CN105360141B - Purposes of the compound Cniforin B as agricultural bacteriocide - Google Patents
Purposes of the compound Cniforin B as agricultural bacteriocide Download PDFInfo
- Publication number
- CN105360141B CN105360141B CN201510837837.6A CN201510837837A CN105360141B CN 105360141 B CN105360141 B CN 105360141B CN 201510837837 A CN201510837837 A CN 201510837837A CN 105360141 B CN105360141 B CN 105360141B
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- Prior art keywords
- cniforin
- compound
- agricultural
- agricultural chemicals
- active component
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Classifications
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N41/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a sulfur atom bound to a hetero atom
- A01N41/02—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a sulfur atom bound to a hetero atom containing a sulfur-to-oxygen double bond
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/64—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with three nitrogen atoms as the only ring hetero atoms
- A01N43/647—Triazoles; Hydrogenated triazoles
- A01N43/653—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
Abstract
The invention discloses a kind of natural purposes of the angle-furocoumarins compound Cniforin B as agricultural bacteriocide.Compound Cniforin B are used to prevent and treat agricultural fungal evil as bactericide, can effectively prevent and treat the corps diseases such as sclerotinia sclerotiorum, grey mould fruit rot of strawberry, wheat scab, pepper anthracnose, early blight of tomato.Native compound Cniforin B have that prevention effect is good as agricultural bacteriocide made of active component, broad spectrum activity and low toxicity, noresidue, pollution-free, non-harmful feature, are particularly conducive to environmental protection.
Description
Technical field
The invention belongs to agricultural technology field, and in particular to a kind of natural angle-furocoumarins compound Cniforin B
The purposes of agricultural bacteriocide is prepared as active component.
Background technology
The disease of crops due to easily being discovered in time unlike insect and weeds by people, so often resulting in preventing and treating
On ignorance and difficulty, thus its harm just it is even more serious.It is reported that whole world list is the plant disease as caused by disease fungus
Just up to 10,000 kinds, caused loss accounts for the 10%~30% of crop year total losses.If virus, bacterium and nematode etc. are drawn
Including the plant disease risen is also calculated, its loss is just more considerable.
In order to meet people's needs growing to grain and other living materials, it has to use chemicals to protect
Crop is not attacked by harmful organism, and wherein bactericide plays an important role.Natural products with agricultural bactericidal activity, typically
Easily it is absorbed by plants and conducts, it is small to phyto toxicity or without poisoning, therefore by attention.
Compound English name Cniforin B, molecular formula：C23H26O7, molecular weight 414.3591, planted from Umbelliferae
In thing, molecular structure：
Compound Cniforin B, are dissolved in the organic solvents such as methanol, ethanol, acetone, ethyl acetate, chloroform.To its activity
Effect study is less, so far without as agricultural bacteriocide in the pertinent literature or report agriculturally applied.
The content of the invention
The purpose of the present invention is to explore compound Cniforin B to prepare the application of agricultural bacteriocide as active component.
The present invention proves that compound Cniforin B sterilize as the agricultural that active component is prepared by numerous studies
Agent has excellent bactericidal activity, can be applicable to the fungal disease prevented and treated on various crops, such as：Sclerotinia sclerotiorum, strawberry
Gray mold, wheat scab, pepper anthracnose, early blight of tomato etc..
Compound Cniforin B are to isolate and purify to obtain from natural plants, can also be obtained by chemical synthesis process.
Any one formulation that compound Cniforin B are configured to allow on agricultural chemicals as active component and insecticides adjuvant, excipients.
It can also be mixed and made into any one formulation allowed on agricultural chemicals with insecticides adjuvant, excipients with other agriculture chemical compoundings.It is described
Formulation can be missible oil, suspending agent, aqueous emulsion, wettable powder, microemulsion or water dispersion granule etc..Auxiliary agent used can
With using calcium dodecyl benzene sulfonate, pyrrolidones, polyoxyethylene polyoxy propylene block compound, NPE
Can be cyclohexanone, solvent naphtha, solvent naphtha, water, propane diols, deionized water etc. Deng, excipient.Compounding other agricultural chemicals used can be
Organic bactericide class, such as triazole bactericidal agent Triadimenol；Botanical fungicide, such as allicin.
Beneficial effects of the present invention compared with the prior art：For compound Cniforin B as bactericide, antimicrobial spectrum is wide, holds
The effect phase is grown, and is agriculturally preferable bactericide.Learned to farm medicine phases ratio with vague generalization, it is right due to the extract from natural plants
There is low toxicity, noresidue, pollution-free, non-harmful feature, more favorable environment in industrial crops such as various grains, melon fruits and vegetables
Protection.
Embodiment
Effect of the present invention is described further below by way of embodiment：
Embodiment 1：Preventing and treatings of the compound Cniforin B to agricultural disease
Strains tested sclerotinite (Sclerotioia selerotiorum) is isolated from sclerotinia sclerotiorum bacterial strain；It is vertical
Withered silk kernel fungus (Thanatephorus cucumeris) separate from rice sheath blight disease disease leaf；Botrytis cinerea (Botrytis
), cinerea also known as the pathogen of Botrytis cinerea is isolated from grey mould fruit rot of strawberry；Fusarium graminearum (Fusarium.graminearm)
It is isolated from wheat scab fringe；Rhizoctonia cerealis（Rhizoctonia solani）Separated from wheat sharp eyespot leaf
Arrive；Phytophthora capsici (phytophthora capsici) separates from capsicum diseased plant；Capsicum thorn disk spore [Colletotrichum
Capsici (syd.) Butl.] it is isolated from pepper anthracnose fruit；Sporulation（Alternaria
solani.）It is isolated from early blight of tomato leaf.
Test compound Cniforin B, it is dissolved in methanol and 1000 μ g/mL mother liquors is made, 4 DEG C save backup.PDA is trained
Support base:200g peeled potatoes are cut into block, after boiling 10min, take juice, add 20g agar, be heated to melting, add 20g
Glucose, 1000mL is settled to water.
Determined using suppression of the mycelial growth rate determination method to mycelial growth, preculture supplies examination bacterium from PDA plate
Edge, which is beaten, takes bacterium dish (diameter 5mm), and reagent agent mother liquor is uniformly mixed with culture medium, makes the reagent agent ultimate density be
30ppm, mixed liquor are poured into a diameter of 9cm sterilizing culture dish and flat board are made, and a bacterium dish are inoculated with per ware, mycelia is face-up, often
Processing is repeated 3 times.When 25 DEG C of cultures to control bacterium colony is covered with culture dish more than 2/3rds, crossing method measurement bacterium colony increases
Diameter.Growth inhibition ratio is calculated by colony diameter average value (mm).
Using Osthole Osthol as positive reference substance, compound Cniforin B can be effectively as can be seen from the results
Sclerotinia sclerotiorum, grey mould fruit rot of strawberry, wheat scab, pepper anthracnose, early blight of tomato etc. are prevented and treated, concentration 30ppm is several to this
Kind disease suppression rate is respectively 62.81%, 46.76%, 50.4%, 43.2%, 42.91%, and specific experiment the results are shown in Table 1；Pass through experiment
The remarkable result of agricultural chemicals of the present invention is fully demonstrated, especially to fungal disease sclerotinia sclerotiorum, grey mould fruit rot of strawberry, gibberella saubinetii
Disease, pepper anthracnose, early blight of tomato etc..
The compound Cniforin B of table 1（Concentration is 30ppm）To the bacteriostasis rate of agricultural disease
Embodiment 2：
The customary adjuvant such as Weigh Compound Cniforin B and lignin, diatomite according to common process, be made effectively into
Divide the wettable powder that concentration is 2%.
Embodiment 3：
Weigh Compound Cniforin B and calcium dodecyl benzene sulfonate, phenethyl phenol polyethenoxy ether, solvent naphtha etc. are normal
Auxiliary material is advised according to common process, the missible oil that effective constituent concentration is 2% is made.
Embodiment 4：
The customary adjuvant such as Weigh Compound Cniforin B and wooden sodium sulfonate, kaolin is formed with according to common process
Imitate the water dispersible granules that constituent concentration is 2%.
Embodiment 5：
Weigh Compound Cniforin B are with the customary adjuvant such as solvent naphtha, pyrrolidones, xanthans according to common process, system
Into the aqueous emulsion that active ingredient concentration is 1%.
Embodiment 6：
The customary adjuvant such as Weigh Compound Cniforin B and calcium dodecyl benzene sulfonate, pyrrolidones is according to conventional work
Skill, the microemulsion that effective constituent concentration is 1% is made.
Embodiment 7：
According to weight than 1：5 ratio Weigh Compound Cniforin B and Triadimenol, it is yellow with solvent naphtha, pyrrolidones
The aqueous emulsion that effective constituent concentration is 5% is made according to common process in the customary adjuvants such as virgin rubber.
Embodiment 8：
According to weight than 6：1 ratio Weigh Compound Cniforin B and allicin, it is yellow with solvent naphtha, pyrrolidones
The aqueous emulsion that effective constituent concentration is 5% is made according to common process in the customary adjuvants such as virgin rubber.
Claims (3)
1. compound Cniforin B as active component prepare preventing and treating sclerotinia sclerotiorum, grey mould fruit rot of strawberry, wheat scab,
Pepper anthracnose, early blight of tomato agricultural bacteriocide in purposes.
2. purposes according to claim 1, it is characterised in that compound Cniforin B help as active component and agricultural chemicals
Agent, excipients are configured to any one formulation allowed on agricultural chemicals；Or compound Cniforin B are as active component and its
His agricultural chemicals and insecticides adjuvant, excipients are configured to any one formulation allowed on agricultural chemicals.
3. purposes according to claim 2, it is characterised in that described formulation is missible oil, suspending agent, aqueous emulsion, wettable
Pulvis, microemulsion or water dispersion granule；Other described agricultural chemicals are that triazole bactericidal agent Triadimenol or botanical fungicide are big
Allicin.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510837837.6A CN105360141B (en) | 2015-11-26 | 2015-11-26 | Purposes of the compound Cniforin B as agricultural bacteriocide |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510837837.6A CN105360141B (en) | 2015-11-26 | 2015-11-26 | Purposes of the compound Cniforin B as agricultural bacteriocide |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN105360141A CN105360141A (en) | 2016-03-02 |
| CN105360141B true CN105360141B (en) | 2017-12-15 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510837837.6A Active CN105360141B (en) | 2015-11-26 | 2015-11-26 | Purposes of the compound Cniforin B as agricultural bacteriocide |
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Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1869032A (en) * | 2005-05-26 | 2006-11-29 | 沈阳化工研究院 | Coumarin kind compound and its preparation and application |
| CN102177162B (en) * | 2008-10-21 | 2015-02-11 | 花王株式会社 | NFAT signal inhibitor and hair-growing agent |
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- 2015-11-26 CN CN201510837837.6A patent/CN105360141B/en active Active
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| CN105360141A (en) | 2016-03-02 |
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