CN105232366A - Moisturizing and anti-wrinkle lotion containing konjac ceramide and luffa juice and production method of moisturizing and anti-wrinkle lotion - Google Patents
Moisturizing and anti-wrinkle lotion containing konjac ceramide and luffa juice and production method of moisturizing and anti-wrinkle lotion Download PDFInfo
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- CN105232366A CN105232366A CN201510597458.4A CN201510597458A CN105232366A CN 105232366 A CN105232366 A CN 105232366A CN 201510597458 A CN201510597458 A CN 201510597458A CN 105232366 A CN105232366 A CN 105232366A
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- fructus luffae
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- petroleum ether
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- 229940106189 ceramide Drugs 0.000 title claims abstract description 55
- ZVEQCJWYRWKARO-UHFFFAOYSA-N ceramide Natural products CCCCCCCCCCCCCCC(O)C(=O)NC(CO)C(O)C=CCCC=C(C)CCCCCCCCC ZVEQCJWYRWKARO-UHFFFAOYSA-N 0.000 title claims abstract description 55
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- 229920002752 Konjac Polymers 0.000 title claims abstract description 45
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- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
Moisturizing and anti-wrinkle lotion containing konjac ceramide and luffa juice mainly comprises, by weight, 4-6 parts of konjac ceramide extract, 90-95 parts of original luffa juice and 0.5-1 part of honeysuckle essence, wherein the ceramide content in the konjac ceramide extract is 3-5%, and the luffa juice is liquid naturally flowing out of a cut-off fresh luffa ground stem. A production method of the moisturizing and anti-wrinkle lotion includes: mixing the konjac ceramide extract, the luffa juice and the honeysuckle essence, filtering, and sterilizing to obtain the moisturizing and anti-wrinkle lotion. The moisturizing and anti-wrinkle lotion has good moisturizing and nourishing, anti-wrinkle, anti-aging and antibacterial and anti-inflammation effects.
Description
Technical field
The present invention relates to a kind of cosmetic products, be specifically related to a kind of crease-resistant skin care item containing konjak ceramide and Fructus Luffae water.
Background technology
For a long time, ceramide (Ceramide) is only considered to a kind of lipid components in normal bio membrane structure, be distributed in the skin of Lipid Bilayer Structure, rich content in axoneure especially brain cell, and in the growth of neurocyte, regeneration and mending course, there is certain effect.In cells involved in recent years, the research of signal transduction then finds, play important second message,second messenger's effect in the biological effect that ceramide is induced at cytokine profiles, vitamin D, Fas and CD28 part etc., participate in Growth of Cells, propagation, differentiation, the multiple physiology of apoptosis and damage and pathological process thus.The further research of medical science and the academias such as biological also shows, the 26S Proteasome Structure and Function of ceramide and skin also has extremely close relation, and skin reparation, anti-ageing wait for a long time in play an important role.Therefore, ceramide is for the research and production of cosmetics.A kind of Rhizoma amorphophalli moisturizing astringent and preparation method thereof (CN201110215963.X) disclosed in Chinese patent, the Konjac glucomannan made primarily of Rhizoma amorphophalli powder is made, and product has good moistening effect.
Fructus Luffae (formal name used at school: Luffacylindrica), Delta of the Pearl River Fructus Luffae refers in particular to anistree melon, is a kind of cucurbitaceous plant originating in India, also known as snake melon, is widely cultivated in East Asia Region.For Cucurbitaceae climbs up by holding on to herbaceous plant, Fructus Luffae root system is powerful.The climing property of stem, five ribs, green, main climing and lateral bine growth is all in great numbers, stipes tool divides branch tendril, easily raw adventitious root.In all have both at home and abroad distribution and cultivation.Fruit is summer vegetable, and contained all kinds of nutrition is higher in melon food, and the materials such as contained saponins, luffein, lymphatic temperament, wood glue, citrulline, xylan and interferon have certain special role.Not raw-eaten, also can hyoscine, the effect of have refrigerant, diuresis, invigorating blood circulation, stimulating the menstrual flow, detoxify, also has the effect of antiallergic, beauty treatment.The cosmetics utilizing Fructus Luffae to make appear in the newspapers, Chinese patent is disclosed " a kind of skincare lotion and preparation method thereof " (201310376168.8), containing the following material of Fructus Luffae extracting solution: Oleum Camelliae, Fructus Cucumidis sativi juicing, Rhizoma Bletillae extraction solution, synthesis squalane etc., there is character gentleness, safety is high, beauty and skin care is made to become safe and effective, trace element wherein in plant, glycoside, polysaccharide etc. can nourishes rough skin to the useful nutrient substance of human body, make face become smooth delicacy.
Cosmetics and skincare product containing Rhizoma amorphophalli and Fructus Luffae composition also has report, Chinese patent application disclosed a kind of " preparation method of konjak facial cleanser " (201210160044.1), by purification Rhizoma amorphophalli micropowder, sodium carboxymethyl cellulose, distilled water, Sucus Cucumidis sativi, Sucus Luffae, vitamin E and Margarita powder by slurrying, squeeze the juice, the technique such as emulsifying is prepared from, have clean, deoil, de-sludging, whitening, go speckle, crease-resistant function.But just existing Rhizoma amorphophalli or Fructus Luffae be used for cosmetics all need to add multiple other Chinese herbal medicine or other plant extract, just can reach more satisfactory effect, and Rhizoma amorphophalli extract mostly is the mixed extracts such as Konjac glucomannan, and carried out dilution process more, ceramide type content of material is impure, have impact on moistening effect.Fructus Luffae water used also adopt has carried out dilution process more, have impact on function that is crease-resistant and anti-inflammation.
Summary of the invention
The object of the present invention is to provide a kind of konjak ceramide Fructus Luffae water moisture-keeping crease-shedding liquid, it has good moisturizing and nourishing, skin wrinkle resisting defying age and antibacterial and anti-inflammation functions.
For achieving the above object, embodiment of the present invention are: a kind of konjak ceramide Fructus Luffae water moisture-keeping crease-shedding liquid, the main component containing following weight portion: konjak ceramide extract 4-6 part, Fructus Luffae water stock solution 90-95 part, honeysuckle compound 0.5-1 part, in described konjak ceramide extract, ceramide content is 3-5%, and described Fructus Luffae water is the liquid that cutting fresh Fructus Luffae ground rattan flows out naturally.
As optimization, also containing sodium carboxymethyl cellulose 0.05-0.1 part in konjak ceramide Fructus Luffae water moisture-keeping crease-shedding liquid.
The preparation method of described konjak ceramide extract comprises the following steps:
(1) Rhizoma amorphophalli powder is put into round-bottomed flask, add the ethanol that concentration is 95%, solid-to-liquid ratio 1:10, round-bottomed flask connects condensing tube, and at 80 DEG C, condensing reflux extracts 8h, after extraction terminates, centrifugal filter paper filtering, and with petroleum ether extraction three times, gets petroleum ether layer and adds a small amount of petroleum ether after evaporate to dryness in a rotary evaporator, pour small beaker into after ultrasonic on ultrasonic cleaner, after solvent volatilizees naturally, obtain the crude extract of konjak ceramide class material;
(2) crude extract of konjak ceramide class material is dissolved in petroleum ether, silica gel column chromatography carries out preliminary purification, column chromatography silica gel is first at 100 DEG C of activation 1h, after being cooled to room temperature, use petroleum ether upper prop, petroleum ether solution containing ceramide crude product is slowly loaded to column top, carries out gradient elution with the petroleum ether of different ratio and ethyl acetate mixed solvent respectively.Single injected sampling 20mg/g medium, flow velocity 2ml/min, collects eluent, and volatilization, except desolventizing, merges and obtains ceramide extract.
In step (2), when carrying out gradient elution with petroleum ether and ethyl acetate mixed solvent, each petroleum ether and ethyl acetate volume ratio are respectively 95:5,7:3,6:4.
The extracting method of described Fructus Luffae water stock solution is, get Fructus Luffae rattan cut-out on the ground, inserted by otch in container, the liquid naturally flowed out, through precipitation, filters, sterilizes and obtain Fructus Luffae water stock solution.Optimize, described Fructus Luffae rattan is the Fructus Luffae rattan also not tying Fructus Luffae before and after the Mid-autumn Festival.
The honeysuckle compound of described honeysuckle compound extraction by steam distillation.
Compound method of the present invention is, is mixed by konjak ceramide extract with Fructus Luffae water, honeysuckle compound, filter, sterilization.
In the present invention, ceramide has very strong associated water molecule ability, and it maintains moisture of skin by forming network structure in horny layer, and therefore, it has the effect of maintenance moisture of skin; Skin is in aging course, and lipid synthesis declines, and in horny layer, ceramide content reduces.Use ceramide that ceramide content in horny layer of epidermis can be made to increase, xerosis cutis, desquamation, the situation such as coarse can be improved; Ceramide can increase epidermal keratinocytes layer thickness simultaneously, improves skin moisture holding capacity, reduces wrinkle, strengthens skin elasticity, delay skin aging.
In the present invention, containing effective ingredient such as abundant sugar, plant mucilage, vitamin and mineral in Fructus Luffae water stock solution, can maintain horny layer normal moisture content, slow down dehydration and prolongation hydration, can supplement the moisture of skin necessity, keep skin water tender, fine and smooth; This Fructus Luffae water contains a large amount of nature moisturizing factor, and not glutinous greasy moisturizing ingredient effectively can be releived and be tightened dry skin, and make face skin keep moistening, high resilience, the colour of skin is beautiful, ruddy, clean, pale; Fructus Luffae water can enhance metabolism, and soft absorption is useless cutin always, and remove deep layer dirt, check melanin Hemapoiesis, effectively can improve coarse skin wrinkly, makes skin reply children tender bright and clean, makes skin quality become soft and moist glossy; Fructus Luffae glassware for drinking water has promoting blood circulation to remove obstruction in the collateral, the effect of heat clearing away skin moistening, often uses the blackhead, acne etc. that effectively can dispel skin of face; Fructus Luffae aqueous is sweet, gentle, and scalable face sebum secretion, has clearly to skin of face, convergence, calm, the function of balance.
Flos Lonicerae in the present invention has effect of heat-clearing and toxic substances removing, dredge the meridian passage.Do not injure skin with the honeysuckle compound of extraction by steam distillation, fragrance is soft, can take out stains, cleaning skin make skin keep higher water content to strengthen effect that skin vitality reaches delay skin aging.Certain curative effect is had to seborrheic dermatitis scytitis.
Above-mentioned effective ingredient coordinates, and makes the present invention have good moisturizing and nourishing, crease-resistant, defying age and antibacterial and anti-inflammation functions.
Detailed description of the invention
embodiment 1:
A kind of konjak ceramide Fructus Luffae water moisture-keeping crease-shedding liquid, is configured by following methods and forms:
(1) take Rhizoma amorphophalli powder and put into round-bottomed flask, add the ethanol of 95% according to 1:10 solid-to-liquid ratio, round-bottomed flask connects 40cm condensing tube, under 80 DEG C of conditions, condensing reflux extracts 8h.After extraction terminates, centrifugal (4000 turns, 10min) with filter paper filtering, and with certain volume petroleum ether extraction three times, get petroleum ether layer and add a small amount of petroleum ether after evaporate to dryness in a rotary evaporator, pour small beaker into after ultrasonic on ultrasonic cleaner, solvent is the crude extract of required konjak ceramide class material after naturally volatilizing;
(2) crude extract of konjak ceramide class material is dissolved in the petroleum ether of certain volume, is carrying out preliminary purification containing on the chromatographic column of 20g silica gel.Column chromatography silica gel is first at 100 DEG C of activation 1h.After being cooled to room temperature, use petroleum ether upper prop, silica gel balances a period of time in petroleum ether.Petroleum ether solution containing ceramide crude product is slowly loaded to column top.Use petroleum ether respectively: ethyl acetate (95:5), petroleum ether: ethyl acetate (7:3), petroleum ether: ethyl acetate (6:4) carries out gradient elution.Single injected sampling 20mg/g medium, flow velocity 2ml/min.Collect eluent, volatilization, except desolventizing, merges and obtains konjak ceramide extract;
(3) get the Fructus Luffae rattan also not tying Fructus Luffae before and after the Mid-autumn Festival, from overhead 30 centimeters cut-outs, inserted by otch in bottle, place diel, by gained liquid precipitation 1-5 hour, filter, ultraviolet sterilization obtains Fructus Luffae water stock solution, and 0-4 DEG C of stored refrigerated is for subsequent use;
(4) get konjak ceramide extract 4g, Fructus Luffae water stock solution 95g, honeysuckle compound 0.3g, first konjak ceramide adding distil water is mixed with the aqueous solution of 5%, then mixes with Fructus Luffae water stock solution and honeysuckle compound, homogenizing, filter, ultraviolet sterilization, pack.Honeysuckle compound is the honeysuckle compound of extraction by steam distillation.
embodiment 2:
In the step (4) of embodiment 1, get konjak ceramide extract 6g, Fructus Luffae water stock solution 95g, honeysuckle compound 0.3g, sodium carboxymethyl cellulose 0.08g.First konjak ceramide adding distil water is mixed with the aqueous solution of 5%, then mixes with Fructus Luffae water stock solution, honeysuckle compound and sodium carboxymethyl cellulose, homogenizing, filter, ultraviolet sterilization, pack.Other method is identical with embodiment 1.
embodiment 3
In the step (4) of embodiment 1, get konjak ceramide extract 5g, Fructus Luffae water stock solution 95g, honeysuckle compound 0.5g, sodium carboxymethyl cellulose 0.1g.First konjak ceramide adding distil water is mixed with the aqueous solution of 5%, then mixes with Fructus Luffae water stock solution, honeysuckle compound and sodium carboxymethyl cellulose, homogenizing, filter, ultraviolet sterilization, pack.Other method is identical with embodiment 1.
embodiment 4:
In the step (4) of embodiment 1, get konjak ceramide extract 5g, Fructus Luffae water stock solution 90g, honeysuckle compound 0.1g, sodium carboxymethyl cellulose 0.05g.First konjak ceramide adding distil water is mixed with the aqueous solution of 5%, then mixes with Fructus Luffae water stock solution, honeysuckle compound and sodium carboxymethyl cellulose, homogenizing, filter, ultraviolet sterilization, pack.Other method is identical with embodiment 1.
Claims (8)
1. a konjak ceramide Fructus Luffae water moisture-keeping crease-shedding liquid, it is characterized in that, the main component containing following weight portion: konjak ceramide extract 4-6 part, Fructus Luffae water stock solution 90-95 part, honeysuckle compound 0.5-1 part, in described konjak ceramide extract, ceramide content is 3-5%, and described Fructus Luffae water is the liquid that cutting fresh Fructus Luffae ground rattan flows out naturally.
2. konjak ceramide Fructus Luffae water moisture-keeping crease-shedding liquid according to claim 1, is characterized in that, containing sodium carboxymethyl cellulose 0.05-0.1 part.
3. konjak ceramide Fructus Luffae water moisture-keeping crease-shedding liquid according to claim 1, it is characterized in that, described konjak ceramide extract is made up of the method comprising the following steps:
(1) Rhizoma amorphophalli powder is put into round-bottomed flask, add the ethanol that concentration is 95%, solid-to-liquid ratio 1:10, round-bottomed flask connects condensing tube, and at 80 DEG C, condensing reflux extracts 8h, after extraction terminates, centrifugal filter paper filtering, and with petroleum ether extraction three times, gets petroleum ether layer and adds a small amount of petroleum ether after evaporate to dryness in a rotary evaporator, pour small beaker into after ultrasonic on ultrasonic cleaner, after solvent volatilizees naturally, obtain the crude extract of konjak ceramide class material;
(2) crude extract of konjak ceramide class material is dissolved in petroleum ether; silica gel column chromatography carries out preliminary purification; column chromatography silica gel is first at 100 DEG C of activation 1h; after being cooled to room temperature; use petroleum ether upper prop; petroleum ether solution containing ceramide crude product is slowly loaded to column top, carries out gradient elution with the petroleum ether of different ratio and ethyl acetate mixed solvent respectively; Single injected sampling 20mg/g medium, flow velocity 2ml/min, collects eluent, and volatilization, except desolventizing, merges and obtains ceramide.
4. konjak ceramide Fructus Luffae water moisture-keeping crease-shedding liquid according to claim 3, is characterized in that, in step (2), when carrying out gradient elution with petroleum ether and ethyl acetate mixed solvent, each petroleum ether and ethyl acetate volume ratio are respectively 95:5,7:3,6:4.
5. konjak ceramide Fructus Luffae water moisture-keeping crease-shedding liquid according to claim 1, it is characterized in that, the extracting method of described Fructus Luffae water stock solution is, get the Fructus Luffae aerial stem of plant to cut off, inserted by otch in container, the liquid naturally flowed out is through precipitation, filter, sterilize and obtain Fructus Luffae water stock solution.
6. konjak ceramide Fructus Luffae water moisture-keeping crease-shedding liquid according to claim 5, it is characterized in that, described Fructus Luffae rattan is the Fructus Luffae rattan also not tying Fructus Luffae before and after the Mid-autumn Festival.
7. konjak ceramide Fructus Luffae water moisture-keeping crease-shedding liquid according to claim 1, is characterized in that, the honeysuckle compound of described honeysuckle compound extraction by steam distillation.
8. a preparation method for konjak ceramide Fructus Luffae water moisture-keeping crease-shedding liquid as claimed in claim 1, is characterized in that, mixed by konjak ceramide extract with Fructus Luffae water, honeysuckle compound, filter, sterilization.
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| CN102293723A (en) * | 2011-07-30 | 2011-12-28 | 福建农林大学 | Konjak moisture retention lotion and its preparation method |
| CN102351730A (en) * | 2011-10-22 | 2012-02-15 | 恩施清江生物工程有限公司 | Method for preparing ceramide from konjac fly powder |
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| CN102293723A (en) * | 2011-07-30 | 2011-12-28 | 福建农林大学 | Konjak moisture retention lotion and its preparation method |
| CN102351730A (en) * | 2011-10-22 | 2012-02-15 | 恩施清江生物工程有限公司 | Method for preparing ceramide from konjac fly powder |
| CN102657593A (en) * | 2012-05-22 | 2012-09-12 | 重庆市彭水县天娇农业开发有限公司 | Preparation method of konjak facial cleanser |
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