CN105250176A - Skin-protecting composition with effects of whitening and removing speckles - Google Patents
Skin-protecting composition with effects of whitening and removing speckles Download PDFInfo
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- CN105250176A CN105250176A CN201510726758.8A CN201510726758A CN105250176A CN 105250176 A CN105250176 A CN 105250176A CN 201510726758 A CN201510726758 A CN 201510726758A CN 105250176 A CN105250176 A CN 105250176A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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Abstract
The invention provides a skin-protecting composition with effects of whitening and removing speckles and a whitening and speckle-removing skin-protecting product containing the composition. The skin-protecting composition with the effects of whitening and removing the speckles is prepared from rhEGF, hamamelis virginiana extracting liquid, wax gourd peel water extract and reed rhizome water extract. In the skin-protecting product, the weight content of the skin-protecting composition with the effects of whitening and removing the speckles is 1% to 2%. According to the skin-protecting composition with the effects of whitening and removing the speckles, the hamamelis virginiana extracting liquid, the wax gourd peel water extract and the reed rhizome water extract are compounded with the rhEGF, so that the rhEGF is prevented from inactivation and the efficiency of the rhEGF is greatly improved; meanwhile, the absorption of the rhEGF also can be promoted and the loss of the rhEGF in a penetration process is reduced. The skin-protecting product added with the skin-protecting composition with the effects of whitening and removing the speckles can also promote regenerative skin cells to replace and update aged cells, the content of melanin and colored cells in the skin cells can be reduced, and the deposition of skin pigments is alleviated, so that the aims of whitening and removing the speckles are realized.
Description
Technical field
The invention belongs to cosmetic technical field, be specifically related to the skin care compositions with Whitening, spot effect.
Background technology
Epidermal growth factor (EGF) is a kind of multi-functional Growth of Cells promotive factor, there is Promote cell's growth widely active, accelerate human skin cell's speed of growth, promoting the new Growth of Cells breeding of skin, is the deciding factor affecting skin health.But with advancing age and the deterioration of environment, in human body, the content of EGF reduces gradually, causes skin health impaired.Natural EGF is extensively present in mammalian body, and its content is low, and extract difficulty large, cost is high, and people adopt rhEGF to substitute natural EGF usually.RhEGF can stimulate the various cells of outer embryo rhEGF layer and endodermal origin as cornea, epithelium etc., makes it breed.Its biological effect comprises: 1) promote that low molecular weight compound is initiatively transported in cell from extracellular, increase the nutrient substance of cell; 2) glycolysis is activated to increase respiratory metabolism, energy activating phosphatase fructokinase; 3) the outer macromolecular synthesis of irritation cell, as hyaluronic acid and glycoprotein.4) synthesis of RNA and protein is activated; 5) synthesis of DNA is promoted; 6) some materials of body are as the synthesis of fruit acid, prostaglandin to promote cell proliferation to promote.These biological effects show, rhEGF, by conducted signal, causes a series of Biochemical changes in cell, starts the gene relevant with cell division, makes akinete enter cell division phase, thus make cell proliferation.RhEGF promotes that neoplastic skin cell substitutes, upgrades senile cell, the content of melanin and coloured corpuscle in Skin Cell can be reduced, alleviate the calmness of skin pigment, the pigment situation of skin can be improved in Skin Cell level, so just can reach the object of whitening, speckle dispelling.There are the skin care item containing rhEGF in prior art, to aspects such as whitening and speckle dispelling, there is certain positive effect.Because external source rhEGF occurs Physical Loss or Damage and inactivation in the processes such as skin permeation, make the content of rhEGF in skin care item will far beyond EGF concentration several times in human body even hundreds of times just can produce a desired effect, through skin verification experimental verification, the effect that can control symptom clinically just can be reached when the concentration of rhEGF is 100 μ g/ml in skin care item, when the concentration of rhEGF is 300 more than μ g/ml, clinical symptoms just starts to take a turn for the better.In skin care item, the addition of rhEGF is too high, but inefficiency, considerably increase production cost.
Summary of the invention
The technical problem to be solved in the present invention is to provide a kind of skin care compositions with Whitening, spot effect, said composition by rhEGF and Hamamelis virginiana extracting solution, Exocarpium Benincasae water extract and Rhizoma Phragmitis water extract composite, there is significant cooperative effect, skin metabolism can be promoted, spot fading, makes skin tender, tenderly white.
Technical scheme provided by the invention is a kind of skin care compositions with Whitening, spot effect, and it is made up of rhEGF, Hamamelis virginiana extracting solution, Exocarpium Benincasae water extract and Rhizoma Phragmitis water extract.
Exocarpium Benincasae water extract is by Exocarpium Benincasae extracting in water, and be separated after extracting, vacuum concentration, is Exocarpium Benincase extract.
Further, Exocarpium Benincase extract is pulled an oar by fresh Exocarpium Benincasae, is the ratio extracting in water 1 ~ 3 time of 1:5 ~ 10, extracts 1 ~ 3h, merge extractive liquid, at every turn, filter in solid-liquid ratio, and when filtrate being concentrated into 50 DEG C, relative density is the extractum of 1.10 ~ 1.30, to obtain final product.
Rhizoma Phragmitis water extract is by Rhizoma Phragmitis extracting in water, and be separated after extracting, vacuum concentration, is Rhizoma Phragmitis extract.
Further, Rhizoma Phragmitis water extract is pulled an oar by Rhizoma Phragmitis, is the ratio extracting in water 1 ~ 3 time of 1:5 ~ 10, extracts 1 ~ 3h, merge extractive liquid, at every turn, filter in solid-liquid ratio, and when filtrate being concentrated into 50 DEG C, relative density is the extractum of 1.10 ~ 1.30, to obtain final product.
Hamamelis virginiana extracting solution, outward appearance: colourless transparent liquid; PH (10% aqueous solution): 5 ~ 6.5; Index of refraction (20 DEG C): 1.4160 ~ 1.4200; Relative density (20 DEG C): 1.03 ~ 1.036.Hamamelis virginiana extracting solution skinfeel height is pleasant fresh and clean, can supplement skin moisture in time, is easy to absorb.
With the above-mentioned total restatement of skin care compositions with Whitening, spot effect, the percentage by weight of each component is respectively: rhEGF0.01 ~ 0.05%, Hamamelis virginiana extracting solution 20 ~ 40%, Exocarpium Benincasae water extract 35 ~ 50% and Rhizoma Phragmitis water extract composition 20 ~ 30%.
The percentage by weight of said components is respectively: rhEGF0.03%, Hamamelis virginiana extracting solution 30%, Exocarpium Benincasae water extract 40% and Rhizoma Phragmitis water extract composition 29.97%.
Present invention also offers a kind of whitening and speckle dispelling skin care item, containing above-mentioned whitening and speckle dispelling skin care compositions.The weight content of described whitening and speckle dispelling skin care compositions in these skin care item is 1 ~ 2%, is preferably 1.5%.
Described whitening and speckle dispelling skin care item are whitening and spot eliminating cream or whitening and speckle dispelling emulsion.The conventional formulation of whitening and spot eliminating cream/emulsion:
Whitening and speckle dispelling skin care compositions: 1 ~ 2%;
Emulsifying agent: 0.5 ~ 10%;
Emollient: 5 ~ 40%;
Excipient thickening agent: 0.1 ~ 10%;
Wetting agent: 5 ~ 30%;
Antiseptic: convention amount;
Antioxidant: convention amount;
Deionized water: surplus.
The preparation method of described whitening and speckle dispelling skin care item is: first undertaken primary emulsifying by oil phase in whitening and speckle dispelling skin care item and aqueous phase, adjust the temperature of this emulsification system 35 ~ 40 DEG C time, add rhEGF, Hamamelis virginiana extracting solution, Exocarpium Benincasae water extract and Rhizoma Phragmitis water extract composition, system is through stirring, and further cooling is up to the standards discharging.
Compared with prior art, the present invention has following beneficial effect:
1) the peptide bond structure of Exocarpium Benincasae water extract, Rhizoma Phragmitis water extract composition is similar to rhEGF; very easily intersect between peptide bond, coil, the reaction of the space displacement such as compositions; rhEGF is surrounded by the peptide molecule key ring-type of Exocarpium Benincasae water extract and Rhizoma Phragmitis water extract composition; protect rhEGF space structure; avoid rhEGF inactivation, greatly raise the efficiency.
2) Hamamelis virginiana extracting solution, Exocarpium Benincasae water extract and Rhizoma Phragmitis water extract composition itself all have effect of whitening, speckle dispelling, greatly can improve the moisturizing moisturizing of skin care compositions, the effect of skin whitening and desalination mottle.
3) Hamamelis virginiana extracting solution, Exocarpium Benincasae water extract and Rhizoma Phragmitis water extract composition is the skin penetration enhancer be easily absorbed by the skin, rhEGF and Hamamelis virginiana extracting solution, Exocarpium Benincasae water extract and Rhizoma Phragmitis water extract form to combine and are very easily absorbed by the skin, and reduce the rhEGF loss in process of osmosis.
4) in skin care item of the present invention, the weight content of rhEGF is only 1 ~ 10 μ g/ml, well below conventional addition, conveniently consumption is applied on the face, skin metabolism can be promoted, make skin tender, tenderly white, have very strong inhibitory action to the melanic synthesis in melanoma, the color at the speckle position caused by abnormal pigment can be desalinated rapidly, prevent the chromogenesis because Exposure to Sunlight causes preferably, and the pigment that Exposure to Sunlight of disappearing causes.
Detailed description of the invention
The present invention is further elaborated for following specific embodiment, but not as a limitation of the invention.
Embodiment 1
There is the skin care compositions of Whitening, spot effect: rhEGF lyophilized powder 0.01%, Hamamelis virginiana extracting solution 40%, Exocarpium Benincasae water extract 35% and Rhizoma Phragmitis water extract composition 24.99%.
Exocarpium Benincase extract is pulled an oar by fresh Exocarpium Benincasae, is the ratio extracting in water 1 time of 1:5, extracts 1h at every turn in solid-liquid ratio, and by extracting liquid filtering, when filtrate being concentrated into 50 DEG C, relative density is the extractum of 1.10, to obtain final product.
Rhizoma Phragmitis water extract is pulled an oar by Rhizoma Phragmitis, is the ratio extracting in water 1 time of 1:5, extracts 1h at every turn in solid-liquid ratio, and by extracting liquid filtering, when filtrate being concentrated into 50 DEG C, relative density is the extractum of 1.10, to obtain final product.
Embodiment 2
There is the skin care compositions of Whitening, spot effect: rhEGF lyophilized powder 0.05%, Hamamelis virginiana extracting solution 20%, Exocarpium Benincasae water extract 50% and Rhizoma Phragmitis water extract composition 29.95%.
Exocarpium Benincase extract is pulled an oar by fresh Exocarpium Benincasae, is the ratio extracting in water 3 times of 1:10, extracts 3h, merge extractive liquid, at every turn, filter in solid-liquid ratio, and when filtrate being concentrated into 50 DEG C, relative density is the extractum of 1.30, to obtain final product.
Rhizoma Phragmitis water extract is pulled an oar by Rhizoma Phragmitis, is the ratio extracting in water 3 times of 1:10, extracts 3h, merge extractive liquid, at every turn, filter in solid-liquid ratio, and when filtrate being concentrated into 50 DEG C, relative density is the extractum of 1.30, to obtain final product.
Embodiment 3
There is the skin care compositions of Whitening, spot effect: rhEGF lyophilized powder 0.03%, Hamamelis virginiana extracting solution 30%, Exocarpium Benincasae water extract 40% and Rhizoma Phragmitis water extract composition 29.97%.
Exocarpium Benincase extract is pulled an oar by fresh Exocarpium Benincasae, is the ratio extracting in water 2 times of 1:8, extracts 2h, merge extractive liquid, at every turn, filter in solid-liquid ratio, and when filtrate being concentrated into 50 DEG C, relative density is the extractum of 1.20, to obtain final product.
Rhizoma Phragmitis water extract is pulled an oar by Rhizoma Phragmitis, is the ratio extracting in water 2 times of 1:9, extracts 1h, merge extractive liquid, at every turn, filter in solid-liquid ratio, and when filtrate being concentrated into 50 DEG C, relative density is the extractum of 1.25, to obtain final product.
Embodiment 4
The formula following (w%) of whitening and spot eliminating cream:
There is the skin care compositions (skin care compositions of embodiment 1) of Whitening, spot effect: 1.5%
Glyceryl stearate: 3%
Cetearyl alcohol: 5%
Glycerol: 10%
Propylene glycol: 10%
Hydrogenation gathers certain herbaceous plants with big flowers alkene: 5%
Ceteth-20:1%
Cocoanut oil alcohol sodium sulfovinate: 0.5%
Hydroxyethyl-cellulose: 0.7%
Antiseptic: appropriate
Essence: appropriate
Deionized water: surplus.
Preparation method:
1) in oil phase process tank, oil phase material (propylene glycol, cetearyl alcohol, glyceryl stearate, hydrogenation gather certain herbaceous plants with big flowers alkene) is dropped in still, starts agitator simultaneously, be heated to 92 ~ 98 DEG C, start agitator simultaneously, material is melted completely;
2) in aqueous phase pretreatment tank, glycerol is all dropped in still, start stirring, and hydroxyethyl-cellulose is slowly dropped in still in powder form, it is made fully to disperse, then other aqueous phases (water, ceteth-20, cocoanut oil alcohol sodium sulfovinate) are dropped in still, be heated to 92 ~ 98 DEG C, be stirred to evenly;
3) filtered oil phase suck into preheating emulsion tank in, rear suction aqueous phase, and start scraper plate stirring, rapid stirring, homogenizer (start emulsifying kettle rapid stirring and homogenizer about 10 ~ 12 minutes) with this, now emulsifying temperature in the kettle should not lower than 85 DEG C.After carrying out vacuum emulsification, insulated and stirred after 10 ~ 15 minutes, then starts chiller cooling.
4) when temperature drops to 55 ~ 60 DEG C, add essence, temperature drops to 35 ~ 40 DEG C, add rhEGF, Hamamelis virginiana extracting solution, Exocarpium Benincasae water extract and Rhizoma Phragmitis water extract composition, antiseptic, continue to stir, when temperature continues to be down to 30 DEG C, discharging after the assay was approved.
Embodiment 5
The whitening and spot eliminating cream of the present embodiment is consistent with the formula of embodiment 4 and preparation method, and the skin care compositions only with whitening effect adopts the whitening and speckle dispelling skin care compositions of embodiment 2.
Embodiment 6
The whitening and spot eliminating cream of the present embodiment is consistent with the formula of embodiment 4 and preparation method, and the skin care compositions only with Whitening, spot effect adopts the skin care compositions with Whitening, spot effect of embodiment 3.
Reference examples 1
The formula following (w%) of whitening and spot eliminating cream:
RhEGF lyophilized powder: 0.01%
Glyceryl stearate: 3%
Cetearyl alcohol: 5%
Glycerol: 10%
Propylene glycol: 10%
Hydrogenation gathers certain herbaceous plants with big flowers alkene: 5%
Ceteth-20:1%
Cocoanut oil alcohol sodium sulfovinate: 0.5%
Hydroxyethyl-cellulose: 0.7%
Antiseptic: appropriate
Essence: appropriate
Deionized water: surplus.
Its preparation method is identical with embodiment 4.
Reference examples 2
The formula following (w%) of whitening and spot eliminating cream:
RhEGF lyophilized powder: 0.01%
Hamamelis virginiana extracting solution: 0.3%
Glyceryl stearate: 3%
Cetearyl alcohol: 5%
Glycerol: 10%
Propylene glycol: 10%
Hydrogenation gathers certain herbaceous plants with big flowers alkene: 5%
Ceteth-20:1%
Cocoanut oil alcohol sodium sulfovinate: 0.5%
Hydroxyethyl-cellulose: 0.7%
Antiseptic: appropriate
Essence: appropriate
Deionized water: surplus.
Its preparation method is identical with embodiment 4.
Reference examples 3
The formula following (w%) of whitening and spot eliminating cream:
RhEGF lyophilized powder: 0.01%
Hamamelis virginiana extracting solution: 0.3%
Exocarpium Benincasae water extract: 0.5%
Glyceryl stearate: 3%
Cetearyl alcohol: 5%
Glycerol: 10%
Propylene glycol: 10%
Hydrogenation gathers certain herbaceous plants with big flowers alkene: 5%
Ceteth-20:1%
Cocoanut oil alcohol sodium sulfovinate: 0.5%
Hydroxyethyl-cellulose: 0.7%
Antiseptic: appropriate
Essence: appropriate
Deionized water: surplus.
Its preparation method is identical with embodiment 4.
Reference examples 4
The formula following (w%) of whitening and spot eliminating cream:
RhEGF lyophilized powder: 0.01%
Hamamelis virginiana extracting solution: 0.3%
Rhizoma Phragmitis water extract forms: 0.3%
Glyceryl stearate: 3%
Cetearyl alcohol: 5%
Glycerol: 10%
Propylene glycol: 10%
Hydrogenation gathers certain herbaceous plants with big flowers alkene: 5%
Ceteth-20:1%
Cocoanut oil alcohol sodium sulfovinate: 0.5%
Hydroxyethyl-cellulose: 0.7%
Antiseptic: appropriate
Essence: appropriate
Deionized water: surplus.
Its preparation method is identical with embodiment 4.
Embodiment 7
Whitening and speckle dispelling emulsion formulations following (w%):
There is the skin care compositions (the whitening and speckle dispelling skin care compositions of embodiment 2) of Whitening, spot effect: 1%
Glyceryl stearate 1.5%
Cetearyl alcohol 1%
Glycerol 10%
Propylene glycol 10%
Hydrogenation gathers certain herbaceous plants with big flowers alkene 5%
Ceteth-201%
Cocoanut oil alcohol sodium sulfovinate 0.5%
Hydroxyethyl-cellulose 0.3%
Preservative qs
Essence is appropriate
Deionized water surplus.
Preparation method:
1) in oil phase pretreatment tank, oil phase material (propylene glycol, cetearyl alcohol, glyceryl stearate, hydrogenation gather certain herbaceous plants with big flowers alkene) is dropped in still, starts agitator simultaneously, be heated to 92 ~ 98 DEG C, start agitator simultaneously, material is melted completely; In aqueous phase pretreatment tank, glycerol in formula is all dropped in still, start stirring, and hydroxyethyl-cellulose is slowly sprinkled in still in powder form, it is made fully to disperse, then unclassified stores in aqueous phase (deionized water, ceteth-20, cocoanut oil alcohol sodium sulfovinate) is dropped in still, be heated to 92 ~ 98 DEG C, be stirred to evenly;
2) filtered oil phase thing suck into preheating emulsion tank in, rear suction aqueous-phase material, and start scraper plate stirrings, rapid stirring, homogenizer (startup emulsifying kettle rapid stirring and homogenizer about 10 ~ 12 minutes) successively, now emulsifying temperature in the kettle should not lower than 85 DEG C.After carrying out vacuum emulsification, insulated and stirred after 10 ~ 15 minutes, then starts chiller cooling;
3) when temperature drops to 55 ~ 60 DEG C, add and add phase (essence), stir, when continuing to cool to 35 ~ 40 DEG C, add rhEGF, Hamamelis virginiana extracting solution, Exocarpium Benincasae water extract and Rhizoma Phragmitis water extract composition, antiseptic, stir, when continuing to be cooled to 30 DEG C, discharging after the assay was approved.
Embodiment 8
The whitening and speckle dispelling emulsion of the present embodiment is consistent with the formula of embodiment 7 and preparation method, and the consumption except the skin care compositions with Whitening, spot effect is 2%.
Experimental example 1
For verifying the effect of skin care item of the present invention in whitening and speckle dispelling, selecting 70 volunteers to carry out effectiveness experiment, adopting double-dummy design, contrast experiment, carry out contrast and investigate.70 volunteers do not limit for men and women, healthy population, and the age, 10 people one group, were divided into 7 groups at random between 22 ~ 49 years old.Be respectively experimental group 1 ~ 3, matched group 1 ~ 4.Experimental group 1 ~ 3 uses the whitening and spot eliminating cream of the embodiment of the present invention 4 ~ 6 respectively, and matched group 1 ~ 4 uses the whitening and spot eliminating cream of reference examples 1 ~ 4 respectively.The whitening and spot eliminating cream that 7 groups of early, middle and late uses are for each person every day once described, using method spreads upon face in right amount for getting, and loops gently to absorbing completely.Experimental period is 3 weeks.
Use color difference meter to often organize each experimenter measure use before and after the brightness of skin (represent by aberration meansigma methods, aberration meansigma methods is larger, show that skin is brighter), and by following standard, observe the effect of whitening and spot eliminating cream to face's freckle and speckle.
Evaluation criterion:
Effectively-speckle, freckle obviously go down;
Effective-speckle and freckle slightly go down;
Invalid-unchanged.
Evaluation result:
As seen from the above table, experimental group is better than the whitening and speckle dispelling effect of matched group.
Experimental example 2
The white-skinned face function of extract is verified by external Tyrosinase inhibition assays.In melanic forming process, tryrosinase plays a crucial role, melanin produce number have direct relation with the activity of tryrosinase, skin-whitening agents is generally by acting in dermal melanin generation, metabolic process remittance, the generation of check melanin, accelerates melanic metabolism and plays the effect of skin whitening.
The skin care compositions with Whitening, spot effect of experimental group 1 ~ 3, matched group 1 ~ 4 is made into respectively the solution of 1%, ultrasonic assistant dissolves 1h, gets supernatant for subsequent use as sample.According to following table 2 application of sample, mixing, 37 DEG C of water bath heat preservation 10min, add the TYR enzyme liquid 0.5ml that concentration is 100U/ml in C1 and T1 pipe, mixing.Make the light absorption value of reference side C1 at 475nm place with C2 after 10 minutes, make reference with T2 and survey the light absorption value of T1 at 475nm place.C1 is the control reaction system not adding sample, and C2 is the reference liquid of C1, and T1 is the reaction system adding testing sample, and T2 is the reference liquid of corresponding T1.Utilize formulae discovery sample to the suppression ratio of tryrosinase.
Suppression ratio=(the C1-T1)/C1 of tryrosinase.
| C1 | C2 | T1 | T2 | |
| TYR | 1 | 1 | 1 | 1 |
| Sample | 0 | 0 | 1 | 1 |
| Phosphate buffer | 1.5 | 2 | 0.5 | 1 |
| Suppression ratio | |
| Matched group 1 | 38％ |
| Matched group 2 | 45％ |
| Matched group 3 | 48％ |
| Matched group 4 | 50％ |
| Experimental group 1 | 90％ |
| Experimental group 2 | 91％ |
| Experimental group 3 | 93％ |
As seen from the above table, the tyrosinase inhibition rate of experimental group is obviously better than matched group.
Claims (7)
1. there is the skin care compositions of Whitening, spot effect, it is characterized in that: it is made up of rhEGF, Hamamelis virginiana extracting solution, Exocarpium Benincasae water extract and Rhizoma Phragmitis water extract.
2. the skin care compositions with Whitening, spot effect according to claim 1, it is characterized in that: with the total restatement of said composition, the percentage by weight of each component is respectively: rhEGF0.01 ~ 0.05%, Hamamelis virginiana extracting solution 20 ~ 40%, Exocarpium Benincasae water extract 35 ~ 50% and Rhizoma Phragmitis water extract composition 20 ~ 30%.
3. the skin care compositions with Whitening, spot effect according to claim 2, is characterized in that: the percentage by weight of each component is respectively: rhEGF0.03%, Hamamelis virginiana extracting solution 30%, Exocarpium Benincasae water extract 40% and Rhizoma Phragmitis water extract composition 29.97%.
4. whitening and speckle dispelling skin care item, is characterized in that: containing the skin care compositions with Whitening, spot effect according to any one of claims 1 to 3.
5. whitening and speckle dispelling skin care item according to claim 4, is characterized in that: the weight content of described whitening and speckle dispelling skin care compositions in these skin care item is 1 ~ 2%.
6. whitening and speckle dispelling skin care item according to claim 5, is characterized in that: the weight content of described whitening and speckle dispelling skin care compositions in these skin care item is 1.5%.
7. the whitening and speckle dispelling skin care item according to any one of claim 4 ~ 6, is characterized in that: it is whitening and spot eliminating cream or whitening and speckle dispelling emulsion.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510726758.8A CN105250176A (en) | 2015-10-29 | 2015-10-29 | Skin-protecting composition with effects of whitening and removing speckles |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510726758.8A CN105250176A (en) | 2015-10-29 | 2015-10-29 | Skin-protecting composition with effects of whitening and removing speckles |
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|---|---|---|---|---|
| JPH04235113A (en) * | 1991-01-09 | 1992-08-24 | Noevir Co Ltd | Skin-beautifying cosmetic |
| CN104814921A (en) * | 2015-05-13 | 2015-08-05 | 朱敏 | Acne-removing scar-lightening mask solution, manufacturing method and acne-removing scar-lightening mask |
| CN104983632A (en) * | 2015-07-09 | 2015-10-21 | 天津郁美净集团有限公司 | Plant skin care composition with moisturizing and skin elasticity improving effects and cosmetic |
-
2015
- 2015-10-29 CN CN201510726758.8A patent/CN105250176A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH04235113A (en) * | 1991-01-09 | 1992-08-24 | Noevir Co Ltd | Skin-beautifying cosmetic |
| CN104814921A (en) * | 2015-05-13 | 2015-08-05 | 朱敏 | Acne-removing scar-lightening mask solution, manufacturing method and acne-removing scar-lightening mask |
| CN104983632A (en) * | 2015-07-09 | 2015-10-21 | 天津郁美净集团有限公司 | Plant skin care composition with moisturizing and skin elasticity improving effects and cosmetic |
Non-Patent Citations (3)
| Title |
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| 王建新: "《化妆品植物原料手册》", 30 June 2009, 化学工业出版社 * |
| 金策等: "《科学健美与美容》", 31 December 1992, 海天出版社 * |
| 黄霏莉等: "《实用美容中药学》", 30 September 2001, 辽宁科学技术出版社 * |
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