Background technology
Yellow sand Trionyx sinensis Wiegmann is Trionyx sinensis (Wiegmann) (Classification system
trionyxSinensis) local varieties, be distributed in Guangxi, Guangdong Xijiang River area, be the distinctive Trionyx sinensis Wiegmann kind of Xijiang River Water System, be commonly called as Trionyx sinensis Wiegmann, turtle, the soft-shelled turtle, Water fish, cuckold etc.The blunt circle of yellow sand Trionyx sinensis Wiegmann Trionyx sinensis build and flat, back is light yellow, the structural arrangement decorative pattern of carapace high-visible vertebra and rib in appearance, there are 8-9 by detesting the line of rabbet joint that wrinkles in the epidermis be interrupted or uninterrupted buckling arranges that an arranged end formed in carapace both sides, afterbody shirt rim is distributed with numerous sclerosis and detests grain, fingerprint has grains of sand sense, and shirt rim is generous harder.Yellow sand Trionyx sinensis Wiegmann is all precious from head to foot, and the head of Trionyx sinensis Wiegmann, first, bone, meat, ovum, gallbladder, fat all can be used as medicine.Carnis Trionycis is claimed to have effect of invigorating the spleen and replenishing QI in " Mingyi Bielu ".Record according to Compendium of Material Medica, Carnis Trionycis has enriching yin and nourishing kidney, and heat clearing away disappears the multiple efficacies such as silt, spleen-and-stomach-invigorating, and can control night sweating due to consumptive disease, hyperactivity of YANG due to deficiency of YIN, pain in the low back and legs, prolonged illness is had loose bowels, pediatric epilepsy scared, the diseases such as women's amenorrhea, difficult labour." daily book on Chinese herbal medicine " is thought, Sanguis Trionycis external application can control nervus facialis, can a good appetite suddenly appearing in a serious disease air port thirsty, asthenia hectic fever, and can bone tuberculosis be treated.Sanguis Trionycis contains the compositions such as animal limb, keratin, iodine and vitamin D, can nourish YANG hyperactivity suppressing, enrich blood, subside a swelling, suppressing the hyperactive liver fire, can treat liver cirrhosis and hepatosplenomegaly, the treatment disease such as amenorrhea, menometrorrhagia.Fel Trionycis can control anal fistula.Ovum Trionycis can control chronic dysentery.Caput Trionycis dries to be ground into powder, and yellow wine is taken after mixing it with water, and can control proctoptosis.The fat of Trionyx sinensis Wiegmann can YIN nourishing be established the yang function, treatment poliosis.Modern science is thought, Trionyx sinensis Wiegmann is rich in the acid of VitAVitE, the former albumen of limb and multiple hydrogen base, the acid of unsaturated hydrogen base, trace element, can improve immune function of human body, enhance metabolism, strengthen the resistance against diseases of human body, have the effect of skin maintenance and slow down aging.
Yellow sand Trionyx sinensis Wiegmann delicious flavour, nutritious, there is certain medical value.Along with people's life and the raising of level of consumption, the demand of people to yellow sand Trionyx sinensis Wiegmann is more and more higher, only leans on wild yellow sand Trionyx sinensis Wiegmann resource, can not meet growing consumer need far away.Because wild resource is few, the huge market demand, has started yellow sand Trionyx sinensis Wiegmann artificial cultivation heat.Because artificial cultivation density is large, and most of professional raising farmer adopts the premix material of other Fish to feed when yellow sand Trionyx sinensis Wiegmann cultivates, and easily cause yellow sand Trionyx sinensis Wiegmann in breeding process to infect Red neck disease, this disease causes by addicted to the unicellular bacterium of Aquatic product gas and baculovirus.Cardinal symptom is: the neck neck of sick Trionyx sinensis Wiegmann is congested red and swollen, and flexible difficulty, sternite occurs erythema and festers gradually, and eyes nebulousurine, serious causing is blind, and the tip of the tongue, mouth and nose are hemorrhage.Through dissect the oral cavity of visible sick Trionyx sinensis Wiegmann, esophagus, stomach, intestinal mucosa be obvious point-like, speckle shape diffuse hemorrhage; Liver enlargement, matter is crisp frangible, and epidermis, in yellow or lark, has the focus of needle point size; Gollbladder dilation, splenomegaly.Wherein oral mucosa be diffuse hemorrhage account for 80%, hemorrhage also more common of gastrointestinal mucosa.Ill Trionyx sinensis Wiegmann bradykinesia, do not eat food, lean body mass, motion be slow, in the morning, unlucky death is shone in disembarkation mostly, and mortality rate, more than 80%, makes raiser suffer huge loss.
Raiser used chemobiotic medicine (as sym-closene, sodium dichloro cyanurate, DBDMH, chlorine dioxide etc.) in the past, some raisers also use forbidden drug (as malachite green oxalate, toxaphene, Furadan etc.), not only serious environment pollution, also endangers the healthy of people.Due to prolonged and repeated use, make pathogen create Drug resistance to medicine, and reduce curative effect.And the side effect of antibiotic street virus is comparatively large, life-time service can affect yellow sand Trionyx sinensis Wiegmann health and product quality.Chinese herbal medicine is pure natural substance, containing multiple biological effective components, has sterilization, antibacterial, antiinflammatory, not easily produces that bacterial drug resistance, low toxicity are even nontoxic, the feature such as noresidue or low-residual.Medicinal herbs treatment yellow sand red neck disease of soft in application, day by day by domestic and international expert is paid close attention to.
Summary of the invention
The object of the invention is not enough for above-mentioned prior art and a kind of Chinese medicine preparation and production method thereof of preventing and treating yellow sand red neck disease of soft are provided, this Chinese medicine preparation can not only treat yellow sand red neck disease of soft, also has the effect of sterilization, antibacterial, antiviral, antiinflammatory, heat-clearing and toxic substances removing, removing blood stasis and expelling pus, dissipating blood stasis for subsidence of swelling, regulating QI to relieve pain and enhancing immunity.And the present invention prevents and treats the Chinese medicine preparation of yellow sand red neck disease of soft through scientific compatibility, have no side effect, abundant raw materials is easy to get, and production process is simple, and cost is low, short treating period, instant effect, not easily recurs, and cure rate reaches more than 80%.
The present invention realizes by the following technical solutions:
The present invention prevents and treats the Chinese medicine preparation of yellow sand red neck disease of soft, comprises the raw material of following parts by weight:
Radix Sanguisorbae 20-30 part, Herba Plantaginis 20-30 part, Herba Portulacae 10-15 part, Herba Andrographis 5-10 part, Herba Patriniae 5-10 part, Spica Prunellae 4-8 part, Radix Asparagi 2-4 part, Bulbus Fritillariae Uninbracteatae 2-4 part.
The Chinese medicine preparation of above-described control yellow sand red neck disease of soft comprises the raw material of following parts by weight: Radix Sanguisorbae 26 parts, Herba Plantaginis 26 parts, Herba Portulacae 12 parts, Herba Andrographis 6 parts, Herba Patriniae 6 parts, Spica Prunellae 6 parts, Radix Asparagi 2 parts, Bulbus Fritillariae Uninbracteatae 2 parts.
The present invention is made up of Chinese medicinal materials such as Radix Sanguisorbae, Herba Plantaginis, Herba Portulacae, Herba Andrographis, Herba Patriniae, Spica Prunellae, Radix Asparagi and Bulbus Fritillariae Uninbracteataes, there is antibacterial, antiviral, heat-clearing and toxic substances removing, dissipating blood stasis for subsidence of swelling, effect of the effect of regulating QI to relieve pain and adjustment human body immune function, can prevent and treat white scour disease.
Each medicine active ingredient of above-described control yellow sand red neck disease of soft Chinese medicine formula is analyzed:
Radix Sanguisorbae, [another name] Matteuccia struthiopteri, mountain region melon, pig ginseng, spouting bleeding from anus grass; [latin name]
gardenBurnetRoot.for the dry root and rhizome of rosaceous plant Radix Sanguisorbae.Containing multiple tannin composition in Radix Sanguisorbae root: sanguiin, 1,2,6-tri-Galla Turcica (Galla Helepensis) acyl-β-D-Glucose, 1,2,3,6-tetra-Galla Turcica (Galla Helepensis) acyl-β-D-Glucose, 2,3,4,6-tetra-Galla Turcica (Galla Helepensis) acyl-D-Glucose, 1,2,3, the two Galla Turcica (Galla Helepensis) acyl methyl-β-D-glucopyanosides of 4,6-five Galla Turcica (Galla Helepensis) acyl-β-D-Glucose, 6-O-Galla Turcica (Galla Helepensis) acyl methyl-β-D-glucopyanoside, 6-O-etc.The active component of Radix Sanguisorbae has sterilization and bacteriostasis effect strong to Aeromonas hydrophila and baculovirus.Effectively can treat the Red neck disease that yellow sand Trionyx sinensis Wiegmann causes because of Aeromonas hydrophila.
Herba Plantaginis, [another name] wheel dish, Gaster Sus domestica dish, ash pan grass, [latin name]
plantagoasiaticaL.Plantagodepre.for the Herb of Plantaginaceae plant Herba Plantaginis and Plantago depressa Willd.Herba Plantaginis herb is liked growing containing plantagin aucubin, ursolic acid, B-sitosterol, positive 31 Herba Plantaginiss and is not had the fatty acids such as acid in the local alkane of humidity, Palmic acid B-paddy steroid acid esters, brown tamarind sterol ester, vitamin B, vitamin C and plantaglucide, protein, succinic acid, adenine, choline, catalpol, stearic acid, arachidic acid, linolenic acid, Asia.The active component of Herba Plantaginis is strong to baculovirus sterilization and bacteriostasis effect.Effectively can treat the Red neck disease that yellow sand Trionyx sinensis Wiegmann causes because of Herba Plantaginis.
Herba Portulacae, [another name] Herba Portulacae, horsepower Herba Amaranthi tricoloris, [latin name]
portulacaoleraceaL.horse Amaranthus mangostanus L. is medicine food dual purpose plant, and herb can hyoscine, and seed materials for improving vision, can make veterinary drug and pesticide; Young stem and leaf can do vegetable, sour in the mouth, also capable of using as feed.Herba Portulacae herb is containing a large amount of norepinephrine and volume potassium salt; Also containing DOPA, dopamine, betanidin, isobetanidin, Radix Betae glycoside, different Radix Betae glycoside, oxalic acid, malic acid, citric acid, glutamic acid, aspartic acid, alanine and glucose, fructose, sucrose etc.; Herb shows the reaction of alkaloid, coumarin, flavone, cardiotonic glycoside and anthracene glycoside according to another report; And containing a large amount of poly-ω 3 unsaturated fatty acids.The active component of Herba Portulacae has very strong antibacterial action, plays clearing away heat-damp and promoting diuresis, removing toxic substances and promoting subsidence of swelling, antiinflammatory, quenches the thirst, diuresis.
Herba Andrographis, [another name] Chun Lianqiuliu, Herba Andrographitis, Lan Helian, Radix Gentianae, golden Rhizoma et radix valerianae, Tremella aurantialba Bandoni et Zang hook, India's grass, Herba vallisneriae Spiralis, [latin name]
andrographispaniculata.for the herb of acanthaceous plant Herba Andrographis.Folium Andrographis is containing diterpenic lactone: dexyandrographolide and deoxyandrographolide, andrographolide and andrographolide, Neoandrographolide and neoandrographolide and homoandrographolide, panicolide; Also containing andnrographan, andrographon, phosterin, cupreol-D-Glucose glycoside etc.Herba Andrographis has eliminating inflammation and expelling toxin effect, is once applied to multi-infection disease clinically.
Herba Patriniae, [another name] Patrinia scabiosaefolia Fisch, imperial bud Herba Patriniae, Herba Patriniae; [Latin
] ThlaspiarvenseLinn.for Herba Patriniae section plant Hemerocallis citrina Baroni dragon bud, patrima villosa are with root stock and root, all herbal medicine.Herba Patriniae is containing villoside, morroniside, loganin etc.[meridian distribution of property and flavor] is cool in nature, acrid in the mouth, hardship; [function cures mainly] heat-clearing and toxic substances removing, removing blood stasis and expelling pus.For appendicitis, dysentery, enteritis, hepatitis, eye conjunctivitis, postnatal blood stasis stomachache, carbuncle furuncle.
Spica Prunellae, [another name] nine Rhizoma Paridis, ferrum color grass, large headdress flower, excellent stigma flower, Intestinum caprae seu ovis dish; [Latin]
prunellavulgaris.for labiate Spica Prunellae or the long fruit ear being preced with Spica Prunellae.Spica Prunellae is containing organic acid such as the glycoside materials such as triterpene saponin, rutin, hyperin and ursolic acid, caffeic acid, free oleanolic acid; Containing the anthocyanin, d-Camphora, d-fenchone etc. of delphinidin, cyanidin in spica.[nature and flavor] are bitter, pungent, cold, [function cures mainly] clearing away heat-fire, improving eyesight, mass dissipating and swelling eliminating.
Radix Asparagi, [another name] silk winter, sky sour jujube, the astronomical winter, Wan Zangteng, large when door root, [Latin literary fame]
asparaguscochinchinensis.for the tuber of liliaceous plant Radix Asparagi (Radix Asparagi).Radix Asparagi tuber is containing steroid saponin: Radix Asparagi furan sterol oligosaccharide glycoside Asp-IV, Asp-V, Asp-VI, Asp-VII, methyl Protodioscin, pseudo-Protodioscin, 3-O(α-L-rhamnopyranosyl (1 → 4)-β-D-glucopyranosyl)-26-O-(β-D-glucopyranosyl)-(25R)-5,20-furan steroid diene-3 β etc.[nature and flavor] sweet in the mouth; Bitter; Property Great Cold; Cough caused by dryness-heat; [function cures mainly] deficiency of YIN chronic cough; Consumption of YIN caused by febrile disease; Interior-heat is quenched one's thirst; Dryness of the intestine constipation; Laryngopharynx swelling and pain.
Bulbus Fritillariae Uninbracteatae, [another name] is diligent female; Bulbus Fritillariae Cirrhosae; [latin name]
fritillary.for the dry bulb of liliaceous plant Bulbus Fritillariae Cirrhosae, Fritillaria unibracteata, Gansu Bulbus Fritillariae Uninbracteatae, Bulbus Fritillariae cirrhosae.[nature and flavor] sweet in the mouth, hardship; Cold nature.[function cures mainly] preventing phlegm from forming and stopping coughing, heat clearing away eliminating stagnation.Cure mainly phlegm heat cough, exogenous cough, cough due to yin deficiency, the few parched throat of expectorant, the diseases such as Huang is thick, lung abscess, acute mastitis, carbuncle pyogenic infections from tumour or sore, scrofula of coughing up phlegm.Modern pharmacology experiment proves, Bulbus Fritillariae Uninbracteatae has the effects such as antitussive, blood pressure lowering, raise blood sugar.
The Chinese medicine preparation production method of described control yellow sand red neck disease of soft is: dry after Radix Sanguisorbae, Herba Plantaginis, Herba Portulacae, Herba Andrographis, Herba Patriniae, Spica Prunellae, Radix Asparagi and Bulbus Fritillariae Uninbracteatae sterilization to moisture≤5% at the constant temperature drying machine of 60 DEG C respectively, pulverize and mix in proportion after crossing 80-120 object sieve, pour in pithos and soak 15-20 minute, add 5-10 times that the water yield is medicine gross weight, be heated to 95-100 DEG C of infusion 50-60 minute, when fluid temperature is down to 30-40 DEG C, filter, the Chinese medicine preparation of yellow sand red neck disease of soft must be prevented and treated.
The Chinese medicine preparation using method that the present invention prevents and treats yellow sand red neck disease of soft is: by every 667m
2, the dark 1.5m water surface yellow sand Trionyx sinensis Wiegmann culturing pool, spill Chinese medicine preparation 20kg of the present invention.Prevention: annual 4-12 month monthly splashes 1 time.Treatment: sprinkled 1 time every 3 days, sprinkles a week continuously.
The invention has the beneficial effects as follows:
1, Chinese medicine preparation of the present invention adopts that the herbaceous plant such as Radix Sanguisorbae, Herba Plantaginis, Herba Portulacae, Herba Andrographis, Herba Patriniae, Spica Prunellae, Radix Asparagi and Bulbus Fritillariae Uninbracteatae are refining to be formed, Radix Sanguisorbae, Herba Plantaginis, Herba Portulacae, Herba Andrographis, Herba Patriniae, Spica Prunellae, Radix Asparagi and Bulbus Fritillariae Uninbracteatae have no side effect, abundant raw materials is easy to get, production process is simple, and cost is low.
2, Chinese medicine preparation of the present invention can not only treat yellow sand red neck disease of soft, also has sterilization, antibacterial, antiviral, antiinflammatory, heat-clearing and toxic substances removing, removing blood stasis and expelling pus, dissipating blood stasis for subsidence of swelling, regulating QI to relieve pain and strengthens the effect of immune function.And the present invention prevents and treats the Chinese medicine preparation of yellow sand red neck disease of soft through scientific compatibility, have no side effect, abundant raw materials is easy to get, and production process is simple, and cost is low, short treating period, instant effect, not easily recurs, and cure rate reaches more than 80%.
3, Chinese medicine preparation of the present invention does not produce drug resistance, drug residue free, and meeting safe veterinary drug, ensure the requirement of animal-derived food safety, is a kind of Chinese medicine preparation of ideal control yellow sand red neck disease of soft.