CN105287975A - Traditional Chinese medicine composition for treating hyperlipidemia and preparations thereof - Google Patents

Traditional Chinese medicine composition for treating hyperlipidemia and preparations thereof Download PDF

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CN105287975A
CN105287975A CN201510915314.9A CN201510915314A CN105287975A CN 105287975 A CN105287975 A CN 105287975A CN 201510915314 A CN201510915314 A CN 201510915314A CN 105287975 A CN105287975 A CN 105287975A
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medicine composition
hyperlipidemia
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CN105287975B (en
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林天东
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Abstract

The invention discloses a traditional Chinese medicine composition for treating hyperlipidemia, which comprises the following raw materials in parts by weight: 200-400 parts of radix polygonum multiflorum preparata, 150-300 parts of herba taxilli, 200-400 parts of semen cassiae, 100-200 parts of herba artemisiae capillariae, 100-200 parts of fructus rosae laevigatae, 100-300 parts of herba leonuri, 150-300 parts of rhizoma alismatis, and 100-200 parts of fructus crataegi. The traditional Chinese medicine composition is used for treating hyperlipidemia and arterial atherosclerosis; and the traditional Chinese medicine composition is prepared by taking herba taxilli, herba leonuri and fructus crataegi which achieve the effects of nourishing liver and kidney, reducing blood fat, promoting digestion, eliminating dyspepsia, and promoting blood circulation to remove blood stasis as main herbal materials and taking rhizoma alismatis and herba artemisiae capillariae which eliminate dampness and heat and alleviate water retention, radix polygonum multiflorum preparata, semen cassiae and fructus rosae laevigatae which replenish kidney essence, remove heat from the liver, and loosen the bowel to relieve constipation as auxiliary herbal materials, so that an effect of alleviating hyperlipidemia is achieved.

Description

A kind of Chinese medicine composition and preparation thereof for the treatment of hyperlipidemia
Technical field
The present invention relates to technical field of Chinese medicine, particularly relate to a kind of Chinese medicine composition and preparation thereof for the treatment of hyperlipidemia.
Background technology
Hyperlipidemia is because blood lipid metabolism gets muddled, lipid metabolism or running are extremely, make the paranormal disease of lipid level in blood plasma, for common clinical, frequently-occurring disease, again the key factor causing cardiovascular and cerebrovascular disease, with giddy, dizziness, headache, feeling of oppression and pain in the chest, abdominal distention, fat equipotential principal character.Hyperlipemia can be divided into constitutional and Secondary cases two class.Constitutional is relevant with heredity with congenital, due to single-gene defect or polygenes defect, make the receptor of the transhipment of participation lipoprotein and metabolism, enzyme or apolipoprotein caused by abnormal, or cause due to environmental factors (diet, nutrition, medicine) with by unknown mechanism.Secondary cases is multiple is born in metabolic disorder disease (diabetes, hypertension, myxedema, hypothyroidism, obesity, hepatorenal disease, adrenal cortex function are hyperfunction), or with other factor age, sex, season, drink, smoking, diet, physical exertion, psychentonia, emotional activity etc. be relevant.Treat hyperlipidemia Chinese patent medicine in the market various, but price partially your uncertain therapeutic efficacy cut, therefore need invigorating the liver and kidney, blood fat reducing, promoting digestion and removing stagnation, blood circulation promoting and blood stasis dispelling is main.
Summary of the invention
In view of this, the invention provides a kind of Chinese medicine composition for the treatment of hyperlipidemia, achieve the effect reducing blood cholesterol levels and triglyceride, promoting digestion and removing stagnation, blood circulation promoting and blood stasis dispelling, high density lipoprotein increasing.
The technological means that the present invention adopts is as follows: a kind of Chinese medicine composition for the treatment of hyperlipidemia, comprises the raw material of following parts by weight:
Radix Polygoni Multiflori Preparata 200 ~ 400 parts, Herba Taxilli 150 ~ 300 parts, Semen Cassiae 200 ~ 400 parts, Herba Artemisiae Scopariae 100 ~ 200 parts, Fructus Rosae Laevigatae 100 ~ 200 parts, Herba Leonuri 100 ~ 300 parts, Rhizoma Alismatis 150 ~ 300 parts, Fructus Crataegi 100 ~ 200 parts.
Preferably, the raw material of following parts by weight is comprised:
Radix Polygoni Multiflori Preparata 250 ~ 350 parts, Herba Taxilli 200 ~ 250 parts, Semen Cassiae 250 ~ 350 parts, Herba Artemisiae Scopariae 120 ~ 150 parts, Fructus Rosae Laevigatae 120 ~ 150 parts, Herba Leonuri 200 ~ 250 parts, Rhizoma Alismatis 200 ~ 250 parts, Fructus Crataegi 120 ~ 150 parts.
Preferably, the raw material of following parts by weight is comprised:
Radix Polygoni Multiflori Preparata 300 parts, Herba Taxilli 225 parts, Semen Cassiae 300 parts, Herba Artemisiae Scopariae 150 parts, Fructus Rosae Laevigatae 150 parts, Herba Leonuri 225 parts, Rhizoma Alismatis 225 parts, Fructus Crataegi 150 parts.
Preferably, the raw material of following parts by weight is also comprised: Radix Astragali Preparata 300 ~ 400 parts.
Present invention also offers and adopt above-described a kind of preparation for the treatment of the Chinese medicine composition of hyperlipidemia, described preparation is the one of granule, oral liquid, pill, capsule, beverage.
Adopt a kind of Chinese medicine composition for the treatment of hyperlipidemia provided by the present invention, Herba Taxilli of the present invention, Herba Leonuri, Fructus Crataegi are principal agent, and mainly with invigorating the liver and kidney, blood fat reducing, promoting digestion and removing stagnation, blood circulation promoting and blood stasis dispelling is main, is aided with Rhizoma Alismatis, Herba Artemisiae Scopariae eliminating damp-heat, diuretic.Radix Polygoni Multiflori Preparata, Semen Cassiae, Fructus Rosae Laevigatae the kidney invigorating essence, liver heat removing, loosening bowel to relieve constipation, thus reach the effect reducing blood cholesterol levels, triglyceride, be usually used in hyperlipidemia and atherosclerosis, determined curative effect, effect is stable lasting.
Detailed description of the invention
With reference to " science of identification of Chinese materia medica ", " Chinese Pharmacopoeia ", " Chinese medicine voluminous dictionary " books.
Radix Polygoni Multiflori Preparata
Source: be the dried root of polygonum multiflorum thunb.
Decoction pieces character: this product is sheet, table rice and flour rufous or crineous, matter is hard, unilateral visible irregular muscle arteries and veins point, complete plane of structure, central authorities are a larger core, outside skin zone hash Nanjing brocade shape decorative pattern, section cutin sample, sepia or black, and taste is slightly bitter sweet, puckery, invigorating the liver and kidney, benefiting essence-blood, relieving constipation.
Application: empty for Liver and kidney two, the disease caused by asthenia of essence and blood, the modern times again for hypercholesterolemia, hypertension, coronary heart disease.
Herba Taxilli
Source: be the dry branch and leaf of Loranthaceae plant Herba Taxilli.
Decoction pieces character: stem branch is cylindrical, shape of cutting into chunks, the brown or bronzing of surface ash, leaf oblong, surperficial yellowish-brown, the blunt circle of tip, basal circular or wide wedge shape, Quan Yuan, keratin, puckery more.
Application: for rheumatic arthralgia, the diseases such as frequent fetal movement, modern for hypertension, coronary heart disease.
Semen Cassiae
Source: be the dry herb of leguminous plant Herba Leonuri.
Decoction pieces character: this product omits or short cylindrical shape square in Pedicellus et Pericarpium Trapae shape, two ends parallel oblique, likeness in form Horse hoof, surperficial yellow green, smoothly glossy, one end is smooth, and one end is tiltedly sharp, and matter is hard, not easily broken, mildly bitter flavor.Heat clearing away stomach invigorating, blood circulation promoting and blood stasis dispelling
Application: sting puckery pain for liver-heat or wind heat order, or constipation with heat retention, modern for hypertension.
Herba Artemisiae Scopariae
Source: be the dry seedling of feverfew Herba Artemisiae Scopariae or Artemisia scoparia Waldst. et Kit..
Decoction pieces character: this product is curling in agglomerate, celadon is soft as floss by canescence fine hair, and feeble QI is fragrant, mildly bitter flavor, clearing away heat-damp and promoting diuresis, promoting the function of the gallbladder to alleviate jaundice.
Application: for jaundice caused by damp-heat.
Fructus Rosae Laevigatae
Source: be the drying and ripening pseudocarp of rosaceous plant Fructus Rosae Laevigatae or the ripe holder of removing achene.
Decoction pieces character: this flat many middle rip cutting, half obovate, appearance reddish yellow or brownish red, there is protruding thorn-like point on surface, and there is the residual stem of plate-like calyx on top, and matter is hard.Inwall is light red yellow, and have the yellow achene of more grain, be wrapped with flaxen fine hair, sweet in the mouth acid is micro-puckery.
Application: for instability of kidney QI, seminal emission nebulousurine or frequent micturition, the enuresis etc.
Herba Leonuri
Source: be the dry herb of labiate Herba Leonuri.
Decoction pieces character: this product section of being shape, stem is square, the marrow of section adularescent, and leaf comes off or shrinkage more, and complete person's inferior leads palmate 3 is split, upper leaf pinniform drastic crack or be shallowly cleaved into 3, and wheel umbrella inflorescence axil is raw, bract thorn-like, and corolla is normal, and oneself falls de-, calyx tubular.Bitter in the mouth.
Application: for blood stasis amenorrhea, dysmenorrhea and traumatic injury blood stasis are had a pain, also for kiney edema, dysuria.
Rhizoma Alismatis
Source: for Rhizoma Alismatis can the dry tuber of plant.
Decoction pieces character: this product is sheet, outer surface yellow-white or fallow, unilateral HUANGBAI(sic) colour band graininess, and see brown muscle arteries and veins scattered in length and breadth, mildly bitter flavor.
Application: for retention of water-damp, edema, dysuria, again for deficiency of kidney yin, the disease of high Sheng of suffering from a deficiency of the kidney.
Radix Astragali Preparata
Source: be the Preparation process product of the Radix Astragali.
Decoction pieces character: exocuticle light brown or sepia, slightly gloss, visible vertical wrinkle or longitudinal furrow, tangent plane skin zone is light yellow, and xylem is yellow, has radial texture and crack, and some centers are even dry and decayed shape, pitchy or in cavity.Tool honey fragrance, taste is sweet, slightly stickiness, and that chews micro-ly has beany flavor.
Application: be applicable to spontaneous perspiration, night sweat, arthralgia due to stagnation of blood, edema, minimizing thrombosis, reduce blood pressure, carbuncle do not burst or burst and the disease such as not hold back for a long time.
Fructus Crataegi
Source: be the fruit of the drying of rosaceous plant Fructus Crataegi Fructus Pyri Pashiae and Crataegi cuneatae.First two is practised and is claimed " Fructus Crataegi ", and rear one is practised and claimed " Fructus Crataegi cuneatae ".
Fructus Crataegi decoction pieces character: be circular transverse section, the shrinkage of multireel limit is uneven, and crust redness has linen point, and sarcocarp buff is to light brown, and there are 2 ~ 5 lurid pits in cross section, feeble QI delicate fragrance, and taste is micro-sour-sweet.
Application: for the carnivorous long-pending infantile dyspepsia of oil, the modern times are used for hypertension.
Be described principle of the present invention and feature below, illustrated embodiment, only for explaining the present invention, is not intended to limit scope of the present invention.
Embodiment 1
Treat a Chinese medicine composition for hyperlipidemia, comprise following weight crude drug (unit: g):
Radix Polygoni Multiflori Preparata 300, Herba Taxilli 225, Semen Cassiae 300, Herba Artemisiae Scopariae 150, Fructus Rosae Laevigatae 150, Herba Leonuri 225, Rhizoma Alismatis 225, Fructus Crataegi 150.
Its preparation is pill, and the preparation method of pill comprises the steps:
1) each raw material is processed into decoction pieces through concocting.
2) take Radix Polygoni Multiflori Preparata, Semen Cassiae, Fructus Rosae Laevigatae, Rhizoma Alismatis, uctus Crataegi be placed in drying baker, baking temperature is 70 DEG C, and crushed after being dried is crossed 80 mesh sieves and obtained coarse powder.
3) be placed in jacketed pan by the raw material of remainder, add water and exceed powder 15cm decoction twice, each decocting time is 1.5h, merges twice medicinal liquid, is 1.1 clear paste by concentration of liquid medicine to proportion, and thickening temperature is 62 DEG C.
4) by step 2) obtained coarse powder and step 3) obtained clear paste is mixed into mixture, and mixture is placed in drying baker, and baking temperature is 70 DEG C, is crushed to the fine powder of 100 mesh sieves.
5) by step 4) obtained fine powder distillation water pill, making diameter is put into drying baker drying after the ball of 4.5mm, and baking temperature is 70 DEG C.
6) by step 5) in dry after obtained ball carry out polishing, the pill of the Chinese medicine composition of obtained treatment hyperlipidemia.
Embodiment 2
Treat a Chinese medicine composition for hyperlipidemia, comprise following weight raw material (unit: g):
Radix Polygoni Multiflori Preparata 200, Herba Taxilli 150, Semen Cassiae 200, Herba Artemisiae Scopariae 100, Fructus Rosae Laevigatae 100, Herba Leonuri 100, Rhizoma Alismatis 150, Fructus Crataegi 100, Radix Astragali Preparata 350.
Its preparation is pill, and the preparation method of pill comprises the steps:
1) each raw material is processed into decoction pieces through concocting.
2) take Radix Polygoni Multiflori Preparata, Semen Cassiae, Fructus Rosae Laevigatae, Rhizoma Alismatis, uctus Crataegi be placed in drying baker, baking temperature is 70 DEG C, and crushed after being dried is crossed 80 mesh sieves and obtained coarse powder.
3) be placed in jacketed pan by the raw material of remainder, add water and exceed powder 20cm decoction twice, each decocting time is 1.5h, merges twice medicinal liquid, is 1.25 clear paste by concentration of liquid medicine to proportion, and thickening temperature is 62 DEG C.
4) by step 2) obtained coarse powder and step 3) obtained clear paste is mixed into mixture, and mixture is placed in drying baker, and baking temperature is 70 DEG C, is crushed to the fine powder of 100 mesh sieves.
5) by step 4) obtained fine powder distillation water pill, making diameter is put into drying baker drying after the ball of 4.5mm, and baking temperature is 70 DEG C.
6) by step 5) in dry after obtained ball carry out polishing, the pill of the Chinese medicine composition of obtained treatment hyperlipidemia.
Embodiment 3
Treat a Chinese medicine composition for hyperlipidemia, comprise following weight raw material (unit: g):
Radix Polygoni Multiflori Preparata 400, Herba Taxilli 300, Semen Cassiae 400, Herba Artemisiae Scopariae 200, Fructus Rosae Laevigatae 200, Herba Leonuri 300, Rhizoma Alismatis 300, Fructus Crataegi 200.
Above-mentioned raw materials medicine makes granular preparation according to a conventional method.
Embodiment 4
Treat a Chinese medicine composition for hyperlipidemia, comprise following weight raw material (unit: g):
Radix Polygoni Multiflori Preparata 300, Herba Taxilli 200, Semen Cassiae 350, Herba Artemisiae Scopariae 150, Fructus Rosae Laevigatae 150, Herba Leonuri 200, Rhizoma Alismatis 250, Fructus Crataegi 150.
Above-mentioned raw materials medicine makes oral liquid formulations according to a conventional method.
Embodiment 5
Treat a Chinese medicine composition for hyperlipidemia, comprise following weight raw material (unit: g):
Radix Polygoni Multiflori Preparata 250, Herba Taxilli 250, Semen Cassiae 350, Herba Artemisiae Scopariae 150, Fructus Rosae Laevigatae 150, Herba Leonuri 250, Rhizoma Alismatis 250, Fructus Crataegi 150.
Above-mentioned raw materials medicine makes capsule formulation according to a conventional method.
Embodiment 6
Treat a Chinese medicine composition for hyperlipidemia, comprise following weight raw material (unit: g):
Radix Polygoni Multiflori Preparata 200, Herba Taxilli 200, Semen Cassiae 300, Herba Artemisiae Scopariae 150, Fructus Rosae Laevigatae 200, Herba Leonuri 100, Rhizoma Alismatis 150, Fructus Crataegi 200, Radix Astragali Preparata 400.
Above-mentioned raw materials medicine makes beverage preparation according to a conventional method.
Embodiment 7
Treat a Chinese medicine composition for hyperlipidemia, comprise following weight raw material (unit: g):
Radix Polygoni Multiflori Preparata 20, Herba Taxilli 15, Semen Cassiae 20, Herba Artemisiae Scopariae 10, Fructus Rosae Laevigatae 10, Herba Leonuri 10, Rhizoma Alismatis 15, Fructus Crataegi 10, Radix Astragali Preparata 30.
Above-mentioned raw materials medicine soak by water according to a conventional method.
Embodiment 8
Treat a Chinese medicine composition for hyperlipidemia, comprise following weight raw material (unit: g):
Radix Polygoni Multiflori Preparata 20, Herba Taxilli 15, Semen Cassiae 20, Herba Artemisiae Scopariae 10, Fructus Rosae Laevigatae 10, Herba Leonuri 10, Rhizoma Alismatis 15, Fructus Crataegi 10.
Above-mentioned raw materials medicine soak by water according to a conventional method.
Embodiment 9
Radix Polygoni Multiflori Preparata 20, Herba Taxilli 15, Semen Cassiae 20, Herba Artemisiae Scopariae 10, Fructus Rosae Laevigatae 10, Herba Leonuri 10, Rhizoma Alismatis 15, Fructus Crataegi 10, Radix Astragali Preparata 30.
Its preparation is pill, and the preparation method of pill comprises the steps:
1) each raw material is processed into decoction pieces through concocting.
2) take Radix Polygoni Multiflori Preparata, Semen Cassiae, Fructus Rosae Laevigatae, Rhizoma Alismatis, uctus Crataegi be placed in drying baker, baking temperature is 70 DEG C, and crushed after being dried is crossed 80 mesh sieves and obtained coarse powder.
3) be placed in jacketed pan by the raw material of remainder, add water and exceed powder 15cm decoction twice, each decocting time is 1.5h, merges twice medicinal liquid, is 1.1 clear paste by concentration of liquid medicine to proportion, and thickening temperature is 62 DEG C.
4) by step 2) obtained coarse powder and step 3) obtained clear paste is mixed into mixture, and mixture is placed in drying baker, and baking temperature is 70 DEG C, is crushed to the fine powder of 100 mesh sieves.
5) by step 4) obtained fine powder distillation water pill, making diameter is put into drying baker drying after the ball of 4.5mm, and baking temperature is 70 DEG C.
6) by step 5) in dry after obtained ball carry out polishing, the pill of the Chinese medicine composition of obtained treatment hyperlipidemia.
In order to verify beneficial effect of the present invention, a kind for the treatment of group 1 (embodiment 8), treatment group 2 (embodiment 9) for the treatment of the Chinese medicine composition of hyperlipidemia of the present invention carries out clinical trial with matched group (lescol see fluvastatin (fluvastatin) capsule) respectively, experimental technique and result as follows:
1, experimental technique
1.1, case selection: the patient 600 examples being met hyperlipidemia standard is divided into each 200 examples for the treatment of group 1 (Chinese patent medicine), treatment group 2 (Chinese patent medicine) and matched group (Western medicine) at random.Wherein man 272 example, female 328 example, the oldest person is 80 years old, and reckling is 25 years old, is at most, accounts for 72% with 40 ~ 60 years old person.Occupation: cadre 393 example, workman 114 example, peasant 93 example.The most elder of case is 15 years, and the shortest person is half a year, average 6.5 years.Wherein hypercholesterolemia 168 example, hypertriglyceridemia 294 example, combined hyperlipidemia familial 138 example, between group, severity extent compares without significant difference (P>0.05)
1.2, diagnostic criteria: cholesterol (CT) >5.5mmol/L, triglyceride (TC) >1.69mmol/L, high density lipoprotein (HDL) < 1.03mmol/L, low density lipoprotein, LDL (DC) >3.1mmol/L, above case all meets the diagnostic criteria of national higher medical institution teaching material (the 5th edition) hyperlipemia.
1.3, Therapeutic Method and the course for the treatment of:
Treatment group 1: a kind of Chinese medicine composition (embodiment 9) for the treatment of hyperlipidemia of the present invention, is developed into piller 60g by material medicine through Preparation Room in Hospital, subpackage 30g/ bottle, every day twice, each 9g.
Treatment group 2: a kind of Chinese medicine composition (embodiment 8) for the treatment of hyperlipidemia of the present invention, every day 1 dose, decocting is decoction being taken warmly use at twice, sooner or later respectively once.
Matched group: lescol see fluvastatin (fluvastatin) capsule, every day 1 time, each 20mg, takes during dinner or before sleeping.
Wherein treatment group 1, treatment group 2 and matched group are January is 1 course for the treatment of, is generally 2-3 the course for the treatment of, monthly checks blood fat 1 time, statistical result after 3 months.Treatments period all enjoins patient's rational diet, and appropriate exercise is discontinued the habit of smoking and drinking.
2, result
Treatment group 1: 56 examples of fully recovering (28%), effective 72 examples (36%), effective 62 examples (31%), invalid 10 examples (5%), always effective 190 examples (95%).
Treatment group 2: 58 examples of fully recovering (29%), effective 74 examples (37%), effective 60 examples (30%), invalid 8 examples (4%), always effective 192 examples (96%).
Matched group: 52 examples of fully recovering (26%), effective 62 examples (31%), effective 68 examples (34%), invalid 18 examples (9%), always effective 182 examples (91%).
The case number of cases of results of comparison is as shown in table 1 below:
Recovery from illness (example) Effective (example) Effectively (example) Invalid (example) Total effective (example)
Treatment group 1 56 72 62 10 190
Treatment group 2 58 74 60 8 192
Matched group 52 62 68 18 182
The case percent of results of comparison is as shown in table 2 below:
Recovery from illness (%) Effective (%) Effectively (%) Invalid (%) Total effective (%)
Treatment group 1 28 36 31 5 95
Treatment group 2 29 37 30 4 96
Matched group 26 31 34 9 91
Before wherein treating through between statistical procedures no significant difference (P>0.05) two groups, severity extent difference is without clear meaning, equalizing components is relatively good, has comparability before treatment, recovery from illness: transference cure, lipid examination recovers normal, and check is not being increased for 3 times.Effective: transference cure, lipid examination recovers normal, and check can raise once again.Effective: symptom obviously alleviates, lipid examination recovered normally within 2 months, and check Chang Zaidu raises.Invalid: symptom is without obviously alleviating, and lipid examination does not recover normal yet within March.
Table 1 analysis result show treatment group 1 always effective 190 examples be greater than matched group always effective 182 example; Treatment group 2 always effective 192 examples is greater than matched group always effective 182 examples.Table 2 analysis result shows that total effectively percent for the treatment of group 1 be the 95% total effectively percent being greater than matched group is 91%; Total effectively percent for the treatment of group 2 is the 96% total effectively percent being greater than matched group is 91%.Show that the curative effect for the treatment of group is better than matched group, namely a kind of effect for the treatment of the Chinese medicine composition of hyperlipidemia of the present invention is better than the effect of lescol see fluvastatin (fluvastatin) capsule.
3, analyze
The pathogenesis of hyperlipidemia is many by addicted to food greasy and surfeit flavour, impairing the spleen and stomach, or prolongedly bends over the desk, impairment caused by overstrain heart spleen, or sitting lying on bed for a long time, tired spleen of feeling frustrated, all can make dysfunction of the spleen in transportation, water paddy can not turn to precise and tiny, clear QI being mixed up with turbid QI, gather and wet into expectorant, hematogenous blockage, phlegm and blood stasis, hinder in venation, the splenopathy injures kidney for a long time, can cause deficiency of kidney-essence, sends out as primary disease.Therefore main QI invigorating, reduce phlegm and rush down turbid, blood circulation promoting and blood stasis dispelling, controlling nocturnal emission with astringent drugs.Hawthorn digesting eliminate indigestion in material medicine of the present invention, blood circulation promoting and blood stasis dispelling; Rhizoma Alismatis, Herba Artemisiae Scopariae eliminating damp-heat, to reduce phlegm; Radix Polygoni Multiflori Preparata, Semen Cassiae the kidney invigorating liver heat removing, loosening bowel to relieve constipation, lets out turbid; Herba Taxilli, Fructus Rosae Laevigatae tonifying the kidney to consolidate the essence, bone and muscle strengthening.There is the effect of good effect for reducing fat and wicking height lipoprotein, can the generation of prevention and corntrol cardiovascular and cerebrovascular disease effectively, development.And Western medicine Statins (fluvastatin) is though there is good effect for reducing fat, worry certain untoward reaction, as dyspepsia, insomnia, transaminase's rising, accidental myopathy etc.The compound antihyperglycemic ball that the present invention makes seldom finds untoward reaction in Clinical practice process, and relapse rate is few, is worth of widely use.
In sum, adopt a kind of Chinese medicine composition for the treatment of hyperlipidemia provided by the present invention, in raw material of the present invention, Herba Taxilli, Herba Leonuri, Fructus Crataegi are principal agent, main with invigorating the liver and kidney, blood fat reducing, promoting digestion and removing stagnation, blood circulation promoting and blood stasis dispelling is main, is aided with Rhizoma Alismatis, Herba Artemisiae Scopariae eliminating damp-heat, diuretic.Radix Polygoni Multiflori Preparata, Semen Cassiae, Fructus Rosae Laevigatae the kidney invigorating essence, liver heat removing, loosening bowel to relieve constipation, thus reach the effect of reduction hyperlipidemia, determined curative effect, effect is stable lasting, is that other Chinese patent medicine can not be compared.
The foregoing is only preferred embodiment of the present invention, not in order to limit the present invention, within the spirit and principles in the present invention all, any amendment made, equivalent replacement, improvement etc., all should be included within the scope of protection of the invention.

Claims (5)

1. treat the Chinese medicine composition of hyperlipidemia for one kind, it is characterized in that, comprise the raw material of following parts by weight: Radix Polygoni Multiflori Preparata 200 ~ 400 parts, Herba Taxilli 150 ~ 300 parts, Semen Cassiae 200 ~ 400 parts, Herba Artemisiae Scopariae 100 ~ 200 parts, Fructus Rosae Laevigatae 100 ~ 200 parts, Herba Leonuri 100 ~ 300 parts, Rhizoma Alismatis 150 ~ 300 parts, Fructus Crataegi 100 ~ 200 parts.
2. a kind of Chinese medicine composition for the treatment of hyperlipidemia as claimed in claim 1, it is characterized in that, comprise the raw material of following parts by weight: Radix Polygoni Multiflori Preparata 250 ~ 350 parts, Herba Taxilli 200 ~ 250 parts, Semen Cassiae 250 ~ 350 parts, Herba Artemisiae Scopariae 120 ~ 150 parts, Fructus Rosae Laevigatae 120 ~ 150 parts, Herba Leonuri 200 ~ 250 parts, Rhizoma Alismatis 200 ~ 250 parts, Fructus Crataegi 120 ~ 150 parts.
3. a kind of Chinese medicine composition for the treatment of hyperlipidemia as claimed in claim 2, is characterized in that, comprise the raw material of following parts by weight: Radix Polygoni Multiflori Preparata 300 parts, Herba Taxilli 225 parts, Semen Cassiae 300 parts, Herba Artemisiae Scopariae 150 parts, Fructus Rosae Laevigatae 150 parts, Herba Leonuri 225 parts, Rhizoma Alismatis 225 parts, Fructus Crataegi 150 parts.
4. a kind of Chinese medicine composition for the treatment of hyperlipidemia as claimed in claim 1, is characterized in that, also comprise the raw material of following parts by weight: Radix Astragali Preparata 300 ~ 400 parts.
5. a kind of preparation for the treatment of the Chinese medicine composition of hyperlipidemia as described in any one of Claims 1 to 4, is characterized in that, described preparation is the one of granule, oral liquid, pill, capsule, beverage.
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