CN105340926A - Bactericidal composition containing mandipropamid and polyoxins and application of bactericidal composition - Google Patents
Bactericidal composition containing mandipropamid and polyoxins and application of bactericidal composition Download PDFInfo
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- CN105340926A CN105340926A CN201510916731.5A CN201510916731A CN105340926A CN 105340926 A CN105340926 A CN 105340926A CN 201510916731 A CN201510916731 A CN 201510916731A CN 105340926 A CN105340926 A CN 105340926A
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Abstract
The invention provides a bactericidal composition containing mandipropamid and polyoxins and application of the bactericidal composition preventing and curing cucumber downy mildew, belonging to the technical field of combination of pesticides. The active ingredients of the bactericidal composition are mandipropamid and polyoxins, and the balance is auxiliary ingredients including a wetting agent, a dispersing agent, a disintegrating agent, a defoaming agent, a thickening agent, an antifreezing agent, an anti-caking agent, filler, a binding agent, a solvent, an inert carrier and the like; the mass ratio of the active ingredients of mandipropamid to polyoxins is (1:20) to (20:1); the two of mandipropamid and polyoxins account for 1 percent to 80 percent of the total mass of the bactericidal composition. The bactericidal composition can be further prepared into formulations of suspending agents, wettable powder and water dispersible granules. The bactericidal composition provided by the invention is reasonable in component, good in bactericidal effect, outstanding in synergistic effect, and good in safety to crops and meets the safety requirements of pesticide preparations; the generation of resistance can be slowed, and the bactericidal composition has better control effect to cucumber downy mildew.
Description
Technical field
The invention belongs to technical field of pesticide combination, be specifically related to a kind of synergetic pesticide composition, particularly relate to a kind of bactericidal composition containing mandipropamid and polyoxin and the application in control cucumber downy mildew thereof.
Background technology
Mandipropamid (mandipropamid, Revus), is mainly used in that the crops such as grape, potato, lichee, tomato prevent and treat the pathogen such as Phytophthora and Peronospora and causes disease.Medicament, by suppressing the synthesis of germ phosphatide, suppresses sporulation and spore germination and mycelial growth, can kill the spore between latent period, reach protection and treat dual preventive effect.After this medicament sprays can at short notice absorb by the wax on plant top layer, protection blade do not receive germ infringement.
Polyoxin (Polyoxin), chemical name is peptide pyrimidine nucleoside, it is the metabolite that cocoa streptomycete A Su mutation (Stroptomycescacaoivar.asoensis) produces, it is absorption farm antibiotics in wide spectrum, the mechanism of action mainly disturbs the chitinous biosynthesis of pathogenic cell wall, gemma contacts medicament and expands and break with mycelium, finally dead; This medicament has and suppresses that germ spore produces, scab expands and the effect of Promoting plant growth simultaneously.Polyoxin is a kind of anti-microbial type biopesticide of imitating high, noresidue, broad spectrum activity, be mainly used in preventing and treating on the economic crops such as melon and fruit, vegetables common by diseases such as fungus-caused downy mildew, black spot, powdery mildews, there is obvious control efficiency to the banded sclerotial blight of paddy rice, damping off simultaneously, in reasonable employment situation, energy Promoting plant growth, plays the effect of somatotropin.
In agricultural production, chemical control is mainly taked effectively to suppress cucumber downy mildew, because cucumber downy mildew belongs to the pathogen of resistance risk, long-term unreasonable use chemical agent, cause the pesticide resistance of cucumber downy mildew to increase the weight of thereupon, correspondingly cause residue of pesticide excessive problem.The medicament different to mechanism of action carries out composite, can not only expand fungicidal spectrum and reduce pathogen resistance risk, extending the Pesticide use life-span, can also improve the object that preventive effect reaches increasing both production and income and extends the drug effect phase simultaneously.
Summary of the invention
On the basis of lab screening and field trial, we filter out a kind of bactericidal composition containing mandipropamid and polyoxin, have obvious sterilization synergistic effect to cucumber downy mildew.
Another object of the present invention is to provide the application of bactericidal composition in control cucumber downy mildew of mandipropamid and polyoxin.
A kind of bactericidal composition containing mandipropamid and polyoxin of the present invention, its active ingredient is mandipropamid and polyoxin, all the other are auxiliary element, comprise wetting agent, dispersant, disintegrant, defoamer, thickener, antifreezing agent, anticaking agent, filler, binding agent, solvent, inert carrier etc.; The mass ratio of active ingredient mandipropamid and polyoxin is 1:20 ~ 20:1, more preferably 1:5 ~ 5:1; And the percentage that both mandipropamid and polyoxin account for bactericidal composition gross mass is 1% ~ 80%, be preferably 5% ~ 60%.
The formulation that bactericidal composition of the present invention can be prepared further comprises suspending agent, wetting powder, water-dispersible granules.
Described bactericidal composition is suspending agent, and by mass percent be 100% calculating, the mass percentage of its component is:
Mandipropamid 2.5 ~ 30%
Polyoxin 2.5 ~ 30%
Wetting agent 2 ~ 4%
Dispersant 4 ~ 6%
Defoamer 0.02 ~ 0.1%
Thickener 0.1 ~ 3%
Antifreezing agent 2 ~ 8%
Deionized water complements to 100%
And the mass ratio of mandipropamid and polyoxin is 1:5 ~ 5:1;
Wherein said wetting agent is one or more the combination in lignosulfite solid content, aliphatic alcohol polyethenoxy base ether, Negel, lignosulfonates, aliphatic alcohol polyethenoxy base ether, alkylaryl polyoxyethylene ether, lauryl alcohol polyethylene glycol oxide base ether sodium sulfate, alkyl naphthalene formaldehyde condensate sulfonates, fatty alcohol ethylene oxide adduct phosphate.
Wherein said dispersant is one or more the combination in alkyl naphthalene formaldehyde condensate sulfonates, fatty alcohol ethylene oxide adduct phosphate, lignosulfonates, polymerization alkylaryl sulfonates, alkylphenol-polyethenoxy base ether formaldehyde condensation products sulphate, Sodium Polyacrylate, alkylphenol-polyethenoxy base phosphate, lignin and derivative desulfonate polycarboxylate thereof, succinic acid, sulfonated ester.
Wherein said defoamer is organosilicon ketone, C
10-20saturated fatty acid and ester, C
14-20saturated monocarboxylic acid and ammonium salt, nonionic and compound thereof, C
8-10one or more combination in aliphatic carboxylic acid and ester class thereof or ester-ether type compound.
Wherein said thickener is one or more the combination in gum Arabic, xanthan gum, polyvinyl alcohol, PVP, disperse silicic acid, carboxymethyl cellulose, polyvinyl acetate, Magnesiumaluminumsilicate, Sodium Polyacrylate, gaseous silicon oxide.
Wherein said antifreezing agent is one or more the combination in ethylene glycol, glycerine, propane diols, glycerine, glycerine-ether diglycol or methyl propylene diglycol.
Preparation method's concrete steps of this suspending agent are: according to above-mentioned recipe requirements by former for mandipropamid medicine, the former medicine of polyoxin, wetting agent, dispersant, antifreezing agent, part thickener, part defoamer, portions of de-ionized water carries out 30min by high-speed mixer and just mixes, proceed to mixer mill in ball mill and be broken to particle diameter≤200 order, proceed to afterwards in skin grinder, add residue deionized water simultaneously, residue thickener, residue defoamer is to regulate mixture viscosity and to eliminate the foam produced in shear history, carry out the shearing of sand milling ultramicro grinding, forming final sand milling is emulsion (particle diameter≤3um, viscosity is 100 ~ 1000mPas), last material adds in homogenizer, again process 30 ~ 50min, the suspending agent of final obtained inventive mixture.
Described bactericidal composition is wetting powder, and by mass percent be 100% calculating, the mass percentage of its component is:
Mandipropamid 2.5 ~ 30%
Polyoxin 2.5 ~ 30%
Inert carrier 10 ~ 20%
Dispersant 3 ~ 5%
Wetting agent 0.5 ~ 3%
Anticaking agent 1 ~ 3%
Defoamer 0.05 ~ 1%
Filler complements to 100%
And the mass ratio of mandipropamid and polyoxin is 1:5 ~ 5:1;
Wherein said inert carrier is one or more the combination in diatomite, bentonite, attapulgite, potter's clay, kaolin, talcum powder.
Wherein said wetting agent is that tea is withered, Chinese honey locust, silkworm excrement, sodium alkyl sulfonate, alkylbenzenesulfonate, alkylnaphthalene sulfonate, aliphatic alcohol sulfate, alkylphenol-polyethenoxy base ether sodium sulfate, phosphate, alkylphosphonic, fatty alcohol ethylene oxide adduct phosphate, dialkyl succinylsuccinate sulfonate, this sulfonate of alkyl amide, sorbitan fatty acid ester-span series, alkyl phenyl polyethylene oxides ether succinate monoester sulfonate, sorbitan fatty acid ester polyoxyethylene ether-twccnm series, one or more combination in alkylphenol formaldehyde condensation product polyoxyethylene ether.
Wherein said dispersant is one or more the combination in phosphoric acid ester, phosphate, sulfonate, lignin sulfonate, naphthalenesulfonate, benzenesulfonates, sodium phosphate trimer, calgon, polyvinylpyrrolidone, Sodium Polyacrylate, polyethylene glycol.
Wherein said defoamer is silicone, C
8-C10one or more combination in fatty alcohol, oxirane and propylene oxide block copolymer.
Wherein said anticaking agent is one or more the combination of white carbon, sodium silicoaluminate, silica or tricalcium phosphate.
Wherein said filler is one or more the combination in talcum powder, clay, diatomite, vermiculite, potter's clay, kaolin, attapulgite, white carbon.
The preparation method of this wetting powder be by former for mandipropamid medicine and the former drug mill of polyoxin broken, again the former medicine after grinding and wetting agent, dispersant, inert carrier, part defoamer, filler, anticaking agent added stirred tank and carry out premixed in adding, afterwards material is proceeded to skin grinder, add residue defoamer simultaneously and mix again (particle diameter≤100um) after grinding, levigate in airslide disintegrating mill for mixture (particle diameter 1 ~ 20um) is mixed again, the wetting powder of finally this combination obtained.
Described bactericidal composition is water dispersible granules, and by mass percent be 100% calculating, the mass percentage of its component is:
Mandipropamid 2.5 ~ 30%
Polyoxin 2.5 ~ 30%
Inert carrier 10 ~ 20%
Solvent 10 ~ 15%
Dispersant 2 ~ 5%
Wetting agent 1 ~ 3%
Disintegrant 2 ~ 5%
Binding agent 0.1 ~ 3%
Defoamer 0.01 ~ 0.5%
Filler complements to 100%
And the mass ratio of mandipropamid and polyoxin is 1:5 ~ 5:1;
Wherein said inert carrier is one or more combination in diatomite, bentonite, attapulgite, potter's clay, kaolin.
Wherein said dispersant is one or more the mixture in anion surfactant and non-ionic surface active agent.Anion surfactant is phosphoric acid ester, metal carboxylate, lignin sulfonate, polystyrene-based phenol polyethenoxy ether Sulfates, benzenesulfonates or succinic acid salt; Non-ionic surface active agent is fatty alcohol copolymer, macromolecular grafted copolymer, triphenyl vinyl phenol polyoxyethylene poly-oxygen propylene aether, polystyrene-based phenol polyethenoxy ethers.
Wherein said wetting agent is one or more the combination in polystyrene-based polyethenoxy ether class, polyoxyethylene nonylphenol ether class, alkyl naphthalene sulfonic acid salt and fatty alcohol polyethenoxy ether class.
Wherein said disintegrant is ammonium sulfate, anhydrous sodium sulfate, CaCl
2, bentonite, one or more combination in polyethyl acrylate.
Wherein said binding agent is one or more the combination in polyethylene glycol, paste, cellulose, carragheen.
Wherein said defoamer is organosilicon ketone, C
10-20saturated fatty acid and ester, C
14-20saturated monocarboxylic acid and ammonium salt, nonionic and compound thereof, C
8-10one or more combination in aliphatic carboxylic acid and ester class thereof, ester-ether type compound.
Wherein said filler is bentonite, kaolinite, potter's clay.One or more combination in clay, montmorillonite, diatomite, attapulgite.
Wherein said solvent is the one in methyl alcohol, pyrrolidones, fatty alcohol, fatty acid ester, deionized water, cyclohexanone, acetone.
The preparation process of this water dispersible granules adopts extruder grain method.First by former for mandipropamid medicine, the former medicine of polyoxin carries out just pulverizing, by the former medicine after pulverizing, inert carrier, dispersant, wetting agent, disintegrant, part defoamer, filler adds in homogenizer and carries out premixed (particle diameter≤800um), afterwards the pre-composition obtained and residue defoamer are added levigate in airslide disintegrating mill (particle diameter≤100um), by the levigate mixture obtained, deionized water, binding agent adds in kneader simultaneously to be mediated, make the material of shaping, proceed to afterwards in comminutor (130 DEG C) and carry out granulation, anhydrate particle in 50 ~ 60 DEG C of drying boxes a point oven dry 2 ~ 3.5h afterwards, dried granular pattern screening (particle diameter 0.2 ~ 0.5mm), the water dispersible granules of final obtained said composition.
Instant component is reasonable, and bactericidal effect is good, and synergistic effect is remarkable, not only can slow down the generation of resistance, and good to crop safety, meets the security requirement of pesticidal preparations.The present invention has good control efficiency to cucumber downy mildew.
Embodiment
In order to prevent and treat cucumber downy mildew, carried out composite synergy research with mandipropamid and polyoxin, but the present invention is not limited to these examples.Below by embodiment, the present invention is elaborated.
The preparation of embodiment 1:24% mandipropamid Wettable polyoxin powder
1.1 for examination raw material
Accurately take the former medicine 21.51g of mass content 93% mandipropamid; The former medicine 11.76 of mass content 34% polyoxin; Inert carrier is bentonite 10g; Wetting agent is neopelex 2g, lauryl alcohol polyethylene glycol oxide base ether 3g; Dispersant is sodium lignin sulfonate 2g, alkylphenol-polyethenoxy base ether formaldehyde condensate sulfonate 2g; Anticaking agent is sodium silicoaluminate 2.5g; Defoamer organic silicone (280#) 0.3g; Filler talcum powder 44.93g.
1.2 preparation process
Step one: after former for mandipropamid medicine 21.51g, the former medicine 11.76g of polyoxin are ground, then bentonite 10g, neopelex 2g, lauryl alcohol polyethylene glycol oxide base ether 3g, sodium lignin sulfonate 2g, alkylphenol-polyethenoxy base ether formaldehyde condensate sulfonate 2g, sodium silicoaluminate 2.5g, talcum powder 44.93g, 280#0.2g are added stirred tank and carries out premixed 15min in adding.
Step 2 grinds rear mixing: mix (particle diameter≤100um) after above-mentioned premix and 280#0.1g are ground 30min in skin grinder again.
Step 3 is levigate: by decompound levigate 1.5h (particle diameter 1 ~ 20um) in airslide disintegrating mill, carry out mixing for the last time, finally carry out the packing of product.
The preparation of embodiment 2:24% mandipropamid polyoxin water dispersible granules
2.1 for examination raw material
Accurately take the former medicine 21.51g of mass content 93% mandipropamid; The former medicine 11.76g of mass content 34% polyoxin; Inert carrier is bentonite 8g; Soak as sodium lignin sulfonate 4g, naphthalene sulfonic acid-formaldehyde condensation product tower More 2g; Dispersant neopelex 2g; Defoamer is organic silicone (280#) 0.4g; Disintegrant is polyethyl acrylate 3g; Binding agent polyethylene glycol 0.3g; Deionized water 10g; Talcum powder 37.03g.
2.2 preparation process
Step one: after former for mandipropamid medicine 21.51g, the former medicine 11.76g of polyoxin are ground, then bentonite 8g, sodium lignin sulfonate 4g, naphthalene sulfonic acid-formaldehyde condensation product tower More 2g, neopelex 2g, polyethyl acrylate 3g, 280#0.2g, talcum powder 37.03g are added in homogenizer carry out premixed 15min (particle diameter≤800um).
Step 2: said mixture, 280#0.2g are added levigate 30min in airslide disintegrating mill (particle diameter≤100um).
Step 3: will again levigate mixture, deionized water 10g, polyethylene glycol 0.3g add in kneader, mediate 30min, proceeding to temperature be afterwards carry out granulation 60min in the comminutor of 130 DEG C, anhydrate particle in 50 DEG C of drying boxes a point oven dry 2h afterwards.
Step 4: by dried granular pattern screening (particle diameter 0.2 ~ 0.5mm), packaging, the water dispersible granules of final obtained said composition.
The preparation of embodiment 3:24% mandipropamid polyoxin suspending agent
3.1 for examination raw material
Accurately take the former medicine 21.51g of mass content 93% mandipropamid; The former medicine 11.76g of mass content 34% polyoxin; Wetting dispersing agent is sodium lignin sulfonate 2g, naphthalene sulfonic acid-formaldehyde condensation product tower More 2g, neopelex 4g; Defoamer is organic silicone (280#) 0.1g; Thickener is Magnesiumaluminumsilicate 2g, xanthan gum 0.05g; Anti-antifreeze is propane diols 8g, deionized water complements to 47.63g.
3.2 preparation process
Step one is mixing just: former for mandipropamid medicine 21.51g, the former medicine 11.76g of polyoxin, sodium lignin sulfonate 2g, naphthalene sulfonic acid-formaldehyde condensation product tower More 2g, neopelex 4g, propane diols 8g, 280#0.05g, Magnesiumaluminumsilicate 2g, deionized water 25g are pressed design flow and load in high-speed mixer, about 30min fully mixes obtained thick dispersion liquid, proceed to afterwards in ball mill, start ball mill and pulverize 1.5 ~ 2h, sampling detects particle diameter and reaches 200 orders stopping pulverizing.
Step 2 ultramicro grinding: material previous step obtained drops into and is equipped with in the skin grinder of glass sand (1.0 ~ 2.0mm), logical cooling water, add 280#0.05g, xanthan gum 0.05g, deionized water 22.13g, carry out sand milling ultramicro grinding and shear 2.5 ~ 3h (linear velocity 600m/min), final sand milling is particle diameter≤3um, viscosity is the emulsion of 100 ~ 1000mPas.
Step 3 homogeneous mixing preparation: added by material in homogenizer, again process 30 ~ 50min, improves the stability of preparation, the suspending agent of final obtained inventive mixture.
Embodiment 4: according to the method for embodiment 3, can prepare the bactericidal composition suspending agent of the different ratio of mandipropamid and polyoxin
Table 1: the different ratio of mandipropamid and polyoxin makes suspending agent composition
Embodiment 5 mandipropamid and the indoor co-toxicity test of polyoxin.
5.1 reagent agent
The former medicine of 93% mandipropamid (Xian Zhengda crop protection Co., Ltd of Switzerland), the former medicine of 34% polyoxin (Rushan Gold Mine, Shandong Han Wei bio tech ltd).
5.2 strains tested
Bacterium of downy mildew of cucumber is that the separation of agricultural chemicals teaching and research room of Jilin Agriculture University is identified and preserves.
5.3 medicament configurations
According to the result of preliminary experiment, 5 test proportionings will be set, namely mandipropamid and polyoxin are configured to 1:3,1:5,1:1,3:1,5:1 by active ingredient different ratio, are diluted to 25mg/L, 5mg/L, 1mg/L, 0.4mg/L, 0.2mg/L5 concentration respectively for subsequent use by the deionized water of sterilizing.
5.4 test method
Gather blade: the cucumber leaf dish beating cut-off footpath 1.5cm with card punch, the back side is placed in 9cm culture dish upward, and (wet moisturizing on filter paper in bottom, every ware 10 leaf dishes, and every mass concentration repeats 3 wares, amounts to 15 dishes; Move in the culture dish of diameter 9cm with pipettor by the mixture liquid configured, every ware 10mL, blank adds sterilizing deionized water; Swum in upward on liquid at the leaf dish back side, the bacterium of downy mildew of cucumber spore suspension obtained in laboratory with pipettor is seeded to leaf disk center, and 10 μ L/ leaf dishes, are placed in 19 DEG C, cultivates 5-7d under dark alternately 12h condition, the state of an illness on investigation leaf dish.
5.5 result investigation and calculating
Disease index on investigation leaf dish, the percentage accounting for whole leaf disc area according to product spore area divides disease level:
0 grade without scab
1 grade of lesion area accounts for whole leaf disc area less than 5%
3 grades of lesion areas account for whole leaf disc area 6%-10%
5 grades of lesion areas account for whole leaf disc area 11%-25%
7 grades of lesion areas account for whole leaf disc area 26%-50%
9 grades of lesion areas account for whole leaf disc area more than 50%
The formula of disease index and control efficiency is as follows:
Disease index=[∑ (sick leaf dish number × relative level numerical value at different levels)/(investigating total leaf dish number × 9)] × 100
Relative control effect (%)=[(contrast disease index-process disease index)/contrast disease index] × 100
Relative level numerical value---leaf dish onset area relative disease progression
Contrast disease index---unprinted leaf dish scab disease index
Process disease index---dosing leaf dish scab disease index
Adopt DPS software, relative control effect is converted to probit value is ordinate, to convert denary logarithm value to be abscissa to drug concentration, obtain virulence regression equation y=a+bx and correlation coefficient, and calculate the EC of each medicament to downy mildew germ
50value.
5.6 coefficient of synergism computational methods
Adopt Wadley method to carry out co-toxicity evaluation, determine its optimum proportioning.
EC
50(th)＝(a+b)/[a/EC(A)
50+b/EC(B)
50]
Coefficient of synergism (SR)=EC
50(th)/EC
50(ob)
EC
50(ob)---draw the actual EC of mixture in test
50
EC
50(th)---the theoretical EC calculated
50,
A---mandipropamid single dose EC
50,
B---polyoxin single dose single dose EC
50,
The quality ratio of a---mandipropamid shared content in mixture
The quality ratio of b---polyoxin shared content in mixture
The theoretical EC of coefficient of synergism (SR)---mixture
50with actual EC
50ratio
SR>1.5 is synergistic effect, and 0.5≤SR≤1.5 are summation action, and SR<0.5 is antagonism.
Table 2: the indoor co-toxicity result of mandipropamid, polyoxin
As can be seen from Table 1, the bacteriostatic activity difference that the mixture of mandipropamid and polyoxin different ratio shows cucumber downy mildew is obvious, mandipropamid and polyoxin are all better than single dose to the bacteriostatic activity of cucumber downy mildew, EC after 5:1,3:1 mixture in mass ratio
50value is respectively 0.28mg/L, 0.51mg/L, and coefficient of synergism SR is 2.35,1.32, and when wherein mass ratio is 5:1, synergistic effect is remarkable.According to Wadley evaluation assessment, SR > 1.5 is synergistic effect; Mandipropamid and polyoxin in mass ratio 1:1,1:3,1:5 mixing after, coefficient of synergism, between 0.5 ~ 1.5, shows summation action.Suggestion carries out further field control effectiveness test to suitable proportion 5:1 mixture preparation, to evaluate its field practical application effect.
Embodiment 6 mandipropamid and polyoxin are to the field trial of cucumber downy mildew
6.1 test method
Selected place is positioned at Jilin Agriculture University experimental field, and selected experimental field liquid manure is sufficient, and physical features is smooth.Test designs 6 process altogether, repeats for three times, Gong18Ge community, every plot area 30m
2, each community takes random groups to arrange.
6.2 investigation methods and time
Pilot survey is by pesticide field efficacy medicine test criterion (one): bactericidal agent for preventing and treating cucumber downy mildew carries out, after dispenser, 7d carries out cucumber downy mildew incidence survey, diagonal method is adopted to choose 5 strains in community, investigate its whole blade, the percentage accounting for total blade area with each leaf spot lesion area carries out severity Scaling.
Grade scale:
0 grade without scab
1 grade of lesion area accounts for whole leaf area less than 5%
3 grades of lesion areas account for whole leaf area 6%-10%
5 grades of lesion areas account for whole leaf area 11%-25%
7 grades of lesion areas account for whole leaf area 26%-50%
9 grades of lesion areas account for whole leaf area more than 50%
Disease index (%)=[Σ (each grade blade morbidity number × relative level numerical value)/(investigation total leaf number × 9)] × 100
Control efficiency (%)=[(blank disease index-process disease index)/blank disease index] × 100
Table 3: the field test results of each process control cucumber downy mildew
Note: experimental data carries out data difference significance analysis (α=0.05,0.01 is that software is decided at the higher level but not officially announced) through DPS software; A represents remarkable in the level of α=0.05, and b represents variant in the level of α=0.05, and c represents not remarkable in the level of α=0.05; A represents remarkable in the level of α=0.01, and B represents variant in the level of α=0.01, and c represents not remarkable in the level of α=0.01.
The effect of different disposal control cucumber downy mildew is as shown in table 3.Mandipropamid polyoxin suspending agent (SC) has good preventive effect to control cucumber downy mildew, be better than mandipropamid (former medicine) that formulation rate is 150mg/kg and polyoxin (former medicine) and blank, both preventive effects are respectively 82.03%, 62.37%.And 36% mandipropamid polyoxin SC 125,150, under 175mg/kg dosage, preventive effect is respectively 82.48%, 90.27%, 85.45%, and the preventive effect wherein under 150mg/kg dosage is best.Observe through duration of test, plant is compared in blank in dispenser, does not produce symptom of chemical damage, so test medicine is to cucumber growth safety.
In sum, the present invention is the bactericidal composition containing mandipropamid and polyoxin, its active with fungistatic effect compared with existing single dose, not only have and well prevent and kill off cucumber downy mildew effect, and have significant synergistic effect, the generation of pathogen to single dose resistance can be slowed down simultaneously, add biological agent, safety is good, reduces residue of pesticide risk, also meets the security requirement of pesticidal preparations.So research and development of the present invention and popularization are of great significance agriculturally preventing and treating cucumber downy mildew tool.
Claims (5)
1. one kind contains the bactericidal composition of mandipropamid and polyoxin, it is characterized in that: its active ingredient is mandipropamid and polyoxin, all the other are auxiliary element, and auxiliary element is wetting agent, dispersant, disintegrant, defoamer, thickener, antifreezing agent, anticaking agent, filler, binding agent, solvent and inert carrier etc.; The mass ratio of active ingredient mandipropamid and polyoxin is 1:20 ~ 20:1, and the percentage that both mandipropamid and polyoxin account for bactericidal composition gross mass is 1% ~ 80%.
2. a kind of bactericidal composition containing mandipropamid and polyoxin as claimed in claim 1, is characterized in that: bactericidal composition is suspending agent, and by mass percent be 100% calculating, the mass percentage of its component is,
Mandipropamid 2.5 ~ 30%
Polyoxin 2.5 ~ 30%
Wetting agent 2 ~ 4%
Dispersant 4 ~ 6%
Defoamer 0.02 ~ 0.1%
Thickener 0.1 ~ 3%
Antifreezing agent 2 ~ 8%
Deionized water complements to 100%
And the mass ratio of mandipropamid and polyoxin is 1:5 ~ 5:1;
Described wetting agent is one or more the combination in lignosulfite solid content, aliphatic alcohol polyethenoxy base ether, Negel, lignosulfonates, alkylaryl polyoxyethylene ether, lauryl alcohol polyethylene glycol oxide base ether sodium sulfate, alkyl naphthalene formaldehyde condensate sulfonates, fatty alcohol ethylene oxide adduct phosphoric acid salt;
Described dispersant is one or more the combination in alkyl naphthalene formaldehyde condensate sulfonates, fatty alcohol ethylene oxide adduct phosphate, lignosulfonates, polymerization alkylaryl sulfonates, alkylphenol-polyethenoxy base ether formaldehyde condensation products sulphate, Sodium Polyacrylate, alkylphenol-polyethenoxy base phosphate, lignin and derivative desulfonate polycarboxylate thereof, succinic acid, sulfonated ester;
Described defoamer is organosilicon ketone, C
10-20saturated fatty acid and ester, C
14-20saturated monocarboxylic acid and ammonium salt, nonionic and compound thereof, C
8-10one or more combination in aliphatic carboxylic acid and ester class thereof or ester-ether type compound;
Described thickener is one or both combinations in gum Arabic, xanthan gum, polyvinyl alcohol, PVP, disperse silicic acid, carboxymethyl cellulose, polyvinyl acetate, Magnesiumaluminumsilicate, Sodium Polyacrylate, gaseous silicon oxide;
Described antifreezing agent is one or both combinations in ethylene glycol, glycerine, propane diols, glycerine, glycerine-ether diglycol or methyl propylene diglycol.
3. a kind of bactericidal composition containing mandipropamid and polyoxin as claimed in claim 1, is characterized in that: bactericidal composition is wetting powder, and by mass percent be 100% calculating, the mass percentage of its component is,
Mandipropamid 2.5 ~ 30%
Polyoxin 2.5 ~ 30%
Inert carrier 10 ~ 20%
Dispersant 3 ~ 5%
Wetting agent 0.5 ~ 3%
Anticaking agent 1 ~ 3%
Defoamer 0.05 ~ 1%
Filler complements to 100%
And the mass ratio of mandipropamid and polyoxin is 1:5 ~ 5:1;
Described inert carrier is one or more the combination in diatomite, bentonite, attapulgite, potter's clay, kaolin, talcum powder;
Described wetting agent is tea, Chinese honey locust, silkworm excrement, sodium alkyl sulfonate, alkylbenzenesulfonate, alkylnaphthalene sulfonate, aliphatic alcohol sulfate, alkylphenol-polyethenoxy base ether sodium sulfate, phosphate, alkylphosphonic, fatty alcohol ethylene oxide adduct phosphate, dialkyl succinylsuccinate sulfonate, alkyl amide benzene sulfonate, sorbitan fatty acid ester-span, alkyl phenyl polyethylene oxides ether succinate monoester sulfonate, sorbitan fatty acid ester polyoxyethylene ether-twccnm, one or more combination in alkylphenol formaldehyde condensation product polyoxyethylene ether,
Described dispersant is one or more the combination in phosphoric acid ester, phosphate, sulfonate, lignin sulfonate, naphthalenesulfonate, benzenesulfonates, sodium phosphate trimer, calgon, polyvinylpyrrolidone, Sodium Polyacrylate, polyethylene glycol;
Described defoamer is silicone, C
8-C10one or more combination in fatty alcohol, oxirane and propylene oxide block copolymer;
Described anticaking agent is one or more the combination in white carbon, sodium silicoaluminate, silica or tricalcium phosphate;
Described filler is one or more the combination in talcum powder, clay, diatomite, vermiculite, potter's clay, kaolin, attapulgite, white carbon.
4. a kind of bactericidal composition containing mandipropamid and polyoxin as claimed in claim 1, is characterized in that: bactericidal composition is water dispersible granules, and by mass percent be 100% calculating, the mass percentage of its component is,
Mandipropamid 2.5 ~ 30%
Polyoxin 2.5 ~ 30%
Inert carrier 10 ~ 20%
Solvent 10 ~ 15%
Dispersant 2 ~ 5%
Wetting agent 1 ~ 3%
Disintegrant 2 ~ 5%
Binding agent 0.1 ~ 3%
Defoamer 0.01 ~ 0.5%
Filler complements to 100%
And the mass ratio of mandipropamid and polyoxin is 1:5 ~ 5:1;
Described inert carrier is one or more combination in diatomite, bentonite, attapulgite, potter's clay, kaolin;
Described dispersant is one or more the combination in anion surfactant and non-ionic surface active agent; Anion surfactant is phosphoric acid ester, metal carboxylate, lignin sulfonate, polystyrene-based phenol polyethenoxy ether Sulfates, benzenesulfonates or succinic acid salt; Non-ionic surface active agent is fatty alcohol copolymer, macromolecular grafted copolymer, one or more the combination of polystyrene-based phenol polyethenoxy ethers;
Described is wetting. and be one or more the combination in polystyrene-based polyethenoxy ether class, polyoxyethylene nonylphenol ether class, alkyl naphthalene sulfonic acid salt and fatty alcohol polyethenoxy ether class;
Described disintegrant is ammonium sulfate, anhydrous sodium sulfate, CaCl
2, bentonite, one or more combination in polyethyl acrylate;
Described binding agent is one or more the combination in polyethylene glycol, paste, cellulose, carragheen;
Described defoamer is organosilicon ketone, C
10-20saturated fatty acid and ester, C
14-20saturated monocarboxylic acid and ammonium salt, nonionic and compound thereof, C
8-10one or more combination in aliphatic carboxylic acid and ester class thereof, ester-ether type compound;
Described filler is bentonite, kaolinite, potter's clay.One or more combination in clay, montmorillonite, diatomite, attapulgite;
Described solvent is the one in methyl alcohol, pyrrolidones, fatty alcohol, fatty acid ester, deionized water, cyclohexanone, acetone.
5. a kind of bactericidal composition containing mandipropamid and polyoxin that Claims 1 to 4 is narrated is preventing and treating the application in cucumber downy mildew.
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| CN201510916731.5A CN105340926A (en) | 2015-12-11 | 2015-12-11 | Bactericidal composition containing mandipropamid and polyoxins and application of bactericidal composition |
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Cited By (1)
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| CN114349569A (en) * | 2021-01-26 | 2022-04-15 | 广西壮族自治区农业科学院 | Ecological conditioning type fertilizer special for eucalyptus and preparation method thereof |
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