CN105309496A - Chinese herbal medicine disinfectant - Google Patents
Chinese herbal medicine disinfectant Download PDFInfo
- Publication number
- CN105309496A CN105309496A CN201410365816.4A CN201410365816A CN105309496A CN 105309496 A CN105309496 A CN 105309496A CN 201410365816 A CN201410365816 A CN 201410365816A CN 105309496 A CN105309496 A CN 105309496A
- Authority
- CN
- China
- Prior art keywords
- parts
- carrying
- liquid
- chinese
- herbal medicine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Abstract
The invention relates to a Chinese herbal medicine disinfectant which can be used for cleaning and disinfecting vegetables, fruits and tableware. Main raw materials of the Chinese herbal medicine disinfectant are prepared according to the following weight ratio: 15 parts of Chinese honeylocust fruits, 15 parts of fresh herba portulacae, 20 parts of artemisia argyi, 20 parts of forsythia fruit, 20 parts of radix scutellariae, 10 parts of rhizoma coptidis, 15 parts of lonicera japonica, 12 parts of herba euphorbiae humifusae, 30 parts of dandelions, 15 parts of oriental wormwood, 15 parts of folium pyrrosiae and 30 parts of flos chrysanthemi indici. The Chinese herbal medicine disinfectant is prepared through the steps of crushing the main raw materials into powder, carrying out pressurized solvent extraction, carrying out pressure filtration so as to obtain liquid, adding an ethanol aqueous solution, of which the volume is 3-5 times that of filtrated residue, into the filtrated residue, carrying out pressurized solvent extraction twice continuously so as to obtain liquid, uniformly mixing the liquids, obtained through carrying out extracting in three times, then, carrying out settling high-speed centrifugal filtration so as to obtain filtrate, subjecting the filtrate, obtained through settling high-speed centrifugal filtration, to ultrafiltration-process filtration so as to obtain filtrate, heating the filtrate to evaporate alcohol, carrying out concentrating so as to obtain a concentrated solution, loading the concentrated solution to brown glass bottles or light-tight plastic bottles, adding a peppermint-oil alcoholic solution into the concentrated solution according to the ratio of 1mL/L, and finally, carrying out bottling and sealing.
Description
Technical field
The present invention relates to a kind of Chinese-herb disinfectant.
Background technology
On market, thimerosal is mostly chemosterilant, and chemosterilant easily allows bacterium produce drug resistance.Minority is exclusively used in veterinary antibiotics, the Chinese herbal disinfectant of table-ware disinfection can not extensively sterilization, and bactericidal effect is poor.In Chinese herbal disinfectant, the comparatively effective thimerosal of minority contains the composition to human body toxic side effect, if enter human body, will work the mischief.The Chinese-herb disinfectant that the present invention relates to can not only kill malignant bacteria effectively, and has no side effect.The primary raw material wide material sources that the present invention relates to, cheap, can large scale investment produce, further the value of exploitation Common Medicinal Herbs.
Summary of the invention
For solving the deficiencies in the prior art, the invention provides a kind of compatibility and compound method of Chinese-herb disinfectant, its primary raw material is prepared according to following weight ratio: Chinese honey locust 15-50 part, fresh purslane 15-30 part, wormwood 20-25 part, capsule of weeping forsythia 15-25 part, root of large-flowered skullcap 15-25 part, coptis 5-10 part, honeysuckle 15-30 part, wolf's milk 10-15 part, dandelion 10-30 part, oriental wormwood 15-30 part, pyrrosia lingua 15-20 part, mother chrysanthemum 20-30 part.
As a further improvement on the present invention, its primary raw material is prepared according to following weight ratio: Chinese honey locust 15 parts, fresh purslane 15 parts, wormwood 20 parts, the capsule of weeping forsythia 20 parts, the root of large-flowered skullcap 20 parts, the coptis 10 parts, honeysuckle 15 parts, wolf's milk 12 parts, dandelion 30 parts, oriental wormwood 15 parts, pyrrosia lingua 15 parts, mother chrysanthemum 30 parts.
The present invention also provides the compound method of described Chinese-herb disinfectant: be ground into raw materials used process of sieving after particle diameter is less than the powder of 50 microns respectively, put one Homogeneous phase mixing in a vessel; Powder after process is put into ethanol water, and isolated air pressurized, to several atmospheric pressure, is heated to liquid boiling, and constantly stir, keep 3 hours, press filtration obtains liquid simultaneously; After press filtration, the residue obtained 3-5 of adding a times ethanol water proceeds pressurized liquid extraction, 2 times repeatedly, three times is extracted the mixing of gained uniform liquid; By the liquid after Homogeneous phase mixing by the elimination removal of impurity of sedimentation high speed centrifugation and precipitation; Liquid after sedimentation high speed centrifugation filter process is removed the material of the macromolecule such as protein and polysaccharide by ultrafiltration, wherein milipore filter molecular weight cut off should between 2000 to 10000; Liquid after Treatment with Ultrafiltration is put into the container of band blast pipe, blast pipe is loaded with condensate collection device, heating evaporation ethanol, continues concentrated liquid and obtains concentrate; Reclaim the ethanol in condensate collection device, solution to be concentrated cool to room temperature, loads Brown Glass Brown glass bottles and jars only or opaque-plastic bottle, adds peppermint oil alcoholic solution, seal at once to concentrate according to 1mL/L by concentrate.
Provide below of the present invention one implement convenient: take Chinese honey locust 15 grams, fresh purslane 15 grams, wormwood 20 grams, the capsule of weeping forsythia 20 grams, the root of large-flowered skullcap 20 grams, the coptis 10 grams, honeysuckle 15 grams, wolf's milk 12 grams, dandelion 30 grams, oriental wormwood 15 grams, pyrrosia lingua 15 grams, mother chrysanthemum 30 grams be ground into last process of sieving respectively, put into same container one Homogeneous phase mixing; Volume fraction powder after Homogeneous phase mixing being put into 4L is the ethanol water of 70%, is forced into two atmospheric pressure, is heated to liquid boiling, constantly stir simultaneously after isolated air, keeps crossing press filtration after 3 hours and obtains liquid; Proceed pressurized liquid extraction to the residue obtained 3-5 of adding of a press filtration times ethanol water, 2 times repeatedly, three times are extracted the mixing of gained uniform liquid; By mixed liquid by the elimination removal of impurity of sedimentation high speed centrifugation and precipitation; Liquid after the filter of sedimentation high speed centrifugation is removed the invalid components such as protein and polysaccharide by ultrafiltration, and wherein milipore filter molecular weight cut off is 5000; By the container of the liquid after Treatment with Ultrafiltration by band blast pipe, blast pipe end is loaded with condensate collection device, is heated to 80 degrees Celsius, until liquid volume is 1L; Reclaim the ethanol in condensate recycling device, concentrate is loaded Brown Glass Brown glass bottles and jars only or opaque-plastic bottle, add peppermint oil alcoholic solution to concentrate according to 1mL/L, seal at once.Peppermint oil alcoholic solution of the present invention is that peppermint oil and alcohol stir gained according to after volume ratio 1:1 mixing.
Provide the experimental result of the Chinese-herb disinfectant that the present invention relates to below: in order to test the bactericidal effect of this Chinese-herb disinfectant, we have employed scraps of paper agar method and do bacteriostatic test.On same White staphylococcus agar medium, streptomycin inhibition zone diameter is 25mm, and gentamicin inhibition zone diameter is 27mm, and the Chinese-herb disinfectant inhibition zone diameter that the present invention relates to is 21mm, and certain brand liquid detergent inhibition zone diameter is 13mm; On same bl plate agar medium, streptomycin inhibition zone diameter is 15mm, and gentamicin inhibition zone diameter is 26mm, and the Chinese-herb disinfectant inhibition zone diameter that the present invention relates to is 22mm, and certain brand liquid detergent inhibition zone diameter is 12mm; On same staphylococcus aureus agar medium, streptomycin inhibition zone diameter is 24mm, and gentamicin inhibition zone diameter is 25mm, and the Chinese-herb disinfectant inhibition zone diameter that the present invention relates to is 19mm, and certain brand liquid detergent inhibition zone diameter is 10mm.Experiment proves, the bactericidal effect of the Chinese-herb disinfectant that the present invention relates to is higher than common liquid detergent, and bactericidal effect is better.With the Chinese-herb disinfectant cleaning tableware that the present invention relates to, discovery can comparatively easily wash residue and greasy dirt off.
In order to test the toxic and side effect of this Chinese-herb disinfectant to animal, we simultaneously fill with this thimerosal of food 10mL, Continuous Observation 6 hours after rabbit is emotionally stable to two healthy adult rabbit.Before filling with food the palmic rate of rabbit be respectively 142 times/min, 141 times/min, blood pressure is 90/75mmHg; Fill with food latter 1 hour rabbit average palmic rate be respectively 137 times/min, 138 times/min, blood pressure is 110/80mmHg; Fill with food latter 6 hours rabbit average palmic rate be respectively 142 times/min, 141 times/min, blood pressure is respectively 91/77mmHg, 90/75mmHg; The PD of whole process observation rabbit and mucous membrane, no abnormal.Health health check-up is healthy and build is moderate volunteer has drunk this Chinese-herb disinfectant of 50mL, contrast drink before routine blood test report and drink the report of the rear empty stomach routine blood test of 2 hours, find that 3 indexs slightly fluctuate, but all the time in range of normal value.The electrocardio index, oxygen saturation, PD, tongue fur color, lip color etc. of whole process to volunteer have done the half an hour of observation once, do not find significant change.Experiment proves, the Chinese-herb disinfectant that the present invention relates to does not have toxic and side effect to Healthy People.
The Chinese-herb disinfectant that the present invention relates to also has carried out the test of skin toxicity.By thimerosal uniform application on the skin of back of a nude mice, smeared every 6 hours and once observe once simultaneously, the continuous exception of 4 all non-nude mice skins and the anomaly of nude mice activity.Thimerosal is spread upon place's skins such as the back of the hand of healthy volunteer, the palm of the hand, thigh, ancon, smeared every 6 hours and once observe once simultaneously, the continuous anomaly all not observing skin for 4 times, volunteer does not feel any discomfort.This thimerosal is spread upon on the shallow table wound of volunteer's finger tip, within every 12 hours, observe once, do not find the symptoms such as wound redness, suppuration, itch.Experiment proves, the Chinese-herb disinfectant that the present invention relates to has no side effect to human body skin, nonirritant.Use this thimerosal to clean veterinary antibiotics, tableware, can not hand be hindered.
Above content is in conjunction with embodiment and experimental result further explanation made for the present invention, can not think that the specific embodiment of the present invention is only limited to these explanations.Without departing from the inventive concept of the premise, simple change can also be made to medicament compatibility and compound method, all should be considered as scope.
Form take medicine before blood routine examination report
Form is taken medicine the report of latter 2 hours routine blood tests
Claims (9)
1. a Chinese-herb disinfectant, primary raw material used is prepared according to following weight ratio: Chinese honey locust 15-50 part, fresh purslane 15-30 part, wormwood 20-25 part, capsule of weeping forsythia 15-25 part, root of large-flowered skullcap 15-25 part, coptis 5-10 part, honeysuckle 15-30 part, wolf's milk 10-15 part, dandelion 10-30 part, oriental wormwood 15-30 part, pyrrosia lingua 15-20 part, mother chrysanthemum 20-30 part.
2. the primary raw material according to right 1, as a further improvement on the present invention, primary raw material used is prepared according to following weight ratio: Chinese honey locust 15 parts, fresh purslane 15 parts, wormwood 20 parts, the capsule of weeping forsythia 20 parts, the root of large-flowered skullcap 20 parts, the coptis 10 parts, honeysuckle 15 parts, wolf's milk 12 parts, dandelion 30 parts, oriental wormwood 15 parts, pyrrosia lingua 15 parts, mother chrysanthemum 30 parts.
3. according to right 2, primary raw material is ground into respectively last process of sieving, then by powder one Homogeneous phase mixing of all medicinal materials, put into ethanol water, isolated air pressurized, to several atmospheric pressure, is heated to liquid boiling, constantly stir simultaneously, keep press filtration after 3 hours to obtain liquid.
4. according to right 3, residue obtained for the press filtration 3-5 of adding times of ethanol water is proceeded pressurized liquid extraction, 2 times repeatedly, after liquid one Homogeneous phase mixing of three gained, put into sedimentation high speed centrifugation filter by the centrifugal elimination removal of impurity.
5. according to right 4, the liquid removing impurity through centrifugal elimination is removed the macromolecular substances such as protein, polysaccharide further by ultrafiltration, wherein milipore filter molecular cut off is 2000-10000.
6. according to right 5, the liquid through Treatment with Ultrafiltration is put into the container of band blast pipe, be heated to more than 78.4 degrees Celsius less than 85 degrees Celsius, heating evaporation ethanol, continue concentrated liquid and obtain concentrate.
7. the peppermint oil alcoholic solution adding 1-5mL according to 1L concentrate after concentrate described in right 6 being loaded brown bottle or opaque-plastic bottle adds peppermint oil alcoholic solution to concentrate and seals at once.
8., according to right 8, namely peppermint oil and alcohol are obtained peppermint oil alcoholic solution of the present invention according to uniform stirring after volume ratio 1:1 mixing.
9. enrichment facility end can recovered alcohol with condenser pipe.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410365816.4A CN105309496A (en) | 2014-07-29 | 2014-07-29 | Chinese herbal medicine disinfectant |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410365816.4A CN105309496A (en) | 2014-07-29 | 2014-07-29 | Chinese herbal medicine disinfectant |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105309496A true CN105309496A (en) | 2016-02-10 |
Family
ID=55238595
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201410365816.4A Pending CN105309496A (en) | 2014-07-29 | 2014-07-29 | Chinese herbal medicine disinfectant |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105309496A (en) |
Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106342951A (en) * | 2016-08-28 | 2017-01-25 | 广西兴胜农牧有限公司 | Disinfectant special for pigpen |
| CN106342963A (en) * | 2016-08-28 | 2017-01-25 | 广西兴胜农牧有限公司 | Hog house disinfectant |
| CN106342938A (en) * | 2016-08-28 | 2017-01-25 | 广西兴胜农牧有限公司 | Disinfectant for disinfecting pigpen |
| CN106342950A (en) * | 2016-08-28 | 2017-01-25 | 广西兴胜农牧有限公司 | Hog house disinfectant and preparation method thereof |
| CN106376611A (en) * | 2016-09-18 | 2017-02-08 | 肇庆市高新区创客科技有限公司 | Environment-friendly water treatment antibacterial agent and preparation method thereof |
| CN107189576A (en) * | 2017-07-13 | 2017-09-22 | 安庆市星空化工涂料有限责任公司 | A kind of glutinous rice coating |
| CN107821483A (en) * | 2017-11-27 | 2018-03-23 | 广西协成日用化工有限公司 | A kind of table-ware disinfection liquid |
| CN110742093A (en) * | 2019-11-12 | 2020-02-04 | 云南省农业科学院农业环境资源研究所 | Vegetable waste leaf sterilization treatment agent and preparation and application thereof |
| CN111248231A (en) * | 2020-03-31 | 2020-06-09 | 白山蜂收蜂制品科技开发有限公司 | Selenium-rich plant source disinfectant, and preparation method and application thereof |
| CN114176099A (en) * | 2021-12-15 | 2022-03-15 | 何连旺 | Preparation process of environment-friendly disinfectant |
| CN115152806A (en) * | 2022-08-26 | 2022-10-11 | 上海瑞帝安生物科技有限公司 | Chinese herbal medicine air disinfectant and preparation method thereof |
-
2014
- 2014-07-29 CN CN201410365816.4A patent/CN105309496A/en active Pending
Cited By (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106342951A (en) * | 2016-08-28 | 2017-01-25 | 广西兴胜农牧有限公司 | Disinfectant special for pigpen |
| CN106342963A (en) * | 2016-08-28 | 2017-01-25 | 广西兴胜农牧有限公司 | Hog house disinfectant |
| CN106342938A (en) * | 2016-08-28 | 2017-01-25 | 广西兴胜农牧有限公司 | Disinfectant for disinfecting pigpen |
| CN106342950A (en) * | 2016-08-28 | 2017-01-25 | 广西兴胜农牧有限公司 | Hog house disinfectant and preparation method thereof |
| CN106376611A (en) * | 2016-09-18 | 2017-02-08 | 肇庆市高新区创客科技有限公司 | Environment-friendly water treatment antibacterial agent and preparation method thereof |
| CN107189576A (en) * | 2017-07-13 | 2017-09-22 | 安庆市星空化工涂料有限责任公司 | A kind of glutinous rice coating |
| CN107821483A (en) * | 2017-11-27 | 2018-03-23 | 广西协成日用化工有限公司 | A kind of table-ware disinfection liquid |
| CN110742093A (en) * | 2019-11-12 | 2020-02-04 | 云南省农业科学院农业环境资源研究所 | Vegetable waste leaf sterilization treatment agent and preparation and application thereof |
| CN111248231A (en) * | 2020-03-31 | 2020-06-09 | 白山蜂收蜂制品科技开发有限公司 | Selenium-rich plant source disinfectant, and preparation method and application thereof |
| CN114176099A (en) * | 2021-12-15 | 2022-03-15 | 何连旺 | Preparation process of environment-friendly disinfectant |
| CN114176099B (en) * | 2021-12-15 | 2023-08-11 | 安徽绿阳生物科技有限公司 | Environment-friendly disinfectant preparation process |
| CN115152806A (en) * | 2022-08-26 | 2022-10-11 | 上海瑞帝安生物科技有限公司 | Chinese herbal medicine air disinfectant and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN105309496A (en) | Chinese herbal medicine disinfectant | |
| CN104255823B (en) | A kind of plant bacteriostatic composition and its application in liquid detergent | |
| US7329421B2 (en) | Process of manufacturing clear juice from the leaves of the Aloe vera plant | |
| CN101428047A (en) | Process for producing pericarpium granati total phenols and uses thereof | |
| CN104522835A (en) | Traditional Chinese medicinal herbal preservative, as well as preparation method and bacterium inhibition method thereof | |
| CN105748398A (en) | Oral care solution and preparation method thereof | |
| CN106390182A (en) | Sanitary napkin with antibacterial natural fiber surface layer and manufacturing method of sanitary napkin with antibacterial natural fiber surface layer | |
| CN106109815A (en) | The disinfection solution that a kind of clinical laboratory personnel wash one's hands | |
| CN103181597B (en) | Ledum palustre detoxication health care liquid and preparation method thereof | |
| US20220040249A1 (en) | Liquid invisible mask with broad-spectrum bacteriostasis and preparation method and using method thereof | |
| CN104367507A (en) | Skincare solution and preparation method thereof | |
| CN104095789A (en) | Special Chinese honey locust liquid soap used in clinical laboratory and preparation method thereof | |
| CN106342945A (en) | Disinfectant for toys | |
| CN110917077B (en) | Natural plant bath foam | |
| CN103815587A (en) | Mask capable of preventing inhalation of harmful tiny particulate matters in air effectively and inhibiting bacteria and production method of mask | |
| CN104436116B (en) | A kind of rosemary lavipeditum powder and preparation method thereof | |
| CN103798301B (en) | A kind of Chinese medicine compound prescription general flavone with antibacterial action and preparation method thereof | |
| CN107164096A (en) | A kind of extraction purification of Geophila herbacea (L) O Kumtze volatile oil and detection method and its application | |
| CN107950855A (en) | A kind of natural anticorrosion compound for food and preparation method thereof | |
| CN106421511A (en) | Aloe antibacterial composition and preparation method thereof | |
| CN105062684A (en) | Vetiver grass compound essential oil and preparation method thereof | |
| CN106398873A (en) | Preparation method of tea flower essential oil | |
| CN107751863A (en) | A kind of aloes lozenge and preparation method thereof | |
| CN110278967A (en) | A kind of antibacterial spray and preparation method | |
| CN104606629A (en) | Traditional Chinese medicine disinfection solution for clinical laboratory |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| WD01 | Invention patent application deemed withdrawn after publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20160210 |