CN105267060A - Silver-based anti-dandruff shampoo and preparation method thereof - Google Patents

Silver-based anti-dandruff shampoo and preparation method thereof Download PDF

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Publication number
CN105267060A
CN105267060A CN201510806339.5A CN201510806339A CN105267060A CN 105267060 A CN105267060 A CN 105267060A CN 201510806339 A CN201510806339 A CN 201510806339A CN 105267060 A CN105267060 A CN 105267060A
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CN
China
Prior art keywords
ammonium salt
polyquaternary ammonium
parts
collargol
shampoo containing
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201510806339.5A
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Chinese (zh)
Inventor
朱翔
杨涛
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Yangzhou Zhongfu Biotechnology Co Ltd
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Yangzhou Zhongfu Biotechnology Co Ltd
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Publication date
Application filed by Yangzhou Zhongfu Biotechnology Co Ltd filed Critical Yangzhou Zhongfu Biotechnology Co Ltd
Priority to CN201510806339.5A priority Critical patent/CN105267060A/en
Publication of CN105267060A publication Critical patent/CN105267060A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/73Polysaccharides
    • A61K8/732Starch; Amylose; Amylopectin; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/19Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/006Antidandruff preparations
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/02Preparations for cleaning the hair
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/20Chemical, physico-chemical or functional or structural properties of the composition as a whole
    • A61K2800/30Characterized by the absence of a particular group of ingredients

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Inorganic Chemistry (AREA)
  • Cosmetics (AREA)

Abstract

The invention discloses a silver-based anti-dandruff shampoo and a preparation method thereof. The silver-based anti-dandruff shampoo is prepared from by weight: colloid sliver 1-2 parts, disodium EDTA 0.01-1 part, carbomer 0.5-1 part, ammonium dodecyl poly oxyethylene sulfate 15-18 parts, glycerol distearate 2-3 parts, cocoyl monoethanolamine 1-2 parts, pullulan 3-5 parts, polyquaternium-7 3-5 parts, polyquaternium-47 0.1-0.5 part, sodium chloride 3-4 parts, an essence 0.1-0.2 part, and deionized water 60-70 parts. The silver-based anti-dandruff shampoo has a scientific and reasonable formula, the use of a preservative is avoided by adding the colloid sliver and pullulan, no damage is caused to hair in long-term usage, and the shampoo has good anti-dandruff and moisturizing effects.

Description

A kind of money base dandruff control shampoo containing and preparation method thereof
Technical field
The invention belongs to cosmetic field, be specifically related to a kind of money base dandruff control shampoo containing and preparation method thereof.
Background technology
Dandruff is usually grown by the Malassezia furfur being nutrition with the cortex of scalp and causes producing.Dandruff control shampoo containing on market generally uses ketoconazole or Zinc Pyrithione as anti-dandruff agent, and the dandruff control shampoo containing on market is all containing antiseptic, and life-time service can have side effects to human body.Silver is a kind of safe physical sterilization agent, produces bactericidal effect by destroying the internal structure of antibacterial and fungus.Pulullan polysaccharide is a kind of safe fermentation polysaccharides, can form protecting film and give hair good smooth feeling in hair surface.By pulullan polysaccharide and collargol used in combination, be first that it two can play each own effect; Secondly, by pulullan polysaccharide as carrier, collargol can be wrapped, extends the time of staying of collargol on hair, play long-time bactericidal effect.The dandruff control shampoo containing being not main component with collargol, pulullan polysaccharide on the market at present.
Summary of the invention
Goal of the invention the present invention, in order to solve the deficiencies in the prior art, provides one to have well anti-dandruff, nourishing effect, not dandruff control shampoo containing adding antiseptic and preparation method thereof.
The technical solution used in the present invention for this reason: a kind of money base dandruff control shampoo containing; formulated by collargol, EDTA-disodium, carbomer, lauryl polyethenoxy ether sodium sulfate, glycerol distearate, cocoyl monoethanolamine, pulullan polysaccharide, polyquaternary ammonium salt-7, polyquaternary ammonium salt-47, sodium chloride, essence, deionized water, the mass fraction ratio of described each component is:
Collargol 1-2 part;
EDETATE SODIUM 0.01-0.1 part;
Carbomer 0.5-1 part;
Lauryl polyethenoxy ether sodium sulfate 15-18 part;
Glycerol distearate 2-3 part;
Cocoyl monoethanolamine 1-2 part;
Pulullan polysaccharide 3-5 part;
Polyquaternary ammonium salt-73-5 part;
Polyquaternary ammonium salt-470.1-0.5 part;
Sodium chloride 3-4 part;
Essence 0.1-0.2 part;
Deionized water 60-70 part.
Wherein:
Collargol: silver granuel footpath, mostly at 25 ran, is between 20-30nm specifically, has strong suppression and killing action, and can not produce drug resistance to tens of kinds of pathogenic microorganism such as escherichia coli, gonococcus, chlamydia trachomatiss.
Pulullan polysaccharide: pulullan polysaccharide is a kind of biological polyoses, is widely applied to now in the middle of cosmetics, promotes cell regeneration, and alternative hyaluronic acid is used for moisturizing antioxidation etc., belongs to natural health cosmetic material.
Beneficial effect of the present invention: dandruff control shampoo containing scientific formulation provided by the invention is reasonable, and by adding collargol and pulullan polysaccharide, avoid use antiseptic, life-time service, to hair not damaged, has good anti-dandruff and moisturizing effect.
Detailed description of the invention:
Because of carbomer comparatively indissoluble solution under the existence of other materials, first spread on the water surface by carbomer 1 gram, stir to obtain major ingredient body be heated to 75 DEG C ~ 80 DEG C, then adds other raw material successively.
Example one:
(1) add deionized water 60 grams and EDETATE SODIUM 0.1 gram under room temperature in a reservoir, start to stir.Under stirring at low speed, spread on the water surface by carbomer 1 gram, stir to obtain major ingredient body be heated to 75 DEG C ~ 80 DEG C;
(2) add lauryl polyethenoxy ether sodium sulfate 15 grams, glycerol distearate 2 grams, cocoyl monoethanolamine 1 gram, pulullan polysaccharide 4 grams successively in major ingredient body, be uniformly mixed;
(3) lower cooling material body is stirred to room temperature.Add polyquaternary ammonium salt-73 grams, polyquaternary ammonium salt-470.2 grams, collargol 1 gram, 3 grams, sodium chloride, 0.1 gram, essence successively, mix and blend after 1 hour moisturizing to 100g i.e. obtained described money base dandruff control shampoo containing.
Example two:
(1) add deionized water 59 grams and EDETATE SODIUM 0.1 gram under room temperature in a reservoir, start to stir.Under stirring at low speed, spread on the water surface by carbomer 1 gram, stir to obtain major ingredient body be heated to 75 DEG C ~ 80 DEG C;
(2) add lauryl polyethenoxy ether sodium sulfate 15 grams, glycerol distearate 2 grams, cocoyl monoethanolamine 1 gram, pulullan polysaccharide 5 grams successively in major ingredient body, be uniformly mixed;
(3) lower cooling material body is stirred to room temperature.Add polyquaternary ammonium salt-73 grams, polyquaternary ammonium salt-470.2 grams, collargol 1 gram, 3 grams, sodium chloride, 0.1 gram, essence successively, mix and blend after 1 hour moisturizing to 100g i.e. obtained described money base dandruff control shampoo containing.
Example three:
(1) add deionized water 59.5 grams and EDETATE SODIUM 0.1 gram under room temperature in a reservoir, start to stir.Under stirring at low speed, spread on the water surface by carbomer 1 gram, stir to obtain major ingredient body be heated to 75 DEG C ~ 80 DEG C;
(2) add lauryl polyethenoxy ether sodium sulfate 15 grams, glycerol distearate 2 grams, cocoyl monoethanolamine 1 gram, pulullan polysaccharide 4 grams successively in major ingredient body, be uniformly mixed;
(3) lower cooling material body is stirred to room temperature.Add polyquaternary ammonium salt-73 grams, polyquaternary ammonium salt-470.2 grams, collargol 1.5 grams, 3 grams, sodium chloride, 0.1 gram, essence successively, mix and blend after 1 hour moisturizing to 100g i.e. obtained described money base dandruff control shampoo containing.
Embodiment is to the effect after hair washing
(wherein microbiological contamination amount adopts ordinary nutrient agar mounting method: ordinary nutrient agar sticks 30s on the hair after cleaning, and dries, is placed in the incubator of 37 DEG C and cultivates 48h, then add up clump count)
Before using Example one Example two Example three
2h moisture retention (%) 13.4 15.9 16.8 15.6
24h microbiological contamination amount (cfu/cm2) 57.07 24.7 25.4 21.1

Claims (4)

1. a money base dandruff control shampoo containing; it is characterized in that, formulated by collargol, EDTA-disodium, carbomer, lauryl polyethenoxy ether sodium sulfate, glycerol distearate, cocoyl monoethanolamine, pulullan polysaccharide, polyquaternary ammonium salt-7, polyquaternary ammonium salt-47, sodium chloride, essence, deionized water.
2. a kind of money base dandruff control shampoo containing according to claim 1, is characterized in that, the mass ratio of each component is:
Collargol 1-2 part;
EDETATE SODIUM 0.01-0.1 part;
Carbomer 0.5-1 part;
Lauryl polyethenoxy ether sodium sulfate 15-18 part;
Glycerol distearate 2-3 part;
Cocoyl monoethanolamine 1-2 part;
Pulullan polysaccharide 3-5 part;
Polyquaternary ammonium salt-73-5 part;
Polyquaternary ammonium salt-470.1-0.5 part;
Sodium chloride 3-4 part;
Essence 0.1-0.2 part;
Deionized water 60-70 part.
3. a kind of money base dandruff control shampoo containing according to claim 1, is characterized in that, described collargol particle diameter is at 20-30nm.
4. a preparation method for money base dandruff control shampoo containing, is characterized in that, carries out according to following steps:
1) add deionized water and EDETATE SODIUM in a reservoir under room temperature, start to stir; Under stirring at low speed, spread by carbomer on the water surface, stir to obtain major ingredient body be heated to 75 DEG C ~ 80 DEG C;
2) add lauryl polyethenoxy ether sodium sulfate, glycerol distearate, cocoyl monoethanolamine, pulullan polysaccharide successively in major ingredient body, be uniformly mixed;
3) stir lower cooling material body to room temperature, add polyquaternary ammonium salt-7, polyquaternary ammonium salt-47, collargol, sodium chloride, essence successively, moisturizing i.e. obtained described money base dandruff control shampoo containing after mix and blend 0.8-1.5 hour.
CN201510806339.5A 2015-11-20 2015-11-20 Silver-based anti-dandruff shampoo and preparation method thereof Pending CN105267060A (en)

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Application Number Priority Date Filing Date Title
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Publication Number Publication Date
CN105267060A true CN105267060A (en) 2016-01-27

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107184418A (en) * 2017-04-06 2017-09-22 山东省药学科学院 A kind of hair conditioner of pullulan-containing
CN113397994A (en) * 2021-07-08 2021-09-17 珠海博御中医药研究有限公司 Cosmetic additive and preparation method and application thereof
CN113398029A (en) * 2021-07-08 2021-09-17 珠海博御中医药研究有限公司 Antibacterial and anti-dandruff shampoo and preparation method thereof
US11319566B2 (en) 2017-04-14 2022-05-03 Capsugel Belgium Nv Process for making pullulan
US11576870B2 (en) 2017-04-14 2023-02-14 Capsugel Belgium Nv Pullulan capsules

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101516321A (en) * 2006-08-24 2009-08-26 生物医学解决方案公司 Aqueous sanitizers, disinfectants, and/or sterilants with low peroxygen content
CN102125508A (en) * 2010-01-19 2011-07-20 上海华银日用品有限公司 Hair-treating and anti-dandruff shampoo and preparation method thereof
CN103251514A (en) * 2013-05-22 2013-08-21 江苏隆力奇生物科技股份有限公司 Anti-dandruff shampoo composition

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101516321A (en) * 2006-08-24 2009-08-26 生物医学解决方案公司 Aqueous sanitizers, disinfectants, and/or sterilants with low peroxygen content
CN102125508A (en) * 2010-01-19 2011-07-20 上海华银日用品有限公司 Hair-treating and anti-dandruff shampoo and preparation method thereof
CN103251514A (en) * 2013-05-22 2013-08-21 江苏隆力奇生物科技股份有限公司 Anti-dandruff shampoo composition

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107184418A (en) * 2017-04-06 2017-09-22 山东省药学科学院 A kind of hair conditioner of pullulan-containing
US11319566B2 (en) 2017-04-14 2022-05-03 Capsugel Belgium Nv Process for making pullulan
US11576870B2 (en) 2017-04-14 2023-02-14 Capsugel Belgium Nv Pullulan capsules
US11878079B2 (en) 2017-04-14 2024-01-23 Capsugel Belgium Nv Pullulan capsules
CN113397994A (en) * 2021-07-08 2021-09-17 珠海博御中医药研究有限公司 Cosmetic additive and preparation method and application thereof
CN113398029A (en) * 2021-07-08 2021-09-17 珠海博御中医药研究有限公司 Antibacterial and anti-dandruff shampoo and preparation method thereof
CN113397994B (en) * 2021-07-08 2022-03-15 珠海博御中医药研究有限公司 Cosmetic additive and preparation method and application thereof

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Application publication date: 20160127