CN105250809A - Traditional Chinese medicine composition for treating dermatomyositis - Google Patents
Traditional Chinese medicine composition for treating dermatomyositis Download PDFInfo
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- CN105250809A CN105250809A CN201510681481.1A CN201510681481A CN105250809A CN 105250809 A CN105250809 A CN 105250809A CN 201510681481 A CN201510681481 A CN 201510681481A CN 105250809 A CN105250809 A CN 105250809A
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Abstract
The invention relates to traditional Chinese medicine composition for treating dermatomyositis. The traditional Chinese medicine composition comprises raw materials of traditional Chinese medicines in parts by weight as follows: 5-25 parts of donkey-hide gelatin, 5-20 parts of acanthopanax root bark, 10-30 parts of Japanese cayratia herbs, 5-20 parts of long-nosed pit viper, 5-25 parts of dodder seeds, 5-20 parts of duckweed, 2-8 parts of garden balsam, 5-25 parts of desertliving cistanche, 5-20 parts of flatstem milkvetch seeds, 10-30 parts of prepared rehmannia roots, 5-25 parts of wooly datchmanspipe herbs, 10-30 parts of coix seeds, 5-20 parts of morinda roots, 5-20 parts of herbs of variegate ladyslipper, 5-25 parts of glassy ganoderma, 5-20 parts of burdock, 5-20 parts of ephedra herbs, 10-30 parts of European verbena herbs, 5-20 parts of loose knots, 5-20 parts of siegesbeckia herbs and 5-15 parts of liquorice roots. The traditional Chinese medicine composition has effects of tonifying the liver and the kidney, nourishing the spleen, benefiting qi, dispelling the wind, removing dampness, clearing heat, removing toxins, promoting blood circulation, removing meridian obstruction, relaxing tendons and removing pain or numbness, has the significant effect on the dermatomyositis and has the reliable action.
Description
Technical field
The present invention relates to a kind of pharmaceutical product not determining structure of traditional herbal medicines, especially a kind of Chinese medicine composition for the treatment of dermatomyositis.
Background technology
Dermatomyositis is that one mainly involves striped muscle, the nonsuppurative inflammation pathological changes based on lymphocytic infiltration, can with or damage without various skin.Dermatomyositis can betide any age, and onset peak child was at 5 ~ 15 years old, and be grown up at 30 ~ 50 years old, women is slightly more than male.Clinically with symmetry gridle muscle, cervical muscle and pharynx myasthenia for feature, often involve multiple internal organs, the tumor that also can occur together and other connective tissue diseases.Main clinical manifestation: usually hiddenly attack onset, is slowly in progress within several weeks, several months, several years., there is serious myasthenia in only a few patients acuity onset, even rhabdomyolysis, myoglobinuria and renal failure within a few days.Patient can have stiff, weak, inappetence in morning, loses weight, generate heat (middle low heat, even high heat), arthralgia, and small number of patients has Raynaud phenomenon.Dermatomyositis morbidity may be relevant with the factor such as tumor, infection, medicine, endocrine, metabolism.The development in chronic progressive external of dermatomyositis major part, favourable prognosis, can recover normal in 2 ~ 3 years, small part acute attack person, often because accompanying infection is dead, accompanying tumors person.Current doctor trained in Western medicine many employings hormone and immunosuppressant treatment, side effect is comparatively large, and curative effect is very not remarkable again.
Motherland's medical science thinks that dermatomyositis belongs to the category such as " BI-syndrome involved the muscle ", " flaccidity ", " asthenia " of the traditional Chinese medical science.Its pathogenesis is mainly deficiency of spleen and stomach, no resource of generating and transforming QI and blood, weakened body resistancely can not drive heresy, the damp and hot network accumulateing resistance skin of wind and cold, and then affect Liver and kidney spleen, causes the internal organs yin collaterals stasis of blood stagnant, qi-blood disharmony, limbs skin muscle arteries and veins lose foster caused by.
According to theory of Chinese medical science, for the pathogeny of dermatomyositis, adopt the liver and the kidney tonifying, invigorating the spleen and replenishing QI, expelling wind and removing dampness, heat-clearing and toxic substances removing, promoting blood circulation to remove obstruction in the collateral
,the method for the treatment of of arthralgia relieving by relaxing muscles and tendons, carries out dialectical composition of prescription, to reach the object for the treatment of both the principal and secondary aspects of a disease.
Summary of the invention
In order to overcome prior art integrative therapy dermatomyositis, to there is side effect comparatively large, and curative effect is very significant not enough again, the invention provides a kind of prepare easy, cost is low, evident in efficacy, the Chinese medicine composition for the treatment of dermatomyositis that has no side effect.
The technical solution adopted for the present invention to solve the technical problems is: a kind of Chinese medicine composition for the treatment of dermatomyositis, it is characterized in that: its raw material of Chinese medicine and weight are: Colla Corii Asini 5-25 part, Cortex Acanthopancis 5-20 part, Herba Ipomoeae Cairicae 10-30 part, Agkistrodon 5-20 part, Semen Cuscutae 5-25 part, Herba Spirodelae 5-20 part, Flos Impatientis 2-8 part, Herba Cistanches 5-25 part, Semen Astragali Complanati 5-20 part, Radix Rehmanniae Preparata 10-30 part, Herba Aristolochiae Mollissimae 5-25 part, Semen Coicis 10-30 part, Radix Morindae Officinalis 5-20 part, Herba Cyperipedii Margaritacei 5-20 part, Ganoderma 5-25 part, Fructus Arctii 5-20 part, Herba Ephedrae 5-20 part, horsewhip 10-30 part, Lignum Pini Nodi 5-20 part, Herba Siegesbeckiae 5-20 part, Radix Glycyrrhizae 5-15 part.
The preferred technical solution of the present invention is: a kind of Chinese medicine composition for the treatment of dermatomyositis, is characterized in that: its raw material of Chinese medicine and weight are: 15 parts, Colla Corii Asini, Cortex Acanthopancis 10 parts, Herba Ipomoeae Cairicae 20 parts, Agkistrodon 10 parts, Semen Cuscutae 15 parts, 10 parts, Herba Spirodelae, Flos Impatientis 5 parts, Herba Cistanches 15 parts, Semen Astragali Complanati 10 parts, Radix Rehmanniae Preparata 20 parts, Herba Aristolochiae Mollissimae 15 parts, Semen Coicis 20 parts, Radix Morindae Officinalis 10 parts, Herba Cyperipedii Margaritacei 12 parts, Ganoderma 15 parts, Fructus Arctii 10 parts, 10 parts, Herba Ephedrae, Herba Verbenae 20 parts, Lignum Pini Nodi 10 parts, Herba Siegesbeckiae 10 parts, 10 parts, Radix Glycyrrhizae.
Chinese medicine composition of the present invention is under Traditional Chinese medical theory and clinical experience instruct, selected medicament composing prescription.In Chinese medicine composition of the present invention: Colla Corii Asini has nourshing Yin and drynsessmoistening prescription, blood yiqi, arresting bleeding and miscarriage prevention effect; Cortex Acanthopancis has effect of wind-damp dispelling, invigorating the liver and kidney, bone and muscle strengthening; Herba Ipomoeae Cairicae has expelling wind and removing dampness
,effect of removing blood stasis to reduce swelling; Agkistrodon have dispel the wind, effect of dredging collateral, relieving convulsion; Semen Cuscutae has effect of the kidney invigorating and essence nourishing, nourishing the liver spleen invigorating; Herba Spirodelae has that relieving the exterior syndrome by diaphoresis, rash are antipruritic, effect of inducing diuresis to remove edema, heat-clearing and toxic substances removing; Flos Impatientis has effect of expelling wind and removing dampness, promoting blood circulation and stopping pain, removing toxic substances parasite killing; Herba Cistanches has effect of kidney-replenishing, benefiting essence-blood, loosening bowel to relieve constipation; Semen Astragali Complanati has effect of the liver and the kidney tonifying, improving eyesight controlling nocturnal emission with astringent drugs; Effect that Radix Rehmanniae Preparata has nourishing YIN and supplementing blood, beneficial essence fills out marrow; Herba Aristolochiae Mollissimae has expelling wind and removing dampness
,promoting blood circulation to remove obstruction in the collateral
,effect of pain relieving; Semen Coicis has inducing diuresis to remove edema, spleen invigorating is dried, effect of arthralgia relieving by relaxing muscles and tendons, clearing away heat and discharging pus; Radix Morindae Officinalis has effect of reinforcing the kidney and supporting YANG, bone and muscle strengthening, expelling wind and removing dampness; Herba Cyperipedii Margaritacei has effect of the liver and the kidney tonifying, improving eyesight diuresis; Ganoderma has effect of replenishing QI and blood, tranquilizing mind, strengthening the spleen and stomach; Fructus Arctii has effect of dispelling wind and heat pathogens, lung qi dispersing rash, sore-throat relieving eliminating stagnation, removing toxic substances and promoting subsidence of swelling; Herba Ephedrae has effect of relieving the exterior syndrome by diaphoresis, depressed lung-energy dispersing, inducing diuresis to remove edema; Herba Verbenae has effect of heat-clearing and toxic substances removing, promoting blood circulation to remove blood stasis, inducing diuresis to remove edema; Lignum Pini Nodi has dispeiling pathogenic wind and removing dampness
,channels sootheing and network vessel quickening
,effect of promoting blood circulation and stopping pain; Herba Siegesbeckiae has effect of expelling wind and removing dampness, dredge the meridian passage, heat-clearing and toxic substances removing; Radix Glycyrrhizae has effect of invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, coordinating the actions of various ingredients in a prescription.The selected medicament composing prescription of the present invention, its drug component, through dialectical compatibility, helps using mutually assistant, plays the liver and the kidney tonifying, invigorating the spleen and replenishing QI, expelling wind and removing dampness, heat-clearing and toxic substances removing, promoting blood circulation to remove obstruction in the collateral altogether
,effect of arthralgia relieving by relaxing muscles and tendons, reaches treating both the principal and secondary aspects of a disease to the treatment of dermatomyositis.
The component of the present composition all adopts natural raw material of Chinese medicine, and its preparation is easy, medicine source is wide, cost is low.The present invention follows the prescriptions principle of the traditional Chinese medical science, and various component drug adopts the use that is decocted in water for oral dose.Through clinical practice checking, it is reliably evident in efficacy, mild in medicine property and, do not occur toxic and side effects, effective percentage reaches 95%, cure rate 75%.
Detailed description of the invention
Below in conjunction with embodiment, the invention will be further described.
Embodiment 1
Treat a Chinese medicine composition for dermatomyositis, its raw material of Chinese medicine and weight proportion are: Colla Corii Asini (melt punching) 15g, Cortex Acanthopancis 10g, Herba Ipomoeae Cairicae 20g, Agkistrodon 10g, Semen Cuscutae 15g, Herba Spirodelae 10g, Flos Impatientis 5g, Herba Cistanches 15g, Semen Astragali Complanati 10g, Radix Rehmanniae Preparata 20g, Herba Aristolochiae Mollissimae 15g, Semen Coicis 20g, Radix Morindae Officinalis 10g, Herba Cyperipedii Margaritacei 12g, Ganoderma 15g, Fructus Arctii 10g, Herba Ephedrae 10g, Herba Verbenae 20g, Lignum Pini Nodi 10g, Herba Siegesbeckiae 10g, Radix Glycyrrhizae 10g.
Embodiment 2
Treat a Chinese medicine composition for dermatomyositis, its raw material of Chinese medicine and weight proportion are: Colla Corii Asini (melt punching) 5g, Cortex Acanthopancis 15g, Herba Ipomoeae Cairicae 10g, Agkistrodon 20g, Semen Cuscutae 5g, Herba Spirodelae 15g, Flos Impatientis 4g, Herba Cistanches 20g, Semen Astragali Complanati 12g, Radix Rehmanniae Preparata 25g, Herba Aristolochiae Mollissimae 5g, Semen Coicis 30g, Radix Morindae Officinalis 12g, Herba Cyperipedii Margaritacei 20g, Ganoderma 5g, Fructus Arctii 15g, Herba Ephedrae 5g, Herba Verbenae 25g, Lignum Pini Nodi 12g, Herba Siegesbeckiae 20g, Radix Glycyrrhizae 15g.
Embodiment 3
Treat a Chinese medicine composition for dermatomyositis, its raw material of Chinese medicine and weight proportion are: Colla Corii Asini (melt punching) 20g, Cortex Acanthopancis 5g, Herba Ipomoeae Cairicae 25g, Agkistrodon 12g, Semen Cuscutae 20g, Herba Spirodelae 5g, Flos Impatientis 8g, Herba Cistanches 10g, Semen Astragali Complanati 15g, Radix Rehmanniae Preparata 30g, Herba Aristolochiae Mollissimae 10g, Semen Coicis 25g, Radix Morindae Officinalis 5g, Herba Cyperipedii Margaritacei 15g, Ganoderma 10g, Fructus Arctii 20g, Herba Ephedrae 12g, Herba Verbenae 15g, Lignum Pini Nodi 20g, Herba Siegesbeckiae 5g, Radix Glycyrrhizae 12g.
Embodiment 4
Treat a Chinese medicine composition for dermatomyositis, its raw material of Chinese medicine and weight proportion are: Colla Corii Asini (melt punching) 10g, Cortex Acanthopancis 20g, Herba Ipomoeae Cairicae 15g, Agkistrodon 5g, Semen Cuscutae 25g, Herba Spirodelae 12g, Flos Impatientis 6g, Herba Cistanches 5g, Semen Astragali Complanati 20g, Radix Rehmanniae Preparata 10g, Herba Aristolochiae Mollissimae 25g, Semen Coicis 15g, Radix Morindae Officinalis 20g, Herba Cyperipedii Margaritacei 10g, Ganoderma 25g, Fructus Arctii 5g, Herba Ephedrae 20g, Herba Verbenae 10g, Lignum Pini Nodi 15g, Herba Siegesbeckiae 12g, Radix Glycyrrhizae 5g.
Embodiment 5
Treat a Chinese medicine composition for dermatomyositis, its raw material of Chinese medicine and weight proportion are: Colla Corii Asini (melt punching) 25g, Cortex Acanthopancis 12g, Herba Ipomoeae Cairicae 30g, Agkistrodon 15g, Semen Cuscutae 10g, Herba Spirodelae 20g, Flos Impatientis 2g, Herba Cistanches 25g, Semen Astragali Complanati 5g, Radix Rehmanniae Preparata 15g, Herba Aristolochiae Mollissimae 20g, Semen Coicis 10g, Radix Morindae Officinalis 15g, Herba Cyperipedii Margaritacei 5g, Ganoderma 20g, Fructus Arctii 12g, Herba Ephedrae 15g, Herba Verbenae 30g, Lignum Pini Nodi 5g, Herba Siegesbeckiae 15g, Radix Glycyrrhizae 8g.
Other components decocting method all routinely of Chinese medicine composition in the embodiment of the present invention except Colla Corii Asini (melt punching) produces medicament.Concrete grammar is as follows: the raw material of Chinese medicine of prescription is put into container, adds cold water and covers powder, soaks 15 ~ 20 minutes, then adds water and do not have powder about 6 centimetres, carries out first time to decoct, and adopts intense fire to decoct, with slow fire boiling 20 ~ 30 minutes after boiling at a simmer; Second time decocts, and adds water and does not have powder about 4 centimetres, decocts 15 ~ 20 minutes after water boils.Decoct extracting juice twice, merge.
The present invention, with a kind of Chinese medicine composition for the treatment of dermatomyositis given by embodiment 1, does clinical efficacy and is summarized as follows:
One, general data: this Chinese medicine composition is applied to clinical observation case 60 example, man 21 example, female 39 example, 30 ~ 55 years old age.
Two, diagnosis basis:
1, with limb muscle weakness, muscular soreness, munbness is feature.From the beginning of can hurriedly occur, continue, soft difficulty is held, and the soft difficulty of arm is lifted, and the soft difficulty of foot is carried out.Very then involve pharynx, neck and chest muscle.Can be there is diplopia, stravismus in severe patient, hoarseness, swallows and dyspnea;
2, be more common in 20 ~ 40 years old women, before disease, diseases caused by exogenous pathogenic factor history can be had, or arthrosis and tumor history;
3, extremity near-end muscular strength obviously weakens, and myalgia matter is hard, and disease can have amyotrophy for a long time;
4, acute onset total white blood cells increases, and erythrocyte sedimentation rate speeds, and serum creatine phosphokinase (CPK) Chang Xianzhu increases, and aldolase, lactic acid dehydrogenase, millet straw, glutamate pyruvate transaminase and protein electrophoresis α, beta Globulin increased in active stage;
5, electromyogram: electronegative potential, shortwave width, polyphasic wave; Fibrillation potential, positive spike, inserts potential prolongation;
6, tissue pathology checking shows that muscle fiber has inflammatory to change, and muscle fiber is broken, and hyalinosis, unclear transverse striation of muscle fiber, has edema and inflammatory cell infiltration in interstitial.
Three, usage and dosage: during clinical practice, potion on the one, decocting twice extracting juice is about 400ml, point morning, late twice empty stomach decoction being taken warmly.It within ten days, is a course for the treatment of.Treatments period is avoided cold and uncooked food the thing of pungent stimulation.
Four, criterion of therapeutical effect:
1, cure: symptom, sign disappear substantially, and lab testing is normal;
2, effective: symptom alleviates, sign is improved, and lab testing takes a turn for the better;
3, invalid: symptom, sign, lab testing are unchanged.
Five, therapeutic effect: in this clinical observation case, takes medicine 2-5 the course for the treatment of, and recovery from illness 45 example, follows up a case by regular visits to and have no recurrence; Effective 12 examples, invalid 3 examples.There is not toxic and side effects in treatments period.
Six, model case:
Case 1:
Poplar, man, 39 years old.There is Dual-eyelid surrounding skin edema in patient, color of the leather is purplish red, but superficial before 1 month.Be irritated at certain hospital diagnosis, fail to respond to any medical treatment through application desensitizer.Find that muscle is miserable in the recent period gradually, myasthenia of limbs, dysphoria with feverish sensation in the chest palms and soles.Two handss are pale or purplish red, cold type of pain.Around Dual-eyelid, swelling increases the weight of, and has and expand trend towards periphery.Hospital is diagnosed as dermatomyositis.Improvement is had no in hospital through multi-medicament treatment.Take 2 courses for the treatment of of medicament prepared by Chinese medicine composition of the present invention, both hands color of the leather is normal, and around Dual-eyelid, color of the leather is thin out, and edema, cold type of pain disappear; Continue to take 3 courses for the treatment of, all symptoms disappear completely, recover.
Case 2:
Zhang, female, 42 years old.Before 2 months there is red rash in cervical vertebra and head, and cerise macule appears in face, upper eyelid then, and limb muscle ache is unable, with extremities joint pain, and right knee joint swelling, and have heating paresthesia, be dermatomyositis through hospital diagnosis.Use prednisone oral medication, the state of an illness is taken a turn for the better.Take 2 courses for the treatment of of medicament prepared by Chinese medicine composition of the present invention, cervical vertebra Schultz-Charlton, facial macule also alleviates; Continue to take 2 courses for the treatment of, transference cure, Myodynamia recovery, half a year is without recurrence so far.
Claims (2)
1. treat the Chinese medicine composition of dermatomyositis for one kind, it is characterized in that: its raw material of Chinese medicine and weight are: Colla Corii Asini 5-25 part, Cortex Acanthopancis 5-20 part, Herba Ipomoeae Cairicae 10-30 part, Agkistrodon 5-20 part, Semen Cuscutae 5-25 part, Herba Spirodelae 5-20 part, Flos Impatientis 2-8 part, Herba Cistanches 5-25 part, Semen Astragali Complanati 5-20 part, Radix Rehmanniae Preparata 10-30 part, Herba Aristolochiae Mollissimae 5-25 part, Semen Coicis 10-30 part, Radix Morindae Officinalis 5-20 part, Herba Cyperipedii Margaritacei 5-20 part, Ganoderma 5-25 part, Fructus Arctii 5-20 part, Herba Ephedrae 5-20 part, horsewhip 10-30 part, Lignum Pini Nodi 5-20 part, Herba Siegesbeckiae 5-20 part, Radix Glycyrrhizae 5-15 part.
2. a kind of Chinese medicine composition for the treatment of dermatomyositis according to claim 1, is characterized in that: its raw material of Chinese medicine and weight are: 15 parts, Colla Corii Asini, Cortex Acanthopancis 10 parts, Herba Ipomoeae Cairicae 20 parts, Agkistrodon 10 parts, Semen Cuscutae 15 parts, 10 parts, Herba Spirodelae, Flos Impatientis 5 parts, Herba Cistanches 15 parts, Semen Astragali Complanati 10 parts, Radix Rehmanniae Preparata 20 parts, Herba Aristolochiae Mollissimae 15 parts, Semen Coicis 20 parts, Radix Morindae Officinalis 10 parts, Herba Cyperipedii Margaritacei 12 parts, Ganoderma 15 parts, Fructus Arctii 10 parts, 10 parts, Herba Ephedrae, Herba Verbenae 20 parts, Lignum Pini Nodi 10 parts, Herba Siegesbeckiae 10 parts, 10 parts, Radix Glycyrrhizae.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106074976A (en) * | 2016-07-26 | 2016-11-09 | 林红丽 | A kind of Chinese medicine composition treating dermatomyositis |
| CN106109788A (en) * | 2016-07-26 | 2016-11-16 | 林红丽 | A kind of Chinese medicine composition treating dermatomyositis |
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2015
- 2015-10-21 CN CN201510681481.1A patent/CN105250809A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106074976A (en) * | 2016-07-26 | 2016-11-09 | 林红丽 | A kind of Chinese medicine composition treating dermatomyositis |
| CN106109788A (en) * | 2016-07-26 | 2016-11-16 | 林红丽 | A kind of Chinese medicine composition treating dermatomyositis |
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Application publication date: 20160120 |