CN105412767A - Sterilization oral liquid for treating ordinary hand-foot-mouth disease - Google Patents
Sterilization oral liquid for treating ordinary hand-foot-mouth disease Download PDFInfo
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Abstract
The invention belongs to the technical field of traditional Chinese medicines and in particular relates to sterilization oral liquid for treating ordinary hand-foot-mouth disease. The sterilization oral liquid for treating ordinary hand-foot-mouth disease is prepared from the following raw materials: herba andrographitis, bitter herbs, blackberrylily rhizome, fructus gardenia, herb of whiteflower violet, semiaquilegia root, burdock root, Hedge Prinsepia Nrt, iris wattii, Semen Alpiniae Katsumadai, talc and medulla tetrapanacis . The oral liquid has the characteristics of rapid effect of treating ordinary hand-foot-mouth disease, excellent effect, large safety range and few adverse effects, and is convenient to take and low in cost, and is worthy of clinical popularization.
Description
Technical field
The invention belongs to the technical field of Chinese medicine, be specifically related to a kind of sterilization oral liquid for the treatment of plain edition hand-foot-mouth disease.
Background technology
Hand-foot-mouth disease is the Class C infectious disease caused by multiple enterovirus, is multiplely born in preschooler, especially the highest with less than 3 years old age group sickness rate.Can cause the principal character of the herpes such as hands, foot, oral cavity and buttocks and heating, small number of patients can merge pulmonary edema, myocarditis and the complication such as aseptic meningitis, encephalitis.This disease transmission is strong, and disease progression is fast, and case fatality rate is higher, a clinical more thorny problem in recent years, particularly this year disease time in advance, characteristics of incidence is inconsistent, be not true to type, transfer to serious symptom, dead patient ratio higher, sickness rate etc. are all on the rise.
Hand-foot-mouth disease divides plain edition hand-foot-mouth disease case and serious symptom hand-foot-mouth disease case.Plain edition hand-foot-mouth disease case only shows hand-foot-mouth disease or buttocks erythra, certainly also has part infant only in some or two visible erythra of part, loses erythra, only have fever when also having some cases to start, and crosses 2-3 talent and plays erythra.
Current doctor trained in Western medicine there is no specific medicament, mainly anti symptom treatment.Chinese medicine is thought, hand-foot-mouth disease belongs to " epidemic febrile disease " category, and plain edition General Symptoms does not weigh, by time row epidemic disease poisons mouth and nose and entering, toxic dampness and heat is sent out in brothers, smokes in oropharynx, thoroughly in skin, sends out as herpes.Controlling should heat-clearing and toxic substances removing, wind-dispelling heat-dissipating, removing dampness expelling pathogenic factors from the exterior.
Summary of the invention
The object of the invention is to the defect for above-mentioned existence and provide a kind of sterilization oral liquid for the treatment of plain edition hand-foot-mouth disease, it is rapid-action, effective that this oral liquid has the common hand-foot-mouth disease for the treatment of, the features such as safety range is large, and untoward reaction is few, and medication is convenient, low price, clinic is promoted.
Technical scheme of the present invention is: a kind of sterilization oral liquid for the treatment of plain edition hand-foot-mouth disease, is made up of following raw material: golden Rhizoma et radix valerianae, swallow clothing, black Wooden-fan, more Fructus Persicae, Herba violae patrinii, Radix Semiaquilegiae, Mus are glued root, white Rui core, Herba adianti myriosori, fly Lei Zi, kind stone and five jiaos of Cortex Acanthopanacis Radicis.
The sterilization oral liquid of described treatment plain edition hand-foot-mouth disease, is made up of the raw material of following weight portion: golden Rhizoma et radix valerianae 10-18 part, swallow clothing 20-30 part, black Wooden-fan 16-21 part, more Fructus Persicae 12-23 part, Herba violae patrinii 10-18 part, the sub-26-31 part of Radix Semiaquilegiae, Mus are glued root 11-19 part, white Rui core 9-15 part, Herba adianti myriosori 26-35 part, fly Lei Zi 8-14 part, kind stone 6-15 part and five jiaos of Cortex Acanthopanacis Radicis 7-19 parts.
The sterilization oral liquid of described treatment plain edition hand-foot-mouth disease, is made up of the raw material of following weight portion: golden Rhizoma et radix valerianae 12-16 part, swallow clothing 23-28 part, black Wooden-fan 18-20 part, more Fructus Persicae 14-21 part, Herba violae patrinii 13-17 part, the sub-27-30 part of Radix Semiaquilegiae, Mus are glued root 13-17 part, white Rui core 11-14 part, Herba adianti myriosori 27-32 part, fly Lei Zi 10-12 part, kind stone 8-11 part and five jiaos of Cortex Acanthopanacis Radicis 8-17 parts.
The sterilization oral liquid of described treatment plain edition hand-foot-mouth disease, is made up of the raw material of following weight portion: golden Rhizoma et radix valerianae 14 parts, 26 parts, swallow clothing, black Wooden-fan 19 parts, more Fructus Persicae 28 parts, Herba violae patrinii 15 parts, Radix Semiaquilegiae 28 parts, Mus are glued root 15 parts, white Rui core 13 parts, Herba adianti myriosori 29 parts, fly Lei Zi 11 part, kind stone 9 parts and five jiaos Cortex Acanthopanacis Radicis 15 parts.
The sterilization oral liquid of described treatment plain edition hand-foot-mouth disease, is made up of the raw material of following weight portion: golden Rhizoma et radix valerianae 10 parts, 20 parts, swallow clothing, black Wooden-fan 16 parts, more Fructus Persicae 12 parts, Herba violae patrinii 10 parts, Radix Semiaquilegiae 26 parts, Mus are glued root 11 parts, white Rui core 9 parts, Herba adianti myriosori 26 parts, fly Lei Zi 8 part, kind stone 6 parts and five jiaos Cortex Acanthopanacis Radicis 7 parts.
The sterilization oral liquid of described treatment plain edition hand-foot-mouth disease, is made up of the raw material of following weight portion: golden Rhizoma et radix valerianae 18 parts, 30 parts, swallow clothing, black Wooden-fan 21 parts, more Fructus Persicae 23 parts, Herba violae patrinii 18 parts, Radix Semiaquilegiae 31 parts, Mus are glued root 19 parts, white Rui core 15 parts, Herba adianti myriosori 35 parts, fly Lei Zi 14 part, kind stone 15 parts and five jiaos Cortex Acanthopanacis Radicis 19 parts.
The sterilization oral liquid of described treatment plain edition hand-foot-mouth disease, is made up of the raw material of following weight portion: golden Rhizoma et radix valerianae 12 parts, 23 parts, swallow clothing, black Wooden-fan 18 parts, more Fructus Persicae 14 parts, Herba violae patrinii 13 parts, Radix Semiaquilegiae 27 parts, Mus are glued root 13 parts, white Rui core 11 parts, Herba adianti myriosori 27 parts, fly Lei Zi 10 part, kind stone 8 parts and five jiaos Cortex Acanthopanacis Radicis 8 parts.
The sterilization oral liquid of described treatment plain edition hand-foot-mouth disease, is made up of the raw material of following weight portion: golden Rhizoma et radix valerianae 16 parts, 28 parts, swallow clothing, black Wooden-fan 20 parts, more Fructus Persicae 21 parts, Herba violae patrinii 17 parts, Radix Semiaquilegiae 30 parts, Mus are glued root 17 parts, white Rui core 14 parts, Herba adianti myriosori 32 parts, fly Lei Zi 12 part, kind stone 11 parts and five jiaos Cortex Acanthopanacis Radicis 17 parts.
Beneficial effect of the present invention is: the sterilization oral liquid for the treatment of plain edition hand-foot-mouth disease of the present invention is made up of following raw material: golden Rhizoma et radix valerianae, swallow clothing, black Wooden-fan, more Fructus Persicae, Herba violae patrinii, Radix Semiaquilegiae; Mus glues root, Bai Rui core, Herba adianti myriosori; Fly Lei Zi, kind stone, five jiaos of Cortex Acanthopanacis Radicis.
Gold Rhizoma et radix valerianae: bitter in the mouth, cold in nature.GUIXIN, lung, large intestine, urinary bladder channel.There is heat-clearing and toxic substances removing, removing heat from blood, detumescence, effect of dampness.
Swallow clothing: acrid in the mouth, hardship, cold nature.Return liver, stomach, large intestine channel.There is heat-clearing and toxic substances removing, effect of removing heat from blood.
Crow Wooden-fan: bitter in the mouth, cold in nature.Enter lung, Liver Channel.There is effect of heat-clearing and toxic substances removing.
More Fructus Persicae: bitter in the mouth, cold in nature, nontoxic.GUIXIN, liver, lung, stomach, tri-jiao channel.There is pathogenic fire purging relieving restlessness; Clearing away heat-damp and promoting diuresis; Effect of removing pathogenic heat from blood and toxic substance from the body.
Herba violae patrinii: bitter in the mouth, pungent, cold in nature, nontoxic GUIXIN, Liver Channel.There is effect of heat-clearing and toxic substances removing, removing heat from blood detumescence.
Radix Semiaquilegiae: sweet in the mouth, micro-acid, cool in nature.There is effect of heat-clearing and toxic substances removing, nourishing the lung to arrest cough, dissipating blood stasis for subsidence of swelling, promoting the production of body fluid to quench thirst.
Mus glues root: bitter in the mouth, cold in nature, nontoxic.Return lung meridian; Heart channel.There is heat of dispeling the wind, effect of detumescence poison.
Bai Rui core: sweet in the mouth; Cold in nature; Nontoxic.Return liver; The heart; Spleen; Lung meridian.There is wind and heat eliminating; Nourishing the liver to improve visual acuity; The effect of calming the nerves.
Herba adianti myriosori: bitter in the mouth; Sweet; Cold in nature.Return lung meridian; Liver Channel.There is dispelling wind and heat pathogens; Lung heat clearing; Effect of improving eyesight.
Fly Lei Zi: acrid in the mouth, hot in nature.Return lung meridian, spleen channel, stomach warp.Have cold expelling dampness, removing dampness disappears effect of painful abdominal mass, circulation of qi promoting warming middle-JIAO.
Kind stone: sweet in the mouth, light, cold in nature.Return bladder, lung, stomach warp.There is effect of heat clearing away removing dampness.
Five jiaos of Cortex Acanthopanacis Radicis: sweet in the mouth; Light; Cold nature.Be included into lung, stomach warp.There is effect of snobbish clearly water.
Fang Zhongjin Rhizoma et radix valerianae, swallow clothing, black Wooden-fan, more Fructus Persicae, Herba violae patrinii, the sub-heat-clearing and toxic substances removing of Radix Semiaquilegiae; Mus glues root, Bai Rui core, Herba adianti myriosori wind-dispelling heat-dissipating; Fly Lei Zi, kind stone, five jiaos of Cortex Acanthopanacis Radicis removing dampness expelling pathogenic factors from the exterior.Effective ingredient contained by above medicine has antiviral in various degree, antibacterial, antiinflammatory action and scavenging activated oxygen, antioxidation.
Hand-Food-Mouth Disease theory of Chinese medical science is diseases caused by exogenous pathogenic factor epidemic disease caused by damp-heat pathogen poison, when the heresy of epidemic disease poison injures lung, the heart, spleen, makes the extremity of the normal defensive QI spleen of lung and has one's ideas straightened out in the functional disorder of mouth, occurring above-mentioned Clinical symptoms, satisfies with our heat-clearing and toxic substances removing, removing dampness removing heat from blood for treatment.
1 data and method
The 96 routine infants that in May ,-2012 in April, 2010 is met the diagnostic criteria of hand-foot-mouth disease plain edition by 1.1 physical data are divided into matched group and treatment group at random.Matched group 48 example, man 25 example, female 23 example; 8 months ~ 6.7 years old age, average 2.7 years old; The course of disease is the shortest 1 day, the longest 4 days, average 2.7 days.Treatment group 48 example, man 24 example, female 24 example; 9 months ~ 6.8 years old age, average 2.6 years old; The course of disease is the shortest 1 day, the longest 3 days, average 2.6 days.2 groups of infants no significant difference (P > 0.05) in age, sex, the course of disease.
1.2 Therapeutic Method two groups are all brought down a fever, drink more water etc. suits the medicine to the illness, Supporting Therapy, and hemogram raises prompting bacteriological infection person and gives appropriate antibiotic therapy, and the obvious person of herpes of mouth gives BINGPENG SAN and blows deposited oral cavity.Matched group gives ribavirin pin 10 ~ 15mg/kg and adds 10% Glucose Liquid intravenous drip, 1 time/d.The oral liquid of the present invention that treatment group adopts is made up of following raw material: golden Rhizoma et radix valerianae, swallow clothing, black Wooden-fan, more Fructus Persicae, Herba violae patrinii, Radix Semiaquilegiae, Mus glue root, white Rui core, Herba adianti myriosori, fly Lei Zi, kind stone and five jiaos of Cortex Acanthopanacis Radicis forms.Consumption was decided according to the age, weight etc. of infant.Oral 2 times of every day, each 50ml.Two groups of equal 1 week of courses for the treatment of.
Observe fever time, herpes scab forming time, oral ulcer regression time.
1.3 observation index
Observe the fever time of two groups, herpes scab forming time, oral ulcer regression time.
2 results
2.1 criterions of therapeutical effect are cured: body temperature is normal, deflorescence, and oral ulcer heals.Effective: body temperature is normal, erythra reduces, and oral ulcer part reduces.Invalid: body temperature higher than normally, erythra and oral ulcer unchanged.
2.2 liang of group Clinical efficacy comparisons are in table 1.
Table 1 liang group Clinical efficacy comparison
| Group | Number of cases | Cure | Effectively | Invalid | Total effective rate |
| Matched group | 48 | 13 | 10 | 25 | 47.9％ |
| Treatment group | 48 | 40 | 8 | 0 | 100％ |
2.3 liang of group infants are brought down a fever, herpes incrustation, oral ulcer regression time compares in table 2.
A table 2 liang group infant is brought down a fever, herpes forms a scab, oral ulcer regression time compares
2.4 untoward reaction two groups all do not find obvious adverse reaction.
This observed result shows, and treatment group is at total effective rate and bring down a fever, herpes forms a scab, oral ulcer is all better than matched group in the time, and illustrate that oral liquid treatment plain edition hand-foot-mouth disease curative effect of the present invention is better, clinic is applied.
In sum, this oral liquid has the features such as the common hand-foot-mouth disease for the treatment of is rapid-action, effective, and safety range is large, and untoward reaction is few, and medication is convenient, low price, and clinic is promoted.
Detailed description of the invention
Below by embodiment, the present invention will be described in detail.
Embodiment 1
The sterilization oral liquid of described treatment plain edition hand-foot-mouth disease, is made up of the raw material of following weight portion: golden Rhizoma et radix valerianae 14 parts, 26 parts, swallow clothing, black Wooden-fan 19 parts, more Fructus Persicae 28 parts, Herba violae patrinii 15 parts, Radix Semiaquilegiae 28 parts, Mus are glued root 15 parts, white Rui core 13 parts, Herba adianti myriosori 29 parts, fly Lei Zi 11 part, kind stone 9 parts and five jiaos Cortex Acanthopanacis Radicis 15 parts.
Embodiment 2
The sterilization oral liquid of described treatment plain edition hand-foot-mouth disease, is made up of the raw material of following weight portion: golden Rhizoma et radix valerianae 10 parts, 20 parts, swallow clothing, black Wooden-fan 16 parts, more Fructus Persicae 12 parts, Herba violae patrinii 10 parts, Radix Semiaquilegiae 26 parts, Mus are glued root 11 parts, white Rui core 9 parts, Herba adianti myriosori 26 parts, fly Lei Zi 8 part, kind stone 6 parts and five jiaos Cortex Acanthopanacis Radicis 7 parts.
Embodiment 3
The sterilization oral liquid of described treatment plain edition hand-foot-mouth disease, is made up of the raw material of following weight portion: golden Rhizoma et radix valerianae 18 parts, 30 parts, swallow clothing, black Wooden-fan 21 parts, more Fructus Persicae 23 parts, Herba violae patrinii 18 parts, Radix Semiaquilegiae 31 parts, Mus are glued root 19 parts, white Rui core 15 parts, Herba adianti myriosori 35 parts, fly Lei Zi 14 part, kind stone 15 parts and five jiaos Cortex Acanthopanacis Radicis 19 parts.
Embodiment 4
The sterilization oral liquid of described treatment plain edition hand-foot-mouth disease, is made up of the raw material of following weight portion: golden Rhizoma et radix valerianae 12 parts, 23 parts, swallow clothing, black Wooden-fan 18 parts, more Fructus Persicae 14 parts, Herba violae patrinii 13 parts, Radix Semiaquilegiae 27 parts, Mus are glued root 13 parts, white Rui core 11 parts, Herba adianti myriosori 27 parts, fly Lei Zi 10 part, kind stone 8 parts and five jiaos Cortex Acanthopanacis Radicis 8 parts.
Embodiment 5
The sterilization oral liquid of described treatment plain edition hand-foot-mouth disease, is made up of the raw material of following weight portion: golden Rhizoma et radix valerianae 16 parts, 28 parts, swallow clothing, black Wooden-fan 20 parts, more Fructus Persicae 21 parts, Herba violae patrinii 17 parts, Radix Semiaquilegiae 30 parts, Mus are glued root 17 parts, white Rui core 14 parts, Herba adianti myriosori 32 parts, fly Lei Zi 12 part, kind stone 11 parts and five jiaos Cortex Acanthopanacis Radicis 17 parts.
Claims (8)
1. treat the sterilization oral liquid of plain edition hand-foot-mouth disease for one kind, it is characterized in that, be made up of following raw material: golden Rhizoma et radix valerianae, swallow clothing, black Wooden-fan, more Fructus Persicae, Herba violae patrinii, Radix Semiaquilegiae, Mus are glued root, white Rui core, Herba adianti myriosori, fly Lei Zi, kind stone and five jiaos of Cortex Acanthopanacis Radicis.
2. treat the sterilization oral liquid of plain edition hand-foot-mouth disease according to claim 1, it is characterized in that, be made up of the raw material of following weight portion: golden Rhizoma et radix valerianae 10-18 part, swallow clothing 20-30 part, black Wooden-fan 16-21 part, more Fructus Persicae 12-23 part, Herba violae patrinii 10-18 part, the sub-26-31 part of Radix Semiaquilegiae, Mus are glued root 11-19 part, white Rui core 9-15 part, Herba adianti myriosori 26-35 part, fly Lei Zi 8-14 part, kind stone 6-15 part and five jiaos of Cortex Acanthopanacis Radicis 7-19 parts.
3. treat the sterilization oral liquid of plain edition hand-foot-mouth disease according to claim 2, it is characterized in that, be made up of the raw material of following weight portion: golden Rhizoma et radix valerianae 12-16 part, swallow clothing 23-28 part, black Wooden-fan 18-20 part, more Fructus Persicae 14-21 part, Herba violae patrinii 13-17 part, the sub-27-30 part of Radix Semiaquilegiae, Mus are glued root 13-17 part, white Rui core 11-14 part, Herba adianti myriosori 27-32 part, fly Lei Zi 10-12 part, kind stone 8-11 part and five jiaos of Cortex Acanthopanacis Radicis 8-17 parts.
4. treat the sterilization oral liquid of plain edition hand-foot-mouth disease according to claim 3, it is characterized in that, be made up of the raw material of following weight portion: golden Rhizoma et radix valerianae 14 parts, 26 parts, swallow clothing, black Wooden-fan 19 parts, more Fructus Persicae 28 parts, Herba violae patrinii 15 parts, Radix Semiaquilegiae 28 parts, Mus are glued root 15 parts, white Rui core 13 parts, Herba adianti myriosori 29 parts, fly Lei Zi 11 part, kind stone 9 parts and five jiaos Cortex Acanthopanacis Radicis 15 parts.
5. treat the sterilization oral liquid of plain edition hand-foot-mouth disease according to claim 2, it is characterized in that, be made up of the raw material of following weight portion: golden Rhizoma et radix valerianae 10 parts, 20 parts, swallow clothing, black Wooden-fan 16 parts, more Fructus Persicae 12 parts, Herba violae patrinii 10 parts, Radix Semiaquilegiae 26 parts, Mus are glued root 11 parts, white Rui core 9 parts, Herba adianti myriosori 26 parts, fly Lei Zi 8 part, kind stone 6 parts and five jiaos Cortex Acanthopanacis Radicis 7 parts.
6. treat the sterilization oral liquid of plain edition hand-foot-mouth disease according to claim 2, it is characterized in that, be made up of the raw material of following weight portion: golden Rhizoma et radix valerianae 18 parts, 30 parts, swallow clothing, black Wooden-fan 21 parts, more Fructus Persicae 23 parts, Herba violae patrinii 18 parts, Radix Semiaquilegiae 31 parts, Mus are glued root 19 parts, white Rui core 15 parts, Herba adianti myriosori 35 parts, fly Lei Zi 14 part, kind stone 15 parts and five jiaos Cortex Acanthopanacis Radicis 19 parts.
7. treat the sterilization oral liquid of plain edition hand-foot-mouth disease according to claim 3, it is characterized in that, be made up of the raw material of following weight portion: golden Rhizoma et radix valerianae 12 parts, 23 parts, swallow clothing, black Wooden-fan 18 parts, more Fructus Persicae 14 parts, Herba violae patrinii 13 parts, Radix Semiaquilegiae 27 parts, Mus are glued root 13 parts, white Rui core 11 parts, Herba adianti myriosori 27 parts, fly Lei Zi 10 part, kind stone 8 parts and five jiaos Cortex Acanthopanacis Radicis 8 parts.
8. treat the sterilization oral liquid of plain edition hand-foot-mouth disease according to claim 3, it is characterized in that, be made up of the raw material of following weight portion: golden Rhizoma et radix valerianae 16 parts, 28 parts, swallow clothing, black Wooden-fan 20 parts, more Fructus Persicae 21 parts, Herba violae patrinii 17 parts, Radix Semiaquilegiae 30 parts, Mus are glued root 17 parts, white Rui core 14 parts, Herba adianti myriosori 32 parts, fly Lei Zi 12 part, kind stone 11 parts and five jiaos Cortex Acanthopanacis Radicis 17 parts.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510955068.XA CN105412767A (en) | 2015-12-17 | 2015-12-17 | Sterilization oral liquid for treating ordinary hand-foot-mouth disease |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103341066A (en) * | 2013-07-02 | 2013-10-09 | 石家庄市第五医院 | Chinese medicine oral liquid for treating hand-foot-mouth diseases of children and preparation method thereof |
| CN104116960A (en) * | 2014-08-03 | 2014-10-29 | 衣兰凯 | Traditional Chinese medicinal preparation for treating hand-foot-and-mouth disease |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103341066A (en) * | 2013-07-02 | 2013-10-09 | 石家庄市第五医院 | Chinese medicine oral liquid for treating hand-foot-mouth diseases of children and preparation method thereof |
| CN104116960A (en) * | 2014-08-03 | 2014-10-29 | 衣兰凯 | Traditional Chinese medicinal preparation for treating hand-foot-and-mouth disease |
Non-Patent Citations (1)
| Title |
|---|
| 刘素文，等: "清热解毒疏风祛湿法（抗毒合剂）治疗手足口病2期61例临床观察", 《第二十九次全国中医儿科学术大会暨"小儿瘩染性疾病曲中医药预防"培训班论文汇编》 * |
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