CN105267891A - Traditional Chinese medicine composition for treating skin diseases - Google Patents
Traditional Chinese medicine composition for treating skin diseases Download PDFInfo
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- CN105267891A CN105267891A CN201510866586.4A CN201510866586A CN105267891A CN 105267891 A CN105267891 A CN 105267891A CN 201510866586 A CN201510866586 A CN 201510866586A CN 105267891 A CN105267891 A CN 105267891A
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Abstract
The invention relates to a traditional Chinese medicine composition for treating skin diseases. The composition is prepared from oyster, turtle shell, stir-baked squama manitis, dragon blood, herba artemisiae scopariae, felwort, cape jasmine, scutellaria baicalensis, lalang grass rhizome, semen plantaginis, rhizoma alismatis, radix bupleuri, salviae miltiorrhizae, dried radix rehmanniae, rhizoma atractylodis macrocephalae, poria cocos, rheum officinale, raw hawthorn, pawpaw, radix rehmanniae preparata, rhizoma sparganii, curcuma zedoary, ligustrum lucidum ait, angelica sinensis, radix paeoniae rubra, radix paeoniae alba, ligusticum wallichii, peach kernels, safflower carthamus, pericarpium citri reticulatae viride, pseudo-ginseng, earthworm, pericarpium citri reticulatae, radix curcumae, fructus lycii, fructus aurantii, rhizoma cyperi, rice sprout, malt, codonopsis pilosula, astragalus membranaceus and licorice root. The composition can be used for treating heat entering construction-blood and toxic heat flourishing, has the effects of clearing heat, cooling blood and relieving dizziness and itching, and is mainly used for treating erythroderma desquamativum, skin-loss type diseases, psoriasis, argyraemia and psoriasis.
Description
Technical field
The present invention relates to field of medicaments, relate in particular to one and treat dermopathic Chinese medicine composition.
Background technology
Skin is the outermost protective tissue of human body, is also the maximum organ of human body, mainly carries protection health, perspire, feels cold and hot and the function of pressure.Skin covers whole body, is easily subject to various invasion and attack, the situations such as such as fungal infection, wound, allergy, poisoning, viral infection.The multiplex antibacterial-anti-inflammatory drug of this type of dermatosis of Current treatments, have aerosol (YUNNAN BAIYAO), unguentum (dexamethasone acetate) etc., these medicines are used widely as nonprescription drugs.But these Drug therapy windows are narrow, it is better that such as YUNNAN BAIYAO is used for traumatism treatment effect, and it is mainly containing medical material that is antibacterial and blood circulation promoting and blood stasis dispelling, and can promote topical blood flow, have additional nutrients provisioning, promotes wound healing.Fungus, courses of infection, mosquito bite are not then acted on.And common skin medication dexamethasone acetate has antiinflammatory, antiallergic, Antishock function.But as adrenocortical hormone medicine, itself have multiple side effect, as immunosuppressant, resistance declines, easy infection, and tissue metabolism is vigorous, and wound is not easy to grow; Abnormal carbohydrate metabolism, occurs or diabetes is increased the weight of; Adrenal cortex function suppresses; Peptic ulcer; Seborrheic dermatitis etc.Modern medicine study shows, mostly dermatosis is microbial owing to causing a disease.Therefore pathogenic bacterium are suppressed to have great importance for treatment dermatosis.
Summary of the invention
The object of this invention is to provide one and treat dermopathic Chinese medicine composition.
In order to realize object of the present invention, the invention provides one and treat dermopathic Chinese medicine composition, it comprises the material of following weight portion: Concha Ostreae 30 parts, Carapax Trionycis 20 parts, stir-baked SQUAMA MANITIS 15 parts, Sanguis Draxonis 3 parts, Herba Artemisiae Scopariae 30 parts, Radix Gentianae 10 parts, Fructus Gardeniae 15 parts, Radix Scutellariae 15 parts, Rhizoma Imperatae 30 parts, Semen Plantaginis 30 parts, Rhizoma Alismatis 12 parts, Radix Bupleuri 10 parts, Radix Salviae Miltiorrhizae 30 parts, 20 parts, the Radix Rehmanniae, the Rhizoma Atractylodis Macrocephalae 15 parts, 20 parts, Poria, Radix Et Rhizoma Rhei 6 parts, Fructus Crataegi 15 parts, Fructus Chaenomelis 15 parts, 9 parts, Radix Rehmanniae Preparata, Rhizoma Sparganii 15 parts, Rhizoma Curcumae 15 parts, Fructus Ligustri Lucidi 30 parts, Radix Angelicae Sinensis 15 parts, Radix Paeoniae Rubra 15 parts, the Radix Paeoniae Alba 30 parts, Rhizoma Chuanxiong 15 parts, 10 parts, Semen Persicae, 10 parts, Flos Carthami, 10 parts, Pericarpium Citri Reticulatae Viride, Radix Notoginseng 6 parts, Pheretima 12 parts, Pericarpium Citri Reticulatae 10 parts, Radix Curcumae 15 parts, Fructus Lycii 15 parts, Fructus Aurantii 10 parts, Rhizoma Cyperi 10 parts, Fructus Setariae Germinatus 15 parts, 15 parts, Fructus Hordei Germinatus, Radix Codonopsis 30 parts, the Radix Astragali 30 parts and 10 parts, Radix Glycyrrhizae.
Preferably, the dermopathic Chinese medicine composition for the treatment of of the present invention also comprises the material of following weight portion: 7-(the fluoro-benzyloxy of 4-)-4,5-dihydro-2H-[1,2, the 4]-triazole [4,3-a] of 0.1 part quinoline-1-ketone.
More preferably, described Chinese medicine composition can be tablet, dispersible tablet, capsule, pill or decoction.
The present invention also provides 7-(the fluoro-benzyloxy of 4-)-4,5-dihydro-2H-[1,2,4]-triazole [4,3-a] and the purposes of quinoline-1-ketone in the dermopathic medicine of preparation treatment.
The present invention also provides 7-(the fluoro-benzyloxy of 4-)-4,5-dihydro-2H-[1,2,4]-triazole [4,3-a] and the purposes of quinoline-1-ketone in the medicine of preparation vitro inhibition Rhodobacter capsulatus ATCC11166.
Pharmaceutical composition heat of the present invention enters nutrient blood, excessive noxious heat, clearing away heat and cooling blood, relieves dizziness, high fever, infantile convulsions, epilepsy, etc. antipruritic.Cure mainly erythema squama, skin exfoliation dermatoses, psoriasis, argyraemia, psoriasis.
Detailed description of the invention
The present invention is further illustrated below by embodiment.It should be understood that embodiments of the invention are for illustration of the present invention instead of limitation of the present invention.Essence according to the present invention all belongs to the scope of protection of present invention to the simple modifications that the present invention carries out.Unless otherwise stated, the percent in the present invention is percetage by weight.
Embodiment 1
Take Concha Ostreae 30 grams, Carapax Trionycis 20 grams, stir-baked SQUAMA MANITIS 15 grams, Sanguis Draxonis 3 grams, Herba Artemisiae Scopariae 30 grams, Radix Gentianae 10 grams, Fructus Gardeniae 15 grams, Radix Scutellariae 15 grams, Rhizoma Imperatae 30 grams, Semen Plantaginis 30 grams, Rhizoma Alismatis 12 grams, Radix Bupleuri 10 grams, Radix Salviae Miltiorrhizae 30 grams, 20 grams, the Radix Rehmanniae, the Rhizoma Atractylodis Macrocephalae 15 grams, 20 grams, Poria, Radix Et Rhizoma Rhei 6 grams, Fructus Crataegi 15 grams, Fructus Chaenomelis 15 grams, 9 grams, Radix Rehmanniae Preparata, Rhizoma Sparganii 15 grams, Rhizoma Curcumae 15 grams, Fructus Ligustri Lucidi 30 grams, Radix Angelicae Sinensis 15 grams, Radix Paeoniae Rubra 15 grams, the Radix Paeoniae Alba 30 grams, Rhizoma Chuanxiong 15 grams, 10 grams, Semen Persicae, 10 grams, Flos Carthami, 10 grams, Pericarpium Citri Reticulatae Viride, Radix Notoginseng 6 grams, Pheretima 12 grams, Pericarpium Citri Reticulatae 10 grams, Radix Curcumae 15 grams, Fructus Lycii 15 grams, Fructus Aurantii 10 grams, Rhizoma Cyperi 10 grams, Fructus Setariae Germinatus 15 grams, 15 grams, Fructus Hordei Germinatus, Radix Codonopsis 30 grams, the Radix Astragali 30 grams and 10 grams, Radix Glycyrrhizae, add 100000 ml waters, heating 3 hours under the condition of backflow, filter, filtrate is made to be cooled to room temperature, then through the filtering with microporous membrane of 0.22 μm, obtain solution 1.
Embodiment 2
Take 7-(the fluoro-benzyloxy of 4-)-4,5-dihydro-2H-[1,2, the 4]-triazole [4,3-a] of 0.1 gram and quinoline-1-ketone, add 80000 ml sterile waters, ultrasonic 30 minutes, the then filtering with microporous membrane of 0.22 μm, obtains solution 2.
Bacteriostatic test
Use following compounds, adopt filter paper enzyme classical in this area to carry out bacteriostatic test.
For examination strain Rhodobacter capsulatus ATCC11166 purchased from Shanghai Kun Ken biochemical industry company limited.
Culture fluid
Nutrient agar and nutrient broth, purchased from Chen Yu experimental facilities company limited of BeiJing ZhongKe.
Test method
Rhodobacter capsulatus ATCC11166 is inoculated in agar plate nutritional solution plane, evenly gathers during inoculation.
The aseptic circular filter paper sheet of tweezer, spray the solution in the embodiment 2 of the solution+2.5ml in the embodiment 1 of the solution in the embodiment 2 of the solution in the embodiment 1 of 5ml, 5ml, 2.5ml respectively, to complete wetting, be attached in the agar plate nutritional solution plane of inoculated bacteria.Agar plate is placed in the incubator of 37 DEG C, incubation 4 hours.Measure the diameter of bacterial restrain.Measure and average for 3 times.
1.4 result
The average diameter of the bacterial restrain of the Rhodobacter capsulatus ATCC11166 of the solution in embodiment 1 is 11.35mm, the average diameter of the bacterial restrain of the Rhodobacter capsulatus ATCC11166 of the solution in embodiment 2 is 13.96mm, and the average diameter of the bacterial restrain of the Rhodobacter capsulatus ATCC11166 of the solution in the solution+embodiment 2 in embodiment 1 is 12.51.
Claims (5)
1. the dermopathic Chinese medicine composition for the treatment of, it is characterized in that, it comprises the material of following weight portion: Concha Ostreae 30 parts, Carapax Trionycis 20 parts, stir-baked SQUAMA MANITIS 15 parts, Sanguis Draxonis 3 parts, Herba Artemisiae Scopariae 30 parts, Radix Gentianae 10 parts, Fructus Gardeniae 15 parts, Radix Scutellariae 15 parts, Rhizoma Imperatae 30 parts, Semen Plantaginis 30 parts, Rhizoma Alismatis 12 parts, Radix Bupleuri 10 parts, Radix Salviae Miltiorrhizae 30 parts, 20 parts, the Radix Rehmanniae, the Rhizoma Atractylodis Macrocephalae 15 parts, 20 parts, Poria, Radix Et Rhizoma Rhei 6 parts, Fructus Crataegi 15 parts, Fructus Chaenomelis 15 parts, 9 parts, Radix Rehmanniae Preparata, Rhizoma Sparganii 15 parts, Rhizoma Curcumae 15 parts, Fructus Ligustri Lucidi 30 parts, Radix Angelicae Sinensis 15 parts, Radix Paeoniae Rubra 15 parts, the Radix Paeoniae Alba 30 parts, Rhizoma Chuanxiong 15 parts, 10 parts, Semen Persicae, 10 parts, Flos Carthami, 10 parts, Pericarpium Citri Reticulatae Viride, Radix Notoginseng 6 parts, Pheretima 12 parts, Pericarpium Citri Reticulatae 10 parts, Radix Curcumae 15 parts, Fructus Lycii 15 parts, Fructus Aurantii 10 parts, Rhizoma Cyperi 10 parts, Fructus Setariae Germinatus 15 parts, 15 parts, Fructus Hordei Germinatus, Radix Codonopsis 30 parts, the Radix Astragali 30 parts and 10 parts, Radix Glycyrrhizae.
2. the dermopathic Chinese medicine composition for the treatment of according to claim 1, is characterized in that, it also comprises the material of following weight portion: the 7-(the fluoro-benzyloxy of 4-)-4 of 0.1 part, 5-dihydro-2H-[1,2,4]-triazole [4,3-a] quinoline-1-ketone.
3. the dermopathic Chinese medicine composition for the treatment of according to claim 2, is characterized in that, described Chinese medicine composition can be tablet, dispersible tablet, capsule, pill or decoction.
4.7-(the fluoro-benzyloxy of 4-)-4,5-dihydro-2H-[1,2,4]-triazole [4,3-a] the quinoline-1-ketone purposes in the dermopathic medicine of preparation treatment.
5.7-(the fluoro-benzyloxy of 4-)-4,5-dihydro-2H-[1,2,4]-triazole [4,3-a] the quinoline-1-ketone purposes in the medicine of preparation vitro inhibition Rhodobacter capsulatus ATCC11166.
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| CN201510866586.4A CN105267891A (en) | 2015-11-27 | 2015-11-27 | Traditional Chinese medicine composition for treating skin diseases |
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| CN201510866586.4A CN105267891A (en) | 2015-11-27 | 2015-11-27 | Traditional Chinese medicine composition for treating skin diseases |
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105999068A (en) * | 2016-06-24 | 2016-10-12 | 苗刘存 | Traditional Chinese medicine for treating scars |
| CN105999067A (en) * | 2016-06-24 | 2016-10-12 | 苗刘存 | Traditional Chinese medicine reducing liquid (paste) for treating scars |
| CN110898136A (en) * | 2019-11-19 | 2020-03-24 | 安徽医科大学第一附属医院 | Traditional Chinese medicine composition for treating vitreous body and preparation method thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104177835A (en) * | 2014-09-19 | 2014-12-03 | 江阴海达橡塑股份有限公司 | Mildewproof rubber |
-
2015
- 2015-11-27 CN CN201510866586.4A patent/CN105267891A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104177835A (en) * | 2014-09-19 | 2014-12-03 | 江阴海达橡塑股份有限公司 | Mildewproof rubber |
Non-Patent Citations (2)
| Title |
|---|
| 刘卫兵等: ""从肝论治银屑病60例"", 《皮肤病与性病》 * |
| 师武青: ""中西医结合治疗银屑病55例临床观察"", 《青海医药杂志》 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105999068A (en) * | 2016-06-24 | 2016-10-12 | 苗刘存 | Traditional Chinese medicine for treating scars |
| CN105999067A (en) * | 2016-06-24 | 2016-10-12 | 苗刘存 | Traditional Chinese medicine reducing liquid (paste) for treating scars |
| CN110898136A (en) * | 2019-11-19 | 2020-03-24 | 安徽医科大学第一附属医院 | Traditional Chinese medicine composition for treating vitreous body and preparation method thereof |
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Application publication date: 20160127 |