CN105407906A - 预防或治疗巴斯综合征的方法和组合物 - Google Patents
预防或治疗巴斯综合征的方法和组合物 Download PDFInfo
- Publication number
- CN105407906A CN105407906A CN201480022767.2A CN201480022767A CN105407906A CN 105407906 A CN105407906 A CN 105407906A CN 201480022767 A CN201480022767 A CN 201480022767A CN 105407906 A CN105407906 A CN 105407906A
- Authority
- CN
- China
- Prior art keywords
- peptide
- taz1
- arg
- phe
- lys
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/06—Tripeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/07—Tetrapeptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Immunology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Neurology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pulmonology (AREA)
- Hospice & Palliative Care (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202211635437.3A CN115990242A (zh) | 2013-03-01 | 2014-02-28 | 预防或治疗巴斯综合征的方法和组合物 |
| CN202211634590.4A CN115990241A (zh) | 2013-03-01 | 2014-02-28 | 预防或治疗巴斯综合征的方法和组合物 |
Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361771534P | 2013-03-01 | 2013-03-01 | |
| US201361771642P | 2013-03-01 | 2013-03-01 | |
| US61/771,534 | 2013-03-01 | ||
| US61/771,642 | 2013-03-01 | ||
| US201361839753P | 2013-06-26 | 2013-06-26 | |
| US61/839,753 | 2013-06-26 | ||
| PCT/US2014/019622 WO2014134554A1 (en) | 2013-03-01 | 2014-02-28 | Methods and compositions for the prevention or treatment of barth syndrome |
Related Child Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202211634590.4A Division CN115990241A (zh) | 2013-03-01 | 2014-02-28 | 预防或治疗巴斯综合征的方法和组合物 |
| CN202211635437.3A Division CN115990242A (zh) | 2013-03-01 | 2014-02-28 | 预防或治疗巴斯综合征的方法和组合物 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105407906A true CN105407906A (zh) | 2016-03-16 |
Family
ID=51428869
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202211635437.3A Pending CN115990242A (zh) | 2013-03-01 | 2014-02-28 | 预防或治疗巴斯综合征的方法和组合物 |
| CN201480022767.2A Pending CN105407906A (zh) | 2013-03-01 | 2014-02-28 | 预防或治疗巴斯综合征的方法和组合物 |
| CN202211634590.4A Pending CN115990241A (zh) | 2013-03-01 | 2014-02-28 | 预防或治疗巴斯综合征的方法和组合物 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202211635437.3A Pending CN115990242A (zh) | 2013-03-01 | 2014-02-28 | 预防或治疗巴斯综合征的方法和组合物 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202211634590.4A Pending CN115990241A (zh) | 2013-03-01 | 2014-02-28 | 预防或治疗巴斯综合征的方法和组合物 |
Country Status (9)
| Country | Link |
|---|---|
| US (5) | US9687519B2 (enExample) |
| EP (2) | EP2961420B1 (enExample) |
| JP (4) | JP6518197B2 (enExample) |
| CN (3) | CN115990242A (enExample) |
| CA (1) | CA2916880C (enExample) |
| DK (1) | DK2961420T3 (enExample) |
| ES (1) | ES2750258T3 (enExample) |
| HU (1) | HUE046924T2 (enExample) |
| WO (1) | WO2014134554A1 (enExample) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107312066A (zh) * | 2011-12-09 | 2017-11-03 | 康德生物医疗技术公司 | 芳香族阳离子肽及其用途 |
| CN115990242A (zh) | 2013-03-01 | 2023-04-21 | 康德生物医疗有限公司 | 预防或治疗巴斯综合征的方法和组合物 |
| CN110339339A (zh) | 2013-03-01 | 2019-10-18 | 康德生物医疗技术公司 | 治疗线粒体疾病的方法 |
| CA2916977A1 (en) | 2013-06-26 | 2014-12-31 | Stealth Biotherapeutics Corp | Methods and compositions for detecting and diagnosing diseases and conditions |
| US9550981B2 (en) | 2014-01-22 | 2017-01-24 | University Of Washington | Modified tafazzin proteins and methods of making and using the same |
| WO2016094791A1 (en) * | 2014-12-12 | 2016-06-16 | University Of Washington | Methods for treating and preventing cardiomyopathy |
| WO2018104172A1 (en) | 2016-12-06 | 2018-06-14 | Centre National De La Recherche Scientifique (Cnrs) | Compounds for treating barth syndrome |
| WO2018187400A1 (en) | 2017-04-05 | 2018-10-11 | Stealth Biotherapeutics Corp. | Crystalline salt forms of boc-d-arg-dmt-lys-(boc)-phe-nh2 |
| US10676506B2 (en) | 2018-01-26 | 2020-06-09 | Stealth Biotherapeutics Corp. | Crystalline bis- and tris-hydrochloride salt of elamipretide |
| EP3898653A4 (en) * | 2018-12-18 | 2022-08-24 | Stealth BioTherapeutics Inc. | ANALOGS TARGETING MITOCHONDRIAL DISEASES |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012129427A2 (en) * | 2011-03-24 | 2012-09-27 | Cornell University | Aromatic-cationic peptides and uses of same |
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| US5858784A (en) | 1991-12-17 | 1999-01-12 | The Regents Of The University Of California | Expression of cloned genes in the lung by aerosol- and liposome-based delivery |
| US5716644A (en) | 1992-06-11 | 1998-02-10 | Alkermes, Inc. | Composition for sustained release of non-aggregated erythropoietin |
| US5674534A (en) | 1992-06-11 | 1997-10-07 | Alkermes, Inc. | Composition for sustained release of non-aggregated erythropoietin |
| US5989463A (en) | 1997-09-24 | 1999-11-23 | Alkermes Controlled Therapeutics, Inc. | Methods for fabricating polymer-based controlled release devices |
| US6245740B1 (en) | 1998-12-23 | 2001-06-12 | Amgen Inc. | Polyol:oil suspensions for the sustained release of proteins |
| AU2002365425A1 (en) | 2001-08-06 | 2003-09-02 | Vanderbilt University | An apparatus and methods for using biological material to discriminate an agent |
| BRPI0105509B8 (pt) | 2001-11-05 | 2021-05-25 | Univ Minas Gerais | formulações do peptídeo angiotensina-(1-7) usando as ciclodextrinas, lipossomas e o polímero plga |
| SI2656854T1 (sl) | 2003-02-04 | 2015-09-30 | Cornell Research Foundation, Inc. | Uporabe aromatsko-kationskega peptida |
| CN101440124B (zh) | 2003-02-04 | 2012-07-18 | 科内尔研究基金会 | 用于防止线粒体通透性改变的方法 |
| AU2004210013A1 (en) * | 2003-02-10 | 2004-08-19 | Autogen Research Pty Ltd | Therapeutic molecules |
| WO2005023274A1 (en) | 2003-09-05 | 2005-03-17 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Treatment and prevention of inflammatory disease and mitochondrial dysfunction with high dose selenium |
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| AU2007237899A1 (en) * | 2006-04-18 | 2007-10-25 | Cortendo Invest, Ab | Methods and compositions for treating barth syndrome, cardiomyopathy, mitochondrial diseases and other conditions |
| CA2688125A1 (en) | 2007-05-02 | 2008-11-13 | The Mclean Hospital Corporation | Methods and compositions for mitochondrial replacement therapy |
| US20080318909A1 (en) * | 2007-06-14 | 2008-12-25 | Sparagna Genevieve C | Use Of Linoleic Compounds Against Heart Failure |
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| CN107802821A (zh) * | 2008-02-26 | 2018-03-16 | 康奈尔大学 | 用于防止和治疗急性肾损伤的方法 |
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| EP3563862B1 (en) | 2009-03-20 | 2021-05-05 | The General Hospital Corporation d/b/a Massachusetts General Hospital | D-arg-2'6'-dimethyltyrosine-lys-phe-nh2 for use in the prevention of secondary complications of burn injuries |
| EP2419513A2 (en) | 2009-04-17 | 2012-02-22 | The Salk Institute For Biological Studies | Regulation of aging by modulation of mitochondrial function |
| US20120046363A1 (en) | 2009-05-11 | 2012-02-23 | University Of Maryland, Baltimore | Docosahexaenoic acid for the treatment of heart failure |
| CN105031605A (zh) | 2009-08-12 | 2015-11-11 | 康奈尔大学 | 预防或治疗代谢综合症的方法 |
| SMT202300433T1 (it) * | 2009-08-24 | 2024-01-10 | Stealth Biotherapeutics Inc | Peptide per l'uso nella prevenzione o nel trattamento della degenerazione maculare |
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| HK1204988A1 (en) | 2012-02-22 | 2015-12-11 | Stealth Peptides International, Inc. | Methods and compositions for preventing or treating ophthalmic conditions |
| CN104203262A (zh) * | 2012-02-23 | 2014-12-10 | 康奈尔大学 | 芳香族阳离子肽及其用途 |
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| WO2014066419A2 (en) * | 2012-10-22 | 2014-05-01 | Stealth Peptides International, Inc. | Methods for reducing risks associated with heart failure and factors associated therewith |
| CN110339339A (zh) | 2013-03-01 | 2019-10-18 | 康德生物医疗技术公司 | 治疗线粒体疾病的方法 |
| CN115990242A (zh) * | 2013-03-01 | 2023-04-21 | 康德生物医疗有限公司 | 预防或治疗巴斯综合征的方法和组合物 |
| CA2916977A1 (en) * | 2013-06-26 | 2014-12-31 | Stealth Biotherapeutics Corp | Methods and compositions for detecting and diagnosing diseases and conditions |
-
2014
- 2014-02-28 CN CN202211635437.3A patent/CN115990242A/zh active Pending
- 2014-02-28 EP EP14756991.7A patent/EP2961420B1/en active Active
- 2014-02-28 CA CA2916880A patent/CA2916880C/en active Active
- 2014-02-28 JP JP2015560377A patent/JP6518197B2/ja active Active
- 2014-02-28 DK DK14756991.7T patent/DK2961420T3/da active
- 2014-02-28 ES ES14756991T patent/ES2750258T3/es active Active
- 2014-02-28 CN CN201480022767.2A patent/CN105407906A/zh active Pending
- 2014-02-28 EP EP19190165.1A patent/EP3626252A1/en not_active Withdrawn
- 2014-02-28 HU HUE14756991A patent/HUE046924T2/hu unknown
- 2014-02-28 WO PCT/US2014/019622 patent/WO2014134554A1/en not_active Ceased
- 2014-02-28 CN CN202211634590.4A patent/CN115990241A/zh active Pending
- 2014-02-28 US US14/771,408 patent/US9687519B2/en active Active
-
2017
- 2017-06-19 US US15/626,255 patent/US11083771B2/en active Active
-
2019
- 2019-04-19 JP JP2019080101A patent/JP6918046B2/ja active Active
-
2020
- 2020-07-15 US US16/929,370 patent/US11083772B2/en active Active
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2021
- 2021-02-10 JP JP2021019903A patent/JP7072692B2/ja active Active
- 2021-07-09 US US17/371,475 patent/US11771734B2/en active Active
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2022
- 2022-05-10 JP JP2022077425A patent/JP7381652B2/ja active Active
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2023
- 2023-08-23 US US18/454,319 patent/US12268724B2/en active Active
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012129427A2 (en) * | 2011-03-24 | 2012-09-27 | Cornell University | Aromatic-cationic peptides and uses of same |
Non-Patent Citations (4)
| Title |
|---|
| DITI RONVELIA: "Intrafamilial variability for novel TAZ gene mutation: Barth syndrome with dilated cardiomyopathy and heart failure in an infant and left ventricular noncompaction in his great-uncle", 《MOLECULAR GENETICS AND METABOLISM》 * |
| KATRIN BRANDNER: "Taz1, an Outer Mitochondrial Membrane Protein, Affects Stability and Assembly of Inner Membrane Protein Complexes: Implications for Barth Syndrome", 《MOLECULAR BIOLOGY OF THE CELL》 * |
| PHOON CK: "Tafazzin Knockdown in Mice Leads to a Developmental Cardiomyopathy With Early Diastolic Dysfunction Preceding Myocardial Noncompaction", 《JOURNAL OF AMERICAN HEART ASSOCIATION》 * |
| 邹佳: "新型抗氧化肽SS31体外辐射防护作用及其机制的初步研究", 《辐射研究与辐射工艺学报》 * |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2014134554A1 (en) | 2014-09-04 |
| JP6918046B2 (ja) | 2021-08-11 |
| CA2916880C (en) | 2021-02-09 |
| US9687519B2 (en) | 2017-06-27 |
| US11083771B2 (en) | 2021-08-10 |
| EP2961420B1 (en) | 2019-09-11 |
| JP2016511259A (ja) | 2016-04-14 |
| ES2750258T3 (es) | 2020-03-25 |
| JP2019147815A (ja) | 2019-09-05 |
| JP2022116008A (ja) | 2022-08-09 |
| US12268724B2 (en) | 2025-04-08 |
| CA2916880A1 (en) | 2014-09-04 |
| DK2961420T3 (da) | 2019-10-07 |
| CN115990241A (zh) | 2023-04-21 |
| US20240156892A1 (en) | 2024-05-16 |
| JP7381652B2 (ja) | 2023-11-15 |
| US20210401923A1 (en) | 2021-12-30 |
| JP7072692B2 (ja) | 2022-05-20 |
| US11771734B2 (en) | 2023-10-03 |
| EP2961420A1 (en) | 2016-01-06 |
| HUE046924T2 (hu) | 2020-03-30 |
| US11083772B2 (en) | 2021-08-10 |
| US20200345803A1 (en) | 2020-11-05 |
| JP6518197B2 (ja) | 2019-05-22 |
| EP2961420A4 (en) | 2016-08-17 |
| EP3626252A1 (en) | 2020-03-25 |
| JP2021098704A (ja) | 2021-07-01 |
| CN115990242A (zh) | 2023-04-21 |
| US20160228487A1 (en) | 2016-08-11 |
| US20180147251A1 (en) | 2018-05-31 |
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| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| TA01 | Transfer of patent application right | ||
| TA01 | Transfer of patent application right |
Effective date of registration: 20220627 Address after: Massachusetts, USA Applicant after: Kant biomedical Co.,Ltd. Address before: Monaco City, Monaco Applicant before: STEALTH PEPTIDES INTERNATIONAL, Inc. |
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| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20160316 |