CN105232844A - Ointment for treating hemorrhoids with syndrome of intestinal wind injuring collaterals - Google Patents

Ointment for treating hemorrhoids with syndrome of intestinal wind injuring collaterals Download PDF

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CN105232844A
CN105232844A CN201510693060.0A CN201510693060A CN105232844A CN 105232844 A CN105232844 A CN 105232844A CN 201510693060 A CN201510693060 A CN 201510693060A CN 105232844 A CN105232844 A CN 105232844A
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anus
administration head
radix
medicine
fructus
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孙桂芝
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Abstract

The invention discloses an ointment for treating hemorrhoids with syndrome of intestinal wind injuring collaterals. The ointment comprises a suppository body; medicine bags are arranged at two ends of the suppository body, and hemorrhoid-treating ointments are contained in the medicine bags, wherein the hemorrhoid-treating ointment contains the following medicinal active components by weight: 40-60g of fructus cannabis, 40-60g of peach kernel, 40-60g of coptis chinensis, 40-60g of fructus aurantii, 25-40g of root of three-nerved spicebush, 25-40g of pericarpium arecae, 25-40g of radix bupleuri, 25-40g of cassia twig, 25-40g of fennel, 25-40g of dried orange peel, 25-40g of sanguisorba officinalis, 25-40g of radix paeoniae rubrathe, 25-40g of dried rehamnnia root, 25-40g of parched pollen typhae, 10-20g of chingma abutilon seeds, 10-20g of bitter apricot seeds, 10-20g of perilla seeds, 10-20g of mirabilite, 10-20g of cortex dictamni, 10-20g of antelope horn, 10-20g of earthworm and 10-15g of chrysanthemum. The middle of the suppository body gradually becomes thinner; an intra-anal administration head is covered outside the medicine bag on one side of the suppository body and an extra-anal administration head is covered inside the medicine bag on the other side of the suppository body; a plurality of administration holes are integrally formed on the walls of the intra-anal administration head and the extra-anal administration head; the administration holes are communicated with the corresponding medicine bags; an expanded wing is integrally formed at the front end of the intra-anal administration head; and a soft plastic layer is arranged between the expanded wing and the outer wall of the medicine bag. The ointment disclosed by the invention is simple in proportion and convenient to use; and the ointment, for hemorrhoids with syndrome of intestinal wind injuring collaterals, is good in effect of external application and is rapid to take effect.

Description

A kind ofly treat the ZHICHUANG GAO that wind hinders intestine collateral type
Technical field
The present invention relates to technical field of Chinese medicines, particularly relate to and a kind ofly treat the ZHICHUANG GAO that wind hinders intestine collateral type.
Background technology
Hemorrhoid (being commonly called as hemorrhoid) are a kind of common diseases being positioned at anus position, and any age all can fall ill, but with age, sickness rate increases gradually.Hemorrhoid are divided into internal hemorrhoid, external hemorrhoid, mixed hemorrhoid by the difference of happening part.A jagged visible line is had anal canal pectinate line in the junction of anal canal skin and rectal mucosa.Is internal hemorrhoid more than pectinate line, the supporting structure of anus pad, venous plexus and arteriovenous anastomosis Zhi Fasheng pathological change or displacement, coating rectal mucosa, because internal sphincter shrinks, anus pad is divided into left side, forward right side, right lateral side three pieces with Y type ditch, and therefore internal hemorrhoid is common in left side, forward right side and right lateral side; Be external hemorrhoid below pectinate line, coating anal canal mucosa, can be divided into connective tissue external hemorrhoid, varicose external hemorrhoid, thrombosed external hemorrhoid; What have internal hemorrhoid and external hemorrhoid concurrently is mixed hemorrhoid, is that internal hemorrhoid is merged by venous plexus and corresponding external hemorrhoid, and namely upper and lower venous plexus is identical, and mixed hemorrhoid is deviate from outside anus, during in plum blossom-shaped, is called annular hemorrhoid, if by sphincter incarceration, and formation strangulated hemorrhoid.Ancient times advocate " heat-clearing and toxic substances removing, cooling blood and dissolving stasis to Zhiduo County in hemorrhoid." Song dynasty Dou Han minister in ancient times says in " skin infection experience pandect ": " and with all hemorrhoid, all kinds of difference ... more than half based on removing heat from blood, slowly get effect." the Yuan Dynasty Zhu Zhenheng advocate " hemorrhoid are specially based on removing heat from blood " (" danxi's experiential therapy ").Liu Yuansu calls: " burnt when rushing down three, intimately move back, gold is brought about the desired sensation and breaks through wood, the restricted then five worm not lifes of wood, hemorrhoid have more " (" interchannel medical science, hemorrhoid opinion ").Dong Yuan, son and also think there is fire, has heat.Treatment is used acupuncture and moxibusion, ledebouriellae and Gentianae Macrophyllae Decoction, pain relieving as refreshing soup etc., main with heat clearing and blood cooling, dehumidifying blood stasis dispelling.These method for the treatment of in clinical, determined curative effect.But have because of wind, wet, dry, hot and patient clinically; There is deficiency of both QI and blood, spleen, lung, to suffer from a deficiency of the kidney and patient; There is simulataneous insufficiency and excessive person.So just should treat with card in treatment, should righting, eliminating evil again.Chinese traditional treatment hemorrhoid are emphasize the principle of determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, select suitable prescriptions of Chinese medicine exactly according to the body constitution of patient and symptom.The qi-regulating Chinese medicine of the Chinese medicine (as: Radix Et Rhizoma Rhei, Radix Rehmanniae, pockmarks core etc.) that the traditional Chinese medical science improves the blood-activating and stasis-removing (as: Radix Angelicae Sinensis, Flos Carthami) of blood circulation effect by tool usually to the treatment of hemorrhoid, the heat clearing and damp drying of the clear scorching effect of tool hankers medicine (as: Cortex Phellodendri, Radix Scutellariae), the Chinese medicine (Fructus Sophorae, Radix Sanguisorbae) of tool anastalsis, tool soften and lubricate stool effect, the effect of tool promotion intestinal peristalsis promoting (as; Fructus Aurantii Immaturus, Cortex Magnoliae Officinalis) and lenitive Chinese medicine (as: Radix Paeoniae, Radix Glycyrrhizae) formed.This omnipotent side's effect is not omnipotent, if not to type, then produces little effect.
Hemorrhoid are caused a disease because being divided into several type by modern Chinese medicine: as, wind hinders intestinal network, damp invasion of lower energizer, qi depression to blood stasis, sinking of QI due to deficiency of the spleen, deficiency of YIN dryness of the intestine etc., and causing a disease because of difference, then method for making is different.Hinder the type of intestinal network for wind, color of having blood in stool is scarlet, bleeds or penetrates blood, or having pruritus ani, dryness of the mouth and throat.Red tongue, white and thin fur or BOHUANG, floating and rapid pulse.Should method for the treatment of: clearing away heat and cooling blood dispels the wind.Decoction oral is used in prior art, as: acupuncture and moxibusion.Fang Xie: with Radix Rehmanniae, Radix Angelicae Sinensis, Radix Paeoniae Rubra removing heat from blood and blood in side; Radix Scutellariae, Rhizoma Coptidis, Radix Trichosanthis clearing away heat-fire; Radix Sanguisorbae, the Fructus Sophorae can the fire of clear large intestine and cooling blood for hemostasis, are equipped with Rhizoma Cimicifugae, Radix Glycyrrhizae etc. with heat-clearing and toxic substances removing; Herba Schizonepetae expelling pathogenic wind from the body surface, cooling blood for hemostasis.All medicines share, and play the merit of clearing away heat and cooling blood altogether.But oral result is slow.In view of this technical problem, need to occur that a kind of proportioning is simple, easy to use, hinder intestine collateral type hemorrhoid for wind, external is effective fireballingly a kind ofly treats the ZHICHUANG GAO that wind hinders intestine collateral type.
Summary of the invention
Technical problem to be solved by this invention is, provides a kind of proportioning simple, easy to use, hinders intestine collateral type hemorrhoid for wind, and external is effective fireballingly a kind ofly treats the ZHICHUANG GAO that wind hinders intestine collateral type.
For solving this object, the invention discloses and a kind ofly treat the ZHICHUANG GAO that wind hinders intestine collateral type, comprise cap, the two ends of cap are provided with medicine bag, medicine bag is built with ZHICHUANG GAO, wherein, the medicine activity component of ZHICHUANG GAO according to unit of weight proportioning is: Fructus Cannabis, Semen Persicae, Rhizoma Coptidis, each 40-60g of Fructus Aurantii, the Radix Linderae, Pericarpium Arecae, Radix Bupleuri, Ramulus Cinnamomi, Fructus Foeniculi, Pericarpium Citri Reticulatae, Radix Sanguisorbae, Radix Paeoniae Rubra, the Radix Rehmanniae, each 25-40g of Pollen Tyjphae (parched), Semen Abutili, Semen Armeniacae Amarum, Fructus Perillae, Natrii Sulfas, Cortex Dictamni, Cornu Saigae Tataricae, each 10-20g of Pheretima, Flos Chrysanthemi 10-15g;
The middle part of cap is gradually thin, the outer wrap of the medicine bag of cap side has administration head in anus, anus external administration head is enclosed with in the medicine bag of the opposite side of cap, administration head in anus, integratedly on the wall of anus external administration head be provided with some dosing holes, be connected between dosing holes and corresponding medicine bag, in anus, the front end of administration head is integrated is provided with the expansion wing, launch to be provided with soft plastic layer between the wing and medicine bag outer wall, the end of anus external administration head is integrated is provided with shrouding, shrouding is ellipticity, administration head in anus, anus external administration head is rubber, administration head in anus, be adhesively fixed between anus external administration head and cap.
Further, capsule built with 10-20g ointment.
The medicine activity component of ZHICHUANG GAO according to unit of weight proportioning is: Fructus Cannabis, Semen Persicae, Rhizoma Coptidis, each 40-50g of Fructus Aurantii, the Radix Linderae, Pericarpium Arecae, Radix Bupleuri, Ramulus Cinnamomi, Fructus Foeniculi, Pericarpium Citri Reticulatae, Radix Sanguisorbae, Radix Paeoniae Rubra, the Radix Rehmanniae, each 25-30g of Pollen Tyjphae (parched), Semen Abutili, Semen Armeniacae Amarum, Fructus Perillae, Natrii Sulfas, Cortex Dictamni, Cornu Saigae Tataricae, each 10-15g of Pheretima, Flos Chrysanthemi 10-12g.
The medicine activity component of ZHICHUANG GAO according to unit of weight proportioning is: Fructus Cannabis, Semen Persicae, Rhizoma Coptidis, each 50-60g of Fructus Aurantii, the Radix Linderae, Pericarpium Arecae, Radix Bupleuri, Ramulus Cinnamomi, Fructus Foeniculi, Pericarpium Citri Reticulatae, Radix Sanguisorbae, Radix Paeoniae Rubra, the Radix Rehmanniae, each 30-40g of Pollen Tyjphae (parched), Semen Abutili, Semen Armeniacae Amarum, Fructus Perillae, Natrii Sulfas, Cortex Dictamni, Cornu Saigae Tataricae, each 15-20g of Pheretima, Flos Chrysanthemi 12-15g.
In order to better realize the object of the invention, the present invention has and discloses treatment wind and hinder the preparation method of the ZHICHUANG GAO of intestine collateral type, as follows:
A, be prepared as plaster:
By cataclasm for each active component, clean, dry, put in a hermetic container, add mass percent 75% alcoholic solution, each active component is made to infiltrate vexed bubble after 12 hours, each active component is loaded percolator, after adding mass percent 75% soak with ethanol, starts to collect percolate, collect 1000ml altogether, obtain extractum by after the 75% ethanol percolation liquid heating recovery ethanol collected; Extractum is added vegetable oil, makes extractum be dissolved in 500ml vegetable oil, the vegetable oil dissolving in medicine is heated to 70 DEG C, add mass percent 20% vitamin E ointment and stir, sterilizing, obtains plaster;
B, plaster is loaded on and wants in capsule and medicine bag, medicine bag is soft plastic product, in anus, administration head, anus external administration head are inner hollow and the ellipsoid shape rubber of one end open, medicine bag to be filled in respectively in anus in administration head and anus external administration head, in anus, the opening part of administration head, anus external administration head is adhesively fixed the both sides of cap
The shrouding of C, anus external administration head is plugged and connected with pricker; Administration head, the overall plastic sealing pack of anus external administration head in cap and anus.
Ointment of the present invention, with intestine moistening dispel the wind to medicine Fructus Cannabis, Semen Persicae, bowel relieving circulation of qi promoting be monarch drug to medicine Rhizoma Coptidis, Fructus Aurantii, break full of the medicine Radix Linderae, Pericarpium Arecae with circulation of qi promoting, conciliate deliver to medicine Radix Bupleuri, Ramulus Cinnamomi, temperature intestinal circulation of qi promoting to medicine Fructus Foeniculi, Pericarpium Citri Reticulatae, bowel relieving hemostasis to medicine Radix Sanguisorbae, Radix Paeoniae Rubra, the Radix Rehmanniae, Pollen Tyjphae (parched) are ministerial drug, with the Natrii Sulfas of the medicine Semen Abutili of intestine moistening, Semen Armeniacae Amarum, Fructus Perillae, softening the hard mass heat clearing away, the Cortex Dictamni dispeled the wind, the Cornu Saigae Tataricae of endogenous wind stopping, Pheretima are adjuvant drug, with Flos Chrysanthemi for making medicine.
Proportioning of the present invention is simple, and easy to use, hinder intestine collateral type hemorrhoid for wind, the effective speed of external is fast.When the present invention uses, after tearing plastic sealing pack, pricker is pulled up from shrouding, thrust successively along multiple dosing holes, medicine bag is punctured, then patient lies prone in bed, administration head in anus is inserted along anus place, in insertion process, due to extruding and the sphincteral extruding of hands, ointment in medicine bag is constantly flowed out along dosing holes, and, in insertion process, the expansion wing and soft plastic layer make it possess elasticity, along with the insertion of administration head in anus, the expansion wing scrapes the feces in large intestine inwall and fold, enable the ointment of administration head in anus directly contact intestinal wall as far as possible, be convenient to the administration of internal hemorrhoid on the one hand, another is conveniently also beneficial to partially absorbing of intestinal, increase blood drug level.The ointment that anus external administration head is extruded, is beneficial to the coating of external hemorrhoid.The mode of this inside and outside directly administration of the present invention, except being directly administered into focus, can also partly by intestinal absorption, therapeutic effect is good, and responding time is fast.
Accompanying drawing illustrates:
Fig. 1 is structural representation of the present invention.
Fig. 2 is Fig. 1 side-looking direction schematic diagram.
Detailed description of the invention
As Figure 1-Figure 2, Fig. 1 is structural representation of the present invention.Fig. 2 is Fig. 1 side-looking direction schematic diagram.
The present invention treats the ZHICHUANG GAO that wind hinders intestine collateral type, comprise cap 5, the two ends of cap 5 are provided with medicine bag 7, medicine bag 7 is built with ZHICHUANG GAO, wherein, the medicine activity component of ZHICHUANG GAO according to unit of weight proportioning is: Fructus Cannabis, Semen Persicae, Rhizoma Coptidis, each 40-60g of Fructus Aurantii, the Radix Linderae, Pericarpium Arecae, Radix Bupleuri, Ramulus Cinnamomi, Fructus Foeniculi, Pericarpium Citri Reticulatae, Radix Sanguisorbae, Radix Paeoniae Rubra, the Radix Rehmanniae, each 25-40g of Pollen Tyjphae (parched), Semen Abutili, Semen Armeniacae Amarum, Fructus Perillae, Natrii Sulfas, Cortex Dictamni, Cornu Saigae Tataricae, each 10-20g of Pheretima, Flos Chrysanthemi 10-15g;
The middle part of cap 5 is gradually thin, the outer wrap of the medicine bag 7 of cap 5 side to have in anus administration 3, anus external administration head 6 is enclosed with in the medicine bag 7 of the opposite side of cap 5, administration 3 in anus, integratedly on the wall of anus external administration head 6 be provided with some dosing holes 4, be connected between dosing holes 4 and corresponding medicine bag 7, in anus, integrated being provided with in the front end of administration 3 launches the wing 1, launch to be provided with soft plastic layer 2 between the wing 1 and medicine bag 7 outer wall, the end of anus external administration head 6 is integrated is provided with shrouding 8, shrouding 8 is ellipticity, administration 3 in anus, anus external administration head 6 is rubber, administration 3 in anus, be adhesively fixed between anus external administration head 6 and cap.
Further, capsule built with 10-20g ointment.
Or, the medicine activity component of ZHICHUANG GAO according to unit of weight proportioning is: Fructus Cannabis, Semen Persicae, Rhizoma Coptidis, each 40-50g of Fructus Aurantii, the Radix Linderae, Pericarpium Arecae, Radix Bupleuri, Ramulus Cinnamomi, Fructus Foeniculi, Pericarpium Citri Reticulatae, Radix Sanguisorbae, Radix Paeoniae Rubra, the Radix Rehmanniae, each 25-30g of Pollen Tyjphae (parched), Semen Abutili, Semen Armeniacae Amarum, Fructus Perillae, Natrii Sulfas, Cortex Dictamni, Cornu Saigae Tataricae, each 10-15g of Pheretima, Flos Chrysanthemi 10-12g.
Or, the medicine activity component of ZHICHUANG GAO according to unit of weight proportioning is: Fructus Cannabis, Semen Persicae, Rhizoma Coptidis, each 50-60g of Fructus Aurantii, the Radix Linderae, Pericarpium Arecae, Radix Bupleuri, Ramulus Cinnamomi, Fructus Foeniculi, Pericarpium Citri Reticulatae, Radix Sanguisorbae, Radix Paeoniae Rubra, the Radix Rehmanniae, each 30-40g of Pollen Tyjphae (parched), Semen Abutili, Semen Armeniacae Amarum, Fructus Perillae, Natrii Sulfas, Cortex Dictamni, Cornu Saigae Tataricae, each 15-20g of Pheretima, Flos Chrysanthemi 12-15g.
Treatment wind hinders the ZHICHUANG GAO of intestine collateral type, and it is characterized in that, preparation method is as follows:
A, be prepared as plaster:
By cataclasm for each active component, clean, dry, put in a hermetic container, add mass percent 75% alcoholic solution, each active component is made to infiltrate vexed bubble after 12 hours, each active component is loaded percolator, after adding mass percent 75% soak with ethanol, starts to collect percolate, collect 1000ml altogether, obtain extractum by after the 75% ethanol percolation liquid heating recovery ethanol collected; Extractum is added vegetable oil, makes extractum be dissolved in 500ml vegetable oil, the vegetable oil dissolving in medicine is heated to 70 DEG C, add mass percent 20% vitamin E ointment and stir, sterilizing, obtains plaster;
B, plaster is loaded on and wants in capsule and medicine bag, medicine bag is soft plastic product, in anus, administration head, anus external administration head are inner hollow and the ellipsoid shape rubber of one end open, medicine bag to be filled in respectively in anus in administration head and anus external administration head, in anus, the opening part of administration head, anus external administration head is adhesively fixed the both sides of cap
The shrouding of C, anus external administration head is plugged and connected with pricker; Administration head, the overall plastic sealing pack of anus external administration head in cap and anus.
Comparative test:
Modling model, gets 50 mices, and male and female are random, and within every 2 hours, use blower fan advertises 30 minutes, and repeatedly feeding, every day only pushes 20% acetic acid 0.05mL/ to mice anal, is stained with after keeping 1min with cotton swab.After this anal administration, after administration 3d, continues every 2 hours use blower fans and advertises 30 minutes, after 10d, get a mice and do rectum film-making every day.Histological indications shows: have a large amount of single-column columnar epithelium cell detachment, and the visible pus stove of mucosa is formed, and body of gland goblet cell reduces, a large amount of neutrophil infiltration and ulcer a large amount of or in blocks between body of gland.Mice anus has blood and color is scarlet, pruritus ani, therefore often rubs ground with anus, its dryness of the mouth and throat, and the left and right therefore drinking times doubles, namely after 10d, wind hinders intestinal network Establishment of mouse model.
Get 40 in 50 mouse models, be divided into four groups at random, first group uses the present invention, make the cap of the present invention of ting model, smear ointment of the present invention inside and outside anus simultaneously, be preferably (Fructus Cannabis, Semen Persicae, Rhizoma Coptidis, each 50g of Fructus Aurantii, the Radix Linderae, Pericarpium Arecae, Radix Bupleuri, Ramulus Cinnamomi, Fructus Foeniculi, Pericarpium Citri Reticulatae, Radix Sanguisorbae, Radix Paeoniae Rubra, the Radix Rehmanniae, each 30g of Pollen Tyjphae (parched), Semen Abutili, Semen Armeniacae Amarum, Fructus Perillae, Natrii Sulfas, Cortex Dictamni, Cornu Saigae Tataricae, each 15g of Pheretima, Flos Chrysanthemi 12g.By cataclasm for each active component, clean, dry, put in a hermetic container, add mass percent 75% alcoholic solution, each active component is made to infiltrate vexed bubble after 12 hours, each active component is loaded percolator, after adding mass percent 75% soak with ethanol, starts to collect percolate, collect 1000ml altogether, obtain extractum by after the 75% ethanol percolation liquid heating recovery ethanol collected; Extractum is added vegetable oil, makes extractum be dissolved in 500ml vegetable oil, the vegetable oil dissolving in medicine is heated to 70 DEG C, add mass percent 20% vitamin E ointment and stir, sterilizing, obtains plaster; )
Second group uses the general prescription of background technology: the qi-regulating Chinese medicine of the Chinese medicine (as: Radix Et Rhizoma Rhei, Radix Rehmanniae, pockmarks core etc.) that the heat clearing and damp drying of the clear scorching effect of (as: Radix Angelicae Sinensis, Flos Carthami), tool hankers medicine (as: Cortex Phellodendri, Radix Scutellariae), the Chinese medicine (Fructus Sophorae, Radix Sanguisorbae) of tool anastalsis, tool soften and lubricate stool effect, the effect of tool promotion intestinal peristalsis promoting (as; Fructus Aurantii Immaturus, Cortex Magnoliae Officinalis) and lenitive Chinese medicine (as: Radix Paeoniae, Radix Glycyrrhizae) formed.Decoct as decoction, every day feeding three times, each 5ml.
3rd group uses the general prescription of background technology: the qi-regulating Chinese medicine of the Chinese medicine (as: Radix Et Rhizoma Rhei, Radix Rehmanniae, pockmarks core etc.) that the heat clearing and damp drying of the clear scorching effect of (as: Radix Angelicae Sinensis, Flos Carthami), tool hankers medicine (as: Cortex Phellodendri, Radix Scutellariae), the Chinese medicine (Fructus Sophorae, Radix Sanguisorbae) of tool anastalsis, tool soften and lubricate stool effect, the effect of tool promotion intestinal peristalsis promoting (as; Fructus Aurantii Immaturus, Cortex Magnoliae Officinalis) and lenitive Chinese medicine (as: Radix Paeoniae, Radix Glycyrrhizae) formed.According to preparation method preparation of the present invention in ointment, smear in anus, outside anus simultaneously.
4th group uses the decoction oral in background technology, as: acupuncture and moxibusion.Fang Xie: with Radix Rehmanniae, Radix Angelicae Sinensis, Radix Paeoniae Rubra removing heat from blood and blood in side; Radix Scutellariae, Rhizoma Coptidis, Radix Trichosanthis clearing away heat-fire; Radix Sanguisorbae, the Fructus Sophorae can the fire of clear large intestine and cooling blood for hemostasis, are equipped with Rhizoma Cimicifugae, Radix Glycyrrhizae etc. with heat-clearing and toxic substances removing; Herba Schizonepetae expelling pathogenic wind from the body surface, cooling blood for hemostasis.Decoct as decoction, every day feeding three times, each 5ml.
Above-mentioned four groups of administrations are after 8 days
By upper table comparison, can find, just use direct administration for first group, the 3rd group, effective directly to medicinal medicine for focus, but the 3rd group of therapeutic effect is not enough.To first group, second group, the 3rd group these three groups are carried out blood examination discovery upon administration half an hour,
The blood of first group, second group all detects, alkaloids active component, glycoside active component, terpenoid active component, lactone active component, alcohol, aldehyde and ketone active component, organic acid active component, phenolic active components.But the numerical value of first group is between the 1/3-3/4 of second group of numerical value, that is, blood drug level is not as second group.And the blood examination of the 3rd group, only detected alkaloids active component, glycoside active component, terpenoid active component, lactone active component, alcohol, organic acid active component, and blood drug level is the 1/8-1/5 of second group of numerical value.Can infer, launch the wing and scraped by the fold of one section of rectal wall, be blocked in by feces and launch outside the wing, what improve injury and intestinal absorbs situation, and ointment of the present invention is more direct for such hemorrhoid effect.
Object lesson 1
Huang, forest ranger, often walk and rest time sitting, expose to the weather, color of having blood in stool is scarlet throughout the year, and blood of bleeding, has pruritus ani, dryness of the mouth and throat, red tongue, white and thin fur or BOHUANG, floating and rapid pulse.Use the present invention: Fructus Cannabis, Semen Persicae, Rhizoma Coptidis, each 50g of Fructus Aurantii, the Radix Linderae, Pericarpium Arecae, Radix Bupleuri, Ramulus Cinnamomi, Fructus Foeniculi, Pericarpium Citri Reticulatae, Radix Sanguisorbae, Radix Paeoniae Rubra, the Radix Rehmanniae, each 30g of Pollen Tyjphae (parched), Semen Abutili, Semen Armeniacae Amarum, Fructus Perillae, Natrii Sulfas, Cortex Dictamni, Cornu Saigae Tataricae, each 15g of Pheretima, Flos Chrysanthemi 12g.By cataclasm for each active component, clean, dry, put in a hermetic container, add mass percent 75% alcoholic solution, each active component is made to infiltrate vexed bubble after 12 hours, each active component is loaded percolator, after adding mass percent 75% soak with ethanol, starts to collect percolate, collect 1000ml altogether, obtain extractum by after the 75% ethanol percolation liquid heating recovery ethanol collected, extractum is added vegetable oil, makes extractum be dissolved in 500ml vegetable oil, the vegetable oil dissolving in medicine is heated to 70 DEG C, add mass percent 20% vitamin E ointment and stir, sterilizing, obtains plaster, during use, after tearing plastic sealing pack, pricker is pulled up from shrouding, thrust successively along multiple dosing holes, medicine bag is punctured, then patient lies prone in bed, administration head in anus is inserted along anus place, in insertion process, due to extruding and the sphincteral extruding of hands, ointment in medicine bag is constantly flowed out along dosing holes, and, in insertion process, the expansion wing and soft plastic layer make it possess elasticity, along with the insertion of administration head in anus, the expansion wing scrapes the feces in large intestine inwall and fold, enable the ointment of administration head in anus directly contact intestinal wall as far as possible, be convenient to the administration of internal hemorrhoid on the one hand, another is conveniently also beneficial to partially absorbing of intestinal, increase blood drug level.The ointment that anus external administration head is extruded, is beneficial to the coating of external hemorrhoid.
The present invention once a day, each half an hour, after being used in conjunction 8 days, replys as usual, visits, do not recur after three months.
Example 2
Grandson, pedlar, roadside stands sitting, in ground, is exposed to the weather throughout the year, and color of having blood in stool is scarlet, and blood of bleeding, has pruritus ani, dryness of the mouth and throat, red tongue, white and thin fur or BOHUANG, floating and rapid pulse.Use the present invention: Fructus Cannabis, Semen Persicae, Rhizoma Coptidis, each 45g of Fructus Aurantii, the Radix Linderae, Pericarpium Arecae, Radix Bupleuri, Ramulus Cinnamomi, Fructus Foeniculi, Pericarpium Citri Reticulatae, Radix Sanguisorbae, Radix Paeoniae Rubra, the Radix Rehmanniae, each 35g of Pollen Tyjphae (parched), Semen Abutili, Semen Armeniacae Amarum, Fructus Perillae, Natrii Sulfas, Cortex Dictamni, Cornu Saigae Tataricae, each 16g of Pheretima, Flos Chrysanthemi 12g.By cataclasm for each active component, clean, dry, put in a hermetic container, add mass percent 75% alcoholic solution, each active component is made to infiltrate vexed bubble after 12 hours, each active component is loaded percolator, after adding mass percent 75% soak with ethanol, starts to collect percolate, collect 1000ml altogether, obtain extractum by after the 75% ethanol percolation liquid heating recovery ethanol collected, extractum is added vegetable oil, makes extractum be dissolved in 500ml vegetable oil, the vegetable oil dissolving in medicine is heated to 70 DEG C, add mass percent 20% vitamin E ointment and stir, sterilizing, obtains plaster, during use, after tearing plastic sealing pack, pricker is pulled up from shrouding, thrust successively along multiple dosing holes, medicine bag is punctured, then patient lies prone in bed, administration head in anus is inserted along anus place, in insertion process, due to extruding and the sphincteral extruding of hands, ointment in medicine bag is constantly flowed out along dosing holes, and, in insertion process, the expansion wing and soft plastic layer make it possess elasticity, along with the insertion of administration head in anus, the expansion wing scrapes the feces in large intestine inwall and fold, enable the ointment of administration head in anus directly contact intestinal wall as far as possible, be convenient to the administration of internal hemorrhoid on the one hand, another is conveniently also beneficial to partially absorbing of intestinal, increase blood drug level.The ointment that anus external administration head is extruded, is beneficial to the coating of external hemorrhoid.
The present invention once a day, each half an hour, after being used in conjunction 7 days, replys as usual, visits, do not recur after three months.
Example 3
Huang, cyclist, sitting and training duration, color of having blood in stool is scarlet, and blood of bleeding, has pruritus ani, dryness of the mouth and throat, red tongue, white and thin fur or BOHUANG, floating and rapid pulse.Use the present invention: Fructus Cannabis, Semen Persicae, Rhizoma Coptidis, each 40g of Fructus Aurantii, the Radix Linderae, Pericarpium Arecae, Radix Bupleuri, Ramulus Cinnamomi, Fructus Foeniculi, Pericarpium Citri Reticulatae, Radix Sanguisorbae, Radix Paeoniae Rubra, the Radix Rehmanniae, each 25g of Pollen Tyjphae (parched), Semen Abutili, Semen Armeniacae Amarum, Fructus Perillae, Natrii Sulfas, Cortex Dictamni, Cornu Saigae Tataricae, each 10g of Pheretima, Flos Chrysanthemi 10g.By cataclasm for each active component, clean, dry, put in a hermetic container, add mass percent 75% alcoholic solution, each active component is made to infiltrate vexed bubble after 12 hours, each active component is loaded percolator, after adding mass percent 75% soak with ethanol, starts to collect percolate, collect 1000ml altogether, obtain extractum by after the 75% ethanol percolation liquid heating recovery ethanol collected, extractum is added vegetable oil, makes extractum be dissolved in 500ml vegetable oil, the vegetable oil dissolving in medicine is heated to 70 DEG C, add mass percent 20% vitamin E ointment and stir, sterilizing, obtains plaster, during use, after tearing plastic sealing pack, pricker is pulled up from shrouding, thrust successively along multiple dosing holes, medicine bag is punctured, then patient lies prone in bed, administration head in anus is inserted along anus place, in insertion process, due to extruding and the sphincteral extruding of hands, ointment in medicine bag is constantly flowed out along dosing holes, and, in insertion process, the expansion wing and soft plastic layer make it possess elasticity, along with the insertion of administration head in anus, the expansion wing scrapes the feces in large intestine inwall and fold, enable the ointment of administration head in anus directly contact intestinal wall as far as possible, be convenient to the administration of internal hemorrhoid on the one hand, another is conveniently also beneficial to partially absorbing of intestinal, increase blood drug level.The ointment that anus external administration head is extruded, is beneficial to the coating of external hemorrhoid.
The present invention once a day, each half an hour, after being used in conjunction 10 days, replys as usual, visits, recurred during second month after five months, after reusing 6 days, do not recur so far.
The plaster of object lesson 1: screen 160 routine patients in 4 hospitals, before test 1 week, carries out Continuous Observation to this crowd, record symptom and change, be divided into two groups, experimental group and matched group at random, experimental group uses embodiment 1 products obtained therefrom, and matched group takes the general prescription in background technology
Curative effect situation criterion: cure: after using this product, ulcer surface disappears, and only, defecation is normal, feels without dry mouth and tougue for blood; Effective: after taking and using this product, malaise symptoms makes moderate progress, blood only; Invalid: after using this product, malaise symptoms is unchanged.Result is as shown in table 1.
Table 1:
Group Drug categories Case load Efficiently individual quantity Healing number Invalid number Recurrence number Cure rate Total effective rate
Matched group General prescription in background technology 80 60 28 20 22 35% 80%
Experimental group The present invention 80 78 71 2 7 88.7% 97.5%
Ointment of the present invention, with intestine moistening dispel the wind to medicine Fructus Cannabis, Semen Persicae, bowel relieving circulation of qi promoting be monarch drug to medicine Rhizoma Coptidis, Fructus Aurantii, break full of the medicine Radix Linderae, Pericarpium Arecae with circulation of qi promoting, conciliate deliver to medicine Radix Bupleuri, Ramulus Cinnamomi, temperature intestinal circulation of qi promoting to medicine Fructus Foeniculi, Pericarpium Citri Reticulatae, bowel relieving hemostasis to medicine Radix Sanguisorbae, Radix Paeoniae Rubra, the Radix Rehmanniae, Pollen Tyjphae (parched) are ministerial drug, with the Natrii Sulfas of the medicine Semen Abutili of intestine moistening, Semen Armeniacae Amarum, Fructus Perillae, softening the hard mass heat clearing away, the Cortex Dictamni dispeled the wind, the Cornu Saigae Tataricae of endogenous wind stopping, Pheretima are adjuvant drug, with Flos Chrysanthemi for making medicine.
Proportioning of the present invention is simple, and easy to use, hinder intestine collateral type hemorrhoid for wind, the effective speed of external is fast.When the present invention uses, after tearing plastic sealing pack, pricker is pulled up from shrouding, thrust successively along multiple dosing holes, medicine bag is punctured, then patient lies prone in bed, administration head in anus is inserted along anus place, in insertion process, due to extruding and the sphincteral extruding of hands, ointment in medicine bag is constantly flowed out along dosing holes, and, in insertion process, the expansion wing and soft plastic layer make it possess elasticity, along with the insertion of administration head in anus, the expansion wing scrapes the feces in large intestine inwall and fold, enable the ointment of administration head in anus directly contact intestinal wall as far as possible, be convenient to the administration of internal hemorrhoid on the one hand, another is conveniently also beneficial to partially absorbing of intestinal, increase blood drug level.The ointment that anus external administration head is extruded, is beneficial to the coating of external hemorrhoid.The mode of this inside and outside directly administration of the present invention, except being directly administered into focus, can also partly by intestinal absorption, therapeutic effect is good, and responding time is fast.

Claims (4)

1. treat the ZHICHUANG GAO that wind hinders intestine collateral type for one kind, comprise cap (5), the two ends of cap (5) are provided with medicine bag (7), medicine bag (7) is built with ZHICHUANG GAO, it is characterized in that, the medicine activity component of ZHICHUANG GAO according to unit of weight proportioning is: Fructus Cannabis, Semen Persicae, Rhizoma Coptidis, each 40-60g of Fructus Aurantii, the Radix Linderae, Pericarpium Arecae, Radix Bupleuri, Ramulus Cinnamomi, Fructus Foeniculi, Pericarpium Citri Reticulatae, Radix Sanguisorbae, Radix Paeoniae Rubra, the Radix Rehmanniae, each 25-40g of Pollen Tyjphae (parched), Semen Abutili, Semen Armeniacae Amarum, Fructus Perillae, Natrii Sulfas, Cortex Dictamni, Cornu Saigae Tataricae, each 10-20g of Pheretima, Flos Chrysanthemi 10-15g;
The middle part of cap (5) is gradually thin, the outer wrap of the medicine bag (7) of cap (5) side has administration head (3) in anus, anus external administration head (6) is enclosed with in the medicine bag (7) of the opposite side of cap (5), administration head (3) in anus, integratedly on the wall of anus external administration head (6) be provided with some dosing holes (4), be connected between dosing holes (4) with corresponding medicine bag (7), in anus, integrated being provided with in the front end of administration head (3) launches the wing (1), launch to be provided with soft plastic layer (2) between the wing (1) and medicine bag (7) outer wall, the end of anus external administration head (6) is integrated is provided with shrouding (8), shrouding (8) is ellipticity, administration head (3) in anus, anus external administration head (6) is rubber, administration head (3) in anus, be adhesively fixed between anus external administration head (6) and cap.
2. treat the ZHICHUANG GAO that wind hinders intestine collateral type according to claim 1, it is characterized in that, the medicine activity component of ZHICHUANG GAO according to unit of weight proportioning is: Fructus Cannabis, Semen Persicae, Rhizoma Coptidis, each 40-50g of Fructus Aurantii, the Radix Linderae, Pericarpium Arecae, Radix Bupleuri, Ramulus Cinnamomi, Fructus Foeniculi, Pericarpium Citri Reticulatae, Radix Sanguisorbae, Radix Paeoniae Rubra, the Radix Rehmanniae, each 25-30g of Pollen Tyjphae (parched), Semen Abutili, Semen Armeniacae Amarum, Fructus Perillae, Natrii Sulfas, Cortex Dictamni, Cornu Saigae Tataricae, each 10-15g of Pheretima, Flos Chrysanthemi 10-12g.
3. treat the ZHICHUANG GAO that wind hinders intestine collateral type according to claim 1, it is characterized in that, the medicine activity component of ZHICHUANG GAO according to unit of weight proportioning is: Fructus Cannabis, Semen Persicae, Rhizoma Coptidis, each 50-60g of Fructus Aurantii, the Radix Linderae, Pericarpium Arecae, Radix Bupleuri, Ramulus Cinnamomi, Fructus Foeniculi, Pericarpium Citri Reticulatae, Radix Sanguisorbae, Radix Paeoniae Rubra, the Radix Rehmanniae, each 30-40g of Pollen Tyjphae (parched), Semen Abutili, Semen Armeniacae Amarum, Fructus Perillae, Natrii Sulfas, Cortex Dictamni, Cornu Saigae Tataricae, each 15-20g of Pheretima, Flos Chrysanthemi 12-15g.
4. hinder the ZHICHUANG GAO of intestine collateral type according to the arbitrary described treatment wind of claim 1-3, it is characterized in that, preparation method is as follows:
A, be prepared as plaster:
By cataclasm for each active component, clean, dry, put in a hermetic container, add mass percent 75% alcoholic solution, each active component is made to infiltrate vexed bubble after 12 hours, each active component is loaded percolator, after adding mass percent 75% soak with ethanol, starts to collect percolate, collect 1000ml altogether, obtain extractum by after the 75% ethanol percolation liquid heating recovery ethanol collected; Extractum is added vegetable oil, makes extractum be dissolved in 500ml vegetable oil, the vegetable oil dissolving in medicine is heated to 70 DEG C, add mass percent 20% vitamin E ointment and stir, sterilizing, obtains plaster;
B, plaster is loaded on and wants in capsule and medicine bag, medicine bag is soft plastic product, in anus, administration head, anus external administration head are inner hollow and the ellipsoid shape rubber of one end open, medicine bag to be filled in respectively in anus in administration head and anus external administration head, in anus, the opening part of administration head, anus external administration head is adhesively fixed the both sides of cap
The shrouding of C, anus external administration head is plugged and connected with pricker; Administration head, the overall plastic sealing pack of anus external administration head in cap and anus.
CN201510693060.0A 2015-10-24 2015-10-24 Ointment for treating hemorrhoids with syndrome of intestinal wind injuring collaterals Pending CN105232844A (en)

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Application publication date: 20160113