CN105412497A - Medicinal composition for treating pains in neck, shoulder and leg and preparation method of medicinal composition - Google Patents
Medicinal composition for treating pains in neck, shoulder and leg and preparation method of medicinal composition Download PDFInfo
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Abstract
The invention relates to a medicinal composition for treating pains in the neck, the shoulder and the leg and a preparation method of the medicinal composition. The medicinal composition is prepared from the following components in parts by weight: vines of Moghania fluminalis (Clarke ex prain) Li, Piper wallichii (Miq.) Hand.-Mazz.var. hupehense (DC.)Hand.-Mazz., Boehmeria clidemioides Miq.var. diffusa(Wedd.)Hand.-Mazz.[B.diffusa Wedd.], Asiatic toddalia root-bark, sambucus williamsii hance, Myrsine Africana L., Chinese fevervine herb and root, rhizome of Smilax China and attenuate St. Johnwort herb. The medicinal composition has the efficacy of treating pains in the neck, the shoulder and the leg, and through clinical observation, the medicinal composition is definite in curative effect and free of toxic and side effects.
Description
Technical field
The present invention relates to tcm field, be specifically related to a kind of pharmaceutical composition being used for the treatment of neck-shoulder pain, lumbago and leg pain and preparation method thereof.
Background technology
Neck-shoulder pain, lumbago and leg pain mostly be that chronic strain and aseptic inflammation cause with patient part pain, swelling even function limitation is one group of main disease.Commonly encountered diseases comprises: cervical spondylosis, scapulohumeral periarthritis, tenosynovitis, prolapse of lumbar intervertebral disc, lumbar muscle strain, hyperosteogeny diseases.Tractive, the torsion or bow for a long time being subject to the unexpected strike of external force, gravity compressing when soft tissue and exceeding soft tissue physiological range is bent over the desk, sitting, to bend over and sleeping posture is improper or use high pillow first-class for a long time, Portions of soft tissue is made to be in tractive state for a long time, be pulled in-house blood vessel be in for a long time half unobstructed and formed histanoxia state, all can cause neck, waist and leg pain symptom.Neck, waist and leg pain clinical signs is: rest pain, and pain has become a part for life; Activity is slightly many even bend over lost article found, sneeze time just fall ill, hurt like hell, function limitation; Overcast and rainy or wind-engaging is caught a cold and can be caused the recurrence of pain or increase the weight of.Neck, waist and leg pain has seriously upset daily life, the study and work of patient.
If at present for the drug main NSAID (non-steroidal anti-inflammatory drug) ibuprofen of neck, waist and leg pain, but can there is following side effect in ibuprofen: a few patients can occur that Nausea and vomiting, stomach burn feeling or slight dyspepsia, gastrointestinal ulceration and hemorrhage, transaminase's rising, headache, dizziness, tinnitus, blurred vision, psychentonia, drowsiness, lower limbs edema or body weight increase suddenly.Rare erythra, allergic nephritis, cystitis, nephrotic syndrome, necrosis of renal papillae or renal failure, bronchospasm.
Therefore, the medicine developing a kind of energy life-time service, safe and effective treatment neck-shoulder pain, lumbago and leg pain is needed.
Summary of the invention
The object of this invention is to provide a kind of pharmaceutical composition being used for the treatment of neck-shoulder pain, lumbago and leg pain.
The object of this invention is to provide a kind of preparation method being used for the treatment of the pharmaceutical composition of neck-shoulder pain, lumbago and leg pain.
The object of the invention is by following technical scheme realize:
The pharmaceutical composition being used for the treatment of neck-shoulder pain, lumbago and leg pain provided by the invention is made up of the composition of following weight portion:
Moghania fluminalis(C. B. Clarke) Li rattan 20-60 part, Caulis et Folium piperis 10-30 part, water numb 10-30 part alive, Sedum aizoon L. 8-20 part, Ramulus Sambuci Williamsii 8-20 part, stable pestle 8-20 part, Herba Paederiae 8-20 part, golden steel rattan 8-20 part, Herba hyperici attenuati 8-20 part.
Preferably, be prepared from by the composition containing following weight portion:
35 parts, Moghania fluminalis(C. B. Clarke) Li rattan, Caulis et Folium piperis 10 parts, water fiber crops 10 parts alive, Sedum aizoon L. 20 parts, Ramulus Sambuci Williamsii 15 parts, stable pestle 10 parts, Herba Paederiae 8 parts, 8 parts, golden steel rattan, Herba hyperici attenuati 8 parts.
Below crude drug source of the present invention:
Moghania fluminalis(C. B. Clarke) Li rattan: be the root of precipice, leguminous plant Guizhou bean rattan.The whole year can adopt.[nature and flavor] property is put down, and sweet in the mouth is micro-puckery.[function cures mainly] and blood, antipyretic.
Caulis et Folium piperis: be Piperaceae Piper plant Caulis et Folium piperis Piperwallichii (Miq.) Hand.-Mazz.var.hupehense (DC.) Hand.-Mazz., be used as medicine with stem, leaf or Herb.Herb can be adopted the whole year, dries.[nature and flavor] are pungent, temperature.[function cures mainly] dispelling wind and removing obstruction in the collateral, kidney invigorating and YANG supporting.Control anemofrigid-damp arthralgia, lumbago due to renal deficiency, sexual impotence, cough with asthma.
Water is lived fiber crops: be the herb of contrayerva Herba Catharanthi longifolii BoehmeriaclidemioidesMiq.var.diffusa (Wedd.) Hand.-Mazz. [B.diffusaWedd.], autumn gathers, using fresh herb or dry.[nature and flavor] are pungent, temperature.[function cures mainly] expelling wind and removing dampness, main air pain of dampness syndrome.
Sedum aizoon L.: be the herb of Violaceae plant Viola arcuata.Autumn gathers.Clean and dry.[nature and flavor] pungent fiber crops, temperature.[function cures mainly] promoting the flow of QI in the collateral by warming the meridian, stopping bleeding and knitting the fractured bone.Open fracture is controlled in external.
Ramulus Sambuci Williamsii: be the stem branch of caprifoliaceae plant Ramulus Sambuci Williamsii.The whole year can adopt.[nature and flavor] sweetness and bitterness, flat.[function cures mainly] dispels the wind, and dampness removing is invigorated blood circulation, pain relieving.Dispelling the wind and dampness pathogens bones and muscles pain, lumbago, edema, pruritus due to wind pathogen, urticaria, puerperal blood faints, treating swelling and pain by traumatic injury, fracture, wound hemorrhage.
Stable pestle: the young Myrsineafricana. of Myrsinacea pellet in a shotgun cartridge platymiscium ferrum, is used as medicine with root, Herb or leaf.The picking leaves of autumn in summer, using fresh herb or dry; Root or Herb, the four seasons can adopt, and clean section is dried.[nature and flavor] are bitter, puckery, micro-sweet, flat.[function cures mainly] clearing away heat-damp and promoting diuresis, astringing to arrest bleeding.Root or Herb: enteritis, dysentery, metrorrhagia, has blood in stool, hemoptysis of pulmonary tuberculosis, toothache.Burn and scald is controlled in leaf external.Herb: invigorate blood circulation, dispels the wind, and reason is wet.Dispelling the wind and dampness pathogens arthralgia pain, has loose bowels, dysentery, stranguria with blood, impairment caused by overstrain hemoptysis.
Herba Paederiae: be the herb of Maguireothamnus speciosus fevervine, herb of gathering summer, dries.[nature and flavor] sweet, micro-hardship, property is put down.[function cures mainly] expelling wind and removing dampness, analgesic antidotal, promoting digestion and removing stagnation, effect of promoting blood circulation and detumescence.For bones and muscles pain due to rheumatism, traumatic injury, traumatic pain, liver and gall and gastrointestinal angor, dyspepsia, infantile malnutrition, bronchitis; Outer for dermatitis, eczema and sore swollen toxin.
Gold steel rattan: be the rhizome of liliaceous plant southwest Rhizoma Smilacis Chinensis.[nature and flavor] temperature, taste is micro-pungent.[function cures mainly] dispels the wind, and invigorates blood circulation, effect of removing toxic substances.Dispelling the wind and dampness pathogens lumbago and skelalgia, traumatic injury, scrofula.
Herba hyperici attenuati: the wild Radix Hyperici Monogyni (Herba Hyperici Monogyni) HypericumattenuatumChoisy. of Hypericaceae hypericum, with all herbal medicine.Autumn gathers, and dries.[nature and flavor] are bitter, flat.[function cures mainly] stops blooding, analgesia, lactogenesis.For spitting of blood, spit blood, metrorrhagia, rheumatic arthritis, neuralgia, traumatic injury, agalactosis, mastitis; Wound hemorrhage is controlled in external, carbuncle furuncle and phyma poison.
Another aspect of the present invention there is provided the preparation method of pharmaceutical composition of the present invention, and this Chinese medicine composition is prepared from by following methods:
Get Moghania fluminalis(C. B. Clarke) Li rattan, Caulis et Folium piperis, water fiber crops alive, Sedum aizoon L., Ramulus Sambuci Williamsii, stable pestle, Herba Paederiae, Jin Gangteng, Herba hyperici attenuati, extracting in water 1-3 time, each amount of water is equivalent to the 4-8 of medical material gross weight doubly, each extraction time is 1-3 hour, merge extractive liquid, filter, when filtrate is concentrated into 60-80 DEG C, relative density is the clear paste of 1.05-1.20, to obtain final product.
Preferably, be prepared from by following methods:
Get Moghania fluminalis(C. B. Clarke) Li rattan, Caulis et Folium piperis, water fiber crops alive, Sedum aizoon L., Ramulus Sambuci Williamsii, stable pestle, Herba Paederiae, Jin Gangteng, Herba hyperici attenuati, extracting in water 1 time, amount of water is equivalent to 8 times of medical material gross weight, 1 extraction time was 3 hours, merge extractive liquid, filter, when filtrate is concentrated into 60 DEG C, relative density is the clear paste of 1.05-1.20, to obtain final product.
The pharmaceutical composition for the treatment of neck-shoulder pain, lumbago and leg pain of the present invention, with pharmaceutically acceptable carrier combination, can make various common dosage forms, as oral liquid, granule, tablet, capsule, pill, varnish, emplastrum etc.
Pharmaceutically acceptable carrier of the present invention includes but not limited to following:
Diluent: starch, Icing Sugar, lactose, dextrin, microcrystalline Cellulose, inorganic salt, sugar alcohols etc.
Wetting agent and binding agent: purified water, ethanol, gelatin, Polyethylene Glycol, cellulose derivative etc.
Disintegrating agent: starch, carboxymethyl starch sodium, cellulose derivative, polyvinylpolypyrrolidone etc.
Lubricant: magnesium stearate, micropowder silica gel, Pulvis Talci, Polyethylene Glycol etc.
Cosolvent: water, ethanol, glycerol, propylene glycol, liquid Paraffin, plant wet goods.
Correctives: sucrose, monosaccharide, aromatic etc.
Antiseptic: benzoic acid, sorbic acid, methyl ester, ethyl ester, propyl ester etc.
Method 1: tablet
Get above made pharmaceutical composition clear paste of the present invention, be dried to dried cream powder, add tablet and commonly use adjuvant, production method is prepared into Tablets routinely.
Above-mentioned tablet is commonly used adjuvant and is comprised one of diluent, wetting agent, binding agent, disintegrating agent, lubricant or whole.
Method 2: granule
Get above made pharmaceutical composition clear paste of the present invention, be dried to dried cream powder, add granule and commonly use adjuvant, production method is prepared into granule of the present invention routinely.
Above-mentioned granule is commonly used adjuvant and is comprised one of diluent, wetting agent, binding agent, disintegrating agent or whole.
Method 3: capsule
Get above made pharmaceutical composition clear paste of the present invention, be dried to dried cream powder, add capsule and commonly use adjuvant, production method is prepared into capsule of the present invention routinely.
Above-mentioned capsule is commonly used adjuvant and is comprised one of diluent, wetting agent, binding agent, disintegrating agent, lubricant or whole.
Method 4: oral liquid
Get above made pharmaceutical composition clear paste of the present invention, add oral liquid and commonly use adjuvant, production method is prepared into oral liquid of the present invention routinely.
Above-mentioned syrup is commonly used adjuvant and is comprised one of correctives, antiseptic, cosolvent or whole.
Method 5: emplastrum
Get above made pharmaceutical composition clear paste of the present invention, add emplastrum and commonly use adjuvant, production method is prepared into emplastrum of the present invention routinely.
Fang Xie:
Neck-shoulder pain, lumbago and leg pain is the general name of many diseases, and the traditional Chinese medical science is referred to as arthromyodynia, and the traditional Chinese medical science thinks that morbidity endogenous cause of ill mostly is insufficiency of vital energy and blood or becomes estranged, and exopathogenic factor mostly then is wind-cold damp pathogen invasion skin, multiple abscess meridians, and healthy energy is hindered can not declare row by evil.The rule for the treatment of is many starts with from promoting flow of QI and blood, expelling wind and cold, promoting the flow of QI in the collateral by warming the meridian.In side Moghania fluminalis(C. B. Clarke) Li rattan property put down, sweet in the mouth is micro-puckery, can and blood, antipyretic is monarch drug; Caulis et Folium piperis, water live fiber crops, Sedum aizoon L. three property is pungent, temperature, can dispelling wind and removing obstruction in the collateral, Bu Shen Zhuang expelling wind and removing dampness, promoting the flow of QI in the collateral by warming the meridian is ministerial drug; Ramulus Sambuci Williamsii, stable pestle, Herba Paederiae sweetness and bitterness, flat, can dispel the wind, dampness removing, heat clearing away, analgesic antidotal are adjuvant drug, be aided with Jin Gangteng again, Herba hyperici attenuati dispels the wind, invigorate blood circulation, hemostasis, analgesia is for making medicine, in side, all medicines share and can play dispelling cold and removing dampness, dredging the meridian, a surname's venting QI-blood, reducing swelling and alleviating pain, remove muscle spasm, the effect of loosen adhesion, easing joint movement.
A kind of pharmaceutical composition being used for the treatment of neck-shoulder pain, lumbago and leg pain provided by the invention has the following advantages:
1, the total therapeutic effect of clinical observation compares display, and treatment group total effective rate is 93.0%, and matched group total effective rate is 81.0%, and the present invention is evident in efficacy is better than matched group curative effect.
2, pharmaceutical composition of the present invention can oral or external application, and when herb medicinal paste for external application amount is the 0.5-1.5 times of oral dose, effect is better.
3, do not find untoward reaction in clinical trial, safety detection, efficacy test do not find and test relevant new abnormal case.
Detailed description of the invention
Following examples for illustration of the present invention, but are not used for limiting the scope of the invention.
embodiment 1:
Get Moghania fluminalis(C. B. Clarke) Li rattan 35g, Caulis et Folium piperis 10g, water lives numb 10g, Sedum aizoon L. 20g, Ramulus Sambuci Williamsii 15g, stable pestle 10g, Herba Paederiae 8g, golden steel rattan 8g, Herba hyperici attenuati 8g.Extracting in water 1 time, amount of water is equivalent to 8 times of medical material gross weight, extraction time is 3 hours, merge extractive liquid, filters, when filtrate is concentrated into 60-80 DEG C, relative density is the clear paste of 1.05-1.20, and vacuum drying becomes dried cream powder, pulverize 120 mesh sieves, add appropriate starch, microcrystalline Cellulose, gelatin, carboxymethyl starch sodium, magnesium stearate, micropowder silica gel, sucrose, mix homogeneously, soft material processed, granulation, tabletted and get final product.
embodiment 2:
Get Moghania fluminalis(C. B. Clarke) Li rattan 45g, Caulis et Folium piperis 25g, water lives numb 25g, Sedum aizoon L. 25g, Ramulus Sambuci Williamsii 15g, stable pestle 15g, Herba Paederiae 15g, golden steel rattan 15g, Herba hyperici attenuati 15g.Extracting in water 2 times, each amount of water is equivalent to 6 times of medical material gross weight, and each extraction time is 2 hours, merge extractive liquid, filter, when filtrate is concentrated into 60-80 DEG C, relative density is the clear paste of 1.05-1.20, and vacuum drying becomes dried cream powder, pulverizes 120 mesh sieves, add appropriate starch, sucrose, mix homogeneously, soft material processed, granulation, granulate, obtain granule.
embodiment 3:
Get Moghania fluminalis(C. B. Clarke) Li rattan 20g, Caulis et Folium piperis 10g, water lives numb 10g, Sedum aizoon L. 8g, Ramulus Sambuci Williamsii 8g, stable pestle 8g, Herba Paederiae 8g, golden steel rattan 8g, Herba hyperici attenuati 8g.Extracting in water 3 times, each amount of water is equivalent to 4 times of medical material gross weight, and each extraction time is 1 hour, merge extractive liquid, filter, when filtrate is concentrated into 60-80 DEG C, relative density is the clear paste of 1.05-1.20, and vacuum drying becomes dried cream powder, pulverized 120 mesh sieves, add appropriate starch, mix homogeneously, soft material processed, granulation, granulate, fill, obtain capsule.
embodiment 4:
Get Moghania fluminalis(C. B. Clarke) Li rattan 60g, Caulis et Folium piperis 30g, water lives numb 30g, Sedum aizoon L. 20g, Ramulus Sambuci Williamsii 20g, stable pestle 20g, Herba Paederiae 20g, golden steel rattan 20g, Herba hyperici attenuati 20g.Extracting in water 3 times, each amount of water is equivalent to 4 times of medical material gross weight, and each extraction time is 1 hour, merge extractive liquid, filters, and when filtrate is concentrated into 60-80 DEG C, relative density is the clear paste of 1.05-1.20, add appropriate purified water, filtration, fill, obtain oral liquid.
embodiment 5:
Get Moghania fluminalis(C. B. Clarke) Li rattan 60g, Caulis et Folium piperis 25g, water lives numb 25g, Sedum aizoon L. 20g, Ramulus Sambuci Williamsii 15g, stable pestle 15g, Herba Paederiae 15g, golden steel rattan 20g, Herba hyperici attenuati 20g.Extracting in water 3 times, each amount of water is equivalent to 4 times of medical material gross weight, and each extraction time is 1 hour, merge extractive liquid, filters, and when filtrate is concentrated into 60-80 DEG C, relative density is the clear paste of 1.05-1.20, by clear paste coating with macromolecular material, obtained emplastrum.
clinical trial
One, physical data
Choose make a definite diagnosis neck-shoulder pain, lumbago and leg pain patient totally 100 example, the course of disease 6 months to 25 years, 18 years old ~ 70 years old age, average 50 years old.Clinical manifestation is neck, shoulder arm and/or waist leg pain, creeping chill, pain and numbness.At random 100 routine patients are divided into matched group and each 50 examples for the treatment of group.
Two, case selection standard
1, there are neck, shoulder arm and/or waist leg pain, acid swollen, creeping chill, pain and numbness, meet the dependent diagnostic standard person in " modern neck-shoulder pain, lumbago and leg pain Clinics and Practices ".
2,18 years old ~ 70 years old age.
3, get rid of have that hepatic and renal function is abnormal, more serious cardiovascular and cerebrovascular disease and other nervous system disease and just drug administration person.
Three, neck-shoulder pain, lumbago and leg pain curative effect determinate standard
Cure: pain, acid is swollen etc., and symptom disappears completely, functional activity recovers normal;
Effective: the symptoms such as pain disappear substantially, functional activity recovers normal substantially;
Take a turn for the better: pain relief, functional activity improves;
Invalid: treatment front and back pain, functional activity obstacle are unchanged.
Four, test method
1, medication is tested
Treatment group: the embodiment of the present invention 1,3 pieces/times, 3 times/day.
Matched group: Radix Angelicae Pubescentis et Herba Taxilli Decoction (Radix Angelicae Pubescentis 9g, Herba Taxilli, the Cortex Eucommiae, Radix Achyranthis Bidentatae, Herba Asari, Radix Gentianae Macrophyllae, Poria, Cortex Cinnamomi heart Radix Saposhnikoviae, Rhizoma Chuanxiong, Radix Ginseng, Radix Glycyrrhizae, Radix Angelicae Sinensis, Radix Paeoniae, each 6g of Radix Rehmanniae), every day 1 dose.
3, the course for the treatment of: 7 days be a course for the treatment of, a course for the treatment of is taken
4, follow up a case by regular visits to: recovery from illness case was followed up a case by regular visits to after three months.
Five, result
(1) observation of curative effect
1, neck-shoulder pain, lumbago and leg pain total effects situation, in table 1.
A table 1 liang group patient total effects compares
Note: compare with matched group, * P<0.01.
Table 1 result shows, and the comparitive study for the treatment of group and treatment of control group neck-shoulder pain, lumbago and leg pain has significant difference (P<0.01), and the curative effect of result prompting treatment group is apparently higher than matched group, and namely the neck-shoulder pain, lumbago and leg pain curative effect for the treatment of group is better than matched group.
Six, discuss
1, comparative result between each disease kind:
Total therapeutic effect compares, and treatment group total effective rate is respectively 93.0%; Matched group total effective rate is 81.0%.Always there is significant differences effective in cure comparison for treatment group and matched group, and treatment group total effective rate is higher than matched group.
2, do not find untoward reaction in clinical trial, safety detection, efficacy test do not find and test relevant new abnormal case.
Seven, conclusion
The present invention is Chinese medicine preparation, has dispelling cold and removing dampness, dredging the meridian, a surname's venting QI-blood, reducing swelling and alleviating pain, removes muscle spasm, effect of loosen adhesion, easing joint movement, be applicable to treat cervical spondylosis, scapulohumeral periarthritis, tenosynovitis, prolapse of lumbar intervertebral disc, lumbar muscle strain, the neck-shoulder pain, lumbago and leg pain diseases such as hyperosteogeny, through clinical observation determined curative effect, non-invention toxicity is a kind of new Chinese medicine be worthy to be popularized.And preparation method of the present invention compared with prior art, curative effect has significant difference.
Although above with general explanation, detailed description of the invention and test, the present invention is described in detail, and on basis of the present invention, can make some modifications or improvements it, this will be apparent to those skilled in the art.Therefore, these modifications or improvements without departing from theon the basis of the spirit of the present invention, all belong to the scope of protection of present invention.
Claims (6)
1. be used for the treatment of a pharmaceutical composition for neck-shoulder pain, lumbago and leg pain, it is characterized in that it is made up of the composition of following weight portion: Moghania fluminalis(C. B. Clarke) Li rattan 20-60 part, Caulis et Folium piperis 10-30 part, water numb 10-30 part alive, Sedum aizoon L. 8-20 part, Ramulus Sambuci Williamsii 8-20 part, stable pestle 8-20 part, Herba Paederiae 8-20 part, golden steel rattan 8-20 part, Herba hyperici attenuati 8-20 part.
2. the pharmaceutical composition for the treatment of neck-shoulder pain, lumbago and leg pain as claimed in claim 1, is characterized in that it is made up of the composition of following weight portion: 35 parts, Moghania fluminalis(C. B. Clarke) Li rattan, Caulis et Folium piperis 10 parts, water fiber crops 10 parts alive, Sedum aizoon L. 20 parts, Ramulus Sambuci Williamsii 15 parts, stable pestle 10 parts, Herba Paederiae 8 parts, 8 parts, golden steel rattan, Herba hyperici attenuati 8 parts.
3. the pharmaceutical composition for the treatment of neck-shoulder pain, lumbago and leg pain as claimed in claim 1 or 2, is characterized in that Moghania fluminalis(C. B. Clarke) Li rattan, Caulis et Folium piperis, water lives fiber crops, the active component employing water extraction of Sedum aizoon L., Ramulus Sambuci Williamsii, stable pestle, Herba Paederiae, Jin Gangteng, Herba hyperici attenuati is prepared from.
4. the pharmaceutical composition for the treatment of neck-shoulder pain, lumbago and leg pain as claimed in claim 3, it is characterized in that Moghania fluminalis(C. B. Clarke) Li rattan, Caulis et Folium piperis, water is lived numb, Sedum aizoon L., Ramulus Sambuci Williamsii, stable pestle, Herba Paederiae, gold steel rattan, the active component of Herba hyperici attenuati is prepared from by the following method: get Moghania fluminalis(C. B. Clarke) Li rattan, Caulis et Folium piperis, water is lived numb, Sedum aizoon L., Ramulus Sambuci Williamsii, stable pestle, Herba Paederiae, gold steel rattan, Herba hyperici attenuati, extracting in water 1-3 time, each amount of water is equivalent to the 4-8 of medical material gross weight doubly, each extraction time is 1-3 hour, merge extractive liquid, filter, when filtrate is concentrated into 60-80 DEG C, relative density is the clear paste of 1.05-1.20, obtain.
5. the pharmaceutical composition for the treatment of neck-shoulder pain, lumbago and leg pain as claimed in claim 3, it is characterized in that Moghania fluminalis(C. B. Clarke) Li rattan, Caulis et Folium piperis, water is lived numb, Sedum aizoon L., Ramulus Sambuci Williamsii, stable pestle, Herba Paederiae, gold steel rattan, the active component of Herba hyperici attenuati is prepared from by the following method: get Moghania fluminalis(C. B. Clarke) Li rattan, Caulis et Folium piperis, water is lived numb, Sedum aizoon L., Ramulus Sambuci Williamsii, stable pestle, Herba Paederiae, gold steel rattan, Herba hyperici attenuati, extracting in water 1 time, amount of water is equivalent to 8 times of medical material gross weight, 1 extraction time was 3 hours, merge extractive liquid, filter, when filtrate is concentrated into 60 DEG C, relative density is the clear paste of 1.05-1.20, obtain.
6. be used for the treatment of a pharmaceutical preparation for neck-shoulder pain, lumbago and leg pain, prepared by acceptable carrier on the pharmaceutical composition of the treatment neck-shoulder pain, lumbago and leg pain described in claim 1 or 2 and pharmaceuticals industry and form.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
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Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104258097A (en) * | 2014-10-28 | 2015-01-07 | 合肥丰瑞隆生物科技有限公司 | Anti-inflammatory and analgesic balm |
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104258097A (en) * | 2014-10-28 | 2015-01-07 | 合肥丰瑞隆生物科技有限公司 | Anti-inflammatory and analgesic balm |
Non-Patent Citations (1)
| Title |
|---|
| 郭孔杰等: "《中医临证集锦》", 31 January 2014, 兰州大学出版社 * |
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Application publication date: 20160323 |