CN105687699A

CN105687699A - Traditional Chinese medicine composition for treating vital myocarditis

Info

Publication number: CN105687699A
Application number: CN201610170723.5A
Authority: CN
Inventors: 柳晖
Original assignee: Individual
Current assignee: Individual
Priority date: 2016-03-24
Filing date: 2016-03-24
Publication date: 2016-06-22

Abstract

The invention discloses a traditional Chinese medicine composition for treating vital myocarditis. The traditional Chinese medicine composition is prepared from the following traditional Chinese medicine raw materials in parts by weight: 10 to 30 parts of herba oldenlandiae, 10 to 20 parts of shelled cedar seeds, 5 to 15 parts of radix isatidis, 10 to 20 parts of glossy privet fruit, 10 to 20 parts of cassia twig, 10 to 20 parts of evening primrose, 5 to 15 parts of dalbergia wood, 10 to 20 parts of dwarf lilyturf roots, 10 to 20 parts of common andrographis herb, 10 to 20 parts of rhizoma polygoni cuspidate, 5 to 15 parts of longan, 10 to 20 parts of herba portulacae, 10 to 20 parts of tuber fleeceflower stems, 5 to 15 parts of fructus forsythiae, 10 to 20 parts of bluish dogbane, 10 to 20 parts of radix glehniae, 5 to 15 parts of sapanwood, 10 to 20 parts of tribulus terrestris, 10 to 20 parts of polygala roots, 10 to 20 parts of cortex acanthopanacis, 10 to 20 parts of shepherd's purse and 5 to 15 parts of liquorice roots. The traditional Chinese medicine composition has the efficacies of nourishing the hearth, benefiting the spleen, promoting Qi and blood circulation, nourishing yin, promoting the secretion of saliva or body fluid, eliminating inflammation and relieving pain; the curative effect for treating the vital myocarditis is obvious; the effect is reliable.

Description

A kind of Chinese medicine composition treating viral myocarditis

Technical field

The present invention relates to the medicinal preparation not determining structure of a kind of traditional herbal medicines, especially a kind of Chinese medicine composition treating viral myocarditis。

Background technology

Viral myocarditis refers to the acute or chronic myocardial inflammation caused by various viruses。In the majority with the adult of child and less than 40 years old, the patient of about 90% is chief complaint with arrhythmia or head is shown in symptom, common cardiopalmus, uncomfortable in chest, pareordia dull pain, dizziness, the symptom such as weak, and the lighter is several asymptomatic and in subclinical process, or symptom is slight；Severe one may occur in which cardiac dilatation, cardiac insufficiency, severe arrhythmia, shock etc., even dies suddenly。At present, there is no specific treatment method clinically, adopt the symptomatic treatments such as immunosuppressant, interferon and myocardial cell nutrient more, its deficiency that existence is cured the symptoms, not the disease and side effect is big。

Viral myocarditis belongs to the sick category such as motherland's medical science palpitation with fear, palpitation with a distress feeling, the thoracic obstruction, dizziness。Many by ferritic virtual loss, the deficiency of both vital energy and Yin of the heart, so that after their early stage experiences seasonal pathogen, evil poison invasion, inside accumulates in the heart, the moon of more feeling frustrated immediately；Heresy is stayed and is not gone, and heart arteries and veins is impaired, hematogenous blockage。

According to theory of Chinese medical science, for the pathogeny of viral myocarditis, with reinforcing the heart strengthening the spleen, anti-inflammatory analgetic for the rule for the treatment of, carry out dialectical composition of prescription, to reach the purpose for the treatment of both the principal and secondary aspects of a disease。

Summary of the invention

Prior art is treated viral myocarditis exist to overcome and cure the symptoms, not the disease and the deficiency of certain side effect, the present invention provide a kind of prepare conveniently, medicine source is wide, cost is low, evident in efficacy, reliable effect, the Chinese medicine composition for the treatment of viral myocarditis that has no side effect。

The technical solution adopted for the present invention to solve the technical problems is: a kind of Chinese medicine composition treating viral myocarditis, it is characterized in that: its raw material of Chinese medicine and weight be: Herba Hedyotidis Diffusae 10-30 part, Semen Platycladi 10-20 part, Radix Isatidis 5-15 part, Fructus Ligustri Lucidi 10-20 part, Ramulus Cinnamomi 10-20 part, Radix Oenotherae erythrosepalae 10-20 part, Lignum Dalbergiae Odoriferae 5-15 part, Radix Ophiopogonis 10-20 part, Herba Andrographis 10-20 part, Rhizoma Polygoni Cuspidati 10-20 part, Arillus Longan 5-15 part, Herba Portulacae 10-20 part, Caulis Polygoni Multiflori 10-20 part, Fructus Forsythiae 5-15 part, Herba Apocyni veneti 10-20 part, Radix Glehniae 10-20 part, Lignum Sappan 5-15 part, Fructus Atriplicis Sibiricae 10-20 part, Radix Polygalae 10-20 part, Cortex Acanthopancis 10-20 part, Herba Capsellae 10-20 part, Radix Glycyrrhizae 5-15 part。

The preferred technical solution of the present invention is: a kind of Chinese medicine composition treating viral myocarditis, it is characterised in that: its raw material of Chinese medicine and weight be: Herba Hedyotidis Diffusae 20 parts, Semen Platycladi 15 parts, Radix Isatidis 10 parts, Fructus Ligustri Lucidi 15 parts, Ramulus Cinnamomi 15 parts, Radix Oenotherae erythrosepalae 15 parts, Lignum Dalbergiae Odoriferae 10 parts, Radix Ophiopogonis 15 parts, Herba Andrographis 15 parts, Rhizoma Polygoni Cuspidati 15 parts, Arillus Longan 10 parts, Herba Portulacae 15 parts, Caulis Polygoni Multiflori 15 parts, Fructus Forsythiae 10 parts, Herba Apocyni veneti 15 parts, Radix Glehniae 15 parts, Lignum Sappan 10 parts, Fructus Atriplicis Sibiricae 15 parts, Radix Polygalae 15 parts, Cortex Acanthopancis 15 parts, 15 parts of Herba Capsellae, 10 parts of Radix Glycyrrhizae。

Chinese medicine composition of the present invention is under Traditional Chinese medical theory and clinical experience instruct, selected medicament composing prescription。In Chinese medicine composition of the present invention: Herba Hedyotidis Diffusae has effect of heat-clearing and toxic substances removing, inducing diuresis to remove edema, promoting blood circulation and stopping pain；Semen Platycladi has effect of tranquilizing by nourishing the heart, nourishing YIN and benefiting blood；Radix Isatidis has effect of heat-clearing and toxic substances removing, removing heat from blood detumescence, sore-throat relieving；Effect that Fructus Ligustri Lucidi has nourishing the liver and kidney, tonifying YIN nourishes blood；Ramulus Cinnamomi has effect of diaphoresis expelling pathogenic factors from muscles, warming the meridian and promoting blood circulation, supporing yang activating QI, dispersing cold for relieving pain；Radix Oenotherae erythrosepalae has effect of wind-damp dispelling, bone and muscle strengthening, promoting blood circulation to remove obstruction in the collateral, endogenous wind stopping suppressing the hyperactive liver, detumescence sore；Lignum Dalbergiae Odoriferae has effect of promoting flow of QI and blood, pain relieving, hemostasis；There is Radix Ophiopogonis YIN nourishing and the production of body fluid promoting, effect that lung moistening clears away heart-fire；Herba Andrographis has effect of heat-clearing and toxic substances removing, antiinflammatory, reducing swelling and alleviating pain；Rhizoma Polygoni Cuspidati has effect of heat-clearing and toxic substances removing, promoting the function of the gallbladder to alleviate jaundice, expelling wind and removing dampness, dissipating blood stasis analgesic therapy, relieving cough and resolving phlegm；Arillus Longan has effect of invigorating the heart and spleen, nourishing blood to tranquillize the mind；Herba Portulacae has heat-clearing and toxic substances removing, diuretic dries, dissipate effect of blood detumescence, dust-collection sterilization, anti-inflammatory analgetic, hemostasis removing heat from blood；Caulis Polygoni Multiflori has effect of tranquilizing by nourishing the heart, dispelling wind and removing obstruction in the collateral；Fructus Forsythiae has effect of heat-clearing and toxic substances removing, mass dissipating and swelling eliminating；Herba Apocyni veneti have relieve inflammation or internal heat, blood pressure lowering, heart tonifying, diuresis effect；Radix Glehniae has effect of nourishing YIN and clearing away lung-heat, reinforcing stomach reg fluid；Lignum Sappan has effect of blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain；Fructus Atriplicis Sibiricae has effect of suppressing the hyperactive liver resolving depression, dispelling pathogenic wind for improving eyesight；Radix Polygalae has Fructus Alpiniae Oxyphyllae of calming the nerves, it is relieving convulsion to eliminate the phlegm, circulation of qi promoting dissipates strongly fragrant effect；Cortex Acanthopancis has effect of wind-damp dispelling, invigorating the liver and kidney, bone and muscle strengthening；Herba Capsellae have with spleen, heat clearing away, diuretic, detumescence, suppressing the hyperactive liver, hemostasis, improving eyesight effect；Radix Glycyrrhizae has effect of invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, coordinating the actions of various ingredients in a prescription。Drug component in the present composition, through dialectical compatibility, complements each other using, and has synergism, plays effect of reinforcing the heart strengthening the spleen, promoting flow of QI and blood, Yin-nourishing and body fluid promoting, anti-inflammatory analgetic altogether, and viral myocarditis reaches the purpose for the treatment of both the principal and secondary aspects of a disease。

The component of the present composition all adopts natural raw material of Chinese medicine, and preparation is easy, medicine source is wide, cost is low for it。It follows the prescriptions principle of the traditional Chinese medical science, and various component drug adopt the use that is decocted in water for oral dose。Verifying by clinic application, it is evident in efficacy, reliable effect, mild in medicine property and, toxic and side effects does not occur, total effective rate 86.6%, cure rate reaches 60%。

Detailed description of the invention

Below in conjunction with embodiment, the present invention will be further described。

Embodiment 1

A kind of Chinese medicine composition treating viral myocarditis, its raw material of Chinese medicine and weight proportion be: Herba Hedyotidis Diffusae 20g, Semen Platycladi 15g, Radix Isatidis 10g, Fructus Ligustri Lucidi 15g, Ramulus Cinnamomi 15g, Radix Oenotherae erythrosepalae 15g, Lignum Dalbergiae Odoriferae 10g, Radix Ophiopogonis 15g, Herba Andrographis 15g, Rhizoma Polygoni Cuspidati 15g, Arillus Longan 10g, Herba Portulacae 15g, Caulis Polygoni Multiflori 15g, Fructus Forsythiae 10g, Herba Apocyni veneti 15g, Radix Glehniae 15g, Lignum Sappan 10g, Fructus Atriplicis Sibiricae 15g, Radix Polygalae 15g, Cortex Acanthopancis 15g, Herba Capsellae 15g, Radix Glycyrrhizae 10g。

Embodiment 2

A kind of Chinese medicine composition treating viral myocarditis, its raw material of Chinese medicine and weight proportion be: Herba Hedyotidis Diffusae 10g, Semen Platycladi 20g, Radix Isatidis 5g, Fructus Ligustri Lucidi 20g, Ramulus Cinnamomi 10g, Radix Oenotherae erythrosepalae 20g, Lignum Dalbergiae Odoriferae 5g, Radix Ophiopogonis 20g, Herba Andrographis 10g, Rhizoma Polygoni Cuspidati 20g, Arillus Longan 5g, Herba Portulacae 20g, Caulis Polygoni Multiflori 10g, Fructus Forsythiae 15g, Herba Apocyni veneti 10g, Radix Glehniae 20g, Lignum Sappan 5g, Fructus Atriplicis Sibiricae 20g, Radix Polygalae 10g, Cortex Acanthopancis 20g, Herba Capsellae 10g, Radix Glycyrrhizae 15g。

Embodiment 3

A kind of Chinese medicine composition treating viral myocarditis, its raw material of Chinese medicine and weight proportion be: Herba Hedyotidis Diffusae 30g, Semen Platycladi 10g, Radix Isatidis 15g, Fructus Ligustri Lucidi 10g, Ramulus Cinnamomi 20g, Radix Oenotherae erythrosepalae 10g, Lignum Dalbergiae Odoriferae 15g, Radix Ophiopogonis 10g, Herba Andrographis 20g, Rhizoma Polygoni Cuspidati 10g, Arillus Longan 15g, Herba Portulacae 10g, Caulis Polygoni Multiflori 20g, Fructus Forsythiae 5g, Herba Apocyni veneti 20g, Radix Glehniae 10g, Lignum Sappan 15g, Fructus Atriplicis Sibiricae 10g, Radix Polygalae 20g, Cortex Acanthopancis 10g, Herba Capsellae 20g, Radix Glycyrrhizae 5g。

Embodiment 4

A kind of Chinese medicine composition treating viral myocarditis, its raw material of Chinese medicine and weight proportion be: Herba Hedyotidis Diffusae 15g, Semen Platycladi 18g, Radix Isatidis 8g, Fructus Ligustri Lucidi 18g, Ramulus Cinnamomi 12g, Radix Oenotherae erythrosepalae 18g, Lignum Dalbergiae Odoriferae 8g, Radix Ophiopogonis 18g, Herba Andrographis 12g, Rhizoma Polygoni Cuspidati 18g, Arillus Longan 8g, Herba Portulacae 18g, Caulis Polygoni Multiflori 12g, Fructus Forsythiae 13g, Herba Apocyni veneti 12g, Radix Glehniae 18g, Lignum Sappan 8g, Fructus Atriplicis Sibiricae 18g, Radix Polygalae 12g, Cortex Acanthopancis 18g, Herba Capsellae 12g, Radix Glycyrrhizae 13g。

Embodiment 5

A kind of Chinese medicine composition treating viral myocarditis, its raw material of Chinese medicine and weight proportion be: Herba Hedyotidis Diffusae 25g, Semen Platycladi 12g, Radix Isatidis 13g, Fructus Ligustri Lucidi 12g, Ramulus Cinnamomi 18g, Radix Oenotherae erythrosepalae 12g, Lignum Dalbergiae Odoriferae 13g, Radix Ophiopogonis 12g, Herba Andrographis 18g, Rhizoma Polygoni Cuspidati 12g, Arillus Longan 13g, Herba Portulacae 12g, Caulis Polygoni Multiflori 18g, Fructus Forsythiae 8g, Herba Apocyni veneti 18g, Radix Glehniae 12g, Lignum Sappan 13g, Fructus Atriplicis Sibiricae 12g, Radix Polygalae 18g, Cortex Acanthopancis 12g, Herba Capsellae 18g, Radix Glycyrrhizae 8g。

Chinese medicine composition in embodiment of the present invention decocting method routinely produces medicament。Concrete grammar is as follows: put in container by the raw material of Chinese medicine of prescription, adds cold water and covers powder, soak 15～20 minutes, adds water and do not have powder about 6 centimetres, carries out first time decoction, adopts intense fire to decoct before at a simmer, with slow fire boiling 20～30 minutes after boiling；Second time decocts, and adds water and did not have powder about 6 centimetres, and water decocts 15～20 minutes after boiling。Twice decoction is removed slag extracting juice, merges。

The present invention, with a kind of Chinese medicine composition treating viral myocarditis given by embodiment 1, does clinical efficacy and is summarized as follows:

One, general data: Chinese medicine composition of the present invention is applied to clinical observation case 60 example, wherein male 34 examples, female 26 example, 10～50 years old age。

Two, work up:

1, lab testing

(1) generally chemical examination: acute stage total white blood cells increases more, and neutrophilic granulocyte is main；Erythrocyte sedimentation rate can slightly speed；

(2) mensuration of myocardium enzyme: serum glutamic oxalacetic transaminase (AST), creatine phosphokinase (CK) and with T enzyme (CK-IVIB), lactic acid dehydrogenase (LDH), alpha-hydroxybutyric dehydrogenase (α-HBDH), all can raise in acute stage, serum cardiac troponin (cTnl or cTnT) is positive in acute stage, but cTnl or cTnT is positive or the rising of CK and the CK-MB diagnosis to myocardial damage。It addition, LDH is also valuable with T enzyme Serum enzyme spectrum analysis, normal LDH2 > LDH1 > LDH3 > LDH4 > LDH5, if LDH1/LDH2 ratio more than 1.0 or LDH1 >=total LDH40%, point out myocardial damage；

(3) virusology inspection: early stage can be separated to virus from feces, throat swab, blood or pericardial effusion, or use viral nucleic acid probe hybridization in situ in infant blood or detect viral RNA by polymerase chain reaction method。Raise at convalescent serum Isotype antibody titre relatively first part of serum or reduce by more than 4 times, or Specific IgM antibody is positive。Death can isolate virus in its pericardium, cardiac muscle or endocardium or specific fluorescent antibody checks the positive。Electron micrograph myocardial necrosis, it can be seen that virion near pathological changes；

2, x-ray, electrocardiogram, ambulatory electrocardiogram, ultrasoundcardiogram, myocardial injury markers monitoring, cardiac magnetic resonance imaging auxiliary examination are carried out。

Three, usage and dosage: during clinical practice, one day potion, twice extracting juice of decocting is about 300ml, and point early, late twice warm is taken, and within seven days, is a course for the treatment of。

Four, criterion of therapeutical effect:

1, curing: the performance such as the conscious cardiopalmus of patient, uncomfortable in chest, asthma is wholly absent, electrocardiogram recovers normal, and myocardium enzyme recovers normal, Color Sonography performance without exception；

2, effective: the performance such as the conscious cardiopalmus of patient, uncomfortable in chest, asthma significantly alleviates, and electrocardiogram recovers normal substantially, myocardium enzyme recovers normal, Color Sonography performance without exception；

3, effective: the performance such as the conscious cardiopalmus of patient, uncomfortable in chest, asthma alleviates, electrocardiogram mile abnormality, myocardium enzyme recovers normal, Color Sonography mile abnormality；

4, invalid: the performance such as the conscious cardiopalmus of patient, uncomfortable in chest, asthma does not alleviate, and electrocardiographic abnormality does not improve, myocardium enzyme is not improved, and Color Sonography does not improve。

Five, therapeutic effect: in this clinical observation case, take medicine 3-15 the course for the treatment of, 36 examples of fully recovering, effective 11 examples, effective 5 examples, invalid 8 examples。Toxic and side effects is there is not during treatment。

Six, model case:

Case 1: Wang, man, 19 years old。Readme morbidity has the symptoms such as heating, pharyngalgia, cough, muscular soreness in previous many weeks, but does not pay attention to。Fainted because of arrhythmia later, after recovering through rescue, cardiopalmus, the symptom such as nervous occurred, and through every inspection, diagnosed and be: viral myocarditis。After 4 courses for the treatment of of medicament taking prepared by the Chinese medicine composition of the present invention, cardiopalmus, nervous symptom alleviate；After continuing to take 3 courses for the treatment of, all transference cures, health is normal with livelihood restoration, recovery from illness。

Case 2: Zhang, female, 41 years old。Readme from the beginning of time have the symptoms such as diarrhoea, vomiting, headache, just have after one month nervous, breathe hard, asthenia unable, lassitude, intermittent heart beating aggravation with distressed, dyspnea。Through laboratory, virusology inspection, diagnose and be: viral myocarditis。After 3 courses for the treatment of of medicament taking prepared by the Chinese medicine composition of the present invention, cardiopalmus, dyspnea symptom substantially alleviate, and muscle power is recovered to some extent；Continuing after taking 3 courses for the treatment of, the mental status is good, and livelihood restoration is normal, the transference cure such as cardiopalmus, dyspnea, recovery from illness。

Claims

1. the Chinese medicine composition treating viral myocarditis, it is characterized in that: its raw material of Chinese medicine and weight be: Herba Hedyotidis Diffusae 10-30 part, Semen Platycladi 10-20 part, Radix Isatidis 5-15 part, Fructus Ligustri Lucidi 10-20 part, Ramulus Cinnamomi 10-20 part, Radix Oenotherae erythrosepalae 10-20 part, Lignum Dalbergiae Odoriferae 5-15 part, Radix Ophiopogonis 10-20 part, Herba Andrographis 10-20 part, Rhizoma Polygoni Cuspidati 10-20 part, Arillus Longan 5-15 part, Herba Portulacae 10-20 part, Caulis Polygoni Multiflori 10-20 part, Fructus Forsythiae 5-15 part, Herba Apocyni veneti 10-20 part, Radix Glehniae 10-20 part, Lignum Sappan 5-15 part, Fructus Atriplicis Sibiricae 10-20 part, Radix Polygalae 10-20 part, Cortex Acanthopancis 10-20 part, Herba Capsellae 10-20 part, Radix Glycyrrhizae 5-15 part。

2. a kind of Chinese medicine composition treating viral myocarditis according to claim 1, it is characterised in that: its raw material of Chinese medicine and weight be: Herba Hedyotidis Diffusae 20 parts, Semen Platycladi 15 parts, Radix Isatidis 10 parts, Fructus Ligustri Lucidi 15 parts, Ramulus Cinnamomi 15 parts, Radix Oenotherae erythrosepalae 15 parts, Lignum Dalbergiae Odoriferae 10 parts, Radix Ophiopogonis 15 parts, Herba Andrographis 15 parts, Rhizoma Polygoni Cuspidati 15 parts, Arillus Longan 10 parts, Herba Portulacae 15 parts, Caulis Polygoni Multiflori 15 parts, Fructus Forsythiae 10 parts, Herba Apocyni veneti 15 parts, Radix Glehniae 15 parts, Lignum Sappan 10 parts, Fructus Atriplicis Sibiricae 15 parts, Radix Polygalae 15 parts, Cortex Acanthopancis 15 parts, 15 parts of Herba Capsellae, 10 parts of Radix Glycyrrhizae。