CN105379709A - Deratting plaster and preparation method therefor - Google Patents

Deratting plaster and preparation method therefor Download PDF

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Publication number
CN105379709A
CN105379709A CN201510678992.8A CN201510678992A CN105379709A CN 105379709 A CN105379709 A CN 105379709A CN 201510678992 A CN201510678992 A CN 201510678992A CN 105379709 A CN105379709 A CN 105379709A
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CN
China
Prior art keywords
coumatetralyl
paste
mouse
deratting
plaster
Prior art date
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Granted
Application number
CN201510678992.8A
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Chinese (zh)
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CN105379709B (en
Inventor
刘正伟
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Hebei Yanheng Environmental Protection Technology Co Ltd
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Hebei Yanheng Environmental Protection Technology Co Ltd
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Priority to CN201510678992.8A priority Critical patent/CN105379709B/en
Publication of CN105379709A publication Critical patent/CN105379709A/en
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Publication of CN105379709B publication Critical patent/CN105379709B/en
Expired - Fee Related legal-status Critical Current
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    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/02Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests containing liquids as carriers, diluents or solvents
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N43/00Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
    • A01N43/02Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
    • A01N43/04Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom
    • A01N43/14Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom six-membered rings
    • A01N43/16Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom six-membered rings with oxygen as the ring hetero atom

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  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Pest Control & Pesticides (AREA)
  • Plant Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Dentistry (AREA)
  • Agronomy & Crop Science (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Toxicology (AREA)
  • Catching Or Destruction (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

The present invention relates to a deratting plaster and a preparation method therefor. The deratting plaster is made up of the following raw materials in parts by weight: 0.03-0.05 part of coumatetralyl; 1-2 parts of bromadiolone mother liquor; 85-95 parts of lubricating grease; and 8-12 parts of spindle oil. The preparation method comprises: after the above raw materials are weighed based on parts by weight, adding absolute ethanol into coumatetralyl with stirring to dissolved, so as to obtain a coumatetralyl solution; and mixing the obtained resulting coumatetralyl solution and 0.5% bromadiolone mother liquor evenly, adding spindle oil and lubricating grease with stirring evenly, so as to obtain the deratting plaster. The deratting plaster of the present invention requires a long time to be air-dried and hardened, less dosing frequency and a long dosing interval, without causing rats to be alert, so that the rats can be effectively eliminated with a low safety risk.

Description

One kills mouse paste and preparation method thereof
Technical field
The invention belongs to the preparation field of rodent poison bait, be specifically related to one and kill mouse paste and preparation method thereof.
Background technology
Killing mouse with rodent poison bait is the method be most widely used, and is normally mixed with bait formulation and searches for food for mouse.But the method has very large shortcoming: 1, must treat that mouse eats automatically could effectively, and prolonged application kills mouse bait formulation, makes mouse produce alertness and refuse the edible admixture bait formulation of rodent poison bait; 2, bait formulation easily because feed infested, go mouldy and lost efficacy.For address these problems application number be 201010129940.2 Chinese patent propose a kind of stamping-contact anticoagulant powder rodent poison bait, rodent poison bait is spilt in pipeline and wall limit place, after muroid tramples this medicine, and sharp muroid licks the habit of stinging front and back pawl, medicine is made a gift to someone in the mouth of mouse, thus causes its poisoning hemorrhage death.These class methods solve the drawback no longer eaten because muroid produces vigilance to poison bait, but its medicament is pulvis, and sticky dose when mouse is trampled on pawl is very little, is difficult to reach lethal dose; In addition, in the process of blowing, pulvis easily flies away with the wind, causes potential potential safety hazard.
Therefore, need development one can not cause muroid vigilance, can effectively kill mouse, and the mouse killing agent that security risk is low.
Summary of the invention
The object of the invention is to the defect overcoming prior art, provide one to kill mouse paste and preparation method thereof, this paste that kills mouse can not cause the vigilance of muroid, can effectively go out except muroid, and security risk is low.
To achieve these goals, the technical scheme taked of the present invention is as follows:
One kills mouse paste, and it is made up of following raw material:
Further, it is made up of following raw material:
A preparation method for the above-mentioned paste that kills mouse, it comprises the following steps:
Step one, take above-mentioned raw materials by weight after, in coumatetralyl, add absolute ethyl alcohol, be stirred to dissolving, obtain coumatetralyl solution;
Step 2, the coumatetralyl solution of gained is mixed with 0.5% Bromadiolone mother liquid after, add bobbin oil and lubricating grease, stir, must kill mouse paste.
In the present invention:
Coumatetralyl: have another name called coumatetralyl, gram mouse stands, Racumin, and kill mouse naphthalene, sodoku is dead; Chemical name: 4-hydroxyl-3-(1,2,3,4-tetrahydrochysene-1-naphthyl) coumarin, for clear crystal powder, fusing point 172-176 DEG C, water insoluble, be slightly soluble in benzene, toluene and ether, be dissolved in ethanol and acetone, be dissolved in alkalies and generate salt, stable at 150 DEG C, expose and decompose in the aqueous solution in the sun or under ultraviolet light.
Coumatetralyl belongs to first generation anti-coagulant rodenticide, chronic, wide spectrum, efficient good palatability, exactly alike intoxicating phenomenon.It can destroy coagulation function, and infringement capilary, causes internal haemorrhage, die of exhaustion after 3-6 days.Effectively can kill mouse kind warfarin being had to resistance.
Bromadiolone: have another name called Le Wantong, bromadiolone; Chemical name: 3-(3-(4-bromo-(1,1-biphenyl)-4-base)-3-hydroxyl-1-phenylpropyl)-4-hydroxyl-2H-1-chromen-2-one; Water-soluble, ethanol, ethyl acetate, dimethyl formamide.This product is second generation anti-coagulant rodenticide, finally causes mouse poisoning hemorrhage and dead by suppressing the formation of the necessary prothrombin of blood coagulation.Stronger than 1st generation anti-coagulant rodenticide acute toxicity, working concentration is low, and mouse kind 1st generation anticoagulant being produced to resistance is effective.
Lubricating grease: be add at base oil the semisolid machine components lubricant that thickener and lubricating additive make.Lubricating grease is commonly called as butter, butter because lubricating grease is semi-solid fatty material and mostly in deep mixed yellow ~ milky, the cream of commonly seeing with common people, butter the spitting image of, thus gain the name.
Bobbin oil has another name called main shaft oil, is low viscosity spindle bearing oil, adopts height refining base mineral oil, and adds peace and quiet, dispersion, wear-resistant, antioxygen, anticorrosive, anti-bubble etc. multiple efficient additive is refining and form.
Compared with prior art, the invention has the beneficial effects as follows:
1, the present invention will kill mouse composition first generation anti-coagulant rodenticide coumatetralyl and second generation anti-coagulant rodenticide Bromadiolone is used for killing muroid simultaneously, two generation rodenticide act on simultaneously, be easier to kill the muroid having produced drug resistance, applied widely, killing mouse effect, more singly to adopt one to kill mouse composition effective.
2, adopt lubricating grease and bobbin oil as paste substrate in the present invention, it adopts more separately lubricating grease or adopts vaseline and No. 20 machinery oil to do paste substrate, extends the air-dry sclerosis required time of paste.After the air-dry sclerosis of described paste refers to that paste is brushed, along with the prolongation of time, the volatilization of liquid component in paste, paste becomes dry, and the hardening exsiccation under the effect of the environmental condition such as temperature, illumination of the composition in paste, thus make it lose viscosity is become solid phenomenon by colloidal paste.
3, the present invention kill mouse paste brush after air-dry sclerosis required time extend, thus avoid frequent dispensing, avoid the frequent living environment changing muroid and be familiar with, thus avoid muroid and produce vigilance because of the change of living environment, thus get around the brushing regional activity of the paste that kills mouse.
4, rat eradication device of the present invention is made as: when muroid is out movable, and can touch on limbs and fur and adhere to the paste that kills mouse, then utilize muroid to like licking the characteristic of stinging front and back pawl, the paste that will kill mouse is sent in mouth, thus causes being poisoned to death of muroid.
5, the present invention is paste, avoids the potential potential safety hazard caused because the pulvis adopted disperses with the wind in prior art; It also avoid because pulvis not easily adheres on muroid limbs, the dosage caused is not enough and affect deratization effect, even because long-term low dose administration causes the enhancing of muroid drug resistance.
The present invention's paste air-dry sclerosis required time that kills mouse is long, and dispensing number of times is few, and the dosing interval time is long, can not cause the vigilance of muroid, can effectively go out except muroid, and security risk is low.
Embodiment
Raw materials used in the present invention:
The former medicine of coumatetralyl: purity is 97%, purchased from Hubei Yuancheng Saichuang Technology Co., Ltd.;
0.5% Bromadiolone mother liquid: purchased from Kaifeng Planck biochemistry corporation,Ltd.;
Lubricating grease: what the embodiment of the present invention adopted is the general calcium-base grease of 3#, purchased from Huaming, Dezhou City Shandong Province grease Co., Ltd;
Bobbin oil: what the embodiment of the present invention adopted is Mobil Wei Luosi No. 10 bobbin oil, purchased from Ke Ruida lubricating oil Co., Ltd of Shenzhen.
Below in conjunction with embodiment, detailed further describing is carried out to the present invention.
Embodiment 1
Prescription:
Preparation method is as follows:
Step one, take the former medicine 0.0387kg of coumatetralyl (amounting to into coumatetralyl is 0.0375kg), add absolute ethyl alcohol 0.9613kg wherein, be stirred to dissolving, obtain coumatetralyl solution (1kg);
Step 2, the 1kg coumatetralyl solution of gained is mixed with 0.5% Bromadiolone mother liquid of 1kg after, add 10kg bobbin oil and 90kg lubricating grease, stir, must kill mouse paste.
Using method: the paste that kills mouse is brushed on the pipeline at the place such as passageway, rat hole mouth, mouse road of often coming in and going out in muroid, floor, furniture, brush when metallic conduit, directly brush; Brush when floor or furniture, need first to be affixed on by adhesive waterproof tape on floor or furniture, the paste that then will kill mouse is brushed on adhesive waterproof tape; Use area and be coated with one piece by 10 square centimeters, the thickness that every block is smeared is about 0.5-2mm.
Embodiment 2
Prescription:
Preparation method is as follows:
Step one, take the former medicine 0.0387kg of coumatetralyl (amounting to into coumatetralyl is 0.0375kg), add absolute ethyl alcohol 0.9613kg wherein, be stirred to dissolving, obtain coumatetralyl solution (1kg);
Step 2, the 1kg coumatetralyl solution of gained is mixed with 0.5% Bromadiolone mother liquid of 2kg after, add 10kg bobbin oil and 88kg lubricating grease, stir, must kill mouse paste.
Using method: with embodiment 1.
Embodiment 3
Prescription:
Preparation method is as follows:
Step one, take the former medicine 0.0515kg of coumatetralyl (amounting to into coumatetralyl is 0.05kg), add absolute ethyl alcohol 0.9485kg wherein, be stirred to dissolving, obtain coumatetralyl solution (1kg);
Step 2, the 1kg coumatetralyl solution of gained is mixed with 0.5% Bromadiolone mother liquid of 1kg after, add 12kg bobbin oil and 95kg lubricating grease, stir, must kill mouse paste.
Using method: with embodiment 1.
Comparative example 1
Prescription:
This prescription is compared in embodiment 1: remove and kill mouse composition coumatetralyl, doubled by the consumption killing mouse composition 0.5% Bromadiolone mother liquid, all the other prescriptions are with embodiment 1.
Preparation method is as follows:
In 0.5% Bromadiolone mother liquid of 2kg, add 10kg bobbin oil and 90kg lubricating grease, stir, must kill mouse paste.
Using method: with embodiment 1.
Comparative example 2
Prescription:
This prescription is compared in embodiment 1: remove and kill mouse composition 0.5% Bromadiolone mother liquid, doubled by the consumption killing mouse composition coumatetralyl, all the other prescriptions are with embodiment 1.
Preparation method is as follows:
Step one, take the former medicine 0.0774kg of coumatetralyl (amounting to into coumatetralyl is 0.075kg), add absolute ethyl alcohol 0.9226kg wherein, be stirred to dissolving, obtain coumatetralyl solution (1kg);
Step 2, in the 1kg coumatetralyl solution of gained, add 10kg bobbin oil and 90kg lubricating grease, stir, must kill mouse paste.
Using method: with embodiment 1.
Comparative example 3
Prescription:
This prescription is compared in embodiment 1: the matrix components bobbin oil removing paste, its consumption is by lubricating grease polishing, consistent with embodiment 1 to ensure the content killing mouse composition.
Preparation method is as follows:
Step one, take the former medicine 0.0387kg of coumatetralyl (amounting to into coumatetralyl is 0.0375kg), add absolute ethyl alcohol 0.9613kg wherein, be stirred to dissolving, obtain coumatetralyl solution (1kg);
Step 2, the 1kg coumatetralyl solution of gained is mixed with 0.5% Bromadiolone mother liquid of 1kg after, add 100kg lubricating grease, stir, must kill mouse paste.
Using method: with embodiment 1.
Comparative example 4
Prescription:
This prescription is compared in embodiment 1: substituted by lubricating grease vaseline, and substituted by bobbin oil No. 20 machinery oil, all the other are with embodiment 1.
Preparation method is as follows:
Step one, take the former medicine 0.0387kg of coumatetralyl (amounting to into coumatetralyl is 0.0375kg), add absolute ethyl alcohol 0.9613kg wherein, be stirred to dissolving, obtain coumatetralyl solution (1kg);
Step 2, the 1kg coumatetralyl solution of gained is mixed with 0.5% Bromadiolone mother liquid of 1kg after, add No. 20 machinery oil and the 90kg vaseline of 10kg, stir, must kill mouse paste.
Using method: with embodiment 1.
Effect example 1
Each embodiment and each comparative example gained air-dry firm time of paste on metallic conduit, cement flooring, wood furniture that kill mouse compares;
Get the paste that kills mouse that each embodiment and comparative example are obtained respectively, is brushed on metallic conduit, cement flooring and wood furniture, brushing area 10 square metres, the thickness of the paste that kills mouse of brushing is 1mm;
Brushing mode
Metallic conduit: directly brush;
Cement flooring: first adhesive waterproof tape is pasted on cement flooring, the paste that then will kill mouse is brushed on adhesive waterproof tape;
Wood furniture: first adhesive waterproof tape is pasted on wood furniture, the paste that then will kill mouse is brushed on adhesive waterproof tape;
Observation kills mouse the air-dry sclerosis required time of paste, the results are shown in Table 1.
The time needed for the air-dry sclerosis of the paste that kills mouse that each embodiment of table 1 and comparative example obtain
From this table, data can draw, lubricating grease and shallow lake seed oil is adopted comparatively to adopt vaseline and No. 20 machinery oil as the matrix of paste and adopt separately lubricating grease as the matrix of paste, its air-dry sclerosis required time is longer, due to the prolongation of air-dry sclerosis required time, make the time lengthening of dosing interval, thus decrease dispensing number of times, it also avoid the change of the muroid living environment caused owing to frequently offeing medicine, avoid because muroid produces vigilance to the environment of frequency transformation and cause deratization rate to reduce.
Effect example 2
The comparison of the deratization effect of the paste that kills mouse that embodiment 1 and comparative example 1 ~ 4 obtain.
Select 5 villages of County of Hebei Province, village 1 is experiment one group, throws the mouse killing agent obtained by the embodiment of the present invention 1; Village 2 is contrast one group, throw comparative example 1 the medicament that is worth; Village 3 is contrast two groups, throws the medicament obtained by comparative example 2; Village 4 is contrast three groups, throws the medicament obtained by comparative example 3; Village 5 is contrast four groups, throws the medicament obtained by comparative example 4.
Dosing mode: adopt dosing time, the paste that kills mouse is brushed on the pipeline at the place such as passageway, rat hole mouth, mouse road of often coming in and going out in muroid, floor, furniture, use area and be coated with one piece by 10 square centimeters, adopt the brushing mode of being interrupted with combining continuously, the thickness that every block is smeared is about 1mm.
Kill mouse the investigation method of front and back rodent density: conventional pulvis method.
Experimental result: observe dead mouse situation every day, measures rodent density and calculates deratization effect after killing mouse 3 months, with killing mouse, front and back rodent density calculates correction deratization rate, the results are shown in Table 2.
The deratization effect of the paste that kills mouse that table 2 embodiment 1 and comparative example 1 ~ 4 obtain
Test one group Contrast one group Contrast two groups Contrast three groups Contrast four groups
Deratization rate % 99.11 84.32 88.60 76.47 73.21
As can be seen from data in table, (1) first generation anti-coagulant rodenticide coumatetralyl and the synergy of second generation anti-coagulant rodenticide Bromadiolone are used for killing mouse, and its deratization effect is significantly better than adopting separately first generation anti-coagulant rodenticide coumatetralyl or second generation anti-coagulant rodenticide Bromadiolone; (2) when killing mouse composition and being consistent, adopt lubricating grease and bobbin oil to be better than as the deratization effect of paste substrate and adopt separately lubricating grease as paste substrate, and adopt vaseline and No. 20 machinery oil as the deratization effect of paste substrate; Its reason is mainly and adopts vaseline and No. 20 machinery oil as paste substrate and only employing lubricating grease is as paste substrate, and the paste that kills mouse air-dry sclerosis required time is short, thus makes the too early air-dry sclerosis of paste that kills mouse, and have impact on deratization effect.
The above embodiment is only the preferred embodiments of the present invention, and and the feasible enforcement of non-invention exhaustive.For persons skilled in the art, to any apparent change done by it under the prerequisite not deviating from the principle of the invention and spirit, all should be contemplated as falling with within claims of the present invention.

Claims (3)

1. kill mouse a paste, it is characterized in that it is made up of following raw material:
2. one according to claim 1 kills mouse paste, it is characterized in that it is made up of following raw material:
3. kill mouse the preparation method of paste as claimed in claim 1 or 2, it is characterized in that it comprises the following steps:
Step one, take above-mentioned raw materials by weight after, in coumatetralyl, add absolute ethyl alcohol, be stirred to dissolving, obtain coumatetralyl solution;
Step 2, the coumatetralyl solution of gained is mixed with 0.5% Bromadiolone mother liquid after, add bobbin oil and lubricating grease, stir, must kill mouse paste.
CN201510678992.8A 2015-10-21 2015-10-21 One kind kills mouse paste and preparation method thereof Expired - Fee Related CN105379709B (en)

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Application Number Priority Date Filing Date Title
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CN105379709B CN105379709B (en) 2017-12-19

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109430302A (en) * 2018-12-11 2019-03-08 绵阳机场蓝天环保科技有限公司 It kills mouse and tracks cream and preparation method thereof
CN109662087A (en) * 2018-12-24 2019-04-23 云南省热带作物科学研究所 A kind of Queensland nut garden mouse killing method

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1090464A (en) * 1993-02-05 1994-08-10 戴兆明 Insecticide and rodenticide compound
CN1098935A (en) * 1994-05-23 1995-02-22 柴开源 A kind of relaxing muscles and tendons to promote blood circulation Chinese medicine composition and preparation method thereof
CN101822248A (en) * 2010-03-23 2010-09-08 卢军 Production and application of foot touch type anticoagulant powder raticide

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1092935A (en) * 1994-03-12 1994-10-05 邓建成 Rat-killing slurry

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1090464A (en) * 1993-02-05 1994-08-10 戴兆明 Insecticide and rodenticide compound
CN1098935A (en) * 1994-05-23 1995-02-22 柴开源 A kind of relaxing muscles and tendons to promote blood circulation Chinese medicine composition and preparation method thereof
CN101822248A (en) * 2010-03-23 2010-09-08 卢军 Production and application of foot touch type anticoagulant powder raticide

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109430302A (en) * 2018-12-11 2019-03-08 绵阳机场蓝天环保科技有限公司 It kills mouse and tracks cream and preparation method thereof
CN109662087A (en) * 2018-12-24 2019-04-23 云南省热带作物科学研究所 A kind of Queensland nut garden mouse killing method

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Granted publication date: 20171219