygonati officinalis.
The preparation method is with embodiment 1
Embodiment 7
Take by weighing raw material by following weight proportion: 19 parts of the roots of kudzu vine, 17 parts of semen litchis, 8 parts of the root barks of Chinese wolf-berry, 16 parts on mulberry leaf.
The preparation method is with embodiment 1
Embodiment 8
Take by weighing raw material by following weight proportion: 21 parts of the roots of kudzu vine, 18 parts of semen litchis, 12 parts of the root barks of Chinese wolf-berry, 15 parts of selfheals.
The preparation method is with embodiment 1
Embodiment 9
Take by weighing raw material by following weight proportion: 16 parts of the roots of kudzu vine, 10 parts of semen litchis, 9 parts of the root barks of Chinese wolf-berry, 17 parts in balsam pear.
The preparation method is with embodiment 1
Embodiment 10
Take by weighing raw material by following weight proportion: 12 parts of the roots of kudzu vine, 10 parts of semen litchis, 10 parts of the root barks of Chinese wolf-berry, 5 parts of Chinese cassia trees.
The preparation method is with embodiment 1
Embodiment 11
Take by weighing raw material by following weight proportion: 12 parts of the roots of kudzu vine, 10 parts of semen litchis, 10 parts of the root barks of Chinese wolf-berry, 11 parts of selfheals, 10 parts on mulberry leaf.
The preparation method is with embodiment 1
Embodiment 12
Take by weighing raw material by following weight proportion: 15 parts of the roots of kudzu vine, 12 parts of semen litchis, 10 parts of the root barks of Chinese wolf-berry, 8 parts in balsam pear, 20 parts on mulberry leaf, 6 parts of radix polygonati officinalis.
The preparation method is with embodiment 1
Claims (10)
1. a hypoglycemic Ge Li beverage is characterized in that being prepared from by following raw material and weight proportion: 1～40 part of the root of kudzu vine, 1～35 part of semen litchi, 1～35 part of the root bark of Chinese wolf-berry.
2. Ge Li beverage as claimed in claim 1, wherein the weight proportion of each raw material is: 5～30 parts of the roots of kudzu vine, 4～25 parts of semen litchis, 4～25 parts of the root barks of Chinese wolf-berry.
3. Ge Li beverage as claimed in claim 1 or 2, wherein the weight proportion of each raw material is: 12 parts of the roots of kudzu vine, 10 parts of semen litchis, 10 parts of the root barks of Chinese wolf-berry.
4. such as the described Ge Li beverage of claim 1～3, it is characterized in that in its raw material proportioning, also can adding one or more in 1～35 part radix polygonati officinalis, selfheal, balsam pear, Chinese cassia tree or the mulberry leaf.
5. such as the described Ge Li beverage of claim 1～3, the source that it is characterized in that described raw material can be Chinese medicine or the extract that is equivalent to Chinese medicine crude drug amount.
6. such as the described Ge Li beverage of claim 1～3, it is characterized in that the preparation method takes by weighing the root of kudzu vine, semen litchi, the root bark of Chinese wolf-berry by recipe quantity, adds 8～15 times of water soakings 0.5 hour, decocted 1～3 hour, medical filtration continues to add 6～12 times of decoctings and boiled 1～2 hour, filter, merging filtrate adds flavouring, adds the purified water allotment, stir, filter, can, sterilization gets final product.
7. the preparation method of Ge Li beverage as claimed in claim 6 is characterized in that flavouring is Sugarless type sweetener and lychee flavor; Wherein, the Sugarless type sweetener is any one or more in maltitol, mannitol, D-sorbite, Sucralose, honey element, acesulfame potassium, Aspartame, glycyrrhizin, the stevioside.
8. the preparation method of Ge Li beverage as claimed in claim 6, it is characterized in that finished dosage forms can also be any formulation that adopts pharmaceutically acceptable carrier or excipient to make by the pharmacy common process, such as granule, tablet, capsule, soft capsule, pill, pill, oral liquid.
9. the preparation method of Ge Li beverage as claimed in claim 6 is characterized in that finished product can also be to adopt acceptable excipient or food additives on the food, routinely the various form food made of food preparation technology.
10. such as the described Ge Li beverage of claim 1～3, it is characterized in that preparing the application in hypoglycemic food or the health products.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011102113316A CN102894439A (en) | 2011-07-27 | 2011-07-27 | Blood sugar-reducing radix puerariae litchi beverage and its preparation method |
| PCT/CN2012/000991 WO2013013500A1 (en) | 2011-07-27 | 2012-07-24 | Radix puerariae and semen litchi drink for reducing blood glucose and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN2011102113316A CN102894439A (en) | 2011-07-27 | 2011-07-27 | Blood sugar-reducing radix puerariae litchi beverage and its preparation method |
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| Publication Number | Publication Date |
|---|---|
| CN102894439A true CN102894439A (en) | 2013-01-30 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN2011102113316A Pending CN102894439A (en) | 2011-07-27 | 2011-07-27 | Blood sugar-reducing radix puerariae litchi beverage and its preparation method |
Country Status (2)
| Country | Link |
|---|---|
| CN (1) | CN102894439A (en) |
| WO (1) | WO2013013500A1 (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103519306A (en) * | 2013-10-22 | 2014-01-22 | 安徽徽王食品有限公司 | Five-nutlet vegetable protein drink and preparation method thereof |
| CN104225185A (en) * | 2014-09-18 | 2014-12-24 | 安徽科技学院 | Chewing gum with blood sugar reducing function and production method of chewing gum |
| CN105380277A (en) * | 2015-12-15 | 2016-03-09 | 济南舜昊生物科技有限公司 | Health beverage for diabetic patients |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20010018090A1 (en) * | 1999-01-28 | 2001-08-30 | Shinzo Noda | Calorie reducing agent |
| JP2002053475A (en) * | 2000-08-07 | 2002-02-19 | Asahi Breweries Ltd | Glucosidase inhibitor and food or beverage including the same |
| CN1429502A (en) * | 2001-12-29 | 2003-07-16 | 袁茂斌 | Pueraria root beverage |
| CN101467575A (en) * | 2007-10-13 | 2009-07-01 | 朱青 | Hypoglycemic fat-regulating health-care nutrient tea and method for producing the same |
| CN101642529A (en) * | 2009-08-20 | 2010-02-10 | 余东山 | Preparation capable of treating diabetes |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1201776C (en) * | 2002-10-24 | 2005-05-18 | 河北以岭医药研究院有限公司 | Medicines composition for treating diabetes and its prepn |
| CN102038800A (en) * | 2009-10-09 | 2011-05-04 | 吴海洋 | Retained fluid prescription for treating hypertension and preparation method thereof |
-
2011
- 2011-07-27 CN CN2011102113316A patent/CN102894439A/en active Pending
-
2012
- 2012-07-24 WO PCT/CN2012/000991 patent/WO2013013500A1/en active Application Filing
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20010018090A1 (en) * | 1999-01-28 | 2001-08-30 | Shinzo Noda | Calorie reducing agent |
| JP2002053475A (en) * | 2000-08-07 | 2002-02-19 | Asahi Breweries Ltd | Glucosidase inhibitor and food or beverage including the same |
| CN1429502A (en) * | 2001-12-29 | 2003-07-16 | 袁茂斌 | Pueraria root beverage |
| CN101467575A (en) * | 2007-10-13 | 2009-07-01 | 朱青 | Hypoglycemic fat-regulating health-care nutrient tea and method for producing the same |
| CN101642529A (en) * | 2009-08-20 | 2010-02-10 | 余东山 | Preparation capable of treating diabetes |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103519306A (en) * | 2013-10-22 | 2014-01-22 | 安徽徽王食品有限公司 | Five-nutlet vegetable protein drink and preparation method thereof |
| CN104225185A (en) * | 2014-09-18 | 2014-12-24 | 安徽科技学院 | Chewing gum with blood sugar reducing function and production method of chewing gum |
| CN104225185B (en) * | 2014-09-18 | 2017-09-29 | 安徽科技学院 | A kind of hypoglycemic chewing gum and its production method |
| CN105380277A (en) * | 2015-12-15 | 2016-03-09 | 济南舜昊生物科技有限公司 | Health beverage for diabetic patients |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2013013500A1 (en) | 2013-01-31 |
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