CN105213686A - A kind of qi stagnation and blood stasis type hemorrhoid treating cream - Google Patents
A kind of qi stagnation and blood stasis type hemorrhoid treating cream Download PDFInfo
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Abstract
The invention discloses a kind of qi stagnation and blood stasis type hemorrhoid treating cream, comprise cap, the two ends of cap are provided with medicine bag, medicine bag is built with ZHICHUANG GAO, wherein, the medicine activity component of ZHICHUANG GAO according to unit of weight proportioning is: Radix Rubiae, Folium Callicarpae Formosanae, Folium Artemisiae Argyi, each 40-60g of Folium Hibisci Mutabilis, Pollen Typhae, Rhizoma Chuanxiong, Olibanum, Myrrha, Herba Artemisiae Anomalae, Sanguis Draxonis, Lasiosphaera Seu Calvatia, each 25-40g of Cacumen Platycladi, Semen Cassiae, Radix Angelicae Sinensis, Fructus Mori, Semen Pruni, Radix Trichosanthis, Herba Patriniae, each 10-20g of Aloe, Flos Chrysanthemi 10-15g; The middle part of cap is gradually thin, the outer wrap of the medicine bag of cap side has administration head in anus, anus external administration head is enclosed with in the medicine bag of the opposite side of cap, in anus administration head, anus external administration head wall on be integratedly provided with some dosing holes, be connected between dosing holes and corresponding medicine bag, in anus, the front end of administration head is integrated is provided with the expansion wing, launches to be provided with soft plastic layer between the wing and medicine bag outer wall.Proportioning of the present invention is simple, and easy to use, for qi stagnation and blood stasis type hemorrhoid, the effective speed of external is fast.
Description
Technical field
The present invention relates to technical field of Chinese medicines, particularly relate to a kind of qi stagnation and blood stasis type hemorrhoid treating cream.
Background technology
Hemorrhoid (being commonly called as hemorrhoid) are a kind of common diseases being positioned at anus position, and any age all can fall ill, but with age, sickness rate increases gradually.Hemorrhoid are divided into internal hemorrhoid, external hemorrhoid, mixed hemorrhoid by the difference of happening part.A jagged visible line is had anal canal pectinate line in the junction of anal canal skin and rectal mucosa.Is internal hemorrhoid more than pectinate line, the supporting structure of anus pad, venous plexus and arteriovenous anastomosis Zhi Fasheng pathological change or displacement, coating rectal mucosa, because internal sphincter shrinks, anus pad is divided into left side, forward right side, right lateral side three pieces with Y type ditch, and therefore internal hemorrhoid is common in left side, forward right side and right lateral side; Be external hemorrhoid below pectinate line, coating anal canal mucosa, can be divided into connective tissue external hemorrhoid, varicose external hemorrhoid, thrombosed external hemorrhoid; What have internal hemorrhoid and external hemorrhoid concurrently is mixed hemorrhoid, is that internal hemorrhoid is merged by venous plexus and corresponding external hemorrhoid, and namely upper and lower venous plexus is identical, and mixed hemorrhoid is deviate from outside anus, during in plum blossom-shaped, is called annular hemorrhoid, if by sphincter incarceration, and formation strangulated hemorrhoid.Ancient times advocate " heat-clearing and toxic substances removing, cooling blood and dissolving stasis to Zhiduo County in hemorrhoid." Song dynasty Dou Han minister in ancient times says in " skin infection experience pandect ": " and with all hemorrhoid, all kinds of difference ... more than half based on removing heat from blood, slowly get effect." the Yuan Dynasty Zhu Zhenheng advocate " hemorrhoid are specially based on removing heat from blood " (" danxi's experiential therapy ").Liu Yuansu calls: " burnt when rushing down three, intimately move back, gold is brought about the desired sensation and breaks through wood, the restricted then five worm not lifes of wood, hemorrhoid have more " (" interchannel medical science, hemorrhoid opinion ").Dong Yuan, son and also think there is fire, has heat.Treatment is used acupuncture and moxibusion, ledebouriellae and Gentianae Macrophyllae Decoction, pain relieving as refreshing soup etc., main with heat clearing and blood cooling, dehumidifying blood stasis dispelling.These method for the treatment of in clinical, determined curative effect.But have because of wind, wet, dry, hot and patient clinically; There is deficiency of both QI and blood, spleen, lung, to suffer from a deficiency of the kidney and patient; There is simulataneous insufficiency and excessive person.So just should treat with card in treatment, should righting, eliminating evil again.Chinese traditional treatment hemorrhoid are emphasize the principle of determination for the treatment of based on pathogenesis obtained through differentiation of symptoms and signs, select suitable prescriptions of Chinese medicine exactly according to the body constitution of patient and symptom.The qi-regulating Chinese medicine of the Chinese medicine (as: Radix Et Rhizoma Rhei, Radix Rehmanniae, pockmarks core etc.) that the traditional Chinese medical science improves the blood-activating and stasis-removing (as: Radix Angelicae Sinensis, Flos Carthami) of blood circulation effect by tool usually to the treatment of hemorrhoid, the heat clearing and damp drying of the clear scorching effect of tool hankers medicine (as: Cortex Phellodendri, Radix Scutellariae), the Chinese medicine (Fructus Sophorae, Radix Sanguisorbae) of tool anastalsis, tool soften and lubricate stool effect, the effect of tool promotion intestinal peristalsis promoting (as; Fructus Aurantii Immaturus, Cortex Magnoliae Officinalis) and lenitive Chinese medicine (as: Radix Paeoniae, Radix Glycyrrhizae) formed.This omnipotent side's effect is not omnipotent, if not to type, then produces little effect.
Hemorrhoid are caused a disease because being divided into several type by modern Chinese medicine: as, wind hinders intestinal network, damp invasion of lower energizer, qi depression to blood stasis, sinking of QI due to deficiency of the spleen, deficiency of YIN dryness of the intestine etc., and causing a disease because of difference, then method for making is different.The patient of qi stagnation and blood stasis type hemorrhoid, the swelling of anus edge, is hiddenly shown in the purple stasis of blood, and internal hemorrhoid is deviate from, and surface is purple dark rotten to the corn, and sharp ache, anal canal tightens, constipation yellow urine.Purplish tongue or have ecchymosis, Tai Bai or Huang, stringy pulse or puckery.Method for the treatment of: regulating qi to disperse stagnation, subduing swelling and detoxicating pain relieving.Side's medicine decoction of the prior art: pain relieving is as refreshing soup.Fang Xie: with the main eliminating fire and detoxication of Radix Et Rhizoma Rhei in side, blood circulation promoting competent silt; Be aided with Cortex Phellodendri, Fructus Aurantii Immaturus heat clearing and damp drying, purging heat to relax the bowels; Spina Gleditsiae detumescence and apocenosis; Radix Angelicae Sinensis, Radix Gentianae Macrophyllae nourishing blood to expel wind; Cang Intraoperative, Radix Saposhnikoviae, Rhizoma Alismatis, Semen Arecae with expelling wind and removing dampness, sending down the abnormal ascending QI pain relieving.All medicines share, and play removing toxic substances and promoting subsidence of swelling altogether, the merit of regulating qi to disperse stagnation pain relieving.
But oral result is slow.In view of this technical problem, need to occur that a kind of proportioning is simple, easy to use, for qi stagnation and blood stasis type hemorrhoid, the effective fireballing a kind of qi stagnation and blood stasis type hemorrhoid treating cream of external.
Summary of the invention
Technical problem to be solved by this invention is, provides a kind of proportioning simple, easy to use, for qi stagnation and blood stasis type hemorrhoid, and the effective fireballing a kind of qi stagnation and blood stasis type hemorrhoid treating cream of external.
For solving this object, the invention discloses a kind of qi stagnation and blood stasis type hemorrhoid treating cream, comprise cap, the two ends of cap are provided with medicine bag, medicine bag is built with ZHICHUANG GAO, wherein, the medicine activity component of ZHICHUANG GAO according to unit of weight proportioning is: Radix Rubiae, Folium Callicarpae Formosanae, Folium Artemisiae Argyi, each 40-60g of Folium Hibisci Mutabilis, Pollen Typhae, Rhizoma Chuanxiong, Olibanum, Myrrha, Herba Artemisiae Anomalae, Sanguis Draxonis, Lasiosphaera Seu Calvatia, each 25-40g of Cacumen Platycladi, Semen Cassiae, Radix Angelicae Sinensis, Fructus Mori, Semen Pruni, Radix Trichosanthis, Herba Patriniae, each 10-20g of Aloe, Flos Chrysanthemi 10-15g;
The middle part of cap is gradually thin, the outer wrap of the medicine bag of cap side has administration head in anus, anus external administration head is enclosed with in the medicine bag of the opposite side of cap, administration head in anus, integratedly on the wall of anus external administration head be provided with some dosing holes, be connected between dosing holes and corresponding medicine bag, in anus, the front end of administration head is integrated is provided with the expansion wing, launch to be provided with soft plastic layer between the wing and medicine bag outer wall, the end of anus external administration head is integrated is provided with shrouding, shrouding is ellipticity, administration head in anus, anus external administration head is rubber, administration head in anus, be adhesively fixed between anus external administration head and cap.
Further, capsule built with 10-20g ointment.
The medicine activity component of ZHICHUANG GAO according to unit of weight proportioning is: Radix Rubiae, Folium Callicarpae Formosanae, Folium Artemisiae Argyi, each 40-50g of Folium Hibisci Mutabilis, Pollen Typhae, Rhizoma Chuanxiong, Olibanum, Myrrha, Herba Artemisiae Anomalae, Sanguis Draxonis, Lasiosphaera Seu Calvatia, each 25-30g of Cacumen Platycladi, Semen Cassiae, Radix Angelicae Sinensis, Fructus Mori, Semen Pruni, Radix Trichosanthis, Herba Patriniae, each 10-15g of Aloe, Flos Chrysanthemi 10-12g.
The medicine activity component of ZHICHUANG GAO according to unit of weight proportioning is: Radix Rubiae, Folium Callicarpae Formosanae, Folium Artemisiae Argyi, each 50-60g of Folium Hibisci Mutabilis, Pollen Typhae, Rhizoma Chuanxiong, Olibanum, Myrrha, Herba Artemisiae Anomalae, Sanguis Draxonis, Lasiosphaera Seu Calvatia, each 30-40g of Cacumen Platycladi, Semen Cassiae, Radix Angelicae Sinensis, Fructus Mori, Semen Pruni, Radix Trichosanthis, Herba Patriniae, each 15-20g of Aloe, Flos Chrysanthemi 12-15g.
In order to better realize the object of the invention, the present invention has the preparation method disclosing qi stagnation and blood stasis type hemorrhoid treating cream, as follows:
A, be prepared as plaster:
By cataclasm for each active component, clean, dry, put in a hermetic container, add mass percent 75% alcoholic solution, each active component is made to infiltrate vexed bubble after 12 hours, each active component is loaded percolator, after adding mass percent 75% soak with ethanol, starts to collect percolate, collect 1000ml altogether, obtain extractum by after the 75% ethanol percolation liquid heating recovery ethanol collected; Extractum is added vegetable oil, makes extractum be dissolved in 500ml vegetable oil, the vegetable oil dissolving in medicine is heated to 70 DEG C, add mass percent 20% vitamin E ointment and stir, sterilizing, obtains plaster;
B, plaster is loaded on and wants in capsule and medicine bag, medicine bag is soft plastic product, in anus, administration head, anus external administration head are inner hollow and the ellipsoid shape rubber of one end open, medicine bag to be filled in respectively in anus in administration head and anus external administration head, in anus, the opening part of administration head, anus external administration head is adhesively fixed the both sides of cap
The shrouding of C, anus external administration head is plugged and connected with pricker; Administration head, the overall plastic sealing pack of anus external administration head in cap and anus.
Ointment of the present invention, with the Folium Artemisiae Argyi of the Folium Callicarpae Formosanae of the Radix Rubiae of removing stasis to stop bleeding, cooling blood for hemostasis, hemostasis and pain-relieving, understand the Folium Hibisci Mutabilis of detumescence for monarch drug, with the Pollen Typhae of hemostasis, the Rhizoma Chuanxiong of pain relieving, Herba Artemisiae Anomalae, the Olibanum of reducing swelling and alleviating pain, Myrrha, the Sanguis Draxonis of granulation promoting, the Lasiosphaera Seu Calvatia of removing toxic substances hemostasis, Cacumen Platycladi is ministerial drug, with the Semen Cassiae of intestine moistening, Radix Angelicae Sinensis, Fructus Mori, Semen Pruni, and the Radix Trichosanthis of detumescence and apocenosis, Herba Patriniae, the Aloe of rushing down lower lubrication is adjuvant drug, with Flos Chrysanthemi for making medicine.
Proportioning of the present invention is simple, and easy to use, for qi stagnation and blood stasis type hemorrhoid, the effective speed of external is fast.When the present invention uses, after tearing plastic sealing pack, pricker is pulled up from shrouding, thrust successively along multiple dosing holes, medicine bag is punctured, then patient lies prone in bed, administration head in anus is inserted along anus place, in insertion process, due to extruding and the sphincteral extruding of hands, ointment in medicine bag is constantly flowed out along dosing holes, and, in insertion process, the expansion wing and soft plastic layer make it possess elasticity, along with the insertion of administration head in anus, the expansion wing scrapes the feces in large intestine inwall and fold, enable the ointment of administration head in anus directly contact intestinal wall as far as possible, be convenient to the administration of internal hemorrhoid on the one hand, another is conveniently also beneficial to partially absorbing of intestinal, increase blood drug level.The ointment that anus external administration head is extruded, is beneficial to the coating of external hemorrhoid.The mode of this inside and outside directly administration of the present invention, except being directly administered into focus, can also partly by intestinal absorption, therapeutic effect is good, and responding time is fast.
Accompanying drawing illustrates:
Fig. 1 is structural representation of the present invention.
Fig. 2 is Fig. 1 side-looking direction schematic diagram.
Detailed description of the invention
As Figure 1-Figure 2, Fig. 1 is structural representation of the present invention.Fig. 2 is Fig. 1 side-looking direction schematic diagram.
Qi stagnation and blood stasis type hemorrhoid treating cream of the present invention, comprise cap 5, the two ends of cap 5 are provided with medicine bag 7, medicine bag 7 is built with ZHICHUANG GAO, wherein, the medicine activity component of ZHICHUANG GAO according to unit of weight proportioning is: Radix Rubiae, Folium Callicarpae Formosanae, Folium Artemisiae Argyi, each 40-60g of Folium Hibisci Mutabilis, Pollen Typhae, Rhizoma Chuanxiong, Olibanum, Myrrha, Herba Artemisiae Anomalae, Sanguis Draxonis, Lasiosphaera Seu Calvatia, each 25-40g of Cacumen Platycladi, Semen Cassiae, Radix Angelicae Sinensis, Fructus Mori, Semen Pruni, Radix Trichosanthis, Herba Patriniae, each 10-20g of Aloe, Flos Chrysanthemi 10-15g;
The middle part of cap 5 is gradually thin, the outer wrap of the medicine bag 7 of cap 5 side to have in anus administration 3, anus external administration head 6 is enclosed with in the medicine bag 7 of the opposite side of cap 5, administration 3 in anus, integratedly on the wall of anus external administration head 6 be provided with some dosing holes 4, be connected between dosing holes 4 and corresponding medicine bag 7, in anus, integrated being provided with in the front end of administration 3 launches the wing 1, launch to be provided with soft plastic layer 2 between the wing 1 and medicine bag 7 outer wall, the end of anus external administration head 6 is integrated is provided with shrouding 8, shrouding 8 is ellipticity, administration 3 in anus, anus external administration head 6 is rubber, administration 3 in anus, be adhesively fixed between anus external administration head 6 and cap.
Further, capsule built with 10-20g ointment.
Or, the medicine activity component of ZHICHUANG GAO according to unit of weight proportioning is: Radix Rubiae, Folium Callicarpae Formosanae, Folium Artemisiae Argyi, each 40-50g of Folium Hibisci Mutabilis, Pollen Typhae, Rhizoma Chuanxiong, Olibanum, Myrrha, Herba Artemisiae Anomalae, Sanguis Draxonis, Lasiosphaera Seu Calvatia, each 25-30g of Cacumen Platycladi, Semen Cassiae, Radix Angelicae Sinensis, Fructus Mori, Semen Pruni, Radix Trichosanthis, Herba Patriniae, each 10-15g of Aloe, Flos Chrysanthemi 10-12g.
Or, the medicine activity component of ZHICHUANG GAO according to unit of weight proportioning is: Radix Rubiae, Folium Callicarpae Formosanae, Folium Artemisiae Argyi, each 50-60g of Folium Hibisci Mutabilis, Pollen Typhae, Rhizoma Chuanxiong, Olibanum, Myrrha, Herba Artemisiae Anomalae, Sanguis Draxonis, Lasiosphaera Seu Calvatia, each 30-40g of Cacumen Platycladi, Semen Cassiae, Radix Angelicae Sinensis, Fructus Mori, Semen Pruni, Radix Trichosanthis, Herba Patriniae, each 15-20g of Aloe, Flos Chrysanthemi 12-15g.
Qi stagnation and blood stasis type hemorrhoid treating cream, it is characterized in that, preparation method is as follows:
A, be prepared as plaster:
By cataclasm for each active component, clean, dry, put in a hermetic container, add mass percent 75% alcoholic solution, each active component is made to infiltrate vexed bubble after 12 hours, each active component is loaded percolator, after adding mass percent 75% soak with ethanol, starts to collect percolate, collect 1000ml altogether, obtain extractum by after the 75% ethanol percolation liquid heating recovery ethanol collected; Extractum is added vegetable oil, makes extractum be dissolved in 500ml vegetable oil, the vegetable oil dissolving in medicine is heated to 70 DEG C, add mass percent 20% vitamin E ointment and stir, sterilizing, obtains plaster;
B, plaster is loaded on and wants in capsule and medicine bag, medicine bag is soft plastic product, in anus, administration head, anus external administration head are inner hollow and the ellipsoid shape rubber of one end open, medicine bag to be filled in respectively in anus in administration head and anus external administration head, in anus, the opening part of administration head, anus external administration head is adhesively fixed the both sides of cap
The shrouding of C, anus external administration head is plugged and connected with pricker; Administration head, the overall plastic sealing pack of anus external administration head in cap and anus.
Comparative test:
Modling model, gets 50 mices, and male and female are random, and first 3 day every day prepared with Oleum Tiglii (Oleum Tiglii is proinflammatory agent) mixed liquor 1 part of distilled water, 4 parts of pyridines, 5 parts of ether and 10 part of 6% Oleum Tiglii diethyl ether solution.During analogue formation, leaching is inhaled the rat anal 2 minutes in 6 week age of the cotton balls insertion ether light anaesthesia of 0.16mL Oleum Tiglii mixed liquor, then take out, again domestic cat is tied mouse cage side, within every 2 hours, tie domestic cat 20 minutes, mice in mouse cage is made to be in panic states, fatigue is fled, mice anus swelling inflammation after 3 days and become silted up blue or green, and flow out exudate, after this drug withdrawal in 7 days, continues to use domestic cat to tie mouse cage and ties domestic cat 20 minutes in every 2 hours, make mice in mouse cage be in panic states, after 10 days, get a mice and do rectum film-making.Histological indications shows: have a large amount of single-column columnar epithelium cell detachment, and the visible pus stove of mucosa is formed, and body of gland goblet cell reduces, a large amount of neutrophil infiltration and ulcer a large amount of or in blocks between body of gland.Observe mice to find: the swelling of anus edge, hiddenly see the purple stasis of blood, internal hemorrhoid is deviate from, and surface is purple dark rotten to the corn, and anal canal tightens, and touches rear mice and acutely struggles, sharp ache, constipation yellow urine.Namely after 10d, qi depression to blood stasis Establishment of mouse model.
Get 40 in 50 mouse models, be divided into four groups at random, first group uses the present invention, make the cap of the present invention of ting model, smear ointment of the present invention inside and outside anus simultaneously, be preferably (Radix Rubiae, Folium Callicarpae Formosanae, Folium Artemisiae Argyi, each 50g of Folium Hibisci Mutabilis, Pollen Typhae, Rhizoma Chuanxiong, Olibanum, Myrrha, Herba Artemisiae Anomalae, Sanguis Draxonis, Lasiosphaera Seu Calvatia, each 30g of Cacumen Platycladi, Semen Cassiae, Radix Angelicae Sinensis, Fructus Mori, Semen Pruni, Radix Trichosanthis, Herba Patriniae, each 15g of Aloe, Flos Chrysanthemi 12g.By cataclasm for each active component, clean, dry, put in a hermetic container, add mass percent 75% alcoholic solution, each active component is made to infiltrate vexed bubble after 12 hours, each active component is loaded percolator, after adding mass percent 75% soak with ethanol, starts to collect percolate, collect 1000ml altogether, obtain extractum by after the 75% ethanol percolation liquid heating recovery ethanol collected; Extractum is added vegetable oil, makes extractum be dissolved in 500ml vegetable oil, the vegetable oil dissolving in medicine is heated to 70 DEG C, add mass percent 20% vitamin E ointment and stir, sterilizing, obtains plaster; )
Second group uses the general prescription of background technology: the qi-regulating Chinese medicine of the Chinese medicine (as: Radix Et Rhizoma Rhei, Radix Rehmanniae, pockmarks core etc.) that the heat clearing and damp drying of the clear scorching effect of (as: Radix Angelicae Sinensis, Flos Carthami), tool hankers medicine (as: Cortex Phellodendri, Radix Scutellariae), the Chinese medicine (Fructus Sophorae, Radix Sanguisorbae) of tool anastalsis, tool soften and lubricate stool effect, the effect of tool promotion intestinal peristalsis promoting (as; Fructus Aurantii Immaturus, Cortex Magnoliae Officinalis) and lenitive Chinese medicine (as: Radix Paeoniae, Radix Glycyrrhizae) formed.Decoct as decoction, every day feeding three times, each 5ml.
3rd group uses the general prescription of background technology: the qi-regulating Chinese medicine of the Chinese medicine (as: Radix Et Rhizoma Rhei, Radix Rehmanniae, pockmarks core etc.) that the heat clearing and damp drying of the clear scorching effect of (as: Radix Angelicae Sinensis, Flos Carthami), tool hankers medicine (as: Cortex Phellodendri, Radix Scutellariae), the Chinese medicine (Fructus Sophorae, Radix Sanguisorbae) of tool anastalsis, tool soften and lubricate stool effect, the effect of tool promotion intestinal peristalsis promoting (as; Fructus Aurantii Immaturus, Cortex Magnoliae Officinalis) and lenitive Chinese medicine (as: Radix Paeoniae, Radix Glycyrrhizae) formed.According to preparation method preparation of the present invention in ointment, smear in anus, outside anus simultaneously.
4th group uses the decoction oral in background technology, as: acupuncture and moxibusion.Fang Xie: with Radix Rehmanniae, Radix Angelicae Sinensis, Radix Paeoniae Rubra removing heat from blood and blood in side; Radix Scutellariae, Rhizoma Coptidis, Radix Trichosanthis clearing away heat-fire; Radix Sanguisorbae, the Fructus Sophorae can the fire of clear large intestine and cooling blood for hemostasis, are equipped with Rhizoma Cimicifugae, Radix Glycyrrhizae etc. with heat-clearing and toxic substances removing; Herba Schizonepetae expelling pathogenic wind from the body surface, cooling blood for hemostasis.Decoct as decoction, every day feeding three times, each 5ml.
Above-mentioned four groups of administrations are after 8 days
| group | symptom | rectum is cut into slices |
| first group | the silt of anus cause is blue or green turns red and swollen and recovery of subsiding a swelling gradually, and internal hemorrhoid retraction, heals in due to intestine erosion and ulcer face.Stool colour is dark brown. | epithelial cell, the numerical value of body of gland goblet cell is within normal range, and neutrophil is even infiltration. |
| second group | anus edge still becomes silted up green grass or young crops, and swelling, internal hemorrhoid exposes, and ulcer surface reduces to some extent.Stool colour is yellow. | mucosa is rotten to the corn as seen, and goblet cell reduces, and a large amount of neutrophil infiltration, intercellular substance comes off. |
| 3rd group | slightly swelling, but still it is blue or green to become silted up, ulcer surface does not heal.Stool colour is dark brown. | accidental neutrophil infiltration between body of gland, Interstitial edema, goblet cell reduces, and ulcer is few. |
| 4th group | anus edge still becomes silted up green grass or young crops, does not heal in due to intestine erosion and ulcer face.Stool colour is yellow. | mucosa is rotten to the corn as seen, and goblet cell reduces, and a large amount of neutrophil infiltration, intercellular substance comes off. |
By upper table comparison, can find, just use direct administration for first group, the 3rd group, effective directly to medicinal medicine for focus, but the 3rd group of therapeutic effect is not enough.To first group, second group, the 3rd group these three groups are carried out blood examination discovery upon administration half an hour,
The blood of first group, second group all detects, alkaloids active component, glycoside active component, terpenoid active component, lactone active component, alcohol, aldehyde and ketone active component, organic acid active component, phenolic active components.But the numerical value of first group is between the 1/2-3/4 of second group of numerical value, that is, blood drug level is not as second group.And the blood examination of the 3rd group, only detected alkaloids active component, glycoside active component, terpenoid active component, lactone active component, alcohol, organic acid active component, and blood drug level is the 1/8-1/5 of second group of numerical value.Can infer, launch the wing and scraped by the fold of one section of rectal wall, be blocked in by feces and launch outside the wing, what improve injury and intestinal absorbs situation, and ointment of the present invention is more direct for such hemorrhoid effect.
Object lesson 1
Side certain, family's fusion, feels depressed and causes qi depression to blood stasis, and hemorrhoid recur, the swelling of anus edge and the purple stasis of blood, and internal hemorrhoid is deviate from, and surface is purple dark rotten to the corn, and sharp ache, anal canal tightens, constipation yellow urine, purplish tongue tongue the lung-pulse string.Use the present invention: Radix Rubiae, Folium Callicarpae Formosanae, Folium Artemisiae Argyi, each 50g of Folium Hibisci Mutabilis, Pollen Typhae, Rhizoma Chuanxiong, Olibanum, Myrrha, Herba Artemisiae Anomalae, Sanguis Draxonis, Lasiosphaera Seu Calvatia, each 30g of Cacumen Platycladi, Semen Cassiae, Radix Angelicae Sinensis, Fructus Mori, Semen Pruni, Radix Trichosanthis, Herba Patriniae, each 15g of Aloe, Flos Chrysanthemi 12g.By cataclasm for each active component, clean, dry, put in a hermetic container, add mass percent 75% alcoholic solution, each active component is made to infiltrate vexed bubble after 12 hours, each active component is loaded percolator, after adding mass percent 75% soak with ethanol, starts to collect percolate, collect 1000ml altogether, obtain extractum by after the 75% ethanol percolation liquid heating recovery ethanol collected, extractum is added vegetable oil, makes extractum be dissolved in 500ml vegetable oil, the vegetable oil dissolving in medicine is heated to 70 DEG C, add mass percent 20% vitamin E ointment and stir, sterilizing, obtains plaster, during use, after tearing plastic sealing pack, pricker is pulled up from shrouding, thrust successively along multiple dosing holes, medicine bag is punctured, then patient lies prone in bed, administration head in anus is inserted along anus place, in insertion process, due to extruding and the sphincteral extruding of hands, ointment in medicine bag is constantly flowed out along dosing holes, and, in insertion process, the expansion wing and soft plastic layer make it possess elasticity, along with the insertion of administration head in anus, the expansion wing scrapes the feces in large intestine inwall and fold, enable the ointment of administration head in anus directly contact intestinal wall as far as possible, be convenient to the administration of internal hemorrhoid on the one hand, another is conveniently also beneficial to partially absorbing of intestinal, increase blood drug level.The ointment that anus external administration head is extruded, is beneficial to the coating of external hemorrhoid.
The present invention once a day, each half an hour, after being used in conjunction 8 days, replys as usual, visits, do not recur after three months.
Example 2
Record certain, man and wife feuds, and irritability is vigorous and cause qi depression to blood stasis, the edge swelling of patient's anus and the purple stasis of blood, and internal hemorrhoid is deviate from, and surface is purple dark rotten to the corn, and sharp ache, anal canal tightens, constipation yellow urine, purplish tongue yellow fur, hesitant pulse.Use the present invention: Radix Rubiae, Folium Callicarpae Formosanae, Folium Artemisiae Argyi, each 45g of Folium Hibisci Mutabilis, Pollen Typhae, Rhizoma Chuanxiong, Olibanum, Myrrha, Herba Artemisiae Anomalae, Sanguis Draxonis, Lasiosphaera Seu Calvatia, each 35g of Cacumen Platycladi, Semen Cassiae, Radix Angelicae Sinensis, Fructus Mori, Semen Pruni, Radix Trichosanthis, Herba Patriniae, each 16g of Aloe, Flos Chrysanthemi 12g.By cataclasm for each active component, clean, dry, put in a hermetic container, add mass percent 75% alcoholic solution, each active component is made to infiltrate vexed bubble after 12 hours, each active component is loaded percolator, after adding mass percent 75% soak with ethanol, starts to collect percolate, collect 1000ml altogether, obtain extractum by after the 75% ethanol percolation liquid heating recovery ethanol collected, extractum is added vegetable oil, makes extractum be dissolved in 500ml vegetable oil, the vegetable oil dissolving in medicine is heated to 70 DEG C, add mass percent 20% vitamin E ointment and stir, sterilizing, obtains plaster, during use, after tearing plastic sealing pack, pricker is pulled up from shrouding, thrust successively along multiple dosing holes, medicine bag is punctured, then patient lies prone in bed, administration head in anus is inserted along anus place, in insertion process, due to extruding and the sphincteral extruding of hands, ointment in medicine bag is constantly flowed out along dosing holes, and, in insertion process, the expansion wing and soft plastic layer make it possess elasticity, along with the insertion of administration head in anus, the expansion wing scrapes the feces in large intestine inwall and fold, enable the ointment of administration head in anus directly contact intestinal wall as far as possible, be convenient to the administration of internal hemorrhoid on the one hand, another is conveniently also beneficial to partially absorbing of intestinal, increase blood drug level.The ointment that anus external administration head is extruded, is beneficial to the coating of external hemorrhoid.
The present invention once a day, each half an hour, after being used in conjunction 10 days, replys as usual.
Example 3
Lee, being reticent, disagrees with people, sulky for a long time and cause qi depression to blood stasis, the swelling of anus edge, hiddenly sees the purple stasis of blood, and internal hemorrhoid is deviate from, and surface is purple dark rotten to the corn, and sharp ache, anal canal tightens, constipation yellow urine.Body of the tongue has ecchymosis, and tongue is white, stringy pulse.Use the present invention: Radix Rubiae, Folium Callicarpae Formosanae, Folium Artemisiae Argyi, each 40g of Folium Hibisci Mutabilis, Pollen Typhae, Rhizoma Chuanxiong, Olibanum, Myrrha, Herba Artemisiae Anomalae, Sanguis Draxonis, Lasiosphaera Seu Calvatia, each 25g of Cacumen Platycladi, Semen Cassiae, Radix Angelicae Sinensis, Fructus Mori, Semen Pruni, Radix Trichosanthis, Herba Patriniae, each 10g of Aloe, Flos Chrysanthemi 10g.By cataclasm for each active component, clean, dry, put in a hermetic container, add mass percent 75% alcoholic solution, each active component is made to infiltrate vexed bubble after 12 hours, each active component is loaded percolator, after adding mass percent 75% soak with ethanol, starts to collect percolate, collect 1000ml altogether, obtain extractum by after the 75% ethanol percolation liquid heating recovery ethanol collected, extractum is added vegetable oil, makes extractum be dissolved in 500ml vegetable oil, the vegetable oil dissolving in medicine is heated to 70 DEG C, add mass percent 20% vitamin E ointment and stir, sterilizing, obtains plaster, during use, after tearing plastic sealing pack, pricker is pulled up from shrouding, thrust successively along multiple dosing holes, medicine bag is punctured, then patient lies prone in bed, administration head in anus is inserted along anus place, in insertion process, due to extruding and the sphincteral extruding of hands, ointment in medicine bag is constantly flowed out along dosing holes, and, in insertion process, the expansion wing and soft plastic layer make it possess elasticity, along with the insertion of administration head in anus, the expansion wing scrapes the feces in large intestine inwall and fold, enable the ointment of administration head in anus directly contact intestinal wall as far as possible, be convenient to the administration of internal hemorrhoid on the one hand, another is conveniently also beneficial to partially absorbing of intestinal, increase blood drug level.The ointment that anus external administration head is extruded, is beneficial to the coating of external hemorrhoid.
The present invention once a day, each half an hour, after being used in conjunction 12 days, replys as usual, visits after five months.
The plaster of object lesson 1: screen 160 routine patients in 4 hospitals, before test 1 week, carries out Continuous Observation to this crowd, record symptom and change, be divided into two groups, experimental group and matched group at random, experimental group uses embodiment 1 products obtained therefrom, and matched group takes the general prescription in background technology
Curative effect situation criterion: cure: use after this product, ulcer surface disappears, and only, defecation color is dark brown for blood, effectively: after taking and using this product, malaise symptoms makes moderate progress, and blood is only; Invalid: after using this product, malaise symptoms is unchanged.Result is as shown in table 1.
Table 1:
| Group | Drug categories | Case load | Efficiently individual quantity | Healing number | Invalid number | Recurrence number | Cure rate | Total effective rate |
| Matched group | General prescription in background technology | 80 | 60 | 28 | 20 | 22 | 35% | 80% |
| Experimental group | The present invention | 80 | 73 | 66 | 7 | 7 | 82.5% | 91.2% |
Ointment of the present invention, with the Folium Artemisiae Argyi of the Folium Callicarpae Formosanae of the Radix Rubiae of removing stasis to stop bleeding, cooling blood for hemostasis, hemostasis and pain-relieving, understands the Folium Hibisci Mutabilis of detumescence for monarch drug; With the Pollen Typhae of hemostasis, the Rhizoma Chuanxiong of pain relieving, Herba Artemisiae Anomalae, the Olibanum of reducing swelling and alleviating pain, Myrrha, the Sanguis Draxonis of granulation promoting, the Lasiosphaera Seu Calvatia of removing toxic substances hemostasis, Cacumen Platycladi is ministerial drug; With the Semen Cassiae of intestine moistening, Radix Angelicae Sinensis, Fructus Mori, Semen Pruni, the Radix Trichosanthis of detumescence and apocenosis, Herba Patriniae, the Aloe of rushing down lower lubrication is adjuvant drug; With Flos Chrysanthemi for making medicine.
Proportioning of the present invention is simple, and easy to use, for qi stagnation and blood stasis type hemorrhoid, the effective speed of external is fast.When the present invention uses, after tearing plastic sealing pack, pricker is pulled up from shrouding, thrust successively along multiple dosing holes, medicine bag is punctured, then patient lies prone in bed, administration head in anus is inserted along anus place, in insertion process, due to extruding and the sphincteral extruding of hands, ointment in medicine bag is constantly flowed out along dosing holes, and, in insertion process, the expansion wing and soft plastic layer make it possess elasticity, along with the insertion of administration head in anus, the expansion wing scrapes the feces in large intestine inwall and fold, enable the ointment of administration head in anus directly contact intestinal wall as far as possible, be convenient to the administration of internal hemorrhoid on the one hand, another is conveniently also beneficial to partially absorbing of intestinal, increase blood drug level.The ointment that anus external administration head is extruded, is beneficial to the coating of external hemorrhoid.The mode of this inside and outside directly administration of the present invention, except being directly administered into focus, can also partly by intestinal absorption, therapeutic effect is good, and responding time is fast.
Claims (4)
1. a qi stagnation and blood stasis type hemorrhoid treating cream, comprise cap (5), the two ends of cap (5) are provided with medicine bag (7), medicine bag (7) is built with ZHICHUANG GAO, it is characterized in that, the medicine activity component of ZHICHUANG GAO according to unit of weight proportioning is: Radix Rubiae, Folium Callicarpae Formosanae, Folium Artemisiae Argyi, each 40-60g of Folium Hibisci Mutabilis, Pollen Typhae, Rhizoma Chuanxiong, Olibanum, Myrrha, Herba Artemisiae Anomalae, Sanguis Draxonis, Lasiosphaera Seu Calvatia, each 25-40g of Cacumen Platycladi, Semen Cassiae, Radix Angelicae Sinensis, Fructus Mori, Semen Pruni, Radix Trichosanthis, Herba Patriniae, each 10-20g of Aloe, Flos Chrysanthemi 10-15g;
The middle part of cap (5) is gradually thin, the outer wrap of the medicine bag (7) of cap (5) side has administration head (3) in anus, anus external administration head (6) is enclosed with in the medicine bag (7) of the opposite side of cap (5), administration head (3) in anus, integratedly on the wall of anus external administration head (6) be provided with some dosing holes (4), be connected between dosing holes (4) with corresponding medicine bag (7), in anus, integrated being provided with in the front end of administration head (3) launches the wing (1), launch to be provided with soft plastic layer (2) between the wing (1) and medicine bag (7) outer wall, the end of anus external administration head (6) is integrated is provided with shrouding (8), shrouding (8) is ellipticity, administration head (3) in anus, anus external administration head (6) is rubber, administration head (3) in anus, be adhesively fixed between anus external administration head (6) and cap.
2. qi stagnation and blood stasis type hemorrhoid treating cream according to claim 1, it is characterized in that, the medicine activity component of ZHICHUANG GAO according to unit of weight proportioning is: Radix Rubiae, Folium Callicarpae Formosanae, Folium Artemisiae Argyi, each 40-50g of Folium Hibisci Mutabilis, Pollen Typhae, Rhizoma Chuanxiong, Olibanum, Myrrha, Herba Artemisiae Anomalae, Sanguis Draxonis, Lasiosphaera Seu Calvatia, each 25-30g of Cacumen Platycladi, Semen Cassiae, Radix Angelicae Sinensis, Fructus Mori, Semen Pruni, Radix Trichosanthis, Herba Patriniae, each 10-15g of Aloe, Flos Chrysanthemi 10-12g.
3. qi stagnation and blood stasis type hemorrhoid treating cream according to claim 1, it is characterized in that, the medicine activity component of ZHICHUANG GAO according to unit of weight proportioning is: Radix Rubiae, Folium Callicarpae Formosanae, Folium Artemisiae Argyi, each 50-60g of Folium Hibisci Mutabilis, Pollen Typhae, Rhizoma Chuanxiong, Olibanum, Myrrha, Herba Artemisiae Anomalae, Sanguis Draxonis, Lasiosphaera Seu Calvatia, each 30-40g of Cacumen Platycladi, Semen Cassiae, Radix Angelicae Sinensis, Fructus Mori, Semen Pruni, Radix Trichosanthis, Herba Patriniae, each 15-20g of Aloe, Flos Chrysanthemi 12-15g.
4., according to the arbitrary described qi stagnation and blood stasis type hemorrhoid treating cream of claim 1-3, it is characterized in that, preparation method is as follows:
A, be prepared as plaster:
By cataclasm for each active component, clean, dry, put in a hermetic container, add mass percent 75% alcoholic solution, each active component is made to infiltrate vexed bubble after 12 hours, each active component is loaded percolator, after adding mass percent 75% soak with ethanol, starts to collect percolate, collect 1000ml altogether, obtain extractum by after the 75% ethanol percolation liquid heating recovery ethanol collected; Extractum is added vegetable oil, makes extractum be dissolved in 500ml vegetable oil, the vegetable oil dissolving in medicine is heated to 70 DEG C, add mass percent 20% vitamin E ointment and stir, sterilizing, obtains plaster;
B, plaster is loaded on and wants in capsule and medicine bag, medicine bag is soft plastic product, in anus, administration head, anus external administration head are inner hollow and the ellipsoid shape rubber of one end open, medicine bag to be filled in respectively in anus in administration head and anus external administration head, in anus, the opening part of administration head, anus external administration head is adhesively fixed the both sides of cap
The shrouding of C, anus external administration head is plugged and connected with pricker; Administration head, the overall plastic sealing pack of anus external administration head in cap and anus.
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| CN201510693051.1A CN105213686A (en) | 2015-10-24 | 2015-10-24 | A kind of qi stagnation and blood stasis type hemorrhoid treating cream |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105963591A (en) * | 2016-07-22 | 2016-09-28 | 铜陵宏正网络科技有限公司 | Plaster for treating haemorrhoids |
| WO2020133084A1 (en) * | 2018-12-25 | 2020-07-02 | 刘颖 | Multi-functional nursing pillow for use in intensive care unit |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1381259A (en) * | 2002-05-16 | 2002-11-27 | 高学山 | Medicine for treating diseases of rectum and anus |
| CN201414996Y (en) * | 2009-03-13 | 2010-03-03 | 赵学 | Procto disease treatment and procto health care device |
| CN203043311U (en) * | 2013-02-25 | 2013-07-10 | 胡国伟 | Gynecological doser |
| CN103285181A (en) * | 2013-06-01 | 2013-09-11 | 吕军荣 | Traditional Chinese medicine composition for treating qi-stagnation and blood stasis type haemorrhoids |
| CN103655943A (en) * | 2013-12-04 | 2014-03-26 | 孙强 | Traditional Chinese medicine for treating qi-stagnation and blood-stasis type hemorrhoids |
-
2015
- 2015-10-24 CN CN201510693051.1A patent/CN105213686A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1381259A (en) * | 2002-05-16 | 2002-11-27 | 高学山 | Medicine for treating diseases of rectum and anus |
| CN201414996Y (en) * | 2009-03-13 | 2010-03-03 | 赵学 | Procto disease treatment and procto health care device |
| CN203043311U (en) * | 2013-02-25 | 2013-07-10 | 胡国伟 | Gynecological doser |
| CN103285181A (en) * | 2013-06-01 | 2013-09-11 | 吕军荣 | Traditional Chinese medicine composition for treating qi-stagnation and blood stasis type haemorrhoids |
| CN103655943A (en) * | 2013-12-04 | 2014-03-26 | 孙强 | Traditional Chinese medicine for treating qi-stagnation and blood-stasis type hemorrhoids |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105963591A (en) * | 2016-07-22 | 2016-09-28 | 铜陵宏正网络科技有限公司 | Plaster for treating haemorrhoids |
| WO2020133084A1 (en) * | 2018-12-25 | 2020-07-02 | 刘颖 | Multi-functional nursing pillow for use in intensive care unit |
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