CN104055906B - A kind of Chinese medicine preparation for the treatment of accumulation of heart and spleen type Tourette syndrome - Google Patents
A kind of Chinese medicine preparation for the treatment of accumulation of heart and spleen type Tourette syndrome Download PDFInfo
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Abstract
The invention discloses a kind of Chinese medicine preparation for the treatment of accumulation of heart and spleen type Tourette syndrome, the invention belongs to the field of Chinese medicines. Ancient Chinese medicine doctor thinks that children with multiple twitches that card is many is seted forth one's views by " liver wind ", relates to internal organs and is mainly liver, in close relations with the heart, spleen, kidney. The present invention selects to have to clear away heart-fire to rush down spleen for this reason, breath wind stops Chinese medicine twoleaf swertia herb, littlefruit heartseed fruit, Rabdosia amethystoides, herpetospermum pedunculosum, siberian clematis stem, bluish dogbane, Sagina subulata, common pearleverlasting herb, longleaf bastardtoadflax herb, the Lonicera gigantea of convulsion, decocting becomes decoction, through the court's clinical testing, total effective rate 92.0%, is obviously better than control group 68.0%.
Description
Technical field
The present invention relates to a kind of Chinese medicine composition, relate in particular to one and treat accumulation of heart and spleenThe Chinese medicine preparation of type Tourette syndrome.
Background technology
Multiple pumping symptoms claims again syndrome of bawdry and twitching of children, is a kind of complexityChronic neuropsychological obstacle disease, clinical mainly with suddenly, not independently motion take outMoving and or vocal tics be feature, often with behavior and the mood barrier such as moving, force moreHinder. Along with social development, the morbidity of this disease is the trend increasing gradually. Children with multipleProperty Gilles de la Tourette's syndrome often follow that mental act is abnormal, the cognitive question such as attention and memory impairment,Have a strong impact on children's study, life and social activities, bring heavy to infants ' parentsPsychological burden, the state of an illness of part infant can extend to adult, the following employment of impact etc.Social activities. This sick common drug of western medical treatment has haloperole, Tai Bili, but itsSide effect is more obvious, as slow in one's movements, the enhancing of flesh tension force, difficulty in opening mouth etc., thereforeTake artane to reduce its side effect simultaneously. Applicant demonstrate,proves through clinical practice for many yearsBright, this disease for the treatment of by Chinese herbs has obvious curative effects, improve clinical symptoms, shorten the course of disease,Improve infant quality of life, avoid the aspects such as adverse drug reaction to be all obviously better than Western medicine,It is one of current tcm clinical study hotspot.
Summary of the invention
The object of this invention is to provide one and treat the twitch of accumulation of heart and spleen type children with multipleThe Chinese medicine preparation of disease. The channels and collaterals close relation of taste and the heart contacts, taste dependent territory, the heartBelong to fire, the heart be mother-child relationship (MCR) in taste. If son and female, can be because of the imbalance of tasteInvolve the heart. Ancient Chinese medicine doctor thinks that children with multiple twitch card is many by " liver wind " argument,Relate to internal organs and be mainly liver, in close relations with the heart, spleen, kidney. Dialectical treatment is to clear away heart-fireRush down spleen, it is principle that breath wind stops convulsion.
The object of the invention is to be achieved through the following technical solutions, this treatment heart spleen is long-pendingThe Chinese medicine preparation of pattern of fever Tourette syndrome is made up of the Chinese medicine of following weight portion:Twoleaf swertia herb 3-5 part, littlefruit heartseed fruit 2-4 part, Rabdosia amethystoides 5-9 part, herpetospermum pedunculosum 2-5 part,Siberian clematis stem 2-4 part, bluish dogbane 2-5 part, Sagina subulata 3-8 part, common pearleverlasting herb10-20 part, longleaf bastardtoadflax herb 3-5 part, Lonicera gigantea 3-6 part.
Preferably, 4 parts of twoleaf swertia herbs, 3 parts of littlefruit heartseed fruits, 7 parts of Rabdosia amethystoides, herpetospermum pedunculosum 3Part, 3 parts of siberian clematis stems, 3 parts of bluish dogbanes, 5 parts of Sagina subulatas, common pearleverlasting herb 15Part, 4 parts of longleaf bastardtoadflax herbs, 4 parts of Lonicera giganteas.
Above-mentioned Chinese medicine decocting is made decoction by preparation method.
Fang Zhong: twoleaf swertia herb suppressing liver-wind, nourish blood, menstruation regulating, cardiac stimulant; The littlefruit heartseed fruit solution of dispeling the windConvulsion, removing toxic substances; Rabdosia amethystoides is clearing heat and detoxicating, invigorating the spleen, help digestion, invigorate blood circulation; Herpetospermum pedunculosum heat-clearingRemoving toxic substances, soft liver; Siberian clematis stem clearing away the heart-fire, rush down damp and hot, promoting blood circulation; Bluish dogbane heat-clearingPurging intense heat, cardiac stimulant diuresis, hypotensive; Sagina subulata clears liver and improve vision, excreting dampness diuresis, removing toxic substances;Common pearleverlasting herb heat-clearing and damp-drying drug, purging intense heat are dispeled the wind; Longleaf bastardtoadflax herb expelling wind and clearing away heat, spasmolysis; GreatlyRelieving convulsion, removing toxic substances that honeysuckle is dispeled the wind.
Clinical data
1, physical data selects in January, 2010～2012 year December at my gateExamine the 50 children of seing patients, be divided at random treatment group 25 examples by medical sequencing,Control group 25 examples. In treatment group 25 examples, male 13 examples, female's 12 examples, age 4～12In year, the mean age is 7.5 years old; The course of disease 10 months～3 years 2 months, average course of disease is1 year 1 month. In control group 25 examples, male 11 examples, female's 14 examples; 7 of 4 years old agesMonth～11 years old, the mean age is 7.9 years old; The course of disease 11 months～3 years 11 months, flatAll the course of disease is 1 year 2 months. Epidemiological Analysis by statistics, 2 groups of infants age, sex,Course of disease aspect there was no significant difference, has comparativity.
2, diagnostic criteria is with reference to " Chinese Spirit classification of diseases scheme and diagnostic criteria6 the 3rd editions " the diagnostic criteria of relevant multiple pumping symptoms: (1) onset was in 18 years oldBefore, symptom can extend to adult. (2) main manifestations is that multi-motion is twitched and oneOr multiple not sounding twitch, mostly be complexity and twitch, the two many appearance simultaneously. (3)Twitch symptom and almost occur everyday, 1 day repeatedly, at least continued more than 1 year. OrDisconnected generation, and in 1 year, remission is no more than 2 months. (4) twitching can be in short-termInside be subject to will control, descending aggravation, when sleep, disappear. (5) this obstacle causes dayNormal life and social function are obviously impaired, and it is very painful and worried that infant is felt. (6)That can not explain with other reasons does not independently twitch or sounding. Wherein (1), (2),(3), (6) indispensability, with reference to (4), (5) determining diagnosis.
Accumulation of heart and spleen type diagnostic criteria: (according to actual clinical performance, certainly intend diagnostic criteriaAs follows) main symptom: frown, blink, shake the head, shrug, four limbs, trunk different partsTwitch, even obscene words. Inferior card: vexed uneasiness, night is sleeping not peaceful, dry wish drink,Oliguria with yellow urine, stool is dry or normal, and the red point of tongue is red, the thin Huang of tongue or greasy, wiry and rolling pulse numberEtc. all diseases. (above main symptom possesses 1, possesses 3 or above person, in inferior diseaseCan dialectically be accumulation of heart and spleen type. )
3, methods for the treatment of treatment group is taken Chinese medicine preparation of the present invention, takes crowGold careless 4g, littlefruit heartseed fruit 3g, Rabdosia amethystoides 7g, herpetospermum pedunculosum 3g, siberian clematis stem 3g, sieveCloth fiber crops 3g, Sagina subulata 5g, common pearleverlasting herb 15g, longleaf bastardtoadflax herb 4g, Lonicera gigantea 4g.1 dose of every day, day decocts 2 times, fried liquid 200m1, and a point morning and evening takes for twice. Control groupTake Tiapride sheet: 4～7 years old, 1/3 piece/times; 7～12 years old, 1/2 piece/times; 12More than year, 1 piece/times, all administrations every day 2 times; Two groups all taking 1 month as one treatmentJourney, treats 2 courses for the treatment of, observes its curative effect, follows up a case by regular visits to 6 months.
Treatment Tourette syndrome needs wholistic therapy, except medicine treatment, alsoNeed the head of a family and doctor's close fit, the head of a family must note infant mood and lifeThe adjusting of work and rest, note exchanging with child, alleviates the stress of infant, is itCreate a loose environment, must allow it lead off if infant bears a grudgeCome. Also to control infant and see less TV, Play Station games not, not see plot especially as far as possibleIntense and stimulative program. Respect the self-esteem of infant, do not criticize in the presence of stranger's faceInfant, should in secret give good will and remind, to alleviate its thought pressure. To infant diseaseFeelings take a favorable turn and should give encouragement in good time, to improve the confidence of infant cure diseases.
4, criterion of therapeutical effect recovery from illness: disappear completely through treatment twitch, obscene words, in 2aWithout recurrence; Effective: through treatment twitch, obscene words disappear, in flu or when excitedRecurrence, and the more original action of action alleviates one-level; Effective: through treatment twitch, obscene wordsAlleviate one-level, flu or when excited repeatedly, action as front or increase the weight of one-level;Invalid: the state of an illness is improved not obvious.
5, observe the curative effect after 2 courses for the treatment of of treatment results patient treatment, treatment group 25 examples,13 examples of wherein fully recovering (52.0%), effective 7 examples (28.0%), 3 examples that take a turn for the better (12.0%),Invalid 2 examples (8.0%), total effective rate 92.0%. Control group 25 examples, 3 examples of wherein fully recovering(12.0%), effective 5 examples (20.0%), 9 examples that take a turn for the better (36.0%), invalid 8 examples (32.0%),Total effective rate 68.0%. Two groups of total effective rate comparing differences have significant (P <0.05), treatment group result for the treatment of is obviously better than control group. In therapeutic process, treatment group is suffered fromYoungster does not have obvious adverse reaction, and in control group infant, drowsiness symptom, 3 examples appear in 5 examplesOccur digestive tract reaction and dizziness, the symptom such as weak, after drug withdrawal, symptom fades away.
6, model case Wang, man, 7 years old, on May 2nd, 2011 was medical.Infant is frequently blinked, is shaken the head, shrugs, and 3 months, absent minded, mood agitation,Irritability, crouch not peaceful night, dry wish drink, stool is slightly dry, day 1 time, urine Huang, tonguePoint is red, the thin Huang of tongue, wiry and frequent pulse. Be Tourette syndrome after diagnosing, look into brain electricityScheme roughly normally, severity extent is moderate. Analysis infant is edgy, dysphoria,Night is sleeping not peaceful, and due to heart-fire hyperactivity, infant is had a liking for food delicious food savoury, pungent usually in additionPeppery food, snacks are continuous, and the dysfunction of the spleen in transport is accumulate in phlegm is turbid, the heat-transmission of accumulating in the course of time, thermoae lifeWind. Dialectical genus accumulation of heart and spleen. Control to clear away heart-fire and rush down spleen, breath wind stops convulsion. Side's twoleaf swertia herb4g, littlefruit heartseed fruit 3g, Rabdosia amethystoides 7g, herpetospermum pedunculosum 3g, siberian clematis stem 3g, bluish dogbane3g, Sagina subulata 5g, common pearleverlasting herb 15g, longleaf bastardtoadflax herb 4g, Lonicera gigantea 4g. WaterDecoction, 1 day 1 dose, take at twice, serve on 2 weeks. Advise its head of a family to reduce and suffer from as far as possibleYoungster's learning pressure, gives bland diet, the living environment of Creating Comfort. Two examine: blinkEye, the frequency of shaking the head obviously alleviate before, and the symptom of shrugging disappears substantially, vexed alleviating,Sleep night and feel unwell, dry, food receive can, stool is normal, day 1 time, urine is slightly yellow. ConnectContinuous taking after 2 weeks, the symptoms such as twitch are obviously alleviated. Adhere to taking medicine about 2 months,State of an illness recovery from illness, follows up a case by regular visits to and does not recur half a year.
Detailed description of the invention
Embodiment mono-: take twoleaf swertia herb 4g, littlefruit heartseed fruit 3g, Rabdosia amethystoides 7g, herpetospermum pedunculosum3g, siberian clematis stem 3g, bluish dogbane 3g, Sagina subulata 5g, common pearleverlasting herb 15g, nineCelestial careless 4g, Lonicera gigantea 4g, become decoction by above-mentioned Chinese medicine decocting.
Embodiment bis-: take twoleaf swertia herb 5g, littlefruit heartseed fruit 2g, Rabdosia amethystoides 9g, herpetospermum pedunculosum2g, siberian clematis stem 4g, bluish dogbane 2g, Sagina subulata 8g, common pearleverlasting herb 10g, nineCelestial careless 5g, Lonicera gigantea 3g, become decoction by above-mentioned Chinese medicine decocting.
Embodiment tri-: take twoleaf swertia herb 3g, littlefruit heartseed fruit 4g, Rabdosia amethystoides 5g, herpetospermum pedunculosum5g, siberian clematis stem 2g, bluish dogbane 5g, Sagina subulata 3g, common pearleverlasting herb 20g, nineCelestial careless 3g, Lonicera gigantea 6g, become decoction by above-mentioned Chinese medicine decocting.
Claims (2)
1. treat a Chinese medicine preparation for accumulation of heart and spleen type Tourette syndrome, itsBe characterised in that this Chinese medicine preparation is made up of the Chinese medicine of following weight portion: twoleaf swertia herb 3-5 part,Littlefruit heartseed fruit 2-4 part, Rabdosia amethystoides 5-9 part, herpetospermum pedunculosum 2-5 part, siberian clematis stem 2-4Part, bluish dogbane 2-5 part, Sagina subulata 3-8 part, common pearleverlasting herb 10-20 part, nineCelestial careless 3-5 part, Lonicera gigantea 3-6 part.
2. one according to claim 1 is treated accumulation of heart and spleen type children with multipleThe Chinese medicine preparation of Gilles de la Tourette's syndrome, is characterized in that this Chinese medicine preparation is by following weight portionMedicine is made: 4 parts of twoleaf swertia herbs, 3 parts of littlefruit heartseed fruits, 7 parts of Rabdosia amethystoides, 3 parts of herpetospermum pedunculosum,3 parts of siberian clematis stems, 3 parts of bluish dogbanes, 5 parts of Sagina subulatas, 15 parts of common pearleverlasting herbs,4 parts of longleaf bastardtoadflax herbs, 4 parts of Lonicera giganteas.
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| CN107126510B (en) * | 2017-05-09 | 2020-11-27 | 上海市中医医院 | Traditional Chinese medicine composition for treating children tic disorder syndrome and application thereof |
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