CN105233226A - Composition for treating rheumatic arthritis and preparation method thereof - Google Patents
Composition for treating rheumatic arthritis and preparation method thereof Download PDFInfo
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- CN105233226A CN105233226A CN201510770925.9A CN201510770925A CN105233226A CN 105233226 A CN105233226 A CN 105233226A CN 201510770925 A CN201510770925 A CN 201510770925A CN 105233226 A CN105233226 A CN 105233226A
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Abstract
The invention discloses a composition for treating rheumatic arthritis and a preparation method thereof, belongs to the technical field of traditional Chinese medicine, and aims at providing the composition capable of effectively relieving arthralgia, degrading arthrocele, recovering joint function and being small in toxic and side effect and the preparation method of the composition. According to the technical scheme, the composition is prepared from, by weight, 20-30 parts of black tea, 20-30 parts of dried ginger, 20-30 parts of poria, 20-30 parts of radix gentianae macrophyllae, 9-20 parts of ramulus mori, 10-20 parts of Chinese prickly ash, 9-18 parts of radix morindae officinalis, 5-10 parts of radix scutellariae, 4-6 parts of zaocys and 4-6 parts of herba houttuyniae.
Description
Technical field
The invention discloses a kind of compositions, specifically, be a kind of compositions for the treatment of rheumatic arthritis, belong to technical field of Chinese medicines.
Background technology
Rheumatic arthritis is a kind of common acute or chronic ICT.Rheumatic arthritis broadly should comprise rheumatoid arthritis, can recurrent exerbation involve heart.Clinical with joint and muscle migrans miserable, heavily work, pain is for feature.Belong to allergic disease, be one of main manifestations of rheumatic fever, mainly with febris acuta and arthralgia onset, it is mainly divided into following a few class:
(1) hide onset and cause the symptom of rheumatoid arthritis: about patient 60%-70% hides slow onset, and initial symptom can be general malaise, fatigue and weak, low grade fever, loss of appetite.It is sour, numb, swollen, bitterly that external bandlet rattan massage cream alleviates rheumatism.And can also preventive effect be played after having got well.There is symmetry arthralgia and moving obstacle through several weeks to the several months and accompany morning stiff.A pair arthritis not yet complete incidence graph, and there is inflammation to joint in another.These are different from the migration of rheumatic arthritis, and the latter is everlasting after an arthritic symptom disappears, another joint onset again.Amyotrophy around inflamed joint and muscle weakness unable.
(2) Acute onset causes the symptom of rheumatoid arthritis: the patient symptom of about 8% ~ 15% is similar to above-mentioned with sign, but disease progression is fast, almost occurs multiple redness and swelling of joints burning pain moving obstacle and early stage often asymmetric simultaneously.
(3) middle type onset causes the symptom of rheumatoid arthritis: about 15% ~ 20% patient's onset speed and the order of severity occupy between above-mentioned two kinds of forms, after morbidity a few days to several weeks occur joint red, swollen, hot, pain and moving obstacle, it is obvious that General Symptoms has also comparatively hidden patient.
(4) relapsing onset causes the symptom of rheumatoid arthritis: sick invades 1 ~ 2 joint just in Accute arthritis, local swelling and pain and with erythema.Disappear voluntarily after continuing a few hours to a few days, recur again, the intermission can be asymptomatic later.Repeatedly the swelling of recurrent exerbation posterior joint is not disappeared.
At present, the Therapeutic Method of rheumatic arthritis mainly contains several:
1. Drug therapy
(1) NSAID (non-steroidal anti-inflammatory drug): can suppress the synthesis of prostaglandin and produce rapidly anti-inflammatory analgesic effect, has better effects to releasing pain, but can not change the course of disease of disease.That commonly uses clinically has glucosamine hydrochloride granule, ibuprofen, penicillamine, diclofenac, aspirin, indomethacin etc.
(2) antirheumatic is acted on slowly: be used for rheumatoid arthritis and seronegative spondyloanthropathy.Certain control action is had but onset is slower to the state of an illness.Conventional has golden mixture (intramuscular injection or oral), penicillamine, sulfasalazine, chloroquine etc.
(3) cell toxicity medicament: produce immunosuppressive action by different approaches.Conventional has cyclophosphamide, methotrexate, Jin Duchun etc.They are systemic lupus erythematosus (sle), rheumatoid arthritis and vasculitic Second line Drug often, though side effect is more and comparatively serious, has very large effect more afterwards to what improve these diseases.
(4) adrenocortical hormone is antiinflammatory, Claritin, significantly improve the connective tissue diseases such as systemic lupus erythematosus (sle) more after, but these diseases can not be effected a radical cure.Its numerous side effect strengthens with dosage and the course for the treatment of extends and increases, therefore will weigh its curative effect and side effect when applying and careful in selecting.
2. surgical treatment
Comprise the displacement, synovectomy etc. of different orthomorphias, artificial joint.Operation cure diseases can not can only improve the ability of function of joint and life.
3. bone marrow transplantation
Treatment rheumatic arthritis has significant curative effect really.By recovering the autologous bone marrow transplantation method that function of immune system impels patient to fully recover, treatment child rheumatic arthritis achieves good curative effect.The concrete steps of bone marrow transplantation are: first extract patient's bone marrow with it out, by the means such as medicine and radiation, bone marrow is processed, except T cell wherein, again the bone marrow injection processed is returned in patient body, and use specific drugs to impel Bone Marrow of Patients to grow, make patients immune system's functional rehabilitation normal.Patient can be made no longer to fall ill in several years, extremely important for the child being in skeleton and growing article phase.
4. other treatment
Comprising the treatments such as physics, rehabilitation, vocational training, psychology, is the indispensable part of this class disease syndrome treatment.
Summary of the invention
For the problems referred to above, the object of the present invention is to provide one effectively can alleviate arthralgia, arthroncus of disappearing, recover function of joint and the little composition and method of making the same of toxic and side effects.
For solving the problems of the technologies described above, last technical scheme provided by the invention is such:
The compositions of this treatment rheumatic arthritis, is made up of the crude drug of following weight parts: black tea 20-30 part, Rhizoma Zingiberis 20-30 part, Poria 20-30 part, Radix Gentianae Macrophyllae 20-30 part, Ramulus Mori 9-20 part, Pericarpium Zanthoxyli 10-20 part, Radix Morindae Officinalis 9-18 part, Radix Scutellariae 5-10 part, Zaocys 4-6 part, Herba Houttuyniae 4-6 part.
The compositions of above-mentioned treatment rheumatic arthritis, is made up of the crude drug of following weight parts: black tea 22-28 part, Rhizoma Zingiberis 22-28 part, Poria 22-28 part, Radix Gentianae Macrophyllae 22-28 part, Ramulus Mori 12-18 part, Pericarpium Zanthoxyli 12-18 part, Radix Morindae Officinalis 12-16 part, Radix Scutellariae 6-9 part, Zaocys 5 parts, Herba Houttuyniae 5 parts.
Further, the compositions of above-mentioned treatment rheumatic arthritis, is made up of the crude drug of following weight parts: black tea 24-26 part, Rhizoma Zingiberis 24-26 part, Poria 24-26 part, Radix Gentianae Macrophyllae 24-26 part, Ramulus Mori 14-16 part, Pericarpium Zanthoxyli 14-16 part, Radix Morindae Officinalis 14-15 part, Radix Scutellariae 7-8 part, Zaocys 5 parts, Herba Houttuyniae 5 parts.
Last technical scheme provided by the invention is such:
1) each crude drug is taken by mass parts;
2) to step 1) Rhizoma Zingiberis that takes, Ramulus Mori, Pericarpium Zanthoxyli, Radix Scutellariae, Poria, Radix Morindae Officinalis, add 8 ~ 12 times amount soak by water 60-90min in Zaocys, decoct secondary, decocting liquid filters, secondary filtrate is merged, relative density when being evaporated to 60 DEG C is the clear paste of 1.10 ~ 1.25, obtains clear paste 1;
3) to step 1) black tea that takes, Radix Gentianae Macrophyllae, add black tea, Radix Gentianae Macrophyllae, Herba Houttuyniae gross weight 5-8 times soak by water 30-50min in Herba Houttuyniae, decoct secondary altogether, decocting liquid filters, secondary filtrate is merged, the relative density heated when being concentrated into 60 DEG C is the clear paste of 1.30 ~ 1.35, obtains clear paste 2;
4) clear paste 1 and clear paste 2 is merged.
Compared with prior art, technical scheme provided by the invention has following technological merit:
Technical scheme provided by the invention is according to arthritic etiology and pathology, and scientific compatibility, therapeutic effect is good, gentle medication, promoting flow of QI and blood dredging collateral, and have arthralgia and alleviate, arthroncus is disappeared, the combined effect that joint functional recovery takes a turn for the better, and drug effect is deeply lasting.
In prescription:
The effect catechin that polyphenol compound in black tea has antiinflammatory can be combined with single celled antibacterial, protein coagulating is precipitated, suppresses by this and eliminate pathogen, and can have the vigor suppressing to destroy osteocyte material;
The pungent evil reason knot that falls apart of Rhizoma Zingiberis, temperature can except cold ventilation, warming spleen and stomach for dispelling cold, and recuperating depleted YANG is promoted blood circulation, warming the lung to resolve fluid-retention;
Poria can dry by sharp key, and sharp key is happy Fructus Alpiniae Oxyphyllae then, leads turbid promoting the production of body fluid; Dry, dry spleen of relieving oedema or abdominal distension through diuresis or purgation, invigorating middle warmer stomach invigorating; Eradicates infantile convulsion, thick intestines and internal organs of the body, control expectorant originally, help falling of medicine;
Radix Gentianae Macrophyllae wind-damp dispelling, clearing away damp-heat, stopping numbness pain, for the contracture of muscle arteries and veins, joint is ached;
Ramulus Mori wind-damp dispelling; The meridian dredging; Row aqueous vapor.Main air pain of dampness syndrome; Apoplexy and hemiplegia; Edema foot gas; Human body pruritus due to wind pathogen.For takeing on arm, joint aches is numb;
Pericarpium Zanthoxyli warming spleen and stomach for dispelling cold, dehumidifying, pain relieving, parasite killing, separates fish raw meat poison.Control food stagnation and stop drink, trusted subordinate's cold type of pain, vomiting, oh, cough with dyspnea, anemofrigid-damp arthralgia, has loose bowels, dysentery, colic, toothache, ascariasis, enterobiasis, pudendal pruritus, skin ulcer scabies;
Radix Morindae Officinalis reinforcing the kidney and supporting YANG; Bone and muscle strengthening; Expelling wind and removing dampness;
Pyretic toxicity controlled by Radix Scutellariae, hectic fever due to YIN-deficiency, alternate attack of chill and fever, and the intestines and stomach is unfavorable, and broken heap soil or fertilizer over and around the roots gas, controls five types of stranguria, makes us a surname freely, goes to joint unhappy, yearningly antipyretic, and control hot Fu Zhong Xu pain, trusted subordinate's heavily fortified point is swollen;
Zaocys dispels the wind, dredging collateral, relieving convulsion.For rheumatoid arthritis stubborn, numbness contracture, apoplexy facial hemiparalysis, hemiplegia, tic spasm, tetanus, leprosy scabies, scrofula malignant boil.
Herba Houttuyniae heat-clearing and toxic substances removing, inducing diuresis to remove edema.
In a word, technical scheme provided by the invention has obvious antiinflammatory, detumescence, analgesic effect.
Detailed description of the invention
Be described in further detail below in conjunction with the claim of detailed description of the invention to invention; but do not make any limitation of the invention; the amendment of anyone limited number of time made within the scope of the claims in the present invention, still within claims of the present invention.
Embodiment 1
A kind of compositions for the treatment of rheumatic arthritis provided by the invention, is made up of following component: black tea 30g, Rhizoma Zingiberis 30g, Poria 20g, Radix Gentianae Macrophyllae 30g, Ramulus Mori 9g, Pericarpium Zanthoxyli 20g, Radix Morindae Officinalis 9g, Radix Scutellariae 10g, Zaocys 4g, Herba Houttuyniae 6g.
Embodiment 2
The compositions of another kind treatment rheumatic arthritis provided by the invention, is made up of following component: black tea 20g, Rhizoma Zingiberis 30g, Poria 10g, Radix Gentianae Macrophyllae 20g, Ramulus Mori 20g, Pericarpium Zanthoxyli 10g, Radix Morindae Officinalis 18g, Radix Scutellariae 5g, Zaocys 6g, Herba Houttuyniae 4g.
Embodiment 3
The compositions of another kind treatment rheumatic arthritis provided by the invention, is made up of following component: black tea 28g, Rhizoma Zingiberis 22g, Poria 28g, Radix Gentianae Macrophyllae 22g, Ramulus Mori 18g, Pericarpium Zanthoxyli 12g, Radix Morindae Officinalis 16g, Radix Scutellariae 6g, Zaocys 5g, Herba Houttuyniae 5g.
Embodiment 4
The compositions of another kind treatment rheumatic arthritis provided by the invention, is made up of following component: black tea 22g, Rhizoma Zingiberis 28g, Poria 22g, Radix Gentianae Macrophyllae 28g, Ramulus Mori 12g, Pericarpium Zanthoxyli 18g, Radix Morindae Officinalis 12g, Radix Scutellariae 9g, Zaocys 5g, Herba Houttuyniae 5g.
Embodiment 5
The compositions of another kind treatment rheumatic arthritis provided by the invention, is made up of following component: black tea 25g, Rhizoma Zingiberis 25g, Poria 25g, Radix Gentianae Macrophyllae 25g, Ramulus Mori 15g, flower 15g, Radix Morindae Officinalis 15g, Radix Scutellariae 8g, Zaocys 5g, Herba Houttuyniae 5g.
In embodiment 1 to 5, the method for the compositions of any one group for the treatment of rheumatic arthritis, comprises the steps: successively
1) each crude drug is taken;
2) to step 1) Rhizoma Zingiberis that takes, Ramulus Mori, Pericarpium Zanthoxyli, Radix Scutellariae, Poria, Radix Morindae Officinalis, add 8 ~ 12 times amount soak by water 60-90min in Zaocys, decoct secondary, decocting liquid filters, secondary filtrate is merged, relative density when being evaporated to 60 DEG C is the clear paste of 1.10 ~ 1.25, obtains clear paste 1;
3) to step 1) black tea that takes, Radix Gentianae Macrophyllae, add black tea, Radix Gentianae Macrophyllae, Herba Houttuyniae gross weight 5-8 times soak by water 30-50min in Herba Houttuyniae, decoct secondary altogether, decocting liquid filters, secondary filtrate is merged, the relative density heated when being concentrated into 60 DEG C is the clear paste of 1.30 ~ 1.35, obtains clear paste 2;
4) clear paste 1 and clear paste 2 is merged.
Conveniently use compositions provided by the invention, provide the instructions of taking of compositions provided by the invention below:
1. usage
Sooner or later each 5mL for oral administration.
2. medicine time
Per course for the treatment of is 7 days, takes medicine 2 ~ 5 courses for the treatment of, per course for the treatment of 21 days, interval.
In order to advantage of the present invention is better described, provide the model case of compositions provided by the invention below:
Case 1
Mrs Li, 38 years old, suffers from rheumatic arthritis 2 years, arthralgia, once took rheumatism tablet, temporary transient onset, but drug withdrawal increased joint pain, enlargement, after taking a course for the treatment of of compositions provided by the invention, arthroncus is micro-to disappear, pain relief, obviously subsiding a swelling in joint, fully recovers after two courses for the treatment of, without recurrence after drug withdrawal.
Case 2
Mrs Wang, 55 years old, suffers from rheumatic arthritis for many years, arthralgia, once took rheumatism tablet, temporary transient onset, but drug withdrawal increased joint pain, enlargement, after taking a course for the treatment of of compositions provided by the invention, arthroncus is micro-to disappear, pain relief, after two courses for the treatment of, obviously subside a swelling in joint, fully recover after three courses for the treatment of, without recurrence after drug withdrawal.
Case 3
Mr. Zhang, 32 years old, suffers from rheumatic arthritis 1 year, arthralgia, once rheumatism tablet was taken, temporary transient onset, but drug withdrawal increased joint pain, enlargement, after taking a course for the treatment of of compositions provided by the invention, obviously subsiding a swelling in joint, fully recovers after two courses for the treatment of, without recurrence after drug withdrawal.
Case 4
Mr. Zhang, 67 years old, suffers from rheumatic arthritis for many years, arthralgia, once took rheumatism tablet, temporary transient onset, but drug withdrawal increased joint pain, enlargement, after taking a course for the treatment of of compositions provided by the invention, arthroncus is micro-to disappear, pain relief, three the course for the treatment of posterior joint obviously subside a swelling, fully recover after 5 courses for the treatment of, after drug withdrawal without recurrence.
Claims (4)
1. treat the compositions of rheumatic arthritis for one kind, it is characterized in that, be made up of the crude drug of following weight parts: black tea 20-30 part, Rhizoma Zingiberis 20-30 part, Poria 20-30 part, Radix Gentianae Macrophyllae 20-30 part, Ramulus Mori 9-20 part, Pericarpium Zanthoxyli 10-20 part, Radix Morindae Officinalis 9-18 part, Radix Scutellariae 5-10 part, Zaocys 4-6 part, Herba Houttuyniae 4-6 part.
2. the compositions for the treatment of rheumatic arthritis according to claim 1, it is characterized in that, be made up of the crude drug of following weight parts: black tea 22-28 part, Rhizoma Zingiberis 22-28 part, Poria 22-28 part, Radix Gentianae Macrophyllae 22-28 part, Ramulus Mori 12-18 part, Pericarpium Zanthoxyli 12-18 part, Radix Morindae Officinalis 12-16 part, Radix Scutellariae 6-9 part, Zaocys 5 parts, Herba Houttuyniae 5 parts.
3. the compositions for the treatment of rheumatic arthritis according to claim 1, it is characterized in that, be made up of the crude drug of following weight parts: black tea 24-26 part, Rhizoma Zingiberis 24-26 part, Poria 24-26 part, Radix Gentianae Macrophyllae 24-26 part, Ramulus Mori 14-16 part, Pericarpium Zanthoxyli 14-16 part, Radix Morindae Officinalis 14-15 part, Radix Scutellariae 7-8 part, Zaocys 5 parts, Herba Houttuyniae 5 parts.
4. the compositions of the treatment rheumatic arthritis that preparation is according to claim 1, is characterized in that, comprise the steps: successively
1) each crude drug is taken by weight portion according to claim 1;
2) to step 1) Rhizoma Zingiberis that takes, Ramulus Mori, Pericarpium Zanthoxyli, Radix Scutellariae, Poria, Radix Morindae Officinalis, add 8-12 times amount soak by water 60-90min in Zaocys, decoct secondary, decocting liquid filters, secondary filtrate is merged, relative density when being evaporated to 60 DEG C is the clear paste of 1.10-1.25, obtains clear paste 1;
3) to step 1) black tea that takes, Radix Gentianae Macrophyllae, add black tea, Radix Gentianae Macrophyllae, Herba Houttuyniae gross weight 5-8 times soak by water 30-50min in Herba Houttuyniae, decoct secondary altogether, decocting liquid filters, secondary filtrate is merged, the relative density heated when being concentrated into 60 DEG C is the clear paste of 1.30-1.35, obtains clear paste 2;
4) clear paste 1 and clear paste 2 is merged.
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN106236933A (en) * | 2016-10-19 | 2016-12-21 | 倪文新 | A kind of external application Chinese medicine water for treating and prevent and treat rheumatism |
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CN104273260A (en) * | 2014-10-01 | 2015-01-14 | 吴冬梅 | Traditional Chinese medicine tea drink capable of cultivating nature, building body and preserving health and preparation method of traditional Chinese medicine tea drink |
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
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CN106236933A (en) * | 2016-10-19 | 2016-12-21 | 倪文新 | A kind of external application Chinese medicine water for treating and prevent and treat rheumatism |
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Application publication date: 20160113 |