CN105325794A - Health food and preparation method thereof - Google Patents
Health food and preparation method thereof Download PDFInfo
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- CN105325794A CN105325794A CN201410391173.0A CN201410391173A CN105325794A CN 105325794 A CN105325794 A CN 105325794A CN 201410391173 A CN201410391173 A CN 201410391173A CN 105325794 A CN105325794 A CN 105325794A
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Abstract
The invention relates to the field of biological medicine and discloses a health food and a preparation method thereof. The health food comprises the following substances by weight: 4 to 8 parts of wolfberry, 3 to 8 parts of chrysanthemum, 4 to 10 parts of haw, 2 to 6 parts of sharpleaf galangal fruit and 4 to 10 parts of white peony root. The health food is developed through combination of traditional Chinese medicine treatment based on syndrome differentiation and newest modern scientific research achievements. The invention also provides a preparation method for the health food. The health food provided by the invention can effectively improve asthenopia, enhance distant vision and duration of clear vision, is convenient, safe and reliable to eat, low in price, applicable to teenagers or people using computers for a long time and suitable for long-term eating, and incurs no adverse reaction. Equipment used in the preparation method is simple; cost is low; and industrial production can be realized.
Description
Technical field
The present invention relates to biomedicine field, particularly relate to health food of a kind of alleviating asthenopia and preparation method thereof.
Background technology
Along with the development of society and the change of people life style, excess eye-using becomes universal phenomenon.China's myopia incidence is about 27%, world rankings the second, and especially in children and teenager, illness rate is higher.Therefore, the health products with alleviating asthenopia become the effective measure of the disease of eye such as prevention and control myopia, farsightedness, and the market demand is very big.Visual fatigue is the modal a kind of disease of current ophthalmology, and the symptom of patient is varied, and common are near work can not be lasting, and pain around eyes and eye socket, blurred vision, eyes are dry and astringent, shed tears, severe patient headache, feel sick, dizzy.It is not independently disease, but the one group of fatigue syndrome caused due to a variety of causes.Its occurrence cause is also varied, common are: the reason of (l) eyes itself, as myopia, long sight, astigmatism, conjunctivitis, keratitis etc.; (2) systemic factor, as neurasthenia, health overwork, hysteria or climacteric; (3) environmental factor, as illumination is not enough or excessively strong, distribution of light sources is uneven or glimpse, and the target of watching attentively is too small, meticulous or unstable.
The main composition of alleviating asthenopia is beta carotene, vitamin A, Pfansteihl zinc, LBP-X, Puerarin, lutein, zeaxanthin, vitamin E, vitamin C, selenium, zinc etc.
Matrimony vine: matrimony vine is containing LBP-X, fat, protein, free amino acid, taurine, betaine (betaine), vitamin B1, vitamin B2, vitamin E and vitamin C; carotenoid content is very high, also containing a large amount of mineral matter potassium, sodium, calcium, magnesium, iron, copper, manganese, zinc, selenium etc.Cure mainly nourishing liver and kidney, benefiting shrewd head.Lose for consumptive disease essence, soreness of waist and knee joint, dizzy tinnitus, interior heat is quenched one's thirst, and the deficiency of blood is sallow, and blurred vision is failed to understand.What treatment deficiency of liver-blood, deficiency of kidney-YIN caused looks thing duskization and yctalopia, usually uses matrimony vine.
Chrysanthemum: chrysanthemum is mainly containing volatile oil, adenine, choline, stachydrine, chrysanthemum glucoside, amino acid, flavonoids and mcg vitamin B1.Volatile oil is containing borneol, camphor, chrysanthenone etc.Flavonoids has cyanidenon-7-glycoside, cosmosiin, acaciin, aminozide etc.Its nature and flavor are sweet, bitter, are slightly cold.Enter lung, Liver Channel.There is dispelling wind and heat from the body, improving eyesight, clearing heat and detoxicating, the effect of flat liver.Be mainly used in affection of exogenous wind-heat, heating, aversion to cold, headache and red eye, swell pain.Chrysanthemum controls red eye, swell pain, and no matter belong to irascibility or wind-heat causer, all can apply, as deficiecny of liver-YIN, eyes is dim-sighted, same with the effect having synergy with matrimony vine.
The present invention is on existing theory of traditional Chinese medical science basis, natural drug and some nutrients is adopted to be formed by scientific compatibility, play each component mutually to act synergistically, wolfberry bright eye effect is utilized to make medlar tea bag, matrimony vine tablet, granule or capsule in conjunction with the medicine that other have alleviating asthenopia, instant, effect is remarkable.
Summary of the invention
The invention provides a kind of health food of alleviating asthenopia.Described health food comprises the material of following parts by weight: matrimony vine 4-8 part, chrysanthemum 3-8 part, hawthorn 4-10 part, fructus alpiniae oxyphyllae 2-6 part, root of herbaceous peony 4-10 part.
Health food of the present invention can also comprise auxiliary material 0.1-20 part.
In the present invention, described accessory package contains acceptable auxiliary material in bromatology, thus can be made into various formulation, as tablet, granule or capsule etc.
Raw material also directly can be packed into tea in bag by health food of the present invention.
In the present invention, described auxiliary material can be selected from the one or more kinds of combinations in Fruit powder, flavoring essence, sweetener, acid, filler, lubricant, food coloring.Wherein, Fruit powder comprises orange powder, lemon powder, cherry powder, apple powder and coconut palm powder; Flavoring essence comprises orange essence, lemon extract, cherry essence, flavoring apple essence and cocoanut flavour; It is sweet that sweetener comprises Sucralose, 3,4-Dihydro-6-methyl-1,2,3-oxathiazin-4-one 2,2-dioxide potassium salt, Aspartame, mogroside and knob; Acid comprises citric acid, malic acid, lactic acid and citric acid; Filler comprises fructose, glycitols, sucrose, starch and dextrin; Lubricant comprises talcum powder, dolomol, silica and stearic acid; Food coloring comprises burnt sugar coloring, gardenia yellow, curcumin and chlorophyll.
A kind of preparation method of the health food of alleviating asthenopia of the present invention is as follows:
Each component is dried to water content and is less than 4% (weight), be directly packaged into tea in bag by each component compatibility.
More specifically, described preparation method is as follows:
Each component is dried to water content and is less than 4% (weight), by each material disintegrating, cross 40 mesh sieves, mixing, on infrared drying oven, at 60 DEG C, dry disinfection 30min, is packaged into 5g/ bag.
The another kind of preparation method of the health food of alleviating asthenopia of the present invention is as follows:
Get the matrimony vine of suitable compatibility amount, chrysanthemum, hawthorn, fructus alpiniae oxyphyllae, the root of herbaceous peony, add pure water according to the mass ratio of 1:10 and decoct 3 times, first time decocts 2h, and second time decocts 1h, and third time decocts 0.5h, merge decoction liquor, filter, filtrate obtains extract dry powder through freeze drying, and dry powder is through pulverizing, cross 80 mesh sieves and become extract dry powder, make tablet, granule or capsule by distinct methods.
Particularly, in order to make granule, described method also comprises:
Get described extract dry powder, add the suitable dextrin of gross weight 10%, the mogroside of 10%, mixing, uses 80% alcohol granulation, dry, whole grain, and pack, is prepared into granule.
Particularly, in order to make tablet, described method also comprises:
Get described extract dry powder, add the starch mixing of suitable gross weight 10%, use 80% alcohol granulation, dry, whole grain, carries out compressing tablet in tablet press machine, is prepared into tablet.
Particularly, in order to make capsule, described method also comprises:
Get described extract dry powder, add the starch mixing of suitable gross weight 10%, use 80% alcohol granulation, dry, whole grain, then the dolomol mixing adding obtained particle weight 0.4%, encapsulated, be namely prepared into capsule.
The health food of a kind of alleviating asthenopia of the present invention, the basis of traditional tcm syndrome differentiation and treatment forms through scientific compatibility, and all raw materials are taken at nature, it is natural, safe and reliable to come from, and raw material sources are extensively easy to get.By finding normal individual trial experiment, this product has good function of relieving visual fatigue, without any side effects, is very applicable to teenager or Long-Time Service computer person, suitable long-term taking.And involved equipment is simple, cost is lower, can realize suitability for industrialized production.
Beneficial effect of the present invention is:
Health food of the present invention shows can significantly improve visual fatigue symptom through people's test-meal experiment, and the effect of alleviating asthenopia is fine.
The present invention selects that have can the Chinese herbal medicine of remarkable alleviating asthenopia, forms, thus ensure effect of its alleviating asthenopia through scientific matching, and edible safety.For the character of raw material, adopt rational extraction process, its active ingredient is farthest retained.This flow process is succinct, practical, is applicable to big or middle large-scale production.
Detailed description of the invention
Describe health food of the present invention and preparation method thereof in detail below by specific embodiment, following embodiment is only exemplary, not should be understood to limiting the scope of the invention.
Embodiment 1: the preparation of health food tea in bag
Matrimony vine 4 parts, chrysanthemum 4 parts, hawthorn 4 parts, fructus alpiniae oxyphyllae 2 parts, the root of herbaceous peony 4 parts, mixing, in 60 DEG C of vacuum drying to water content within 4%.Pulverize, cross 40 mesh sieves, mixing, on infrared drying oven, (60 DEG C) dry disinfection 30min, is packaged into the tea in bag of 5g/ bag.
Embodiment 2: the preparation of health food extract dry powder
Matrimony vine 4 parts, chrysanthemum 4 parts, hawthorn 4 parts, fructus alpiniae oxyphyllae 2 parts, the root of herbaceous peony 4 parts, mixing, main material gross mass is added pure water according to the mass ratio of 1:10 and decocts 3 times, first time decocts 2h, and second time decocts 1h, third time decocts 0.5h, merge decoction liquor, filter, filtrate obtains extract dry powder through freeze drying, dry powder, through pulverizing, is crossed 80 mesh sieves and is become extract dry powder.
Embodiment 3: the preparation of health food granule
Get the extract dry powder made according to embodiment 2, add the suitable dextrin of gross weight 10%, the mogroside of 10%, mixing, uses 80% alcohol granulation, dry, whole grain, and pack (every bag of 3g), is namely prepared into granule.
Embodiment 4: the preparation of health caring food tablet
Get the starch mixing that the extract dry powder made according to embodiment 2 adds suitable gross weight 10%, use 80% alcohol granulation, dry, whole grain, carries out compressing tablet in tablet press machine, is namely prepared into tablet.
Embodiment 5: the preparation of health-care edible capsule
Get the starch mixing that the extract dry powder made according to embodiment 2 adds suitable gross weight 10%, use 80% alcohol granulation, dry, whole grain, then the dolomol mixing adding obtained particle weight 0.4%, encapsulated, be namely prepared into capsule.
Embodiment 6: the preparation of health food
Main raw materials in proportion: matrimony vine 8 parts, chrysanthemum 8 parts, hawthorn 10 parts, fructus alpiniae oxyphyllae 6 parts, the root of herbaceous peony 10 parts.
Preparation method of teabag is with embodiment 1.
The preparation method of extract dry powder, granule, tablet, capsule is with embodiment 2-5.
Embodiment 7: the preparation of health food
Main raw materials in proportion: matrimony vine 5 parts, chrysanthemum 3 parts, hawthorn 6 parts, fructus alpiniae oxyphyllae 5 parts, the root of herbaceous peony 8 parts.
Preparation method of teabag is with embodiment 1.
The preparation method of extract dry powder, granule, tablet, capsule is with embodiment 2-5.
Test example 1: toxicological test
Granule in Example 3, carries out Toxicological evaluation test according to the Ministry of Public Health's " health food inspection and assessment technical specification " (2003 editions) pertinent regulations.
1) acute through button toxicity test: 90g/kg to be greater than to the large mouse median lethal dose (LD50) of male and female, a maximum tolerated dose (MTD) is greater than 32g/kg, belong to nontoxic level.
2) three genetic toxicity test: Ames experiments, the nuclear test of bone marrow cells in mice dimension and mouse inbred strain results are feminine gender.
3) within 30 days, experiment is fed: do not feed (100,50,25 times relative to people's recommended intake) rat 30 days according to high, medium and low three dosage component, experimental session, animal growth is good, the indexs such as each dosage group body weight, weightening finish, routine blood test, blood biochemistry compared with the control, have no notable difference, illustrate that this granules in rats has no obvious toxic-side effects.
The result that the health food using embodiment 6,7 to prepare carries out toxicological test is substantially identical with the result of the granule in embodiment 3.
Test example 2: functional trial
Alleviating asthenopia human experiment experimental evaluation method according to Ministry of Public Health's " health food inspection and assessment technical specification " (2003 editions) is evaluated.
1, experimenter
Voluntary participation experimenter 60 people, is divided into treatment group and control group at random, control group 30 people, male 13 people, female 17 people, age 21-45 year; Treatment group 30 people, male 16 people, female 14 people, age 20-42 year.
2, selected condition
Visual fatigue patient, has that eye is swollen, the dry and astringent symptom of ophthalmodynia, photophobia, blurred vision and eye.
3, test material
Tablet described in embodiment 4.
4, methods for the treatment of
Treatment group: oral Tablets, every day 2 times, each 1, takes 1 month.
Control group: OP (outward appearance, taste and treatment group similar), every day 2 times, each 1, take 1 month.
5, detection method
Carry out eyesight, cracking lamp, ophthalmoscope, blood, routine urianlysis before all experimenters take, after taking a course for the treatment of, repeat above-mentioned every inspection.Before and after all experimenters take, respectively eye symptom is registered, judge with visual fatigue symptom determination methods (sxemiquantitative integration method), namely with without (0), light (1), in (2), heavy (3) carry out classification, and add up with integrated value.
6, result
1) control group and treatment group symptom integral compare
Compare before and after treatment group treatment and there is significant difference (P<0.05), before and after treatment of control group, compare there was no significant difference (P>0.05); Take front treatment group and control group compares there was no significant difference (P ﹥ 0.05); Take rear treatment group and control group compares significant difference (P<0.05), result is as shown in table 1.
Table 1 clinical symptoms integral contrast
2) control group and treatment group symptom effect compare
Treatment group cures number man 5 example, female 4 example, add up to 9 examples, cure rate adds up to 30%, improve number man 4 example, female 6 example, improvement rate is 33.3%, significant figure man 5 example, female 3 example, efficient is 26.7%, adds up to effectively above ratio to reach 90%, describes this health food and have good efficacy of relieving visual fatigue.Invalid number man 2 example, female 1 example, add up to 3 examples, inefficiency is 10%.The upper indifference of experimental result gender.
The improvement of table 2 clinical symptoms is compared
The result that the health food using embodiment 6,7 to prepare carries out functional trial is substantially identical with the result of the tablet in embodiment 4.
Above content is in conjunction with concrete embodiment further description made for the present invention, can not assert that specific embodiment of the invention is confined to these explanations.For general technical staff of the technical field of the invention, without departing from the inventive concept of the premise, some simple deduction or replace can also be made.
Claims (8)
1. a health food, is characterized in that, comprises the material of following parts by weight: matrimony vine 4-8 part, chrysanthemum 3-8 part, hawthorn 4-10 part, fructus alpiniae oxyphyllae 2-6 part, root of herbaceous peony 4-10 part.
2. health food according to claim 1, is characterized in that, the formulation of described health food is tea in bag, tablet, granule or capsule.
3. prepare a method for the health food described in claim 1 or 2, it is characterized in that, each component is dried to water content and is less than 4%(weight), be directly packaged into tea in bag by each component compatibility.
4. the preparation method of health food according to claim 3, is characterized in that, each component is dried to water content and is less than 4%(weight), by each material disintegrating, cross 40 mesh sieves, mixing, on infrared drying oven, at 60 DEG C, dry disinfection 30min, is packaged into 5g/ bag.
5. prepare a method for the health food described in claim 1 or 2, it is characterized in that, described method comprises:
Get the matrimony vine of suitable compatibility amount, chrysanthemum, hawthorn, fructus alpiniae oxyphyllae, the root of herbaceous peony add pure water according to the mass ratio of 1:10 and decoct 3 times, first time decocts 2h, second time decocts 1h, third time decocts 0.5h, merge decoction liquor, filter, filtrate obtains extract dry powder through freeze drying, dry powder, through pulverizing, is crossed 80 mesh sieves and is become extract dry powder for subsequent use.
6. method according to claim 5, is characterized in that, described method also comprises:
Get described extract dry powder, add the suitable dextrin of gross weight 10%, the mogroside of 10%, mixing, uses 80% alcohol granulation, dry, whole grain, and pack, is prepared into granule.
7. method according to claim 5, is characterized in that, described method also comprises:
Get described extract dry powder, add the starch mixing of suitable gross weight 10%, use 80% alcohol granulation, dry, whole grain, carries out compressing tablet in tablet press machine, is prepared into tablet.
8. method according to claim 5, is characterized in that, described method also comprises:
Get described extract dry powder, add the starch mixing of suitable gross weight 10%, use 80% alcohol granulation, dry, whole grain, then the dolomol mixing adding obtained particle weight 0.4%, encapsulated, be namely prepared into capsule.
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| CN201410391173.0A CN105325794A (en) | 2014-08-08 | 2014-08-08 | Health food and preparation method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN109619479A (en) * | 2018-12-21 | 2019-04-16 | 河南科高中标检测技术有限公司 | A kind of haw products and preparation method thereof with alleviation visual fatigue |
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