CN104055906A - Traditional Chinese medicine preparation for treating heart and spleen heat type tourette syndrome - Google Patents
Traditional Chinese medicine preparation for treating heart and spleen heat type tourette syndrome Download PDFInfo
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- CN104055906A CN104055906A CN201410325326.1A CN201410325326A CN104055906A CN 104055906 A CN104055906 A CN 104055906A CN 201410325326 A CN201410325326 A CN 201410325326A CN 104055906 A CN104055906 A CN 104055906A
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Abstract
The invention discloses a traditional Chinese medicine preparation for treating heart and spleen heat type tourette syndrome. Doctors of all dynasties think that the tourette syndrome is mainly based on liver wind argument, relates to internal organs, particularly liver and is in close relation with heart, spleen and kidney. Therefore, traditional Chinese medicines such as twoleaf swertia herb, littlefruit heartseed fruit, Isodon amethystoides, herpetospermum pedunculosum, Siberian clematis stem, apocynum venetum, common leafflower herb with root, common pearleverlasting herb, longleaf bastardtoadflax herb and delavay honeysuckle herb with the effects of clearing away the heart-fire and relieving spleen heat and calming wind and stopping spasm are decocted into decoction. The clinical test in the institute proves that the total effective rate is 92.0 percent and is obviously superior to 68.0 in the control group, and the traditional Chinese medicine preparation has an obvious curative effect and is worthy of clinical popularization and application.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, relate in particular to a kind of Chinese medicine preparation for the treatment of accumulation of heat in the heart and spleen type Tourette syndrome.
Background technology
Multiple pumping symptoms claims again syndrome of bawdry and twitching of children, is a kind of chronic neuropsychological obstacle disease of complexity, clinically mainly take suddenly, independently motion twitch and or vocal tics be feature, often with behavior and the dysthymic disorder such as moving, force more.Along with social development, primary disease morbidity is the trend increasing gradually.The cognitive questions such as Tourette syndrome often follows that mental act is abnormal, attention and memory impairment, have a strong impact on child's study, life and social activity, the social activity such as bring heavy psychological burden to infants ' parents, the state of an illness of part infant can extend to adult, the following employment of impact.This sick common drug of western medical treatment has haloperidol, Tai Bili, but its side effect is more obvious, as slow in one's movements, muscular tension enhancing, difficulty in opening mouth etc., therefore takes trihexyphenidyl to reduce its side effect simultaneously.Applicant proves through clinical practice for many years, treatment by Chinese herbs primary disease has obvious curative effects, improving clinical symptoms, shorten the course of disease, improve infant quality of life, avoid the aspects such as adverse effect to be all obviously better than Western medicine, be one of current tcm clinical study hotspot.
Summary of the invention
The object of this invention is to provide a kind of Chinese medicine preparation for the treatment of accumulation of heat in the heart and spleen type Tourette syndrome.The meridians close relation of taste and the heart contacts, taste dependent territory, the heart matches fire, the heart in taste, be mother child relation.If son and female, can involve the heart because of the imbalance of taste.Ancient Chinese medicine doctor thinks that children with multiple twitches that card is many is seted forth one's views by " liver-wind ", relates to internal organs and is mainly liver, in close relations with the heart, spleen, kidney.Dialectical treatment is with the purgation of spleen excess that clears away heart-fire, and endogenous wind stopping relieving convulsion is principle.
The object of the invention is to be achieved through the following technical solutions, the Chinese medicine preparation of this treatment accumulation of heat in the heart and spleen type Tourette syndrome is made by the Chinese medicine of following weight portion: Herba Swertiae heteranthae 3-5 part, Fructus Cardiospermi microcarpi 2-4 part, Herba Rabdosiae glaucocalycis 5-9 part, Fructus Herpetospermi pedunculosi 2-5 part, Caulis clematidis sibiricae 2-4 part, Herba Apocyni veneti 2-5 part, Herba Phyllanthi Urinariae 3-8 part, Herba Anaphalidis Margaritaceae 10-20 part, Herba Thesii Longifolii 3-5 part, Herba lonicerae delavayi 3-6 part.
Preferably, 4 parts of Herba Swertiae heteranthaes, 3 parts of Fructus Cardiospermi microcarpis, 7 parts of Herba Rabdosiae glaucocalycis, 3 parts of Fructus Herpetospermi pedunculosi, 3 parts of Caulis clematidis sibiricaes, 3 parts of Herba Apocyni venetis, 5 parts of Herba Phyllanthi Urinariaes, 15 parts of Herba Anaphalidis Margaritaceaes, 4 parts of Herba Thesii Longifoliis, 4 parts of Herba lonicerae delavayis.
Preparation method is made decoction by above-mentioned Chinese medicine decocting.
In side: Herba Swertiae heteranthae suppressing liver-wind, nourish blood, regulating menstruation, heart tonifying; Fructus Cardiospermi microcarpi expelling wind to relieve convulsion, removing toxic substances; Herba Rabdosiae glaucocalycis heat-clearing and toxic substances removing, spleen invigorating, help digestion, invigorate blood circulation; Fructus Herpetospermi pedunculosi heat-clearing and toxic substances removing, easing the affected liver; Caulis clematidis sibiricae clearing away heart-fire, rush down damp and hot, promoting blood circulation; Herba Apocyni veneti clearing away heat-fire, heart tonifying diuresis, blood pressure lowering; Herba Phyllanthi Urinariae liver heat removing and eyesight improving, eliminating dampness by diuresis diuresis, removing toxic substances; Herba Anaphalidis Margaritaceae heat clearing and damp drying, pathogenic fire purging are dispeled the wind; Herba Thesii Longifolii expelling wind and clearing away heat, spasmolytic; Relieving convulsion, removing toxic substances that Herba lonicerae delavayi dispels the wind.
Clinical data
1, physical data selects in January, 2010～2012 year December at my the Out-patient Department 50 children of seing patients, and is divided at random treatment group 25 examples, matched group 25 examples by medical sequencing.In treatment group 25 examples, male 13 examples, female's 12 examples, at 4～12 years old age, the mean age is 7.5 years old; The course of disease 10 months～3 years 2 months, average course of disease is 1 year 1 month.In matched group 25 examples, male 11 examples, female's 14 examples; At 4 years old 7 months～11 years old age, the mean age is 7.9 years old; The course of disease 11 months～3 years 11 months, average course of disease is 1 year 2 months.Epidemiological Analysis by statistics, 2 groups of infants there was no significant difference aspect age, sex, the course of disease, has comparability.
2, diagnostic criteria diagnostic criteria with the relevant multiple pumping symptoms of the 3rd edition > > of diagnostic criteria 6 with reference to < < Chinese Spirit classification of diseases scheme: (1) onset is before 18 years old, and symptom can extend to adult.(2) main manifestations is that multi-motion is twitched and one or more not sounding twitches, mostly is complexity and twitches, and how the two occurs simultaneously.(3) twitch symptom and almost occur everyday, 1 day repeatedly, at least continues more than 1 year.Or be interrupted generation, and in 1 year, remission is no more than 2 months.(4) twitch and can control by will, descending aggravation, during sleep, disappear.(5) this obstacle causes daily life and social function obviously impaired, and it is very painful and worried that infant is felt.(6) that can not explain with other reasons does not independently twitch or sounding.Wherein (1), (2), (3), (6) indispensability, can determine diagnosis with reference to (4), (5).
Accumulation of heat in the heart and spleen type diagnostic criteria: (according to actual clinical performance, certainly intending diagnostic criteria as follows) main symptom: frown, blink, shake the head, shrug, the twitch of extremity, trunk different parts, even obscene words.Inferior card: vexed uneasiness, night is sleeping not peaceful, xerostomia wish drink, oliguria with yellow urine, large dry stool or normal, red tongue point is red, yellow and thin fur or greasy, all diseases such as stringy and rolling pulse number.(above main symptom possesses 1, possesses 3 or above person in inferior disease, and getting final product dialectical is accumulation of heat in the heart and spleen type.)
3, Therapeutic Method treatment group is taken Chinese medicine preparation of the present invention, takes Herba Swertiae heteranthae 4g, Fructus Cardiospermi microcarpi 3g, Herba Rabdosiae glaucocalycis 7g, Fructus Herpetospermi pedunculosi 3g, Caulis clematidis sibiricae 3g, Herba Apocyni veneti 3g, Herba Phyllanthi Urinariae 5g, Herba Anaphalidis Margaritaceae 15g, Herba Thesii Longifolii 4g, Herba lonicerae delavayi 4g.1 dose of every day, day decocts 2 times, fried liquid 200m1, and a minute morning and evening takes for twice.Matched group is taken tiapride sheet: 4～7 years old, and 1/3 piece/times; 7～12 years old, 1/2 piece/times; More than 12 years old, 1 piece/times, all administration every day is 2 times; All take 1 month as a course for the treatment of for two groups, treat 2 courses for the treatment of, observe its curative effect, follow up a case by regular visits to 6 months.
Treatment Tourette syndrome needs wholistic therapy, except Drug therapy, the close fit that also needs the head of a family and doctor, the head of a family must note the adjusting of infant emotion and daily life system, note exchanging with child, alleviate the stress of infant, for it, create a loose environment, if infant bears a grudge, must allow it lead off out.Also to control infant and see less TV, Play Station games not, not see the program of plot tense and stimulation especially as far as possible.Respect the sense of personal worth of infant, in the presence of stranger's face, do not criticize infant, should in secret give good will and remind, to alleviate its thought pressure.The infant state of an illness is taken a favorable turn and should be given encouragement in good time, to improve the confidence of infant cure diseases.
4, criterion of therapeutical effect recovery from illness: through treatment twitch, obscene words, disappear completely, nothing recurrence in 2a; Effective: through treatment twitch, obscene words disappear, in flu or recurrence when excited, and the more original action of action alleviates one-level; Effective: through treatment twitch, obscene words alleviate one-level, flu or when excited repeatedly, action as front or increase the weight of one-level; Invalid: the state of an illness is improved not obvious.
5, therapeutic outcome patient treatment observe the curative effect after 2 courses for the treatment of, treatment group 25 examples, 13 examples of wherein fully recovering (52.0%), effective 7 examples (28.0%), 3 examples (12.0%) that take a turn for the better, invalid 2 examples (8.0%), total effective rate 92.0%.Matched group 25 examples, 3 examples of wherein fully recovering (12.0%), effective 5 examples (20.0%), 9 examples (36.0%) that take a turn for the better, invalid 8 examples (32.0%), total effective rate 68.0%.Two groups of total effective rate comparing differences have significant (P < 0.05), and treatment group therapeutic effect is obviously better than matched group.In therapeutic process, treatment group infant does not have obvious adverse reaction, and in matched group infant, drowsiness symptom appears in 5 examples, and digestive tract reaction and dizziness, the symptom such as weak appear in 3 examples, and after drug withdrawal, symptom fades away.
6, model case Wang, man, 7 years old, on May 2nd, 2011 was medical.Infant is frequently blinked, is shaken the head, and shrugs, and 3 months, absent minded, mood was irritated, irritability, and crouch not peaceful night, xerostomia wish drink, and stool is slightly dry, day 1 time, yellow urine, red tip of the tongue, yellow and thin fur, wiry and frequent pulse.Be Tourette syndrome after diagnosing, look into electroencephalogram roughly normal, severity extent is moderate.Analyze infant irascible temperament, susceptible to lose temper due to restlessness, night is sleeping not peaceful, and due to hyperactivity of heart-fire, infant is had a liking for food delicious food savoury, maror usually in addition, and snacks are continuous, and dysfunction of the spleen in transportation accumulates the heat-transformation of accumulating in the course of time, extreme heat causing wind syndrome in expectorant is turbid.Dialectical genus accumulation of heat in the heart and spleen.Control the purgation of spleen excess that clears away heart-fire, endogenous wind stopping relieving convulsion.Herba Swertiae heteranthae 4g, Fructus Cardiospermi microcarpi 3g, Herba Rabdosiae glaucocalycis 7g, Fructus Herpetospermi pedunculosi 3g, Caulis clematidis sibiricae 3g, Herba Apocyni veneti 3g, Herba Phyllanthi Urinariae 5g, Herba Anaphalidis Margaritaceae 15g, Herba Thesii Longifolii 4g, Herba lonicerae delavayi 4g for side.Be decocted in water for oral dose, 1 day 1 dose, take at twice, serve on 2 weeks.Advise its head of a family to reduce infant learning pressure as far as possible, give light diet, the living environment of Creating Comfort.Two examine: the frequency of blinking, shake the head obviously alleviates before, and the symptom of shrugging disappears substantially, and vexed alleviating slept and feel unwell night, xerostomia, food receive can, stool is normal, day 1 time, urine is slightly yellow.Take continuously after 2 weeks, the symptoms such as twitch are obviously alleviated.Adhere to taking medicine about 2 months, state of an illness recovery from illness, follows up a case by regular visits to and does not recur half a year.
The specific embodiment
Embodiment mono-: take Herba Swertiae heteranthae 4g, Fructus Cardiospermi microcarpi 3g, Herba Rabdosiae glaucocalycis 7g, Fructus Herpetospermi pedunculosi 3g, Caulis clematidis sibiricae 3g, Herba Apocyni veneti 3g, Herba Phyllanthi Urinariae 5g, Herba Anaphalidis Margaritaceae 15g, Herba Thesii Longifolii 4g, Herba lonicerae delavayi 4g, above-mentioned Chinese medicine decocting is become to decoction.
Embodiment bis-: take Herba Swertiae heteranthae 5g, Fructus Cardiospermi microcarpi 2g, Herba Rabdosiae glaucocalycis 9g, Fructus Herpetospermi pedunculosi 2g, Caulis clematidis sibiricae 4g, Herba Apocyni veneti 2g, Herba Phyllanthi Urinariae 8g, Herba Anaphalidis Margaritaceae 10g, Herba Thesii Longifolii 5g, Herba lonicerae delavayi 3g, above-mentioned Chinese medicine decocting is become to decoction.
Embodiment tri-: take Herba Swertiae heteranthae 3g, Fructus Cardiospermi microcarpi 4g, Herba Rabdosiae glaucocalycis 5g, Fructus Herpetospermi pedunculosi 5g, Caulis clematidis sibiricae 2g, Herba Apocyni veneti 5g, Herba Phyllanthi Urinariae 3g, Herba Anaphalidis Margaritaceae 20g, Herba Thesii Longifolii 3g, Herba lonicerae delavayi 6g, above-mentioned Chinese medicine decocting is become to decoction.
Claims (2)
1. treat a Chinese medicine preparation for accumulation of heat in the heart and spleen type Tourette syndrome, it is characterized in that this Chinese medicine preparation made by the Chinese medicine of following weight portion: Herba Swertiae heteranthae 3-5 part, Fructus Cardiospermi microcarpi 2-4 part, Herba Rabdosiae glaucocalycis 5-9 part, Fructus Herpetospermi pedunculosi 2-5 part, Caulis clematidis sibiricae 2-4 part, Herba Apocyni veneti 2-5 part, Herba Phyllanthi Urinariae 3-8 part, Herba Anaphalidis Margaritaceae 10-20 part, Herba Thesii Longifolii 3-5 part, Herba lonicerae delavayi 3-6 part.
2. a kind of Chinese medicine preparation for the treatment of accumulation of heat in the heart and spleen type Tourette syndrome according to claim 1, is characterized in that this Chinese medicine preparation made by the Chinese medicine of following weight portion: 4 parts of Herba Swertiae heteranthaes, 3 parts of Fructus Cardiospermi microcarpis, 7 parts of Herba Rabdosiae glaucocalycis, 3 parts of Fructus Herpetospermi pedunculosi, 3 parts of Caulis clematidis sibiricaes, 3 parts of Herba Apocyni venetis, 5 parts of Herba Phyllanthi Urinariaes, 15 parts of Herba Anaphalidis Margaritaceaes, 4 parts of Herba Thesii Longifoliis, 4 parts of Herba lonicerae delavayis.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105412769A (en) * | 2015-12-14 | 2016-03-23 | 沈彤 | Traditional Chinese medicine preparation for treating phlegmatic hygrosis orifice blocking type multiple tic disorder of children |
| CN107126510A (en) * | 2017-05-09 | 2017-09-05 | 上海市中医医院 | A kind of Chinese medicine composition for treating child tic disorder syndrome and its application |
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| WO2004006944A1 (en) * | 2002-07-12 | 2004-01-22 | Harvey Clare G | Flower essence-containing medicaments |
| CN101301430A (en) * | 2008-06-03 | 2008-11-12 | 陈德顺 | Decoction for treating blood deficiency type neurasthenic |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2004006944A1 (en) * | 2002-07-12 | 2004-01-22 | Harvey Clare G | Flower essence-containing medicaments |
| CN101301430A (en) * | 2008-06-03 | 2008-11-12 | 陈德顺 | Decoction for treating blood deficiency type neurasthenic |
Non-Patent Citations (1)
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| 杨家茂等: "儿科杂病辨治琐谈", 《中医儿科杂志》 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105412769A (en) * | 2015-12-14 | 2016-03-23 | 沈彤 | Traditional Chinese medicine preparation for treating phlegmatic hygrosis orifice blocking type multiple tic disorder of children |
| CN107126510A (en) * | 2017-05-09 | 2017-09-05 | 上海市中医医院 | A kind of Chinese medicine composition for treating child tic disorder syndrome and its application |
| CN107126510B (en) * | 2017-05-09 | 2020-11-27 | 上海市中医医院 | Traditional Chinese medicine composition for treating children tic disorder syndrome and application thereof |
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| CN104055906B (en) | 2016-05-18 |
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Inventor after: Ma Fuling Inventor after: Tan Hongzhen Inventor before: Ma Fuling |
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Effective date of registration: 20170517 Address after: 226100, No. 588, Jinyang Road, Yue Yue town, Haimen, Jiangsu, Nantong Patentee after: Haimen Yue Yue Textile Co., Ltd. Address before: 276400 Linyi health center, Yishui, Shandong, China, Yishui Central Hospital, No. 17, Patentee before: Ma Fuling |
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