CN105267677A - Traditional Chinese medicine composition containing rhizoma fagopyri dibotryis, indigowoad leaf and Chinese honeylocust fruit - Google Patents
Traditional Chinese medicine composition containing rhizoma fagopyri dibotryis, indigowoad leaf and Chinese honeylocust fruit Download PDFInfo
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- CN105267677A CN105267677A CN201510752660.XA CN201510752660A CN105267677A CN 105267677 A CN105267677 A CN 105267677A CN 201510752660 A CN201510752660 A CN 201510752660A CN 105267677 A CN105267677 A CN 105267677A
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Abstract
The invention relates to a traditional Chinese medicine composition containing rhizoma fagopyri dibotryis, indigowoad leaf and Chinese honeylocust fruit. The traditional Chinese medicine composition is prepared from 15-25 parts of rhizoma fagopyri dibotryis, 8-15 parts of indigowoad leaf, 10-15 parts of Chinese honeylocust fruit, 10-15 parts of almond, 16-22 parts of ephedra herb, 10-15 parts of radix platycodonis and 8-15 parts of common bletilla tuber. The traditional Chinese medicine composition can be powder and is prepared according to the steps of (1) weighing all traditional Chinese medicines according to the formula ratio; (2) grinding the traditional Chinese medicines and sifting the ground traditional Chinese medicines by a 30-80-mesh sift; (3) mixing for 5-15 minutes to obtain traditional Chinese medicine powder; (4) subpackaging the traditional Chinese medicine powder according to a standard of 50-200g per bag so as to obtain a finished product. The traditional Chinese medicine composition is prepared from the pure natural traditional Chinese medicines and capable of clearing heat, detoxifying, clearing the lung, eliminating phlegm, relieving cough and asthma and astringing to stop bleeding and can treat pulmonary tuberculosis of dogs effectively, and curative ratio is up to 85.7%.
Description
Technical field
The invention belongs to Chinese veterinary drug preparation field, especially a kind of Chinese medicine composition containing Rhizoma Fagopyri Dibotryis, Folium Isatidis and Fructus Gleditsia.
Background technology
Tuberculosis is the chronic infectious disease that a kind of people, animal caused by mycobacterium tuberculosis are suffered from altogether.Mycobacterium tuberculosis has cattle type, human-like and three kinds, fowl type, and dog, mainly to human-like and bacillus tuberculosis bovis is responsive, forms granuloma and cheesy calcification is feature in body Various Tissues.
The tuberculosis of dog is a kind of Chronic consumptions, all can fall ill throughout the year.Primary disease is different in size for incubation period, and relevant with administrative situation with age of dog, body constitution, nutrition, wherein 80% occur in pulmonary, other positions (as neck lymph, meninges, peritoneum, intestinal, skin, skeleton) also can secondary infection.Dog can through digestive tract, respiratory tract infection.The source of infection is the expectorant secretions such as people, cattle, dog, cat, the dust of pollution, feedstuff and the water that carry disease germs, through digestive tract, respiratory tract infection to health hosts.Become thin gradually after dog hectic, body body is weak, fatiguability, appetite obviously reduce, cough (dry cough or have thick sputum), spitting of blood, hectic fever, night sweat.Because its strain is at lung, therefore the phenomenon that after morbidity, common lung qi, deficiency of lung-YIN consume.
At present, the multiplex Western medicine for the treatment of pulmonary tuberculosis, conventional has Rimactazid, coordinates symptomatic treatment simultaneously, antipyretic, antitussive, strengthens nutrition, enhancing human body immunity power.But western medicine pulmonary tuberculosis exists more problem, one is that toxic and side effects is large; Two is that the resistance problems of tubercule bacillus to above-mentioned Western medicine highlights day by day, and curative effect is not fully up to expectations.China's natural resources of Chinese medicinal materials enriches, and can effectively avoid drug resistance and side-effect problem.Therefore treatment by Chinese herbs dog pulmonary tuberculosis how is utilized to be the new research direction in this area.
Summary of the invention
The problem to be solved in the present invention is: overcome the deficiencies in the prior art, provides a kind of evident in efficacy, cure rate is high, side effect is low Chinese medicine composition.
Another technical problem that the present invention will solve is: provide one to treat the phthisical Chinese medicine formula of dog.
Another technical problem that the present invention will solve is: the preparation method providing the powder of above-mentioned Chinese medicine composition.
For solving the problems of the technologies described above, the technical solution used in the present invention is: a kind of Chinese medicine composition containing Rhizoma Fagopyri Dibotryis, Folium Isatidis and Fructus Gleditsia, is characterized in that: be prepared from by the raw material of following mass fraction: Rhizoma Fagopyri Dibotryis 15 ~ 25 parts, Folium Isatidis 8 ~ 15 parts, 10 ~ 15 parts, Fructus Gleditsia, 10 ~ 16 parts, Semen Armeniacae Amarum, 16 ~ 22 parts, Herba Ephedrae, Radix Platycodonis 10 ~ 15 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 8 ~ 15 parts.
Further, the mass fraction of the optimum feed stock of this Chinese medicine composition is as follows: Rhizoma Fagopyri Dibotryis 22 parts, Folium Isatidis 10 parts, 12 parts, Fructus Gleditsia, 11 parts, Semen Armeniacae Amarum, 18 parts, Herba Ephedrae, Radix Platycodonis 15 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 12 parts.
Further, this Chinese medicine composition is the various conventional extract oral medicine dosage form containing or do not contain pharmaceutic adjuvant.
Further, described preparation can be powder.
Further, the preparation method of the powder of said composition is: (1) takes each Chinese medicine by formula ratio; (2) Chinese medicine is pulverized, cross 30-80 mesh sieve; (3) mix 5-15 minute and obtain Chinese medicine powder; (4) Chinese medicine powder is pressed every bag of 50-200g subpackage, get product.
The advantage that the present invention has and good effect are:
(1) this prescription chooses natural Chinese medicines raw material, green non-pollution, and non-evident effect.
(2) this prescription is according to tcm theory, and scientific compatibility, has effect of heat-clearing and toxic substances removing, removing heat from the lung and dissipating phlegm, relieving cough and asthma, astringing to arrest bleeding.Through Clinical Laboratory treatment dog pulmonary tuberculosis determined curative effect, cure rate reaches 85.7%.
(3) pharmacological action of each raw material of Chinese medicine of the present invention is:
Rhizoma Fagopyri Dibotryis: heat-clearing and toxic substances removing, evacuation of pus blood stasis dispelling;
Folium Isatidis: heat-clearing and toxic substances removing;
Fructus Gleditsia: pertinacious phlegm of dispelling, sensible opening and closing;
Semen Armeniacae Amarum: relieving cough and asthma;
Herba Ephedrae: relieving the exterior syndrome by diaphoresis, depressed lung-energy dispersing, inducing diuresis to remove edema;
Radix Platycodonis: lung qi dispersing, eliminate the phlegm, sore-throat relieving, evacuation of pus;
The Pseudobulbus Bletillae (Rhizoma Bletillae): astringing to arrest bleeding, detumescence and promoting granulation.
Among formula, Rhizoma Fagopyri Dibotryis is pungent cool, gets final product heat-clearing and toxic substances removing, again kind evacuation of pus blood stasis dispelling, and can removing heat from the lung and dissipating phlegm, therefore coughs up phlegm dense thick stench or cough vomiting bloody pus for its chief treat lung abscess, alone can be effective.In addition, Rhizoma Fagopyri Dibotryis also has the merit of strengthening the spleen to promote digestion, can control abdominal distention and little diet, the disease such as to become thin.Folium Isatidis bitter cold, kind separates excess-fire pyretic toxicity, enters again blood system and can cooling blood for hemostasis, with controlling carbuncle and ulcer, haematemesis, allly to hold concurrently malicious person with heat, all can use it.Fructus Gleditsia is pungent, salty, pungent can tonneau air flue, saltyly can soften cementing expectorant, therefore pertinacious phlegm glue hinders and sees cough with dyspnea in lung, time tell thick expectorant, being difficult to flat sleeping person with it, often should be equipped with Herba Ephedrae and controls cough with asthma abundant expectoration.Semen Armeniacae Amarum master enters lung meridian, and bitter in the mouth falls to be let out, and respectfully falls a surname that holds concurrently and sends out lung qi and can relieving cough and asthma, for controlling the key medicine of cough with asthma.The pungent loose hardship of Herba Ephedrae is let out, and Wen Tongxuan is smooth, main enter lung meridian, can the closing of external-open fur, smooth to make lung qi declare, inside fall the gas of superinverse, fall normal so that multiple lung department is respectful, therefore kindly to relieving asthma, the key medicine of breathing with cough caused by treatment sluggishness of lung-QI, and be often auxiliary with medicines for the treatment of cough and asthma such as Semen Armeniacae Amarums.Radix Platycodonis is bitter, pungent, flat, returns lung meridian, and its property is fallen apart up, can stop up the thick sputum of lung by sharp lung qi arrange, can control lung abscess and to cough chest pain, the disease such as stench of coughing up phlegm.Pseudobulbus Bletillae (Rhizoma Bletillae) medicine matter is extremely sticky, property pole astringent therapy, bitter in the mouth gas tremble with fear, be the key medicine of astringing to arrest bleeding, available control inside and outside all go out blood disorder.Enter lung meridian because it is main, lung hemostasis can be entered, control the card of spitting of blood.
Above-mentioned seven flavor medicine compatibility uses, and has effect of heat-clearing and toxic substances removing, removing heat from the lung and dissipating phlegm, relieving cough and asthma, astringing to arrest bleeding, is used for the treatment of dog pulmonary tuberculosis evident in efficacy.
Detailed description of the invention
Be further described the present invention below by specific embodiment, following examples are descriptive, are not determinate, can not limit protection scope of the present invention with this.
Embodiment 1
Containing a Chinese powder medicine for Rhizoma Fagopyri Dibotryis, Folium Isatidis and Fructus Gleditsia, the parts by weight of each raw material are as follows: Rhizoma Fagopyri Dibotryis 22 parts, Folium Isatidis 10 parts, 12 parts, Fructus Gleditsia, 11 parts, Semen Armeniacae Amarum, 18 parts, Herba Ephedrae, Radix Platycodonis 15 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 12 parts are prepared from.Its preparation method is: (1) takes each Chinese medicine by above-mentioned formula ratio; (2) Chinese medicine is pulverized, cross 60 mesh sieves; (3) mixing obtains Chinese medicine for 10 minutes and mixes powder; (4) Chinese medicine is mixed powder by every bag of 100g subpackage, get product.
Embodiment 2
Containing a Chinese powder medicine for Rhizoma Fagopyri Dibotryis, Folium Isatidis and Fructus Gleditsia, the parts by weight of each raw material are as follows: Rhizoma Fagopyri Dibotryis 15 parts, Folium Isatidis 12 parts, 15 parts, Fructus Gleditsia, 15 parts, Semen Armeniacae Amarum, 22 parts, Herba Ephedrae, Radix Platycodonis 11 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 10 parts are prepared from.Its preparation method is: (1) takes each Chinese medicine by above-mentioned formula ratio; (2) Chinese medicine is pulverized, cross 60 mesh sieves; (3) mixing obtains Chinese medicine for 10 minutes and mixes powder; (4) Chinese medicine is mixed powder by every bag of 100g subpackage, get product.
Embodiment 3
Containing a Chinese powder medicine for Rhizoma Fagopyri Dibotryis, Folium Isatidis and Fructus Gleditsia, the parts by weight of each raw material are as follows: Rhizoma Fagopyri Dibotryis 18 parts, Folium Isatidis 15 parts, 10 parts, Fructus Gleditsia, 12 parts, Semen Armeniacae Amarum, 16 parts, Herba Ephedrae, Radix Platycodonis 14 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 15 parts are prepared from.Its preparation method is: (1) takes each Chinese medicine by above-mentioned formula ratio; (2) Chinese medicine is pulverized, cross 60 mesh sieves; (3) mixing obtains Chinese medicine for 10 minutes and mixes powder; (4) Chinese medicine is mixed powder by every bag of 100g subpackage, get product.
Embodiment 4
Containing a Chinese powder medicine for Rhizoma Fagopyri Dibotryis, Folium Isatidis and Fructus Gleditsia, the parts by weight of each raw material are as follows: Rhizoma Fagopyri Dibotryis 20 parts, Folium Isatidis 11 parts, 13 parts, Fructus Gleditsia, 10 parts, Semen Armeniacae Amarum, 20 parts, Herba Ephedrae, Radix Platycodonis 13 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 13 parts are prepared from.Its preparation method is: (1) takes each Chinese medicine by above-mentioned formula ratio; (2) Chinese medicine is pulverized, cross 60 mesh sieves; (3) mixing obtains Chinese medicine for 10 minutes and mixes powder; (4) Chinese medicine is mixed powder by every bag of 100g subpackage, get product.
Embodiment 5
Containing a Chinese powder medicine for Rhizoma Fagopyri Dibotryis, Folium Isatidis and Fructus Gleditsia, the parts by weight of each raw material are as follows: Rhizoma Fagopyri Dibotryis 25 parts, Folium Isatidis 8 parts, 11 parts, Fructus Gleditsia, 16 parts, Semen Armeniacae Amarum, 22 parts, Herba Ephedrae, Radix Platycodonis 10 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 8 parts are prepared from.Its preparation method is: (1) takes each Chinese medicine by above-mentioned formula ratio; (2) Chinese medicine is pulverized, cross 60 mesh sieves; (3) mixing obtains Chinese medicine for 10 minutes and mixes powder; (4) Chinese medicine is mixed powder by every bag of 100g subpackage, get product.
Clinical trial
Experiment 1:
6 years old moral that People's Armed Police of Shandong Province raises herds bitch morbidity, occurs inappetence, is reluctant activity, and with dry cough symptom.Poultry raiser is not paid attention to.After first quarter moon, this dog aggravation, the bodily form is obviously become thin, and cough is frequent and with viscosity thick sputum, body temperature 38 DEG C.Go to a doctor immediately, get sputum, make smear, do acid-fast stain, microscopy, find that there is acid-fast stain positive bacillus.Pulmonary's percussion, there is dullness area local.Auscultation has obvious moist rales.X-ray checks, finds that there is dot-hatched not of uniform size.Tuberculin 0.1ml is injected in disease dog femoribus internus, after 36 hours, occurs positive reaction.According to sick dog clinical symptoms and characteristic inspection, tentative diagnosis is dog pulmonary tuberculosis.The powder that spice is fed obtained by the embodiment of the present invention 1 is immediately treated.According to the ratio spice decoction being taken at a draught of 3 ~ 5g powder/1Kg body weight, once a day.Continuous use is after 1 month, and sb.'s illness took a favorable turn for this dog, and cough number of times reduces, and temperature recovery is normal, and spirit greatly takes a turn for the better, and activity increases, and appetite increases.Continue medication 2 months, sick dog clinical symptoms all disappears, and no longer coughs, and freely, spirit and food-intake all recover normal, and body weight increases to some extent in activity.Check after half a year, do x-ray inspection, pulmonary loses shade, sick dog recovery from illness.
Test the powder treatment dog pulmonary tuberculosis that 1 result shows to use obtained by the embodiment of the present invention 1, good curative effect can be obtained.
Experiment 2
Kennel of Hebei province concentrates and has raised 15 kind dogs, and wherein a late September starts morbidity, and disease sees disease dog inappetence, easily tired, occasionally has dry cough.Initially treat according to flu, treated one week with penicillin, the state of an illness is not felt any better, and increases the weight of on the contrary.Sick dog lassitude, is reluctant activity, and the bodily form is gradually thin, and cough frequency increases and with thick sputum.With the tuberculin of purifying in sick dog femoribus internus intradermal injection 0.1ml, after 48 hours, find that there is obvious swelling disease dog injection site, there are necrosis in central authorities, are positive.Auscultation of lung has obvious moist rales.According to incidence and clinical observation and tuberculin inspection, tentative diagnosis is dog tuberculosis.Period finds that there is again 2 kind dogs and occurs symptoms such as coughing, listless.So check remaining 14 kind dog by tuberculin test method, have 6 assays for positive.Then by sick dog isolated rearing, feed with powder spice obtained by the embodiment of the present invention 1 and treat.According to the ratio spice decoction being taken at a draught of 3 ~ 5g powder/1Kg body weight, once a day, continuous use 1 month is a course for the treatment of.After the course for the treatment of, the state of an illness is controlled substantially, and sick dog spirit takes a turn for the better, and energy normal activity, cough frequency also obviously reduces.After continuing two courses for the treatment of of medication, above-mentioned clinical symptoms all disappears, and sick dog spirit and appetite all recover normal, and body weight increases to some extent.Do x-ray check, chest dot-hatched also all disappears.Except a sick dog because of older slaughter without rehabilitation sign buried except, all the other 6 sick dogs are all fully recovered, and cure rate reaches 85.7%.
The above, be only preferred embodiments of the present invention, is illustrative instead of determinate, can list several embodiments according to limited range, therefore in the change do not departed under general plotting of the present invention and amendment, should belong within protection scope of the present invention.
Claims (5)
1., containing a Chinese medicine composition for Rhizoma Fagopyri Dibotryis, Folium Isatidis and Fructus Gleditsia, it is characterized in that, be prepared from by the raw material of following mass fraction:
Rhizoma Fagopyri Dibotryis 15 ~ 25 parts, Folium Isatidis 8 ~ 15 parts, 10 ~ 15 parts, Fructus Gleditsia, 10 ~ 16 parts, Semen Armeniacae Amarum, 16 ~ 22 parts, Herba Ephedrae, Radix Platycodonis 10 ~ 15 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 8 ~ 15 parts.
2. a kind of Chinese medicine composition containing Rhizoma Fagopyri Dibotryis, Folium Isatidis and Fructus Gleditsia according to claim 1, is characterized in that: the mass fraction of optimum feed stock is as follows:
Rhizoma Fagopyri Dibotryis 22 parts, Folium Isatidis 10 parts, 12 parts, Fructus Gleditsia, 11 parts, Semen Armeniacae Amarum, 18 parts, Herba Ephedrae, Radix Platycodonis 15 parts, the Pseudobulbus Bletillae (Rhizoma Bletillae) 12 parts.
3. a kind of Chinese medicine composition containing Rhizoma Fagopyri Dibotryis, Folium Isatidis and Fructus Gleditsia according to claim 1 and 2, is characterized in that: this Chinese medicine composition be containing or various conventional extract oral medicine dosage form not containing pharmaceutic adjuvant.
4. a kind of Chinese medicine composition containing Rhizoma Fagopyri Dibotryis, Folium Isatidis and Fructus Gleditsia according to claim 3, is characterized in that: described preparation can be powder.
5. prepare a method for a kind of Chinese powder medicine containing Rhizoma Fagopyri Dibotryis, Folium Isatidis and Fructus Gleditsia as claimed in claim 4, it is characterized in that, preparation method is: (1) takes each Chinese medicine by formula ratio; (2) Chinese medicine is pulverized, cross 30-80 mesh sieve; (3) mix 5-15 minute and obtain Chinese medicine powder; (4) Chinese medicine powder is pressed every bag of 50-200g subpackage, get product.
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010044042A1 (en) * | 2008-10-14 | 2010-04-22 | Manuka Health New Zealand Limited | Antimicrobial compositions |
| CN103599375A (en) * | 2013-11-26 | 2014-02-26 | 张永平 | Medicament for treating tuberculosis |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2010044042A1 (en) * | 2008-10-14 | 2010-04-22 | Manuka Health New Zealand Limited | Antimicrobial compositions |
| CN103599375A (en) * | 2013-11-26 | 2014-02-26 | 张永平 | Medicament for treating tuberculosis |
Non-Patent Citations (6)
| Title |
|---|
| 中央爱国卫生运动委员会等: "《肺结核病防治指南》", 30 June 1984 * |
| 司晓文: "《抗细菌中草药及处方》", 30 April 2012 * |
| 夏丽英: "《中药毒性手册》", 30 November 2006 * |
| 李世文等: "《一味中药祛顽疾》", 30 September 2014 * |
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