CN1053374C - Chinese-medicinal oral liquor for curing coronary heart disease and angina pectoris and preparing method - Google Patents
Chinese-medicinal oral liquor for curing coronary heart disease and angina pectoris and preparing method Download PDFInfo
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- CN1053374C CN1053374C CN96115634A CN96115634A CN1053374C CN 1053374 C CN1053374 C CN 1053374C CN 96115634 A CN96115634 A CN 96115634A CN 96115634 A CN96115634 A CN 96115634A CN 1053374 C CN1053374 C CN 1053374C
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- shuangdan
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Abstract
The present invention relates to Shuangdan oral medicinal liquid which is a traditional Chinese medicine preparation for curing coronary heart disease and angina pectoris, and a preparation method of the Shuangdan oral medicinal liquid. The present invention is characterized in that the Shuangdan oral medicinal liquid with the efficacy of activating blood circulation to dissipate blood stasis, removing obstruction in collaterals and relieving pain is prepared from red sage root, tree peony bark, honey, etc. The Shuangdan oral medicinal liquid is mainly used for curing coronary heart disease and angina pectoris caused by heart blood stasis obstruction, the total effective rate is 93.6% in clinical therapy, and the total effective rate for improving various symptoms of the obstruction of Qi in chest, such as thoracalgia, chest distress, palpitation, short breath, hypodynamia, the cyanosis of the mouth and lip, etc., reaches more than 86%; the Shuangdan oral medicinal liquid also has the function of lowering blood pressure; the Shuangdan oral medicinal liquid which has no adverse reactions after being proved by clinical observation and can take effect quickly is a novel medicine with a high curative effect on coronary heart disease and angina pectoris.
Description
The invention belongs to a kind of Chinese medicine preparation, especially treat coronary heart disease and anginal oral liquid (also claiming SHUANGDAN KOUFUYE).
At present, coronary heart disease, angina pectoris are commonly encountered diseases, frequently-occurring disease clinically, and sickness rate rises year by year, are the principal diseases that threatens human body health, traditional Chinese medicine in treatment based on blood circulation promoting and blood stasis dispelling, removing obstruction in the collateral to relieve pain etc.At present treatment coronary heart disease, anginal Chinese patent medicine are more, but prescription is big, and flavour of a drug are many, and curative effect is not fairly obvious.
The purpose of this invention is to provide a kind of treatment coronary heart disease, anginal quick-acting, Chinese medicine oral liquid efficiently.The present invention utilizes Radix Salviae Miltiorrhizae stasis-dispelling and pain-killing, promoting blood circulation to restore menstrual flow, and the relieving restlessness that clears away heart-fire is aided with the effect of Cortex Moutan clearing away heat and cooling blood, hypertensive tranquilizing.Pharmacodynamics shows that the present invention can obviously prolong the mice normal pressure anoxia enduring time-to-live, but the ischemic ECG change due to the antagonism pituitrin; Can significantly reduce the myocardial infarction area that ligation heart branch of coronary artery is caused, the myocardium weight of infarct is obviously reduced; And the remarkable microcirculation disturbance that caused of antagonism pituitrin, and hypotensive effect is preferably arranged.
SHUANGDAN KOUFUYE of the present invention and preparation method thereof: it is characterized in that producing 1000 milliliters of SHUANGDAN KOUFUYE, required pharmaceutical formulation contains Radix Salviae Miltiorrhizae 550-650 gram, Cortex Moutan 250-350 gram, Mel 130-170 gram, sodium benzoate 2-3 gram.Process for preparing medicine: after Cortex Moutan distilled paeonol, medicinal residues and Radix Salviae Miltiorrhizae decocted with water secondary together, and 2 hours for the first time, 1 hour for the second time, to filter, filtrate concentrates, and concentrated solution adds ethanol makes pure content reach 60%, cold preservation (2 ℃-2 ℃) 24 hours; Filter, reclaim ethanol to most; Filter, add water-cooled and hid (2-2 ℃) 48 hours; Filter, add the Cortex Moutan distillate, add Mel, sodium benzoate, fill, sterilization.
Using method of the present invention: every day secondary, each 20 milliliters, 28 days is a course of treatment, takes for a long time, has no side effect.1
Characteristics of the present invention and effect: SHUANGDAN KOUFUYE of the present invention has the effect of blood circulation promoting and blood stasis dispelling, removing obstruction in the collateral to relieve pain.Clinically cure mainly coronary heart disease due to the stagnation of heart-blood, angina pectoris, and good hypotensive effect is arranged.Show through three tame hospital clinical observed results, SHUANGDAN KOUFUYE treatment coronary heart disease total effective rate of the present invention is 93.6%, clinical obvious effective rate is 49.6%, to anginal total effective rate is 91.8%, clinical obvious effective rate is 45.9%, to the Electrocardiographic total effective rate of ischemic is 55.6%, clinical obvious effective rate is 17.8%, and can obviously improve thoracic obstruction blood stasis type patient's hemorheology whole blood viscosity, plasma viscosity, many indexs such as packed cell volume, to improving the every disease of the thoracic obstruction, chest pain, uncomfortable in chest, cardiopalmus, shortness of breath and fatigue, total effective rates such as die Blausucht reach more than 86%, in the clinical observation process, do not see untoward reaction, safe in utilization, be a kind of good curing coronary heart disease, anginal new drug.
Embodiment:
Get Radix Salviae Miltiorrhizae 550 grams, Cortex Moutan 250 grams place Cortex Moutan in the extraction pot, the water that adds 10 times, vapor distillation, distillate device are in addition placed, medicinal residues and Radix Salviae Miltiorrhizae decoct with water secondary, 2 hours for the first time, 1 hour for the second time, filter, filtrate concentrates, concentrated solution adds ethanol, makes pure content reach 60%, Cryoprecipitation jar Cryoprecipitation 24 hours (2-2 ℃); Filter, reclaim ethanol to most; Add the entry water precipitating 48 hours (2-2 ℃); Filter, add the Cortex Moutan distillate, add Mel 150 grams, sodium benzoate 3 grams, add water to 1000 milliliters, stir evenly, fill, sterilization, SHUANGDAN KOUFUYE of the present invention.2
Claims (1)
1. treatment coronary heart disease and anginal oral liquid is characterized in that getting Radix Salviae Miltiorrhizae 550-650 gram, Cortex Moutan 250-350 gram, Mel 130-170 gram, sodium benzoate 2-3 gram; After Cortex Moutan distilled paeonol, medicinal residues and Radix Salviae Miltiorrhizae decocted with water secondary together, and 2 hours for the first time, 1 hour for the second time, to filter, filtrate concentrates, and concentrated solution adds ethanol made pure content reach 60% ,-2 ℃ of-2 ℃ of cold preservations 24 hours; Filter, reclaim ethanol to most; Filter, add water-cooled at-2-2 ℃ and hid 48 hours; Filter, add the Cortex Moutan distillate, add Mel, sodium benzoate, fill, sterilization, make the 1000ml oral liquid altogether.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN96115634A CN1053374C (en) | 1996-02-01 | 1996-02-01 | Chinese-medicinal oral liquor for curing coronary heart disease and angina pectoris and preparing method |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN96115634A CN1053374C (en) | 1996-02-01 | 1996-02-01 | Chinese-medicinal oral liquor for curing coronary heart disease and angina pectoris and preparing method |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1156047A CN1156047A (en) | 1997-08-06 |
| CN1053374C true CN1053374C (en) | 2000-06-14 |
Family
ID=5122865
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN96115634A Expired - Fee Related CN1053374C (en) | 1996-02-01 | 1996-02-01 | Chinese-medicinal oral liquor for curing coronary heart disease and angina pectoris and preparing method |
Country Status (1)
| Country | Link |
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| CN (1) | CN1053374C (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100337654C (en) * | 2005-08-01 | 2007-09-19 | 浙江大学 | Composition of Chinese medicine effective ingredients for treating cardiovascular disease |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2000272667A1 (en) | 2000-09-13 | 2002-04-29 | Jiangsu Kanion Pharmaceutical Co. | Pharmaceutical composition treating gynecological blood stasis diseases, cardio and cerebral vascular diseases, respiratory diseases and the like |
| CN100370973C (en) * | 2005-07-08 | 2008-02-27 | 叶耀良 | Traditional Chinese medicinal prepn. for treating obstruction of qi in the chest |
| CA2659442C (en) | 2006-10-18 | 2015-12-22 | Jiangsu Kanion Pharmaceuticals, Co. Ltd. | Cinnamomi and poria composition and uses thereof |
| CN108175783A (en) * | 2018-02-26 | 2018-06-19 | 潘秀华 | Treat the Traditional Chinese medicine lozenge of hypertension |
| CN108143783A (en) * | 2018-02-26 | 2018-06-12 | 潘秀华 | A kind of preparation method for the Traditional Chinese medicine lozenge for treating hypertension |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1073205A (en) * | 1991-12-14 | 1993-06-16 | 张洪林 | The prescription of compound red-rooted salvia wine and production method |
-
1996
- 1996-02-01 CN CN96115634A patent/CN1053374C/en not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1073205A (en) * | 1991-12-14 | 1993-06-16 | 张洪林 | The prescription of compound red-rooted salvia wine and production method |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100337654C (en) * | 2005-08-01 | 2007-09-19 | 浙江大学 | Composition of Chinese medicine effective ingredients for treating cardiovascular disease |
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| Publication number | Publication date |
|---|---|
| CN1156047A (en) | 1997-08-06 |
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