CN105288722A - Waterproof ventilating liquid adhesive bandage and preparation method thereof - Google Patents
Waterproof ventilating liquid adhesive bandage and preparation method thereof Download PDFInfo
- Publication number
- CN105288722A CN105288722A CN201510776194.9A CN201510776194A CN105288722A CN 105288722 A CN105288722 A CN 105288722A CN 201510776194 A CN201510776194 A CN 201510776194A CN 105288722 A CN105288722 A CN 105288722A
- Authority
- CN
- China
- Prior art keywords
- parts
- waterproof
- adhesive bandage
- liquid adhesive
- polyvinylpyrrolidone
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Medicinal Preparation (AREA)
- Materials For Medical Uses (AREA)
Abstract
The invention belongs to the technical field of medical treatment and relates to a waterproof ventilating liquid adhesive bandage and a preparation method thereof. The waterproof ventilating liquid adhesive bandage comprises, by weight, 5-20 parts of nitrocellulose, 30-70 parts of acetone, 0.1-1 part of polyvinylpyrrolidone, 10-50 parts of ethanol, 4-15 parts of tributyl 2-acetylcitrate and 3-10 parts of ether. A wound part can be directly coated with the waterproof ventilating liquid adhesive bandage and after coating, a film is fast formed, tightly covers the wound surface, has waterproof and ventilating effects and is convenient for use. The waterproof ventilating liquid adhesive bandage can effectively promote wound heal, prevent infection and reduce pain.
Description
Technical field
The invention belongs to field of medical technology, liquid adhesive bandage being specifically related to a kind of waterproof and breathable and preparation method thereof.
Background technology
Common adhesive bandage all needs to use medical proof fabric to be affixed on human body wound site in the market, and adhesive plaster wrapping can cause the whiting of wrapping area skin, and even some people there will be skin allergy.Liquid adhesive bandage is a kind of novel adhesive bandage; because containing filmogen in formula; directly can be applied to wound surface; layer protecting film can be formed in short time; waterproof, isolated pollution, quick-acting haemostatic powder, sterilization, pain relieving, subside a swelling, alleviate edema cicatrization; promote wound healing, without the need to using adhesive plaster.
Summary of the invention
Technical problem to be solved by this invention is to provide a kind of liquid adhesive bandage of waterproof and breathable.
Technical problem to be solved by this invention is achieved by the following technical programs:
A liquid adhesive bandage for waterproof and breathable, comprises the component of following weight portion:
Nitrocellulose 5 ~ 20 parts;
30 ~ 70 parts, acetone;
Polyvinylpyrrolidone 0.1 ~ 1 part;
Ethanol 10 ~ 50 parts;
Tributyl 2-acetylcitrate 4 ~ 15 parts.
Further, the liquid adhesive bandage of described waterproof and breathable, can also contain ether component, each composition weight component is:
Nitrocellulose 5 ~ 18 parts;
35 ~ 65 parts, acetone;
Polyvinylpyrrolidone 0.2 ~ 0.9 part;
Ethanol 15 ~ 45 parts;
Tributyl 2-acetylcitrate 5 ~ 14 parts;
Ether 3 ~ 10 parts.
Further, at least one of described nitrocellulose raw material sources in hardwood fiber, cork fibrous, cotton fiber.
Further, described polyvinylpyrrolidone is selected from PVPK12, at least one in PVPK15, PVPK17, PVPK25, PVPK30, PVPK45, PVPK60, PVPK70, PVPK80, PVPK85, PVPK90, PVPK100, PVPK110, PVPK120, PVPK150.
Further, at least one in described polyvinylpyrrolidone preferred PVPK80, PVPK85, PVPK90, PVPK100, PVPK110, PVPK120, PVPK150.The polyvinylpyrrolidone that the present invention preferred K value is large, the larger viscosity of K value is higher, and the adhesive bandage caking property be configured to is stronger.The polyvinylpyrrolidone of different K values can be selected according to wound surface diverse location, reach different bond effects.
A preparation method for the liquid adhesive bandage of waterproof and breathable as above, is characterized in that, be made up of following steps:
(1) take the ethanol of formula ratio, acetone, tributyl 2-acetylcitrate be placed in container mix homogeneously;
(2) in said mixture, add the polyvinylpyrrolidone stirring and dissolving of formula ratio;
(3), after treating (2) step mixture mix homogeneously, add nitrocellulose stirring and make it fully dissolve;
(4) place, treat that bubble collapse obtains waterproof and breathable liquid adhesive bandage product.
Utilize the chemical property that acetone and ethanol are miscible mutually, water miscible polyvinylpyrrolidone and oil-soluble nitrocellulose well can be dissolved, disperse.Oil-soluble nitrocellulose plays well isolated waterproof action, and water miscible polyvinylpyrrolidone is embedded in nitrocellulose space structure, forms through hole and plays good permeation functions.The polyvinylpyrrolidone of different K values plays different cementations, can select the polyvinylpyrrolidone of different adhesive property according to wound site.Add a certain amount of ethanol and ether, have antibacterial, sterilization and analgesic effect.Add the pliability effect that tributyl 2-acetylcitrate plays reinforcing membrane, when being applied to wound site, film can be fastened on skin surface, is not easy to come off simultaneously.When the ethanol contained and acetone coat wound site, the sensation of absorbing heat and feeling nice and cool to people of volatilizing rapidly, reduces the pain of wound surface.
The present invention has following beneficial effect:
The liquid adhesive bandage of waterproof and breathable of the present invention, can directly be applied to skin trauma position, and restriction easy to use, not to be subject to wound present position, effectively prevents wound infection.The film forming matter nitrocellulose contained, polyvinylpyrrolidone are rapidly in wound surface place film forming, and a certain proportion of tributyl 2-acetylcitrate contributes to the softness improving film.The ethanol and the ether that add proper proportion can play antibacterial, sterilization rapidly simultaneously, alleviate the effect of wound pain sense.
Detailed description of the invention
Below in conjunction with embodiment, the present invention will be described in detail, and embodiment is only the preferred embodiment of the present invention, is not limitation of the invention.
Embodiment 1:
A liquid adhesive bandage preparation method for waterproof and breathable, comprises the steps:
(1) take the ethanol of 15 parts, the acetone of 45 parts, the tributyl 2-acetylcitrate of 8 parts be placed in container mix homogeneously;
(2) in said mixture, add polyvinylpyrrolidone (PVPK85) stirring and dissolving of 0.3 part;
(3), after treating (2) step mixture mix homogeneously, the nitrocellulose stirring adding 8 parts makes it fully dissolve;
(4) place, treat that bubble collapse obtains waterproof, ventilative liquid adhesive bandage product.
Embodiment 2:
A liquid bandage preparation method for waterproof and breathable, comprises the steps:
(1) take the ethanol of 50 parts, the acetone of 70 parts, the tributyl 2-acetylcitrate of 15 parts be placed in container mix homogeneously;
(2) in said mixture, 1 part is added, polyvinylpyrrolidone (PVPK90) stirring and dissolving;
(3), after treating (2) step mixture mix homogeneously, the nitrocellulose stirring adding 20 parts makes it fully dissolve;
(4) place, treat that bubble collapse obtains waterproof, ventilative liquid adhesive bandage product.
Embodiment 3:
A liquid adhesive bandage preparation method for waterproof and breathable, comprises the steps:
(1) take the ethanol of 35 parts, the acetone of 50 parts, 3 parts of ether, the tributyl 2-acetylcitrate of 10 parts be placed in container mix homogeneously;
(2) in said mixture, add polyvinylpyrrolidine (PVPK100) the ketone stirring and dissolving of 0.5 part;
(3), after treating (2) step mixture mix homogeneously, the nitrocellulose stirring adding 15 parts makes it fully dissolve;
(4) place, treat that bubble collapse obtains waterproof, ventilative liquid adhesive bandage product.
Embodiment 4:
A liquid adhesive bandage preparation method for waterproof and breathable, comprises the steps:
(1) take the ethanol of 45 parts, the acetone of 60 parts, 9 parts of ether, the tributyl 2-acetylcitrate of 14 parts be placed in container mix homogeneously;
(2) in said mixture, add polyvinylpyrrolidone (PVPK110) stirring and dissolving of 0.8 part;
(3), after treating (2) step mixture mix homogeneously, the nitrocellulose stirring adding 18 parts makes it fully dissolve;
(4) place, treat that bubble collapse obtains waterproof, ventilative liquid adhesive bandage product.
Embodiment 1 gained sample is coated the different wound site of experimenter to test, obtains following experimental result:
(1), under room temperature, normal body temperature gets final product film forming in 20 seconds, and film forming speed is fast;
(2) diaphragm is soaked in water and can keeps not breaking for 24 hours, and waterproof effect is excellent;
(3) position being coated with product of the present invention there will not be whiteness of skin situation in 3 ~ 5 days, and permeability is good;
(4) scald through actual measurement human body surface small size, abrade, hurt, stab can contact water arbitrarily after once smearing film forming, can not infect, 3-5 days wound normal healings.
From above experimental results, the liquid adhesive bandage of waterproof and breathable of the present invention can at wound site rapid film formation, and waterproof, permeability are excellent, the film soft comfortable of formation, reduces wound pain sense, accelerates the healing of wound surface.
Claims (6)
1. a liquid adhesive bandage for waterproof and breathable, is characterized in that, comprises the component of following weight portion:
Nitrocellulose 5 ~ 20 parts;
30 ~ 70 parts, acetone;
Polyvinylpyrrolidone 0.1 ~ 1 part;
Ethanol 10 ~ 50 parts;
Tributyl 2-acetylcitrate 4 ~ 15 parts.
2. the liquid adhesive bandage of waterproof and breathable according to claim 1, is characterized in that, can also contain ether component, each composition weight component is:
Nitrocellulose 5 ~ 18 parts;
35 ~ 65 parts, acetone;
Polyvinylpyrrolidone 0.2 ~ 0.9 part;
Ethanol 15 ~ 45 parts;
Tributyl 2-acetylcitrate 5 ~ 14 parts;
Ether 3 ~ 10 parts.
3. the liquid adhesive bandage of waterproof and breathable according to claim 1, is characterized in that, at least one of described nitrocellulose raw material sources in hardwood fiber, cork fibrous, cotton fiber.
4. the liquid adhesive bandage of waterproof and breathable according to claim 1, is characterized in that, described polyvinylpyrrolidone is selected from PVPK12, PVPK15, PVPK17, PVPK25, PVPK30, PVPK45, PVPK60, PVPK70, PVPK80, PVPK85, PVPK90, PVPK100, PVPK110, at least one in PVPK120, PVPK150.
5. the liquid adhesive bandage of waterproof and breathable according to claim 4, is characterized in that, at least one in described polyvinylpyrrolidone preferred PVPK80, PVPK85, PVPK90, PVPK100, PVPK110, PVPK120, PVPK150.
6. a preparation method for the liquid adhesive bandage of waterproof and breathable according to claim 1, is characterized in that, be made up of following steps:
(1) take the ethanol of formula ratio, acetone, tributyl 2-acetylcitrate be placed in container mix homogeneously;
(2) in said mixture, add the polyvinylpyrrolidone stirring and dissolving of formula ratio;
(3), after treating (2) step mixture mix homogeneously, add nitrocellulose stirring and make it fully dissolve;
(4) place, treat that bubble collapse obtains waterproof and breathable liquid adhesive bandage product.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510776194.9A CN105288722A (en) | 2015-11-13 | 2015-11-13 | Waterproof ventilating liquid adhesive bandage and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510776194.9A CN105288722A (en) | 2015-11-13 | 2015-11-13 | Waterproof ventilating liquid adhesive bandage and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN105288722A true CN105288722A (en) | 2016-02-03 |
Family
ID=55186985
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510776194.9A Pending CN105288722A (en) | 2015-11-13 | 2015-11-13 | Waterproof ventilating liquid adhesive bandage and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN105288722A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105999360A (en) * | 2016-07-22 | 2016-10-12 | 严锋 | Anti-bacterial liquid adhesive bandage and preparation method thereof |
| CN112546290A (en) * | 2020-12-17 | 2021-03-26 | 江苏耐雀生物工程技术有限公司 | Antibacterial and anti-inflammatory liquid adhesive bandage and preparation method thereof |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003047643A1 (en) * | 2001-12-06 | 2003-06-12 | Johnson & Johnson Medical Limited | Controlled release therapeutic wound dressings |
| CN1561966A (en) * | 2004-04-13 | 2005-01-12 | 李宇光 | Liquid wound plaster and its preparing method |
| CN101357108A (en) * | 2007-08-01 | 2009-02-04 | 冷博 | Skin surface quick film-forming agent |
| CN102058900A (en) * | 2010-12-13 | 2011-05-18 | 都本立 | Waterproof liquid bandage for wound surface protection and preparation method thereof |
| CN102274542A (en) * | 2011-08-30 | 2011-12-14 | 夏敬民 | Film-forming type waterproof breathable wound protecting liquid and preparation method thereof |
| CN104056299A (en) * | 2014-07-08 | 2014-09-24 | 烟台隽秀生物科技有限公司 | Liquid wound protecting membrane and preparation method thereof |
| CN104814982A (en) * | 2015-04-21 | 2015-08-05 | 华侨大学 | Traditional Chinese medicine liquid adhesive bandage and preparation method |
-
2015
- 2015-11-13 CN CN201510776194.9A patent/CN105288722A/en active Pending
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2003047643A1 (en) * | 2001-12-06 | 2003-06-12 | Johnson & Johnson Medical Limited | Controlled release therapeutic wound dressings |
| CN1561966A (en) * | 2004-04-13 | 2005-01-12 | 李宇光 | Liquid wound plaster and its preparing method |
| CN101357108A (en) * | 2007-08-01 | 2009-02-04 | 冷博 | Skin surface quick film-forming agent |
| CN102058900A (en) * | 2010-12-13 | 2011-05-18 | 都本立 | Waterproof liquid bandage for wound surface protection and preparation method thereof |
| CN102274542A (en) * | 2011-08-30 | 2011-12-14 | 夏敬民 | Film-forming type waterproof breathable wound protecting liquid and preparation method thereof |
| CN104056299A (en) * | 2014-07-08 | 2014-09-24 | 烟台隽秀生物科技有限公司 | Liquid wound protecting membrane and preparation method thereof |
| CN104814982A (en) * | 2015-04-21 | 2015-08-05 | 华侨大学 | Traditional Chinese medicine liquid adhesive bandage and preparation method |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105999360A (en) * | 2016-07-22 | 2016-10-12 | 严锋 | Anti-bacterial liquid adhesive bandage and preparation method thereof |
| CN112546290A (en) * | 2020-12-17 | 2021-03-26 | 江苏耐雀生物工程技术有限公司 | Antibacterial and anti-inflammatory liquid adhesive bandage and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103006923B (en) | Chinese medicinal liquid band-aid and preparation method | |
| CN102058900B (en) | Waterproof liquid bandage for wound surface protection and preparation method thereof | |
| CN104257639A (en) | Film coating agent for wound surface treatment and preparation method of film coating agent | |
| CN105363066B (en) | A kind of liquid adhesive bandage | |
| CN105288722A (en) | Waterproof ventilating liquid adhesive bandage and preparation method thereof | |
| CN104971377A (en) | Liquid wound glue and preparation method | |
| CN104056301A (en) | Traditional Chinese medicine-type hemostatic anti-inflammation liquid bandage and preparation method thereof | |
| CN106146960A (en) | A kind of preparation method of vapor-permeable type antibacterial sponge | |
| CN104056299A (en) | Liquid wound protecting membrane and preparation method thereof | |
| CN102579921A (en) | Foot-bathing traditional Chinese medicine powder and preparation method thereof | |
| CN102579193A (en) | Silk and aloe band-aid | |
| CN103211350A (en) | Insoles with beriberi treating function | |
| CN102895425B (en) | Bentonite-containing woundplaster | |
| KR101502083B1 (en) | A hygienic diaper include tea-tree, alum, zeolite and SAP a composition and that of manufacturing method | |
| CN108653377A (en) | A kind of mongolian medicine patch and preparation method for treating skin trauma | |
| KR20190034478A (en) | Hydrocotyle sibthorpioides LAMIM containing disposable band | |
| CN105664235A (en) | Gel adhesive bandage, preparation method and inventive principle | |
| CN105919365B (en) | A kind of ventilative cotton-wadded quilt for improving sleep quality | |
| Glat et al. | The use of Suprathel® in the treatment of pediatric burns: Retrospective review of first pilot trial in a burn unit in the United States | |
| CN107661537A (en) | A kind of liquid Wound surface protection film containing biological glass ceramic and chitosan | |
| CN103524819A (en) | Activated carbon latex | |
| KR20060066182A (en) | Paint of chinese medi-cine | |
| CN204814416U (en) | Woundplast that contains porous haydite | |
| CN204890353U (en) | Tea odor type woundplast | |
| CN105688251A (en) | Viscous type plaster bandage and method for preparing same |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20160203 |