CN105241890A - Capsule real-time inspection method with double detection - Google Patents
Capsule real-time inspection method with double detection Download PDFInfo
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- CN105241890A CN105241890A CN201510534422.1A CN201510534422A CN105241890A CN 105241890 A CN105241890 A CN 105241890A CN 201510534422 A CN201510534422 A CN 201510534422A CN 105241890 A CN105241890 A CN 105241890A
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- 239000002775 capsule Substances 0.000 title claims abstract description 126
- 238000001514 detection method Methods 0.000 title claims abstract description 81
- 238000007689 inspection Methods 0.000 title claims abstract description 23
- 238000000034 method Methods 0.000 title claims abstract description 18
- 230000007547 defect Effects 0.000 claims abstract description 71
- 230000007246 mechanism Effects 0.000 claims abstract description 57
- 238000012360 testing method Methods 0.000 claims abstract description 9
- 238000012545 processing Methods 0.000 claims description 60
- 230000005540 biological transmission Effects 0.000 claims description 24
- 238000003384 imaging method Methods 0.000 claims description 6
- 230000008520 organization Effects 0.000 claims description 6
- 238000007781 pre-processing Methods 0.000 claims description 3
- 230000007704 transition Effects 0.000 claims description 3
- 239000003814 drug Substances 0.000 description 10
- 229940079593 drug Drugs 0.000 description 6
- 230000002950 deficient Effects 0.000 description 4
- 238000013461 design Methods 0.000 description 4
- 230000007812 deficiency Effects 0.000 description 3
- 238000005538 encapsulation Methods 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- 230000006870 function Effects 0.000 description 3
- 230000004048 modification Effects 0.000 description 3
- 238000012986 modification Methods 0.000 description 3
- 230000008901 benefit Effects 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 230000008859 change Effects 0.000 description 1
- 239000002932 luster Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 238000011179 visual inspection Methods 0.000 description 1
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Abstract
The invention relates to a capsule real-time inspection method with double detection, which comprises the following steps: 1) providing a capsule real-time test platform with double detection, which includes a near-infrared detection mechanism, a visible light detection mechanism and a main controller, wherein the near-infrared detection mechanism and the visible light detection mechanism respectively perform defect detection to every capsule and the main controller is respectively connected to the near-infrared detection mechanism and the visible light detection mechanism for determining a capsule rejection strategy according to a defect detection result from the near-infrared detection mechanism and the visible light detection mechanism; and 2) performing inspection with the test platform. According to the method, there are two detection methods are available to detect the capsules, thereby improving reliability of capsule test.
Description
Technical field
The present invention relates to capsule detection field, particularly relate to a kind of capsule real-time inspection method adopting double check.
Background technology
Capsule is mainly used in encapsulating medicine, if finished capsule product existing defects, affects to the drug quality after encapsulation, such as, and medicine dose deficiency or medicine drug leakage etc.Therefore, in order to improve drug quality, extremely important to the defects detection of capsule in capsule manufacture process.
But, in prior art, the check system of defective capsule still adopts lamp procuratorial organ formula, namely relies on the visual inspection of testing staff, by means of the historical experience of testing staff, capsule whether existing defects is determined from color and luster and profile, not only speed is slow for the mode of this desk checking, and efficiency is low, and easily causes the undetected of underproof capsule, also can secondary pollution be caused time serious, thus the drug quality after impact encapsulation.
For this reason, the present invention proposes a kind of capsule real-time inspection method adopting double check, adopt the mode of mechanical detection to substitute original manual detection, in real time defective capsule is rejected while capsule is detected, drastically increase speed and the efficiency of capsule inspection.
Summary of the invention
In order to solve the technical matters that prior art exists, the invention provides a kind of capsule real-time inspection method adopting double check, the efficiency of detection is improved in the mode of mechanical detection, adopt near infrared detection mechanism and visible detection mechanism each capsule to carry out double defect detection, avoid undetected situation to occur, simultaneously, introduce real-time eliminating mechanism, in time defective capsule is rejected, thus saved a large amount of cost of labor, improve the drug quality of encapsulated.
According to an aspect of the present invention, provide a kind of capsule real-time inspection method adopting double check, the method comprises: 1) provide a kind of capsule real-time inspection platform adopting double check, described verifying bench comprises near infrared detection mechanism, visible detection mechanism and master controller, described near infrared detection mechanism and visible detection mechanism carry out defects detection to each capsule respectively, described master controller is connected respectively with described near infrared detection mechanism and visible detection mechanism, strategy rejected by defects detection result determination capsule based on described near infrared detection mechanism and visible detection mechanism, 2) use described verifying bench to test.
More specifically, in the capsule real-time inspection platform of described employing double check, also comprise: capsule transport sector, for transmitting each capsule one by one, portable hard drive, for prestoring predetermined number threshold value, the first presetted pixel amount threshold and the second presetted pixel amount threshold, described first presetted pixel amount threshold is not identical with described second presetted pixel amount threshold, described near infrared detection organization establishes is in capsule transport sector front upper, comprise black and white camera, the first image processing equipment and near-infrared light source, near-infrared light source is for carrying out near-infrared transmission to every capsule on capsule transport sector, black and white camera carries out imaging to obtain near infrared capsule image to the capsule of near-infrared transmission, first image processing equipment is connected with black and white camera, based near infrared capsule image, defects detection is carried out to capsule, and when defect capsule being detected, send existing defects signal, described visible detection organization establishes is at capsule transport sector rear upper, comprise color camera, the second image processing equipment and visible light source, visible light source is for carrying out visible transmission to every capsule on capsule transport sector, color camera carries out imaging to obtain visible ray capsule image to the capsule of visible transmission, second image processing equipment is connected with color camera, based on visible ray capsule image, defects detection is carried out to capsule, and when defect capsule being detected, send existing defects signal, counter, be connected respectively with described first image processing equipment and described second image processing equipment, when the existing defects signal that the existing defects signal or described second image processing equipment that receive described first image processing equipment transmission send, the count value of counter adds 1, described master controller is connected respectively with described portable hard drive, described counter, described first image processing equipment and described second image processing equipment, when the count value of counter is more than or equal to described predetermined number threshold value, sends defect and crosses multi signal, rejecting mechanism, be connected respectively with described first image processing equipment and described first image processing equipment, comprise the first solenoid valve, first actuating equipment, second solenoid valve and the second actuating equipment, after described first solenoid valve and described first actuating equipment are arranged on described near infrared detection mechanism, before described visible detection mechanism, after described second solenoid valve and described second actuating equipment are arranged on described visible detection mechanism, described first solenoid valve is when receiving the existing defects signal that described first image processing equipment sends, described first actuating equipment is driven to reject defect capsule, described second solenoid valve is when receiving the existing defects signal that described second image processing equipment sends, described second actuating equipment is driven to reject defect capsule, power-supply unit, comprise solar powered device, commercial power interface, change-over switch and electric pressure converter, described change-over switch is connected respectively with described solar powered device and described commercial power interface, line voltage size according to commercial power interface place determines whether be switched to described solar powered device to be powered by described solar powered device, described electric pressure converter is connected with described change-over switch, with the 5V voltage transitions will inputted by change-over switch for 3.3V voltage, display device, be connected respectively with described master controller and described rejecting mechanism, for receiving and showing the count value of counter that described master controller sends and defect crosses multi signal, also for receiving and showing the rejecting number of times of determined described first actuating equipment of described rejecting mechanism and the rejecting number of times of described second actuating equipment, wherein, near infrared capsule image and benchmark near-infrared image subtract each other to obtain error image by described first image processing equipment, the quantity of the pixel of pixel value non-zero in calculated difference image, when the quantity of the pixel of non-zero is more than or equal to described first presetted pixel amount threshold, send existing defects signal, otherwise, send not existing defects signal, described first image processing equipment by visible ray capsule image and visible image subtraction to obtain error image, the quantity of the pixel of pixel value non-zero in calculated difference image, when the quantity of the pixel of non-zero is more than or equal to described second presetted pixel amount threshold, send existing defects signal, otherwise, send not existing defects signal, described benchmark near-infrared image is in advance to the image that benchmark capsule is taken under near-infrared transmission, described visible image is in advance to the image that benchmark capsule is taken under visible transmission, and described benchmark near-infrared image and described visible image are all stored in advance in described portable hard drive.
More specifically, in the capsule real-time inspection platform of described employing double check: described first image processing equipment and described second image processing equipment adopt different fpga chips to realize respectively.
More specifically, in the capsule real-time inspection platform of described employing double check: described first image processing equipment and described second image processing equipment all comprise image pre-processing unit.
More specifically, in the capsule real-time inspection platform of described employing double check, described verifying bench also comprises: sound and light alarm equipment, is connected with described master controller, during for crossing multi signal in the defect receiving the transmission of described master controller, carry out corresponding sound and light alarm operation.
More specifically, in the capsule real-time inspection platform of described employing double check: described sound and light alarm equipment, described power-supply unit and described master controller are integrated on one piece of surface-mounted integrated circuit.
Accompanying drawing explanation
Below with reference to accompanying drawing, embodiment of the present invention are described, wherein:
Fig. 1 is the block diagram of the capsule real-time inspection platform of the employing double check illustrated according to an embodiment of the present invention.
Reference numeral: 1 near infrared detection mechanism; 2 visible detection mechanisms; 3 master controllers
Embodiment
Below with reference to accompanying drawings the embodiment of the capsule real-time inspection platform of employing double check of the present invention is described in detail.
The defect order of severity of capsule determines the quality of its encapsulation medicine indirectly, thus, in order to improve drug quality, and first will from overcoming defective capsule.But capsule detection means of the prior art mainly adopts manual type, inefficiency and reliability is not high.
In order to overcome above-mentioned deficiency, the present invention has built a kind of capsule real-time inspection platform adopting double check, by the double check pattern of near infrared detection and visible detection, the situation avoiding defect capsule undetected occurs, the capsule load mode of streamline and the introducing of automatic reject mechanism simultaneously, drastically increases the automatization level that capsule detects.
Fig. 1 is the block diagram of the capsule real-time inspection platform of the employing double check illustrated according to an embodiment of the present invention, described verifying bench comprises near infrared detection mechanism, visible detection mechanism and master controller, described near infrared detection mechanism and visible detection mechanism carry out defects detection to each capsule respectively, described master controller is connected respectively with described near infrared detection mechanism and visible detection mechanism, and strategy rejected by the defects detection result determination capsule based on described near infrared detection mechanism and visible detection mechanism.
Then, continue to be further detailed the concrete structure of the capsule real-time inspection platform of employing double check of the present invention.
Described verifying bench also comprises: capsule transport sector, for transmitting each capsule one by one.
Described verifying bench also comprises: portable hard drive, and for prestoring predetermined number threshold value, the first presetted pixel amount threshold and the second presetted pixel amount threshold, described first presetted pixel amount threshold is not identical with described second presetted pixel amount threshold.
Described near infrared detection organization establishes is in capsule transport sector front upper, comprise black and white camera, the first image processing equipment and near-infrared light source, near-infrared light source is for carrying out near-infrared transmission to every capsule on capsule transport sector, black and white camera carries out imaging to obtain near infrared capsule image to the capsule of near-infrared transmission, first image processing equipment is connected with black and white camera, based near infrared capsule image, defects detection is carried out to capsule, and when defect capsule being detected, send existing defects signal.
Described visible detection organization establishes is at capsule transport sector rear upper, comprise color camera, the second image processing equipment and visible light source, visible light source is for carrying out visible transmission to every capsule on capsule transport sector, color camera carries out imaging to obtain visible ray capsule image to the capsule of visible transmission, second image processing equipment is connected with color camera, based on visible ray capsule image, defects detection is carried out to capsule, and when defect capsule being detected, send existing defects signal.
Described verifying bench also comprises: counter, be connected respectively with described first image processing equipment and described second image processing equipment, when the existing defects signal that the existing defects signal or described second image processing equipment that receive described first image processing equipment transmission send, the count value of counter adds 1.
Described master controller is connected respectively with described portable hard drive, described counter, described first image processing equipment and described second image processing equipment, when the count value of counter is more than or equal to described predetermined number threshold value, sends defect and crosses multi signal.
Described verifying bench also comprises: rejecting mechanism, be connected respectively with described first image processing equipment and described first image processing equipment, comprise the first solenoid valve, first actuating equipment, second solenoid valve and the second actuating equipment, after described first solenoid valve and described first actuating equipment are arranged on described near infrared detection mechanism, before described visible detection mechanism, after described second solenoid valve and described second actuating equipment are arranged on described visible detection mechanism, described first solenoid valve is when receiving the existing defects signal that described first image processing equipment sends, described first actuating equipment is driven to reject defect capsule, described second solenoid valve is when receiving the existing defects signal that described second image processing equipment sends, described second actuating equipment is driven to reject defect capsule.
Described verifying bench also comprises: power-supply unit, comprise solar powered device, commercial power interface, change-over switch and electric pressure converter, described change-over switch is connected respectively with described solar powered device and described commercial power interface, line voltage size according to commercial power interface place determines whether be switched to described solar powered device to be powered by described solar powered device, described electric pressure converter is connected with described change-over switch, with the 5V voltage transitions will inputted by change-over switch for 3.3V voltage.
Described verifying bench also comprises: display device, be connected respectively with described master controller and described rejecting mechanism, for receiving and showing the count value of counter that described master controller sends and defect crosses multi signal, also for receiving and showing the rejecting number of times of determined described first actuating equipment of described rejecting mechanism and the rejecting number of times of described second actuating equipment.
Wherein, near infrared capsule image and benchmark near-infrared image subtract each other to obtain error image by described first image processing equipment, the quantity of the pixel of pixel value non-zero in calculated difference image, when the quantity of the pixel of non-zero is more than or equal to described first presetted pixel amount threshold, send existing defects signal, otherwise, send not existing defects signal; Described first image processing equipment by visible ray capsule image and visible image subtraction to obtain error image, the quantity of the pixel of pixel value non-zero in calculated difference image, when the quantity of the pixel of non-zero is more than or equal to described second presetted pixel amount threshold, send existing defects signal, otherwise, send not existing defects signal; Described benchmark near-infrared image is in advance to the image that benchmark capsule is taken under near-infrared transmission, described visible image is in advance to the image that benchmark capsule is taken under visible transmission, and described benchmark near-infrared image and described visible image are all stored in advance in described portable hard drive.
Alternatively, in described verifying bench: described first image processing equipment and described second image processing equipment adopt different fpga chips to realize respectively; Described first image processing equipment and described second image processing equipment all comprise image pre-processing unit; Described verifying bench also comprises: sound and light alarm equipment, is connected with described master controller, during for crossing multi signal in the defect receiving the transmission of described master controller, carries out corresponding sound and light alarm operation; And, described sound and light alarm equipment, described power-supply unit and described master controller can be integrated on one piece of surface-mounted integrated circuit.
In addition, FPGA (Field-ProgrammableGateArray), i.e. field programmable gate array, he is the product further developed on the basis of the programming devices such as PAL, GAL, CPLD.He occurs as a kind of semi-custom circuit in special IC (ASIC) field, has both solved the deficiency of custom circuit, overcomes again the shortcoming that original programming device gate circuit number is limited.
With the circuit design that hardware description language (Verilog or VHDL) completes, can through simple comprehensive and layout, being burned onto fast on FPGA and testing, is the technology main flow of modern IC designs checking.These can be edited element and can be used to realize some basic logic gates (such as AND, OR, XOR, NOT) or more more complex combination function such as demoder or mathematical equation.Inside most FPGA, in these editable elements, also comprise memory cell such as trigger (Flip-flop) or other more complete block of memory.System designer can be coupled together the logical block of FPGA inside by editable connection as required, just looks like that a breadboard has been placed in a chip.One dispatch from the factory after the logical block of finished product FPGA can change according to deviser with being connected, so FPGA can complete required logic function.
FPGA is in general slow than the speed of ASIC (special IC), realizes same function ratio ASIC circuit area and wants large.But they also have a lot of advantages such as can finished product fast, can be modified the mistake in correction program and more cheap cost.Manufacturer also may provide the FPGA of cheap still edit capability difference.Because these chips have poor can edit capability, so exploitations of these designs complete on common FPGA, then design is transferred to one and is similar on the chip of ASIC.Another method is with CPLD (ComplexProgrammableLogicDevice, CPLD).The exploitation of FPGA has a great difference relative to the exploitation of conventional P C, single-chip microcomputer.FPGA, based on concurrent operation, realizes with hardware description language; Very large difference is had compared to the sequential operation of PC or single-chip microcomputer (no matter being von Neumann structure or Harvard structure).
As far back as 1980 mid-nineties 90s, FPGA takes root in PLD equipment.CPLD and FPGA includes the Programmadle logic unit of some relatively large amount.The density of CPLD logic gate is between several thousand to several ten thousand logical blocks, and FPGA normally arrives millions of several ten thousand.The key distinction of CPLD and FPGA is their system architecture.CPLD is a somewhat restrictive structure.This structure is arranged by the logical groups of one or more editable result sum and forms with the register of the locking of some relatively small amounts.Such result lacks editor's dirigibility, but but have the time delay and logical block that can estimate to the advantage of linkage unit height ratio.And FPGA has a lot of linkage units, although allow him edit more flexibly like this, structure is complicated many.
Adopt the capsule real-time inspection platform of employing double check of the present invention, the not high and technical matters of inefficiency for capsule test mode reliability artificial in prior art, for the characteristic of capsule, introduce the double check pattern of near infrared detection and visible detection, the capsule load mode of streamline and automatic reject mechanism, thus while a large amount of cost of labor of saving, save proving time, improve checkability.
Be understandable that, although the present invention with preferred embodiment disclose as above, but above-described embodiment and be not used to limit the present invention.For any those of ordinary skill in the art, do not departing under technical solution of the present invention ambit, the technology contents of above-mentioned announcement all can be utilized to make many possible variations and modification to technical solution of the present invention, or be revised as the Equivalent embodiments of equivalent variations.Therefore, every content not departing from technical solution of the present invention, according to technical spirit of the present invention to any simple modification made for any of the above embodiments, equivalent variations and modification, all still belongs in the scope of technical solution of the present invention protection.
Claims (6)
1. adopt a capsule real-time inspection method for double check, the method comprises:
1) a kind of capsule real-time inspection platform adopting double check is provided, described verifying bench comprises near infrared detection mechanism, visible detection mechanism and master controller, described near infrared detection mechanism and visible detection mechanism carry out defects detection to each capsule respectively, described master controller is connected respectively with described near infrared detection mechanism and visible detection mechanism, and strategy rejected by the defects detection result determination capsule based on described near infrared detection mechanism and visible detection mechanism;
2) use described verifying bench to test.
2. the method for claim 1, is characterized in that, described verifying bench also comprises:
Capsule transport sector, for transmitting each capsule one by one;
Portable hard drive, for prestoring predetermined number threshold value, the first presetted pixel amount threshold and the second presetted pixel amount threshold, described first presetted pixel amount threshold is not identical with described second presetted pixel amount threshold;
Described near infrared detection organization establishes is in capsule transport sector front upper, comprise black and white camera, the first image processing equipment and near-infrared light source, near-infrared light source is for carrying out near-infrared transmission to every capsule on capsule transport sector, black and white camera carries out imaging to obtain near infrared capsule image to the capsule of near-infrared transmission, first image processing equipment is connected with black and white camera, based near infrared capsule image, defects detection is carried out to capsule, and when defect capsule being detected, send existing defects signal;
Described visible detection organization establishes is at capsule transport sector rear upper, comprise color camera, the second image processing equipment and visible light source, visible light source is for carrying out visible transmission to every capsule on capsule transport sector, color camera carries out imaging to obtain visible ray capsule image to the capsule of visible transmission, second image processing equipment is connected with color camera, based on visible ray capsule image, defects detection is carried out to capsule, and when defect capsule being detected, send existing defects signal;
Counter, be connected respectively with described first image processing equipment and described second image processing equipment, when the existing defects signal that the existing defects signal or described second image processing equipment that receive described first image processing equipment transmission send, the count value of counter adds 1;
Described master controller is connected respectively with described portable hard drive, described counter, described first image processing equipment and described second image processing equipment, when the count value of counter is more than or equal to described predetermined number threshold value, sends defect and crosses multi signal;
Rejecting mechanism, be connected respectively with described first image processing equipment and described first image processing equipment, comprise the first solenoid valve, first actuating equipment, second solenoid valve and the second actuating equipment, after described first solenoid valve and described first actuating equipment are arranged on described near infrared detection mechanism, before described visible detection mechanism, after described second solenoid valve and described second actuating equipment are arranged on described visible detection mechanism, described first solenoid valve is when receiving the existing defects signal that described first image processing equipment sends, described first actuating equipment is driven to reject defect capsule, described second solenoid valve is when receiving the existing defects signal that described second image processing equipment sends, described second actuating equipment is driven to reject defect capsule,
Power-supply unit, comprise solar powered device, commercial power interface, change-over switch and electric pressure converter, described change-over switch is connected respectively with described solar powered device and described commercial power interface, line voltage size according to commercial power interface place determines whether be switched to described solar powered device to be powered by described solar powered device, described electric pressure converter is connected with described change-over switch, with the 5V voltage transitions will inputted by change-over switch for 3.3V voltage;
Display device, be connected respectively with described master controller and described rejecting mechanism, for receiving and showing the count value of counter that described master controller sends and defect crosses multi signal, also for receiving and showing the rejecting number of times of determined described first actuating equipment of described rejecting mechanism and the rejecting number of times of described second actuating equipment;
Wherein, near infrared capsule image and benchmark near-infrared image subtract each other to obtain error image by described first image processing equipment, the quantity of the pixel of pixel value non-zero in calculated difference image, when the quantity of the pixel of non-zero is more than or equal to described first presetted pixel amount threshold, send existing defects signal, otherwise, send not existing defects signal;
Wherein, described first image processing equipment by visible ray capsule image and visible image subtraction to obtain error image, the quantity of the pixel of pixel value non-zero in calculated difference image, when the quantity of the pixel of non-zero is more than or equal to described second presetted pixel amount threshold, send existing defects signal, otherwise, send not existing defects signal;
Wherein, described benchmark near-infrared image is in advance to the image that benchmark capsule is taken under near-infrared transmission, described visible image is in advance to the image that benchmark capsule is taken under visible transmission, and described benchmark near-infrared image and described visible image are all stored in advance in described portable hard drive.
3. method as claimed in claim 2, is characterized in that: described first image processing equipment and described second image processing equipment adopt different fpga chips to realize respectively.
4. method as claimed in claim 2, is characterized in that: described first image processing equipment and described second image processing equipment all comprise image pre-processing unit.
5. method as claimed in claim 2, it is characterized in that, described verifying bench also comprises: sound and light alarm equipment, is connected with described master controller, during for crossing multi signal in the defect receiving the transmission of described master controller, carries out corresponding sound and light alarm operation.
6. method as claimed in claim 2, is characterized in that: described sound and light alarm equipment, described power-supply unit and described master controller are integrated on one piece of surface-mounted integrated circuit.
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| CN115184369A (en) * | 2022-09-14 | 2022-10-14 | 北京奥乘智能技术有限公司 | Capsule detection device, capsule detection method, image processing apparatus, and storage medium |
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| CN105241890B (en) | 2017-12-22 |
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