CN105250825B - A kind of Chinese medicine composition treating and preventing livestock and poultry and fur-bearing animal gastroenteritis - Google Patents
A kind of Chinese medicine composition treating and preventing livestock and poultry and fur-bearing animal gastroenteritis Download PDFInfo
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Abstract
The invention belongs to technical field of traditional Chinese medicines, in particular to a kind of Chinese medicine composition for treating and preventing livestock and poultry and fur-bearing animal gastroenteritis.In parts by weight, the composition is made of following bulk drugs: 5-25 parts of Divine Comedy, 10-35 parts of malt, 10-35 parts of dried orange peel, 5-25 parts of Fructus Aurantii, 10-30 parts of Radix Codonopsis, 5-25 parts of Radix Astragali, 10-35 parts of dark plum, 10-40 parts of myrobalan, 10-40 parts of alum, 10-40 parts of the coptis, 10-35 parts of garden burnet, 10-45 parts of Fructus Forsythiae, 10-45 parts of honeysuckle, 10-40 parts of Radix Glycyrrhizae.The Chinese medicine composition of the present invention for treating and preventing livestock and poultry and fur-bearing animal gastroenteritis, compatibility is reasonable, safely and effectively, and treating both manifestation and root cause of disease, no recurrence, effective percentage up to 94.32% or more.
Description
Technical field
The invention belongs to technical field of traditional Chinese medicines, in particular in a kind for the treatment of and prevention livestock and poultry and fur-bearing animal gastroenteritis
Drug composition.
Background technique
Gastroenteritis refers to that causing gastrointestinal mucosa to be inflamed by various factors sexually revises, and is divided to acute and chronic two according to the course of disease
Kind, it is chronic relatively common.Cause gastroenteritis factor very much, as viral disease infection, bacterial infection, mycotoxin infection and
Environmental factor etc..Such as the currently a popular proventriculitis of poultry, ventriculitis, caused by bacillary enteritis, viral enteritis, mycotoxin
Alimentary infection etc.；Pig virus diarrhoea such as epidemic diarrhea, transmissible gastroenteritis etc., piglet red dysentery caused by bacterium infection,
Piglet Huang, dysentery characterized by white mucous stool, dysentery, gastrointestinal tract inflammation caused by mycotoxin etc.；Caused by Escherichia coli, detection of Salmonella, Pasteurella etc.
The gastroenteritis etc. of fur-bearing animal.Livestock and poultry and fur-bearing animal gastroenteritis have become the important diseases for restricting aquaculture development at present.
Gastroenteritis generally takes Western medicine to be treated, but western medicine irritation is big, easily repeatedly, is unable to treating both manifestation and root cause of disease.
Summary of the invention
The object of the present invention is to provide a kind for the treatment of and prevention livestock and poultry and the Chinese medicine compositions of fur-bearing animal gastroenteritis, use
Chinese medicine treatment gastroenteritis, treating both manifestation and root cause of disease, and it is without side-effects.
The technical solution adopted by the invention is as follows:
A kind of Chinese medicine composition treating and preventing livestock and poultry and fur-bearing animal gastroenteritis, in parts by weight, the composition
It is made of following bulk drugs: 5-25 parts of Divine Comedy, 10-35 parts of malt, 10-35 parts of dried orange peel, 5-25 parts of Fructus Aurantii, 10-30 parts of Radix Codonopsis, Huang
5-25 parts of stilbene, 10-35 parts of dark plum, 10-40 parts of myrobalan, 10-40 parts of alum, 10-40 parts of the coptis, 10-35 parts of garden burnet, Fructus Forsythiae 10-
45 parts, 10-45 parts of honeysuckle, 10-40 parts of Radix Glycyrrhizae.
Preferably, raw material medicines in portions by weight composition is as follows: 10-15 parts of Divine Comedy, 15-25 parts of malt, 15-22 parts of dried orange peel,
8-15 parts of Fructus Aurantii, 15-25 parts of Radix Codonopsis, 10-15 parts of Radix Astragali, 16-25 parts of dark plum, 18-30 parts of myrobalan, 20-30 parts of alum, the coptis
20-30 parts, 16-28 parts of garden burnet, 25-36 parts of Fructus Forsythiae, 25-36 parts of honeysuckle, 20-30 parts of Radix Glycyrrhizae.
More preferably, the raw material medicines in portions by weight composition is as follows: 12.5 parts of Divine Comedy, 20 parts of malt, 18.5 parts of dried orange peel, trifoliate orange
11.5 parts of shell, 20 parts of Radix Codonopsis, 12.5 parts of Radix Astragali, 20.5 parts of dark plum, 24 parts of myrobalan, 25 parts of alum, 25 parts of the coptis, 22 parts of garden burnet,
30.5 parts of Fructus Forsythiae, 30.5 parts of honeysuckle, 25 parts of Radix Glycyrrhizae.
In bulk pharmaceutical chemicals of the present invention, it is monarch that Divine Comedy, malt, dried orange peel, Fructus Aurantii, Radix Codonopsis and Radix Astragali tonifying spleen appetizing, which improve immunity,
Medicine；Dark plum, myrobalan, alum astringing to arrest bleeding are ministerial drug；The coptis, garden burnet play heat-clearing, removing toxic substances, antibacterial, anti-inflammatory, Fructus Forsythiae, gold
Honeysuckle flower removing dampness and destroying parasites, absorbing toxin, there is detoxicating functions, are adjutant；Radix Glycyrrhizae mediation property of medicine is to make medicine.The above all medicines share, is played altogether
Clearing heat and detoxicating, activating microcirculation and removing stasis medicinal restrains anti-inflammatory, and stomach invigorating disinfects the effect of plain, prevents and treats gastroenteritis significant effect.
Acceptable various dosage forms in pharmacy can be conventionally made in above-mentioned raw materials medicine, can such as be made into according to demand
A variety of dosage forms such as oral solution, tablet, pill, paste, pulvis, pre-mixing agent.The Chinese medicine composition, both can be with when specifically used
It is used as drug, can also be used as additive use, be also used as the carrier of premix.It is treated and prevented using the present invention
The Chinese medicine composition of livestock and poultry and fur-bearing animal gastroenteritis, by taking bulk pharmaceutical chemicals smash it through the pulvis of 300 meshes as an example, dosage is according to fowl
0.5-2.0g/, rabbit 3-6g/, fur-bearing animal (such as fox, ermine, racoon dog) 7.5-15g/, ox 150-200g/ head, sheep, pig
30-50g/ head, after drug boiling 30 minutes of sieving, medical fluid drinking-water, dregs of a decoction spice or medical fluid and the dregs of a decoction spice simultaneously, even
It is efficient up to 94.32% or more with 5-7 days, and without recurrence；When prevention, dosage halves, and prevention rate is up to 96.7%.
Compared with the prior art, the invention has the following advantages:
The Chinese medicine composition of the present invention for treating and preventing livestock and poultry and fur-bearing animal gastroenteritis, compatibility is reasonable, has safely
Effect, and treating both manifestation and root cause of disease, no recurrence, treated effect are up to 94.32% or more, and prevention rate is up to 96.7%.
Specific embodiment
Below the technical scheme of the invention is illustrated by a specific example, but the scope of the present invention is not limited thereto:
Embodiment 1
A kind of Chinese medicine composition treating and preventing livestock and poultry and fur-bearing animal gastroenteritis, in parts by weight, bulk pharmaceutical chemicals composition
It is as follows:
10 parts of Divine Comedy, 15 parts of malt, 15 parts of dried orange peel, 8 parts of Fructus Aurantii, 15 parts of Radix Codonopsis, 10 parts of Radix Astragali, 16 parts of dark plum, myrobalan 18
Part, 20 parts of alum, 20 parts of the coptis, 16 parts of garden burnet, 25 parts of Fructus Forsythiae, 25 parts of honeysuckle, 20 parts of Radix Glycyrrhizae.
Above-mentioned raw materials medicine is smashed it through into 300 meshes up to the Chinese medicine composition.
Embodiment 2
A kind of Chinese medicine composition treating and preventing livestock and poultry and fur-bearing animal gastroenteritis, in parts by weight, bulk pharmaceutical chemicals composition
It is as follows:
12.5 parts of Divine Comedy, 20 parts of malt, 18.5 parts of dried orange peel, 11.5 parts of Fructus Aurantii, 20 parts of Radix Codonopsis, 12.5 parts of Radix Astragali, dark plum
20.5 parts, 24 parts of myrobalan, 25 parts of alum, 25 parts of the coptis, 22 parts of garden burnet, 30.5 parts of Fructus Forsythiae, 30.5 parts of honeysuckle, 25 parts of Radix Glycyrrhizae.
Above-mentioned raw materials medicine is smashed it through into 300 meshes up to the Chinese medicine composition.
Embodiment 3
A kind of Chinese medicine composition treating and preventing livestock and poultry and fur-bearing animal gastroenteritis, in parts by weight, bulk pharmaceutical chemicals composition
It is as follows:
15 parts of Divine Comedy, 25 parts of malt, 22 parts of dried orange peel, 15 parts of Fructus Aurantii, 25 parts of Radix Codonopsis, 15 parts of Radix Astragali, 25 parts of dark plum, myrobalan 30
Part, 30 parts of alum, 30 parts of the coptis, 28 parts of garden burnet, 36 parts of Fructus Forsythiae, 36 parts of honeysuckle, 30 parts of Radix Glycyrrhizae.
Above-mentioned raw materials medicine is smashed it through into 300 meshes up to the Chinese medicine composition.
Embodiment 4
A kind of Chinese medicine composition treating and preventing livestock and poultry and fur-bearing animal gastroenteritis, in parts by weight, bulk pharmaceutical chemicals composition
It is as follows:
15 parts of Divine Comedy, 15 parts of malt, 15 parts of dried orange peel, 10 parts of Fructus Aurantii, 10 parts of Radix Codonopsis, 10 parts of Radix Astragali, 15 parts of dark plum, myrobalan 10
Part, 15 parts of alum, 10 parts of the coptis, 20 parts of garden burnet, 10 parts of Fructus Forsythiae, 10 parts of honeysuckle, 10 parts of Radix Glycyrrhizae.
Above-mentioned raw materials medicine is smashed it through into 300 meshes up to the Chinese medicine composition.
Embodiment 5
A kind of Chinese medicine composition treating and preventing livestock and poultry and fur-bearing animal gastroenteritis, in parts by weight, bulk pharmaceutical chemicals composition
It is as follows:
12.5 parts of Divine Comedy, 12.5 parts of malt, 12.5 parts of dried orange peel, 12.5 parts of Fructus Aurantii, 10 parts of Radix Codonopsis, 12.5 parts of Radix Astragali, dark plum
20 parts, 15 parts of myrobalan, 15 parts of alum, 10 parts of the coptis, 25 parts of garden burnet, 15 parts of Fructus Forsythiae, 10 parts of honeysuckle, 10 parts of Radix Glycyrrhizae.
Above-mentioned raw materials medicine is smashed it through into 300 meshes up to the Chinese medicine composition.
Embodiment 6
A kind of Chinese medicine composition treating and preventing livestock and poultry and fur-bearing animal gastroenteritis, in parts by weight, bulk pharmaceutical chemicals composition
It is as follows:
5 parts of Divine Comedy, 10 parts of malt, 10 parts of dried orange peel, 5 parts of Fructus Aurantii, 10 parts of Radix Codonopsis, 5 parts of Radix Astragali, 10 parts of dark plum, 10 parts of myrobalan,
10 parts of alum, 10 parts of the coptis, 10 parts of garden burnet, 10 parts of Fructus Forsythiae, 10 parts of honeysuckle, 10 parts of Radix Glycyrrhizae.
Above-mentioned raw materials medicine is smashed it through into 300 meshes up to the Chinese medicine composition.
Embodiment 7
A kind of Chinese medicine composition treating and preventing livestock and poultry and fur-bearing animal gastroenteritis, in parts by weight, bulk pharmaceutical chemicals composition
It is as follows:
25 parts of Divine Comedy, 35 parts of malt, 35 parts of dried orange peel, 25 parts of Fructus Aurantii, 30 parts of Radix Codonopsis, 25 parts of Radix Astragali, 35 parts of dark plum, myrobalan 40
Part, 40 parts of alum, 40 parts of the coptis, 35 parts of garden burnet, 45 parts of Fructus Forsythiae, 45 parts of honeysuckle, 40 parts of Radix Glycyrrhizae.
Above-mentioned raw materials medicine is smashed it through into 300 meshes up to the Chinese medicine composition.
Effect example
The traditional chinese medicine composition of the invention achieves good curative effect with clinical case is controlled.By taking 1 Chinese medicine composition of embodiment as an example,
It is for oral administration as additive spice: when treatment, the big domestic animal such as ox, horse and camel: 200-500g/ head；Pig, sheep: 50-100g/
Head, fox, racoon dog, ermine: only, fowl: only, rabbit: 3-6 g/ only, counts curative effect after being used in conjunction 5 days to 0.5-2.0g/ to 10-30g/.If with
Halve in preventive dose.
Efficacy determination: protective rate is considered as effectively 96.0% or more when prevention.When treatment, take medicine 5, symptom eliminates, 7 days
Inside not repeatedly, it is considered as healing；It is asymptomatic in 10 days, it is considered as effectively, it is invalid to be otherwise considered as.See Table 1 for details for therapeutic effect.
Table 1
| Poultry kind | Morbidity (head, only) number | Cure (head, only) number | Cure rate (%) | Effectively (head, only) number | Efficient (%) |
| Fowl | 1227600 | 1138845 | 92.77 | 1181074 | 96.21 |
| Pig | 1860 | 1658 | 89.14 | 1762 | 94.73 |
| Ox | 526 | 471 | 89.54 | 501 | 95.24 |
| Horse | 7 | 6 | 85.71 | 7 | 100.00 |
| Sheep | 756 | 681 | 90.08 | 717 | 94.84 |
| Fox | 453 | 406 | 89.62 | 428 | 94.48 |
| Ermine | 182 | 159 | 87.36 | 172 | 94.51 |
| Racoon dog | 326 | 295 | 90.49 | 308 | 94.48 |
| Rabbit | 485 | 441 | 90.93 | 457 | 94.23 |
Effect example 1
In June, 2014, the AA broiler chicken of 20000 12 ages in days of Henan Province Suixian County Zhang raising, sudden onset, disease is just
Individual chicken lassitudes, for crop without food, wing is sagging, stays and stands, then diarrhea, draws green material excrement, and feed intake declines, and growth is slow
It is slow, uniformity difference etc..The visible glandular stomach enlargement such as ball of pathological change, is creamy white or canescence trellis appearance；Glandular stomach wall thickening, water
Swollen, the swelling of glandular stomach mucous membrane thickens, and nipple swelling, bleeding, ulcer, part nipple have merged, and boundary is unclear, and enteron aisle has hemorrhagic
The symptoms such as enteritis.Chicken infectious provenculitis is diagnosed as according to clinical symptoms and pathological change.
Chinese medicine composition after the sieving of Example 2 is according to 0.75 gram/of dosage, and after boiling 30 minutes, medical fluid is drunk
Water, dregs of a decoction spice, 92.75% diseased chicken symptom completely disappears after being used in conjunction 5 days, 5 days, has no in 7 days repeatedly, and disease must be cured, and 10
Restore after it normal.
Effect example 2
In October, 2014, the AA broiler chicken of 15000 7 ages in days of Liaoning Province Qing Yuanxian Mr. Wang raising, individual chicken spirit
Depressed, feather is fluffy, closes one's eyes, is slow-witted vertical, draws green or white loose stool, and feed intake decline, amount of drinking water is reduced, after morbidity 5 days, jumpbogroup
Feed intake decline, amount of drinking water decline, diarrhea draw material excrement, occur the respiratory symptoms such as snore individually, and death occur.Pathology becomes
Change visible glandular stomach enlargement, glandular stomach wall thickening, oedema, the swelling of glandular stomach mucous membrane thickens, nipple swelling, bleeding, ulcer, part nipple
It has been merged that, boundary is unclear；When serious, glandular stomach is thinning, and ulcer, perforation, muscular stomach atrophy, cuticula occur in glandular stomach and muscular stomach intersection
It is easy to fall off, the symptoms such as hemorrhagic enteritis.Proventriculitis, ventriculitis are diagnosed as according to clinical symptoms and pathological change.
Chinese medicine composition after the sieving of Example 1, according to 0.5 gram/of dosage, after boiling 30 minutes, medical fluid drink
Water, dregs of a decoction spice, 93.60% diseased chicken symptom completely disappears after being used in conjunction 5 days, 5 days, has no in 7 days repeatedly, and disease must be cured, and 10
Restore after it normal.
Effect example 3
There is fragmentary morbidity and death suddenly in December, 2014,40000 Laying chicks of 38 ages in days that Nanyang Deng raises
Phenomenon, only a few chicken is apathetic, and wing is sagging, stays and stands, peels off, crop is without feed；Feed intake is begun to decline after 5 days, drinking-water
Amount decline, diarrhea is unobvious, and then death is begun to ramp up, and has loose bowels, and part chicken body situation is not of uniform size, chicken syntexis etc. of dying of illness.Disease
Reason, which changes, is mainly shown as glandular stomach, glandular stomach swelling, mucous membrane swelling, nipple swelling, bleeding, and glandular stomach muscular stomach intersection broadens, is thinning,
It perforates when serious, easy to fall off, ulcer of cuticula etc., small intestine flatulence, intestinal wall is thinning to wait diseases.According at the beginning of clinical symptoms and pathological change
It examines as chicken infectious provenculitis.
Chinese medicine composition after the sieving of Example 4, according to 1.0 grams/of dosage, after boiling 30 minutes, medical fluid drink
Water, dregs of a decoction spice, 95.60% diseased chicken symptom completely disappears after being used in conjunction 5 days, 5 days, has no in 7 days repeatedly, and disease must be cured, and 10
Restore after it normal.
Embodiment 4
In March, 2015, Henan Province Xiping County Lee raise the externally-purchased piglet sudden onset of 326 61 ages in days, have loose bowels, excrement
Mostly black or brown, coat is thick disorderly, matt, slight to have a fever, and does not eat, down in spirits, individual serious piglet death etc..Disease
Reason variation is mainly that large intestine inner wall oedema mitigates, and mucosal inflammation aggravates, mucous membrane superficial necrosis, and it is false to form mucus fibrin
Film, appearance are in wheat bran sample or bean curd slag specimen, peel off the rotten to the corn face that pseudomembrane then exposes superficial.Through clinical symptoms, pathological change and reality
Room diagnosis is tested, swine dysentery is diagnosed as.
Chinese medicine composition after the sieving of Example 5 is gavaged according to the dosage of 40 grams/, is used in conjunction 7 days, disease after 5 days
Shape disappears substantially, has no in 7 days repeatedly, and disease must be cured, and restores normal after 10 days.
Effect example 5
Zou farm of Heze city of Shandong province raises 16 batches of 817 broiler chicken, and proventriculitis incidence is high, 7 times especially last, every batch of
In 14-18 age in days chicken infectious provenculitis occurs for the broiler chicken of raising.In May, 2015 is randomly selected newly into 817 broiler chicken, 20000 plumage
600 are divided into two groups, and test group is prevented using Chinese medicine composition of the invention, and another group is control group, press during raising
More solito raising carries out.According to nearest 7 batches of chicken occurrence regularities, test group takes the Chinese medicine composition of case study on implementation 3 in 7 ages in days, presses
It is used according to the dosage of 0.25g/ only, boiling, spice, free choice feeding are used in conjunction 5 days the medical fluid dregs of a decoction simultaneously.Control group chicken when 16 age in days
Occurs death suddenly, disease incidence is about 25%, and morbidity amounted to dead 13 in 5 days, the death rate 4.33%；Jumpbogroup chicken lassitude,
Feed intake and amount of drinking water decline, growth retardation, diarrhea etc., pathological change is mainly glandular stomach, glandular stomach swelling, mucosa hemorrhage, nipple
It is recessed, muscular stomach glandular stomach intersection is thinning etc., 16 age in days of test group is to having no dead during 21 ages in days, the speed of growth is normal, feeding
Amount, amount of drinking water, excrement etc. are normal.Control group takes the Chinese medicine composition of embodiment 3 after falling ill 5 days, according to the dosage of 0.5g/ only
It uses, boiling, the medical fluid dregs of a decoction while spice concentrate first use daily, whole feed intake, amount of drinking water base after being used in conjunction 5 days, 5 days
This recovery is normal, excrement basic forming, during which after dead 3,7 days, has no Relapse rate, disease recovery from illness, items refer to after 10 days
Mark restores normal.It can be seen that the traditional chinese medicine composition of the invention prevents and treats proventriculitis significant effect.
Above-described embodiment is the preferred embodiment of the present invention, but embodiments of the present invention are not by above-described embodiment
Limitation, it is other any without departing from the substitute mode that should be equivalent is changed made by the present invention, it is included in guarantor of the invention
Within the scope of shield.
Claims (3)
1. a kind of Chinese medicine composition for treating and preventing livestock and poultry and fur-bearing animal gastroenteritis, which is characterized in that in parts by weight, institute
It states composition to be made of following bulk drugs: 5-25 parts of Divine Comedy, 10-35 parts of malt, 10-35 parts of dried orange peel, 5-25 parts of Fructus Aurantii, Radix Codonopsis
10-30 parts, 5-25 parts of Radix Astragali, 10-35 parts of dark plum, 10-40 parts of myrobalan, 10-40 parts of alum, 10-40 parts of the coptis, garden burnet 10-35
Part, 10-45 parts of Fructus Forsythiae, 10-45 parts of honeysuckle, 10-40 parts of Radix Glycyrrhizae.
2. treating and preventing the Chinese medicine composition of livestock and poultry and fur-bearing animal gastroenteritis as described in claim 1, which is characterized in that
The raw material medicines in portions by weight composition is as follows: 10-15 parts of Divine Comedy, 15-25 parts of malt, 15-22 parts of dried orange peel, 8-15 parts of Fructus Aurantii, Radix Codonopsis
15-25 parts, 10-15 parts of Radix Astragali, 16-25 parts of dark plum, 18-30 parts of myrobalan, 20-30 parts of alum, 20-30 parts of the coptis, garden burnet 16-28
Part, 25-36 parts of Fructus Forsythiae, 25-36 parts of honeysuckle, 20-30 parts of Radix Glycyrrhizae.
3. treating and preventing the Chinese medicine composition of livestock and poultry and fur-bearing animal gastroenteritis as claimed in claim 2, which is characterized in that
Raw material medicines in portions by weight composition is as follows: 12.5 parts of Divine Comedy, 20 parts of malt, 18.5 parts of dried orange peel, 11.5 parts of Fructus Aurantii, 20 parts of Radix Codonopsis,
12.5 parts of Radix Astragali, 20.5 parts of dark plum, 24 parts of myrobalan, 25 parts of alum, 25 parts of the coptis, 22 parts of garden burnet, 30.5 parts of Fructus Forsythiae, honeysuckle
30.5 parts, 25 parts of Radix Glycyrrhizae.
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| 鸡大肠杆菌病的诊断;杨凤兰 等;《河南畜牧兽医》;20020215;第23卷(第2期);第28页 * |
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