CN105343775A - Medicine for treating alopecia - Google Patents

Medicine for treating alopecia Download PDF

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CN105343775A
CN105343775A CN201510837396.XA CN201510837396A CN105343775A CN 105343775 A CN105343775 A CN 105343775A CN 201510837396 A CN201510837396 A CN 201510837396A CN 105343775 A CN105343775 A CN 105343775A
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parts
radix
fructus
medicine
sieb
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劳冠阳
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    • A—HUMAN NECESSITIES
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
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Abstract

The invention provides medicine for treating alopecia. The medicine is prepared by, by weight, 20-30 parts of fructus ligustri lucidi, 20-30 parts of poria cocos, 20-30 parts of angelica sinensis, 20-30 parts of semen sesami nigrum, 20-30 parts of radix tinosporae, 10-20 parts of herba leonuri, 10-20 parts of radix codonopsis, 10-20 parts of radix ophiopogonis, 10-20 parts of semen euryales, 10-20 parts of pig gall bladder, 10-20 parts of loranthus parasiticus, 1-10 parts of Raphiolepis indica, 1-10 parts of radix bupleuri, 1-10 parts of Terminalia chebula Retz., 1-10 parts of fructus gardeniae, 1-10 parts of fructus arctii, 1-10 parts of polygonum multiflorum, 0.1-1 part of fructus lycii, 0.1-1 part of radix angelicae dahuricae, 0.1-1 part of oroxylum indicum, 0.1-1 part of sapindus mukorossi and 0.1-1 part of curcuma zedoary. The medicine for treating the alopecia is cheap, good in curative effect and small in toxic and side effects.

Description

The medicine of hair growth
Technical field
The present invention relates to a kind of medicine of hair growth, belong to technical field of Chinese medicines.
Background technology
Alopecia, especially pathologic alopecia, refer to hair exception or excessive coming off, its reason is a lot, mainly contains following several: androgenetic alopecia, nervous alopecia and endocrine alopecia.Therapeutic Method is mainly to be wiped outward with minoxidil in minoxidil tincture, and Finasteroid oral, also can adopt hair of scalp Implant.But use minoxidil in minoxidil tincture and finasteride to be hormone medicine, long-time treatment can produce great side effect, and curative effect also can be worse and worse; Hair of scalp Implant is then expensive, is not suitable for promoting.
Summary of the invention
The technical problem to be solved in the present invention is: the medicine providing the hair growth that a kind of low price, therapeutic effect are good, toxic and side effects is little.
For solving the problems of the technologies described above, the present invention by the following technical solutions:
The medicine of hair growth, obtained by the raw material of following weight parts: Fructus Ligustri Lucidi 20 ~ 30 parts, 20 ~ 30 parts, Poria, Radix Angelicae Sinensis 20 ~ 30 parts, Semen Sesami Nigrum 20 ~ 30 parts, Radix Tinosporae 20 ~ 30 parts, Herba Leonuri 10 ~ 20 parts, Radix Codonopsis 10 ~ 20 parts, Radix Ophiopogonis 10 ~ 20 parts, Semen Euryales 10 ~ 20 parts, Fel Sus domestica 10 ~ 20 parts, Herba Taxilli 10 ~ 20 parts, 1 ~ 10 part, wheel prunus mume (sieb.) sieb.et zucc., Radix Bupleuri 1 ~ 10 part, Fructus chebulae immaturus 1 ~ 10 part, Fructus Gardeniae 1 ~ 10 part, Fructus Arctii 1 ~ 10 part, Radix Polygoni Multiflori 1 ~ 10 part, Fructus Lycii 0.1 ~ 1 part, the Radix Angelicae Dahuricae 0.1 ~ 1 part, Semen Oroxyli 0.1 ~ 1 part, Fructus Sapindi Mukouossi 0.1 ~ 1 part, Rhizoma Curcumae 0.1 ~ 1 part.
As preferably, here provide a concrete formula, the weight portion of described raw material is: Fructus Ligustri Lucidi 20 parts, 25 parts, Poria, Radix Angelicae Sinensis 30 parts, Semen Sesami Nigrum 20 parts, Radix Tinosporae 25 parts, Herba Leonuri 20 parts, Radix Codonopsis 10 parts, Radix Ophiopogonis 15 parts, Semen Euryales 20 parts, Fel Sus domestica 10 parts, Herba Taxilli 15 parts, 10 parts, wheel prunus mume (sieb.) sieb.et zucc., Radix Bupleuri 1 part, Fructus chebulae immaturus 5 parts, Fructus Gardeniae 10 parts, Fructus Arctii 1 part, Radix Polygoni Multiflori 5 parts, Fructus Lycii 1 part, the Radix Angelicae Dahuricae 0.1 part, Semen Oroxyli 0.5 part, Fructus Sapindi Mukouossi 1 part, Rhizoma Curcumae 0.1 part.
As preferably, here provide second concrete formula, the weight portion of described raw material is: Fructus Ligustri Lucidi 25 parts, 30 parts, Poria, Radix Angelicae Sinensis 20 parts, Semen Sesami Nigrum 25 parts, Radix Tinosporae 30 parts, Herba Leonuri 10 parts, Radix Codonopsis 15 parts, Radix Ophiopogonis 20 parts, Semen Euryales 10 parts, Fel Sus domestica 15 parts, Herba Taxilli 20 parts, 1 part, wheel prunus mume (sieb.) sieb.et zucc., Radix Bupleuri 5 parts, Fructus chebulae immaturus 10 parts, Fructus Gardeniae 1 part, Fructus Arctii 5 parts, Radix Polygoni Multiflori 10 parts, Fructus Lycii 0.1 part, the Radix Angelicae Dahuricae 0.5 part, Semen Oroxyli 1 part, Fructus Sapindi Mukouossi 0.1 part, Rhizoma Curcumae 0.5 part.
As preferably, here provide the 3rd concrete formula, the weight portion of described raw material is: Fructus Ligustri Lucidi 30 parts, 20 parts, Poria, Radix Angelicae Sinensis 25 parts, Semen Sesami Nigrum 30 parts, Radix Tinosporae 20 parts, Herba Leonuri 15 parts, Radix Codonopsis 20 parts, Radix Ophiopogonis 10 parts, Semen Euryales 15 parts, Fel Sus domestica 20 parts, Herba Taxilli 10 parts, 5 parts, wheel prunus mume (sieb.) sieb.et zucc., Radix Bupleuri 10 parts, Fructus chebulae immaturus 1 part, Fructus Gardeniae 5 parts, Fructus Arctii 10 parts, Radix Polygoni Multiflori 1 part, Fructus Lycii 0.5 part, the Radix Angelicae Dahuricae 1 part, Semen Oroxyli 0.1 part, Fructus Sapindi Mukouossi 0.5 part, Rhizoma Curcumae 1 part.
The present invention also provides the preparation method of said medicine, its step the following is: be alcohol-pickled 0.5 ~ 2 hour of 30% ~ 60% by raw material volumetric concentration, taking-up water rinses, the hot pot being placed in 180 ~ 220 DEG C stir-fries 20 ~ 30 minutes, take out and rinse with water again, then be dipped in the water of raw material weight 3 ~ 10 times, after being heated to boiling, decoct 1 ~ 3 hour under slight boiling condition, filter, filtrate is concentrated into 30% ~ 40% of its volume, adds the modified starch of concentrated solution weight 1% ~ 3%, after spraying dry, gained powder is this medicine.
The using method of this medicine is: added in warm water by medicine and take after mixing it with water, and each consumption is 5 ~ 10 grams, within one day, takes 2 ~ 3 times.
The invention has the beneficial effects as follows: raw material of the present invention is conventional Chinese herbal medicine, wide material sources, low price; Pharmaceutical formulation is scientific and reasonable, synergism between each component, can prevent coming off of hair, and can hair follicle stimulating, activation scalp cells, promotes newborn, the treatment for alopecia have evident in efficacy, instant effect, safe and reliable, more after without recurrence, take the features such as simple.
Detailed description of the invention
Further illustrate the present invention by the following examples, but the invention is not restricted to these embodiments.
Embodiment 1
The medicine of hair growth, is obtained by the raw material of following weight parts: Fructus Ligustri Lucidi 20 parts, 25 parts, Poria, Radix Angelicae Sinensis 30 parts, Semen Sesami Nigrum 20 parts, Radix Tinosporae 25 parts, Herba Leonuri 20 parts, Radix Codonopsis 10 parts, Radix Ophiopogonis 15 parts, Semen Euryales 20 parts, Fel Sus domestica 10 parts, Herba Taxilli 15 parts, 10 parts, wheel prunus mume (sieb.) sieb.et zucc., Radix Bupleuri 1 part, Fructus chebulae immaturus 5 parts, Fructus Gardeniae 10 parts, Fructus Arctii 1 part, Radix Polygoni Multiflori 5 parts, Fructus Lycii 1 part, the Radix Angelicae Dahuricae 0.1 part, Semen Oroxyli 0.5 part, Fructus Sapindi Mukouossi 1 part, Rhizoma Curcumae 0.1 part.
The preparation method of medicine is: be alcohol-pickled 1.5 hours of 30% by raw material volumetric concentration, take out use water to rinse, the hot pot being placed in 180 ~ 220 DEG C stir-fries 30 minutes, takes out and rinses with water, then be dipped in the water of raw material weight 3 times, after being heated to boiling, decoct 2 hours under slight boiling condition, filter, filtrate is concentrated into 40% of its volume, add the modified starch of concentrated solution weight 1%, after spraying dry, gained powder is this medicine.
Embodiment 2
The medicine of hair growth, is obtained by the raw material of following weight parts: Fructus Ligustri Lucidi 25 parts, 30 parts, Poria, Radix Angelicae Sinensis 20 parts, Semen Sesami Nigrum 25 parts, Radix Tinosporae 30 parts, Herba Leonuri 10 parts, Radix Codonopsis 15 parts, Radix Ophiopogonis 20 parts, Semen Euryales 10 parts, Fel Sus domestica 15 parts, Herba Taxilli 20 parts, 1 part, wheel prunus mume (sieb.) sieb.et zucc., Radix Bupleuri 5 parts, Fructus chebulae immaturus 10 parts, Fructus Gardeniae 1 part, Fructus Arctii 5 parts, Radix Polygoni Multiflori 10 parts, Fructus Lycii 0.1 part, the Radix Angelicae Dahuricae 0.5 part, Semen Oroxyli 1 part, Fructus Sapindi Mukouossi 0.1 part, Rhizoma Curcumae 0.5 part.
The preparation method of medicine is: be alcohol-pickled 2 hours of 50% by raw material volumetric concentration, take out use water to rinse, the hot pot being placed in 180 ~ 220 DEG C stir-fries 20 minutes, takes out and rinses with water, then be dipped in the water of raw material weight 6 times, after being heated to boiling, decoct 3 hours under slight boiling condition, filter, filtrate is concentrated into 30% of its volume, add the modified starch of concentrated solution weight 2%, after spraying dry, gained powder is this medicine.
Embodiment 3
The medicine of hair growth, is obtained by the raw material of following weight parts: Fructus Ligustri Lucidi 30 parts, 20 parts, Poria, Radix Angelicae Sinensis 25 parts, Semen Sesami Nigrum 30 parts, Radix Tinosporae 20 parts, Herba Leonuri 15 parts, Radix Codonopsis 20 parts, Radix Ophiopogonis 10 parts, Semen Euryales 15 parts, Fel Sus domestica 20 parts, Herba Taxilli 10 parts, 5 parts, wheel prunus mume (sieb.) sieb.et zucc., Radix Bupleuri 10 parts, Fructus chebulae immaturus 1 part, Fructus Gardeniae 5 parts, Fructus Arctii 10 parts, Radix Polygoni Multiflori 1 part, Fructus Lycii 0.5 part, the Radix Angelicae Dahuricae 1 part, Semen Oroxyli 0.1 part, Fructus Sapindi Mukouossi 0.5 part, Rhizoma Curcumae 1 part.
The preparation method of medicine is: be alcohol-pickled 0.5 hour of 60% by raw material volumetric concentration, take out use water to rinse, the hot pot being placed in 180 ~ 220 DEG C stir-fries 25 minutes, takes out and rinses with water, then be dipped in the water of raw material weight 10 times, after being heated to boiling, decoct 1 hour under slight boiling condition, filter, filtrate is concentrated into 35% of its volume, add the modified starch of concentrated solution weight 3%, after spraying dry, gained powder is this medicine.
Toxicity test
Medicine during test drug in the embodiment of the present invention 1.Experimental animal is ICR kind white mice, body weight 20 ~ 22 grams, male and female half and half, totally 40.Test method is, fasting, after 15 hours, gives mice lavage 3 months by every day 20 grams/kilogram, long term toxicity test result shows, white mice body weight, liver function, renal function, hemogram etc. and matched group no significant difference, show that the safety of this medicine is large, belong to nontoxic rank.
Therapeutic effect
Use the obtained medicine of embodiment 1 to carry out proof test to the patient that 120 are suffered from alopecia, average cure rate reaches 77.5%.Wherein: 25 people's recoveries from illness in 30 people of less than 30 years old, wherein 1 people is invalid because taking other drug drug withdrawal; 23 people's recoveries from illness in 30 people of 30 ~ 40 years old, wherein 2 people are invalid because taking other drug drug withdrawal; 22 people's recoveries from illness in 30 people of 40 ~ 50 years old, wherein 1 people is invalid because taking other drug drug withdrawal; 23 people's recoveries from illness in 30 people of more than 50 years old, wherein 2 people drug withdrawal because taking other drug.

Claims (5)

1. the medicine of hair growth, it is characterized in that, obtained by the raw material of following weight parts: Fructus Ligustri Lucidi 20 ~ 30 parts, 20 ~ 30 parts, Poria, Radix Angelicae Sinensis 20 ~ 30 parts, Semen Sesami Nigrum 20 ~ 30 parts, Radix Tinosporae 20 ~ 30 parts, Herba Leonuri 10 ~ 20 parts, Radix Codonopsis 10 ~ 20 parts, Radix Ophiopogonis 10 ~ 20 parts, Semen Euryales 10 ~ 20 parts, Fel Sus domestica 10 ~ 20 parts, Herba Taxilli 10 ~ 20 parts, 1 ~ 10 part, wheel prunus mume (sieb.) sieb.et zucc., Radix Bupleuri 1 ~ 10 part, Fructus chebulae immaturus 1 ~ 10 part, Fructus Gardeniae 1 ~ 10 part, Fructus Arctii 1 ~ 10 part, Radix Polygoni Multiflori 1 ~ 10 part, Fructus Lycii 0.1 ~ 1 part, the Radix Angelicae Dahuricae 0.1 ~ 1 part, Semen Oroxyli 0.1 ~ 1 part, Fructus Sapindi Mukouossi 0.1 ~ 1 part, Rhizoma Curcumae 0.1 ~ 1 part.
2. medicine according to claim 1, it is characterized in that, the weight portion of described raw material is: Fructus Ligustri Lucidi 20 parts, 25 parts, Poria, Radix Angelicae Sinensis 30 parts, Semen Sesami Nigrum 20 parts, Radix Tinosporae 25 parts, Herba Leonuri 20 parts, Radix Codonopsis 10 parts, Radix Ophiopogonis 15 parts, Semen Euryales 20 parts, Fel Sus domestica 10 parts, Herba Taxilli 15 parts, 10 parts, wheel prunus mume (sieb.) sieb.et zucc., Radix Bupleuri 1 part, Fructus chebulae immaturus 5 parts, Fructus Gardeniae 10 parts, Fructus Arctii 1 part, Radix Polygoni Multiflori 5 parts, Fructus Lycii 1 part, the Radix Angelicae Dahuricae 0.1 part, Semen Oroxyli 0.5 part, Fructus Sapindi Mukouossi 1 part, Rhizoma Curcumae 0.1 part.
3. medicine according to claim 1, it is characterized in that, the weight portion of described raw material is: Fructus Ligustri Lucidi 25 parts, 30 parts, Poria, Radix Angelicae Sinensis 20 parts, Semen Sesami Nigrum 25 parts, Radix Tinosporae 30 parts, Herba Leonuri 10 parts, Radix Codonopsis 15 parts, Radix Ophiopogonis 20 parts, Semen Euryales 10 parts, Fel Sus domestica 15 parts, Herba Taxilli 20 parts, 1 part, wheel prunus mume (sieb.) sieb.et zucc., Radix Bupleuri 5 parts, Fructus chebulae immaturus 10 parts, Fructus Gardeniae 1 part, Fructus Arctii 5 parts, Radix Polygoni Multiflori 10 parts, Fructus Lycii 0.1 part, the Radix Angelicae Dahuricae 0.5 part, Semen Oroxyli 1 part, Fructus Sapindi Mukouossi 0.1 part, Rhizoma Curcumae 0.5 part.
4. medicine according to claim 1, it is characterized in that, the weight portion of described raw material is: Fructus Ligustri Lucidi 30 parts, 20 parts, Poria, Radix Angelicae Sinensis 25 parts, Semen Sesami Nigrum 30 parts, Radix Tinosporae 20 parts, Herba Leonuri 15 parts, Radix Codonopsis 20 parts, Radix Ophiopogonis 10 parts, Semen Euryales 15 parts, Fel Sus domestica 20 parts, Herba Taxilli 10 parts, 5 parts, wheel prunus mume (sieb.) sieb.et zucc., Radix Bupleuri 10 parts, Fructus chebulae immaturus 1 part, Fructus Gardeniae 5 parts, Fructus Arctii 10 parts, Radix Polygoni Multiflori 1 part, Fructus Lycii 0.5 part, the Radix Angelicae Dahuricae 1 part, Semen Oroxyli 0.1 part, Fructus Sapindi Mukouossi 0.5 part, Rhizoma Curcumae 1 part.
5. the medicine according to any one of Claims 1 to 4, it is characterized in that, the preparation method of medicine is be 30% ~ 60% alcohol-pickled 0.5 ~ 2 hour by raw material volumetric concentration, taking-up water rinses, the hot pot being placed in 180 ~ 220 DEG C stir-fries 20 ~ 30 minutes, take out and rinse with water again, then be dipped in the water of raw material weight 3 ~ 10 times, after being heated to boiling, decoct 1 ~ 3 hour under slight boiling condition, filter, filtrate is concentrated into 30% ~ 40% of its volume, add the modified starch of concentrated solution weight 1% ~ 3%, after spraying dry, gained powder is this medicine.
CN201510837396.XA 2015-11-27 2015-11-27 Medicine for treating alopecia Pending CN105343775A (en)

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103768375A (en) * 2012-10-28 2014-05-07 烟台大洋制药有限公司 Medicine for treating alopecia

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103768375A (en) * 2012-10-28 2014-05-07 烟台大洋制药有限公司 Medicine for treating alopecia

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
朱彩霞等: "疏肝法的临床运用", 《内蒙古中医药》 *

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