CN105380124A - Production method of animal liver powder containing selenium active substances - Google Patents
Production method of animal liver powder containing selenium active substances Download PDFInfo
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Classifications
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23B—PRESERVING, e.g. BY CANNING, MEAT, FISH, EGGS, FRUIT, VEGETABLES, EDIBLE SEEDS; CHEMICAL RIPENING OF FRUIT OR VEGETABLES; THE PRESERVED, RIPENED, OR CANNED PRODUCTS
- A23B7/00—Preservation or chemical ripening of fruit or vegetables
- A23B7/04—Freezing; Subsequent thawing; Cooling
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
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- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The invention relates to a production method of animal liver powder containing selenium active substances and belongs to the field of preparation of a functional health food and a biochemical product. The production method comprises the following steps: carrying out quick freezing, inactivation, freshness keeping and preservation on collected fresh animal livers containing the selenium active substances; slicing under a quick freezing condition; smashing slices by using a stirrer and carrying out rough filtering by a filter screen to remove blood vessels, tendon-shaped matters, animal liver tunica externa and wastes in the animal livers; adding the animal livers containing the selenium active substances, which are subjected to rough filtering, purification and waste removal into a grinding machine to be ground, and further filtering; adding the filtered animal liver fine slurry into a low-temperature spray drying machine to carry out low-temperature spray drying to obtain the liver powder containing the selenium active substances; and sealing and packaging. The equipment and process are simple and the quality of the selenium active substances is remained to the greatest extent, and the functionality, effectiveness and practical value of the product are improved; and meanwhile, the production cost is low, and blanks of industrial and large-scale processing and production, and accurate application of animal liver medicines and foods in China are filled up.
Description
Technical field
The present invention relates to a kind of preparation method of active Se-containing substance animal liver meal, belong to the preparation field of functional health-care food and biochemical product.
Background technology
In recent years, along with the development of science and technology and the enforcement of circular economy policy, with accessory substances such as plucks for raw material, exploitation internal organs biochemical product and food add main trend and the new industry that auxiliary material has become animal derived product, because animal sources biochemical product derives from animal, compared with chemical synthesis goods, it is little that this series products has toxic and side effect, be easy to the advantages such as absorption of human body, become one of study hotspot of food circle and the world of medicine at present.
Biochemical drug has two basic characteristics: one, and it is from organism; Its two, it is the basic biochemical component of organism.This kind of medicine mainly contains amino acids, polypeptide protein class, nucleic acid, polysaccharide, lipid and cell growth regulator etc., use pointed strong, evident in efficacy, the advantage such as toxic and side effect is little, the effect of alternative medicine can be played preferably, be widely used in clinical at present.
Animal viscera is utilized to prepare health food, feed, biochemical drug for raw material, existing history for many years.Particularly animal viscera is utilized to prepare food additives in the state such as American-European, Japanese, as foreign study with hepar siccatum as the carrier of immobilised enzymes, beta galactosidase and amylase are fixed on hepar siccatum, are applied to food industry, produce syrup, reach extraordinary effect.
Along with the raising that people are familiar with Animal Liver medical value, and the application of modern biotechnology in drug research, the research and development of animal viscera natural drug progressively deeply, the research of Animal Liver medical value is obtained gradually to the attention of increasing chemist and medicine scholar, many novel structures, active unique compound are therefrom found, one of focus becoming researches on natural drugs.Meanwhile, due to the special status that animal is residing on evolving, it is subject to again animal scholar, the showing great attention to of darwinist, and therefore, the exploitation of the medical value of animal viscera become the focus that scientific worker competitively studies.Although in recent years about the research of its medical value obtains greater advance, the compound in a large number with Antitumor virus, antibacterial, anti-inflammatory and enzyme inhibition activity is found, also not enough to the exploitation of a part of internal organs.Therefore, need to make full use of more new and high technology and develop new medicine, create larger economic benefit and social benefit.
Animal Liver is the biochemical apparatus of animal organism, and liver is maximum chemical plant, can synthesize several physiological active substances, as bile, superoxide dismutase etc., has the typical nutritional labeling of animal organ.Physiological activator is the active material had an impact to human or animal's physiological phenomenon.Such as transmitter substance acetylcholine, nerve growth factor, polypeptide, polysaccharide, various active enzyme, enzyme unit etc. are all physiological activators, coenzyme, subsidiary engine, etc. be all the part of physiological activator.
The United Nations's health organization is pointed out: " meal ingestion selenium is optimal benefit selenium mode." from then on opened global research selemium nutrition, developed the new page of selenium-rich function food.Infer according to great many of experiments; harmful peroxide is mainly reduced to harmless hydroxy compounds by GSH-Px by the anticancer mechanism of selenium; thus protect the 26S Proteasome Structure and Function of cell membrane; catch free radical; reduce the activity of some hydroxylase that can activate carcinogen (such as aryl hydroxylase); reduce mutagenicity, repair DNA, thus reach anti-cell canceration.When the numerous diseases such as current cancer are without specific drug, carry out prevention of various diseases seem particularly important by absorbing enough selenium.But multiple selenium-containing compound has extremely strong toxicity, improper use containing selenium material, all will damage body.The exploitation of current active Se-containing substance has wide actual application value, major product form is food, functional food, health products etc., and research and development active Se-containing substance must be based upon on the research of the physiological action of selenium, the biological cycle of selenium and bio-organic.The function of active Se-containing substance, consumption and Toxicity Monitoring and evaluation must be carried out.
Selenium is the required trace element of humans and animals, and it has various biological function, as anti-oxidant, immune, participate in the reproduction of animal and the secretion etc. of thyroid hormone.In recent years, because Organic Selenium toxicity is less, bioavailability is high, its application receives extensive concern.Organic Selenium can significantly improve the Se contents such as blood plasma, liver, muscle, and effect is better than inorganic selenium; Liver is removing toxic substances organ important in animal body, in digestion, absorb, biological transform and all kinds of material metabolism in play an important role.In liver, iron content enriches, and vitamin A (VA) content far exceedes milk, egg, fish, meat etc., often eats and plays an important role to supplementary important coenzyme and removing toxic substances.Accelerating the function animal viscera biochemical drug Development Base pace of construction of active Se-containing substance and the production base scale of functional food animal, is food enterprise developing direction.
From the scientific seminar both at home and abroad about selenium, the first selenium is one of trace element of needed by human, and selenium plays important biological function in human body, and scarce selenium can cause the forfeiture of some function of human body and human body the weakening of adaptive capacity to external world; The second, selenium is in antitumor, raising immunity of organisms, anti-ageing and angiocardiopathy, and prevent Keshan disease and the sick aspects of joint, that has studied mechanism is more clearly; 3rd, selenium health food development is in recent years very fast, especially domestic market has occurred the health food of many selenium aspects, but has still lacked standard at present as selenium-enriched food, market differs tens times even tens times between different product, relevant criterion should be made as early as possible; 4th, although selenium is the trace element of needed by human, excess intake, especially the toxicity of inorganic selenium to human body is very large, and utilize the rich selenium of organism, producing se-rich health food products is one production ways safely and efficiently.
Selenium, as the essential trace element of humans and animals, participates in many important vital movement processes in body.It is the bioactive ingredients of the sweet skin peroxidase of paddy moon bright, selenoprotein one P, I type 5 one deoxygenase, protects body from oxidative damage in vivo, accelerates body and removes harmful free radicals and the integrality of Cell protection film.Have and improve the biological functions such as body is anti-oxidant, anticancer, antitumor.Therefore, the quality of research active Se-containing substance hepar siccatum, anti-oxidation function and other biological function, namely carry out active Se-containing substance antioxidation activity in vivo, the actual effect scientific experiments such as inside and outside active anticancer.More complete in order to realize selenium active material quality standardization, digestion, absorption in selenium active material hepar siccatum, develop safety, efficient organic Selenium supplement agent, more related experiment still needs to carry out.
At present, the making of general animal liver meal is by animal's liver, invades bubble and removes fishy smell, add condiment, boil rear section, airing or oven dry, naturally cool, make powder product after crushed after cleaning with wine.This method is only applicable to the processing of common animal's liver raw material, if for the making of active Se-containing substance animal liver meal, can cause a large amount of loss and the destruction of active Se-containing substance.
Summary of the invention
Inventor, through concentrating on studies for many years, filters out ideal Enriching Selenium, the carrier of the selenium that organises, active Se-containing substance meticulously.Mainly adopt selenium biological cycle principle, to add a certain amount of selenium element by manual control in animal feed, selenium element is by living animal biochemical process, be converted into the active Se-containing substance animal's liver with certain mass, and then the animal's liver of this active Se-containing substance is produced a kind of functional hepar siccatum eating medicine dual-purpose as raw material.In order to adopting active Se-containing substance animal's liver to make in the process of hepar siccatum as raw material, farthest reducing loss and the destruction of active Se-containing substance, the invention provides a kind of preparation method of new active Se-containing substance animal liver meal.
The preparation method of active Se-containing substance animal liver meal of the present invention, by raw material through quick-frozen deactivation, freezing microtome section, blend coarse filtration purification impurity elimination, defibrination filters, low temperature spray drying, pack, make the hepar siccatum product of active Se-containing substance, this product has special functional nutritional value with its active Se-containing substance, unrighted acid and rare element, belongs to the additive of following high-end nutraceutical or high-end nutraceutical.
A preparation method for active Se-containing substance animal liver meal, adopts active Se-containing substance animal's liver to be raw material, and its processing process comprises the steps:
(1) quick-frozen deactivation: the animal's liver of the fresh active Se-containing substance gathered is carried out the fresh-keeping preservation of quick-frozen deactivation;
(2) freezing microtome section: the animal's liver of the active Se-containing substance of fresh-keeping for quick-frozen deactivation preservation is under freezing conditions cut into slices;
(3) coarse filtration impurity elimination is blended: adopt mixer the section of active Se-containing substance animal's liver to be blended, carry out coarse filtration through filter screen, by filterings such as the blood vessel in Animal Liver, muscle shape thing, Animal Liver adventitia and foreign material;
(4) defibrination filters: coarse filtration is purified the active Se-containing substance animal's liver after impurity elimination and add defibrination in fiberizer, then filter further;
(5) low temperature spray drying: Animal Liver screened stock after filtration is added in low temperature spray drying machine, carries out low temperature spray drying, obtain active Se-containing substance hepar siccatum;
(6) pack.
In step (1), the temperature of the described fresh-keeping preservation of quick-frozen deactivation is-35 DEG C ~-45 DEG C, and temperature retention time can be preferably 24-48 hour.The animal's liver of active Se-containing substance can be pork liver, sheep liver, chicken gizzard etc.
In step (3), described coarse filtration adopts 30 ~ 40 object strainer filterings.
In step (4), described further filtration employing 80 ~ 120 object strainer filtering.
In step (5), the temperature of described low temperature spray drying is 80 DEG C ~ 110 DEG C.
The survey report display provided by national meat product Quality Supervision and Inspection Center, the Se content of the active Se-containing substance hepar siccatum that the inventive method prepares is: 8.2 ㎎/㎏-14.1 ㎎/㎏.
The present invention utilizes quick-frozen deactivation, freezing microtome section, and blend coarse filtration purification impurity elimination, defibrination filters, low temperature spray drying technique, and the functional health-care food producing active Se-containing substance is a kind of simple and practical reliable method.Adopt quick-frozen deactivation and low temperature spray drying technique not only can make food fresh keeping, and significantly reduce the loss of selenium, the loss of Se content in the inventive method processing products obtained therefrom, its average loss rate is that 8.06%-9.20% (w%) can retain selenium-containing biological active material to greatest extent, ensures that in hepar siccatum, Se content is 8.2 ㎎/㎏-14.1 ㎎/㎏.
The production method of this active Se-containing substance animal liver meal, equipment, technique are simple, remain active Se-containing substance quality to greatest extent, improve functional, validity and the practical value of product.Meanwhile, low production cost, fills up domestic animals liver medicine, the industrialization of food, scale processing, precisely applies blank.
Below by the drawings and specific embodiments, the present invention will be further described, but and do not mean that limiting the scope of the invention.
Accompanying drawing explanation
Fig. 1 is the flow process chart of active Se-containing substance animal liver meal preparation method of the present invention.
Detailed description of the invention
As shown in Figure 1, the present invention adopt active Se-containing substance animal's liver be raw material to make hepar siccatum, its processing treatment step comprises: (1) quick-frozen deactivation: by go out chamber gather after the animal's liver of fresh active Se-containing substance be placed on the fresh-keeping preservation of quick-frozen deactivation under the condition of-35 DEG C to-45 DEG C; (2) freezing microtome section: the quick-freezing fresh-keeping active Se-containing substance animal's liver as raw material is under freezing conditions cut into slices; (3) coarse filtration impurity elimination is blended: the section of active Se-containing substance animal's liver blended by mixer, filter, by filterings such as the blood vessel in Animal Liver, muscle shape thing, Animal Liver adventitia and foreign material through 30-40 mesh filter screen; (4) defibrination filters: coarse filtration is purified the active Se-containing substance animal's liver after impurity elimination and add defibrination in fiberizer, then filter through 80-120 mesh filter screen; (5) low temperature spray drying: Animal Liver screened stock after filtration is added in low temperature spray drying machine, complete the generation of active Se-containing substance hepar siccatum at 80 DEG C-110 DEG C; (6) pack.
Embodiment 1
Adopt active Se-containing substance pig liver be raw material to make hepar siccatum, its processing treatment step comprises: (1) by go out chamber gather after the pig liver of fresh active Se-containing substance be placed on-35 DEG C at the fresh-keeping preservation of quick-frozen deactivation 48 hours; (2) the quick-freezing fresh-keeping active Se-containing substance pig liver as raw material is under freezing conditions cut into slices; (3) by mixer, the section of active Se-containing substance pig liver is blended, filter, by filterings such as the blood vessel in pork liver, muscle shape thing, pork liver adventitia and foreign material through 30 mesh filter screens; (4) coarse filtration is purified the active Se-containing substance pig liver after impurity elimination and add defibrination in fiberizer, then filter through 90 mesh filter screens; (5) Animal Liver screened stock after filtration is added in low temperature spray drying machine, at 80 DEG C, complete the generation of active Se-containing substance hepar siccatum; (6) pack.
Through the inspection of national meat product Quality Supervision and Inspection Center, the Se content of the active Se-containing substance hepar siccatum prepared is: 8.2 ㎎/㎏; After this method process, the loss late of liver magma Se content in low temperature spray drying hepar siccatum is 9.20% (w%).
Embodiment 2
Adopt active Se-containing substance pig liver be raw material to make hepar siccatum, its processing treatment step comprises: (1) by go out chamber gather after the pig liver of fresh active Se-containing substance be placed on-45 DEG C at the fresh-keeping preservation of quick-frozen deactivation 24 hours; (2) the quick-freezing fresh-keeping active Se-containing substance pig liver as raw material is under freezing conditions cut into slices; (3) by mixer, the section of active Se-containing substance pig liver is blended, filter, by filterings such as the blood vessel in pork liver, muscle shape thing, pork liver adventitia and foreign material through 40 mesh filter screens; (4) coarse filtration is purified the active Se-containing substance pig liver after impurity elimination and add defibrination in fiberizer, then filter through 120 mesh filter screens; (5) Animal Liver screened stock after filtration is added in low temperature spray drying machine, at 110 DEG C, complete the generation of active Se-containing substance hepar siccatum; (6) pack.
Through the inspection of national meat product Quality Supervision and Inspection Center, the Se content of the active Se-containing substance hepar siccatum prepared is: 14.1 ㎎/㎏; After this method process, the loss late of liver magma Se content in low temperature spray drying hepar siccatum is 8.06% (w%).
The present invention by by go out chamber gather after the animal's liver of fresh active Se-containing substance be placed on the fresh-keeping preservation of quick-frozen deactivation under the condition of-35 DEG C to-45 DEG C, in Cell protection film and food various organize the prerequisite be not damaged under carry out IQF.So, the hydrone in food can not expand substantially, can not cause cell wall rupture, and arrangement is evenly, suppresses the acidifying of food and rotten, thus food after thawing just with freezing before equally fresh.Through experimental verification, after-12 DEG C of refrigeration two weeks, selenium loss late is 6.05%-12.18% (w%).After-25 DEG C of refrigeration two weeks, selenium loss late is 4.32% ~ 7.2% (w%).After-35 DEG C of refrigeration two weeks, selenium loss late is 0.25%-0.81% (w%).
The present invention is studied containing selenium liver the process of employing different process in process of experimental, to Se content test in liver, result shows: poach process can cause the loss of Se content in liver, its average loss rate is 30.13%-32.28% (w%), high pressure cooking process can cause the loss of Se content in liver, and its average loss rate is 41.04%-47.27% (w%).Boil rear section, airing, mechanical crushing, the loss of Se content in hepar siccatum, its average loss rate is 27.7%-28.13% (w%).Liver magma of the present invention prepares the loss of Se content in hepar siccatum through low temperature spray drying, its average loss rate is 8.06%-9.20% (w%).
The present invention achieves the wink-dry cryogenic conditions 80 DEG C-110 DEG C containing selenium animal's liver magma, greatly reduces energy resource consumption, has cut off pollution sources.The problems such as solve and contain various bioactivators containing in selenium animal's liver, magma viscosity is high, and thermo-labile, extraction active material difficulty is large.For retaining selenium-containing biological active material to greatest extent, in hepar siccatum, Se content test result is 8.2 ㎎/㎏-14.1 ㎎/㎏.Low temperature spray drying is that the production of selenium-containing biological active material hepar siccatum provides very convenient very safe drying means.
The production method of active Se-containing substance animal liver meal of the present invention, relates to technology maturation, home-made equipment, technique simply, retains active Se-containing substance quality to greatest extent, improve functional, validity, the practical value of product.Low production cost, fills up domestic animals liver medicine, the industrialization of food, scale processing, precisely applies blank.
The present invention utilizes quick-frozen deactivation, freezing microtome section, and blend coarse filtration purification impurity elimination, defibrination filters, low temperature spray drying technique, and the functional health-care food producing active Se-containing substance is a kind of simple and practical reliable method.The present invention relies on advanced production technology, perfect quality system and first-class production equipment, produce collection from the manual control of raw material and be worked into finished product packing storage output overall process, all through screening meticulously, be rigid in checking up layer by layer, guarantee to be perfectly safe and active Se-containing substance quality, to realize functional, validity, the practicality of product quality for benchmark, product is all managed production in strict accordance with national QS standard and HACCP international food security management system, and meets GMP standard processing the strictest in the world.With reference to the GB13105-91 " selenium in food tolerance limit " that country promulgates, the authoritative index of " DRIs " and relevant laws and regulations, aim at the accesary foods that inferior health colony provides high-quality.
Claims (7)
1. a preparation method for active Se-containing substance animal liver meal, comprises the steps:
(1) animal's liver of the fresh active Se-containing substance gathered is carried out the fresh-keeping preservation of quick-frozen deactivation;
(2) animal's liver of the active Se-containing substance of fresh-keeping for quick-frozen deactivation preservation is under freezing conditions cut into slices;
(3) adopt mixer the section of active Se-containing substance animal's liver to be blended, carry out coarse filtration through filter screen, by the blood vessel in Animal Liver, muscle shape thing, Animal Liver adventitia and foreign material filtering;
(4) coarse filtration is purified the active Se-containing substance animal's liver after impurity elimination and add defibrination in fiberizer, then filter further;
(5) Animal Liver screened stock after filtration is added in low temperature spray drying machine, carry out low temperature spray drying, obtain active Se-containing substance hepar siccatum;
(6) pack.
2. the preparation method of active Se-containing substance animal liver meal according to claim 1, is characterized in that: the temperature of the described fresh-keeping preservation of quick-frozen deactivation is-35 DEG C ~-45 DEG C.
3. the preparation method of active Se-containing substance animal liver meal according to claim 2, is characterized in that: the temperature retention time of the described fresh-keeping preservation of quick-frozen deactivation is 24-48 hour.
4. the preparation method of active Se-containing substance animal liver meal according to claim 1, is characterized in that: the animal's liver of described active Se-containing substance is pork liver, sheep liver or chicken gizzard.
5. the preparation method of active Se-containing substance animal liver meal according to claim 1, is characterized in that: described coarse filtration adopts 30 ~ 40 object strainer filterings.
6. the preparation method of active Se-containing substance animal liver meal according to claim 1, is characterized in that: described further filtration employing 80 ~ 120 object strainer filtering.
7. the preparation method of active Se-containing substance animal liver meal according to claim 1, is characterized in that: the temperature of described low temperature spray drying is 80 DEG C ~ 110 DEG C.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106616427A (en) * | 2016-12-27 | 2017-05-10 | 江苏千药堂国医研究院有限公司 | Nutrition and health care food rich in vitamin B12 and preparation method thereof |
| CN112617025A (en) * | 2020-12-11 | 2021-04-09 | 桐城市雨润生物科技有限公司 | Preparation method and application of animal viscera powder |
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| CN1830319A (en) * | 2006-04-26 | 2006-09-13 | 张宏 | Manufacturing method of goose liver powder |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106616427A (en) * | 2016-12-27 | 2017-05-10 | 江苏千药堂国医研究院有限公司 | Nutrition and health care food rich in vitamin B12 and preparation method thereof |
| CN112617025A (en) * | 2020-12-11 | 2021-04-09 | 桐城市雨润生物科技有限公司 | Preparation method and application of animal viscera powder |
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