CN105362241B - A kind of preparation method of refined ginseng tablet - Google Patents
A kind of preparation method of refined ginseng tablet Download PDFInfo
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- CN105362241B CN105362241B CN201510878141.8A CN201510878141A CN105362241B CN 105362241 B CN105362241 B CN 105362241B CN 201510878141 A CN201510878141 A CN 201510878141A CN 105362241 B CN105362241 B CN 105362241B
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- 241000208340 Araliaceae Species 0.000 title claims abstract description 67
- 235000008434 ginseng Nutrition 0.000 title claims abstract description 67
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 title claims abstract description 66
- 235000003140 Panax quinquefolius Nutrition 0.000 title claims abstract description 66
- 238000002360 preparation method Methods 0.000 title claims abstract description 14
- 229930182494 ginsenoside Natural products 0.000 claims abstract description 20
- 229940089161 ginsenoside Drugs 0.000 claims abstract description 18
- 239000002994 raw material Substances 0.000 claims description 25
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 14
- 238000001035 drying Methods 0.000 claims description 14
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 14
- 239000000463 material Substances 0.000 claims description 10
- 239000000047 product Substances 0.000 claims description 9
- 239000000706 filtrate Substances 0.000 claims description 8
- 230000008030 elimination Effects 0.000 claims description 7
- 238000003379 elimination reaction Methods 0.000 claims description 7
- 235000019441 ethanol Nutrition 0.000 claims description 7
- 239000012535 impurity Substances 0.000 claims description 7
- 238000002156 mixing Methods 0.000 claims description 7
- 239000002245 particle Substances 0.000 claims description 7
- 238000001914 filtration Methods 0.000 claims description 6
- 238000004806 packaging method and process Methods 0.000 claims description 3
- 239000012141 concentrate Substances 0.000 claims description 2
- 239000000843 powder Substances 0.000 claims description 2
- 238000001514 detection method Methods 0.000 claims 1
- 238000000034 method Methods 0.000 abstract description 11
- 230000000694 effects Effects 0.000 abstract description 9
- 239000001397 quillaja saponaria molina bark Substances 0.000 abstract description 9
- 229930182490 saponin Natural products 0.000 abstract description 9
- 150000007949 saponins Chemical group 0.000 abstract description 9
- 238000010025 steaming Methods 0.000 abstract description 7
- 238000010521 absorption reaction Methods 0.000 abstract description 2
- 235000013305 food Nutrition 0.000 abstract description 2
- 229930182478 glucoside Natural products 0.000 abstract description 2
- 239000004615 ingredient Substances 0.000 abstract description 2
- 125000004395 glucoside group Chemical group 0.000 abstract 1
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 description 10
- 238000012856 packing Methods 0.000 description 8
- 229920002472 Starch Polymers 0.000 description 5
- 238000007689 inspection Methods 0.000 description 5
- 239000007788 liquid Substances 0.000 description 5
- 235000019359 magnesium stearate Nutrition 0.000 description 5
- 239000008107 starch Substances 0.000 description 5
- 235000019698 starch Nutrition 0.000 description 5
- 235000002789 Panax ginseng Nutrition 0.000 description 3
- 239000002671 adjuvant Substances 0.000 description 3
- 230000001093 anti-cancer Effects 0.000 description 3
- 229940079593 drug Drugs 0.000 description 3
- 239000003814 drug Substances 0.000 description 3
- 230000008595 infiltration Effects 0.000 description 3
- 238000001764 infiltration Methods 0.000 description 3
- 231100000331 toxic Toxicity 0.000 description 3
- 230000002588 toxic effect Effects 0.000 description 3
- 239000004480 active ingredient Substances 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 239000000470 constituent Substances 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 229940126680 traditional chinese medicines Drugs 0.000 description 2
- RWXIFXNRCLMQCD-JBVRGBGGSA-N (20S)-ginsenoside Rg3 Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1O[C@H]1CC[C@]2(C)[C@H]3C[C@@H](O)[C@H]4[C@@]([C@@]3(CC[C@H]2C1(C)C)C)(C)CC[C@@H]4[C@@](C)(O)CCC=C(C)C)[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O RWXIFXNRCLMQCD-JBVRGBGGSA-N 0.000 description 1
- 239000003390 Chinese drug Substances 0.000 description 1
- 235000002791 Panax Nutrition 0.000 description 1
- 241000208343 Panax Species 0.000 description 1
- 240000004371 Panax ginseng Species 0.000 description 1
- 238000006114 decarboxylation reaction Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000018044 dehydration Effects 0.000 description 1
- 238000006297 dehydration reaction Methods 0.000 description 1
- 150000008131 glucosides Chemical group 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 125000000346 malonyl group Chemical group C(CC(=O)*)(=O)* 0.000 description 1
- 239000013049 sediment Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000002352 surface water Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/10—Preparation or pretreatment of starting material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Alternative & Traditional Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicinal Preparation (AREA)
Abstract
The present invention relates to a kind of ginseng food making method, total Ginsenosides Content higher especially in preparation, the preparation method of a kind of refined ginseng tablet that the secondary saponin content of ginseng dramatically increases.The process of steaming sets three temperature spots, and control time carries out.After testing, ginsenoside Rg3Content is 0.45% 0.60%.Compared with other ginseng products, more rare saponin(es and secondary glucoside can be generated, particularly the representative are effect ingredient ginsenoside Rgs3Content significantly increases, and effect is more notable.This tablet has the characteristics that accurate dosage, stable quality, convenient to take, absorption is fast, utilization rate is high.
Description
Technical field
The present invention relates to a kind of ginseng food making method, total Ginsenosides Content higher especially in preparation, ginseng
The preparation method of a kind of refined ginseng tablet that raw saponin content dramatically increases.
Background technology
Ginseng（Panax ginsengC. A. Mey）It is the dry root of Araliaceae ginseng, principle active component
It is ginsenoside, there is high medical value and health-care effect, especially has effects that enhance body immunity.Therefore, it sends out
The form of Chinese drug of Zhan Xin is just particularly important.
Invention content
The technical problems to be solved by the invention are temperature adjustment to be controlled to steam by long-time, overcome ginsenoside Rg3Etc. having
The defects of effective component content is low, provide a kind of active ingredient increase, treatment significant in efficacy, of low cost, toxic side effect is small and
The preparation method of anticancer adjuvant drug.
Technical solution is：The preparation method of refined ginseng tablet：（1）Fresh ginseng is cleaned, after impurity elimination, dries surface water
Point, it is steamed, the process of steaming sets three temperature spots, and control time carries out (temperature being gradually increased, the time gradually increases, and prevents
Only ginseng carbonizes, and is conducive to ginsenoside Rg3Etc. active ingredients fully convert, make ginsenoside Rg3Active constituent contents is waited to increase
Add).Temperature is 60-75 DEG C, is steamed 2-6 hours, and temperature is 75-90 DEG C, is steamed 3-8 hours, and temperature is 90-100 DEG C, is steamed
It 3-7 hours, steams ginseng and is placed in drying box, dry, temperature is set as 40-80 DEG C, until raw material ginseng water content 15% is hereinafter, take
Go out spare.（2）Ginseng raw material is infiltrated, segment（10-30mm）, by solid-liquid ratio（Raw material：Water）1:6-1:16, decoction 2-3 times, often
2-3 hours secondary, filtration, merging filtrate concentrates, and refined ginseng tablet's raw extract is made in microwave drying.（3）Raw material is extracted
Object dry, pulverize, and crosses 60-120 mesh sieve, adds in appropriate amount of auxiliary materials（Or auxiliary material is added in, such as starch, magnesium stearate）, add in appropriate
After mixing, particle is made in 50%-85% ethyl alcohol, crosses 16-20 mesh sieve, and tabletting is coated, and packing, outer packing, inspection is qualified, obtains into
Product.After testing, ginsenoside Rg3Content is 0.45%-0.60%.Tablet meets《Chinese Pharmacopoeia》It is advised under version tablet items in 2015
It is fixed.
The preparation method of refined ginseng tablet, its step are as follows：Fresh ginseng is cleaned, after impurity elimination, dries surface moisture, into
Three temperature spots of row steam, and temperature is 65 DEG C, is steamed 4 hours, and temperature is 80 DEG C, is steamed 6 hours, and temperature is 95 DEG C, and it is small to steam 6
When；It steams ginseng to be placed in drying box, dry, temperature is set as 60 DEG C, until raw material ginseng water content 15% is hereinafter, take out spare；It will
Ginseng raw material infiltrates, segment, by raw material：Water=1:10, it decocts 2 times, 3 hours every time, filtration, merging filtrate concentrated, and microwave is done
It is dry, refined ginseng tablet's raw extract is made；Raw extract dry, pulverize, sieve with 100 mesh sieve, add in appropriate amount of auxiliary materials（It forms sediment
Powder, magnesium stearate etc.）, 75% ethyl alcohol is added in, after mixing, particle is made, crosses 16 mesh sieve, tabletting is coated, and packaging obtains finished product；Inspection
It surveys, refines ginseng tablet ginsenoside Rg3Content 0.54%.
Advantage is：1st, it is the dry root and root that the control temperature adjustment of fresh ginseng through a long time steams to refine ginseng tablet material
Stem.Compared with other ginseng products, more rare saponin(es and secondary glucoside can be generated, particularly the representative are effect ingredients
Ginsenoside Rg3Content significantly increases, and effect is more notable, provide it is a kind of it is significant in efficacy, of low cost, toxic side effect is small controls
Treatment and the preparation method of anticancer adjuvant drug.Ginseng tablet material is made by the process such as steaming, drying in fresh ginseng, due to
Heat treatment can convert Chemical Constituents of Panax Ginseng, in process, starch in ginseng also some be broken down into paste
The fracture of ester bond and glycosidic bond, generation decarboxylation, desugar catabolite, macromolecular can occur for essence, the saponin component in red ginseng
Amount, highly polar saponin(e are converted into corresponding small-molecular-weight, low polarity saponin, or C-20 native configurations change, raw
Into certain distinctive ginsenoside Rgs3, and steaming in process and the process conditions such as dry and also provided for reaction and fill
The external condition of foot steams and saponin(e in red ginseng is promoted to react, and drying makes its dehydration conversion ginsenoside Rg3, panoxadiol
Type (panaxadio-l type) malonyl ginsenoside is mainly hydrolyzed and is converted into ginsenoside Rg3.2nd, this tablet
Have the characteristics that accurate dosage, stable quality, convenient to take, absorption is fast, utilization rate is high.3rd, this tablet ginsenoside Rg3Content
For 0.45%-0.60%.
Specific embodiment
Form by the following examples is described in further detail, but should not be by this above of present invention again
The range for being interpreted as the above-mentioned theme of the present invention is only limitted to following embodiment, all technologies realized based on the above of the present invention
It all belongs to the scope of the present invention.
Embodiment 1
Fresh ginseng is cleaned, after impurity elimination, dries surface moisture, is steamed, the process of steaming sets three temperature spots, during control
Between carry out.Temperature is 65 DEG C, is steamed 3 hours, and temperature is 80 DEG C, is steamed 5 hours, and temperature is 90 DEG C, steams 4 hours, steams people
Ginseng is placed in drying box, dry, and temperature is set as 50 DEG C, until raw material ginseng water content 15% is hereinafter, take out spare.By ginseng raw material
Infiltration, segment（15mm）, by solid-liquid ratio（Raw material：Water）1:8, it decocts 3 times, 2 hours every time, filtration, merging filtrate concentrated, micro-
Wave is dried, and refined ginseng tablet's raw extract is made.Raw extract dry, pulverize, cross 80 mesh sieve, add in appropriate amount of auxiliary materials
（Starch, magnesium stearate etc.）, appropriate 70% ethyl alcohol is added in, after mixing, particle is made, crosses 16 mesh sieve, crosses 16 mesh sieve, tabletting, packet
Clothing, packing, outer packing, inspection is qualified, obtains finished product.After testing, ginsenoside Rg3Content is 0.51%.Tablet meets《Middle traditional Chinese medicines
Allusion quotation》It is provided under version tablet items in 2015.
Embodiment 2
Fresh ginseng is cleaned, after impurity elimination, dries surface moisture, is steamed, the process of steaming sets three temperature spots, during control
Between carry out.Temperature is 70 DEG C, is steamed 4 hours, and temperature is 85 DEG C, is steamed 6 hours, and temperature is 95 DEG C, steams 5 hours, steams people
Ginseng is placed in drying box, dry, and temperature is set as 60 DEG C, until raw material ginseng water content 15% is hereinafter, take out spare.By ginseng raw material
Infiltration, segment（20mm）, by solid-liquid ratio（Raw material：Water）1:10, it decocts 2 times, 3 hours every time, filtration, merging filtrate concentrated, micro-
Wave is dried, and refined ginseng tablet's raw extract is made.Fresh ginseng to be cleaned, the first stage steams 4 hours, and temperature is 70 DEG C, the
Two-stage steams 4 hours, and temperature is 85 DEG C, and the phase III steams 3 hours, and temperature is 95 DEG C, is placed in drying box, dry, temperature
Degree is set as 60 DEG C, and refined ginseng tablet raw material is made, spare.Weigh refined ginseng tablet raw material 1000g, solid-liquid ratio 1:10, decoct 2
Secondary, 3 hours every time, merging filtrate concentrated, and refined ginseng tablet's raw extract is made in microwave drying,（Repetition is removed）By raw material
Extract dry, pulverize, and 100 mesh sieve adds in appropriate amount of auxiliary materials（Starch, magnesium stearate etc.）, appropriate 75% ethyl alcohol is added in, after mixing,
Particle is made, crosses 16 mesh sieve, crosses 16 mesh sieve, tabletting is coated, and packing, outer packing, inspection is qualified, obtains finished product.After testing, ginseng
Saponin(e Rg3Content is 0.53%.Tablet meets《Chinese Pharmacopoeia》It is provided under version tablet items in 2015.
Embodiment 3
Fresh ginseng is cleaned, after impurity elimination, dries surface moisture, is steamed, the process of steaming sets three temperature spots, during control
Between carry out.Temperature is 75 DEG C, is steamed 3 hours, and temperature is 85 DEG C, is steamed 7 hours, and temperature is 100 DEG C, steams 7 hours, steams people
Ginseng is placed in drying box, dry, and temperature is set as 65 DEG C, until raw material ginseng water content 15% is hereinafter, take out spare.By ginseng raw material
Infiltration, segment（25mm）, by solid-liquid ratio（Raw material：Water）1:15, it decocts 3 times, 3 hours every time, filtration, merging filtrate concentrated, micro-
Wave is dried, and refined ginseng tablet's raw extract is made.Raw extract dry, pulverize, cross 120 mesh sieve, add in appropriate amount of auxiliary materials
（Starch, magnesium stearate etc.）, appropriate 75% ethyl alcohol is added in, after mixing, particle is made, crosses 16 mesh sieve, crosses 16 mesh sieve, tabletting, packet
Clothing, packing, outer packing, inspection is qualified, obtains finished product.After testing, ginsenoside Rg3Content is 0.54%.Tablet meets《Middle traditional Chinese medicines
Allusion quotation》It is provided under version tablet items in 2015.
This invention ginseng sapoglycoside Rg 3 content increases, provide it is a kind of it is significant in efficacy, of low cost, toxic side effect is small controls
Treatment and the preparation method of anticancer adjuvant drug.
Embodiment 4
It is detected through Ginseng In Jilin Province inspection center, refines ginseng tablet ginsenoside Rg3Content 0.51-0.54%.
Claims (3)
1. a kind of preparation method of refined ginseng tablet, it is characterised in that step is as follows：
（1）Fresh ginseng is cleaned, surface moisture is dried after impurity elimination, carries out three temperature spots and steams, temperature is that temperature is 60-75
DEG C, it steams 2-6 hours, temperature is 75-90 DEG C, is steamed 3-8 hours, and temperature is 90-100 DEG C, is steamed 3-7 hours；Steam ginseng
It is placed in drying box, dry, 40-80 DEG C of temperature, until raw material ginseng water content 15% is hereinafter, take out spare；
（2）Ginseng raw material is infiltrated, segment, by raw material：Water=1:6-1:16, it decocts 2-3 times, it is 2-3 hours each, it filters, closes
And refined ginseng tablet's raw extract is made in filtrate, concentration, microwave drying；
（3）Raw extract dry, pulverize, cross 60-120 mesh sieve, add in auxiliary material, add in 50%-85% ethyl alcohol, after mixing, system
Into particle, 16-20 mesh sieve is crossed, tabletting is coated, and packaging obtains finished product.
2. the preparation method of refined ginseng tablet as described in claim 1, it is characterised in that step is as follows：Fresh ginseng is clear
It washes, after impurity elimination, dries surface moisture, carry out three temperature spots and steam, temperature is 65 DEG C, is steamed 4 hours, and temperature is 80 DEG C, is steamed
System 6 hours, temperature are 95 DEG C, are steamed 6 hours；It steams ginseng to be placed in drying box, dry, temperature is set as 60 DEG C, until raw material people
Join water content 15% hereinafter, taking out spare；Ginseng raw material is infiltrated, segment, by raw material：Water=1:10, it decocts 2 times, 3 is small every time
When, filtration, merging filtrate concentrates, and refined ginseng tablet's raw extract is made in microwave drying；Raw extract is dried, powder
It is broken, it sieves with 100 mesh sieve, adds in auxiliary material, add in 75% ethyl alcohol, after mixing, particle is made, cross 16 mesh sieve, tabletting is coated, and packaging obtains
Finished product；Detection refines ginseng tablet ginsenoside Rg3Content 0.54%.
3. the preparation method of refined ginseng tablet as described in claim 1, it is characterised in that finished product ginsenoside Rg3Contain
It measures as 0.45%-0.60%.
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| CN107402276A (en) * | 2016-05-21 | 2017-11-28 | 广州今典精方药业有限公司 | The quality standard and manufacturing process of the American Ginseng qualitative, quantitative prepared slices of Chinese crude drugs |
| CN106071901A (en) * | 2016-06-06 | 2016-11-09 | 马晓磊 | A kind of Radix Ginseng health preserving jerky and preparation method thereof |
| CN108066603A (en) * | 2016-11-11 | 2018-05-25 | 成都体九生物科技有限公司 | A kind of concocting method of polyghace-seche ginseng |
| CN110721171A (en) * | 2019-10-30 | 2020-01-24 | 安徽九华华源药业有限公司 | Improved vibration source sheet and preparation method thereof |
| CN112274545A (en) * | 2020-11-17 | 2021-01-29 | 刘伟德 | Production process of red ginseng extract tablet |
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| CN100484519C (en) * | 2003-08-29 | 2009-05-06 | 雅安三九药业有限公司 | Ginseng and aconite tablet for injection use for treating qi vacuity and yang desertion and its preparation method |
| CN1272026C (en) * | 2004-08-20 | 2006-08-30 | 张正生 | Medicinal composition for treating cardiocerebral vasculr disease and its preparing method |
| CN102755362B (en) * | 2011-04-28 | 2015-03-04 | 天津天士力之骄药业有限公司 | Red ginseng processing method |
| CN103053897B (en) * | 2011-10-20 | 2016-09-28 | 北京以岭药业有限公司 | A kind of ginseng polysaccharide chewable tablet and preparation method thereof |
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| CN105533745A (en) * | 2015-12-31 | 2016-05-04 | 吉林紫鑫药业股份有限公司 | Ginseng and honeysuckle tablets and production method thereof |
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