CN102716262B - Traditional Chinese medicine formula for curing ankylosing spondylitis - Google Patents

Abstract

A traditional Chinese medicine formula for curing AS (Ankylosing Spondylitis) is characterized in that the traditional Chinese medicine comprises the followings according to proportion of ingredients: 7.6 to 7.7 percent of atractylis ovata, 5.2 to 5.3 percent of white paeony roots, 7.3 to 7.4 percent of rhizoma cibotii, 6.3 to 6.5 percent of loranthus parasiticus, 5.4 to 5.5 percent of roots of rehmannia, 5.6 to 5.7 percent of drynaria rhizome, 6.6 to 6.7 percent of notopterygium roots, 6.2 to 6.3 percent of radix angelicae pubescentis, 4.8 to 5.0 percent of processed radix aconiti lateralis, 4.9 to 5.0 percent of pangolin scales, 0.4 to 0.5 percent of scrophularia, 6.7 to 6.8 percent of membranous milkvetch roots, 3.9 to 4.0 percent of medlar, 1.5 to 1.6 percent of wild ginger, 4.9 to 5.0 percent of achyranthis roots, 4.9 to 5.0 percent of stir-baked plastrum testudinis before treated with Vinegar, 4.9 to 5.0 percent of dried orange peel, and 4.9 to 5.0 percent of honey-fried licorice roots. The traditional Chinese medicine formula solves the problems of poor medicine effect and big side effects in conventional medicine for curing AS, and is suitable for being used for curing AS.

Description

A kind of Chinese medicine formula for the treatment of ankylosing spondylitis

Technical field

The present invention relates to Chinese medicine and make field, is a kind of Chinese medicine formula for the treatment of ankylosing spondylitis specifically.

Background technology

Ankylosing spondylitis (AS) is a kind of chronic inflammation illness of involving spinal column and sacroiliac joint that autoimmune is feature of take, and is world today's difficult miscellaneous diseases.Population of China prevalence is in 3 ‰ left and right, 10-30 year be ankylosing spondylitis (AS) easily send out the age, teenager is its colony that is mainly injured.This cause of disease makes a definite diagnosis that difficulty is large, misdiagnosis rate is high in early days, makes a definite diagnosis rear Chang Yinwu specific medicament and difficulty is played good effect, causes patient's disability rate high, causes certain burden to society and family.The Therapeutic Method of modern medicine is mainly by immunosuppressant such as oral Non-steroidanalgetic drug (NSAIDS) and application hydrocortisone parahormones, reach recent lenitive therapeutic purposes, be difficult to fundamentally reach clinical cure ankylosing spondylitis (AS), weak curative effect, the course for the treatment of is long, relapse rate is high, and drug side effect used is large.

Summary of the invention

The present invention is not good for the effect of drugs of the existing treatment ankylosing spondylitis of solution, and the course for the treatment of is long, and relapse rate is high, and the problem that side effect is large is invented a kind of Chinese medicine formula for the treatment of ankylosing spondylitis.

Technical scheme of the present invention is, a kind of Chinese medicine formula for the treatment of ankylosing spondylitis, and its special character is:

Constituent is: the Rhizoma Atractylodis Macrocephalae, the Radix Paeoniae Alba, Rhizoma Cibotii, Herba Taxilli, the Radix Rehmanniae, Rhizoma Drynariae, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Radix Aconiti Lateralis Preparata, process Squama Manis, Radix Scrophulariae, the Radix Astragali, Fructus Lycii, Herba Asari, Radix Achyranthis Bidentatae, Carapax Et Plastrum Testudinis (processed), Pericarpium Citri Reticulatae, Radix Glycyrrhizae Preparata;

Component ratio is: Rhizoma Atractylodis Macrocephalae 7.6-7.7%, Radix Paeoniae Alba 5.2-5.3%, Rhizoma Cibotii 7.3-7.4%, Herba Taxilli 6.3-6.5%, Radix Rehmanniae 5.4-5.5%, Rhizoma Drynariae 5.6-5.7%, Rhizoma Et Radix Notopterygii 6.6-6.7%, Radix Angelicae Pubescentis 6.2-6.3%, Radix Aconiti Lateralis Preparata 4.8-5.0%, process Squama Manis 4.9-5.0%, Radix Scrophulariae 6.4-6.5%, Radix Astragali 6.7-6.8%, Fructus Lycii 3.9-4.0%, Herba Asari 1.5-1.6%, Radix Achyranthis Bidentatae 4.9-5.0%, Carapax Et Plastrum Testudinis (processed) 4.9-5.0%, Pericarpium Citri Reticulatae 4.9-5.0%, Radix Glycyrrhizae Preparata 4.9-5.0%.

Make instructions of taking: take by weight above-mentioned medical material and mix, put into medicinal cupping and add 3 bowls of water soakings 3 hours, first with vigorous fire, boil, then use slow fire instead and decoct slowly about 30-40 minute, decoct to surplus 1 bowl of medicinal liquid, leach medicinal liquid, preserve medicinal residues.Decoct for the 2nd time, the 3rd time and add respectively 2 bowls of water, same vigorous fire boils, and changes slow fire and decocts slowly about 20-30 minute, decocts to surplus half bowl of medicinal liquid, leaches medicinal liquid.The medicinal liquid decocting for three times is mixed, is divided into 2 equal portions, early, evening each decoction being taken warmly a, after clothes, flat bed rest is 30 minutes.1 dose of every day, 18 doses is a course for the treatment of.

Modern medicine thinks that the pathological characters of ankylosing spondylitis is autoimmune response, it is the main rule for the treatment of that medicine in formula be take the loose wind of the kidney invigorating cold relieving, removing dampness, the flourish muscle of nourishing the liver, eliminating blood stasis and smoothing collaterals, there is the kidney invigorating cold relieving, blood circulation promoting and blood stasis dispelling, adjusting immunity, improve microcirculation, be conducive to the removing of immune complex and the reparation of pathological tissues.

Technique effect

Technique effect of the present invention is, adopts above-mentioned technical scheme, can realize a kind of pharmaceutical formulation that utilizes treatment by Chinese herbs ankylosing spondylitis, there is the health of help strengthening vital QI to eliminate pathogenic factors, treating both the principal and secondary aspects of a disease, expelling wind and removing dampness, easing joint movement, the effect of the kidney invigorating dispersing cold for relieving pain, bone and muscle strengthening.Curative effect of medication is remarkable, without any side effects, short treating period, and expense is low, is the good medicine of strengthening vital QI to eliminate pathogenic factors, reinforcement and elimination in combination.From in March, 1993 so far, apply this side treatment more than 5,000 examples, every patient, according to clinical dialectical, with 1/2 dose of disease plus-minus, every day early, late decoction being taken warmly 2 times, 18 doses was 1 course for the treatment of, effective percentage 100%.

Model case 1: all x, man, 36 years old, admission number 21455.Because 8 years companion's left lower extremity paroxysmal pain fiber crops of the stiff pain of lower back are admitted to hospital on May 6th, 1994 for 1 year.8 years causes of patient are got injured by a fall and are occurred that lumbosacral region aches after lumbosacral region, diseases caused by exogenous pathogenic factor rheumatism, and light night in daytime is heavy, increase the weight of gradually, morning stiff time 30-60 minute.Disease is seen Thoracolumbar limitation of activity, curved, the sacroiliac joint tenderness in lumbar vertebra left side.Red tongue, yellow and greasy fur, slippery and rapid pulse.Blood Hb95g/L, ESR32mm/h, CIC is positive.X line shows that sacroiliac joint gap is crude, articular surface hardens, right side cystis degeneration; There is " three lines are levied " in breast lumbar vertebra.Diagnosis: ankylosing spondylitis (AS) (the mark pattern of fever of suffering from a deficiency of the kidney).Prescription: Rhizoma Cibotii, the Radix Rehmanniae, each 30g of Radix Scrophulariae, Herba Taxilli, Rhizoma Drynariae, the Rhizoma Atractylodis Macrocephalae, the Radix Paeoniae Alba, each 12g of Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis 15g, Radix Aconiti Lateralis Preparata, processs each 6g of Squama Manis, Carapax Et Plastrum Testudinis (processed), the Radix Astragali, Fructus Lycii, Pericarpium Citri Reticulatae, Radix Glycyrrhizae Preparata, each 9g of Radix Achyranthis Bidentatae, Herba Asari 3g.Be decocted in water for oral dose, 1 dose of day, serve on 9 doses.Lumbago and skelalgia obviously alleviates.Pale tongue, tongue is greasy in vain, and deep pulse is fine and smooth.Mark hot clearly.Top plus-minus, serve on 9 doses, and patient's subjective symptoms disappears, movable as usual.On May 27th, 1994, leave hospital.Follow up a case by regular visits to March, stable curative effect.

Model case 2: Xu x, female, 36 years old, admission number 24889.Because the two lower limb paroxysmal pain of the stiff pain companion of lower back fiber crops are admitted to hospital on February 25th, 1997 for more than 3 years.The heavy stiff pain of patient back sacrum portion acid, light night in daytime is heavy, increases the weight of gradually, and morning is obviously stiff.Disease is seen protruding distortion after Thoracolumbar limitation of activity, lumbar vertebra, sacroiliac joint tenderness.Red tongue, yellow and greasy fur, slippery and rapid pulse.Blood Hb120g/L, ESR26mm/h, CIC is positive.X line shows that sacroiliac joint gap is crude, articular surface hardens, cystis degeneration; There is " square change " in breast lumbar vertebra.Diagnosis: ankylosing spondylitis (AS) (the mark pattern of fever of suffering from a deficiency of the kidney).Prescription: Rhizoma Cibotii, the Radix Rehmanniae, each 20g of Radix Scrophulariae, Herba Taxilli 15g, Rhizoma Drynariae, the Rhizoma Atractylodis Macrocephalae, the Radix Paeoniae Alba, each 12g of Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis 15g, Radix Aconiti Lateralis Preparata, processs Squama Manis, Carapax Et Plastrum Testudinis (processed), the Radix Astragali, Fructus Lycii, Pericarpium Citri Reticulatae, Radix Glycyrrhizae Preparata, each 9g of Radix Achyranthis Bidentatae, Herba Asari 3g.Be decocted in water for oral dose, 1 dose of day, serve on 9 doses.Lumbago and skelalgia obviously alleviates.Pale tongue, tongue is greasy in vain, and deep pulse is fine and smooth.Mark hot clearly.Top plus-minus, serve on 9 doses, and patient's subjective symptoms disappears, movable as usual.On March 12nd, 1997, leave hospital.Follow up a case by regular visits to stable curative effect 1 year.

Model case 3: Lee x, man, 27 years old, examined June 12 calendar year 2001.The stiff pain of patient's neck lower back, looks wane and sallow, tired unable more than 1 year.Chemical examination Hb110g/L, RF (-), ESR17mm/h, CIC is positive.X line shows that cervical curvature straightens, and slight left side is curved, right lateral bend that thoracic vertebra is slight, and lumbar vertebra is slight, and left side is curved.Sacroiliac joint gap disappears, and is half fusion.Pale tongue, tongue is greasy in vain, deep pulse.Diagnosis: ankylosing spondylitis (AS) (BI-syndrome involved the kidney, asthenic cold type).Prescription: Rhizoma Cibotii, each 30g of Radix Scrophulariae, the Radix Astragali, each 20g of Herba Taxilli, Rhizoma Drynariae, the Rhizoma Atractylodis Macrocephalae, Radix Achyranthis Bidentatae, each 12g of Rhizoma Et Radix Notopterygii, the Radix Paeoniae Alba, Radix Angelicae Pubescentis 15g, Radix Aconiti Lateralis Preparata, Carapax Et Plastrum Testudinis (processed), process Squama Manis, Fructus Lycii, Pericarpium Citri Reticulatae, the Radix Rehmanniae, each 9g of Radix Glycyrrhizae Preparata, Herba Asari 3g.Be decocted in water for oral dose, 1/2 dose, day 2 times, decoction being taken warmly, flat bed rest after clothes, serve on 9 doses.Calendar year 2001 further consultation on June 21, lumbago and skelalgia obviously alleviates.Pale tongue, white and thin fur, stringy pulse.Top plus-minus, continues by the method for the kidney invigorating cold relieving, serve on 9 doses.Examine June 30 calendar year 2001 again, and patient's subjective symptoms disappears, movable as usual.The ESR7mm/h that has a blood test, CIC is negative.Follow up a case by regular visits to stable curative effect 1 year.

The specific embodiment

Embodiment 1:

Take Rhizoma Cibotii 30g, Radix Rehmanniae 20g, Herba Taxilli, each 15g of Radix Angelicae Pubescentis, Radix Scrophulariae, Rhizoma Drynariae, the Rhizoma Atractylodis Macrocephalae, the Radix Paeoniae Alba, each 12g of Rhizoma Et Radix Notopterygii, Radix Aconiti Lateralis Preparata, process each 6g of Squama Manis, Carapax Et Plastrum Testudinis (processed), the Radix Astragali, Fructus Lycii, Pericarpium Citri Reticulatae, Radix Glycyrrhizae Preparata, each 9g of Radix Achyranthis Bidentatae, Herba Asari 3g.(209g altogether)

Make instructions of taking: take by weight above-mentioned medical material and mix and put into medicinal cupping, add 3 bowls of water soakings 3 hours, with vigorous fire, boil, use slow fire instead and decoct slowly, about 30-40 minute, decocts to surplus 1 bowl of medicinal liquid, leaches medicinal liquid, preservation medicinal residues.Add respectively 2 bowls of water the 2nd time, the 3rd time, same vigorous fire boils, and changes slow fire and decocts slowly, and about 20-30 minute, decocts to surplus half bowl of medicinal liquid, leaches medicinal liquid.The medicinal liquid decocting for three times is mixed, is divided into 2 equal portions, early, evening each decoction being taken warmly a, after clothes, flat bed rest is 30 minutes.1 dose of every day, 18 doses is a course for the treatment of.

Embodiment 2:

Take Rhizoma Cibotii 18, the Radix Rehmanniae 16, Herba Taxilli 12g, Radix Angelicae Pubescentis 12g, Radix Scrophulariae, Rhizoma Drynariae, the Rhizoma Atractylodis Macrocephalae, the Radix Paeoniae Alba, each 8g of Rhizoma Et Radix Notopterygii, Radix Aconiti Lateralis Preparata, process each 4g of Squama Manis, Carapax Et Plastrum Testudinis (processed), the Radix Astragali, Fructus Lycii, Pericarpium Citri Reticulatae, Radix Glycyrrhizae Preparata, each 5g of Radix Achyranthis Bidentatae, Herba Asari 3g.(139g altogether)

Make instructions of taking: take by weight above-mentioned medical material and mix and put into medicinal cupping, add 3 bowls of water soakings after 3 hours, with vigorous fire, boil, use slow fire instead and decoct slowly, about 30-40 minute, decocts to surplus 1 bowl of medicinal liquid, leaches medicinal liquid, preservation medicinal residues.Decoct for the 2nd time, the 3rd time and add respectively 2 bowls of water, same vigorous fire boils, and changes slow fire and decocts slowly, and about 20-30 minute, decocts to surplus half bowl of medicinal liquid, leaches medicinal liquid.The medicinal liquid decocting for three times is mixed, is divided into 2 equal portions, early, evening each decoction being taken warmly a, after clothes, flat bed rest is 30 minutes.1 dose of every day, 18 doses is a course for the treatment of.

Embodiment 3:

Take Rhizoma Cibotii 35g, Radix Rehmanniae 25g, Herba Taxilli, each 16g of Radix Angelicae Pubescentis, Radix Scrophulariae, Rhizoma Drynariae, the Rhizoma Atractylodis Macrocephalae, the Radix Paeoniae Alba, each 15g of Rhizoma Et Radix Notopterygii, Radix Aconiti Lateralis Preparata, process each 8g of Squama Manis, Carapax Et Plastrum Testudinis (processed), the Radix Astragali, Fructus Lycii, Pericarpium Citri Reticulatae, Radix Glycyrrhizae Preparata, each 12g of Radix Achyranthis Bidentatae, Herba Asari 3g.(258g altogether)

Make instructions of taking: take by weight above-mentioned medical material and mix and put into medicinal cupping, add 3 bowls of water soakings after 3 hours, with vigorous fire, boil, use slow fire instead and decoct slowly, about 30-40 minute, decocts to surplus 1 bowl of medicinal liquid, leaches medicinal liquid, preservation medicinal residues.Decoct for the 2nd time, the 3rd time and add respectively 2 bowls of water, same vigorous fire boils, and changes slow fire and decocts slowly, and about 20-30 minute, decocts to surplus half bowl of medicinal liquid, leaches medicinal liquid.The medicinal liquid decocting for three times is mixed, is divided into 2 equal portions, early, evening each decoction being taken warmly a, after clothes, flat bed rest is 30 minutes.1 dose of every day, 18 doses is a course for the treatment of.

Claims (1)

1. a Chinese medicine for the treatment of ankylosing spondylitis, is characterized in that:

Constituent is: the Rhizoma Atractylodis Macrocephalae, the Radix Paeoniae Alba, Rhizoma Cibotii, Herba Taxilli, the Radix Rehmanniae, Rhizoma Drynariae, Rhizoma Et Radix Notopterygii, Radix Angelicae Pubescentis, Radix Aconiti Lateralis Preparata, process Squama Manis, Radix Scrophulariae, the Radix Astragali, Fructus Lycii, Herba Asari, Radix Achyranthis Bidentatae, Carapax Et Plastrum Testudinis (processed), Pericarpium Citri Reticulatae, Radix Glycyrrhizae Preparata;

Component ratio is: Rhizoma Atractylodis Macrocephalae 7.6-7.7%, Radix Paeoniae Alba 5.2-5.3%, Rhizoma Cibotii 7.3-7.4%, Herba Taxilli 6.3-6.5%, Radix Rehmanniae 5.4-5.5%, Rhizoma Drynariae 5.6-5.7%, Rhizoma Et Radix Notopterygii 6.6-6.7%, Radix Angelicae Pubescentis 6.2-6.3%, Radix Aconiti Lateralis Preparata 4.8-5.0%, process Squama Manis 4.9-5.0%, Radix Scrophulariae 6.4-6.5%, Radix Astragali 6.7-6.8%, Fructus Lycii 3.9-4.0%, Herba Asari 1.5-1.6%, Radix Achyranthis Bidentatae 4.9-5.0%, Carapax Et Plastrum Testudinis (processed) 4.9-5.0%, Pericarpium Citri Reticulatae 4.9-5.0%, Radix Glycyrrhizae Preparata 4.9-5.0%.