CN105343407A - Traditional Chinese medicine composition for treating ear eczema - Google Patents

Abstract

The invention belongs to the technical field of medicines and particularly relates to traditional Chinese medicine composition for treating ear eczema. The composition comprises traditional Chinese medicines in parts by weight as follows: 4-6 parts of seeds of Livistonachinensis (Jacq.) R.Br., 4-6 parts of Lysionotus pauciflorus Maxim., 4-6 parts of roots of candolle pimpinella, 4-6 parts of Pendasacme championii Benth., 4-6 parts of Arisaema sikokianum Fuanch., 4-6 parts of Abacopteris multilineata (Wall.) Ching, 4-6 parts of all-grass of winkled marshweed, 4-6 parts of Teucrium pernyi Franch., 4-6 parts of Lespedeza pilosa (Thunb.) Sieb. et Zucc. and 4-6 parts of Coreopsis lanceolata L.. All the traditional Chinese medicines are used together to play effects of clearing away heat, removing toxins, promoting blood circulation to remove meridian obstruction, removing blood stasis, eliminating stagnation and relieving swelling and pain. The composition is used for treating the ear eczema and has the advantages of high cure rate and high total effective rate.

Description

A kind of Chinese medicine composition for the treatment of ear eczema

Technical field

The invention belongs to medical art, be specifically related to a kind of Chinese medicine composition for the treatment of ear eczema.

Background technology

Ear eczema. the traditional Chinese medical science, also known as " eczema of ear ", mostly occurs at postauricular fold place.Also show helix top and external auditory meatus, skin lesion shows as erythema, stream is grown, formed a scab and chap.Sometimes being with seborrheica, normal lateral symmetry, is a kind of eczema of clinical common privileged sites.Have the advantages that prevalence is high, the course of disease is long.Its cause of disease is complicated.It is generally acknowledged that genetic anaphylactic predisposition is the Etiological of morbidity.In addition the application etc. of endocrine, Nervous and Mental Factors, lectin from hemolymph, medicine, food, cosmetics is all relevant to the morbidity of eczema.Modern medicine thinks that eczema is a kind of allergic inflammation dermatoses, very close with immune system relation.Oral antihistaminic and topical steroid hormone therapy. easily recurrent exerbation. and prolonged application has certain side effect.

Summary of the invention

Technical problem to be solved by this invention avoids the weak point existing for above-mentioned prior art, provides a kind of Chinese medicine composition for the treatment of ear eczema.

The present invention is achieved through the following technical solutions:

Treat a Chinese medicine composition for ear eczema, be made up of the Chinese medicine of following weight portion:

Chinese fanpalm seed 4-6 part, Herba Lysionoti Pauciflori 4-6 part, Radix Pimpinellae Candolleanae 4-6 part, Radix Pentasacmi championii 4-6 part, Rhizoma Arisaemati 4-6 part, Abacopteris multilineata(Wall.) Ching (Pronephrium multilineatum (Wall.) ching 4-6 part, Herba Limnophilae rugosae 4-6 part, Radix Teucrii Pernyi 4-6 part, Herba lespedezae pilosae 4-6 part, Folium Coreopsis lanceolatae 4-6 part.

Preferably, the Chinese medicine composition of above-mentioned treatment ear eczema, is made up of the Chinese medicine of following weight portion:

Chinese fanpalm seed 5-7 part, Herba Lysionoti Pauciflori 5-7 part, Radix Pimpinellae Candolleanae 5-7 part, Radix Pentasacmi championii 5-7 part, Rhizoma Arisaemati 5-7 part, Abacopteris multilineata(Wall.) Ching (Pronephrium multilineatum (Wall.) ching 5-7 part, Herba Limnophilae rugosae 5-7 part, Radix Teucrii Pernyi 5-7 part, Herba lespedezae pilosae 5-7 part, Folium Coreopsis lanceolatae 5-7 part.

Preferred, the Chinese medicine composition of above-mentioned treatment ear eczema, is made up of the Chinese medicine of following weight portion:

Chinese fanpalm seed 6 parts, Herba Lysionoti Pauciflori 6 parts, Radix Pimpinellae Candolleanae 6 parts, Radix Pentasacmi championii 6 parts, Rhizoma Arisaemati 6 parts, Abacopteris multilineata(Wall.) Ching (Pronephrium multilineatum (Wall.) ching 6 parts, Herba Limnophilae rugosae 6 parts, Radix Teucrii Pernyi 6 parts, Herba lespedezae pilosae 6 parts, Folium Coreopsis lanceolatae 6 parts.

The ratio of above weight proportion is through that science screening obtains, and for especial patient, as serious symptom or mild, fat or modest patient, can the proportioning of amount of corresponding adjustment composition, and increase or reduce being no more than 100%, drug effect is substantially constant.

The weight portion of said medicine, if in units of g, the normally consumption of 1 dose.

The indication of medicine of the present invention: be used for the treatment of ear eczema.

The method of preparation and use of medicine of the present invention: be ground into fine powder by after each composition Chinese medicine mixing of medicine of the present invention, for subsequent use.Get fine powder when using appropriate, mix well deposited affected part with water, Chinese liquor, tea, vinegar, Ovum Gallus domesticus album, vaseline, Oleum sesami, Oleum Camelliae or glycerol etc.

The standard of fine powder is on the books in Chinese Pharmacopoeia 2010 editions 1 annex.

The taboo item of medicine of the present invention: the fasting for the treatment of period in a medicine is greasy, raw and cold, the smelling of fish or mutton, irritant and stodgy food.

In medicine of the present invention,

Chinese fanpalm seed another name seed of Livistona chinensis R.Br. is babassu Semen livistonae chinensis Livistonachinensis(Jacq.) seed of R.Br..Sweet in the mouth; Bitter; Property is put down.Function blood circulation promoting and blood stasis dispelling; Hard masses softening and resolving.Main chronic hepatitis; Lump in the abdomen.

The black black bone of Herba Lysionoti Pauciflori another name, Radix Loxostigmatis griffithii, Lysionotus pauciflorus Maxim., little Herba Lycopi, Herba Lysionoti carnosae, rock tea, Herba Ophiorrhizae japonicae, rock orchid, Ba Yancao, the red grass of lung, Semen Benincasae grass, Parmelia saxatilis Ach., puerperal tea, Eupatorium formosanum Hayata., stone Radix Notoginseng, Shi Hu, Cicerbita azurea (Ledeb.) Beavuerd, Radix Loxostigmatis griffithii, stone Fructus Myricae rubrae, rock head Radix Notoginseng, rock strip, bamboo do not sting, member orchid, pattern rake.For the herb of Gesneriaceae Herba Lysionoti Pauciflori LysionotuspauciflorusMaxim..Bitter in the mouth; Pungent; Property is put down.Function wind dehumidifies; Preventing phlegm from forming and stopping coughing; Blood stasis dispelling stimulates the menstrual flow.Main air pain of dampness syndrome; Cough with asthma abundant expectoration; Menoxenia; Dysmenorrhea; Traumatic injury.

That Radix Pimpinellae Candolleanae another name Rhizoma valerianae latifoliae, mountain Radix Angelicae Sinensis, Horse hoof Radix Saposhnikoviae, JIUYUE Pemisetum flaccidum Griseb, all over the body string, tripodia Cicadae, Pemisetum flaccidum Griseb, Yangshan are smelly, Rhizoma typhonii divaricati, clearly Radix Angelicae Sinensis, sheep are had a strong smell is smelly, Herba Calthae, Fructus Piperis, lamb have a strong smell, Radix Pimpinellae Candolleanae, nine Ns dry, sheep mountain is smelly, Great Cold medicine, grass of cooling down, rabbit ear Radix Saposhnikoviae, little hero, little Flos Chrysanthemi, be root or the herb of samphire Folium Pruni Pimpinella anisum Linn. PimpinellacandolleanaWighy day Arn.Acrid in the mouth; Micro-hardship; Warm in nature.Return lung; Spleen; Stomach; Liver Channel.Function warming spleen and stomach for dispelling cold; Promoting the circulation of QI to relieve pain; Expelling wind and activating blood circulation; Removing toxic substances and promoting subsidence of swelling.The cold pain of main gastral cavity abdomen; Dyspepsia; Dysentery; Flu; Cough; Infantile convulsion; Leucorrhea; Hernia; The testis swelling and hanging down of either of the testes; Scrofula; Treating swelling and pain by traumatic injury; Carbuncle sore tumefacting virus; Venom.

Radix Pentasacmi championii another name five, southern stone Herba seu Radix Metaplexis hemsleyanae, false fourth Diao Zhu, Herba Pteridis Multifidae, full grass, Radix Homonoiae Ripariae, be the herb of dicotyledon medicine asclepiadaceae stone Herba seu Radix Metaplexis hemsleyanae PendasacmechampioniiBenth..Bitter in the mouth; Micro-pungent; Cool in nature.Return liver; Gallbladder meridian.Function is fallen apart wind heat clearing away; Removing toxic substances and promoting subsidence of swelling.Main anemopyretic cold; Cough; Pharyngalgia; Conjunctival congestion; Hepatitis; Venom.

Rhizoma Arisaemati another name LUBIANHUANG, Serpentis Semen Maydis, old Serpentis Semen Maydis are the tuber of aroid Rhizoma Arisaemati ArisaemasikokianumFuanch. day or full edge Rhizoma Arisaemati Sav.var.s day tatum (Makino) Hand.-Mazz [A.sazensoovar.serratumMakino] 2.ArisaemasikokianumFranch. day Sav..Bitter in the mouth, pungent; Warm in nature.Return lung; Liver Channel.Function drying dampness to eliminate phlegm; Relieving spasm by subduing liver-wind; Reducing swelling and alleviating pain.Main productive cough due to phlegm-damp; Dizziness due to wind-phlegm; Epilepsy; Apoplexy; Facial hemiparalysis; Tetanus; Carbuncle; Venom.

Abacopteris multilineata(Wall.) Ching (Pronephrium multilineatum (Wall.) ching calls large plumage crescent Herba pteridii latiusculi, Coniogramme japonica (Thunb.) Diels, derives from fern Athyriaceae Abacopteris multilineata(Wall.) Ching (Pronephrium multilineatum (Wall.) ching Abacopterismultilineata(Wall.) Ching, is used as medicine with root stock.Bitter in the mouth, cold in nature.Function dredge the meridian passage, dampness removing of regulating the flow of vital energy.Cure mainly impairment caused by overstrain, peratodynia, dysentery, menoxenia.

Herba Limnophilae rugosae another name Tian Gencao, water mint, Rhizoma begoniae pedatifidae, water Herba Schizonepetae, ripples perfume, wrinkle leaf Herba Limnophilae sessiliflorae are the herb of goatweed Limnophila rugosa NitellaexpansaAllen, Limnophilarugosa (Roth) Merr..Acrid in the mouth; Sweet; Warm in nature.Return lung; Spleen; Stomach warp.Function invigorating spleen to remove dampness; Activating QI to eliminate phlegm.Main edema; Stomachache; Distension and fullness of the chest and abdomen; Cough; Children's's infantile dyspepsia; Furuncle.

Radix Teucrii Pernyi another name Mount Lushan spice, derives from Labiatae and spends Phryganeajaponica Ml. TeucriumpernyiFranch. in vain, be used as medicine with root.Taste is micro-sweet, warm in nature.Function invigorating spleen to remove dampness, removing toxic substances.Cure mainly dysentery.

Herba lespedezae pilosae another name Herba cassiae torae, derives from pulse family Lespedeza plant Herba lespedezae pilosae Lespedezapilosa(Thunb.) Sieb. day Zucc., is used as medicine with root and Herb.Bitter in the mouth, pungent, property is put down.Function heat clearing away eliminating stagnation, promoting blood circulation and stopping pain, line water detumescence.For lymphoid tuberculosis, cold abscess, deficiency-heat is not moved back, edema, waist hamstring osteodynia; Mastitis are controlled in external.

Folium Coreopsis lanceolatae another name Coreopsis lanceolata, sword-like leave coreopsis, derive from Compositae Folium Coreopsis lanceolatae CoreopsislanceolataL., with all herbal medicine.Acrid in the mouth, property is put down.Function blood stasis dispersing and deswelling, heat-clearing and toxic substances removing.Cure mainly knife injury, innominate toxic swelling.

In medicine of the present invention, Chinese fanpalm seed blood circulation promoting and blood stasis dispelling, hard masses softening and resolving; Herba Lysionoti Pauciflori heat clearing and damp drying, reducing swelling and alleviating pain; Radix Pimpinellae Candolleanae promoting the circulation of QI to relieve pain, dissipating blood stasis for subsidence of swelling; Radix Pentasacmi championii falls apart wind heat clearing away, removing toxic substances and promoting subsidence of swelling; Rhizoma Arisaemati drying dampness to eliminate phlegm, reducing swelling and alleviating pain; Abacopteris multilineata(Wall.) Ching (Pronephrium multilineatum (Wall.) ching dredge the meridian passage, regulating QI to expel dampness; Herba Limnophilae rugosae, Radix Teucrii Pernyi invigorating spleen to remove dampness, activating QI to eliminate phlegm; Herba lespedezae pilosae heat clearing away eliminating stagnation, promoting blood circulation and stopping pain; Folium Coreopsis lanceolatae blood stasis dispersing and deswelling, heat-clearing and toxic substances removing.All medicines share, and play heat-clearing and toxic substances removing altogether, promoting blood circulation to remove obstruction in the collateral, blood stasis-eliminating and stagnation-dissipating, the effect of reducing swelling and alleviating pain.

Detailed description of the invention

Below in conjunction with specific embodiment, the present invention is further described, so that those skilled in the art more understands the present invention, but does not therefore limit the present invention.

Embodiment 1

Treat a Chinese medicine composition for ear eczema, each crude drug weight proportion is as follows:

Chinese fanpalm seed 60g, Herba Lysionoti Pauciflori 60g, Radix Pimpinellae Candolleanae 60g, Radix Pentasacmi championii 60g, Rhizoma Arisaemati 60g, Abacopteris multilineata(Wall.) Ching (Pronephrium multilineatum (Wall.) ching 60g, Herba Limnophilae rugosae 60g, Radix Teucrii Pernyi 60g, Herba lespedezae pilosae 60g, Folium Coreopsis lanceolatae 60g.

Method of preparation and use: be ground into fine powder by after each composition Chinese medicine mixing of medicine of the present invention, for subsequent use.Get fine powder when using appropriate, mix well deposited affected part with water, Chinese liquor, tea, vinegar, Ovum Gallus domesticus album, vaseline, Oleum sesami, Oleum Camelliae or glycerol etc.

Embodiment 2

Treat a Chinese medicine composition for ear eczema, each crude drug weight proportion is as follows:

Chinese fanpalm seed 50g, Herba Lysionoti Pauciflori 70g, Radix Pimpinellae Candolleanae 50g, Radix Pentasacmi championii 70g, Rhizoma Arisaemati 50g, Abacopteris multilineata(Wall.) Ching (Pronephrium multilineatum (Wall.) ching 70g, Herba Limnophilae rugosae 50g, Radix Teucrii Pernyi 70g, Herba lespedezae pilosae 50g, Folium Coreopsis lanceolatae 70g.

Method of preparation and use is with embodiment 1.

Embodiment 3

Treat a Chinese medicine composition for ear eczema, each crude drug weight proportion is as follows:

Chinese fanpalm seed 70g, Herba Lysionoti Pauciflori 50g, Radix Pimpinellae Candolleanae 70g, Radix Pentasacmi championii 50g, Rhizoma Arisaemati 70g, Abacopteris multilineata(Wall.) Ching (Pronephrium multilineatum (Wall.) ching 50g, Herba Limnophilae rugosae 70g, Radix Teucrii Pernyi 50g, Herba lespedezae pilosae 70g, Folium Coreopsis lanceolatae 50g.

Method of preparation and use is with embodiment 1.

Embodiment 4

Treat a Chinese medicine composition for ear eczema, each crude drug weight proportion is as follows:

Chinese fanpalm seed 40g, Herba Lysionoti Pauciflori 60g, Radix Pimpinellae Candolleanae 40g, Radix Pentasacmi championii 60g, Rhizoma Arisaemati 40g, Abacopteris multilineata(Wall.) Ching (Pronephrium multilineatum (Wall.) ching 60g, Herba Limnophilae rugosae 40g, Radix Teucrii Pernyi 60g, Herba lespedezae pilosae 40g, Folium Coreopsis lanceolatae 60g.

Method of preparation and use is with embodiment 1.

Embodiment 5

Treat a Chinese medicine composition for ear eczema, each crude drug weight proportion is as follows:

Chinese fanpalm seed 60g, Herba Lysionoti Pauciflori 40g, Radix Pimpinellae Candolleanae 60g, Radix Pentasacmi championii 40g, Rhizoma Arisaemati 60g, Abacopteris multilineata(Wall.) Ching (Pronephrium multilineatum (Wall.) ching 40g, Herba Limnophilae rugosae 60g, Radix Teucrii Pernyi 40g, Herba lespedezae pilosae 60g, Folium Coreopsis lanceolatae 40g.

Method of preparation and use is with embodiment 1.

Carried out clinical pharrnacokinetics test to medicine of the present invention, Details as Follows:

1 data and method

1.1 physical data choose 200 routine ear eczema patients. all meet the clinical criteria of ear eczema.Get rid of and have severe cardiac, liver, kidney or endocrinopathy person; Gestation and women breast-feeding their children: infant and have allergy sufferers to observed ingredient; Antihistamine drug or corticosteroids medicine person was applied in 1w before medication.All patients are divided into treatment group and each 100 examples of matched group at random.In treatment group man 45 example, female 55 example: the age 28 ~ 65 (average 45) year; Course of disease 3w ~ 3 year, average 1.5 years.In matched group man 42 example, female 58 example: the age 27 ~ 66 (average 46) year; Course of disease 3w ~ 3 year.Average 1.6 years.Two groups of physical data compare without significant difference (P>0.05), have comparability.

1.2 method matched group patients only give mupirocin Ointment in Treatment. morning every day, each use in evening 1 time.14d is 1 course for the treatment of.The fine drug powder that treatment group gets the embodiment of the present invention 1 uses the pasty state that strong tea water furnishing is thicker in right amount, is coated on the skin around ear eczema position, treats that its natural drying comes off, and every day early, evening respectively uses 1 time, and treatments period is stopped using other drug.14d is 1 course for the treatment of.The clean and dry of protection affected part is all noted after two groups of patient's liniments. treatments period stops other corticosteroid hormones of external and antihistaminic for oral administration.Observe two groups of patient treatment 1w and treatment 2w clinical efficacy.

1.3 curative effect determinate standard recoveries from illness: skin lesion disappears completely, no conscious sympton: effective: skin lesion disappears more than 60%. subjective symptoms is obviously improved; Effective: skin lesion disappears more than 30%, and subjective symptoms alleviates: invalid: skin lesion disappears less than 30%, and subjective symptoms is not improved.

1.4 statistical procedures data acquisition SPSS13.0 statistics softwares process.Enumeration data adopts example (percentage rate) to represent, row x checks.P<0.05 differential is different statistical significance

2 results

2.1 liang of group treatment 1w Clinical efficacy comparison treatment group total effective rate 89.00%. matched group total effective rate 77.00%., two groups of comparing differences have statistical significance (P<0.05).In table 1.

Table 1 liang group treatment 1w Clinical efficacy comparison (n)

Group	n	Recovery from illness	Effective	Effectively	Invalid	Total effective rate (%)
							Treatment group	100	52*	23	14	11	89.00*
Matched group	100	31	29	17	23	77.00

Note: compared with matched group, * P<0.05.

2.2 liang of group treatment 2w Clinical efficacy comparison treatment group total effective rates 96.00%, matched group total effective rate 88.00%, two groups of comparing differences have statistical significance (P<0.05).In table 2.

Table 2 liang group treatment 2w Clinical efficacy comparison (n)

Group	n	Recovery from illness	Effective	Effectively	Invalid	Total effective rate (%)
							Treatment group	100	58*	28	10	4	96.00*
Matched group	100	35	32	21	12	88.00

Note: compared with matched group, * P<0.05.

Claims (3)

1. treat a Chinese medicine composition for ear eczema, be made up of the Chinese medicine of following weight portion:

Chinese fanpalm seed 4-6 part, Herba Lysionoti Pauciflori 4-6 part, Radix Pimpinellae Candolleanae 4-6 part, Radix Pentasacmi championii 4-6 part, Rhizoma Arisaemati 4-6 part, Abacopteris multilineata(Wall.) Ching (Pronephrium multilineatum (Wall.) ching 4-6 part, Herba Limnophilae rugosae 4-6 part, Radix Teucrii Pernyi 4-6 part, Herba lespedezae pilosae 4-6 part, Folium Coreopsis lanceolatae 4-6 part.

2. the Chinese medicine composition for the treatment of ear eczema according to claim 2, is characterized in that, is made up of the Chinese medicine of following weight portion:

Chinese fanpalm seed 5-7 part, Herba Lysionoti Pauciflori 5-7 part, Radix Pimpinellae Candolleanae 5-7 part, Radix Pentasacmi championii 5-7 part, Rhizoma Arisaemati 5-7 part, Abacopteris multilineata(Wall.) Ching (Pronephrium multilineatum (Wall.) ching 5-7 part, Herba Limnophilae rugosae 5-7 part, Radix Teucrii Pernyi 5-7 part, Herba lespedezae pilosae 5-7 part, Folium Coreopsis lanceolatae 5-7 part.

3. the Chinese medicine composition for the treatment of ear eczema according to claim 2, is characterized in that, is made up of the Chinese medicine of following weight portion:

Chinese fanpalm seed 6 parts, Herba Lysionoti Pauciflori 6 parts, Radix Pimpinellae Candolleanae 6 parts, Radix Pentasacmi championii 6 parts, Rhizoma Arisaemati 6 parts, Abacopteris multilineata(Wall.) Ching (Pronephrium multilineatum (Wall.) ching 6 parts, Herba Limnophilae rugosae 6 parts, Radix Teucrii Pernyi 6 parts, Herba lespedezae pilosae 6 parts, Folium Coreopsis lanceolatae 6 parts.