CN104383054A - Traditional Chinese medicine composition curing constipation after apoplexy - Google Patents

Traditional Chinese medicine composition curing constipation after apoplexy Download PDF

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CN104383054A
CN104383054A CN201410572735.1A CN201410572735A CN104383054A CN 104383054 A CN104383054 A CN 104383054A CN 201410572735 A CN201410572735 A CN 201410572735A CN 104383054 A CN104383054 A CN 104383054A
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chinese medicine
medicine composition
traditional chinese
radix
constipation
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詹霞
周丽
于丽瑛
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/708Rheum (rhubarb)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/62Leeches; Worms, e.g. cestodes, tapeworms, nematodes, roundworms, earth worms, ascarids, filarias, hookworms, trichinella or taenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • A61K35/648Myriapods, e.g. centipedes or millipedes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286Carthamus (distaff thistle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/34Campanulaceae (Bellflower family)
    • A61K36/344Codonopsis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/57Magnoliaceae (Magnolia family)
    • A61K36/575Magnolia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/752Citrus, e.g. lime, orange or lemon

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Abstract

The invention relates to a traditional Chinese medicine composition curing constipation after apoplexy. The traditional Chinese medicine composition comprises the following raw materials in parts by weight: 10-20 g of fried rheum officinale, 5-20 g of immature bitter orange, 5-20 g of officinal magnolia bark, 5-20 g of safflower, 10-20 g of lumbricus, 5-10 g of centipede, 10-30 g of hoantchy root, 10-25 g of radix codonopsitis, and 6-9 g of honey-fried licorice root. The traditional Chinese medicine composition adopts natural traditional Chinese medicine raw materials, has the efficacy of purging heat, smoothing intestine, cooling blood, disintoxicating, relieving stagnant qi, removing food retention, descending qi, eliminating fullness, dredging collaterals, dispersing stasis, relieving pain, counteracting toxic substances, dissipating stagnation, invigorating qi for consolidating superficies, strengthening the spleen, and tonifying lung, and is simple and convenient to prepare, broad in medicinal herbs resource, low in cost, remarkable in curative effect, mild in medicine property; the effective rate reaches 96.67%; the cure rate reaches 75%.

Description

A kind of Chinese medicine composition for the treatment of poststroke constipation
Technical field
The present invention relates to a kind of medicinal preparation not determining structure of traditional herbal medicines, specifically a kind of Chinese medicine composition for the treatment of poststroke constipation.
Background technology
Apoplexy is common complaint among the elderly, is also to endanger one of three kinds of maximum diseases to the mankind.Constipation is a kind of common symptom after apoplexy, due to after apoplexy because Colon Movement, defecation reflex are influenced, adding that bed is few dynamic, amount of liquid is not enough, feed less, meticulous few slag, lack dietary fiber and cause constipation.Paralytic is too firmly defecation due to constipation, and abdominal pressure is increased, and heart contraction is strengthened, and blood pressure raises, and easily brings out again or increases the weight of original state of an illness, becoming vicious cycle.In recent years, due to the raising for the treatment of level, the mortality rate of apoplexy declines to some extent, but clinically to poststroke constipation without special good medicine, mostly adopt cathartic to be main, and easily dependency produced to medicine, easily recur after drug withdrawal.
The traditional Chinese medical science is thought, diet enters stomach, and through transporting and transforming function of the spleen and stomach, after absorbing its elite, remaining waste matter is finally gone out by the large intestine development of evil in febrile disease, then becomes stool.The multifactor bromhidrosis of the patient of poststroke constipation is empty, can not promote stool and go out, and defecates at large intestine with the passing of time and drying is difficult to resolve, capture as gone for a long time by mistake, injure the taste then deficiency of vital energy, the deficiency of vital energy is retention of water-damp then, strongly fragrant and heat-dissipating, damp and hot interior life, then clear YANG failing to ascend, turbid YIN failing to descend, obstructed up and down, constipation is heavier, causes simulataneous insufficiency and excessive and refractory.
According to theory of Chinese medical science, for the pathogeny of poststroke constipation, carry out dialectical composition of prescription, to reach the object for the treatment of both the principal and secondary aspects of a disease.
Summary of the invention
The present invention is directed to the deficiencies in the prior art, according to theory of Chinese medical science, by drug screening and the clinical verification repeatedly of several years, provide a kind of compatibility reasonable, medicine source is wide, and cost is low, evident in efficacy, the Chinese medicine composition of the treatment poststroke constipation had no side effect.
The technical solution adopted for the present invention to solve the technical problems is: a kind of Chinese medicine composition for the treatment of poststroke constipation, it is characterized in that what it was made up of the raw material of Chinese medicine of following weight proportion: Radix et Rhizoma Rhei (processed) 10-20g, Fructus Aurantii Immaturus 5-20g, Cortex Magnoliae Officinalis 5-20g, Flos Carthami 5-20g, Pheretima 10-20g, Scolopendra 5-10g, Radix Astragali 10-30g, Radix Codonopsis 10-25g, Radix Glycyrrhizae Preparata 6-9g.
The preferred technical solution of the present invention is: a kind of Chinese medicine composition for the treatment of poststroke constipation, it is characterized in that what it was made up of the raw material of Chinese medicine of following weight proportion: Radix et Rhizoma Rhei (processed) 12g, Fructus Aurantii Immaturus 10g, Cortex Magnoliae Officinalis 10g, Flos Carthami 10g, Pheretima 10g, Scolopendra 6g, Radix Astragali 15g, Radix Codonopsis 10g, Radix Glycyrrhizae Preparata 6g.
Chinese medicine composition of the present invention is under Traditional Chinese medical theory and clinical experience instruct, selected medicament composing prescription.In Chinese medicine composition of the present invention: Radix et Rhizoma Rhei (processed) [nature and flavor] is bitter, cold.[return through] returns spleen, stomach, large intestine, liver, pericardium channel.[function cures mainly] purging heat and dredging bowels, removing pathogenic heat from blood and toxic substance from the body, eliminating blood stasis and inducing menstruation.For excess-heat constipation, stagnant stomachache, dysentery is not well, jaundice due to damp-heat, and heat in blood tells nosebleed, conjunctival congestion, pharyngeal swelling, abdominalgia with intestinal abscess, carbuncle furuncle, blood stasis amenorrhea, traumatic injury, external treatment burn due to hot liquid or fire; Upper gastrointestinal hemorrhage.Radix et Rhizoma Rhei (stir-fried with wine) is apt to clear part of the body cavity above the diaphragm housing the heart and lungs noxious heat in the blood system.For conjunctival congestion pharyngeal swelling, gingivitis.Radix Et Rhizoma Rhei rushes down exerts oneself to delay, eliminating fire and detoxication.For pathogenic fire,toxin and furuncles.Charred Radix Et Rhizoma Rhei cooling blood and removing stasis stops blooding.Stasis of blood hemorrhage is had for heat in blood.Fructus Aurantii Immaturus [nature and flavor] is bitter, pungent, sour, temperature.[return through] returns spleen, stomach warp.[function cures mainly] dispelling the stagnated QI removing food stagnancy, loose painful abdominal mass of reducing phlegm.Stop in stagnant, feeling of fullness distending pain, heavy after dysentery, constipation, the stagnant vapour lock thoracic obstruction of expectorant, blocked-up chest; Gastroptosis, proctoptosis, uterine prolapse.Cortex Magnoliae Officinalis [nature and flavor] is bitter, pungent, temperature.[return through] returns spleen, stomach, lung, large intestine channel.The expectorant of [function cures mainly] dampness, the therapeutic method to keep the adverse QI flowing downwards is except full.For humidity hysteresis damaging the spleen and stomach, gastral cavity painful abdominal mass is vomited and diarrhoea, and stagnation of QI due to dyspepsia, abdominal distention constipation, phlegm retention is breathed with cough.Flos Carthami [nature and flavor] is pungent, temperature.[return through] GUIXIN, Liver Channel.[function cures mainly] promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain.For amenorrhea, dysmenorrhea, lochia, lump in the abdomen mass in the abdomen, injury from falling down, skin infection swells and ache.Pheretima [nature and flavor] is salty, cold.[return through] returns liver, spleen, urinary bladder channel.[function cures mainly] heat clearing away is calmed the frightened, and dredging collateral, relievings asthma, diuresis.For unconsciousness due to high fever, infantile convulsion is twitched, arthralgia, numb limbs and tense tendons, hemiplegia, dyspnea and cough due to lung-heat, oliguria edema, hypertension.Scolopendra [nature and flavor] is pungent, temperature; Poisonous.[return through] returns Liver Channel.[function cures mainly] endogenous wind stopping spasmolytic, merit poison eliminating stagnation, removing obstruction in the collateral to relieve pain.For infantile convulsion, tic spasm, middle air port is askew, hemiplegia, tetanus, rheumatoid arthritis stubborn, skin infection, scrofula, venom.The Radix Astragali [nature and flavor] is sweet, temperature.[return through] returns lung, spleen channel.[function cures mainly] invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.Weak for the deficiency of vital energy, anorexia and loose stool, sinking of QI of middle-JIAO, chronic diarrhea proctoptosis, metrorrhagia of having blood in stool, exterior deficiency spontaneous perspiration, deficiency of vital energy edema, carbuncle difficulty is burst, and burst for a long time and do not hold back, blood deficiency dull yellowish colored skin, interior-heat is quenched one's thirst; Chronic nephritis proteinuria, diabetes.Radix Codonopsis [nature and flavor] is sweet, flat.[return through] returns spleen, lung meridian.[function cures mainly] invigorating the spleen and replenishing QI, spleen invigorating lung benefiting.For deficiency of the spleen and lung, cardiopalmus of breathing hard, anorexia and loose stool, dyspnea due to deficiency is coughed, and interior-heat is quenched one's thirst.Radix Glycyrrhizae Preparata [nature and flavor] is sweet, flat.[return through] GUIXIN, lung, spleen, stomach warp.[function cures mainly] invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.The present invention has purging heat and dredging bowels, removing pathogenic heat from blood and toxic substance from the body, dispelling the stagnated QI removing food stagnancy, and the therapeutic method to keep the adverse QI flowing downwards is except full, and dredging collateral eliminating stasis to stop pain, merit poison eliminating stagnation, invigorating QI to consolidate the body surface resistance, spleen invigorating lung benefiting, reaches the object for the treatment of both the principal and secondary aspects of a disease to poststroke constipation.
The component of the present composition all adopts natural raw material of Chinese medicine, and its preparation is easy, medicine source is wide, cost is low.It follows the prescriptions principle of the traditional Chinese medical science, and various component drug adopts the use that is decocted in water for oral dose.Through clinical practice checking, it is evident in efficacy, reliable effect, mild in medicine property and, do not occur toxic and side effects, total effective rate 96.67%, cure rate reaches 75%.
Detailed description of the invention
Embodiment 1: a kind of Chinese medicine composition for the treatment of poststroke constipation, is characterized in that what it was made up of the raw material of Chinese medicine of following weight proportion: Radix et Rhizoma Rhei (processed) 12g, Fructus Aurantii Immaturus 10g, Cortex Magnoliae Officinalis 10g, Flos Carthami 10g, Pheretima 10g, Scolopendra 6g, Radix Astragali 15g, Radix Codonopsis 10g, Radix Glycyrrhizae Preparata 6g.
Embodiment 2: a kind of Chinese medicine composition for the treatment of poststroke constipation, is characterized in that what it was made up of the raw material of Chinese medicine of following weight proportion: Radix et Rhizoma Rhei (processed) 10g, Fructus Aurantii Immaturus 20g, Cortex Magnoliae Officinalis 5g, Flos Carthami 15g, Pheretima 20g, Scolopendra 8g, Radix Astragali 30g, Radix Codonopsis 25g, Radix Glycyrrhizae Preparata 6g.
Embodiment 3: a kind of Chinese medicine composition for the treatment of poststroke constipation, is characterized in that what it was made up of the raw material of Chinese medicine of following weight proportion: Radix et Rhizoma Rhei (processed) 15g, Fructus Aurantii Immaturus 12g, Cortex Magnoliae Officinalis 15g, Flos Carthami 20g, Pheretima 12g, Scolopendra 5g, Radix Astragali 20g, Radix Codonopsis 15g, Radix Glycyrrhizae Preparata 9g.
Embodiment 4: a kind of Chinese medicine composition for the treatment of poststroke constipation, is characterized in that what it was made up of the raw material of Chinese medicine of following weight proportion: Radix et Rhizoma Rhei (processed) 15g, Fructus Aurantii Immaturus 15g, Cortex Magnoliae Officinalis 20g, Flos Carthami 10g, Pheretima 15g, Scolopendra 10g, Radix Astragali 10g, Radix Codonopsis 20g, Radix Glycyrrhizae Preparata 6g.
Embodiment 5: a kind of Chinese medicine composition for the treatment of poststroke constipation, is characterized in that what it was made up of the raw material of Chinese medicine of following weight proportion: Radix et Rhizoma Rhei (processed) 20g, Fructus Aurantii Immaturus 5g, Cortex Magnoliae Officinalis 10g, Flos Carthami 5g, Pheretima 10g, Scolopendra 5g, Radix Astragali 25g, Radix Codonopsis 20g, Radix Glycyrrhizae Preparata 9g.
Chinese medicine composition in embodiment of the present invention decocting method routinely produces medicament.Concrete grammar is as follows: container put into by the raw material of Chinese medicine medicine getting prescription of the present invention, first soak, add cold water and cover powder, soak 20 ~ 30 minutes, add water again and do not have powder about 10 centimetres, carry out first time decoction, first decoct with high heat, boil rear slow fire boiling 20 ~ 30 minutes, leach the juice 200ml that gets it filled; Second decocts, and adds water and does not have powder about 6 centimetres, decocts 20 ~ 25 minutes, leach the juice 200ml that gets it filled after water boils.Twice decoction obtains medicinal liquid juice and merges.
Treat a Chinese medicine composition for poststroke constipation, clinical efficacy is summed up:
One, general data: this Chinese medicine composition is applied to clinical observation case 60 example, wherein man 33 example, female 27 example, 55 ~ 75 years old age.The shortest person of the course of disease 6 months, most elder reaches 5 years.
Two, diagnostic criteria: all cases all meet the related diagnosis standard formulated in the disease of tcm Standardization of diagnosis and curative effect of State Administration of Traditional Chinese Medicine's issue in 1994.
Three, usage and dosage: during clinical practice, the component in compositions, consumption take the circumstances into consideration increase and decrease according to the body weight of patient, age and symptom.Within seven days, be a course for the treatment of, one day potion, decocting twice extracting juice is about 400ml, and point early, late twice half an hour ante cibum warmly take.
Four, criterion of therapeutical effect:
Cure: clinical cardinal symptom and sign disappear, and constipation is pass on well slightly.
Effective: cardinal symptom obviously alleviates, constipation alleviates to some extent.
Invalid; Cardinal symptom is unchanged, does not also worsen.
Five, therapeutic effect: in clinical observation case, takes medicine 1-6 the course for the treatment of, cures 45 examples, effective 13 examples, invalid 2 examples.There is not toxic and side effects in treatments period.
Six, model case:
1, Wang, man, 62 years old, after apoplexy 1 year, defecates 2 times for one week, difficult defecation, and take 4 courses for the treatment of of medicament prepared by Chinese medicine composition of the present invention, within one week, defecation frequency increases, and feces volume increases.
2, Lee, female, 60 years old, lie in bed 3 years after apoplexy, defecation is dry, hard, takes 3 courses for the treatment of of medicament prepared by Chinese medicine composition of the present invention, and stool shape obviously changes, and symptom is alleviated to some extent.

Claims (2)

1. treat a Chinese medicine composition for poststroke constipation, it is characterized in that what it was made up of the raw material of Chinese medicine of following weight proportion: Radix et Rhizoma Rhei (processed) 10-20g, Fructus Aurantii Immaturus 5-20g, Cortex Magnoliae Officinalis 5-20g, Flos Carthami 5-20g, Pheretima 10-20g, Scolopendra 5-10g, Radix Astragali 10-30g, Radix Codonopsis 10-25g, Radix Glycyrrhizae Preparata 6-9g.
2. a kind of Chinese medicine composition for the treatment of poststroke constipation according to claim 1, is characterized in that what it was made up of the raw material of Chinese medicine of following weight proportion: Radix et Rhizoma Rhei (processed) 12g, Fructus Aurantii Immaturus 10g, Cortex Magnoliae Officinalis 10g, Flos Carthami 10g, Pheretima 10g, Scolopendra 6g, Radix Astragali 15g, Radix Codonopsis 10g, Radix Glycyrrhizae Preparata 6g.
CN201410572735.1A 2014-10-20 2014-10-20 Traditional Chinese medicine composition curing constipation after apoplexy Pending CN104383054A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106389602A (en) * 2016-05-17 2017-02-15 长春中医药大学附属医院 Pharmaceutical composition for treating syndromes of phlegm heat and bowel repletion of stroke and preparation method of pharmaceutical composition

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
林新锋等: "通络法治疗中风急性期42例疗效观察", 《新中医》 *
王晓萍: "小承气汤配合中药穴位贴敷治疗中风后便秘的临床观察", 《西部中医药》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106389602A (en) * 2016-05-17 2017-02-15 长春中医药大学附属医院 Pharmaceutical composition for treating syndromes of phlegm heat and bowel repletion of stroke and preparation method of pharmaceutical composition

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Application publication date: 20150304