CN105381243A - Rapid hemostasis cotton and making method thereof - Google Patents
Rapid hemostasis cotton and making method thereof Download PDFInfo
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- CN105381243A CN105381243A CN201510926908.XA CN201510926908A CN105381243A CN 105381243 A CN105381243 A CN 105381243A CN 201510926908 A CN201510926908 A CN 201510926908A CN 105381243 A CN105381243 A CN 105381243A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/898—Orchidaceae (Orchid family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/886—Aloeaceae (Aloe family), e.g. aloe vera
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
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Abstract
The invention discloses a rapid hemostasis cotton and a making method thereof, and belongs to the technical field of blood clotting. The rapid hemostasis cotton comprises absorbent cotton and an absorbent cotton dipping solution, and the absorbent cotton dipping solution comprises, by weight, 5-10 parts of Japanese Thistle Herb extract, 5-8 parts of aloe extract, 5-8 parts of Bletilla striata extract and 0.02-0.05 parts of alum. The hemostasis cotton improves traditional methods for stopping bleeding only through using cotton bars containing no medicine components, can rapidly stop bleeding of patients within 2-10s, saves patients' time, avoids troubles brought by long-time pressing of the cotton bars, and allows clothes to be well finished and not contaminated without waiting for a long time in cold seasons.
Description
Technical field
The present invention relates to blood coagulation technical field, is a kind of quick-acting haemostatic powder cotton and preparation method thereof specifically.
Background technology
Hospital laboratory doctor often needs to carry out blood test to patient or examinee, after blood drawing, the traditional method of hemostasis is the blood drawing pin hole on patient's swab stick pressing skin, usually need to pin 1 to 5 minutes, blood drawing place just can be allowed to contact clothes until blood stops completely, otherwise clothes of making dirty.But when it is cold or patient is in a hurry, such Hemostasis is too slow, comparatively waste patient's time, and pressing always also comparatively bothers.In addition, the blood of some patient, due to the reason such as ill, no longer easily stops, and at this time more needs a kind ofly to have can the absorbent cotton of quick-acting haemostatic powder stopping blooding of Blood clotting.
Summary of the invention
For solving the defect that prior art exists, the present invention aim to provide a kind of do not need long-time pressing can a kind of quick-acting haemostatic powder of quick-acting haemostatic powder cotton and preparation method thereof.
To achieve these goals, technical scheme of the present invention is:
A quick-acting haemostatic powder cotton, comprises absorbent cotton and absorbent cotton dips liquid, and the raw material that described absorbent cotton dips liquid is Radix Cirsii Japonici, Aloe, the Pseudobulbus Bletillae (Rhizoma Bletillae) and Alumen.
Preferably, described absorbent cotton dips liquid effective ingredient and is made up of the component of following weight portion:
Herba seu Radix Cirsii Japonici 5-10 part Aloe extract 5-8 part bletilla striata extract 5-8 part Alumen 0.02-0.05 part.
Preferably, described absorbent cotton dips liquid effective ingredient and is made up of the component of following weight portion:
Herba seu Radix Cirsii Japonici 8-10 part Aloe extract 5-6 part bletilla striata extract 5-6 part Alumen 0.02-0.03 part.
Preferably, described absorbent cotton dips liquid effective ingredient and is made up of the component of following weight portion:
Herba seu Radix Cirsii Japonici 9 parts of Aloe extracts 6 parts of bletilla striata extract 6 parts of Alumens 0.035 part.
Preferably, described Herba seu Radix Cirsii Japonici is soak by water 2-4 time adding 3-5 times of weight after Radix Cirsii Japonici chopping, and each 0.5-1 hour, filters, merging filtrate, and when being concentrated into 50 DEG C, relative density is 1.1 obtained.
Preferably, the alcoholic solution reflux, extract, of described Aloe extract to be the volume fraction adding 3-5 times of weight after fresh aloe chopping be 50-75% 2-4 time, each 0.5-1 hour, filters, merging filtrate, and when being concentrated into 50 DEG C, relative density is 1.1 obtained.
Preferably, described bletilla striata extract is soak by water 2-3 time adding 2-5 times of weight in the Pseudobulbus Bletillae (Rhizoma Bletillae), each 0.5-1 hour, filter, merging filtrate, adding alcoholic solution to alcohol content is 40-60%, staticly settle, get supernatant, when being concentrated into 50 DEG C, relative density is 1.1 to obtain.
The preparation method of a kind of quick-acting haemostatic powder cotton provided by the invention, carry out according to following steps:
1) add soak by water 2-4 time of 3-5 times of weight after being shredded by Radix Cirsii Japonici, each 0.5-1 hour, filtration, merging filtrate, when being concentrated into 50 DEG C, relative density is 1.1, obtains Herba seu Radix Cirsii Japonici;
2) volume fraction adding 3-5 times of weight after being shredded by fresh aloe is alcoholic solution reflux, extract, 2-4 time of 50-75%, each 0.5-1 hour, filtration, merging filtrate, and when being concentrated into 50 DEG C, relative density is 1.1, obtains Aloe extract;
3) in the Pseudobulbus Bletillae (Rhizoma Bletillae), add soak by water 2-3 time of 2-5 times of weight, each 0.5-1 hour, filter, merging filtrate, adding alcoholic solution to alcohol content is 40-60%, staticly settles, gets supernatant, and when being concentrated into 50 DEG C, relative density is 1.1, obtains bletilla striata extract;
4) merge Herba seu Radix Cirsii Japonici, Aloe extract and bletilla striata extract, the volume fraction adding 5-20 times of weight is the alcoholic solution dilution of 5-20%, adds Alumen and dissolves, stir, obtain absorbent cotton and dip liquid;
5) absorbent cotton is dipped absorbent cotton and dip liquid, to obtain final product.
Beneficial effect of the present invention is:
1) styptic cotton of the present invention improves traditional method only by the method that the swab stick not adding ingredient is stopped blooding, can be rapidly patient's hemostasis in 2-10s, for patient has saved time and the long-time trouble pressing swab stick and bring, also no longer need the season cold in sky to wait and can put clothes in order too for a long time and clothes of not making dirty.
2) styptic cotton production technology of the present invention is simple, and product quality is easy to control, and is applicable to suitability for industrialized production.
Additional aspect of the present invention and advantage will part provide in the following description, and part will become obvious from the following description, or be recognized by practice of the present invention.
Detailed description of the invention
Below in conjunction with instantiation, the present invention is described in detail.
Embodiment 1
A. raw material is prepared:
Fresh Radix Cirsii Japonici, fresh aloe, the dry Pseudobulbus Bletillae (Rhizoma Bletillae) and Alumen.
B. following steps are adopted to prepare styptic cotton:
1) will add the soak by water 2 times of 3 times of weight after the chopping of fresh Radix Cirsii Japonici, and each 0.5 hour, filter, merging filtrate, when being concentrated into 50 DEG C, relative density is 1.1, obtains Herba seu Radix Cirsii Japonici;
2) volume fraction adding 3 times of weight after being shredded by fresh aloe is the alcoholic solution reflux, extract, 2 times of 50, and 1 hour first time, second time 0.5 hour, filters, merging filtrate, and when being concentrated into 50 DEG C, relative density is 1.1, obtains Aloe extract;
3) shredded by the Pseudobulbus Bletillae (Rhizoma Bletillae), add the soak by water 3 times of 2 times of weight, each 0.5 hour, filter, merging filtrate, adding alcoholic solution to alcohol content is 45%, staticly settles, gets supernatant, and when being concentrated into 50 DEG C, relative density is 1.1, obtains bletilla striata extract;
4) get Herba seu Radix Cirsii Japonici 90g, Aloe extract 60g and bletilla striata extract 60g, the volume fraction adding 10 times of weight after merging is the alcoholic solution dilution of 5%, adds 0.35g Alumen and dissolves, stir, obtain absorbent cotton and dip liquid;
5) absorbent cotton is dipped appropriate absorbent cotton and dip liquid, to obtain final product.
Embodiment 2
A. raw material is prepared:
Dry Radix Cirsii Japonici, fresh aloe, the dry Pseudobulbus Bletillae (Rhizoma Bletillae) and Alumen.
B. following steps are adopted to prepare styptic cotton:
1) add the soak by water 4 times of 4 times of weight after being shredded by Radix Cirsii Japonici, first and second time is 1 hour, and third and fourth time is 0.5 hour, filters, and merges each filtrate decocted, and when being concentrated into 50 DEG C, relative density is 1.1, obtains Herba seu Radix Cirsii Japonici;
2) volume fraction adding 5 times of weight after being shredded by fresh aloe is the alcoholic solution reflux, extract, 4 times of 5%, each 0.5 hour, filters, merging filtrate, and when being concentrated into 50 DEG C, relative density is 1.1, obtains Aloe extract;
3) will add the soak by water 2 times of 5 times of weight in the Pseudobulbus Bletillae (Rhizoma Bletillae), each 0.5 hour, filter, merging filtrate, adding alcoholic solution to alcohol content is 60%, staticly settles, gets supernatant, and when being concentrated into 50 DEG C, relative density is 1.1, obtains bletilla striata extract;
4) get Herba seu Radix Cirsii Japonici 80g, Aloe extract 50g and bletilla striata extract 50g, the volume fraction adding 20 times of weight after merging is the alcoholic solution dilution of 20%, adds 0.2g Alumen and dissolves, stir, obtain absorbent cotton and dip liquid;
5) absorbent cotton is dipped absorbent cotton and dip liquid, to obtain final product.
Embodiment 3
A. raw material is prepared:
Dry Radix Cirsii Japonici, fresh aloe, the dry Pseudobulbus Bletillae (Rhizoma Bletillae) and Alumen.
B. following steps are adopted to prepare styptic cotton:
1) add the soak by water 2 times of 4 times of weight after Radix Cirsii Japonici being concocted into Carbonized Cirsium japonicum chopping, each 0.5 hour, filter, merging filtrate, when being concentrated into 50 DEG C, relative density is 1.1, obtains Herba seu Radix Cirsii Japonici;
2) volume fraction adding 3-5 times of weight after being shredded by fresh aloe is the alcoholic solution reflux, extract, 3 times of 60%, each 0.5 hour, filters, merging filtrate, and when being concentrated into 50 DEG C, relative density is 1.1, obtains Aloe extract;
3) will add the soak by water 2 times of 2 times of weight in the Pseudobulbus Bletillae (Rhizoma Bletillae), each 1 hour, filter, merging filtrate, adding alcoholic solution to alcohol content is 45%, staticly settles, gets supernatant, and when being concentrated into 50 DEG C, relative density is 1.1, obtains bletilla striata extract;
4) get Herba seu Radix Cirsii Japonici 100g, Aloe extract 60g and bletilla striata extract 60g, the volume fraction adding 10 times of weight after merging is the alcoholic solution dilution of 5%, adds 0.3g Alumen and dissolves, stir, obtain absorbent cotton and dip liquid;
5) absorbent cotton is dipped absorbent cotton and dip liquid, to obtain final product.
Embodiment 4
1) obtained in Example 1 Herba seu Radix Cirsii Japonici 50g, Aloe extract 50g and bletilla striata extract 50g, the volume fraction adding 20 times of weight is the alcoholic solution dilution of 10%, adds 0.25g Alumen and dissolves, stir, obtain absorbent cotton and dip liquid;
2) absorbent cotton is dipped absorbent cotton and dip liquid, to obtain final product.
Embodiment 5 effect detection
Experimental technique: randomly draw the patient that 100 health examination personnel and 100 hospitals need blood test, age range is 16-60 year, be divided into 5 groups respectively, often organize 20 people, after arm blood drawing is carried out to it, give the styptic cotton of embodiments of the invention 1, often organize and press 2s respectively, 4s, 6s, 8s, after 10s, observe bleeding, statistics is as table 1, this experiment also arranges matched group, for the laboratory personnel that comes of Stochastic choice, comprise patient and Healthy People, totally 100 people, adding up it, to use traditional common swab stick to press the number of stopping blooding in 10s be 57 people, gross hemostasis rate is 57%.
Table 1 each group of personnel's bleeding stopping period statistical table
From table 1, styptic cotton of the present invention can be the quick staunch blood of assayer in 8s, and the gross hemostasis rate wherein in Healthy People 6s is 100%.Gross hemostasis rate in patient 8s is 100%, and compared to matched group, anastalsis is rapid,
Although illustrate and describe embodiments of the invention, those having ordinary skill in the art will appreciate that: can carry out multiple change, amendment, replacement and modification to these embodiments when not departing from principle of the present invention and aim, scope of the present invention is by claim and equivalents thereof.
Claims (8)
1. a quick-acting haemostatic powder cotton, comprises absorbent cotton and absorbent cotton dips liquid, it is characterized in that, the raw material that described absorbent cotton dips liquid is Radix Cirsii Japonici, Aloe, the Pseudobulbus Bletillae (Rhizoma Bletillae) and Alumen.
2. a kind of quick-acting haemostatic powder according to claim 1 is cotton, and it is characterized in that, described absorbent cotton dips liquid effective ingredient and is made up of the component of following weight portion:
Herba seu Radix Cirsii Japonici 5-10 part Aloe extract 5-8 part bletilla striata extract 5-8 part Alumen 0.02-0.05 part.
3. a kind of quick-acting haemostatic powder according to claim 1 is cotton, and it is characterized in that, described absorbent cotton dips liquid effective ingredient and is made up of the component of following weight portion:
Herba seu Radix Cirsii Japonici 8-10 part Aloe extract 5-6 part bletilla striata extract 5-6 part Alumen 0.02-0.03 part.
4. a kind of quick-acting haemostatic powder according to claim 1 is cotton, and it is characterized in that, described absorbent cotton dips liquid effective ingredient and is made up of the component of following weight portion:
Herba seu Radix Cirsii Japonici 9 parts of Aloe extracts 6 parts of bletilla striata extract 6 parts of Alumens 0.035 part.
5. a kind of quick-acting haemostatic powder according to any one of claim 2-4 is cotton, it is characterized in that, described Herba seu Radix Cirsii Japonici is soak by water 2-4 time adding 3-5 times of weight after Radix Cirsii Japonici chopping, each 0.5-1 hour, filter, merging filtrate, when being concentrated into 50 DEG C, relative density is 1.1 to obtain.
6. a kind of quick-acting haemostatic powder according to any one of claim 2-4 is cotton, it is characterized in that, the alcoholic solution reflux, extract, of described Aloe extract to be the volume fraction adding 3-5 times of weight after fresh aloe chopping be 50-75% 2-4 time, each 0.5-1 hour, filter, merging filtrate, when being concentrated into 50 DEG C, relative density is 1.1 to obtain.
7. a kind of quick-acting haemostatic powder according to any one of claim 2-4 is cotton, it is characterized in that, described bletilla striata extract is soak by water 2-3 time adding 2-5 times of weight in the Pseudobulbus Bletillae (Rhizoma Bletillae), each 0.5-1 hour, filters, merging filtrate, adding alcoholic solution to alcohol content is 40-60%, staticly settle, get supernatant, when being concentrated into 50 DEG C, relative density is 1.1 to obtain.
8. the preparation method of a kind of quick-acting haemostatic powder cotton according to any one of claim 1-7, is characterized in that, carry out according to following steps:
1) add soak by water 2-4 time of 3-5 times of weight after being shredded by Radix Cirsii Japonici, each 0.5-1 hour, filtration, merging filtrate, when being concentrated into 50 DEG C, relative density is 1.1, obtains Herba seu Radix Cirsii Japonici;
2) volume fraction adding 3-5 times of weight after being shredded by fresh aloe is alcoholic solution reflux, extract, 2-4 time of 50-75%, each 0.5-1 hour, filtration, merging filtrate, and when being concentrated into 50 DEG C, relative density is 1.1, obtains Aloe extract;
3) in the Pseudobulbus Bletillae (Rhizoma Bletillae), add soak by water 2-3 time of 2-5 times of weight, each 0.5-1 hour, filter, merging filtrate, adding alcoholic solution to alcohol content is 40-60%, staticly settles, gets supernatant, and when being concentrated into 50 DEG C, relative density is 1.1, obtains bletilla striata extract;
4) merge Herba seu Radix Cirsii Japonici, Aloe extract and bletilla striata extract, the volume fraction adding 5-20 times of weight is the alcoholic solution dilution of 5-20%, adds Alumen and dissolves, stir, obtain absorbent cotton and dip liquid;
5) absorbent cotton is dipped absorbent cotton and dip liquid, to obtain final product.
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| CN201510926908.XA CN105381243A (en) | 2015-12-11 | 2015-12-11 | Rapid hemostasis cotton and making method thereof |
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| CN201510926908.XA CN105381243A (en) | 2015-12-11 | 2015-12-11 | Rapid hemostasis cotton and making method thereof |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106729926A (en) * | 2016-11-25 | 2017-05-31 | 天津市第三中心医院 | A kind of antibacterial sorptivety liquid natural polysaccharide wound repair material and preparation method thereof |
| CN109833148A (en) * | 2017-11-29 | 2019-06-04 | 江苏双盛医疗器械有限公司 | A kind of medical hemostatic cotton balls |
| CN109833510A (en) * | 2017-11-29 | 2019-06-04 | 江苏尚铖医疗器械有限公司 | A kind of quick-acting haemostatic powder ball |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101530561A (en) * | 2009-04-10 | 2009-09-16 | 王文昇 | Hemostyptic medicine |
| CN101584721A (en) * | 2009-07-06 | 2009-11-25 | 江苏泰灵生物科技有限公司 | Chinese traditional medicine antibiotic hemostatic plaster |
| CN103285238A (en) * | 2013-06-05 | 2013-09-11 | 冯欢庆 | Traditional Chinese medicine for stopping bleeding |
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2015
- 2015-12-11 CN CN201510926908.XA patent/CN105381243A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101530561A (en) * | 2009-04-10 | 2009-09-16 | 王文昇 | Hemostyptic medicine |
| CN101584721A (en) * | 2009-07-06 | 2009-11-25 | 江苏泰灵生物科技有限公司 | Chinese traditional medicine antibiotic hemostatic plaster |
| CN103285238A (en) * | 2013-06-05 | 2013-09-11 | 冯欢庆 | Traditional Chinese medicine for stopping bleeding |
Non-Patent Citations (1)
| Title |
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| 孙美珍等: "《骨伤科病实用方》", 30 September 1993, 江苏科学技术出版社 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106729926A (en) * | 2016-11-25 | 2017-05-31 | 天津市第三中心医院 | A kind of antibacterial sorptivety liquid natural polysaccharide wound repair material and preparation method thereof |
| CN109833148A (en) * | 2017-11-29 | 2019-06-04 | 江苏双盛医疗器械有限公司 | A kind of medical hemostatic cotton balls |
| CN109833510A (en) * | 2017-11-29 | 2019-06-04 | 江苏尚铖医疗器械有限公司 | A kind of quick-acting haemostatic powder ball |
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Application publication date: 20160309 |