CN103520498A

CN103520498A - Chinese medicinal composition for treating cerebral arteriosclerosis neurasthenia syndrome

Info

Publication number: CN103520498A
Application number: CN201310491607.XA
Authority: CN
Inventors: 李宪锋; 艾洪艳
Original assignee: Individual
Current assignee: Individual
Priority date: 2013-10-11
Filing date: 2013-10-11
Publication date: 2014-01-22
Anticipated expiration: 2033-10-11
Also published as: CN103520498B

Abstract

The invention discloses a Chinese medicinal composition for treating cerebral arteriosclerosis neurasthenia syndrome. The traditional Chinese medicine doctors think that the syndrome is caused by the deficiency of vitality, yin-fluid and blood, and moistening and nourishing in muscle and vessel or heart and kidney, emptiness of brain, dysfunction of the spleen in transport and the like. According to the Chinese medicinal composition, the Chinese medicines including conic gymnadenia tuber, swallowwort herb, hemipilia, medicinal indianmulberry roots, harbenaria herbs, curious kadsura fruits, rhizoma tupistrae chinensis, rust-brown crotalaria, sago leaf, African marigold, Indian scutellaria and rhodobryum, which have the functions of replenishing qi and invigorating the spleen, tonifying the liver and kidney, invigorating the circulation of the tires and dredging collaterals, are decocted with water to prepare decoction; the clinical test shows that the total effective rate is up to 95.0 percent, and the Chinese medicinal composition is obviously superior to that of a control group; moreover, the Chinese medicinal composition is low in side effects and the adverse reaction is avoided after patients orally take the medicines.

Description

A kind of Chinese medicine composition for the treatment of cerebral arteriosclerosis neurasthenia syndrome

Technical field

The present invention relates to a kind of Chinese medicine composition, relate in particular to a kind of Chinese medicine composition for the treatment of cerebral arteriosclerosis neurasthenia syndrome.

Background technology

Cerebral arteriosclerosis, can cause cerebral ischemia, brain atrophy, or causes rupture of blood vessel in brain hemorrhage.The commitment of cerebral arteriosclerosis can cause neurasthenia, and emotion is abnormal, and judgement is low.When reaching middle and late stage, cerebral arteriosclerosis can occur that gait is stiff or walking is unstable, dementia, epileptic convulsion, apoplexy.Cerebral arteriosclerosis neurasthenia syndrome is because cerebral arteriosclerosis causes neurocyte degeneration, necrosis, glial cells hyperplasia, finally produces disordered brain function syndrome, clinical manifestation mainly contains giddy, headache, insomnia, forgetful, difficult concentrating, anxiety, anxiety, agitation, tired, work efficiency reduces, fearness sound, tinnitus, general malaise and lethargy etc.Can be with vegetative nerve and sexual disorder.At present, treat this sick doctor trained in Western medicine and also lack more satisfactory method, applicant, through clinical trial for many years, utilizes this disease for the treatment of by Chinese herbs to obtain good effect.

Summary of the invention

The object of this invention is to provide a kind of Chinese medicine composition for the treatment of cerebral arteriosclerosis neurasthenia syndrome.Primary disease belongs to Chinese medicine " dizzy ", " headache " category, and the traditional Chinese medical science thinks that primary disease is that first deficiency of vital energy declines, and cloudy anemia is damaged, and muscle arteries and veins loses it and moistens fosterly, or heart deficiency of the kidney damages, and brain is hollow, due to the reasons such as dysfunction of the spleen in transportation.Primary disease is the card of vital QI being weakened and pathogen being violent, and controlling should giving consideration to both the incidental and fundamental, and take replenishing QI to invigorate the spleen, liver and kidney tonifying, the tired dredging collateral of invigorating blood circulation is the rule for the treatment of.

The object of the invention is to be achieved through the following technical solutions, the Chinese medicine composition of this treatment cerebral arteriosclerosis neurasthenia syndrome is made by the Chinese medicine of following weight portion: Rhizoma Gymnadeniae 9-15 part, Radix Tylophorae arenicolae 15-25 part, leaf Miscanthus sacchariflorus (Maxim) Benth et Hook f 20-25 part, Radix Morindae Officinalis 5-15 part, Herba Habenariae rhodochellae 10-20 part, Fructus Kadsurae heteroclitae 10-15 part, Rhizoma Tupistrae Chinensis 8-16 part, Herba Crotalariae Ferrugineae 35-45 part, Folium Cycadis Revolute 15-25 part, Flos Tagetis Erectae 5-15 part, Herba Scutellariae indicae 12-20 part, Rhodobryum giganteum(Hook.) Par. 10-20 part.

Preferred: 12 parts of Rhizoma Gymnadeniaes, 20 parts of Radix Tylophorae arenicolaes, a leaf obtain 23 parts, 10 parts of Radix Morindae Officinaliss, 15 parts of Herba Habenariae rhodochellaes, 12 parts of Fructus Kadsurae heteroclitaes, 13 parts of Rhizoma Tupistrae Chinensis, 40 parts of Herba Crotalariae Ferrugineaes, 20 parts of Folium Cycadis Revolutes, 10 parts of Flos Tagetis Erectaes, 15 parts of Herba Scutellariae indicae, 16 parts of Rhodobryum giganteum(Hook.) Par.s.

Preparation method is made decoction by above-mentioned Chinese medicine decocting.

In side: Rhizoma Gymnadeniae strengthening by means of tonics, spleen reinforcing lung moistening, calms the nerves relieving convulsion, QI invigorating pain relieving; Radix Tylophorae arenicolae kidney and spleen invigorating, removing toxic substances; One leaf obtains relaxing muscles and tendons to promote blood circulation, tonifying speen and tonifying kidney; Radix Morindae Officinalis, Herba Habenariae rhodochellae kidney-replenishing, wind-damp dispelling; The kidney invigorating of Fructus Kadsurae heteroclitae heart tonifying, eliminating phlegm and stopping cough; Rhizoma Tupistrae Chinensis nourishing yin and promoting blood circulation; Herba Crotalariae Ferrugineae invigorating the spleen and replenishing QI, diuretic antiinflammatory; Folium Cycadis Revolute vital energy regualting and blood circulation-promoting suppressing the hyperactive liver; Flos Tagetis Erectae is enriched blood and is stimulated the menstrual flow, promoting tissue regeneration by removing blood stasis; Herba Scutellariae indicae dispels the wind, invigorates blood circulation, and removing toxic substances, pain relieving; Rhodobryum giganteum(Hook.) Par. tranquillizing and allaying excitement, improving eyesight clears away heart-fire.

Clinical data

1. physical data is originally organized 120 examples and is out-patient, by table of random number, case is equally divided into treatment group and matched group at random.Treatment group 60 examples, male 35 examples, female's 25 examples, 43～70 years old age, average 55.1 years old, the course of disease 2 months～9 years.Matched group 60 examples, male 37 examples, female's 23 examples, 45～73 years old age, average 56.3 years old, the course of disease 2 months～10 years.Two groups of patient's comparisons aspect sex, age, the course of disease, and no significant difference (P > 0.05), there is comparability.

2. diagnostic criteria is with reference to " the cerebral arteriosclerosis diagnostic criteria " of the academic meeting revision of the neural psychiatric department in the 3rd, the whole nation in 1981, armarium situation in conjunction with my institute, formulate following diagnostic criteria: (1) has neurasthenia's disease group's clinical manifestation, as dizzy, headache, one's ears rang and spots danced before one's eyes, fatigue and weakness, forgetful agitation, bradyphrenia, sleep disorder; (2) more than ocular fundus arteriosclerosis II level; (3) serum cholesterol and triglyceride increase; (4) transcranial doppler (TCD) shows cerebral arteriosclerosis; (5) in conjunction with CT scan, except can cause other disease of brain of similar clinical manifestation.

3. Therapeutic Method treatment group patient takes Chinese medicine composition of the present invention, take Rhizoma Gymnadeniae 12g, Radix Tylophorae arenicolae 20g, a leaf obtains 23g, Radix Morindae Officinalis 10g, Herba Habenariae rhodochellae 15g, Fructus Kadsurae heteroclitae 12g, Rhizoma Tupistrae Chinensis 13g, Herba Crotalariae Ferrugineae 40g, Folium Cycadis Revolute 20g, Flos Tagetis Erectae 10g, Herba Scutellariae indicae 15g, Rhodobryum giganteum(Hook.) Par. 16g, decocting becomes decoction, every day potion, dividing and sooner or later take for 2 times, 14th is 1 course for the treatment of; Matched group oral vitamin E0.1g, every day 3 times, nimodipine 20mg, every day 3 times, piracetam 0.8g, every day 3 times; Two groups all serve on 4 courses for the treatment of.

4. criterion of therapeutical effect is by the standard rating curative effect in " guideline of clinical investigations of new Chinese medicine treatment cerebral arteriosclerosis ".Cure: primary symptom disappears, the main Index for examination result such as TCD, blood fat, optical fundus is normal; Effective: primary symptom integration reduces more than 70%, and TCD obviously improves, and blood fat obviously declines; Effective: primary symptom integration reduces 36%-69%, and TCD has some improvement, rate and blood-lipid decreased; Invalid: not reach above-mentioned effective standard.

5. curative effect comparison after 4 courses for the treatment of of two groups of therapeutic effect treatment, treatment group 60 examples, wherein cure 35 examples (58.3%); Effective 15 examples (25.5%), effective 7 examples (11.7%), invalid 3 examples (5.0%), total effective rate 95.0%; Matched group 60 examples, wherein cure 18 examples (30.0%); Effective 20 examples (33.3%), effective 11 examples (18.3%), invalid 11 examples (18.3%), total effective rate 81.7%.Two groups of comparisons, treatment group cure rate, total effective rate are obviously better than matched group, have comparability.P<0.05。

The specific embodiment

Embodiment mono-: take Rhizoma Gymnadeniae 12g, Radix Tylophorae arenicolae 20g, a leaf obtains 23g, Radix Morindae Officinalis 10g, Herba Habenariae rhodochellae 15g, Fructus Kadsurae heteroclitae 12g, Rhizoma Tupistrae Chinensis 13g, Herba Crotalariae Ferrugineae 40g, Folium Cycadis Revolute 20g, Flos Tagetis Erectae 10g, Herba Scutellariae indicae 15g, Rhodobryum giganteum(Hook.) Par. 16g, and above-mentioned Chinese medicine decocting is become to decoction.

Embodiment bis-: take Rhizoma Gymnadeniae 15g, Radix Tylophorae arenicolae 25g, a leaf obtains 20g, Radix Morindae Officinalis 15g, Herba Habenariae rhodochellae 10g, Fructus Kadsurae heteroclitae 15g, Rhizoma Tupistrae Chinensis 8g, Herba Crotalariae Ferrugineae 45g, Folium Cycadis Revolute 25g, Flos Tagetis Erectae 5g, Herba Scutellariae indicae 20g, Rhodobryum giganteum(Hook.) Par. 10g, and above-mentioned Chinese medicine decocting is become to decoction.

Embodiment tri-: take Rhizoma Gymnadeniae 9g, Radix Tylophorae arenicolae 15g, a leaf obtains 25g, Radix Morindae Officinalis 5g, Herba Habenariae rhodochellae 20g, Fructus Kadsurae heteroclitae 10g, Rhizoma Tupistrae Chinensis 16g, Herba Crotalariae Ferrugineae 35g, Folium Cycadis Revolute 15g, Flos Tagetis Erectae 15g, Herba Scutellariae indicae 12g, Rhodobryum giganteum(Hook.) Par. 20g, and above-mentioned Chinese medicine decocting is become to decoction.

Claims

1. treat a Chinese medicine composition for cerebral arteriosclerosis neurasthenia syndrome, it is characterized in that this Chinese medicine composition made by the Chinese medicine of following weight portion: Rhizoma Gymnadeniae 9-15 part, Radix Tylophorae arenicolae 15-25 part, a leaf obtain 20-25 part, Radix Morindae Officinalis 5-15 part, Herba Habenariae rhodochellae 10-20 part, Fructus Kadsurae heteroclitae 10-15 part, Rhizoma Tupistrae Chinensis 8-16 part, Herba Crotalariae Ferrugineae 35-45 part, Folium Cycadis Revolute 15-25 part, Flos Tagetis Erectae 5-15 part, Herba Scutellariae indicae 12-20 part, Rhodobryum giganteum(Hook.) Par. 10-20 part.

2. a kind of Chinese medicine composition for the treatment of cerebral arteriosclerosis neurasthenia syndrome according to claim 1, is characterized in that this Chinese medicine composition made by the Chinese medicine of following weight portion: 12 parts of Rhizoma Gymnadeniaes, 20 parts of Radix Tylophorae arenicolaes, a leaf obtain 23 parts, 10 parts of Radix Morindae Officinaliss, 15 parts of Herba Habenariae rhodochellaes, 12 parts of Fructus Kadsurae heteroclitaes, 13 parts of Rhizoma Tupistrae Chinensis, 40 parts of Herba Crotalariae Ferrugineaes, 20 parts of Folium Cycadis Revolutes, 10 parts of Flos Tagetis Erectaes, 15 parts of Herba Scutellariae indicae, 16 parts of Rhodobryum giganteum(Hook.) Par.s.